From controlling body temperature and flushing out toxins, adequate hydration plays a vital role in our general health and well-being, water is a life essential. However, while dehydration garners significant attention, overhydration, or drinking excessive amounts of water, is a condition that can have serious and sometimes fatal consequences.

Although it may sound bizarre since drinking water is said to be the solution for most health related problems it is important to recognize how much water is considered "too much" or the risks involved with being overhydrated can maintain a healthy balance.

What Is Water Intoxication?

Water intoxication, also termed hyperhydration, water poisoning or water toxemia, develops when an individual drinks much more water than the kidney can excrete. The main function of the kidneys in the human body is the processing and excretion of excess water. However, the human kidneys can process only up to 0.8 to 1.0 liters of water at a time. Drinking an amount that exceeds this may overwhelm the kidneys and put the electrolyte balance out of sync in the human body.

Electrolytes, especially sodium, are essential in maintaining fluid balance within and outside cells. Hyponatremia is the condition when sodium levels fall below 135 mmol/L, resulting from excessive water intake. This causes water to shift into cells, swelling them. In the brain, this can cause severe complications, including coma or even death.

Symptoms of Water Intoxication

The symptoms of water intoxication vary from mild to severe. Early symptoms are often similar to dehydration, which makes self-diagnosis challenging. Common symptoms include:

• Headaches
• Nausea and vomiting
• Muscle cramps or weakness
• Fatigue or drowsiness
• Confusion and disorientation

In more serious cases, water intoxication can cause seizures, loss of consciousness, or swelling in the brain. These complications can be fatal if left untreated.

A notable case occurred in 2007 when a woman participating in a water-drinking contest tragically died after consuming nearly two gallons of water in under two hours. More recently, actress Brooke Shields experienced a grand mal seizure attributed to excessive water consumption.

Causes of Water Intoxication

Water intoxication is rare, but certain scenarios can increase the risk:

1. Sporting Events and Endurance Training

These endurance athletes are prone to water intoxication, especially if they drink large amounts of water without replacing lost electrolytes. Hyponatremia usually happens during long races or marathons as individuals mistake fatigue and muscle cramps for dehydration and continue drinking water in excess.

2. Military Training

Overhydration among military personnel is usually due to severe physical activity in extreme environmental conditions. The total number of hyponatremia cases documented from 2007 through 2022 for the active duty in the United States exceeds 1,600, with a note to this problem on exertion-related overhydration.

3. Mental Health Conditions

Compulsive water drinking, known as psychogenic polydipsia, is linked with some mental illnesses such as schizophrenia and psychosis. People with these conditions tend to drink too much water, causing a hazardous electrolyte imbalance.

4. Drug Abuse

Drugs such as MDMA (ecstasy) raise the body temperature and make people thirsty, and at times, some people tend to drink excess water at events like music festivals. MDMA also leads to urine retention, thus exacerbating the dangers of water intoxication.

How Much Water Is Too Much?

The exact amount of water that causes intoxication varies from one person to another. However, drinking more than 1 liter of water per hour for several hours raises the risk. For healthy individuals, the risk of overhydration is low unless taking part in extreme physical activity or ignoring thirst cues.

Certain medical conditions, such as kidney or liver disorders, can impair the body's ability to process fluids, and even moderate water intake may be harmful. Similarly, certain medications, such as diuretics and antipsychotics, can affect the perception of thirst or fluid regulation.

How Much Water Is Enough?

The widely touted recommendation of eight 8-ounce glasses of water per day has little basis in fact. According to the National Academy of Medicine, a daily total fluid intake is about 15 cups (3.7 liters) for males and 11 cups (2.7 liters) for females, from beverage sources and from food. Usually, about 20 percent of daily hydration comes from foods such as fruits and vegetables.

A better rule of thumb is to listen to your body and drink water based on thirst. Use the color of your urine as an indicator:

• Light yellow urine indicates proper hydration.
• Dark yellow urine may indicate dehydration.

Older adults, whose thirst mechanisms may decline with age, should be proactive about maintaining hydration, especially during illness or hot weather.

Water Intoxication vs. Dehydration

The symptoms of water intoxication—such as headaches, fatigue, and muscle weakness—are similar to those of dehydration. If you are unsure which condition you are experiencing, seek medical attention immediately rather than self-treating with more water.

Preventing Water Intoxication

To avoid the dangers of overhydration:

• Drink water gradually throughout the day rather than consuming large amounts at once.
• Replace lost electrolytes post high-intensity exercise or heavy sweating.
• Consider using sports drinks or salty snacks to help replenish sodium.
• Keep track of fluid consumption during long-duration activities, and do not consume more water than the body is losing in terms of electrolytes.
• If on medications or have specific medical conditions, check with your doctor regarding the safety of drinking water.

For signs of severe water intoxication-including confusion, drowsiness, seizures, and loss of consciousness-customer is advised to seek medical assistance immediately. In the meanwhile, a salty snack would help to temporarily correct low sodium levels.

Hydration is important to health, but overhydration can be a serious risk; the secret is in finding a balance. Drink enough water to satisfy your body, but not so much that it overwhelms your system. Remember, water is life, but moderation keeps it that way.

Hyponatremia (low sodium level in the blood). National Kidney Foundation. 2023.

Water Toxicity. NIH. 2023

Exercise-Associated Hyponatremia: 2017 Update. Front Med (Lausanne). 2017

Update: Exertional Hyponatremia Among Active Component Members of the U.S. Armed Forces, 2007–2022

Sharing a health update of the beloved actor Bruce Willis, his wife Emma Hemmings opened up about how the condition is affecting the actor. In an interview with NewsNation, she spoke on the misconception that the Die-Hard superstar had Alzheimer’s.

“FTD isn’t Alzheimer’s,” she stressed. She clarified that while Frontotemporal Dementia (FTD) affects his ability to communicate and behave, “Bruce doesn’t have Alzheimer’s. So, he does know who we are.”

She noted that while he struggles to verbalize his love, words are not necessary for their family. "We don’t need words," she said. "We have a very deep connection, and we have learned to sort of meet him where he’s at." FTD symptoms can include difficulty with speech, changes in personality, and slow movements, and there is currently no cure.

The Alzheimer’s Research Association explains that dementia is an "umbrella term" used to describe problems with memory, thinking, and reasoning. It's not a single disease. Instead, diseases like Frontotemporal Dementia (FTD) and Alzheimer's are two different causes that lead to similar, but different symptoms.

It is very important for doctors to know the differences between FTD and Alzheimer's. Getting the correct diagnosis early helps patients get the right treatment sooner. This can greatly improve their health and overall quality of life.

How Is FTD Different from Alzheimer’s Disease?

The biggest difference between these two conditions is which part of the brain they damage first. This difference explains why the early symptoms are so distinct.

What Part of the Brain Does FTD affect?

Frontotemporal Dementia (FTD), as its name suggests, mainly affects the front (frontal) and sides (temporal) of the brain. These areas are like the control center for your personality, behavior, and language skills. For example, the frontal lobe handles judgment and controlling your emotions, and the temporal lobe helps you process what you hear and form memories.

What Part of the Brain Does Alzheimer’s Affect?

In contrast, Alzheimer's disease usually starts by damaging areas crucial for memory, such as the hippocampus. These are the parts of the brain that help you learn new things and retrieve old memories. As Alzheimer's gets worse, the damage spreads to more areas of the brain, affecting memory, behavior, language, and even how you see things.

What Ages Do FTD and Alzheimer’s Typically Start?

Another key difference is when people usually start showing symptoms.

FTD often begins when people are younger, typically between 40 and 60 years old. This is why it's sometimes called an earlier-onset dementia.

Alzheimer's is much more common in older adults, usually affecting people who are 65 and over. Getting older is the biggest risk factor for Alzheimer's, but remember, it is not a normal part of getting older or healthy aging.

How Are The Symptoms of FTD different from Alzheimer’s?

While both diseases cause dementia, the first symptoms are usually very distinct, which helps doctors tell them apart.

In early Alzheimer's, the main symptom is memory loss.

• Often forgetting recent conversations or events.
• Having trouble with spatial orientation, which means they might get lost in places they know well.
• Struggle to find the right word, their ability to speak clearly and understand others usually stays better for longer than in FTD.
• Delusions or hallucinations also happen more often as Alzheimer's gets worse.

In early FTD, the initial signs are usually behavioral changes or language problems.

• Acting impulsively
• Lose their filter in conversation
• Become very withdrawn.

This is common in the most frequent type of FTD, called behavioral variant FTD (bvFTD). In another type of FTD called Primary Progressive Aphasia (PPA), the first problem is a difficulty with,

• Speaking
• Understanding language
• Writing.
• While people with advanced FTD will eventually have memory loss, it's not the primary symptom at the beginning.

How Has FTD Affected Bruce Willis?

In the interview Emma Hemmings admitted Bruce is unaware of his frontotemporal dementia (FTD) diagnosis.

She explained that it is a part of the disease itself for the person not to realize their health is declining. When asked about a fear that Willis might have voiced his distress about his condition, she confirmed:

"The person doesn’t realize that they are experiencing a decline in their health. So it’s not denial; this is just a part of the disease. So, it’s a blessing and a curse. But I am grateful that Bruce never tapped into the idea that he had FTD.”

What's making headlines up recently is a new study, which yet has not been peer reviewed about how sleep medicine could have adverse affects on your cardiovascular health. Melatonin, which is a hormone produced naturally by the body to regulate the sleep-wake cycle, is also sold as dietary supplement, typically made synthetically, has been linked to causing heart failure.

The research is from an unpublished study that is set to be presented at the American Heart Association's scientific conference in New Orleans next week. The research notes that the sleep supplement could be linked to 90% increase in heart failure. This has drawn mixed reactions from sleep medicine experts and cardiologists. The experts have urged the public not to panic, and have called for more research into using melatonin for longer duration. Experts who have reviewed the study have noted for the limitations, which has made it challenging to determine whether and how long-term use of the sleep supplement could lead to heart failure. This happens when your heart is not pumping as well as it should.

As per Muhammad Rishi, an associate professor of clinical medicine and spokesperson for the American Academy of Sleep Medicine, "The findings are certainly provocative and warrant attention, especially given the widespread perception of melatonin as a benign, ‘natural’ sleep aid. However, the study is observational and based on electronic health record data, which limits its ability to establish causality."

What Is The Relation Between Melatonin And Heart?

Melatonin is secreted by brain's pineal gland in the evening, and it signals the body for sleep time. However, there are doctors who do not recommend using the supplement to treat chronic insomnia, reports the Washington Post. The reason being that the evidence for its efficacy is limited and inconsistent. The experts note that there is lack of data on its long-term usage.

In the US, melatonin does not require any prescription, however, experts have pointed out that it can only help people to treat sleep-timing problems due to jet lag or shift work, on low doses. Without being prescribed, these medicines could be procured over-the-counter, and could be used to treat chronic sleep disorders without proper guidance.

The new study that analyzed the international database of health records from five years of over 130,000 adults diagnosed with insomnia was able to recognize 65,000 participants who had been prescribed the supplement at least once for one year. The study noted that over the course of five years, around 3,000 people who took had melatonin experienced heart failure.

People who had already been diagnosed with heart failure, or were prescribed other sleep medicines, were excluded from the study.

The patients who took melatonin, were then compared with the ones who did not have melatonin, but had insomnia. The researchers found that this comparison allowed them to account for a variety of factors that could link a person's risk for heart failure, including other health conditions.

Ekenedilichukwu Nnadi, the lead author of the new report and chief resident in internal medicine at SUNY Downstate/Kings County Primary Care in Brooklyn, said, "What stood out most was that we found any association at all."

Nnadi said, "Melatonin is generally viewed as a very safe supplement, as something people, and even physicians, don’t usually worry much about, so we honestly didn’t expect to see a clear signal linking long-term use with higher rates of heart failure, hospitalizations and death.” However, the lead author did emphasize that the findings only showed association and not causation.

He said that the study does not prove that melatonin directly causes heart failure. “It simply shows that people with chronic insomnia who took melatonin long term were more likely to experience these outcomes. It’s an unexpected and important signal that needs to be studied further, ideally in randomized trials.”

The NHS has issued a warning for anyone using a common painkiller, highlighting possible harmful interactions with other medications. Across the UK, many people turn to over-the-counter medicines for daily aches, colds, and minor illnesses. Among these, paracetamol is one of the most widely used, often taken for headaches, back pain, and cold symptoms. But, like any medication, it carries certain risks.

Who Should Be Careful?

The NHS has provided guidance on using paracetamol safely, including which drug combinations should be avoided. “Paracetamol is not suitable for some people,” the health body explains. This includes individuals who take warfarin, a drug that prevents blood clots. If you are on warfarin, you should check with your GP before taking paracetamol, the NHS advises. “Paracetamol can raise the risk of bleeding in those who regularly take warfarin.”

Safe Dosing Guidelines

Small doses of paracetamol alongside warfarin are generally considered safe. The NHS adds: “It’s safe to take paracetamol if you’re on warfarin. Stick to the lowest dose that relieves your pain. Exceeding four 500mg tablets in 24 hours for more than a few days can slow your blood clotting, putting you at risk of bleeding.”

Avoid Double Dosing

Combining paracetamol with other medicines containing the same ingredient—like co-codamol or some cold and flu remedies—can be risky due to the danger of overdose. Other common painkillers, such as ibuprofen, aspirin, or codeine, do not contain paracetamol and can safely be taken at the same time.

Check with Your Doctor

The NHS advises consulting a doctor before taking paracetamol if you’re on medications for epilepsy or tuberculosis (TB), as these combinations can also pose risks.

Herbal Remedies and Supplements

Generally, paracetamol is not affected by herbal supplements, though the NHS notes: “There isn’t enough information to say whether herbal remedies, complementary medicines, or supplements are safe with paracetamol. They are not tested the same way as prescription or pharmacy medications and may interact differently.” Patients should inform their doctor or pharmacist about any other medicines or supplements they are taking.

Side Effects of Paracetamol

When taken at the recommended dose, paracetamol “very rarely” causes side effects. For a full list, refer to the information leaflet inside the packaging.

Serious Allergic Reactions

In rare cases, a serious allergic reaction (anaphylaxis) can occur. The NHS advises calling 999 immediately if you notice:

• Swelling of lips, mouth, throat, or tongue
• Rapid or labored breathing, wheezing, or a choking sensation
• A tight throat or difficulty swallowing
• Skin, lips, or tongue turning blue, grey, or pale (on darker skin, check palms or soles)
• Sudden confusion, extreme drowsiness, or dizziness
• Fainting and unresponsiveness
• A child appearing limp, floppy, or unresponsive, with difficulty lifting or focusing their head