From controlling body temperature and flushing out toxins, adequate hydration plays a vital role in our general health and well-being, water is a life essential. However, while dehydration garners significant attention, overhydration, or drinking excessive amounts of water, is a condition that can have serious and sometimes fatal consequences.

Although it may sound bizarre since drinking water is said to be the solution for most health related problems it is important to recognize how much water is considered "too much" or the risks involved with being overhydrated can maintain a healthy balance.

What Is Water Intoxication?

Water intoxication, also termed hyperhydration, water poisoning or water toxemia, develops when an individual drinks much more water than the kidney can excrete. The main function of the kidneys in the human body is the processing and excretion of excess water. However, the human kidneys can process only up to 0.8 to 1.0 liters of water at a time. Drinking an amount that exceeds this may overwhelm the kidneys and put the electrolyte balance out of sync in the human body.

Electrolytes, especially sodium, are essential in maintaining fluid balance within and outside cells. Hyponatremia is the condition when sodium levels fall below 135 mmol/L, resulting from excessive water intake. This causes water to shift into cells, swelling them. In the brain, this can cause severe complications, including coma or even death.

Symptoms of Water Intoxication

The symptoms of water intoxication vary from mild to severe. Early symptoms are often similar to dehydration, which makes self-diagnosis challenging. Common symptoms include:

• Headaches
• Nausea and vomiting
• Muscle cramps or weakness
• Fatigue or drowsiness
• Confusion and disorientation

In more serious cases, water intoxication can cause seizures, loss of consciousness, or swelling in the brain. These complications can be fatal if left untreated.

A notable case occurred in 2007 when a woman participating in a water-drinking contest tragically died after consuming nearly two gallons of water in under two hours. More recently, actress Brooke Shields experienced a grand mal seizure attributed to excessive water consumption.

Causes of Water Intoxication

Water intoxication is rare, but certain scenarios can increase the risk:

1. Sporting Events and Endurance Training

These endurance athletes are prone to water intoxication, especially if they drink large amounts of water without replacing lost electrolytes. Hyponatremia usually happens during long races or marathons as individuals mistake fatigue and muscle cramps for dehydration and continue drinking water in excess.

2. Military Training

Overhydration among military personnel is usually due to severe physical activity in extreme environmental conditions. The total number of hyponatremia cases documented from 2007 through 2022 for the active duty in the United States exceeds 1,600, with a note to this problem on exertion-related overhydration.

3. Mental Health Conditions

Compulsive water drinking, known as psychogenic polydipsia, is linked with some mental illnesses such as schizophrenia and psychosis. People with these conditions tend to drink too much water, causing a hazardous electrolyte imbalance.

4. Drug Abuse

Drugs such as MDMA (ecstasy) raise the body temperature and make people thirsty, and at times, some people tend to drink excess water at events like music festivals. MDMA also leads to urine retention, thus exacerbating the dangers of water intoxication.

How Much Water Is Too Much?

The exact amount of water that causes intoxication varies from one person to another. However, drinking more than 1 liter of water per hour for several hours raises the risk. For healthy individuals, the risk of overhydration is low unless taking part in extreme physical activity or ignoring thirst cues.

Certain medical conditions, such as kidney or liver disorders, can impair the body's ability to process fluids, and even moderate water intake may be harmful. Similarly, certain medications, such as diuretics and antipsychotics, can affect the perception of thirst or fluid regulation.

How Much Water Is Enough?

The widely touted recommendation of eight 8-ounce glasses of water per day has little basis in fact. According to the National Academy of Medicine, a daily total fluid intake is about 15 cups (3.7 liters) for males and 11 cups (2.7 liters) for females, from beverage sources and from food. Usually, about 20 percent of daily hydration comes from foods such as fruits and vegetables.

A better rule of thumb is to listen to your body and drink water based on thirst. Use the color of your urine as an indicator:

• Light yellow urine indicates proper hydration.
• Dark yellow urine may indicate dehydration.

Older adults, whose thirst mechanisms may decline with age, should be proactive about maintaining hydration, especially during illness or hot weather.

Water Intoxication vs. Dehydration

The symptoms of water intoxication—such as headaches, fatigue, and muscle weakness—are similar to those of dehydration. If you are unsure which condition you are experiencing, seek medical attention immediately rather than self-treating with more water.

Preventing Water Intoxication

To avoid the dangers of overhydration:

• Drink water gradually throughout the day rather than consuming large amounts at once.
• Replace lost electrolytes post high-intensity exercise or heavy sweating.
• Consider using sports drinks or salty snacks to help replenish sodium.
• Keep track of fluid consumption during long-duration activities, and do not consume more water than the body is losing in terms of electrolytes.
• If on medications or have specific medical conditions, check with your doctor regarding the safety of drinking water.

For signs of severe water intoxication-including confusion, drowsiness, seizures, and loss of consciousness-customer is advised to seek medical assistance immediately. In the meanwhile, a salty snack would help to temporarily correct low sodium levels.

Hydration is important to health, but overhydration can be a serious risk; the secret is in finding a balance. Drink enough water to satisfy your body, but not so much that it overwhelms your system. Remember, water is life, but moderation keeps it that way.

Hyponatremia (low sodium level in the blood). National Kidney Foundation. 2023.

Water Toxicity. NIH. 2023

Exercise-Associated Hyponatremia: 2017 Update. Front Med (Lausanne). 2017

Update: Exertional Hyponatremia Among Active Component Members of the U.S. Armed Forces, 2007–2022

Nearly one in seven couples struggles with infertility, meaning they haven’t been able to conceive despite having regular, unprotected sex for a year or more. In roughly half of these couples, male infertility is at least partially responsible. Causes can range from low sperm production and abnormal sperm function to blockages that prevent sperm delivery.

Illnesses, injuries, chronic conditions, lifestyle factors, and other influences may contribute. Not being able to conceive can be stressful and emotionally challenging, but a variety of treatments exist for male infertility. But are there natural ways to improve male fertility? We spoke with Dr. Ruchi Jain, Fertility Specialist at Nova IVF Fertility, Kolkata, to get her insights.

What Is Male Infertility?

Male infertility refers to a man’s inability to cause pregnancy in a fertile female partner, often due to problems with sperm production, function, or delivery. After a year of trying (or six months if the woman is over 35) without success, doctors usually examine both partners. About 50% of infertility cases involve male factors, with the most common issues being low sperm count (oligospermia), poor motility, abnormal morphology, or the complete absence of sperm in the ejaculate (azoospermia), Dr Jain explained. Some causes are temporary, some treatable, and some may be permanent.

Can Male Infertility Be Treated Naturally?

Many men experience noticeable improvement by focusing on lifestyle changes and addressing reversible medical conditions. Research shows that a nutritious diet (like a Mediterranean-style or “prudent” diet), regular moderate exercise, quitting smoking, reducing alcohol, losing excess weight, and avoiding heat or tight underwear can improve sperm quality.

Dr. Jain noted, “These adjustments don’t guarantee conception, but they often enhance sperm count, motility, and DNA quality enough to support natural conception or assisted reproductive techniques.”

Medical Fixes That Can Restore Fertility

Certain medical conditions that cause infertility can often be reversed. For example, varicoceles, which are enlarged veins in the scrotum—are a common cause; repairing a significant varicocele frequently improves semen parameters and can lead to pregnancy.

Hormonal issues, such as low testosterone or pituitary disorders, may also be treated with medication. Dr. Jain said, “Temporary causes like infections, medications, or recent fevers can lower sperm counts, which often normalize within a few months once the underlying issue is resolved. Professional guidelines highlight that many male-factor infertility cases can respond well to medical or surgical treatment.”

Is Male Infertility Permanent?

Dr Jain told us that some conditions are extremely difficult or impossible to “cure.” Genetic disorders (like Klinefelter syndrome), congenital absence of the vas deferens, severe testicular failure, or damage from chemotherapy or radiation usually prevent normal sperm production.

In these cases, treatment focuses on alternatives: retrieving sperm directly from the testicles, using IVF with ICSI (intracytoplasmic sperm injection), donor sperm, or adoption. Recent studies show that sperm retrieval after certain procedures can improve success rates, but outcomes depend heavily on the underlying condition of the testicles.

What About Supplements, Herbs, and “Natural” Cures?

Interest in antioxidants (vitamins C and E, zinc, L-carnitine), herbal remedies (maca, ginseng), and bioactive compounds (resveratrol, curcumin) is rising. Some research reports modest improvements in sperm quality, while other studies show mixed or minimal effects.

However, experts caution that supplements aren’t a miracle solution, quality varies, and evidence remains limited. Always consult a specialist before trying supplements, as some may interact with medications or cause harm at high doses.

Big-Picture Threats and Prevention

Even with personal lifestyle changes, environmental factors play a major role. Global air pollution, pesticides, plastics, and other endocrine-disrupting chemicals are linked to long-term declines in sperm counts. While an individual cannot control these entirely, reducing exposure (avoiding unnecessary plastics, limiting contact with heat or chemicals, choosing organic or well-washed produce) and advocating for public health measures are practical steps. Recent global reviews have highlighted these environmental threats to male fertility.

How To Reverse Male Infertility?

Male infertility is not always permanent. Many causes, such as obstructions, varicoceles, hormonal imbalances, or infections—can be treated or reversed. Lifestyle changes and certain medical or surgical interventions can improve outcomes for many men.

Conversely, genetic factors, severe testicular damage, and gonadotoxic injuries are usually irreversible, requiring assisted reproductive techniques or other family-building options. A structured diagnostic assessment and an individualized treatment plan—including genetic counseling when needed are essential.

What happens when antibiotics stop working? We are so used to consuming antibiotics for everything that slowly our bodies are rejecting this. The sole reason is that bacteria have become smart. And experts believe that if this continues, it could slip the world back into an era where even a minor infection would be dangerous.

Antibiotics are used to treat almost all infections. However, with the sudden outbreaks, the misuse and overuse of it is slowly leading to antibiotic resistance or antimicrobial resistance (AMR). As per the World Health Organization (WHO), AMR occurs when bacteria, viruses, fungi, and parasites no longer respond to antimicrobial medicines.

What could Happen When Antibiotics Stop Working?

As experts warn, infections we currently consider minor could soon turn life-threatening. A routine urine infection, a scraped knee, or a mild chest infection, problems that usually resolve within days, may refuse to heal in the future. Bacteria evolve rapidly, and when exposed to unnecessary or incomplete antibiotic courses, they adapt and learn to survive. That’s when even our strongest medicines begin to fail.

Antibiotics do far more than treat common illnesses; they quietly support some of the most advanced medical procedures.

“Joint replacements, heart surgeries, organ transplants all rely on antibiotics to prevent dangerous infections. Chemotherapy patients, whose immunity is low, survive because antibiotics protect them from everyday microbes. Remove this safety net, and suddenly these sophisticated treatments become far riskier, even impossible,” explained Dr. Sunil Havannavar Senior Consultant - Internal Medicine, Manipal Hospital Sarjapur to IndiaTV.

How Does Antimicrobial Resistance Spread?

Antibiotic resistance doesn’t arrive with a bang. It builds slowly, every time antibiotics are misused—taken for viral infections, stopped halfway through, used without prescription, or demanded unnecessarily for fevers. Each misuse gives bacteria an opportunity to evolve. Doctors are already seeing cases where high-power, last-resort antibiotics are needed for infections that should have been easily treatable.

In fact, a new global study in The Lancet’s eClinicalMedicine has drawn serious concern about the sharp rise of antimicrobial resistance (AMR) in India, placing the country at the centre of what many specialists now consider a fast-moving superbug crisis. The research, titled Preprocedural screening for multidrug-resistant organisms in endoscopic retrograde cholangiopancreatography: an international, multicentre, cross-sectional observational study, shows that Indian patients had the highest worldwide rates of multidrug-resistant organisms (MDROs) among those undergoing a common endoscopic procedure.

A superbug is a strain of bacteria that no longer responds to one or more groups of antibiotics that previously worked well. This can happen through enzyme production such as carbapenemases, changes in drug targets, increased pumping out of drugs or shifts in the cell wall that block antibiotics from entering, as per National Institute of Health. When bacteria gain resistance to several antibiotic classes, the list of possible treatments becomes very small. Such resistance makes infections tougher to manage because routine medicines no longer work, leading to more severe illness.

What We Can Still Do to Stop This Future

The situation is serious, but not irreversible. We can slow the rise of resistance if everyone plays their part.

• Doctors can prescribe antibiotics only when necessary.
• Patients can avoid demanding them for every fever or throat ache.
• Everyone must finish the full antibiotic course when prescribed.
• Hospitals can strengthen hygiene and infection control.
• Farmers can limit antibiotic use in livestock.
• Scientists can continue developing new medicines and vaccines.

Magnesium and melatonin are both popular supplements, especially among people looking to get more shuteye, but can combining them improve your sleep? Some research indicates that taking magnesium and melatonin together could improve sleep quality, though stronger, larger studies are needed to confirm the effect.

Can We Combine Magnesium and Melatonin To Support Sleep?

Studies on using magnesium and melatonin together are limited, but some evidence suggests it could benefit sleep in certain individuals.

Also Read: China’s ‘Zombie Cell’ Pill Claims To Extend Human Life To 150—Could It Work?

As per Health, one study focusing on women with polycystic ovary syndrome found that taking both magnesium and melatonin improved sleep quality. Another study reported that people with sleep difficulties who used a combined magnesium-melatonin supplement for four weeks noticed modest improvements in how well they slept.

The exact reason why the two work together is not completely understood, but magnesium and melatonin may influence each other in a way that supports sleep.

“Magnesium does have an effect on melatonin levels,” said Marie van der Merwe, PhD, coordinator of the applied physiology and nutrition doctoral program at the University of Memphis, speaking to Health. “The amount of magnesium you have can influence how well your body produces melatonin.”

You don’t necessarily need to take the two supplements at the same time to benefit, van der Merwe noted. It’s fine to take magnesium in the morning and melatonin before bed.

The takeaway: There could be a link between magnesium and better sleep, but more research is needed to be sure.

Magnesium And Sleep

Magnesium is a vital mineral that supports nerve and muscle function, regulates blood pressure and blood sugar, and contributes to the formation of bone, protein, and DNA. As per Mayo Clinic, it is also commonly taken to help with sleep, but it is not without risks.

Benefits of Magnesium for Sleep

Some studies suggest magnesium may help sleep by:

Improving sleep quality: Ensuring adequate magnesium through diet or supplements may help people with deficiencies sleep better and ease anxiety.

Reducing muscle tension: Magnesium can help relax muscles and relieve tension, which can make it easier to fall asleep.

Risks of Magnesium for Sleep

Research on magnesium for sleep is limited. Supplements aren’t regulated by the FDA for safety or effectiveness and carry potential risks:

Delayed effect: It may take several weeks before magnesium supplements noticeably improve sleep.5

Side effects: High doses can cause diarrhea, nausea, and stomach cramps.7

Drug interactions: Magnesium can interfere with some medications, reducing their effect or increasing side effects. Talk to a doctor before starting any new supplement.7

Melatonin And Sleep

Melatonin is a well-known sleep aid, though it’s actually a hormone your body naturally produces to regulate sleep-wake cycles.⁸ “Melatonin is in charge of running the [internal] clock, and it really is important for regulating your circadian rhythms,” van der Merwe said.

Benefits of Melatonin for Sleep

Works quickly when needed: Unlike magnesium, melatonin can act soon after taking it, making it useful for occasional sleepless nights.

May help you fall asleep faster: Studies show that a 2-milligram dose of melatonin helped some people fall asleep about nine minutes sooner than placebo.

Supports sleep timing: Melatonin can help shift workers, travelers with jet lag, or those with irregular sleep schedules align their sleep patterns.

Risks Of Melatonin For Sleep

Melatonin can help with some sleep difficulties but won’t fix all sleep disorders, van der Merwe said. Like magnesium, melatonin isn’t FDA-regulated:

Long-term effects unclear: There’s limited data on the safety of long-term melatonin use.

Medication interactions: Melatonin may interact with antibiotics, antidepressants, and birth control.

Caution for certain groups: It’s generally not recommended for children or people with dementia, and should be used carefully by those with seizures or on blood thinners.

What to Consider Before Taking Magnesium and Melatonin Together?

It’s wise to speak with a healthcare professional before starting any new supplements, alone or in combination.

Van der Merwe emphasized that sleep problems can stem from issues that supplements alone won’t fix. Conditions like cardiovascular disease, type 2 diabetes, and depression can affect sleep.

If you want to try one or both supplements, a doctor can help determine the best timing for magnesium, melatonin, or a combined product.

“Melatonin [should] increase at night,” van der Merwe explained, so it is crucial to take it at the right time. Taking it in the morning can disrupt your internal clock.

Even though sleep-support supplements like magnesium and melatonin have grown in popularity, it’s important to consult a professional to see if they will help in your situation.