According to a study published in the November 6, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology, older people who are sleepy during the day or lose interest in activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia.
People with the syndrome walk slowly and report memory problems, but they do not have a mobility handicap or dementia. Motoric cognitive risk syndrome is a condition that can develop before dementia.
The study found that people with excessive daytime sleepiness and a lack of enthusiasm to get things done were more likely to develop the syndrome than people without those sleep-related issues. The study does not prove that these sleep-related issues cause the syndrome, it only shows an association.
“Our findings emphasize the need for screening for sleep issues,” said study author Victoire Leroy, MD, PhD, of Albert Einstein College of Medicine in the Bronx, New York. “There’s potential that people could get help with their sleep issues and prevent cognitive decline later in life.”
The study included 445 participants, with an average age of 76, who did not have dementia. Participants completed sleep surveys at the beginning of the trial. They were queried about memory problems, and their walking pace was measured on a treadmill at the beginning of the study and then once a year for the next three years.
The sleep assessment included questions about how frequently people had difficulties sleeping because they woke up in the middle of the night, couldn't fall asleep within 30 minutes, or felt too hot or cold, as well as whether they used sleep aids. The question to assess excessive daytime drowsiness asks how frequently people have had problems remaining awake when driving, eating meals, or were engaged in any other activity.
In total, 177 participants fit the category of bad sleepers, whereas 268 satisfied the definition of good sleepers.
At the outset of the trial, 42 participants had motoric cognitive risk syndrome. Throughout the trial, 36 more persons got the condition.
35.5% of patients who experienced extreme daytime sleepiness and a lack of enthusiasm developed the syndrome, compared to 6.7% who did not. After accounting for other factors that could influence the risk of the syndrome, such as age, depression, and other health conditions, researchers discovered that people with excessive daytime sleepiness and a lack of enthusiasm were more than three times more likely to develop the syndrome than those who did not have those sleep-related issues.
“More research needs to be done to look at the relationship between sleep issues and cognitive decline and the role played by motoric cognitive risk syndrome,” Leroy said. “We also need studies to explain the mechanisms that link these sleep disturbances to motoric cognitive risk syndrome and cognitive decline.”
A limitation of the study is that participants reported their own sleep information, so they may not have remembered everything accurately.
The study was supported by the National Institute on Aging.
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In 2025, Andhra Pradesh reported 1,566 scrub typhus cases, and nine suspected deaths, according to data from the Integrated Health Information Platform, Integrated Disease Surveillance Programme (IDSP-IHIP) on 8 December. Followed by Karnataka with 1,870 cases, Tamil Nadu 7,308 cases, and Telangana, 309 cases. Scrub typhus cases have significantly increased from previous year. It is one of the deadliest infections affecting multiple organs, or even death. Early it was relevant to poeple working in fields, new studies show it migrating to human settlements.
Scrub typhus, also known as bush typhus, is a bacterial infection caused by bacteria infection, caused by bacterium Orientia tsutsugamushi. It is spread through bites of infected larval mites, Chiggers.
Most cases of scrub typhus occur in rural areas of Southeast Asia, Indonesia, China, Japan, the Indian subcontinent and northern Australia. Until now, it was believed that chiggers only lurked in the tall grasses of remote paddy fields or dense forests. Due to this, it is commonly known as "farmers' disease", only confined to the fields.
However, new PLOS study data revealed the opposite. The study is led by researchers from Christian Medical College (CMC) Vellore and international collaborators and suggests that the bulk of infections are now even occurring within human settlements.
The study monitored over 32 000 people in Tamil Nadu, which led to the conclusion that agricultural activities, long considered the primary risk factor, were only weakly associated with the disease in high-prevalence areas.
Risk for scrub typhus is significantly higher for those living in clustered houses or homes with fewer rooms. If the micro environment around the residence is unmaintained, gardens are patched, or even the damp corners of a courtyard, it could lead to breeding ground for the mites and the rodents that carry Chiggers.
It was once believed that working-age men were the most affected, but the new study tells otherwise. According to the new data, women over 60 are at the highest risk of infection.
As women spend most of their time in and around the home, due to household work, from the kitchen to the laundry, these activities are now the primary cross point of contact with infected mites.
As initial symptoms of infection, such as fever, headache, and muscle pain, are the same as viral flu or dengue, many first seek help from untrained practitioners or local pharmacies.
By the time they reach the hospital, the disease has already progressed to severe complications like acute respiratory distress syndrome (ARDS), Kidney failure, or Meningoencephalitis, which is inflammation of your meninges and brain at the same time, a life-threatening condition.
Not only this, the researchers revealed that nearly 10 percent of affected households exceed 25 percent of their income in the treatment.
For severe cases, the cost of treatment can be up to approximately INR 110,000, a staggering sum for rural and peri-urban families earning a fraction of that monthly.
Early intervention is necessary, as if a fever lasts more than two days, don't just treat it as "seasonal fever".
Consult a qualified doctor and specifically ask about scrub typhus. Infection can be treated with doxycycline common antibiotic, in the early stages. The case fatality rate in this study was 1.5 percent, hospital based studies in South India have previously recorded mortality rates as high 30 percent when treatment is delayed
Credit: Canva
Shingles, caused by the reactivation of the varicella-zoster virus (the same virus that causes chickenpox), can strike more than once, especially in older adults and people with weakened immune systems. Vaccination against the virus is the most effective way to prevent shingles and related complications, said health experts as part of the Shingles Awareness Week.
The World Health Organization estimates that over 90 percent of individuals worldwide are infected with the varicella-zoster virus, indicating a high susceptibility to shingles.
Health experts explained that the varicella-zoster virus remains dormant in the nerves of the body after an attack of chickenpox.
Dr. Monica Mahajan, Senior Director – Internal Medicine, Max Multi Speciality Centre, Panchsheel Park, told HealthandMe that the virus can remain in an inactive state for two to five decades, or even longer.
When the immunity decreases, the virus can re-activate to cause shingles. The most common symptoms include a rash with sharp, shooting, or stabbing nerve pain.
While it is rare, shingles can recur as one episode of the disease doesn’t grant lifelong immunity.
“It is possible to get shingles infection more than once. An episode of shingles may not give lifelong immunity to the disease. Although it is a rare occurrence, people who have had shingles once can get it again. But those who get vaccinated after the first attack of shingles can prevent the second attack,” Dr. Mahajan said.
The common manifestation of shingles is a painful blister-like rash, which usually occurs only on one side of the body or face.
It is followed by post-herpetic neuralgia -- a nerve pain that arises in the areas where the rash was located, which often lasts for months or years after the rash has cleared up.
“It is severe and excruciating and is sometimes described as a pain that is worse than chronic cancer pain,” Dr. Chandani Jain Gupta, Dermatologist & Aesthetic Physician, Elantis Healthcare, New Delhi, told HealthandMe.
Dr. Gupta noted that shingles can also affect the eye, impacting the patient's ability to see.
Other less frequent complications of shingles are secondary bacterial infections of the rash, pneumonia, blindness, hearing loss, and neurological complications involving the brain. Fatigue, fever, and sensitivity to touch are other potential complications due to shingles.
As longevity increases, the phenomenon of ‘immunosenescence’ becomes more common. This means that as we age, our immunity declines, and this process generally starts at the age of 50 years.
"As life expectancy is increasing, more and more people live well beyond the age of 50 years. These people have lowered immunity and are at a higher risk of developing shingles," Dr. Mahajan said.
People who suffer from conditions such as diabetes, HIV, cancer, and patients with kidney or liver transplants are also at a higher risk of shingles because of lower immunity.
Patients who are on certain drugs called the ‘immunomodulators’ (used for conditions like arthritis, lupus, and some skin diseases) that reduce immunity are also more vulnerable to shingles.
While some anti-viral medicines can reduce the intensity of the rash and the pain, these are effective only when given within three days of the first symptom. Despite medications, the outcome is not satisfactory in most patients.
But shingles can be prevented with vaccination.
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A now-viral video has revealed how a new mother who believed she had grown excessive fat tissue instead discovered that her body had developed a third nipple under her armpit.
Jasmine, an American woman had given birth five days earlier when a lactation consultant visited her to giver her advice on breastfeeding. The new mother, who was still exhausted and recovering from childbirth, recalled mentioning that her armpits always carried what she believed was excess fat that darkened during pregnancy.
"I breastfed my first baby for one-and-a-half-years, so I'm thinking that there's nothing this nurse can say that's going to surprise me," Jasmine said.
However, after a careful examination, the expert told her that the swelling in her underarm was extra breast tissue and that she also had "a nipple” there.
"When you're pregnant, your nipples and areolas will get really dark, and I have noticed the same change with my armpits, so I was like 'Great! extra breast tissue, I already knew that.' And then the lactation consultant is like 'Let me see,' and I show her, and she goes, 'Oh! yeah... And that's a nipple'.
"You know how cows and puppies and kittens, they have that line of nipples? Yeah, humans have that, too. Tell me why she's telling me about someone that had an extra nipple on her thigh. Telling me I have a third nipple in my armpit before I even had my first postpartum poop is diabolical work,” she said, joking about how little sleep she’d had.
According to Dr Rooma Sinha, an obstetrician and gynaecologist at Apollo Hospitals in Hyderabad, Jasmine's third nipple is known as the axillary tail of the breast, a normal extension of breast glandular tissue that tapers into the underarm.
“Some women have axillary tail of the breast. This is probably that. It may produce milk if it has active mammary glands," she told Moneycontrol .
She also confirmed that humans can have supernumerary nipples along what is known as the “embryonic milk line,” extending from the armpit toward the chest. However, this line does not extend down to the thigh, as Jasmine recalled in her video.
According to experts, the axillary tail can feel like a lump or thickened area, particularly during hormonal changes such as pregnancy, breastfeeding or menstruation and may become tender or enlarged.
“Regular breast production is sufficient for me,” she said, noting that the extra tissue was painful and that she might consider surgically removing the tissue after she decides not to have more children.
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