According to a study published in the November 6, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology, older people who are sleepy during the day or lose interest in activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia.

People with the syndrome walk slowly and report memory problems, but they do not have a mobility handicap or dementia. Motoric cognitive risk syndrome is a condition that can develop before dementia.

What The Study Found?

The study found that people with excessive daytime sleepiness and a lack of enthusiasm to get things done were more likely to develop the syndrome than people without those sleep-related issues. The study does not prove that these sleep-related issues cause the syndrome, it only shows an association.

“Our findings emphasize the need for screening for sleep issues,” said study author Victoire Leroy, MD, PhD, of Albert Einstein College of Medicine in the Bronx, New York. “There’s potential that people could get help with their sleep issues and prevent cognitive decline later in life.”

How Was It Conducted?

The study included 445 participants, with an average age of 76, who did not have dementia. Participants completed sleep surveys at the beginning of the trial. They were queried about memory problems, and their walking pace was measured on a treadmill at the beginning of the study and then once a year for the next three years.

The sleep assessment included questions about how frequently people had difficulties sleeping because they woke up in the middle of the night, couldn't fall asleep within 30 minutes, or felt too hot or cold, as well as whether they used sleep aids. The question to assess excessive daytime drowsiness asks how frequently people have had problems remaining awake when driving, eating meals, or were engaged in any other activity.

The Findings

In total, 177 participants fit the category of bad sleepers, whereas 268 satisfied the definition of good sleepers.

At the outset of the trial, 42 participants had motoric cognitive risk syndrome. Throughout the trial, 36 more persons got the condition.

35.5% of patients who experienced extreme daytime sleepiness and a lack of enthusiasm developed the syndrome, compared to 6.7% who did not. After accounting for other factors that could influence the risk of the syndrome, such as age, depression, and other health conditions, researchers discovered that people with excessive daytime sleepiness and a lack of enthusiasm were more than three times more likely to develop the syndrome than those who did not have those sleep-related issues.

“More research needs to be done to look at the relationship between sleep issues and cognitive decline and the role played by motoric cognitive risk syndrome,” Leroy said. “We also need studies to explain the mechanisms that link these sleep disturbances to motoric cognitive risk syndrome and cognitive decline.”

A limitation of the study is that participants reported their own sleep information, so they may not have remembered everything accurately.

The study was supported by the National Institute on Aging.

In 2022, there were around 19,976,499 cancer cases diagnosed from around the world, notes the World Cancer Research Fund. Out of them, 10,311,610 were men, and 9,664,889 were women. In 2024, several reports say that there were over 19 million new global cases in that year. The cases of cancer are rising, so is there any way one can stay one step ahead of it?

While it is important to get screenings done frequently, especially if one has a family history of cancer, there could be certain red flags, one must look out for to book an appointment with oncology.

Here are the cancer red flag one must keep a look out for:

Persistent Fatigue

Persistent fatigue remains one of the most overlooked symptoms of oncology. This is not like a routine tiredness, this is a kind of exertion that stays despite rest, balanced meals, and time off. Data from 2022-24 shows that over 30% of early stage cancer patients reported unexplained fatigue prior to diagnosis.

Unexplained Weight Loss

Oncologists explain that over 40% of newly diagnosed gastrointestinal and lung cancer patients experienced weight loss. This could happen due to metabolic changes caused by tumors, which can alter energy absorption and consumption, often suppressing appetite and leading to a rapid loss of body fat.

When to see a doctor? If you have lost more than 5% of your body weight in under 6 to 8 weeks, it is important that you seek immediate medical attention.

Chronic Pain

If there is a pain that does not go away, it could be because of cancer. Many patients have complained of persistent pain as one of the fist symptoms of their cancers. This is particularly true for back pain, which is common in pancreatic or ovarian cancer. Bone pain too is common in metastasis, and pelvic pain is common in uterine or colorectal cancer.

Skin Changes

Not all cancers start inside the body, some also show up on the skin. These changes could be new moles, non-healing wounds, or changes in pigmentation. In fact, unusual rashes also signal changes like skin cancer.

Changes In Bowel And Bladder Habits

If you experiences changes in your bowel and bladder habits and find blood in your stool or urine, it is best to see a doctor. Colorectal, bladder and prostate cancers often start subtly. Before it becomes serious, keeping a track of your bowel and bladder habits could prevent the cancer from spreading.

Lump Or Thickening Of Body

While lumps could be benign, they are also one of earliest signs cancer. For instance, the early detection of breast cancer and testicular cancer are from lumps, which are observed while self examination. In fact, the early detection, thanks to self examination, has even increased by 22%.

Persistent Cough

While this may be a season of virus and flu, but if your cough does not go away, it may be a serious sign. If you find blood in your cough, see a doctor, take scans. If you are a smoker, you may be more prone to early stage throat cancer.

Headache That Does Not Go Away

There could be certain neurological issues, including a stubborn headache that does not go away. This may be an indication of a tumor in the brain.

If you have any of these stubborn symptoms, it is best to book a doctor's appointment and go for a screening.

Note: Health and Me is not a substitute for doctor's advice, please consult a registered doctor, if you face any of these symptoms.

Delhi's AQI on Tuesday morning seemed to be doing somewhat better than Monday morning. The AQI has brought some relief to the residents who had been dealing with 'severe' pollution levels, with visibility being hit. As per Tuesday's AQI, according to Central Pollution Control Board (CPCB), Delhi's air pollution stood at 381 AQI as of 6.30 am. This has placed the air quality in the 'very poor' category.

While it has become a habit of many to check AQI before stepping out of the house, how many of us actually understand what AQI really means?

Recently, Delhi's Chief Minister Rekha Gupta claimed that AQI and temperature are the same. At a summit hosted by a news channel, Delhi CM Gupta referred to AQI as "temperature".

Such statements could further lead to misconceptions, and add to everyday confusions. Health and Me is breaking down what AQI really means and why is it not the same as temperature.

How Air Quality Index Work And What It Means

As the Delhi CM claimed that AQI is like temperature and could be "measured using any instrument", is not true. Though it is understandable why such comparisons may have been drawn as you can easily check the AQI report on your phones, like we do with temperature.

However, in real sense, AQI or the air quality index is a tool used for communicating outdoor air quality and health. The AQI includes six-color coded categories, each of which corresponds to a range of index values. The higher the AQI value, the greater the level of air pollution and the greater the health concern.

Air quality is made of dust and small particles like PM2.5 and PM10, along with gases like nitrogen dioxide from car exhaust, sulphur dioxide from factories, and carbon monoxide from vehicles. The levels are measured through specialized machines. In India, the standard of the machines are carried out by the Central Pollution Control Board or CPCB.

What Makes Delhi So Polluted?

As per a review of Delhi's air quality from 1990 to 2022, published in Sustainability (MDPI), an open access journal, these are the following sources of Delhi's Air Pollution:

• Transports emit around 10 to 30% of pollution. This includes all road, rail, and aviation modes and combustion of petrol, diesel, and gas.

• Dust make up another 10 to 30% of pollution. Dust from resuspension on the roads and construction activities.

• All industries, including small, medium, and large industries, including power plants and brick kilns lead to 10 to 30% of pollution.

• In summers, all residential activities, including cooking, lighting, and heating activities lead to 10% of pollution, whereas in winter, it makes up for 30%.

• Waste burning, including residential sides and landfills leads to 5 to 15% of pollution.

Power plants from outside the city leads to less than 7% of pollution. Dust storms contribute to less than 5% of pollution. Agricultural residue burning, which is a seasonal source of pollution leads to less than 3% of pollution, whereas firecrackers, another seasonal source, leads to less than 1% of pollution.

Earlier in November, the Public Health Ontario's (PHO) data revealed that Ontario and Canada as a whole could be in a "very tough" flu season this year, thanks to the Influenza A or the flu A. The PHO data revealed a 1.8% rise in influenza cases in the last week of October. Now, amid the influenza A outbreak, 3 children have died from the same in Ottawa and Eastern Ontario region.

Influenza A: Can Flu Kill People?

As per the infectious physician at the Johns Hopkins University Center for Health Security, as reported in Scientific American, "Dying from the flu is not like dying from a bullet or a black widow spider bite. The presence of the virus itself isn't going to be what kills you. An infectious disease always has a complex interaction with its host.”

Once the virus enters someone's body usually via their eyes, nose, or mouth, the influenza virus begins hijacking human cells in the nose and throat to make copies of itself. This triggers a strong response from the immune system, and sends battalions of white blood cells, antibodies and inflammatory molecules to eliminate the threat.

T cells work by targeting and destroying virus-infected tissue, especially in the respiratory tract and lungs where the infection usually settles. In most healthy adults, this response clears the virus and leads to recovery within days or weeks. In some cases, however, the immune reaction becomes excessive, damaging large areas of lung tissue and impairing oxygen delivery to the blood, which can cause hypoxia and, in severe cases, death.

What Is Influenza A?

As per the National Institutes of Health, US, influenza viruses that contains single-stranded RNA that are classified into three types: A, B, and C. Type A and B cause annual epidemics and even pandemics, while type C is a less common disease.

As per the Centers for Disease Control and Prevention (CDC), Influenza A viruses are descendants of the 2009 H1N1 pandemic virus that emerged in the spring of 2009 and caused a flu pandemic. These viruses, scientifically called the "A(H1N1)pdm09 virus," and more generally called "2009 H1N1," have continued to circulate seasonally since 2009 and have undergone genetic and antigenic changes.

Influenza A(H3N2) viruses also change genetically and antigenically. Influenza A(H3N2) viruses have formed many separate, genetically different clades in recent years that continue to co-circulate.

It is a fast-spreading respiratory virus responsible for seasonal flu outbreaks and, at times, global pandemics. It changes quickly through genetic shifts, which makes new strains harder to predict and control. The virus is grouped based on surface proteins called hemagglutinin and neuraminidase, with H1N1 and H3N2 among the most common strains in circulation. It spreads mainly through coughs, sneezes, or close contact and often comes on suddenly, causing fever, cough, body pain, and extreme tiredness. In some cases, it can lead to serious complications, especially in vulnerable groups.

Influenza A: Common Signs And Symptoms

• Fever or chills
• Dry cough
• Sore throat
• Headache
• Fatigue
• Some people could also get symptoms like diarrhea or vomiting, especially kids.

The symptoms usually appear 1 to 4 days after exposure and could linger for a week.