Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
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While entrepreneurs debate 70-hour workweeks and professionals continue to slog through long working hours under relentless productivity pressures, basic health needs often take a back seat. The consequences may not be immediately visible, but the body's vital organs quietly bear the burden.
Among them, the kidneys are particularly vulnerable. Poor hydration, irregular eating habits, excessive caffeine intake, lack of sleep, and chronic stress can gradually damage kidney function without causing noticeable symptoms, potentially leading to serious health consequences over time, said experts on the occasion of World Kidney Cancer Day 2026.
World Kidney Cancer Day is observed annually on the third Thursday of June. Spearheaded by the International Kidney Cancer Coalition, the day raises global awareness about the disease, highlights risk factors, and advocates for early detection and patient support.
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The kidneys play a vital role in filtering waste from the blood, regulating blood pressure, maintaining fluid balance, and supporting overall metabolic function.
Speaking to HealthandMe, Dr. L K Jha, Principal Director – Nephrology & Renal Transplant at Yashoda Medicity, pointed out habits such as eating out frequently, inadequate hydration, excessive caffeine consumption, insufficient sleep, and chronic stress that have become routine parts of the workday.
While these behaviors may seem manageable in the short term, they can have significant consequences for kidney health over time. They are also associated with an increased risk of hypertension, obesity, and diabetes, conditions that can gradually impair kidney function. These are also the primary drivers of chronic kidney disease and a significant risk factor for certain kidney cancers.
Dr. Jha emphasized that "kidney diseases are particularly concerning because they often remain asymptomatic until substantial damage has already occurred."
He noted that prioritizing hydration, routine health checkups, regular physical activity, and stress reduction is not only important for maintaining good health but also an investment in long-term well-being and workplace performance.
Dr. Saurabh Shukla, Senior Consultant – Nephrology at Paras Health Gurugram, told HealthandMe that the "fast-paced corporate culture is inadvertently contributing to a growing health crisis, with kidney health emerging as one of its major casualties."
He pointed out that kidney-related conditions often progress silently, with few warning signs appearing until serious damage has occurred. Long hours spent sitting, constant workplace pressure, irregular meal schedules, and dependence on caffeine rather than water are quietly affecting the health of working professionals.
He also highlighted habitual dehydration, high-sodium processed foods, and delayed medical checkups as additional concerns.
From a clinical perspective, Dr. Shukla stressed that early detection is crucial.
"While symptoms such as blood in the urine, persistent lower back pain, unexplained fatigue, or swelling in the legs require prompt medical attention, many kidney conditions are identified incidentally during routine screenings," he said.
The experts underscored that protecting kidney health does not necessarily require drastic lifestyle changes. They suggested simple measures such as:
Dr. Shukla also emphasized the role of employers, suggesting that corporations should implement wellness programs that encourage healthier habits among employees.
In high-stress work environments, he noted, prioritizing kidney health is becoming increasingly important.
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Men often carry the responsibility for their families. They work hard and manage professional pressures to provide the best for their loved ones. Yet, many men tend to neglect their own health, the one thing that makes everything else possible.
Across age groups, men often seek medical attention only when the problem becomes severe or when symptoms become impossible to ignore. The most unfortunate thing regarding health is that many health conditions develop silently for years before showing signs. Taking care of yourselves is not selfish; it is essential. After all, the healthier you are, the better equipped you are to support your family, pursue your goals, and enjoy a fulfilling life for years to come.
One of the best ways to keep an eye on your health is by scheduling regular health screenings. Many conditions, including High BP, Diabetes, high cholesterol, liver disease, and kidney disorders, may not cause noticeable symptoms in the early stages. Annual health checkups can help identify potential problems way before they become serious.
Depending on age and family history, men should also discuss appropriate cancer screenings. Early detection leads to simpler treatment and better outcomes. Make preventive health checkups a routine. Just as a vehicle performs better with regular servicing, your body also needs regular monitoring.
Maintaining muscle mass is equally important for men as they age. Muscle plays a vital role in supporting metabolism. Even though it is important for improving insulin sensitivity, protecting bone health, and maintaining strength. You don’t need rigorous exercise daily.
Strength training two to four days a week is sufficient. It may also help support healthy testosterone levels and reduce the risk of chronic conditions like type 2 diabetes and heart disease. The best thing is that strength training doesn’t require spending hours in a gym. Consistency matters far more than perfection.
We often say that ‘sound mind in a sound body’. This is even true vice versa. Many men feel pressure to appear strong all the time, which can make things difficult. Stress, anxiety, and depression can affect anyone. Persistent fatigue, irritability, difficulty concentrating, or disrupted sleep may be warning signs.
Keep an eye on such changes. Discussion is not a sign of weakness. Talk to trusted family members, friends, or mental health professionals. It can make a significant difference.
Quality sleep is one of the most powerful tools for maintaining good health. Generally, adults need between seven and nine hours of sleep each night. It helps the body to repair tissues, regulates hormones, and supports brain function.
Poor sleep is linked to weight gain, increased stress, and weakened immune function. If your morning is often tiring or you are struggling with insomnia, then discuss it with your healthcare professional. Limit screen time before bed and avoid excessive caffeine late in the day. It can help improve sleep quality.
Heart disease remains one of the leading health risks for men worldwide. The good news is that many cardiovascular risk factors are largely preventable. A healthy weight, physical activity, and a balanced diet can significantly improve heart health.
Avoiding tobacco products and limiting alcohol consumption is also helpful. Add vegetables, fruits, lean proteins, whole grains, and healthy fats to your daily diet. Such a diet can support both heart and overall well-being. Daily brisk walk can help improve BP, cholesterol levels, and cardiovascular fitness.
(By Dr Shivam Sharma, Internal Medicine, Shalby International Hospitals, Gurugram)
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Fever is one of the body's most common warning signals. In most cases, particularly among children, it is caused by a simple infection and resolves within a few days. However, when fever keeps returning repeatedly, follows a pattern, or occurs alongside other concerning symptoms, it may signal an underlying health condition that requires medical attention.
Dr. Hemalata Arora, Director of Internal Medicine at Nanavati Max Super Speciality Hospital, Mumbai, told HealthandMe that a recurring fever refers to repeated episodes of elevated body temperature that are separated by days, weeks, or even months during which a person feels completely well.
While recurrent fevers can sometimes result from common viral infections, especially in children exposed to school environments, daycare settings, or seasonal illnesses, persistent or unexplained episodes warrant further investigation.
The expert stated that understanding the pattern of fever is often one of the most important clues in determining the cause.
Dr. Diksha Goyal, Consultant in Internal Medicine at Marengo Asia Hospitals, Gurugram, told HealthandMe that a recurrent fever can occur when body temperature rises to 38°C or higher and reappears after improving or occurs intermittently over time.
Several medical conditions may cause recurring fever, including:
1. Chronic Infections such as tuberculosis (TB), urinary tract infections
2. Autoimmune Diseases
3. Immune System Disorders
4. Cancers, particularly blood-related cancers
5. Certain Viral Infections
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While recurrent fever is not always dangerous, the experts emphasize that certain accompanying symptoms require prompt medical evaluation.
Dr. Arora notes that urgent attention is needed if recurring fever is associated with:
Dr. Goyal added that persistent cough, swollen lymph nodes, and unexplained body pain can also indicate an underlying condition requiring medical treatment.
These symptoms may point toward serious infections, immune system disorders, blood-related diseases, cancers, or inflammatory conditions in which the body's defense system triggers repeated inflammation without a clear infection.
Another important warning sign is a fever that continues to recur despite treatment. According to Dr. Arora, repeated courses of antibiotics without a confirmed diagnosis should raise concern. In some cases, medications themselves can trigger fever, making a detailed medication history an important part of the evaluation.
The goal is not to panic but to seek timely medical assessment. Check for swollen lymph nodes, rashes, signs of infection, or evidence of systemic inflammation.
The experts noted that early medical evaluation can help identify the underlying cause, prevent complications, and ensure appropriate treatment. With timely diagnosis and proper management, many causes of recurrent fever can be effectively treated, allowing individuals to maintain their health and daily activities.
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