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Some days my brain is like a storm, thoughts moving faster than I can keep up. A small mistake becomes an catastrophe, an offhand remark becomes a soul-deep fear. I turn around and around, analyzing each word, every move, every potentiality. But then, I discovered recently this easy 20-second hack which was actually pretty straightforward but made a tremendous difference in the negative thinking. Quickly [sitting my hand on my heart and reminding myself, I am enough. Even just that small hesitation interrupts the madness. My breath slows, my shoulders ease, and for a moment, the hurricane calms. This practice over time has become my anchor, reminding me that I am not thoughts—I am so much more.
Researchers at the University of California, Berkeley, have discovered that it doesn't need to take long to practice self-compassion to be beneficial. The study, published in the Behaviour Research and Therapy journal, revealed that performing a 20-second self-compassion touch, such as putting a hand on your heart or belly, can greatly reduce levels of stress and anxiety.
According to psychology researcher Eli Susman, who co-authored the study, a group of 135 college students was asked to dedicate just 20 seconds a day to affirm themselves with kind and positive thoughts while engaging in a self-compassionate touch. The results were striking: those who consistently practiced this simple technique over a month experienced notable improvements in mood, self-compassion, and emotional resilience, while stress hormone levels decreased.
Why 20 Seconds of Self-Compassion Works
1. Decrease in Cortisol Levels
The stress hormone cortisol is the cause of much of the physical and emotional damage chronic stress inflicts on the body. The researchers discovered that a mere 20 seconds of self-compassionate touch resulted in a measurable drop in cortisol, allowing people to recover from stress more rapidly.
2. Better Emotional Well-Being
By practicing positive self-affirmation and empathetic touch, study participants reported greater emotional equanimity and reduced reactivity to stressful challenges.
3. A Simple, Accessible Practice
Unlike many conventional mindfulness practices that might demand lengthy meditation sessions, this micropractice requires only 20 seconds, rendering it simple to fit into daily activities, be it at home, the workplace, or even during public transport rides.
How to Practice Self-Compassionate Touch
This exercise is very easy and can be done anywhere. Here's how you can adapt it to your daily life:
Step 1: Recognize Your Emotions
Close your eyes and reflect on a recent experience that made you feel stressed, unworthy, or critical of yourself. Notice the sensations in your body as you reflect on this episode.
Step 2: Practice a Soothing Touch
Put one hand on your heart and the other on your belly. If this doesn't feel comfortable to you, you can experiment with other ways of self-compassionate touching, including:
Stroking the back of your neck
Rubbing a place on your palm with your thumb
Hugging yourself lightly by holding your arms in across your chest
Step 3: Breathe Deeply and Give Yourself Kindness
Take a slow, deep breath in. Feel the warmth and gentle pressure of your hands. As you exhale, focus on releasing tension. Now, in your mind, repeat self-compassionate affirmations such as:
“I am kind to myself.”
“I am not my mistakes.”
“I give myself room and comfort.”
“I celebrate my uniqueness.”
“I take this time to appreciate who I am.”
Step 4: Finish with a Sense of Gratitude
Open your eyes after 20 seconds and simply take a moment to admire yourself for taking the time to do this practice. You can repeat it as many times as you need throughout the day.
Susman calls this approach a "micropractice"—a tiny but effective habit that enhances mental health without taking up much time. These practices are based on classic mindfulness and meditation practices but are tailored to fit today's busy lives.
While the research was conducted with college students, the findings have applications for individuals of all ages. Whether you are a working professional with a packed schedule, a parent with numerous responsibilities, or an individual dealing with anxiety, adding a 20-second self-compassion exercise to your daily routine can be a convenient and effective method for managing stress and developing resilience.
Making It a Daily Habit
The secret to reaping the rewards of self-compassionate touch is consistency. Below are some ways to incorporate it into your daily life:
Begin your day by practicing self-compassion in bed before rising.
Utilize it as a fast tool during stressful situations at work or school.
Unwind by doing this micropractice before bedtime to relax.
May merely 20 seconds a day cause you to desist from spinning? The short answer, per the most up-to-date science, is that yes, it can. Micropractices for self-compassion provide a straightforward, research-supported means for lessening distress, enhancing emotional resilience, and cultivating a friendlier relationship with oneself.
In a world where stress and worry are escalating, this simple practice is a good reminder that simple, purposeful acts of care for ourselves have the ability to create tremendous transformations in our mindset. Why not give it a try for one month, you might find a surprising transformation.
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Non-alcoholic fatty liver disease (NAFLD) is the commonest non-communicable disease in Indian women, with a prevalence rate of 35%. Globally, 30% of the population is suffering from NAFLD, and this projection is expected to progress to 56%, in a similar range to diabetes and obesity.
In India, the high rate of NAFLD is driven by the adoption of a westernized lifestyle, associated comorbidities like diabetes, obesity & hypertension. Fatty liver is known to progress to cirrhosis (end-stage liver disease) or liver cancer (hepatocellular cancer) if left untreated, which affects the survival rates and implicates a poor prognosis.
Unfortunately, it’s a silent disease and often presents at an advanced stage, leading to serious complications.
Women tend to have different outcomes with fatty liver disease when compared to men. Women may have a higher risk of life secondary to NAFLD when compared with men of the same age group. Conditions like age of menarche (first menstrual period), menopause status, alteration in reproductive hormones, and sarcopenia (muscle loss) may affect the development of NAFLD. Hormonal issues like oestrogen deficiency and Polycystic Ovarian Disease (PCOD) increase the risk of developing NAFLD. Women with type 2 diabetes, obesity, and larger waist circumference (metabolic syndrome) are more prone to NAFLD.
Besides physiological and hormonal factors, there are social and cultural factors like limited autonomy for women, hierarchy based on earning potential, and poor literacy levels (especially in rural regions), which may create health neglect or gender bias towards women’s health, and conditions like NAFLD can go neglected or ignored.
The urban populace has its own share of modern problems like alcohol, smoking, and a sedentary lifestyle. Fatty liver is totally preventable and reversible if diagnosed at an early stage with simple lifestyle modifications. Studies show that a diet high in protein and low in carbohydrates, or a diet with fruits and vegetables and whole grains combined with exercise for 30 minutes a day and 5 days a week, can significantly reverse fatty liver and liver cell inflammation.
There are no gender-based guidelines to treat or prevent this problem. In general, reducing the cardiovascular and metabolic risk remains the cornerstone to treat NAFLD in both men and women.
Research shows that up to 10% weight loss can reduce liver scarring and inflammation, whereas between 5-10% weight loss can reduce liver fat significantly.
There is some evidence that suggests black coffee (without sugar), Vitamin E, and Omega-3 fatty acids help prevent and reverse NAFLD. Specific and early consultation with a specialist (e.g. cardiologist, endocrinologist, or a gynecologist) can control the morbidity and mortality around the problem. Fatty liver has reached an epidemic level problem and therefore needs mass screening & awareness programs.
Early diagnosis is key and can be achieved by simple USG of the liver or Fibro scan combined with simple blood tests, liver LFT’s (liver function tests). Unfortunately, there’s no pill to replace exercise or a healthy lifestyle; otherwise, it would have been a blockbuster medicine.
However, the good news is this deadly and silent disease has a simple and inexpensive solution: a healthy diet and plenty of exercise, which is accessible to all. There is also an urgent need to increase awareness in women on NAFLD and ways to combat it, so they can get access to life-saving treatment at the earliest.
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For decades, thalassemia has been synonymous with lifelong blood transfusions, frequent hospital visits, and the persistent risk of iron overload. For patients and families, it has largely meant managing a chronic condition rather than truly treating it. That narrative, however, is beginning to change.
The recent approval of oral drugs for thalassemia by the US Food and Drug Administration marks a historic milestone. These oral, disease-modifying pyruvate kinase activators improve anemia in adults with non-transfusion-dependent (NTDT) and transfusion-dependent (TDT) \(\alpha\)- or \(\beta\)-thalassemia. For now, they are approved in the US and Saudi Arabia for adults with thalassemia, with European review ongoing.
It is offering a fundamentally different approach, one that targets the disease at its biological core rather than simply managing its complications. Yet, as this new era unfolds, a critical question remains: are patients being diagnosed early enough to benefit from it?
A shift from supportive care to targeted therapy:
Until recently, thalassemia management has depended heavily on blood transfusions and iron chelation therapy. While these interventions are life-saving, they do not correct the underlying defect in red blood cell production. Over time, repeated transfusions can lead to complications affecting vital organs such as the heart, liver, and endocrine system.
Oral drugs, however, work by activating pyruvate kinase in red blood cells, improving energy (ATP) production, and enhancing red cell survival. In simple terms, it helps the body produce more functional and longer-lasting red blood cells, leading to an increase in hemoglobin levels, reduced transfusion requirements, and improved quality of life, particularly with respect to fatigue, one of the most debilitating symptoms of the disease. Oral therapy working across a broader disease spectrum marks a significant advance.
India bears one of the highest burdens of thalassemia globally, with an estimated 10,000–15,000 affected children born each year and a carrier frequency of approximately 3–4% in the general population. Despite this, a large number of cases remain undiagnosed or are diagnosed late, particularly in individuals with milder forms who may live for years with unexplained anemia.
Delayed diagnosis has far-reaching consequences. Patients may develop preventable complications, families miss opportunities for genetic counseling, and access to emerging therapies is delayed or entirely missed. In the era of precision medicine, such delays are no longer acceptable.
A major challenge in India is the frequent misdiagnosis of thalassemia as iron deficiency anemia, especially in primary care settings. Many patients receive repeated courses of iron supplementation without clinical improvement, while the underlying genetic disorder remains unrecognized.
Certain clinical clues should prompt further evaluation: persistent microcytic anemia unresponsive to iron therapy, a family history of anemia or transfusion dependence, and a disproportionately high red blood cell count relative to hemoglobin levels. Diagnostic confirmation is straightforward with hemoglobin analysis using HPLC or electrophoresis; however, these tests are not always utilized at the appropriate time.
The approval of oral drugs underscores a fundamental shift, from managing symptoms to modifying disease biology. However, these benefits are maximized when therapy is initiated early, before irreversible organ damage occurs, for which timely diagnosis is pivotal.
Thalassemia diagnosis begins with a complete blood count demonstrating microcytic anemia with low mean corpuscular volume and a relatively high red cell count. Peripheral smear findings include target cells and anisopoikilocytosis. Confirmation is achieved through hemoglobin analysis using HPLC or electrophoresis, which typically shows elevated HbA₂ in β-thalassemia trait. Molecular testing further identifies specific gene mutations, enabling definitive diagnosis and prenatal counseling.
Screening programs play a pivotal role. Carrier detection through HbA₂ estimation, premarital and antenatal screening, and cascade testing within families are essential strategies, particularly in high-prevalence populations like India.
The mutation spectrum in India is well characterized. The most common β-thalassemia mutation is IVS-I-5 (G→C), accounting for nearly half of cases, followed by IVS-I-1 (G→T), codon 41/42 deletion, codon 8/9 insertion, and the 619 bp deletion. In α-thalassemia, the –α³․⁷ deletion predominates. This knowledge allows for cost-effective targeted molecular screening.
For years, the central question in thalassemia was: how do we manage this disease?
Today, it is shifting to: how early can we treat it effectively? Oral drugs represent a major therapeutic advance; however, cost considerations, accessibility, and long-term real-world outcomes will influence their widespread adoption. Nevertheless, the direction is clear: thalassemia care is entering a transformative era. In modern medicine, early diagnosis is no longer just beneficial; it is truly transformative.
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While the confirmation of the Andes strain of hantavirus behind the outbreak aboard the cruise ship MV Hondius in the South Atlantic has raised significant concerns of human-to-human transmission, experts from the International Hantavirus Society, as well as the World Health Organization (WHO), stated that the situation does not raise the risk of a pandemic.
So far, eight cases have been reported, including three deaths. The WHO has also confirmed that six cases have tested positive for the Andes virus, which can spread from person to person, through PCR testing.
The International Hantavirus Society, in a statement, warned that the virus differs significantly from most other hantaviruses because it can spread between people.
Founded in 2001, the Hantavirus Society is a global organization of scientists, clinicians, and researchers focused on studying hantaviruses, including their ecology, pathogenesis, and prevention.
“The virus on board the MV Hondius is the Andes strain of hantavirus. It is serious,” said the WHO chief Tedros Adhanom Ghebreyesus, in an open statement on the social media platform X.
However, the WHO and the members of the Hantavirus Society maintained that the current outbreak is not another COVID-19 outbreak.
So, first, let us understand all about the Andes Virus.
The Andes virus is a rare but highly dangerous pathogen of hantavirus, found primarily in Argentina and Chile. It is the only type of hantavirus known to man to spread among humans.
Unlike many hantaviruses seen in Europe, Asia, and North America, which are typically transmitted from infected rodents to humans, the Andes virus has repeatedly shown evidence of person-to-person spread.
As per experts, transmission usually occurs in situations involving prolonged or close contact. But how close is a question that has been recurring. The Hantavirus Society answers this.
“Over the past decades, multiple outbreak investigations, household clusters, nosocomial events, and genomic analyses have provided convincing evidence that ANDV can be transmitted between individuals under specific close-contact conditions. These may include household exposure, intimate contact, caregiving without suitable personal protective equipment, and prolonged exposure in poorly ventilated or crowded settings,” it said.
Pointing out decades of outbreak investigations, hospital clusters, and genetic studies, experts emphasized: “Human-to-human transmission of Andes virus should no longer be considered hypothetical”.
The scientists stressed that current evidence does not suggest the virus spreads easily through casual community interaction in the way diseases like measles, influenza, or COVID-19 do.
Also Read: Hantavirus Outbreak: How MV Hondius Passengers Will Be Screened And Evacuated
But the Andes virus is associated with hantavirus pulmonary syndrome (HPS) — a severe respiratory illness that can rapidly become fatal. Reported fatality rates range from 20% to 40%, depending on the outbreak setting, quality of medical care, and surveillance capacity.
Recent surveillance data highlight the seriousness of the disease:
The first major indication of person-to-person transmission emerged during the 1996 El Bolsón/Esquel outbreak. More recently, the 2018–2019 Epuyén outbreak infected 34 people after a single index case attended crowded social gatherings while symptomatic.
Strict public health interventions — including isolation, quarantine, and active contact tracing — reduced transmission.
Read More: Hantavirus: Israel Confirms 1st Case as UK, Spain Probe Suspected Infections; Should You Be Worried?
The Hantavirus Society noted that a confined environment aboard the MV Hondius means that passengers and crew may still be within the virus’s incubation period.
The scientists thus warned, "A negative PCR test shortly after exposure does not necessarily rule out future infection.” They recommend “ongoing monitoring, repeat testing where necessary, and antibody testing for close contacts”.
Experts are also examining whether transmission could occur during early or minimally symptomatic stages, rather than only after obvious illness begins.
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