Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

Credit: AI
Every year, as the monsoon rolls in, hospitals and clinics across India see a familiar pattern: a sharp uptick in children and elderly patients presenting with vomiting, diarrhoea, and dehydration.
Doctors attribute this seasonal surge to a combination of contaminated water supplies, deteriorating food hygiene, and warm, humid conditions that favour the spread of viruses like rotavirus and norovirus.
Heavy rains and flooding routinely compromise municipal water lines, allowing sewage to mix with drinking water. Street food and produce are more prone to contamination during this period, and the humidity itself accelerates bacterial and viral growth.
Acute gastroenteritis, an inflammation of the stomach and intestines, is consistently one of the fastest rising monsoon health conditions, with rotavirus being a leading cause in children and norovirus a common culprit across age groups.
Rotavirus is a highly contagious, wheel shaped virus and remains the leading cause of severe diarrhoeal illness and death in children under five worldwide. It spreads through the faecal oral route via contaminated water, food, surfaces, or close contact with an infected person, and can cause several days of intense vomiting and watery diarrhoea, putting young children at real risk of rapid dehydration.
The good news: Rotavirus vaccines, given orally in a series of doses before 8 months of age, are highly effective at preventing severe disease and are recommended as part of national immunisation programmes.
Boil or filter all drinking water during the monsoon months. Avoid ice and beverages of uncertain origin, especially from street vendors.
Steer clear of cut fruits, chaat, and other street food that has been sitting exposed. Cook food thoroughly and eat it hot. Avoid reheated leftovers stored without refrigeration.
Also read: Dengue & Guillain-Barré Syndrome: Can A Common Monsoon Illness Trigger A Serious Nerve Disorder?
Frequent handwashing with soap before eating, after using the toilet, and after changing diapers remains one of the single most effective, low cost interventions against faecal oral transmission.
Ensure infants complete their full rotavirus vaccine schedule on time. Vaccination substantially reduces hospitalisations and severe outcomes, even though it does not eliminate all seasonal transmission.
Because these viruses spread easily within households and childcare settings, keep infected individuals' utensils and linens separate, and disinfect surfaces regularly during an active infection.
Most cases of viral gastroenteritis are self limiting, but caregivers should watch for signs of dehydration that require urgent medical attention:
Also read: Beware! Common Mistakes New Parents Make During Their Baby’s First Monsoon
Oral Rehydration Solution (ORS) is the cornerstone of management.
A simple homemade version consists of 1 litre of boiled and cooled water, 6 teaspoons of sugar, and half a teaspoon of salt. It can be lifesaving when commercial ORS packets are not available, though pre mixed WHO formula ORS is preferable when accessible.
Zinc supplementation (around 20 mg daily for 10 to 14 days) is recommended for children under five, as it has been shown to reduce the duration and severity of diarrhoeal episodes.
Antibiotics are not effective against viral gastroenteritis and should only be used if a bacterial cause, such as cholera, is confirmed by a doctor. Inappropriate antibiotic use can do more harm than good.
Continue feeding. For breastfed infants, continue breastfeeding throughout the illness. For older children and adults, small, frequent sips of fluids and bland, easily digestible food are better tolerated than large meals.
Seek medical care promptly if there is persistent high fever, visible blood in the stool or vomit, signs of moderate to severe dehydration, or if symptoms do not improve within 2 to 3 days, particularly in infants, the elderly, or anyone with underlying health conditions.
By Dr. Geeta Malkan Billa, Director of Gastroenterology & Hepatology at Dr. L. H. Hiranandani Hospital
Credit: AI
Urinary tract infections are common. A lot of people get them every year. When you have a tract infection you might feel a burning sensation when you go to the bathroom you might have to go to the bathroom a lot and your lower belly might hurt. These symptoms can get in the way of your life. You might want to try to make the pain go away on your own. Taking medicine without prescription is not a good idea.
Taking antibiotics when you do not need them can be bad for you. Urinary tract infections can become harder to cure when the bacteria get used to the medicine. This is called resistance and it is a big problem for everyone’s health. When this happens, you might get tract infections repeatedly and you might have fewer choices, for treatment. That is why it is so important to go seek medical attention at the earliest.
Most Urinary Tract Infections are caused by bacteria that are usually in the digestive tract and then get into the urethra. Things like not having water, not keeping yourself clean having something wrong with the urinary system or having a weak immune system can make it more likely for bacteria to grow.
If you take the medicine or stop taking it too soon the strong bacteria will live and get stronger. Over time these bacteria will not be affected by the medicines, which makes them very hard to treat. This is what happens when you have a Urinary Tract Infection that is resistant to drugs. Urinary Tract Infections, like these are very tough to deal with.
Also read: Kidney Stones In Urban India: Causes, Prevention, And Modern Treatment
Recognizing the early warning signs helps prevent the infection from spreading deeper into the body. Common signs of a UTI include:
Also read: Prostate Cancer: NHS England's New Precision Radiotherapy Offers Hope In Just 5 Sessions
Preventing tract infections is always better than treating them especially now that we have a lot of antibiotic resistance. If you do simple things every day you can reduce the risk of bacteria getting into your urinary system.
Here are some things that can help:
1. Stay well hydrated: Drinking water is very important for urinary health. When you drink fluids during the day it helps wash away bacteria from the urinary system. This lowers the chance of getting an infection.
2. Prioritize good personal hygiene: Doing things to stay clean can help lower the chance of a UTI. It is best to wipe from front to back after going to the bathroom. This keeps bacteria from the stomach area from moving into the system.
3. Don’t delay urination: Going to the bathroom regularly helps stop bacteria from growing. If you hold your urine for long it can create a place where bacteria grow faster. This makes it more likely to get an infection.
4. Be cautious with intimate hygiene products: Products that have smells, like sprays or douches can hurt sensitive areas. They can also change the balance of bacteria that protect the body. This might make UTIs more likely.
5. Wear breathable fabrics: Choosing cotton underwear and clothes that're not tight helps keep the area dry. A dry and cool place is not a home, for bacteria. This lowers the chance of getting an infection.
Also read: Can You Flush Out A UTI By Drinking More Water?
Accurate diagnosis is essential before starting any medication. Diagnosis start with an evaluation and a simple urine test called a urinalysis to check for bacteria white blood cells and red blood cells.
In cases a urine culture is also done. This test finds the strain of bacteria causing the infection and tests it against different medications to find out which antibiotic will work best. For people who have recurring UTIs imaging tests, like ultrasound or CT scans might be used to look at the structure of the urinary tract and find any blockages or problems that are there.
Also read: Turns Out, Peeing In The Shower Could Have Unexpected Dangers
Urinary tract infections or Urinary Tract Infections can usually be treated with antibiotics. You must take all the antibiotics even if you start to feel better so that you can be sure the Urinary Tract Infection is gone and you do not get sick again.
Medicines also help with the pain and discomfort you feel when you urinate, such as burning or feeling like you must go to the bathroom all the time.
In some cases, Urinary Tract Infections may recur due to underlying conditions such as kidney stones, urinary tract blockages, an enlarged prostate or structural abnormalities of the system. When these factors are identified, treating the root cause becomes essential.
Procedures such as kidney stone removal, stent placement or corrective surgery for urinary tract abnormalities may be recommended to prevent repeated Urinary Tract Infections.
Prevention and early intervention remain the effective strategies, in managing Urinary Tract Infections. Being aware of the warning signs and getting care at the onset of symptoms and avoiding unnecessary antibiotic use can significantly reduce the risk of recurrent Urinary Tract Infections and serious complications.
With diagnosis and appropriate treatment most Urinary Tract Infections can be successfully managed, safeguarding both urinary health and overall well-being.
By Dr. Arif Akhtar, Principal Consultant - Urology, Robotics and Renal Transplant, Manipal Hospital, Gurugram
Credit: AI
By the time we enter our 40s, the lungs begin to undergo gradual changes that can affect breathing capacity and respiratory reserve. While some changes are a normal part of ageing, persistent cough, breathlessness or recurrent chest infections should not simply be dismissed as getting older.
Experts explain why lung health deserves greater attention after 40, which everyday habits can help protect the lungs, and when screening or medical evaluation may be needed.
As we age lung tissue elasticity declines and chest wall mechanics stiffen. From an oncology standpoint, age-related cellular damage and long-term exposure to cancer causing agents like tobacco increase cancer risk. Looking after lung health from young age builds the respiratory reserve needed to tolerate advanced medical or surgical interventions if required as you get older.
Engage in regular aerobic conditioning exercises to maintain full breathing capacity. Reduce carcinogen exposure by avoiding active and passive tobacco smoke, and ensuring proper ventilation while cooking. using HEPA air purifiers may help to an extent. Maintain an antioxidant-rich diet to combat cellular oxidative stress.
2 to 3 week cut off is applicable here. A persistent cough lasting over three weeks, progressive exertional breathlessness, recurrent chest infections, coughing up blood, or unexplained weight loss are red flags. This is for both smokers and nonsmokers. Early-stage lung cancers are frequently asymptomatic or subtle; ignoring these signs delays diagnosis. These symptoms are that of TB as well. So, that should be ruled out.
Annual flu and once in lifetime pneumococcal vaccine prevents severe pulmonary infections. For high-risk individuals—such as heavy past or present smokers—a annual Low-Dose CT (LDCT) scan is the gold standard for early lung cancer detection, finding lesions when they are most curable. Eliminating tobacco, mitigating indoor air pollution, exercising, and maintaining balanced nutrition significantly lower cancer risk and improve overall survival outcomes.
By Dr. Sandeep Nayak, Chairman of Oncology, MACS-Renova Oncology Institute, KIMS Hospital, Bangaluru
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