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From controlling body temperature and flushing out toxins, adequate hydration plays a vital role in our general health and well-being, water is a life essential. However, while dehydration garners significant attention, overhydration, or drinking excessive amounts of water, is a condition that can have serious and sometimes fatal consequences.
Although it may sound bizarre since drinking water is said to be the solution for most health related problems it is important to recognize how much water is considered "too much" or the risks involved with being overhydrated can maintain a healthy balance.
Water intoxication, also termed hyperhydration, water poisoning or water toxemia, develops when an individual drinks much more water than the kidney can excrete. The main function of the kidneys in the human body is the processing and excretion of excess water. However, the human kidneys can process only up to 0.8 to 1.0 liters of water at a time. Drinking an amount that exceeds this may overwhelm the kidneys and put the electrolyte balance out of sync in the human body.
Electrolytes, especially sodium, are essential in maintaining fluid balance within and outside cells. Hyponatremia is the condition when sodium levels fall below 135 mmol/L, resulting from excessive water intake. This causes water to shift into cells, swelling them. In the brain, this can cause severe complications, including coma or even death.
The symptoms of water intoxication vary from mild to severe. Early symptoms are often similar to dehydration, which makes self-diagnosis challenging. Common symptoms include:
In more serious cases, water intoxication can cause seizures, loss of consciousness, or swelling in the brain. These complications can be fatal if left untreated.
A notable case occurred in 2007 when a woman participating in a water-drinking contest tragically died after consuming nearly two gallons of water in under two hours. More recently, actress Brooke Shields experienced a grand mal seizure attributed to excessive water consumption.
Water intoxication is rare, but certain scenarios can increase the risk:
These endurance athletes are prone to water intoxication, especially if they drink large amounts of water without replacing lost electrolytes. Hyponatremia usually happens during long races or marathons as individuals mistake fatigue and muscle cramps for dehydration and continue drinking water in excess.
Overhydration among military personnel is usually due to severe physical activity in extreme environmental conditions. The total number of hyponatremia cases documented from 2007 through 2022 for the active duty in the United States exceeds 1,600, with a note to this problem on exertion-related overhydration.
Compulsive water drinking, known as psychogenic polydipsia, is linked with some mental illnesses such as schizophrenia and psychosis. People with these conditions tend to drink too much water, causing a hazardous electrolyte imbalance.
Drugs such as MDMA (ecstasy) raise the body temperature and make people thirsty, and at times, some people tend to drink excess water at events like music festivals. MDMA also leads to urine retention, thus exacerbating the dangers of water intoxication.
The exact amount of water that causes intoxication varies from one person to another. However, drinking more than 1 liter of water per hour for several hours raises the risk. For healthy individuals, the risk of overhydration is low unless taking part in extreme physical activity or ignoring thirst cues.
Certain medical conditions, such as kidney or liver disorders, can impair the body's ability to process fluids, and even moderate water intake may be harmful. Similarly, certain medications, such as diuretics and antipsychotics, can affect the perception of thirst or fluid regulation.
The widely touted recommendation of eight 8-ounce glasses of water per day has little basis in fact. According to the National Academy of Medicine, a daily total fluid intake is about 15 cups (3.7 liters) for males and 11 cups (2.7 liters) for females, from beverage sources and from food. Usually, about 20 percent of daily hydration comes from foods such as fruits and vegetables.
A better rule of thumb is to listen to your body and drink water based on thirst. Use the color of your urine as an indicator:
Older adults, whose thirst mechanisms may decline with age, should be proactive about maintaining hydration, especially during illness or hot weather.
The symptoms of water intoxication—such as headaches, fatigue, and muscle weakness—are similar to those of dehydration. If you are unsure which condition you are experiencing, seek medical attention immediately rather than self-treating with more water.
To avoid the dangers of overhydration:
For signs of severe water intoxication-including confusion, drowsiness, seizures, and loss of consciousness-customer is advised to seek medical assistance immediately. In the meanwhile, a salty snack would help to temporarily correct low sodium levels.
Hydration is important to health, but overhydration can be a serious risk; the secret is in finding a balance. Drink enough water to satisfy your body, but not so much that it overwhelms your system. Remember, water is life, but moderation keeps it that way.
Hyponatremia (low sodium level in the blood). National Kidney Foundation. 2023.
Water Toxicity. NIH. 2023
Exercise-Associated Hyponatremia: 2017 Update. Front Med (Lausanne). 2017
Update: Exertional Hyponatremia Among Active Component Members of the U.S. Armed Forces, 2007–2022
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Ahead of Diwali festivities, Delhi is once again battling its annual air pollution crisis. The city's air quality index (AQI) - which measures PM2.5, fine particulate matter, has crossed 500 in some regions, entering the "hazardous" category, raising health concerns for millions in the capital.
The effects of air pollution are not just limited to physical health. Apart from your lungs and heart, long-term exposure to toxic air can render you feeling anxious, stressed, demotivated and mentally fatigued.
The reason behind this is not one-fold. The worsening of mental health due to air pollution is a culmination of many factors.
From particulate matter triggering inflammation and negatively affecting the body’s stress response to restrictions on outdoor activities, disturbance in sleep and lack of physical activity, air pollution contributes to mental health burden in many ways.
Dr Varsha Viswanathan, psychiatrist at Athulya Senior Care and Athulya Geriatric Care Hospital, Chennai, told HealthandMe that particulate matter in polluted air can enter the bloodstream and trigger inflammatory responses.
She explained, “This may lead to oxidative stress and affect brain functions involved in mood regulation, attention, memory and emotional processing. Over time, these changes may contribute to increased irritability, mood disturbances and difficulty managing emotional responses.”
Also read: Climate Crisis Is A Health Crisis: Just 6 Actions Could Save 1.6 Million Lives, Says WHO
PM2.5, consists of tiny airborne particles that can penetrate into the lungs. Some can even enter the bloodstream and cause inflammation and oxidative stress. These effects may also affect the brain and its functions.
Cortisol is a hormone related to the body’s response to stress. Changes in stress regulation due to pollution may make it harder for some individuals to manage everyday challenges. Dr Viswanathan explains that air pollution may also affect the body’s stress-response system.
“Repeated exposure to environmental pollutants can affect the regulation of stress hormones such as cortisol. This may increase physiological stress and contribute to symptoms such as restlessness, heightened alertness, difficulty relaxing and persistent feelings of tension,” she says.
Also read: Air Pollution In Delhi: Experts Warn Of Red Eyes, Itching, Watering In Children
Apart from stress, living in highly polluted cities can also cause one to feel constantly uncomfortable, uncertain and anxious. Kakul Faruqi, Senior Consultant Psychologist at LH Hiranandani Hospital, Mumbai, told HealthandMe that pollution can become a source of fear and withdrawal.
She said that someone who is prone to anxiety, breathing difficulty may be interpreted as a sign of immediate danger, which could trigger further fear and distress.
“Psychologically speaking, pollution can be a source of discomfort, fear and withdrawal. A coughing fit, trouble breathing and insomnia can exhaust an individual, making it more difficult for him or her to cope with daily stresses. An individual who is susceptible to panic attacks can experience fear and negative interpretations of physical symptoms due to trouble breathing,” Faruqi explains.
She also said that repeated exposure can also make the threat feel inescapable. Faruqi says that when individuals perceive pollution as a problem beyond their control, the resulting uncertainty can become extremely overwhelming.
Faruqi explains that pollution can make it harder to engage in behaviours that support psychological health.
When pollution levels are high, people normally avoid spending time outside socialising, exercising, walking, and spending time in green spaces. These activities often provide opportunities for physical movement, social connection and relaxation. Missing out on these activities can affect one emotional and mental well-being.
“The reduction in outlets for relaxation, in addition to experiencing feelings of loneliness and frustration, can lead to depression,” she says.
Dr Viswanathan also highlights how poor air quality can disrupt sleep, physical activity and normal social routines, which could further worsen mental well-being.
“Inadequate sleep and reduced physical activity can, in turn, affect emotional regulation, concentration and the ability to cope with everyday stress,” she says.
When AQI is high, it is important to reduce exposure but at the same time, maintaining routines that help psychological well-being is also important. Faruqi recommends checking air quality in one’s locality, adjusting exercise habits accordingly and making an effort to preserve sleep and social interaction.
Some practical measures include:
Faruqi advises that “if one experiences persisting anxiety, depression, or impairment in functioning, a visit to a mental health professional would be advisable.”
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Novo Nordisk’s GLP-1 weight loss pill, Wegovy, has been approved in Australia for sale. An alternative to weekly weight loss injections, the Therapeutic Goods Administration (TGA) has cleared Wegovy, which contains semaglutide, the same active ingredient found in GLP-1 weight loss injections: Wegovy and Ozempic.
The pill received TGA approval on November 3, 2026, and is expecting to reach the shelves by Christmas.
It is prescribed to eligible adults to help manage chronic obesity along with lifestyle changes. It is also approved to reduce the risk of major cardiovascular events in eligible patients.
Until now, Australians seeking GLP-1 medication for weight management have primarily had access to injectable formulations. The tablet offers a different approach.
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The new tablet contains semaglutide, a GLP-1 receptor agonist that mimics the action of the naturally occurring glucagon-like peptide-1 hormone.
GLP-1 medications act on appetite regulation. They help users feel full, reduce cravings and slow stomach emptying, which can lead to lower calorie intake and weight loss.
Unlike injectable Wegovy, which is administered once a week, this tablet should be taken every day.
The TGA has approved four tablet strengths for sale: 1.5 mg, 4 mg, 9 mg and 25 mg. Treatment starts at a lower dose, which is gradually increased over approximately 16 weeks under medical supervision. The tablet also has specific use requirements. Patients must:
The fasting instructions are important because semaglutide is absorbed less efficiently when taken orally. So following that instruction is crucial as a 25 mg tablet has to achieve an effect comparable to the 2.4 mg weekly injectable Wegovy dose.
The TGA approval covers adults who meet specific weight-related criteria. These include:
These conditions may include high blood pressure, abnormal cholesterol levels, type 2 diabetes, fatty liver disease or other weight-related complications.
The medication is also approved to reduce the risk of major adverse cardiovascular events in eligible adults with cardiovascular disease and those who are overweight or obese but don’t have diabetes.
However, approval does not mean everyone meeting these criteria should automatically take the medication. A doctor must assess your health, medical history, and risks before prescribing it.
Dr Brendan Hanrahan, an obesity medicine specialist at Brisbane's Wesley Hospital, welcomed wider access to the medication, saying GLP-1 drugs have "lived up to and exceeded the hype". However, he questioned whether BMI alone is enough to determine eligibility.
He suggested waist circumference could offer some information about health risks, saying that some people may experience complications related to weight even when their BMI falls within the ‘normal’ healthy range.
The oral pill does not eliminate the side effects associated with semaglutide. Common adverse effects include:
Gastrointestinal symptoms can sometimes lead to dehydration, which may increase the risk of kidney problems.
The TGA also warns about more serious complications, including acute pancreatitis and diabetic retinopathy. People with diabetes, particularly those with pre-existing eye disease, may need clinical monitoring.
Semaglutide is not recommended during pregnancy, and people planning to become pregnant should discuss treatment and timing with their doctor.
The TGA has also warned of depression and suicidal thoughts or behaviours linked with GLP-1 medications.
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A breast cancer diagnosis can change more than a woman’s immediate health priorities. Suddenly, appointments, treatment decisions and medical advice become part of everyday life, alongside work deadlines, family responsibilities, relationships and personal plans. Even as women focus on getting better, questions about how treatment might affect their routines, independence and future can be difficult to navigate.
For women diagnosed with early breast cancer, treatment offers an opportunity to address the disease and reduce the risk of it returning. But the experience is about more than medical outcomes alone. How women feel during treatment, the support available to them and their ability to continue doing the things that matter to them are also important considerations.
Treating early breast cancer involves looking beyond the immediate diagnosis to understand what matters to each patient. While our priority is to recommend treatment that offers the best possible clinical benefit, it is equally important to discuss how treatment may affect everyday life, from managing side effects to maintaining relationships and planning for the future. By encouraging open conversations about advanced therapies and addressing patients’ concerns early, we can help women make informed decisions while supporting their quality of life throughout the treatment journey.
Here are four ways women can approach treatment while keeping their personal well-being in focus.
Breast cancer treatment can affect everyday life in different ways, from recovery after surgery to managing side effects or making time for regular appointments. For women balancing work, family responsibilities and personal commitments, understanding what treatment involves can help them plan ahead and arrange the support they need.
Advances in breast cancer care have expanded treatment options for eligible patients, with some targeted therapies offering a more tailored approach that may help reduce certain treatment-related side effects. Understanding the potential benefits and impact of each option on quality of life can help women make informed decisions with their oncologist. Discussing how treatment may affect daily routines, energy levels and recovery can also help women plan for the journey ahead while continuing to prioritise what matters to them.
Breast cancer treatment affects every woman differently. Depending on the therapy, side effects may include fatigue, nausea, joint pain, sleep disturbances or changes in hair and weight, potentially making everyday activities more challenging.
Women should discuss potential side effects with their healthcare team and seek advice early on, as appropriate interventions can help manage symptoms. Gentle physical activity, a balanced diet and adequate rest may also support overall well-being, depending on individual needs and medical advice. The goal is to find a manageable routine that supports recovery and quality of life without putting every other aspect of life on hold.
The emotional impact of breast cancer can be as significant as the physical effects. Uncertainty about the future, changes in body image and concerns about loved ones can affect emotional well-being. Talking to trusted friends, joining a support group or seeking professional guidance can help women navigate these challenges, while open conversations with family can make it easier to ask for support.
Personal concerns, including fertility, intimacy and sexual health, also deserve attention. Women should discuss these with their healthcare team before treatment begins, particularly when fertility preservation may be an option. Addressing these concerns early can help women understand their choices and ensure their emotional well-being and personal priorities remain part of the treatment journey.
Looking beyond initial treatment can help women prepare for the next stages of care. Depending on the cancer’s characteristics, doctors may recommend additional treatment to reduce recurrence risk, with some women continuing medication for several years. Understanding the purpose, expected benefits and duration of treatment can help women plan ahead.
Regular follow-up appointments remain important for monitoring recovery and addressing new symptoms or ongoing side effects. If treatment becomes difficult to manage, women should speak to their healthcare team, who may suggest ways to manage symptoms or explore suitable alternatives. Staying informed about the care plan can help women look ahead with greater confidence while prioritising their long-term health and quality of life.
An early breast cancer diagnosis can bring uncertainty, but it does not erase the other parts of a woman’s life. Work, relationships, family, personal ambitions and everyday pleasures remain important, even while treatment becomes a priority.
Making space for these aspects of life starts with asking questions, communicating concerns and seeking support before challenges become overwhelming. Clinical outcomes and recurrence risk remain important considerations, but so does the experience of living through treatment.
The goal is not to manage every aspect of the journey perfectly. It is to ensure that women have the information, care and support they need to navigate treatment in a way that considers both their health and their quality of life.
By Dr. Sachin Sekhar Biswal, Consultant Medical Oncologist, Manipal Hospital, Bhubaneswar
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