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From controlling body temperature and flushing out toxins, adequate hydration plays a vital role in our general health and well-being, water is a life essential. However, while dehydration garners significant attention, overhydration, or drinking excessive amounts of water, is a condition that can have serious and sometimes fatal consequences.
Although it may sound bizarre since drinking water is said to be the solution for most health related problems it is important to recognize how much water is considered "too much" or the risks involved with being overhydrated can maintain a healthy balance.
Water intoxication, also termed hyperhydration, water poisoning or water toxemia, develops when an individual drinks much more water than the kidney can excrete. The main function of the kidneys in the human body is the processing and excretion of excess water. However, the human kidneys can process only up to 0.8 to 1.0 liters of water at a time. Drinking an amount that exceeds this may overwhelm the kidneys and put the electrolyte balance out of sync in the human body.
Electrolytes, especially sodium, are essential in maintaining fluid balance within and outside cells. Hyponatremia is the condition when sodium levels fall below 135 mmol/L, resulting from excessive water intake. This causes water to shift into cells, swelling them. In the brain, this can cause severe complications, including coma or even death.
The symptoms of water intoxication vary from mild to severe. Early symptoms are often similar to dehydration, which makes self-diagnosis challenging. Common symptoms include:
In more serious cases, water intoxication can cause seizures, loss of consciousness, or swelling in the brain. These complications can be fatal if left untreated.
A notable case occurred in 2007 when a woman participating in a water-drinking contest tragically died after consuming nearly two gallons of water in under two hours. More recently, actress Brooke Shields experienced a grand mal seizure attributed to excessive water consumption.
Water intoxication is rare, but certain scenarios can increase the risk:
These endurance athletes are prone to water intoxication, especially if they drink large amounts of water without replacing lost electrolytes. Hyponatremia usually happens during long races or marathons as individuals mistake fatigue and muscle cramps for dehydration and continue drinking water in excess.
Overhydration among military personnel is usually due to severe physical activity in extreme environmental conditions. The total number of hyponatremia cases documented from 2007 through 2022 for the active duty in the United States exceeds 1,600, with a note to this problem on exertion-related overhydration.
Compulsive water drinking, known as psychogenic polydipsia, is linked with some mental illnesses such as schizophrenia and psychosis. People with these conditions tend to drink too much water, causing a hazardous electrolyte imbalance.
Drugs such as MDMA (ecstasy) raise the body temperature and make people thirsty, and at times, some people tend to drink excess water at events like music festivals. MDMA also leads to urine retention, thus exacerbating the dangers of water intoxication.
The exact amount of water that causes intoxication varies from one person to another. However, drinking more than 1 liter of water per hour for several hours raises the risk. For healthy individuals, the risk of overhydration is low unless taking part in extreme physical activity or ignoring thirst cues.
Certain medical conditions, such as kidney or liver disorders, can impair the body's ability to process fluids, and even moderate water intake may be harmful. Similarly, certain medications, such as diuretics and antipsychotics, can affect the perception of thirst or fluid regulation.
The widely touted recommendation of eight 8-ounce glasses of water per day has little basis in fact. According to the National Academy of Medicine, a daily total fluid intake is about 15 cups (3.7 liters) for males and 11 cups (2.7 liters) for females, from beverage sources and from food. Usually, about 20 percent of daily hydration comes from foods such as fruits and vegetables.
A better rule of thumb is to listen to your body and drink water based on thirst. Use the color of your urine as an indicator:
Older adults, whose thirst mechanisms may decline with age, should be proactive about maintaining hydration, especially during illness or hot weather.
The symptoms of water intoxication—such as headaches, fatigue, and muscle weakness—are similar to those of dehydration. If you are unsure which condition you are experiencing, seek medical attention immediately rather than self-treating with more water.
To avoid the dangers of overhydration:
For signs of severe water intoxication-including confusion, drowsiness, seizures, and loss of consciousness-customer is advised to seek medical assistance immediately. In the meanwhile, a salty snack would help to temporarily correct low sodium levels.
Hydration is important to health, but overhydration can be a serious risk; the secret is in finding a balance. Drink enough water to satisfy your body, but not so much that it overwhelms your system. Remember, water is life, but moderation keeps it that way.
Hyponatremia (low sodium level in the blood). National Kidney Foundation. 2023.
Water Toxicity. NIH. 2023
Exercise-Associated Hyponatremia: 2017 Update. Front Med (Lausanne). 2017
Update: Exertional Hyponatremia Among Active Component Members of the U.S. Armed Forces, 2007–2022
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Heart stents have saved countless lives and remain one of the most effective treatments for blocked coronary arteries. By improving blood flow to the heart, they help relieve chest pain and lower the risk of serious events such as heart attacks. Today, stent placement is a routine, minimally invasive procedure performed on millions of patients each year. Yet as more people live longer with stents, an important question is gaining attention: how well do these devices hold up over time inside a constantly moving, living artery?
Stents are widely used to treat blocked or narrowed arteries, particularly in people with severe or advanced coronary artery disease. By restoring blood flow, they help ease chest pain, known as angina, which occurs when the heart muscle does not receive enough oxygen and nutrients because of reduced circulation.
Each year, millions of patients undergo stent procedures, making it one of the most commonly performed minimally invasive treatments worldwide. While stents have transformed heart care, it is still important to understand their limitations, especially as newer and more advanced technologies continue to emerge.
Before looking at how stents behave over time, it helps to understand the environment in which they are placed. We got in touch with Dr. Tamil Selvan Muthusamy, Primary Investigator in the MY-IVL Study of Elixir Medical’s Device and Consultant Cardiologist at Cardiac Vascular Sentral Kuala Lumpur (CVSKL), who told us, that coronary arteries, which supply blood to the heart, are living, flexible structures. They bend, twist, stretch, and move constantly with every heartbeat to manage changing blood flow and pressure.
These arteries travel along the surface of the heart, wrapping around its curves from base to tip, delivering oxygen-rich blood to every heart muscle cell. As the heart contracts and relaxes, the arteries shift side to side, stretch lengthwise, and twist repeatedly. Blood flow within them also changes throughout the heartbeat, moving more slowly during contraction and faster during relaxation. This constant motion creates friction and stress along the artery lining, known as the endothelium.
Under healthy conditions, this stress helps maintain vessel function. However, when blood flow is disrupted, small areas of damage can occur, allowing plaques to form, harden, and eventually block the artery.
A stent is a tiny metal mesh tube mounted on a deflated balloon catheter and guided through the arteries to the site of blockage. Once the balloon is inflated, the stent expands, pushing the plaque aside. The balloon is then removed, leaving the stent in place to keep the artery open, much like internal scaffolding.
Over the past two decades, research has shown that stents can behave like rigid cages inside arteries. Dr Selvan Muthusamy told us that depending on their length and position, they may restrict the artery’s natural ability to bend, twist, stretch, and pulse with each heartbeat. This stiffness can damage the delicate inner lining of the artery and increase stress on the vessel wall by limiting its natural movement.
When these mechanical changes alter normal blood flow patterns, they can trigger inflammation or excessive tissue growth inside the stent. This process, known as restenosis, is one of the main reasons stents fail over time. Long-term studies suggest that stents have an annual failure rate of around 2 to 3 percent. For patients, this may show up as the return of chest pain and, in some cases, can lead to a heart attack.
As explained by Dr Selvan Muthusamy, the challenge lies in matching rigid implants with arteries that are meant to move continuously. When this balance is disrupted, long-term complications become more likely.
Healthy habits play a major role in protecting stents and overall heart health. Patients are advised to stop smoking, follow a heart-friendly diet low in salt and unhealthy fats, and stay physically active, such as walking for at least 30 minutes a day.
Dr Selvan Muthusamy said, “Managing weight, blood sugar, blood pressure, and cholesterol is equally important. Taking prescribed medications consistently, participating in cardiac rehabilitation, and attending regular follow-up appointments all help reduce strain on the arteries and lower the risk of complications.”
In recent years, newer technologies have also been developed to address some of the mechanical drawbacks of traditional stents. One such innovation is the bioadaptor implant. Unlike conventional stents that remain permanently fixed, the bioadaptor is designed to change over time. After about six months of healing, it unlocks within the vessel wall and becomes a dynamic scaffold. This allows the artery to regain flexibility, stretch, and natural pulsation. Studies have shown improved blood flow, healthier artery lining, and more than 50 percent better long-term outcomes compared to standard stents.
The most common cause of stent failure is restenosis, where tissue growth gradually narrows the artery again. Patients should pay close attention to symptoms such as chest pain or pressure, shortness of breath, unusual fatigue, a rapid heartbeat, nausea, sweating, or swelling in the legs. These signs may become more noticeable during physical activity.
Seeking medical help promptly when these symptoms appear is critical. Early detection can prevent more serious complications, including heart attacks, and allow doctors to intervene before the problem becomes life-threatening.
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High blood pressure is a serious health issue, but it usually causes no obvious symptoms until significant harm has already occurred. This makes it difficult for many patients to stay consistent with their medication. When you do not feel any immediate change after missing a pill, it becomes easier to forget doses or stop altogether.
Many people assume it is “not a big deal” to skip a dose now and then, or even to quit the medicine completely. In reality, blood pressure medication is often meant to be taken long term, sometimes for life, though certain medicines may need to be stopped or switched during pregnancy. In some cases, people may be able to gradually reduce or fully stop their medication if major lifestyle changes lead to a clear and lasting drop in blood pressure.
Blood pressure medicines, also called antihypertensives, lower high blood pressure in different ways. They may relax blood vessels, lessen how hard the heart has to work, or reduce the amount of fluid in the body. These effects help lower the risk of serious problems such as heart attacks and strokes.
According to Medline Plus, these drugs work by blocking hormones that tighten blood vessels, helping the kidneys flush out excess salt and water, slowing the heart rate, or stopping calcium from tightening the arteries, which allows blood to move more freely.
If you miss a dose, it is usually best to take it as soon as you remember, unless it is close to the time for your next dose. Skipping one dose is generally less risky than taking too much. To avoid forgetting, it helps to take your medication at the same time every day and link it to a daily habit. For example, morning pills can be taken with breakfast, while evening pills can be kept near your toothbrush.
Along with choosing a regular time, your doctor may also suggest a specific time of day. One large study found that taking blood pressure medicine at bedtime significantly lowered the risk of heart attack.
According to Health Central, it is understandable to think about stopping your medication once your blood pressure readings improve and you feel well. However, you should never stop taking these medicines, especially all at once, without speaking to your doctor first.
Stopping blood pressure medication suddenly can lead to withdrawal effects that vary in severity, including:
When high blood pressure is no longer treated, your readings may return to previous levels or rise very quickly and dangerously, leading to what doctors call a hypertensive crisis. This is defined as a blood pressure reading above 180/120. It is a medical emergency and raises the risk of:
The harm caused by a hypertensive crisis is not always reversible and can sometimes be life-threatening.
If you and your doctor decide that trying life without blood pressure medication is possible and something you want to explore, the safest approach is tapering. This means slowly reducing the dose over time rather than stopping suddenly.
Before doing this, you will need to regularly monitor your blood pressure at home while still on medication and share those readings with your doctor. If your numbers stay consistently at the lower end of the normal range while on treatment, such as around 115/80 mmHg or lower, your doctor may consider gradually reducing your dependence on medication.
Disclaimer: This information is meant for general awareness only and should not be treated as medical advice. Blood pressure medications affect each person differently, and stopping or changing your dose without proper medical guidance can be dangerous. Always speak to a qualified doctor or healthcare provider before starting, adjusting, or discontinuing any medication.
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People who are prescribed a widely used medication are being advised to contact a doctor if they notice certain symptoms. As per Mirror, health officials say these “serious” side effects should not be delayed or ignored and may need medical review sooner rather than later. Diltiazem is a drug commonly given to manage high blood pressure. It is also sold under brand names such as Adizem, Angitil, Tildiem, Viazem, and Zemtard.
Doctors prescribe it to people with high blood pressure to lower the risk of coronary heart disease, heart attacks, and strokes. The medicine helps by reducing blood pressure and allowing the heart to pump blood more easily through the body. However, new warnings linked to the drug have now been highlighted.
Diltiazem belongs to a group of medicines called calcium channel blockers. It is used to treat high blood pressure, long-term stable angina, which causes chest pain, and certain types of irregular heartbeats. The drug works by relaxing blood vessels and easing the strain on the heart. According to Medline Plus, common side effects may include dizziness, headaches, swelling, and a slower heart rate. It is mainly prescribed for hypertension, angina, and heart rhythm conditions such as atrial fibrillation. In some cases, it is also used in cream form to help treat anal fissures.
The NHS website also states that diltiazem may be used to:
Like most medicines, diltiazem can cause side effects, although many people may not experience any. The NHS notes that there are several “common” side effects patients should be aware of.
These effects are seen in more than one in 100 people. The NHS explains: “They are usually mild and do not last long. There are ways to help manage them.”
They include:
The NHS adds: “Talk to a doctor or pharmacist if coping advice does not help, or if a side effect continues or becomes troublesome.”
In rare cases, diltiazem may lead to “serious side effects.” These are reported in fewer than one in 10,000 people.
According to the NHS, you should “stop taking diltiazem and contact a doctor or call 111 immediately” if:
You should also call 999 or go straight to A&E if you have chest pain that does not ease after a few minutes, or if chest pain is new or worse than usual when you already have angina. This may indicate a heart attack and requires urgent medical attention.
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