Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
Credit: Instagram/Lisa Ray
Actress Lisa Ray was diagnosed with Multiple Myeloma, an incurable but treatable blood cancer, in 2009. She successfully went into remission but experienced a cancer relapse shortly after her wedding in 2012.
During her journey to recovery, she became a prominent advocate for cancer awareness and research. However, it was during this period, at the age of 37, that she also suffered chemo-induced menopause — a topic she brushed aside, not wanting to bring it up out of shame and fear, reflecting the taboo society still associates with the natural end of a woman’s reproductive phase.
In an interaction with HealthandMe, the Oscar-nominated film Water (2005) actress opened up about her experience with chemo-induced menopause.
“I went into chemo-induced menopause at 37. I was given no support. I was completely lost. And even for a subsequent decade after that, I couldn’t find any answers. I didn’t know how to take care of myself. I didn’t know I had options,” she said.
The actress shared that she normalized many of her symptoms and avoided speaking openly about menopause despite being candid about cancer.
“I was so vocal about cancer. I’m actually somebody who prefers to be quite truthful about what I’m going through. I don’t really like to hide things. I’m not secretive by nature. And yet, I carried this burning secret inside me for so many years,” she said.
“When I was being lauded as someone who was breaking through the silence of cancer, I was carrying the silent secret inside me. I couldn’t understand why for many years. And I realized today, I was carrying shame.”
She noted that menopause continues to remain a deeply misunderstood and under-discussed subject, despite affecting all women.
Lisa said conversations around menopause were absent even within families.
“My mother never talked to me about menopause. Of course, we discussed my period when I got it, but menopause was simply like a black box,” she said.
The actress recalled that discussions around perimenopause and menopause only began when many of her close friends started experiencing symptoms themselves.
Calling the silence around menopause “astonishing” and “extremely unjust,” Lisa said women’s hormonal health continues to be severely underfunded and misunderstood globally.
“Menopause impacts all women. Yet it’s treated like a dark secret,” she told HealthandMe.
Lisa added that once she began researching the issue, she became increasingly frustrated by the lack of awareness and medical attention surrounding menopause and hormonal health.
Menopause Not Getting Enough Attention
The actress said that after moving to Dubai, she began openly discussing menopause on social media, despite initially worrying about public reaction.
“Sometimes in social settings, women would almost shut down or turn away and say, ‘Don’t talk about that.’ But when I put it on social media, maybe it permitted a lot of other women to also find a place to have a conversation or a community,” she said.
To bring about change where women can speak freely about the topic and seek treatment early, Lisa has co-founded NuHer, a science-backed health clinic and platform dedicated to midlife care for women. It is designed to support perimenopause and menopause through personalized medical treatments, clinical psychology, and nutritional guidance.
When asked why she chose to focus on menopause and women’s hormonal health, the Four More Shots Please! actress stated, “Menopause is simply not getting the attention that it needs. Women are struggling to get the care that they need and understand their options.”
Lisa explained that while awareness around cancer has steadily improved in India since her multiple myeloma diagnosis in 2009, menopause remains “the next taboo or frontier.”
According to Lisa, NuHer aims to create a safe, science-backed space where women can access support without judgment or dismissal.
“We need a place where women can be heard, where they’re not dismissed, where they’re not gaslit, where they receive all the right science and the options they can choose for this journey,” she told HealthandMe.
She also criticized the tendency to dismiss menopausal symptoms as a “normal” part of aging without offering support or treatment options.
“Women are not broken. Menopause is not a disease like cancer that has to be cured. But women need support. We don’t need to normalize suffering,” Lisa said.
Speaking about aging and post-menopause life, Lisa argued that society often dismisses older women despite what she described as a biologically important phase of life.
“We’ve had terrible PR as aging women. We are dismissed and considered irrelevant when actually we’re stepping into our power age if we know how to take care of ourselves,” the acclaimed actress told HealthandMe.
However, the problem arises when menopause is left unaddressed, and the hormonal changes cause long-term health impacts, including bone health, heart disease risk, and possibly dementia.
“The problem is with the drop in hormones. If you don’t have strategies and lifestyle changes to support yourself post-menopause, you become a frail woman. Your bones suffer. You’re more prone to heart disease and possibly even dementia,” she said, urging more women to seek medical help during menopause and not suffer in silence.
Credit: AI generated image
GLP-1 agonist drugs like Ozempic, Mounjaro, and Wegovy, may not only help treat obesity and diabetes but also improve survival among breast cancer patients, according to a new study.
The research published in JAMA Network Open suggests that the GLP-1 agonist drugs can lower deaths in breast cancer patients as well as cut down the risk of recurrence of the deadly cancer.
Breast cancer patients who used GLP-1 RA had an overall lower risk of death from any cause over a 10-year follow-up period.
Similarly, breast cancer survivors who used GLP1-RAs for diabetes or obesity had a significantly lower risk of their cancer returning over 10 years following their initial treatment.
"This study suggests that GLP-1 drugs may offer protective benefits, potentially improving survival and recurrence risk in some female patients with breast cancer—whether this is related to weight control, improved cardiovascular health, or other mechanisms remains to be studied," said study senior author Bernard F. Fuemmeler, Chair in Cancer Research at Virginia Commonwealth University’s Massey Comprehensive Cancer Center.
The findings were based on a retrospective cohort study examining the electronic health records of more than 840,000 breast cancer patients who were diagnosed between 2006 and 2023 and also were obese or had type 2 diabetes.
Widely hailed as a medical breakthrough, the GLP-1s (glucagon-like peptide-1 receptor agonists) act like the gut hormones that regulate appetite and blood sugar.
It acts specifically on obesity and diabetes — well-established risk factors that significantly elevate the risk of breast cancer progression and recurrence.
GLP-1 medications help lower the risk of breast cancer by promoting weight loss and decreasing circulating tumor activity. It also lowers blood sugar.
Studies have showed that people taking GLP-1s also experience fewer chemo side effects. They were less likely to have anemia, blood clots in veins, low levels of white blood cells called neutrophils, low blood platelet count, sepsis, nausea and vomiting, fatigue, cardiomyopathy, and neuropathy after chemotherapy.
However, the Virginia Commonwealth University study researchers noted that further studies are needed to understand the biological mechanisms, if any, between GLP-1 RAs and breast cancer outcomes.
Read: High Blood Pressure? Daily Soy And Legume Intake May Help Lower The Risk: Study
Breast cancer is the most diagnosed cancer worldwide, accounting for over 2.3 million new cases annually.
According to the WHO's International Agency for Research on Cancer (IARC), it is the leading cause of cancer-related deaths among women, resulting in roughly 670,000 deaths globally each year.
It is also one of the most common cancers among women in the US, and accounts for nearly one-third of all female cancer cases.
The average risk of a woman in the US developing breast cancer sometime in her life is about 13 per cent.
Breast cancer patients who are also obese or have type 2 diabetes experience more aggressive cancer growth and worse outcomes. Prior studies have shown that weight loss treatment and surgery following a breast cancer diagnosis are associated with improved heart health and increased survival.
-Walk into any salon, and you'll be offered a facial for almost every skin concern under the sun. But somewhere along the way, targeted treatments like de-tanning started giving traditional facials a real run for their money. If your main concern is sun damage, uneven tone, or that stubborn dullness that builds up over weeks of stepping out, the de tan vs facial debate is worth having properly.
The perfect de-tan face mask used consistently at home can deliver results that genuinely rival a salon treatment. It helps you in targeting pigmentation and sun damage right at the source without the appointment, the wait, or the cost. What keeps those results going between sessions is just as important. A daily de-tan face wash helps prevent surface tan from quietly rebuilding.
So eventually your skin holds onto its progress rather than starting from scratch every week. Here's a proper breakdown of the difference between de-tan and facial so you can make the right call for your skin.
The core difference comes down to what each treatment is actually designed to do.
De Tan is a targeted treatment built around one primary goal. It aims to dissolve surface-level pigmentation and sun damage. It is made up of chemical exfoliants like AHAs, brightening ingredients like vitamin C or kojic acid, and clay formulas that peel away tanned, dead skin cells to expose younger skin underneath.
A facial is a multi-step ritual that addresses overall skin health, not just one specific condition. It usually comprises cleansing, exfoliating, steaming, extraction, massage, and masks. Each phase has a particular objective. A facial is a great way to boost circulation, tackle a range of skin issues all at once, and give your skin a really good refresh.
Including a targeted de-tan mask in the weekly regimen can help those who want to keep their skin more even-toned and brighter in between salon visits. Exfoliating acids, oil-balancing clays, and barrier-supporting elements fuel a product that targets dullness, uneven texture, and stubborn tan without stripping the skin.
Products like the Foxtale Skin Radiance De-Tan Mask are particularly helpful for oily, mixed, and sun-exposed skin types since they combine light exfoliation with skin-brightening treatment. Over time, a de-tan treatment at home may make skin seem brighter, fresher, and more radiant when used regularly in conjunction with daily sunscreen.
Oily & Acne-Prone Skin
For oily and acne-prone skin, a targeted de-tan treatment is almost always the safer choice over a traditional facial. Most salon facials designed for brightening use heavy cream-based products, facial massages with oils, and steam, all of which can aggravate acne, clog pores, and trigger fresh breakouts on skin that's already overproducing sebum.
When you use a detan mask with Kaolin Clay and AHAs, it controls excess oil and pigmentation. It does all this without introducing anything that worsens breakouts for you. If you have oily skin, at-home detan treatments done consistently outperform most salon facials in both safety and visible results.
Dry & Dehydrated Skin
A traditional facial that includes a hydrating massage and a nourishing mask can work well here because it addresses moisture levels alongside surface concerns.
That said, a detan treatment isn't off the table for dry skin. The key is picking the right formula, one that uses gentler AHAs like Lactic Acid rather than stronger Glycolic Acid, and that includes hydrating ingredients like Ceramides or Hyaluronic Acid to counterbalance the exfoliation.
Dull & Sun-Damaged Skin
When the skin is suffering from a noticeable tan, uneven tone, and stubborn dullness from sun exposure, a detan treatment is the gold standard of 2026. A facial can provide a glow to your overall tone, but it doesn’t target the melanin deposit that produces your tan and pigmentation. A detan mask with Glycolic Acid, Niacinamide, and brightening clays works on the actual source of the problem, and with consistent use, the results compound over time in a way that a monthly salon facial simply can't replicate.
Here's a simple way in which you can decide:
Choose a De-Tan when:
Choose a Facial when:
For most people, the best approach isn't choosing one over the other permanently. In fact, you should understand when each serves your skin best and use them accordingly. A weekly de-tan treatment at home, with an occasional facial when your skin needs a deeper reset, covers most bases without overcomplicating your routine.
The facial vs de-tan debate doesn't have a single winner. It actually depends entirely on what your skin is dealing with and what goal you are trying to achieve. If you have issues with tan, pigmentation, and sun damage, a dedicated detan treatment is a better option for you.
Overall skin health, hydration, and multi-concern maintenance are where a facial earns its place. Know what your skin needs, pick the right tool for the job, and stay consistent; that's where the real results come from.
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