Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

End of Article

Do You Have Persistent Itching? It Could Be Linked To These 4 Cancers

Updated Jan 9, 2026 | 09:00 PM IST

SummaryPersistent itchy skin is usually harmless, but doctors warn it can sometimes be linked to certain cancers. Here are four types where itching may be an early sign. Keep reading for details.
persistent itching cancer

Credits: Canva

Itchy skin is something most of us deal with occasionally, and in many cases, it is harmless. Everyday triggers such as rough clothing, insect bites, or dry winter air can all leave the skin irritated. Itching is also commonly linked to skin conditions like eczema or psoriasis.

That said, an oncologist has pointed out that persistent itching can, in some cases, be linked to certain cancers. In a TikTok video, Dr Amit Garg, a cancer specialist based in California, explained that itching can appear as a symptom in four specific types of cancer. While itching alone is not usually a cause for concern, it may become more meaningful when it occurs alongside other symptoms that should be checked by a GP.

1. Hodgkin Lymphoma

Hodgkin lymphoma is a relatively rare cancer that affects lymphocytes, the white blood cells that help the body fight infection. Dr Garg explained that this cancer can cause “severe, widespread itching,” which often becomes worse at night. The NHS also lists itchy skin as a possible symptom, along with:

  • A painless lump or swelling, usually in the neck, armpit, or groin, which is the most common sign
  • Pain in the glands of the neck, armpit, or groin after drinking alcohol
  • A high temperature
  • Night sweats
  • Shortness of breath
  • Sudden, unexplained weight loss

The NHS advises seeing a GP if you notice any of these symptoms. Although they are common and do not always point to Hodgkin lymphoma, it is important to rule it out. Early diagnosis improves the chances of successful treatment, so symptoms should not be ignored.

2. Polycythemia Vera

Polycythemia vera is a rare, slow-developing blood cancer. According to the NHS, it is most often caused by a change in the JAK2 gene, which leads the bone marrow to produce too many red blood cells. An increased concentration of red blood cells is known as erythrocytosis, although having this condition does not automatically mean cancer.

One symptom of erythrocytosis can be itchy skin, particularly after bathing or showering. You should speak to a GP if symptoms persist. Other signs may include:

  • Headaches
  • Blurred vision
  • Reddened skin, especially on the face, hands, and feet
  • Tiredness
  • High blood pressure
  • Dizziness
  • Discomfort in the abdomen
  • Confusion
  • Bleeding issues such as nosebleeds or bruising
  • Gout, which can cause joint pain, stiffness, and swelling

3. Gallbladder And Pancreatic Cancer

Gallbladder cancer and pancreatic cancer often share similar symptoms. These can include a reduced appetite, unintentional weight loss, fever, nausea, and changes in bowel habits such as diarrhoea or constipation.

Dr Garg explained that both cancers can cause “intense itching,” which happens when bile salts build up under the skin. The NHS also lists itching as a symptom for both conditions, noting it may occur alongside darker urine, paler stools, and jaundice, which can cause yellowing of the skin or the whites of the eyes.

One key difference between the two cancers is the type of pain experienced. Gallbladder cancer may cause a dull ache on the right side of the abdomen, while pancreatic cancer more commonly causes pain in the upper abdomen and back, which can worsen after eating or when lying down.

In both cases, you should see a GP if symptoms last longer than two weeks or if you have lost weight without trying. You should call 111 if vomiting lasts more than two days, diarrhoea continues for more than seven days, or if your skin turns yellow.

4. Cutaneous T-cell Lymphoma

Cutaneous T-cell lymphoma is a form of skin lymphoma and a rare type of non-Hodgkin lymphoma. It begins in the T cells of the skin and often appears as flat, red patches that may be itchy.

In its early stages, these patches can resemble common skin conditions such as eczema or psoriasis. Seeing a GP is important if symptoms develop, as they can assess whether it is a common skin issue or something more serious.

Cancer Research UK states that around 150 people in the UK are diagnosed with cutaneous T-cell lymphoma each year, making it a rare cancer. As with many cancers, early diagnosis can play a key role in improving treatment outcomes.

End of Article

Are Earphones Slowly Damaging Your Hearing? Early Signs To Watch For

Updated Jan 9, 2026 | 06:00 PM IST

SummaryConstant earphone use can cause noise-induced hearing loss that builds over time and cannot be reversed. Experts explain early warning signs and simple ways to protect hearing.
earphone hearing problem

Credits: Canva

Earphones have slipped into almost every part of daily life. They power music, calls, podcasts, workouts, and long online meetings. What often goes unnoticed, however, is the steady rise of a silent and irreversible condition linked to their misuse: noise-induced hearing loss.

According to the World Health Organisation, more than one billion young people worldwide are at risk of hearing damage due to unsafe listening habits involving earphones and similar devices. Health experts say this is no longer a distant concern but a growing reality, with similar listening patterns being seen across India as well.

What Is Noise-Induced Hearing Loss?

Noise-induced hearing loss, or NIHL, occurs when loud sounds damage the delicate hair cells inside the inner ear. These hair cells play a critical role in transmitting sound signals to the brain. Once damaged, they do not recover or regenerate.

Dr Vinayak Kurle, Consultant ENT at Aster RV Hospital, Bangalore, explains that prolonged exposure to loud audio is one of the most common causes. “The inner ear has a limited number of hair cells. When they are exposed to excessive noise, especially over long periods, the damage can be permanent,” he says.

The generally accepted safe listening level is 85 decibels. Exposure to sound above this level for extended durations significantly increases the risk of hearing loss. Many personal audio devices can easily cross this threshold, especially at higher volume settings.

Early Warning Signs You Should Not Ignore

Hearing damage often develops gradually, which makes it easy to overlook early symptoms. Some of the first signs include:

  • Ringing or buzzing in the ears
  • A blocked, muffled, or distorted sense of hearing
  • Difficulty understanding speech, particularly in noisy environments
  • Ear discomfort after long listening sessions
  • Increased sensitivity to everyday sounds

Dr Kurle notes that many people dismiss these signs as temporary fatigue. “Ignoring early symptoms delays diagnosis and allows the damage to progress,” he says.

Why Delayed Action Can Be Harmful

Untreated hearing loss affects far more than just hearing. Over time, it can contribute to social withdrawal, low mood, reduced concentration, and a decline in work performance. Studies have also linked hearing impairment to cognitive decline when left unaddressed.

What makes NIHL especially concerning is that the damage builds slowly. By the time people realise something is wrong, hearing loss is often already permanent.

How To Protect Your Hearing?

The good news is that noise-induced hearing loss is largely preventable with simple, consistent habits. Avoiding exposure to loud noise remains the most effective step. When loud environments cannot be avoided, protective options such as earplugs, earmuffs, or noise-filtering devices can reduce risk.

Noise-cancelling earphones can also help, as they reduce the need to raise volume in noisy surroundings. Following the WHO’s 60–60 rule is another practical safeguard. This means listening at no more than 60 percent volume for no longer than 60 minutes at a time.

Experts also advise limiting total daily earphone use, keeping volume below 80 decibels, taking regular listening breaks, and scheduling periodic hearing tests. At the first sign of symptoms such as ringing or muffled hearing, consulting an ENT specialist is crucial.

“Hearing loss does not happen overnight,” Dr Kurle says. “It develops quietly over time. Healthy listening habits today are the only way to protect hearing in the long run.”

Preserving hearing requires awareness, restraint, and timely action. In a world filled with constant sound, listening safely may be one of the most important health choices we make.

End of Article

Can Diabetes Increase Your Risk Of Dementia? Doctors Explain The Link

Updated Jan 9, 2026 | 04:00 PM IST

Summary Diabetes and dementia share a strong link, with research showing higher dementia risk in people with diabetes. Our health expert explains how blood sugar affects brain health. Keep reading for details.
diabetes and dementia

Credits: Canva

Due to rising obesity levels, sedentary lifestyles, and a rapidly aging population, type 2 diabetes has become far more common than it was a few decades ago. While high-income countries saw a decline in diabetes-related deaths between 2000 and 2010, this trend reversed from 2010 to 2016. As a result, there has been an overall 5 percent rise in premature deaths linked to diabetes since 2000.

What is especially concerning is that type 2 diabetes is now increasingly diagnosed in children, largely driven by poor diet, excess weight, and lack of physical activity. Beyond its well-known effects on the heart, kidneys, eyes, and nerves, diabetes is also associated with long-term conditions affecting the brain, including dementia.

This raises an important question: how exactly are diabetes and dementia connected? To understand this better, we spoke to Dr Prabhojit Mohanty, Psychiatrist, Sexologist, and De-addiction Specialist, who shared insights on the link.

What Is Diabetes?

Diabetes is a long-term metabolic disorder in which blood sugar levels remain consistently high. This happens either because the pancreas does not produce enough insulin or because the body is unable to use insulin properly. Insulin plays a crucial role in helping glucose enter cells to be used as energy. When this process is disrupted, sugar builds up in the bloodstream, gradually causing damage to vital organs such as the heart, eyes, kidneys, and nerves.

The two main forms are Type 1 diabetes, an autoimmune condition that requires lifelong insulin therapy, and Type 2 diabetes, which is linked to insulin resistance and influenced by lifestyle and genetic factors, according to the Cleveland Clinic.

What Is Dementia?

Dementia refers to a group of symptoms marked by a significant decline in cognitive abilities that interferes with everyday functioning. It affects memory, thinking, reasoning, and decision-making. Dementia is not a single disease but an umbrella term for conditions caused by different underlying disorders, the most common being Alzheimer’s disease.

As dementia progresses, symptoms become more severe, affecting mood, behavior, and the ability to carry out routine activities, often leading to increased dependence on others. Early diagnosis can help slow progression and improve quality of life, as noted by the Alzheimer’s Association.

Diabetes And Dementia: What Is The Link?

An expanding body of research points to a clear association between diabetes and dementia. Large-scale studies and meta-analyses indicate that individuals with diabetes face nearly a 59 percent higher risk of developing dementia compared to those without the condition. This increased risk applies to both Alzheimer’s disease and vascular dementia and tends to rise the longer a person lives with diabetes. From a clinical perspective, several mechanisms are involved. Persistently high blood sugar levels and insulin resistance cause damage to both small and large blood vessels. Over time, this harms the brain’s microvasculature, reducing blood supply and raising the likelihood of strokes and vascular dementia.

Dr Prabhojit Mohanty explained, “When diabetes occurs alongside hypertension, the danger becomes even greater. Both conditions speed up damage to blood vessels in the brain. High blood pressure weakens vessel walls and contributes to plaque formation, which further limits blood flow to the brain. From a biological standpoint, insulin has roles beyond regulating sugar. When the brain becomes resistant to insulin, it affects neuron health, communication between brain cells, and how the brain uses glucose, increasing vulnerability to neurodegenerative conditions such as Alzheimer’s disease.”

Scientists have also introduced the idea of “type 3 diabetes” to describe Alzheimer’s disease as a condition driven by insulin resistance within the brain itself. According to this theory, impaired insulin signalling in neural tissue plays a role in the buildup of amyloid plaques and tau tangles, which are defining features of Alzheimer’s disease. People with diabetes often also struggle with high blood pressure and abnormal cholesterol levels. Together, these factors further raise the risk of dementia and significantly affect the quality of life of both patients and their caregivers. Detecting diabetes early, maintaining good control of blood sugar and blood pressure, and adopting healthier lifestyle habits can go a long way in protecting cognitive function with age.

In simple terms, there is strong clinical and biological evidence showing a clear and well-established connection between diabetes and dementia.

End of Article