Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
A healthy liver does not ask for much, just the right nutrition. (Photo credit: AI generated)
Many people follow what appears to be a reasonable eating pattern—meals at irregular hours, a light breakfast skipped in the name of time, and dinner pushed late into the evening. Yet the body, particularly the liver, does not respond well to such improvisation. What feels like a manageable routine on the surface can quietly accumulate into something more serious over months and years. The liver needs a consistent flow of nutrients to do its job, which includes managing blood sugar, breaking down fats, and supporting digestion. Long gaps between meals disrupt that rhythm.
Dr Babu U V, Director of R&D, Research & Development Centre, Himalaya Wellness Company, in an interview with Health and Me, spoke about the early symptoms of liver damage and explained how herbs can play a role in reversing it.
Before most people realise that something is wrong with their liver, they may already be experiencing symptoms that indicate potential liver issues. These symptoms may include fatigue, bloating, digestive discomfort, or feeling heavy after eating. Most of the time, these signs are dismissed as minor concerns.
When these issues are ignored or go unnoticed, it becomes difficult to recognise that the liver may be weakened by stress and not functioning optimally. If these problems persist over time, fat can begin to accumulate in the liver, along with other types of metabolic imbalances throughout the body.
To restore balance in the body, small changes in daily habits can lead to significant improvements. For example, eating at regular intervals helps the body maintain a consistent metabolism. Similarly, having lighter dinners and avoiding late-night eating can support better digestion and metabolism of food.
Some herbs commonly used in Indian households and traditional medicine may help support the liver’s healing process, especially when it is under stress.
Each of these herbs works in different ways—some aid digestion, while others help neutralise free radicals and reduce oxidative stress—thereby supporting a healthier lifestyle.
The liver is highly resilient; however, it requires consistent care. An irregular dietary pattern may not affect the liver immediately, but over time it can have a significant impact. Paying attention to simple habits—such as when and how you eat—and choosing foods that support liver health can go a long way in maintaining optimal liver function over the long term.
Credit: Canva
World Liver Day 2026 is observed every year on April 19 to raise awareness of the importance of liver health, focusing on preventing diseases such as cirrhosis and fatty liver through healthy lifestyles.
The liver is a key organ that filters blood, breaks down food, stores energy, and keeps the human body in balance.
However, rising metabolic risk factors, including high blood sugar and obesity, are increasingly driving cases of metabolic dysfunction-associated steatotic liver disease (MASLD).
Nearly one-third of the global adult population today lives with MASLD, which can remain asymptomatic for years but turn into deadly scarring (fibrosis), cirrhosis (advanced fibrosis and loss of some of the liver function), or even liver cancer.
The European Association for the Study of the Liver (EASL) launched World Liver Day in 2010. The day was established on April 19 to commemorate the EASL's founding in 1966.
This year, 2026, the World Liver Day theme is “Solid Habits, Strong Liver”. It emphasizes building consistent lifestyle habits, such as balanced diet, regular exercise, avoiding alcohol, and routine check-ups, to strengthen liver health and prevent diseases.
From filtering toxins to aiding in digestion and metabolism, the liver silently performs over 500 crucial functions in the body. The organ is also blessed with the ability to regenerate itself.
Yet data shows that 2 million lives worldwide are lost each year to liver disease. About 1.5 billion people suffer from chronic liver disease.
MASLD, formerly known as non-alcoholic fatty liver disease (NAFLD), has emerged as the most common liver condition worldwide. These patients suffer from either obesity, diabetes, metabolic syndrome, hypertension, or cholesterol problems.
According to a recent study published in The Lancet Gastroenterology & Hepatology journal, MASLD affected 1.3 billion people around the globe in 2023.
The alarming study estimates the numbers to further spike by over 38 percent to reach 1.8 billion cases by 2050, causing substantial health and economic impacts worldwide.
MASLD remains one of the most prevalent and rapidly growing liver conditions worldwide, with its prevalence marking a 143 percent increase between 1990 and 2023.
Also read: Why Regular Scans Are Crucial for Liver Cancer Patients: Doctors Explain
People with obesity, diabetes, central or abdominal fat, dyslipidemia, hypertension, and insulin resistance are more likely to have MASLD. Obesity is the strongest risk factor, with the likelihood rising steeply from overweight to severe obesity.
Other signs to watch for include
Certain lifestyle choices can accelerate liver damage, such as:
Early screening and detection are key to prevent irreversible stages. Yet liver disease can be prevented with lifestyle changes such as:
Credit: Canva
A growing number of young professionals aged 18 to 30 are being diagnosed with Irritable Bowel Syndrome (IBS), a trend that is linked to the pressures and habits of modern life, said health experts today.
World Irritable Bowel Syndrome Day is held annually on April 19th to raise global awareness, reduce stigma, and support the roughly 700 million people worldwide suffering from the condition.
According to health experts, the combination of long hours in the office, irregular diets, high-stress levels, and lack of physical activity has paved the way for a lifestyle that is making young adults increasingly susceptible to developing symptoms related to their gut.
Speaking to HealthandMe, Dr. Nidhi Rawal, Consultant - Pediatric Gastroenterologist and Hepatologist, Rainbow Hospital, explained the major risk factors that are taking a visible toll on digestive health.
1. Chronic stress
Young professionals are faced with a fast-paced job environment full of obstacles and demands that they experience daily, along with performance pressure and increased digital overload; all of these factors can hurt the gut-brain axis.
When the gut-brain axis becomes disrupted, the motility and sensitivity of the digestive system can be affected, producing gut-related symptoms, such as abdominal discomfort, excessive gas, and changes in bowel movements.
2. Dietary habits
The increased reliance on processed foods, increased frequency of ordering takeout and fast food, excessive caffeine consumption, and irregular meal schedules can disrupt digestion and alter the balance of healthy vs unhealthy microbiota in the digestive tract.
3. Skipping meals
Skipping meals or eating a late dinner can also raise risk of IBS, and worsen symptoms.
4. Lack of physical activity
Being sedentary for long periods of time results in slowing the digestion process and therefore increases the risk of constipation and bloating.
5. Poor sleeping habits
Common among people in this age group, this also affect hormones and digestion negatively.
6. Better access to diagnostic tests
Better access to diagnostic tests and awareness are leading to an increase in diagnosis of the condition, that can also enable faster treatment and early recovery.
What Is IBS?
Irritable Bowel Syndrome (IBS) is a common but often overlooked gastrointestinal disorder, and less than 15 per cent get diagnosed.
Common symptoms include
IBS remains undiagnosed for many years as people tend to normalize these symptoms over time or attribute them to "something they ate" or everyday stresses.
One reason for this delay in being diagnosed is that the symptoms occur intermittently.
It is also important to note that the presentation of these symptoms is inconsistent and unpredictable; there may be episodes where the IBS can last many days, and then completely resolve, thus providing a false sense of relief.
Therefore, many individuals choose to delay consulting with a physician due to their belief that the symptoms they are experiencing are not serious.
Another contributing factor is that there is still a degree of reluctance or discomfort associated with discussing problems related to the gastrointestinal tract openly; this only further complicates under-reporting statistics.
IBS is a functional disorder. Therefore, routine diagnostic testing will not reveal any visible abnormalities.
Many patients may assume that the symptoms they are experiencing are not "real" or are not significant enough to warrant seeking medical attention, even though the discomfort they experience can be quite significant and affect their daily lives.
To treat IBS effectively, those suffering from it need to adopt some lifestyle changes, such as
Regular mealtimes,
A balanced diet,
Exercise,
Stress reduction.
© 2024 Bennett, Coleman & Company Limited