Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

A cough that lingers for weeks is often dismissed as a stubborn cold, allergy, or lung infection. However, ENT specialists warned that in some cases, the real cause may be acid reflux, a condition that can affect the throat even without the typical symptom of heartburn.

Doctors told HealthandMe that recognizing the signs early can help patients receive the right treatment and prevent long-term complications.

When Does Acid Reflux Trigger a Chronic Cough?

According to Dr. Nishit Shah, ENT/Otorhinolaryngologist at Bombay Hospital, acid reflux, also known as gastroesophageal reflux disease (GERD), does not always present with chest burning.

"Sometimes people with reflux do not feel the usual symptom of heartburn in their chest. Instead, the acid from their stomach goes up into their throat, irritates it, which can cause a dry cough that will not go away, a hoarse voice, or a feeling that something is stuck in their throat," Dr. Shah told HealthandMe.

He advised that if a cough lasts for more than eight weeks and does not improve with usual medicines, acid reflux should be considered as a possible cause.

"It is very important to know what is causing your cough because if you just treat the cough, the acid reflux can still be hurting your throat," Dr. Shah said.

Not Every Throat Symptom Is Acidity

Also read: 'Let's Fix Our Food': India Launches New Policy To Fight Childhood Obesity, Boost Nutrition

However, not every throat symptom should be dismissed as acidity.

Dr. Alok Aggarwal, Chairperson, ENT, Sir Ganga Ram Hospital, said silent reflux often presents as intermittent throat irritation, a sensation of something stuck in the throat, or occasional voice changes.

"These symptoms are often judged as acidity by the common man, and people start self-medicating with antacids and even ayurvedic medicines. Less do they know that this can be a symptom of some underlying ENT disease," he said.

He explained that laryngopharyngeal reflux disease (LPRD) occurs when food or semi-digested food enters the pharynx, irritating its lining.

"It causes symptoms such as throat irritation, burning sensation, pain in throat, nasal irritation, globus sensation and change in voice," Dr. Aggarwal told HealthandMe.

ENT Evaluation Is Essential

Read More: Japanese PM Sanae Takaichi Sleeps 3 Hours A Night: How Much Sleep Do You Really Need?

While LPRD is commonly diagnosed, Dr. Aggarwal cautioned that similar symptoms may also be caused by allergic rhino-pharyngitis, chronic rhino-sinusitis, vocal nodules or polyps, laryngeal leukoplakia, and candida infection.

"Though this comes as the most common diagnosis in clinical practice, it often overshadows some very serious conditions which mimic the symptoms, and only after a thorough ENT examination can the exact diagnosis be made," he said.

He added that these conditions can be effectively diagnosed through thorough history-taking, clinical examination, and endoscopic examination.

"As doctors, we need to educate our patients regarding the disease physiology and the differentials it carries before establishing any diagnosis. A timely and adequate intervention with planned treatment can effectively cure the patient in most cases," Dr. Aggarwal said.

Lifestyle Changes May Help Control Symptoms

Dr. Shah recommended avoiding heavy meals, especially at night, limiting fatty foods, maintaining a healthy weight, and sleeping with the head elevated to help manage acid reflux.

"If people know that acid reflux can cause a cough, they can get a diagnosis sooner, get the right treatment and finally feel better," he added.

Dr. Aggarwal stressed the importance of timely medical evaluation.

"Early diagnosis and treatment can avoid unnecessary medications and avoid missing out on serious complications. A stitch in time saves nine," he said.

Japanese Prime Minister Sanae Takaichi has sparked debate after revealing that she gets very little sleep since taking office.

In a post on X, Takaichi wrote that she had managed to get "five full hours of sleep for the first time in ages"—an improvement from her usual "zero to three hours" a night since becoming prime minister.'

"On weekdays, by the time I get back to the residence, I'm maxed out on private time just handling bath cleaning, bathing, dinner, washing up afterward, laundry, and some light tidying," she wrote.

"So the late-night hours after that get consumed until dawn with reading materials brought back from the Prime Minister's Office or prepping for … question time."

Takaichi added that whatever free time remained was spent ironing handkerchiefs, catching up on laundry, and repairing clothes.

While the disclosure offered a rare glimpse into the pressures of Japan's highest office, it also sparked a nationwide debate about the health risks of chronic sleep deprivation.

"I think she should rest more," Democratic Party for the People leader Yuichiro Tamaki said at a news conference.

"Why doesn't her entourage provide more support to create an environment in which she can make important decisions with a fresh mind?"

However, some of Takaichi's colleagues defended her.

"Each person has their own various circumstances and behind-the-scenes stories, and on the premise of fulfilling responsibilities in public duties, I would be grateful if you could understand," Deputy Foreign Affairs Minister Ayano Kunimitsu wrote on X.

Also read: Could Poor Sleep Be One of the Earliest Signs of Alzheimer's Disease? Study Says Yes

How Much Sleep Do You Really Need?

Dr. Nitin Dange, Comprehensive Stroke and Endovascular Neurosurgeon at Lilavati Hospital and Research Centre, Mumbai, told HealthandMe that regularly missing sleep can increase the risk of neurological problems over time.

"Currently, due to hectic schedules, people are now sacrificing sleep to meet work deadlines, study longer, or spend more time on screens. Missing a few hours of sleep once in 2-3 months is harmless.

However, chronic sleep deprivation can not only cause irritation and weight gain but also neurological issues. During sleep, the brain processes memories, repairs nerve cells, regulates emotions, and clears waste products that accumulate throughout the day," Dr. Dange said.

A recent research, published in the journal Alzheimer's & Dementia, suggests that disruptions in rapid eye movement (REM) sleep, during which we dream, consolidate memory, and process emotions, could be among the earliest biological signs of Alzheimer's disease.

Dr. Priyam Bordoloi, an Internal Medicine Resident from Assam, also highlighted the dangers of sleeping less than six hours a night.

"When you hit deep sleep, your brain's glymphatic system activates. Think of it as a plumbing system that actively flushes out metabolic waste and neurotoxic proteins (like beta-amyloid) accumulated during the day. When you consistently sleep less than 6 hours, you cut this vital cleaning cycle short. The toxins build up. If you do not fix this, you are actively fast-tracking your risk for Alzheimer's, Parkinson's, stroke etc. It's a bad habit we all need to fix," he wrote on X.

Tips To Sleep Better

Experts recommend getting 7-9 hours of sleep every night for optimal brain health.

• Maintain a consistent sleep and wake-up schedule.
• Avoid screens, caffeine, and heavy meals before bedtime.
• Exercise regularly, but avoid intense workouts late at night.
• Keep your bedroom quiet, cool, and dark.
• Consult a doctor if you snore loudly, stop breathing during sleep, or feel excessively sleepy during the day.

The ovaries are a pair of pelvic organs in biological females associated with reproduction. Cancer of the ovaries is unfortunately increasing in incidence and usually presents late in the course of the disease. Ovarian cancer is often called the ‘silent killer’ because of the symptoms, which can be vague and easily mistaken for minor digestive issues. To date, we do not have a reliable tool to screen and detect ovarian cancer early.

Certain risk factors for ovarian cancer increase your chance of getting it in the future. An important point to keep in mind is that having a risk factor alone does not mean one will develop ovarian cancer in the future.

Conversely, some people who get ovarian cancer may not have any known risk factors. Some risk factors, like smoking, can be changed.

Others, like genetic mutations or family history, can’t be changed. Scientists have discovered several risk factors that increase a person’s chance of developing epithelial ovarian cancer.

These include:

Older age: Most ovarian cancers begin after menopause. If one experiences pelvic bleeding after menopause, it is important to see a doctor.

Genetics: Ovarian cancer does run in families. The most common inherited gene mutations are BRCA1 and BRCA2. We now have very reliable tests to detect these genetic mutations and tailor-made specific treatments which are effective.

Hormones: Hormones play a complex role in the development of ovarian cancer. In general, the total number of times a woman ovulates during her lifetime is related to her risk of ovarian cancer. More ovulations can mean a higher risk. Thus, early menses (before 12 years of age) or late menopause (after 52 years of age), and use of hormone replacement after menopause do increase your risk. Pregnancy and breastfeeding are considered protective.

Lifestyle: Certain factors such as lifestyle choices are within our control. While we cannot change our DNA or our reproductive history, certain lifestyle choices like smoking, drinking, and lack of exercise may influence our biological environment.

Weight Management: Research suggests a link between obesity and an increased risk of several cancers, including ovarian cancer. Adipose (fat) tissue produces estrogens, which can fuel certain cellular changes. Maintain a healthy weight to reduce your risk.

Sedentary Habits: Many studies suggest that regular exercise such as walking, yoga, and weight training can reduce your risk of ovarian cancer.

Smoking: While primarily linked to lung cancer, smoking is strongly associated with mucinous ovarian cancer, a specific subtype of the disease.

Dietary Patterns: While there is no singular “superfood” that can help prevent cancer, consuming a diet rich in vegetables, lots of lean proteins like fish, chicken, eggs, tofu, etc, and whole grains can help support a healthy immune system.

Every year, World Ovarian Cancer Day is observed on May 8. This is an initiative to raise awareness globally for educating the public about symptoms, risk factors, and the need for early detection of ovarian cancer. This year’s theme was No Woman Left Behind, which aims to ensure that all women have access to means of early detection, quality care, support, and to spread awareness so that no symptoms are ignored.

We should all do our bit but not spread fear or stigma. Since there is no universal screening tool for ovarian cancer, awareness of symptoms and associated risk factors is key. By recognizing the interplay between our genes, our hormonal history, and our daily habits, we can hope to move toward a future where ovarian cancer is detected earlier and treated more effectively.