Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

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From Better Sleep To Stronger Bones: Here’s How Magnesium Can Help Boost Your Health

Updated Apr 22, 2026 | 04:00 AM IST

SummaryMost people get enough magnesium from food, but certain groups are more vulnerable to deficiency. These include people with gastrointestinal disorders such as Crohn’s disease or coeliac disease, those with type 2 diabetes, people who consume excessive alcohol, and older adults.
From Better Sleep To Stronger Bones: Here’s How Magnesium Can Help Boost Your Health

Credit: Canva

Magnesium is an essential mineral that plays a crucial role in over 300 biochemical reactions in the body. From regulating muscle and nerve function, to supporting a healthy immune system, to building protein, maintaining blood sugar and blood pressure levels, and aiding in energy production, magnesium plays an important role in our health.

Importantly, it helps in getting a good night’s sleep by promoting relaxation, calming the nervous system, and helping your body produce melatonin, the so-called sleep hormone. Magnesium supplements are among the most popular dietary supplements in America, the Washington Post reported.

“There’s a lot of interest in magnesium right now — all of my patients are asking me about it,” Bethany Marie Doerfler, a clinical research dietitian at the Northwestern Digestive Health Center, was quoted as saying.

“There’s a lot of insomnia in the United States, and many of my patients are saying, ‘Can I use magnesium, can it be helpful?’”

Studies have proven that high levels of magnesium in the diet can lower the risk of heart disease and strokes. It also increases bone mineral density, protecting against fractures and osteoporosis.

Yet despite its well-documented benefits, researchers have found that a majority of people consume less magnesium than the recommended amounts.

How Much Magnesium Do You Need?

According to the American health officials, women aged between 19 and 30 should consume 310 milligrams of magnesium daily (350 milligrams if they’re pregnant), and 320 milligrams if they are 31 or older.

For men, the recommendation is that they consume 400 milligrams if they’re 19 to 30 years old, and 420 milligrams if they’re 31 or older.

Doerfler noted that one can get plenty of magnesium simply by eating a few daily servings of the right plant foods.

According to the National Institutes of Health some top dietary sources of magnesium, include

  • Pumpkin seeds
  • Chia seeds
  • Almonds
  • Spinach,
  • Cashews
  • Peanuts
  • Shredded wheat cereal
  • Soymilk
  • Black beans

Who Is At Risk Of Magnesium Deficiency?

Most people get enough magnesium from food, but certain groups are more vulnerable to deficiency. These include people with gastrointestinal disorders such as Crohn’s disease or coeliac disease, those with type 2 diabetes, people who consume excessive alcohol, and older adults.

If you’re low on magnesium, you might notice symptoms such as muscle twitches, spasms, fatigue, low appetite, nausea, or an irregular heartbeat. However, the only way to confirm a deficiency is through a blood test prescribed by your doctor.

Can Magnesium Supplements Really Help?

While magnesium deficiency can lead to cramps, most cases of muscle cramps are not due to low magnesium. Research shows limited evidence that supplements prevent cramps, especially in older adults.

The link between magnesium and better sleep is also unclear. Some studies found it helped people fall asleep faster, while others found no significant difference.

When it comes to migraines, evidence is stronger. Studies suggest that taking 122–600 mg of magnesium daily for 4–24 weeks may reduce the frequency and severity of migraines in some people.

Are Magnesium Supplements Safe?

In general, magnesium supplements are safe when taken in the recommended amounts. However, too much can lead to nausea, abdominal cramps, and diarrhea, because magnesium draws water into the intestines.

Taking extremely large doses (around 5,000 mg daily) can cause magnesium toxicity, which is dangerous. Always check with your doctor before starting supplements, especially if you take other medications.

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31-Year-Old Brazilian Beauty Queen Dies of Heart Attack: Why Young Adults Are At High Risk

Updated Apr 21, 2026 | 10:00 PM IST

SummaryDoctors are now seeing more heart attack cases in people as young as their late 30s and early 40s. The experts noted that people mistake early signs for lifestyle issues: acidity after a heavy dinner, shoulder pain from sitting at a laptop, or tiredness from long hours.
31-Year-Old Brazilian Beauty Queen Dies of Heart Attack: Why Young Adults Are At High Risk

Credit: Daily Mail

A 31-year-old Brazilian beauty queen, Maiara Cristina de Lima Fiel, has reportedly died after suffering a sudden heart attack.

de Lima Fiel, a young mother, was due to compete in a beauty pageant next week. She reportedly had no major health issues. Paramedics spent more than an hour trying to save her life but she tragically did not recover, The Daily Mail reported.

Her untimely death has sparked grief and shock among her community and followers, and has also reignited concerns over unexpected cardiac events in seemingly healthy individuals.

Who Was Maiara Cristina de Lima Fiel?

de Lima Fiel was crowned Miss Londrina last year in a prestigious regional beauty pageant and also came runner-up in the 2025/26 edition of Miss Sarandi, The Daily Mail reported.

"She was such a committed, dedicated young woman," the report quoted Vitor Tavares, organizer of the contest Maiara, as saying. She was due to compete on April 29.

"I had the pleasure of meeting her in person at the end of last year when she confirmed her participation as Miss Londrina. From that moment, it was clear how seriously she took this dream," he added.

While detailed medical circumstances have not been publicly disclosed, such sudden cardiac events in young adults are often linked to underlying, sometimes undiagnosed, heart conditions or acute cardiovascular episodes.

Also read: US Cardiologist Explains Why 2026 AHA Cholesterol Guidelines Recommend Starting Young

Heart Attacks Rising Among Younger Adults

Acute coronary syndromes, or heart attacks, are on the rise among young adults.

While there are some genetic predispositions for premature heart attacks, the majority of the risk is attributed to the increased incidence of conventional risk factors in young people, such as

  • Obesity,
  • Sedentary lifestyle,
  • Diabetes,
  • Hypertension,
  • Dyslipidemia
  • Smoking
  • Substance abuse.
Lesser-discussed, unconventional risk factors, such as mental stress, workplace stress, and environmental pollution, are also contributing significantly to this silent epidemic.

Who Is At Risk for Sudden Heart Attacks?

Also read: Ideal Blood Pressure Reading for Older Adults: Harvard Health Experts Have an Answer

Doctors are now seeing them in people as young as their late 30s and early 40s, especially those with high-stress jobs.

“They mistake early signs for lifestyle issues: acidity after a heavy dinner, shoulder pain from sitting at a laptop, or tiredness from long hours," Pankaj Vinod Jariwala, Interventional Cardiologist at Yashoda Hospitals, told HealthandMe.

Dr Krunal Tamakuwala, cardiologist at KD Hospital, Ahmedabad, pointed out that the real danger is not that these heart attacks are completely "symptomless," but that their symptoms are so common that they are easily ignored.

By the time a person finally sees a doctor, their heart may already be seriously damaged.

“Sometimes, it arrives silently, hidden behind complaints we consider minor. That is why doctors urge patients not to ignore symptoms that linger or feel unusual, even if they seem harmless at first,” Dr Tamakuwala told HealthandMe.

How To Reduce Heart Disease Risk In The 30s?

The experts shared that to boost heart health, the key is to

  • Eat a healthy and balanced diet
  • Avoid refined sugars, fats, and processed foods.
  • Do at least 30 minutes of moderate physical activity per day, for five days a week.
  • Stay away from smoking,
  • Early screening and treatment
  • Improving mental health.

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Heatwave Hassles: What Body Odour Could Say About Your Health

Updated Apr 21, 2026 | 09:00 PM IST

SummaryA heatwave can lead to excessive perspiration, and body odour could be indicative of underlying health problems.
Heatwave

Amid the ongoing heatwave, an expert spoke about what body odour indicates about health. (Photo credit: iStock)

Body odour is natural, but sometimes it may signify a health issue. When body odour is persistent, unusual, and/or changes suddenly, it could indicate a possible health problem. Sweat itself is odourless, but when it interacts with bacteria on the skin, it creates the odour that we associate with body odour. Some of the factors that may alter the way the body smells are medications, hormones, and lifestyle choices. Dr Pooja Kanumuru, a dermatologist at Apollo Clinic, Indiranagar, addressed this for Health and Me.

What does body odour indicate?

There are medical conditions that can cause body odour to be unusual or excessive: bromhidrosis; bacterial and/or fungal skin infections; and systemic diseases such as diabetes, liver disease, and kidney disease. For example, a diabetic with poor management may have a fruity-smelling body odour, whereas an infected person may have a foul body odour due to bacterial activity.

Body odour becomes an issue when there is no improvement despite proper hygiene. If body odour is associated with other symptoms such as fatigue, unexplained weight loss, fever, and/or abnormal skin changes, these should be addressed to determine the cause and seek appropriate assistance. Medically associated body odour does not decrease with normal methods such as bathing and/or the use of deodorants but tends to persist.

Factors that affect body odour

Body odour can also be affected by the following:

Hormonal and metabolic changes during certain periods of life (for example, puberty, menstruation, pregnancy, and menopause) can change the amount of sweat produced, which can also alter the intensity of its smell.

Thyroid disorders, especially hyperthyroidism, can sometimes result in increased sweating.

Rare metabolic disorders, such as trimethylaminuria, can result in a strong, fishy-smelling body odour due to the inability to break down certain substances in the body.

Clinical insights of body odour

It is interesting how certain unusual odours can offer important clinical insights. For example, if a person has a fruity odour, this could indicate difficulties with diabetes control. A fishy smell could be a sign of a metabolic disorder, while an ammonia-like smell may indicate problems with kidney function. Meanwhile, musty or foul odours may suggest an infection or liver dysfunction. While these odours cannot be used as stand-alone diagnoses, they can help guide further medical evaluation.

Lifestyle changes to improve body odour

Diet and lifestyle choices significantly affect body odour. For example, foods such as garlic, onions, spicy foods, red meat, and alcohol can exacerbate body odour, while poor hydration, high stress levels, smoking, and obesity can worsen it further. Additionally, wearing very tight or non-breathable clothing may cause perspiration and bacteria to become trapped, thereby worsening body odour.

Keeping your body clean, applying the right type of antiperspirant, wearing breathable materials, and maintaining a healthy diet can all help in managing body odour. However, if body odour persists or worsens, you should consult a doctor. A prompt medical assessment can identify the cause and allow your physician to discuss possible treatments, including topical medications and procedures that reduce excessive sweating.

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