According to a study published in the November 6, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology, older people who are sleepy during the day or lose interest in activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia.

People with the syndrome walk slowly and report memory problems, but they do not have a mobility handicap or dementia. Motoric cognitive risk syndrome is a condition that can develop before dementia.

What The Study Found?

The study found that people with excessive daytime sleepiness and a lack of enthusiasm to get things done were more likely to develop the syndrome than people without those sleep-related issues. The study does not prove that these sleep-related issues cause the syndrome, it only shows an association.

“Our findings emphasize the need for screening for sleep issues,” said study author Victoire Leroy, MD, PhD, of Albert Einstein College of Medicine in the Bronx, New York. “There’s potential that people could get help with their sleep issues and prevent cognitive decline later in life.”

How Was It Conducted?

The study included 445 participants, with an average age of 76, who did not have dementia. Participants completed sleep surveys at the beginning of the trial. They were queried about memory problems, and their walking pace was measured on a treadmill at the beginning of the study and then once a year for the next three years.

The sleep assessment included questions about how frequently people had difficulties sleeping because they woke up in the middle of the night, couldn't fall asleep within 30 minutes, or felt too hot or cold, as well as whether they used sleep aids. The question to assess excessive daytime drowsiness asks how frequently people have had problems remaining awake when driving, eating meals, or were engaged in any other activity.

The Findings

In total, 177 participants fit the category of bad sleepers, whereas 268 satisfied the definition of good sleepers.

At the outset of the trial, 42 participants had motoric cognitive risk syndrome. Throughout the trial, 36 more persons got the condition.

35.5% of patients who experienced extreme daytime sleepiness and a lack of enthusiasm developed the syndrome, compared to 6.7% who did not. After accounting for other factors that could influence the risk of the syndrome, such as age, depression, and other health conditions, researchers discovered that people with excessive daytime sleepiness and a lack of enthusiasm were more than three times more likely to develop the syndrome than those who did not have those sleep-related issues.

“More research needs to be done to look at the relationship between sleep issues and cognitive decline and the role played by motoric cognitive risk syndrome,” Leroy said. “We also need studies to explain the mechanisms that link these sleep disturbances to motoric cognitive risk syndrome and cognitive decline.”

A limitation of the study is that participants reported their own sleep information, so they may not have remembered everything accurately.

The study was supported by the National Institute on Aging.

The U-WIN (Universal Immunization Win) platform has been transformative and has helped India tackle the concerning burden of zero-dose children, said Dr NK Arora, an immunization expert and member of the National Technical Advisory Group on Immunisation in India (NTAGI).

In an exclusive conversation with HealthandMe during World Immunization Week 2026, Dr Arora, Executive Director of The INCLEN Trust International, traced the journey of the U-WIN portal and explained how it has strengthened vaccine uptake in the country.

U-WIN is a digital platform and app to help people find vaccination centers near their residences, manage vaccination appointments at health facilities, and maintain vaccination records.

Dr Arora noted that the U-WIN portal created a digital ecosystem that played a critical role in registration, appointment scheduling, vaccine tracking, and real-time monitoring.

The Origin Of U-WIN

U-Win was launched in October 2024 and is available in 12 languages, including English.

Dr Arora, also the chair of the COVID-19 and HPV vaccine working group, shared that during the deadly COVID pandemic in 2020—around July—it became very clear that to vaccinate 140 crore people, some kind of IT platform is needed that will track individuals who had been vaccinated, especially when they needed their second dose, and later, booster doses.

“Everything started somewhere around July 2020, and by January 2021, we had the Co-WIN platform. By mid-April, things were streamlined. The platform gives us a long list of individuals who have been vaccinated. It also helps to know who has been left out of the vaccination.

“It is like a registry of human beings who are getting immunized. And we could send reminders, we could send certificates, and we can also tell the individual when to get their second and third dose,” the expert said.

He noted that as COVID became less intense toward the end of 2021, serious discussions began on using the same platform for routine immunization. This is where the concept of U-WIN came in 2022. It has now been piloted and is gradually being used.

U-WIN: Closing the Gap For Missed and Zero-Dose Children

The UWIN now has the mechanism to ensure that immunization is completed for everyone who registers. One user can register up to 10 people in one mobile number, including citizens/guardians, pregnant women, infants (0-1 years), children (1-7 years), and adolescents (7-19 years).

“The key issue is that tracking provides two or three important inputs. First, it ensures that everyone is getting vaccinated and that it is not dependent on memory. There is a proper record—whether a person or child has received vaccines and what their current status is, including whether the schedule is complete,” Dr Arora said.

“Second, one of the main reasons for missing or delaying the next dose was that mothers often did not remember. Fathers contributed very little to this process, but they also became involved because of the reminder system,” he added.

Another important role of U-WIN is tackling the so-called zero-dose children—those who have never been vaccinated.

“About 4–5 per cent of our eligible population falls into this category, meaning they have not received even the first pentavalent dose. On the face of it, 4–5 per cent may not seem like a huge problem. But when we look at the absolute numbers—out of 26 million—it translates into a very large number, which we cannot afford to miss. So tracking helps identify these children through the micro-plan system”.

U-WIN Enables Life-course Immunization

Also read: World Immunization Week: Vaccines Are Like Insurance, They’re Safe—Take Them, Says Dr NK Arora

“When a child is vaccinated, we know when boosters are due—at one and a half years, then at five years. But none of us remembers this. Even among well-informed parents, this is often forgotten. This system helps address that gap,” Dr. Arora said.

Further, when the same individual becomes eligible for vaccines like HPV—typically between 9 and 14 years—there is again a gap that needs to be addressed.

Certification is another benefit, as it creates a documented process, particularly for programs like oral polio vaccination.

Dr. Arora highlighted that in case of any future pandemic-like situation that requires repeated vaccinations, “we have a mechanism in place”.

“This IT platform has truly transformed the system. There is also a lot of discussion about using similar platforms for TB patients, pregnant women, and other flagship programs like non-communicable diseases. So, for India, digitalisation is at its best when we talk about U-WIN.”

Summer can invite a plethora of health problems in children. Moreover, dehydration is commonly seen when the body loses more fluids than it takes in. It is important to understand that early or subclinical dehydration can present as fatigue, irritability and reduced appetite, often going unnoticed by parents. Hence, parents need to detect the signs and symptoms of dehydration in children and seek timely help. Parents should follow the vital measures suggested by experts and safeguard their well-being.

Are children more prone to dehydration in a heatwave?

Dr Tushar Parikh, Senior Consultant Neonatologist and Head of Department at Motherhood Hospital, Kharadi, Pune, in an interaction with Health and Me, spoke about dehydration in children and how parents can identify it promptly.

“As temperatures rise during the summer months, dehydration becomes a common yet often overlooked problem in children. Dehydration occurs when the body does not have enough fluids to function properly. The causes can include inadequate fluid intake, sweating, prolonged outdoor play, and illnesses such as fever, vomiting and diarrhoea,” Dr Parikh explained.

Children are at a greater risk of dehydration as fluid loss occurs quickly through sweat. Severe dehydration is easier to identify, but early or ‘subclinical’ dehydration often goes unnoticed, silently affecting a child’s health and behaviour. Parents may assume that their child is simply tired or irritable due to the heat, but these could be early warning signs of fluid imbalance. Dehydration is often the last thing that comes to mind. However, it is frequently considered a minor issue in children. Subclinical dehydration refers to mild fluid loss that does not show obvious signs, such as extreme thirst, but still affects the body.

What are the symptoms of dehydration in children?

Dr Parikh stated that many children exhibit symptoms such as tiredness, irritability and poor appetite. They may also complain of headaches, feel dizzy, or show reduced concentration while studying. Another important sign is decreased urination or darker urine, which often goes unnoticed. Over time, if not addressed, this mild dehydration can impact energy levels and mood, and may become severe, requiring hospital admission. Hence, parents must take charge of their child’s health and seek timely attention even for mild dehydration.

How can parents help children when they are dehydrated?

Dr Parikh shared some simple tips that can help beat dehydration in childre. The expert said that dehydration can be prevented in children by encouraging them to drink water regularly. Children should ideally consume at least 2–3 litres of water daily, along with coconut water, buttermilk and fresh fruit juices to stay hydrated. Parents can also include foods such as watermelon, oranges and cucumbers, which help maintain hydration. It is advisable to limit junk, oily, canned and processed foods. Children should avoid playing outdoors during peak heat hours. Parents should dress their children in light, loose cotton clothing, which helps reduce sweating. Monitoring urine colour and frequency can be a simple way to assess a child’s hydration status. Parents should adhere to these tips to prevent dehydration in children.

Do you see your elderly loved ones pausing and quietly struggling every time they eat? In many households, a slight difficulty in swallowing—known as dysphagia—is often brushed aside as normal ageing or eating too fast.

Speaking to HealthandMe, doctors warned that this seemingly harmless symptom should not be ignored, as it could be cancer of the esophagus.

"When food repeatedly feels stuck in the chest, or swallowing becomes difficult, it may not be ageing at all. It could be an early warning sign of a serious condition, including esophageal cancer," said Dr. Surender Kumar Dabas, Chairman - Manipal Comprehensive Cancer Centre and Onco Robotic Surgeries, Manipal Hospital.

Esophageal cancer is a growth of cells that starts in the esophagus. The esophagus is a long, hollow tube that helps move swallowed food from the back of the throat to the stomach for digestion.

"Esophageal cancer typically remains silent during its initial phases, and the inability to swallow is one of the most typical warning signs. With the expansion of the tumor, the food pipe has the potential to get narrowed, which obstructs the smooth passage of food into the stomach. In case an individual constantly feels that something gets stuck in the mouth, one has to see a doctor and have a proper examination," added Dr. Hemkant Verma, Consultant - Surgical Oncology, ShardaCare-Healthcity.

Warning Signs That Many Ignore

Also read:This Man Made 24 Doctor Visits for Back and Leg Pain, Died 12 Days After Cancer Diagnosis

Although difficulty swallowing is usually the first sign people notice, the body sends out other quite signals too. This includes:

• Food sticking in the chest or throat: A sensation that food is not going down smoothly and feels stuck after swallowing, especially with solid foods.

• Gradual difficulty in swallowing: Initially struggling with solids like roti or rice, and gradually facing difficulty even with semi-solids or liquids.

• Frequent choking or coughing while eating: This may indicate that food is entering the airway instead of the esophagus

• Unintentional weight loss: Dropping weight without even trying, mostly because eating has started to feel like a difficult chore.

• Chest pain: A persistent discomfort behind the breastbone that is not relieved with an antacid

• Vomiting or coughing up blood: A serious sign that the lining of the food pipe is irritated or damaged and needs immediate attention.

Treatment For Esophageal Cancer

Esophageal cancer is a malignant tumor in the food pipe, and primarily affects people over the age of 55.

The doctors also warned of lifestyle choices that may predispose one to esophageal cancer. This includes tobacco use, alcohol consumption, chronic acid reflux, obesity, and bad diet choices.

While early diagnosis is quite important to enhance the success of treatment, patients often tend to postpone seeking medical treatment for such symptoms, resulting in late diagnosis and poor outcomes.

Read more: Suffering From Mid-back Pain? Doctors Say It May Be Spinal TB

The first step in diagnosis is usually an endoscopy, where a camera is used to check for any unusual growths. If a tumor is found, a biopsy is taken.

Upon biopsy confirmation, a staging workup is required, usually in the form of a PET-CT scan.

Treatment typically involves a multidisciplinary approach consisting of radiation and chemotherapy followed by surgery. The surgery is known as esophagectomy, where the diseased part of the tube is removed, and the remaining part is reconnected to the stomach. If detected early and treated properly, the disease is curable.