Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
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The NHS has released updated guidance for people who are currently taking clonazepam, a commonly prescribed medicine that belongs to the benzodiazepine group. According to the health service, clonazepam is often used to control seizures or fits linked to epilepsy, ease involuntary muscle spasms, and help manage panic disorders. It is also prescribed in some cases for people with restless legs syndrome (RLS). NHS Inform notes that “around 1 in 10 people experience restless legs syndrome at some stage in their life.”
Explaining how the drug works, the NHS says it increases levels of gamma-aminobutyric acid (GABA), a chemical in the brain that has a calming effect. By boosting GABA, clonazepam can reduce anxiety, prevent seizures or fits, and relax tight or overactive muscles.
Clonazepam is only available on prescription and comes as tablets or a liquid. Most adults aged 18 and over can take either form. In certain cases, children as young as one month old may be prescribed clonazepam to treat epilepsy, as per NHS.
That said, there are situations where extra caution is needed. People who are due to have surgery or dental treatment, those who are pregnant, trying to conceive, or who have sleep-related conditions may be advised to stop taking the medicine. However, these are not the only groups the NHS says should be careful.
Clonazepam is not suitable for everyone. Before starting treatment, patients are advised to tell their doctor if they:
Like many medicines, clonazepam can cause side effects. Common effects, which affect more than 1 in 100 people, include disturbed sleep such as vivid dreams, feeling sleepy during the day, light-headedness, dizziness, unsteadiness, and muscle weakness.
When it comes to long-term use, the NHS warns that clonazepam can lead to withdrawal symptoms if taken for a prolonged period. Because of this risk, people who have been prescribed the drug for more than four weeks may have their dose reduced slowly when stopping treatment, rather than stopping suddenly.
The NHS also stresses that this is not a complete list of side effects. Patients are advised to read the information leaflet that comes with their medicine for full details.
Although uncommon, some people may experience serious side effects while taking clonazepam. The NHS advises contacting a doctor or calling 111 immediately if you notice:
In rare cases, clonazepam can trigger a serious allergic reaction known as anaphylaxis.
Disclaimer: This article is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified doctor, pharmacist, or healthcare provider before starting, stopping, or changing the dosage of any medication.
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Every winter, people in Delhi prepare themselves for stinging eyes, tight chests and coughs that refuse to go away as thick smog blankets the city. Now, fresh research from Jawaharlal Nehru University (JNU) suggests there is another hidden danger in the polluted air. According to the study, Delhi’s winter smog may also be carrying antibiotic-resistant bacteria, adding to health worries in one of the most polluted cities on the planet.
The research, titled Distribution and antibiotic resistance patterns of airborne staphylococci in urban environments of Delhi, India, was published in Nature – Scientific Reports. It found disturbingly high levels of antibiotic-resistant “superbugs” in both indoor and outdoor air across the city, particularly in winter when pollution levels spike. The findings point to polluted air acting as a possible vehicle for antimicrobial resistance (AMR), which experts already consider one of the gravest global health threats.
As per Indian Express, to understand what people might be breathing in, the researchers collected air samples from a range of everyday locations across Delhi, such as:
Both indoor and outdoor air samples were taken during summer, monsoon and winter to track how bacterial levels and resistance patterns shifted with the seasons.
Across every setting, airborne bacteria levels were far above the World Health Organization’s recommended safe limit for microbial exposure. In some winter samples, bacterial counts exceeded 16,000 colony-forming units per cubic metre, which is more than 16 times higher than the WHO guideline.
What raised even greater concern was the type of bacteria detected. Many belonged to the Staphylococcus group, which includes strains linked to skin infections, pneumonia, bloodstream infections and illnesses commonly acquired in hospitals.
According to the researchers, a large share of the airborne bacteria were identified as methicillin-resistant staphylococci (MRS), meaning they do not respond to commonly prescribed antibiotics. Among these:
Notably, 14 out of 36 multidrug-resistant samples carried the mecA gene, a well-known marker that makes bacteria resistant to methicillin and related antibiotics.
The study showed that levels of airborne drug-resistant bacteria were highest in winter, while monsoon rains led to a sharp drop in outdoor contamination.
Researchers point to a few likely reasons:
On the other hand, rainfall during the monsoon appears to clear bioaerosols from the air, reducing bacterial concentrations outdoors.
Many healthy people may breathe in these bacteria without becoming sick. However, the risk is much higher for:
The researchers note that inhaling drug-resistant bacteria does not automatically lead to infection. Still, it raises the risk of infections that are harder to treat, especially if the bacteria manage to enter vulnerable parts of the body.
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Researchers say consuming excessive short-form videos on social media may lead to 'brain rot' and cause cognitive decline, increase the risk of depression and worsen behavior in young children and adults.
Named as the 2024 Oxford University Word Of The Year, 'brain rot' is defined as the supposed deterioration of a person’s intellectual state due to overconsumption of low-quality online content such as TikTok videos, Instagram reels and YouTube Shorts.
Until now, brain rot was considered to be merely internet slang but now multiple studies show that the condition can, indeed, impact overall brain health and pave the way for neurodegenerative diseases.
According to a literature review published in Psychological Bulletin, a journal of the American Psychological Association, scientists found links between heavy consumption of such videos and increased symptoms of depression, anxiety, stress and loneliness.
Additionally, the September 2025 study also found that extreme intake of short form videos (SFVs) can worsen cognitive functioning and weakening emotional control as well as regulation.
Moreover, an October 2025 study from Capella University, Minneapolis which summarized 14 studies on SFVs discovered that people who regularly watch videos, ranging between 15 to 60 seconds, were prone to developing 'TikTok Brain' and suffered from low attention spans.
The review noted, "Reports from educators and parents describe teens struggling to focus in class or during prolonged tasks, behavior changes often attributed to constant stimulation from social media scrolling."
Based on these results, Keith Robert Head, a doctoral student in social work at Capella University and study author commented, "So one of the questions that would be interesting for researchers to study is: Are these ADHD diagnoses actually ADHD, or is it an impact from the continued use of short-form video?"
James Jackson, a neuropsychologist at Vanderbilt University Medical Center told NBC News, "The narrative that the only people who are worried about this are grumpy old grandpas who are yelling at you to get off their lawn or the idea that if you’re concerned about this you’re not in step with the times, I think that’s really simplistic."
He also noted that SFVs can be useful through the opportunities it creates for learning as well as community-building and social media users should seek to maintain a balance.
“There are people that engage with short-form videos in ways that are value-added, for sure. But if their engagement is pulling them away from other, more healthy opportunities, if it is isolating them from other people, if it is creating situations where they’re less and less likely to just sit around and be bored, I think that’s a problem," he said.
She further noted that it may take many years of study to determine whether cognitive changes associated with SFVs consumption are reversible and whether they can qualify as an 'addiction'
“It might be too early to claim universal doom,” Gupta said. “The research for alcohol, cigarettes and drugs took 75 years or more to develop. But I would be surprised if, in the next five to 10 years, we do not have similar signs validating the moral panic that we have around short-form videos.”
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