Could Ovarian Tissue Freezing Be More Beneficial Than Egg Freezing?

Updated Apr 17, 2025 | 06:00 AM IST

Could Ovarian Tissue Freezing Be More Beneficial Than Egg Freezing?

SummaryOvarian tissue freezing has led to 84 births from 309 procedures, restored fertility in two-thirds of women, and is up to 50% cheaper than egg freezing—with the added benefit of hormone restoration.

For years, egg freezing has dominated the conversation around fertility preservation. However, a growing number of reproductive specialists now believe that ovarian tissue freezing—an outpatient surgical procedure that involves removing and preserving a portion of a woman’s ovarian tissue—could be a superior alternative, particularly for younger women or those undergoing medical treatments like chemotherapy.

Unlike egg freezing, which requires hormonal stimulation over several weeks, ovarian tissue freezing can be completed quickly, even in children who haven’t yet reached puberty. And new data is backing up its promise: a recent review revealed that approximately 4 out of 10 women who underwent this procedure successfully gave birth later in life.

What Is Ovarian Tissue Freezing?

Ovarian tissue freezing, also known as ovarian tissue cryopreservation, involves surgically removing a portion of one ovary—typically through a minimally invasive laparoscopic procedure—and preserving its outer shell, where thousands of immature eggs reside. This tissue is sliced into thin slivers and stored in a programmable freezer using a Slow Freezing technique that can take up to six meticulous hours in the lab.

Once the woman is ready to conceive, the tissue can be thawed and transplanted back into her body—either in the pelvis or under the skin. If successful, this transplant can restore hormonal function, trigger menstruation, and even reverse menopausal symptoms in many women.

Egg Freezing vs. Ovarian Tissue Freezing: What’s the Difference?

The numbers are compelling. A study conducted by Dr. Kutluk Oktay—who first performed the procedure in 1999—and Dr. Fernanda Pacheco reviewed data from 1999 to 2016. They found that out of 309 ovarian tissue freezing cases, 84 births were recorded, and two-thirds of patients experienced a restoration of reproductive or hormonal function.

One particularly noteworthy aspect: only about one-third of patients required IVF, while the rest were able to conceive naturally—something not possible with frozen eggs. The tissue appears to create a more natural ovarian environment, increasing the chance of spontaneous conception.

Initially developed as a fertility-preserving option for cancer patients, especially children who cannot undergo egg retrieval, ovarian tissue freezing is increasingly being considered for healthy women wanting to delay childbirth. According to Dr. Oktay, the procedure’s ability to reverse menopause, preserve hormonal function, and restore natural fertility makes it a holistic approach to reproductive longevity.

In fact, many women undergo ovarian tissue freezing when there’s insufficient time for ovarian stimulation or when the ovaries are at risk of being damaged by cancer treatment. Unlike egg retrieval, which can delay urgent therapies, this method provides a faster and potentially more versatile solution.

Egg freezing typically yields about 10 to 15 eggs per cycle. In contrast, a single procedure of ovarian tissue extraction can preserve hundreds or even thousands of eggs in their immature form, providing a much larger reservoir of fertility potential. This makes the procedure more cost-effective in the long run and potentially reduces the number of interventions a woman might need.

Moreover, with ovarian tissue, there’s no need for the hormonal stimulation that egg freezing requires—saving both time and the physical side effects that some women experience.

How Does the Transplant Work?

Once a woman is ready to conceive, the frozen tissue can be thawed and transplanted using two primary techniques developed by Dr. Oktay:

Pelvic Transplantation: Here, tissue is grafted near the remaining ovary or on the pelvic wall using a biodegradable scaffold. It reconnects with the surrounding blood vessels over 2–10 days, though some egg loss (over 50%) can occur during this period.

Heterotopic (Under-the-Skin) Transplantation: This is used when the pelvis isn’t viable due to radiation or scarring. It’s performed under local anesthesia in the IVF lab—making it less invasive—but it does require IVF for conception.

So far, about 20 live births have been recorded from pelvic ovarian transplants. Under-the-skin grafts are still in their experimental phase, though promising embryo development has been reported.

Is Ovarian Tissue Freezing Affordable?

Fertility preservation isn’t cheap. However, ovarian tissue freezing may offer more value for money. Ovarian tissue freezing costs approximately $10,000, while egg freezing can run upwards of $20,000 or more depending on the number of cycles needed.

Given that a single ovarian tissue extraction can preserve significantly more eggs than traditional retrieval, this newer method may also reduce the long-term financial burden for women who may need multiple rounds of egg retrieval.

Can You Conceive Naturally After a Transplant?

Yes, but with caution. After pelvic transplantation, women can conceive naturally if their fallopian tubes are intact and functional. However, since transplanted ovaries may not last as long as natural ones, doctors often recommend IVF to speed up conception and avoid exhausting the finite egg supply in the graft.

While ovarian tissue freezing is still technically considered experimental, the clinical data and real-world success stories are making it a strong contender in fertility preservation. Its ability to not only safeguard fertility but also reverse menopause, restore hormonal balance, and offer natural pregnancy potential makes it far more than just an alternative to egg freezing, it could be the future of reproductive medicine.

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Updated Apr 19, 2025 | 05:16 PM IST

Amid Conflicting Bird Flu Reports, Parents Are Struggling To Find Reliable Information For Kids Safety

SummaryThe flu season and the various strains that have come up in the past few months have stretched people thin with worries and concern. Parents especially have been dealing with a tough time trying to keep their families safe and a new survey reveals a startling truth.

As bird flu progresses in US, parents along with other concerned citizens of the country are scrambling to get information about it. Centers of Disease Control and Prevention (CDC) explains that while the current risk is low, they are working towards bettering the situation with the help of state and monitoring people with animal exposure.

It's hard for parents to know what's really going on with bird flu. A recent survey done by University of Michigan Health C.S. Mott Children's Hospital National Poll on Children's Health showed that many parents just can't find good, trustworthy information. Parents don't know who to believe or where to look which makes them feel worried and unsure about how to keep their families safe. It is important to know the real facts, but it's tough when they find varied reports everywhere. Some parents think the news is making it sound worse than it is, while others are concerned that not enough is being done.

What Are Parents Concerned About?

Many parents are feeling lost when trying to find information about bird flu. They see different stories online and on TV, and they don't know what's true. This makes them worry because they want to protect their kids. Parents mostly rely on news reports (78%) for information, while others use social media is also a common source (31%). The rest turn to the internet (19%), family and friends (15%), government agencies (11%) and health care providers (11%) .

Parents are worried about bird flu spreading to people. They're scared that animals could give it to humans, or that people could give it to each other. They're also not sure if the government can handle a big outbreak. They don't have much confidence that the government can get rid of infected animals or food. They're also worried that they won't get clear information about recalls or how to get rid of dangerous products. They just want to feel like someone is in control.

The survey also revealed that one-third of the parents took action to protect their family against the bird flu, while 22% were being more careful about the hygiene. Of them, 13% were cautious handling eggs, chicken and other meat products, 12% avoid contact with birds, and 10% avoided raw milk.

Flu viruses can infect chicken eggs by entering through the eggshell. The eggshells are smaller than the pores of eggshells, which means viruses can enter the eggs and the egg's surface will still be protected. However, it is still important to handle it safely.

As per the US Food and Drug Administration, cooking poultry, eggs and other animal products to the proper temperature and preventing cross-contamination between raw and cooked food.

Symptoms of Bird Flu to Watch for

  • Pink eye
  • fever
  • fatigue
  • cough
  • muscle aches
  • sore throat
  • nausea
  • vomiting
  • diarrhea
  • study or runny nose
  • shortness of breath

What Can Parents Do?

To feel safer, some parents are changing their habits. They're being extra careful about washing their hands and keeping things clean. Some are also being more careful when handling chicken and eggs, making sure they're cooked properly. Some parents are even avoiding contact with birds and wild animals, just to be safe. They're also being cautious about drinking raw milk and are eating less chicken and eggs. They are trying to be proactive.

The survey revealed that parents don't feel like they can trust the government's response to bird flu. This lack of trust makes them even more worried. When people don't know what's happening, they get scared. It's important for health officials to be open and honest about what they're doing to stop the spread of the virus. They need to give clear information about how to stay safe with food. This will help parents feel more calm and confident.

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Chinese Shop Offers 'Placenta Processing', Sells Capsules Made After Birth

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Updated Apr 19, 2025 | 02:12 PM IST

Chinese Shop Offers 'Placenta Processing', Sells Capsules Made After Birth

SummaryImages shared on social media revealed a signboard outside the store clearly stating "placenta processing."

A snack shop in southeastern China has come under fire after allegedly advertising "placenta processing" services and selling capsules made from afterbirth. The incident, which surfaced on April 6, has triggered widespread criticism and prompted an official investigation.

The controversy began when a netizen posted online about Auntie Congee’s Snack Shop, located near the Changzhou Hospital of Traditional Chinese Medicine in Jiangsu province. According to the post, the shop was involved in the processing of human placentas and selling them in capsule form, claiming health-boosting properties.

Images shared on social media revealed a signboard outside the store clearly stating “placenta processing.” The shop reportedly charged 800 yuan (US$110) if the customer did not provide their own placenta, and 300 yuan if they did. The business claimed that all placentas used were obtained from new mothers in hospitals.

The owner, who previously worked in post-partum recovery, told local media that she could also connect customers with maternity matrons. Alongside the physical snack shop, she also operated an online store named Zixuan Maternity Matron Centre.

The online platform offered various post-partum services, including maternity care, childcare, meal preparation for new mothers, placenta processing, and recovery services. Promotional materials showed the process of grinding placentas with ingredients such as ginseng powder and turning the mixture into capsules, which were labelled *ziheche*, the term used in traditional Chinese medicine for placenta.

A poster advertising the shop highlighted the supposed benefits of consuming placenta, noting it is rich in protein and nutrients. It also mentioned two processing techniques—patented freezing and traditional methods—offering customers the option to observe the process in person.

The Shop Has Been Shut Down For Rectification

On April 8, the Changzhou Municipal Health Commission informed Jimu News that the shop had been shut down for rectification. A commission staff member stated, “We are currently investigating the source of the placentas. Preliminary findings indicate that they did not come from any hospital.”

In traditional Chinese medicine (TCM), the use of placenta has long been believed to help replenish energy and nourish the blood. It is sometimes recommended for individuals experiencing fatigue, chronic coughing, or infertility. However, citing ethical and safety concerns, the Chinese Pharmacopoeia delisted placenta as an approved medicinal ingredient in 2015.

Under Chinese law, placentas are considered the personal property of the post-partum mother, who alone can decide how they are disposed of. The sale of placentas by individuals or organisations remains illegal.

The case, initially reported by the Yangtze Evening News, has sparked outrage online. One user remarked, “I really cannot believe there are people who eat placenta as food. It is so disgusting.” Another added, “It is already the year 2025! Who even believes in such nonsense? And treating women as some kind of ‘superfood’—is that not objectifying women?” A third person said, “This is not surprising at all. In the past, hospitals would ask mothers whether they wanted to keep their placentas. If they did, it was usually consumed as food.”

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8 Reasons Why Your Eyes May Itch

Credits: Canva

Updated Apr 19, 2025 | 01:00 PM IST

8 Reasons Why You May Have An Itchy Eye

SummaryThere could be many reasons for someone to get an itchy eyes. How would you know what is causing your eye to itch? Read on to know.

People can have itchy eyes for various reasons. The reasons may include allergies, environmental pollutants, infection, and some conditions that can affect the eyes. The treatments could vary from home remedies to medical intervention.

Seasonal Allergies

If you have itchy eyes around the same time in the year, you may have seasonal allergies. You could be allergic to ragweed or something else that blooms during the season, releases pollen and gets into your eyes that time of the year.

You may also get reactions like sneezing and nasal congestion. Allergic symptoms are also triggered by histamine, which is a compound released by cells to defend against allergens. It causes an inflammatory response, and itchy eyes are one of the common signs of it.

So, what can you do?

  • Pay attention to the local weather reports, look out for pollens.
  • Keep your doors and windows locked.
  • Take showers and wash clothes to keep pollen away.
  • Wear a mask every time you stay outside.

To counter your allergies, you can also use over-the-counter astihismine medications, which can be helpful for controlling symptoms.

Perennial Allergies

They are not like seasonal allergies, they are the ones that stay year-long. Things like mold, dust, and pet dander could be the reason that can trigger perennial eye allergies.

You might be allergic to certain products around your home. Your contact lens solution could be bothering your eyes, or even your soap or shampoo might be the cause.

If you've already ruled out environmental allergens, try stopping the use of any product that comes into contact with your eyes. It may take some trial and error, but finding the source can make a big difference.

To know for sure if you have an allergy, an allergist can do a skin test. This involves putting small amounts of allergens—like ragweed or pet dander—just under your skin to check for a reaction. These tests are generally safe for both kids and adults.

Along with avoiding allergens, medications like antihistamines or corticosteroids can help reduce eye inflammation and discomfort.

Airborne Irritants

There could be people who are sensitive to smoke, diesel exhaust, or even certain perfumes. You could use soothing eye drops to cool the irritation.

Infection

Eye infections could come from viral, bacterial, and fungal infections. These all can make your eye itchy. One of the common infections is conjunctivitis, also known as pink eyes. It is very contagious and could be accompanied by drainage from the affected eye.

Other infections could be uveitis, which is an inflammation to the iris. Steroids may also help with this. The best way to deal with it is to see a doctor and get the right help.

Dry Eye

There could be a lot of reasons that can cause a dry eye. This happens when your tears dry out, which are made from combination of water, oil, and mucus to keep your eyes moist.

Diabetes could be the reason for dry eyes. Sometimes, a blocked tear duct or tear gland leads to dry and itchy eyes. Other reasons which may contribute to dry eyes are:

  • antidepressants
  • medications that lower blood pressure
  • birth control pills
  • decongestants

Eyestrain

If you look at your computer screens for a little too long, or try to read something in a poorly lit area, it can strain your eyes and they could feel very itchy and dry. In fact, driving for a long time, especially at night could also strain your eyes. It can also feel itchy, if it is too sunny.

Overusing Contact Lenses

Contact lenses also have to be used for a limited time period. If you have worn your contact lenses for too long, or have not replaced it, or washed them regularly, it can itch your eyes.

Blepharitis

Red and itchy eyes can sometimes be caused by blepharitis—an inflammation of the eyelids. This happens when the tiny oil glands near the base of your eyelashes get blocked. Keeping your eyelids clean can often help ease symptoms like swelling and watery eyes.

While blepharitis usually doesn’t affect your vision, it can become a long-term issue and may lead to conjunctivitis or other eye problems. In some cases, antibiotics or anti-inflammatory medicines may be needed to manage it and prevent complications.

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