Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

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Implant Dentistry Beyond Replacement: How It Restores Quality of Life

Updated Jun 15, 2026 | 06:00 PM IST

SummaryBy restoring the ability to eat, speak, smile, and engage confidently in daily life, implant dentistry offers benefits that extend far beyond the replacement of a missing tooth.
dental implant (1)

As awareness of the broader benefits of implant therapy continues to grow, dental implants are increasingly being recognised as a comprehensive rehabilitation solution. (Photo credit: AI generated)

The loss of a tooth is often viewed as a purely dental concern, but its impact extends far beyond appearance. Missing teeth can affect chewing efficiency, speech, facial structure, and even emotional well-being. While traditional tooth replacement options have served patients for decades, modern implant dentistry has transformed the way tooth loss is managed. Today, dental implants are not merely about filling a gap; they are about restoring function, confidence, and overall quality of life.

Restoring Natural Function and Comfort

Dr. Achuth M. Baliga, Director, Happiest Pearls, said, "One of the greatest advantages of dental implants is their ability to closely replicate the function of natural teeth. Unlike removable dentures that may shift or cause discomfort, implants are anchored securely within the jawbone, providing exceptional stability. This allows individuals to chew a wider variety of foods with confidence and comfort."

The expert went on to say that proper chewing is essential for nutrition and digestive health. Patients who struggle with missing teeth often avoid certain foods such as fruits, vegetables, nuts, and proteins, potentially compromising their dietary intake. By restoring full chewing efficiency, dental implants help individuals maintain a balanced and nutritious diet, contributing to better overall health. Dr Baliga also answered more FAQs on the subject.

Preserving Jawbone and Facial Structure

Tooth loss triggers a process known as bone resorption, where the jawbone gradually deteriorates due to the absence of stimulation from the tooth root. Over time, this can lead to changes in facial appearance, including a sunken or prematurely aged look.

Dental implants address this challenge by functioning like artificial tooth roots. They stimulate the surrounding bone during everyday activities such as chewing, helping to preserve bone volume and density. This not only supports long-term oral health but also helps maintain natural facial contours. In many cases, implants play a significant role in preserving a youthful appearance and preventing the structural changes associated with prolonged tooth loss.

Rebuilding Confidence and Self-Esteem

The psychological effects of missing teeth are often underestimated. Individuals may become self-conscious about smiling, speaking, or interacting socially. Concerns about appearance can affect personal relationships, professional interactions, and overall self-confidence.

Dental implants provide a fixed and natural-looking solution that blends seamlessly with surrounding teeth. The ability to smile without hesitation and speak without worrying about movement or instability can have a profound impact on emotional well-being. Many patients report feeling more confident in social settings and more comfortable expressing themselves after completing implant treatment.

Supporting Better Speech and Daily Living

Missing teeth, particularly in the front of the mouth, can interfere with pronunciation and speech clarity. Similarly, loose or ill-fitting dentures may cause slurring or difficulty articulating certain sounds.

Because implants are securely integrated into the jawbone, they provide the stability needed for clear and natural speech. Everyday activities such as eating in public, participating in meetings, or engaging in conversations become more comfortable and predictable. These seemingly small improvements can significantly enhance daily living and social participation.

Advancements Making Treatment More Predictable

Modern implant dentistry has benefited greatly from technological innovations. Digital imaging, three-dimensional treatment planning, guided implant placement, and advanced restorative materials have improved precision and predictability. These advancements allow clinicians to tailor treatment plans to each patient's unique anatomy and functional requirements.

In addition, improved understanding of bone biology and soft tissue management has contributed to higher success rates and more aesthetically pleasing outcomes. As a result, implant therapy has become a reliable long-term solution for a wide range of patients experiencing tooth loss.

A Comprehensive Approach to Oral Health

Implant dentistry today is centred on patient outcomes rather than simply replacing missing teeth. The goal is to restore oral function, maintain facial structure, support emotional well-being, and improve overall quality of life. Successful treatment considers not only the clinical aspects of tooth replacement but also the patient's lifestyle, expectations, and long-term health needs.

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Are Your Knees Ageing Faster Than You?

Updated Jun 15, 2026 | 05:51 PM IST

SummaryIn India, the incidence of obesity is on a steady rise. Could it be responsible for knee problems?
Knee pain

Knee pain is becoming a common concern among people across age groups. (Photo credit: AI generated)

India has a physical inactivity problem that is contributing to a growing burden of joint and musculoskeletal disorders among its working-age population. Close to half of Indian adults were insufficiently active in 2022, according to a Lancet study, and among women, that figure climbed to 57%. Behind those numbers is a generation whose muscles have quietly stopped supporting their joints and whose weight has quietly started punishing them for it.

Also Read: Can A Heatwave Affect The IVF Process In A Lab?

Why do Indians struggle with weak, ageing knees?

In an interview with Health and Me, Dr Deepak Gautam, Sr. Consultant Orthopaedic & Robotic Joint Replacement Surgeon, Apollo Hospitals, Navi Mumbai, explained how a patient's knees can start ageing faster than their actual biological age.

Young Indians broadly assume joint problems are inherited with age. Clinical practice keeps demonstrating that they are earned much earlier, through years of small daily choices that never feel consequential until they are. The best time to address this is before a patient ever needs to describe where it hurts.

The knee absorbs roughly four times a person's body weight with every step. Add excess weight over several years, and that force erodes cartilage far ahead of schedule. Obesity also drives systemic inflammation through the release of molecules from fat tissue, which attack joint cells independently of any mechanical load. Patients frequently describe their pain as having an insidious onset and, at times, being sudden. Clinically, joint degeneration develops gradually over many years before symptoms become apparent.

Read more: Feeling Weak In Your Knees? Here Are Tips To Maintain Them As You Age

What are the consequences of weak knees?

Muscle weakness makes that threshold arrive sooner. The quadriceps and core do the work of absorbing shock and stabilising the joint under load. Sedentary work strips that capacity away gradually, and screen time beyond three hours a day has been directly linked to weight gain and metabolic deterioration. For a large portion of India's urban workforce, three hours of daily screen exposure is where the morning starts.

None of this stays contained to the joints. Around one in five Indian adults is already managing several chronic conditions at once, and 45.4% of Indians with coronary heart disease remain physically inactive. Musculoskeletal decline and cardiovascular disease tend to share the same lifestyle roots and reinforce each other. Globally, inactivity rates are still climbing and are expected to reach 35% by 2030, up from 31% in 2022.

When should you take action?

Once cartilage degeneration starts, it is very difficult to reverse the process. We can, however, retard the progression of the disease or prevent it from occurring in the first place. That single fact should change how people think about when to seek help. By the time climbing stairs or a regular walk in the market or garden becomes painful, the window for conservative management has already narrowed.

Waiting for symptoms is the wrong strategy. People with sedentary work patterns, weight above the healthy range, or significant screen exposure should have their joint mobility, gait, and muscle strength assessed before pain enters the picture at all. Resistance training twice a week, clinician-guided weight management, and dietary changes that dial down chronic inflammation are not complicated prescriptions. They are what separates someone who stays mobile in their forties from someone who is discussing surgical options.

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Can A Heatwave Affect The IVF Process In A Lab?

Updated Jun 15, 2026 | 01:00 PM IST

SummaryA large number of patients are reaching out to fertility consultants regarding how heatwaves can affect the IVF labs.
IVF Heatwave

Extreme heat can lead to a great deal of discomfort, even dehydration. (Photo credit: AI generated)

Many couples are battling infertility and are keen on opting for ARTs to conceive and fulfill the dream of parenthood. However, the country continues reeling under severe heatwave conditions. Currently, a large number of couples who are planning fertility treatments are becoming stressed regarding how heatwaves can impact IVF procedures and even the success rates. Patients frequently ask fertility consultants whether extreme outdoor heat can affect the IVF laboratory environment, embryos, sperm samples, or even egg quality. However, there is no need to panic, as labs are designed to function even under highly controlled conditions throughout the year, and it is possible for couples to conceive successfully.

In an interaction with Health and Me, Dr. Aswati Nair, Fertility Specialist, Nova IVF Fertility, Rajouri Garden, Delhi, spoke about how extreme temperatures can affect the IVF process and what the consequent impact is on the outcome.

Read more: Heatwaves And Toxic Air Create A Growing Health Crisis In Delhi

Does a heatwave affect the IVF lab?

Usually, all the IVF labs have Air Handling Units (AHUs), which maintain the internal condition of the lab throughout the year at the same condition and temperature, and all the parameters are maintained throughout the year with the help of this equipment and gadgets. So, the internal environment of the lab does not get affected by an external heatwave. Understand that the temperature-sensitive procedures that are carried out inside the IVF lab, such as handling eggs, sperm, and embryos, are performed in a controlled setting and are monitored constantly. Hence, external heatwaves do not directly impact the IVF lab environment or the development of embryos. But only from the patient's perspective; they need to be hydrated and careful when there is scorching heat outside.

Too much heat can lead to dehydration, weakness, fatigue, dizziness, and stress, which can impact the patient’s health during fertility treatment. Women undergoing IVF cycles are put on hormonal medications, and staying hydrated is necessary for everyone. It is the need of the hour for the patients to take charge of their well-being right away!

Read more: Heatwave In India: Temperatures Continuously Rising; Stay Hydrated, Says PM Modi

Precautions to take

The precautions that patients can take are to stay well-hydrated and adhere to a balanced diet with lots of fruits and seasonal fruits like watermelon and muskmelon, which can improve hydration. They can have coconut and lemon water and avoid beverages, carbonated drinks, caffeine, and alcohol. They can follow these crucial tips to stay healthy during the heatwave. Patients should be sure to follow the guidelines given by the fertility consultant.

Even if the heatwaves can lead to discomfort, it doesn’t affect the functioning of modern IVF laboratories. By paying attention to various factors such as hydration, nutrition, and self-care, patients can safely continue their fertility journey even if there is extreme heat outside.

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