According to a study published in the November 6, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology, older people who are sleepy during the day or lose interest in activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia.
People with the syndrome walk slowly and report memory problems, but they do not have a mobility handicap or dementia. Motoric cognitive risk syndrome is a condition that can develop before dementia.
The study found that people with excessive daytime sleepiness and a lack of enthusiasm to get things done were more likely to develop the syndrome than people without those sleep-related issues. The study does not prove that these sleep-related issues cause the syndrome, it only shows an association.
“Our findings emphasize the need for screening for sleep issues,” said study author Victoire Leroy, MD, PhD, of Albert Einstein College of Medicine in the Bronx, New York. “There’s potential that people could get help with their sleep issues and prevent cognitive decline later in life.”
The study included 445 participants, with an average age of 76, who did not have dementia. Participants completed sleep surveys at the beginning of the trial. They were queried about memory problems, and their walking pace was measured on a treadmill at the beginning of the study and then once a year for the next three years.
The sleep assessment included questions about how frequently people had difficulties sleeping because they woke up in the middle of the night, couldn't fall asleep within 30 minutes, or felt too hot or cold, as well as whether they used sleep aids. The question to assess excessive daytime drowsiness asks how frequently people have had problems remaining awake when driving, eating meals, or were engaged in any other activity.
In total, 177 participants fit the category of bad sleepers, whereas 268 satisfied the definition of good sleepers.
At the outset of the trial, 42 participants had motoric cognitive risk syndrome. Throughout the trial, 36 more persons got the condition.
35.5% of patients who experienced extreme daytime sleepiness and a lack of enthusiasm developed the syndrome, compared to 6.7% who did not. After accounting for other factors that could influence the risk of the syndrome, such as age, depression, and other health conditions, researchers discovered that people with excessive daytime sleepiness and a lack of enthusiasm were more than three times more likely to develop the syndrome than those who did not have those sleep-related issues.
“More research needs to be done to look at the relationship between sleep issues and cognitive decline and the role played by motoric cognitive risk syndrome,” Leroy said. “We also need studies to explain the mechanisms that link these sleep disturbances to motoric cognitive risk syndrome and cognitive decline.”
A limitation of the study is that participants reported their own sleep information, so they may not have remembered everything accurately.
The study was supported by the National Institute on Aging.
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Hundreds of thousands of children are set to receive an additional vaccine under the NHS routine childhood immunisation programme. Health officials have confirmed it will be given alongside the existing MMR jab, which protects children in England against measles, mumps and rubella.
The decision follows advice from the Joint Committee on Vaccination and Immunisation and will see the current MMR jab replaced with a combined MMRV vaccine. This single injection protects against measles, mumps, rubella and chickenpox. Studies estimate that chickenpox in childhood leads to around £24 million a year in lost earnings and productivity across the UK. Alongside reducing this impact, the rollout is expected to save the NHS about £15 million each year in treatment costs linked to the illness.
Dr Claire Fuller, National Medical Director for NHS England, said: “This marks a very positive step for children and families, offering protection against chickenpox for the first time and strengthening the range of routine vaccinations we already give to help shield children from serious diseases.
“From now on, the combined vaccine covering measles, mumps, rubella and chickenpox will be offered at children’s routine vaccination appointments. This will help keep children healthier, prevent illness caused by these highly infectious viruses, and support the NHS shift from treating sickness to preventing it, while keeping more children safe and in school.”
Recent figures show that around half of children will have chickenpox by the age of four, with nine in ten catching it before they turn ten. Children who develop chickenpox are usually advised to stay away from school until all spots have crusted over, which typically happens about five days after the rash appears.
With the new vaccine in place, fewer children are expected to miss time at nursery or school. This should also reduce the amount of work parents need to take off to look after them.
Protection against chickenpox is being offered through a new combined vaccine known as MMRV, which replaces the existing MMR jab. The MMRV vaccine protects against measles, mumps, rubella and varicella, the virus that causes chickenpox.
Specialists say adding the varicella vaccine to the NHS childhood immunisation schedule will significantly cut the number of people who get chickenpox, resulting in far fewer severe cases.
While the vaccine does not guarantee lifelong immunity, it greatly lowers the chances of catching chickenpox or developing a serious form of the illness. Serious side effects, including severe allergic reactions, are extremely uncommon.
The vaccine is a live vaccine, meaning it contains a weakened form of the chickenpox virus. Because of this, it is not recommended for people with weakened immune systems due to conditions such as HIV or treatments like chemotherapy.
The change brings the UK in line with countries that already include routine chickenpox vaccination, such as Germany, Canada, Australia and the United States.
In the past, there were concerns that vaccinating children against chickenpox could lead to an increase in shingles later in life, but a large long-term study from the US has since shown this is not the case.
The Joint Committee on Vaccination and Immunisation, which advises the government, recommended the introduction of the MMRV vaccine for all children in November 2023.
The government confirmed plans to roll out the MMRV vaccine in August 2025, after new figures showed that none of England’s main childhood vaccinations reached the 95 percent uptake target in 2024 to 2025.
According to the UK Health Security Agency, 91.9 percent of five-year-olds had received one dose of the MMR vaccine. This figure was unchanged from 2023 to 2024 and remains the lowest level recorded since 2010 to 2011.
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Running to the bathroom with vomiting, diarrhea, or both is never fun. Yet “stomach bugs” are a common part of life, and norovirus is often behind these outbreaks.
Norovirus is a highly contagious virus that triggers symptoms like vomiting and diarrhea, and cases are climbing this winter. While it often makes headlines during cruise ship outbreaks, most infections occur on land, anyone can catch it.
“Originally called ‘winter vomiting disease,’ norovirus is one of the leading causes of vomiting and diarrhea in both children and adults,” explains Dr. Ava Anklesaria, a gastroenterologist at Columbia who treats multiple cases each year. “The virus is very stable in the environment, and only a tiny amount is needed to infect someone, which makes it easy to spread. Simple measures like washing your hands with soap and water for 20 seconds and avoiding contact with sick individuals can prevent infection.”
In the U.S., the CDC estimates that norovirus causes about 21 million illnesses, 465,000 emergency visits—mostly among children—and around 900 deaths annually.
Norovirus causes viral gastroenteritis, sometimes called “stomach flu” or a “stomach bug,” though it isn’t related to influenza. As per Mayo Clinic, it consists of several strains of RNA viruses that inflame the stomach and intestines, causing nausea, vomiting, and diarrhea.
Symptoms usually appear one to two days after exposure and often include:
Most people recover within one to three days, though they can still spread the virus for up to two weeks after feeling better.
Anyone can get infected. Norovirus is the leading cause of acute gastroenteritis in the U.S., affecting all ages. Young children, older adults, pregnant people, and individuals with existing health conditions are more vulnerable.
Norovirus spreads very easily. It survives well in the environment, and only a minuscule amount is enough to infect someone. In fact, just a few particles on the head of a pin can infect over 1,000 people.
Exposure can happen through:
As per the National Institute Of Health, once inside the body, norovirus targets the stomach and intestines. It inflames the lining of the gut, which disrupts normal digestion and absorption. This inflammation leads to increased fluid secretion and faster movement through the intestines, causing watery diarrhea. Vomiting occurs as the stomach reacts to the irritation.
The gut lining may also temporarily lose some of its ability to absorb nutrients and fluids, which can lead to dehydration, electrolyte imbalances, and fatigue. While symptoms usually resolve in a few days, the virus can continue to be shed in stool for up to two weeks, meaning the gut can remain a source of infection even after recovery.
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Atenolol is widely prescribed for conditions such as high blood pressure and irregular heart rhythms. While it is suitable for many adults, some people need to be especially careful before starting the beta-blocker.
NHS guidance highlights that certain medical conditions and life stages mean a doctor should be consulted first. This includes people with low blood pressure, Raynaud’s phenomenon, or asthma, among others.
The NHS advises speaking to a doctor before taking atenolol if you fall into any of the following groups:
According to official NHS advice, atenolol works by slowing the heart rate, which helps the heart pump blood around the body more easily. In addition to treating blood pressure and heart rhythm problems, it is sometimes prescribed to help prevent migraines and ease symptoms of anxiety.
The NHS notes: “Atenolol is only available on prescription. It comes as tablets or a liquid that you swallow. It can also be given by injection, but this is usually only done in hospital.”
People who take other medicines should also check with a doctor before starting atenolol, as some drugs can affect how well it works or increase the risk of side effects. This applies not only to prescription medicines but also to herbal remedies, vitamins, and supplements.
You should speak to a doctor if you take:
The NHS also states: “There’s not enough information to say that herbal remedies and supplements are safe to take with atenolol. They’re not tested in the same way as pharmacy and prescription medicines, and they’re generally not tested for how they affect other medicines.”
The dose of atenolol you need depends on the condition being treated. For high blood pressure, the usual adult dose is between 25mg and 50mg once a day, but you should always follow your doctor’s instructions. Your medication packaging will also provide guidance on how to take it.
How long you stay on atenolol varies as well. For long-term conditions such as high blood pressure, it is often taken for many years and, in some cases, for life.
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