Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

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Thyroid Disorders Affect Men Too: How They Impact Sperm Health

Updated May 25, 2026 | 07:00 PM IST

SummaryAccording to doctors, thyroid hormones play an important role in sperm production, sperm maturation, libido, and sexual performance. Timely diagnosis and treatment can significantly improve reproductive health.
Thyroid Disorders Affect Men Too: How They Impact Sperm Health

Credit: iStock

Thyroid disorders don’t just affect women — it also affects men and raise fertility risks, said experts today on World Thyroid Day.

While thyroid disorders are commonly linked to symptoms such as weight gain, fatigue, mood swings, and hair loss, experts highlighted a lesser-known impact of thyroid imbalance — its effect on male fertility and reproductive health.

Dr. Piyush Lodha, Endocrinologist at Ruby Hall Clinic, Pune, told HealthandMe that both hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) can negatively affect sperm health and reproductive function in men.

“The thyroid regulates several important body functions, including metabolism and hormone balance. Even slight thyroid dysfunction can influence fertility because thyroid hormones are closely connected to reproductive hormones,” he explained.

How Thyroid Imbalance Affects Male Fertility

The doctors noted that thyroid hormones play an important role in sperm production, sperm maturation, libido, and sexual performance.

In hypothyroidism, reproductive processes may slow down significantly. Men may experience low testosterone levels, reduced libido, erectile dysfunction, and poor sperm quality.

Dr. Lodha noted that hypothyroidism can negatively affect sperm count, sperm motility, and sperm morphology, lowering the chances of successful conception. Fatigue, depression, and weight gain associated with thyroid disorders may further impact sexual health and self-esteem.

Hyperthyroidism can also affect fertility. Excess thyroid hormone may disturb the hormonal balance required for normal sperm production.

“In men, hyperthyroidism can lead to premature ejaculation, increased oxidative stress, and damage to sperm cells. In some cases, sperm concentration and semen volume may also decrease,” he said.

The expert warned that thyroid-related fertility issues often remain undiagnosed because symptoms develop gradually or are mistaken for stress and lifestyle-related problems.

Early Diagnosis Can Improve Outcomes

The expert stressed that timely diagnosis and treatment can significantly improve reproductive health.

“With hormonal therapy, dietary modifications, and regular monitoring, sperm health and reproductive function can improve over time,” Dr. Lodha explained.

He advised men experiencing unexplained infertility, sexual dysfunction, or persistent fatigue to undergo comprehensive reproductive health evaluations, including thyroid function tests.

Lifestyle Reasons Behind Surging Thyroid Disorders

Dr. Anu Mathew, Consultant Endocrinology, Fortis Hospital, Manesar, told HealthandMe that while women are more at risk, thyroid disorders can also affect men and children, and a lack of awareness often delays diagnosis.

She added that thyroid disorders are increasingly being linked to lifestyle-related factors, despite autoimmune disease remaining the most common cause.

Also read: Heatwaves And Toxic Air Create A Growing Health Crisis In Delhi

Dr. Anu pointed out that subclinical hypothyroidism (SCH) — characterized by elevated thyroid-stimulating hormone (TSH) with normal T3 and T4 levels — has shown strong associations with lifestyle factors in several studies.

“Both iodine deficiency and iodine excess have been associated with thyroid disorders. Lack of sleep, poor sleep quality, chronic stress, smoking, and sedentary lifestyles may also contribute to thyroid dysfunction,” she said.

According to experts, subclinical hypothyroidism has also been associated with increased risks of cardiovascular disease, insulin resistance, and metabolic syndrome.

The doctors, thus, stressed the importance of healthy lifestyle changes to prevent thyroid dysfunction and related complications.

When Thyroid Disorders Become Cancerous

Read More: Ebola Cases Cross 900, Death Toll Tops 200; 10 Countries On High Alert

Dr. Manjunath NML, Senior Consultant – Surgical Oncology and Robotic & Laparoscopic Surgeon at HCG Cancer Hospital, Bengaluru, told HealthandMe thyroid cancer is often difficult to detect early because it grows slowly and may initially cause painless or nonspecific symptoms.

“Small thyroid nodules may go unnoticed because they are not always visible or palpable during routine examinations,” he explained.

Detection may become even more challenging in obese patients, where larger nodules can remain hidden.

Doctors also highlighted that cancerous nodules may sometimes be concealed within multinodular goitre, a condition commonly associated with iodine deficiency and more frequently seen among women in endemic regions.

Other reasons for delayed diagnosis include lack of awareness, socioeconomic barriers, and limited access to specialists and diagnostic technologies such as ultrasound and FNAC (fine needle aspiration cytology).

Experts noted that imaging tools like the TIRADS (Thyroid Imaging Reporting and Data System) scoring system play an important role in classifying thyroid nodules as benign, suspicious, or malignant, helping guide appropriate treatment decisions.

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Weight Gain Isn’t Always Lifestyle: Understanding the Thyroid-Metabolism Connection

Updated May 25, 2026 | 09:00 PM IST

SummaryNot every person who gains weight has a thyroid problem, and not every thyroid patient experiences noticeable weight changes. Weight is influenced by many factors, including sleep, stress, age, and overall health.
Weight Gain Isn’t Always Lifestyle: Understanding the Thyroid-Metabolism Connection

Credit: iStock

When people gain weight, the first thought often revolves around poor eating habits or a lack of physical activity in their daily routine. While that may be true, the cause of weight gain may be more than what meets the eye. One could have gained weight gradually despite the lack of significant changes in his/her lifestyle. In such cases, an underlying health condition such as a thyroid disorder could be contributing.

What Does The Thyroid Actually Do?

The thyroid is a small gland found in the neck region. But it plays a huge part in the body’s activities. This gland secretes hormones that control metabolism, i.e., the body’s capability to convert food into energy. The hormones released by the thyroid control many other body functions, including heart rate, body temperature, etc.

When the thyroid gland becomes underactive, a condition called hypothyroidism occurs, and it causes bodily functions to slow down. In turn, metabolism may be reduced, causing some alterations in people's well-being.

Weight Gain Is Often Not The Only Symptom

People suffering from hypothyroidism may experience other common symptoms besides weight gain, such as fatigue, lack of energy, constipation, dry skin, hair loss, mood swings, and intolerance to cold temperatures. However, thyroid-related weight gain is often misunderstood. It is usually gradual and may not always be dramatic. In many cases, the change can happen because of slowed metabolism and fluid retention.

Knowing When To Pay Attention

Not every person who gains weight has a thyroid problem, and not every thyroid patient experiences noticeable weight changes. Weight is influenced by many factors, including sleep, stress, age, and overall health.

However, if weight gain feels unexplained and is accompanied by other persistent symptoms, it may be worth seeking medical advice. Simple tests can help assess thyroid function and identify problems early. Sometimes, understanding the reason behind weight changes can be the first step toward better health.

Understanding Treatment And Management

The good thing here is that thyroid-related conditions are easily manageable after proper diagnosis. Treatment for hypothyroidism entails administering medications that help normalize hormonal levels in the body. Such therapy helps in balancing metabolic processes naturally.

Along with medical treatment, lifestyle measures remain important. Maintaining a balanced diet, regular physical activity, adequate sleep, and stress management can support overall metabolic health and help improve quality of life. However, people should avoid self-medicating with supplements or relying on unverified remedies claiming to “boost” thyroid function.

As awareness around metabolic health grows, World Thyroid Day is an opportunity to move beyond assumptions. Understanding the connection between thyroid function and metabolism can help people recognize symptoms early and seek timely care. Sometimes, the body may be signaling that there is more to the story than lifestyle alone.

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Why Ebola Does Not Spread Like COVID-19: Experts Explain

Updated May 25, 2026 | 06:00 PM IST

SummaryThe experts explained that Ebola is far more difficult to spread than airborne respiratory viruses such as influenza, COVID-19, measles, and even the Andes strain of hantavirus, which recently caused an outbreak on a cruise ship.
Why Ebola Does Not Spread Like COVID-19: Experts Explain

Credit: AI generated image

The ongoing Ebola outbreak in Africa, with nearly 1,000 cases and over 200 deaths, has sparked concerns among people, bringing back memories of the COVID-19 pandemic. With every new outbreak, fears about viruses becoming airborne like SARS-CoV-2, the virus behind COVID-19, tend to rise.

However, experts have clarified that Ebola is not airborne and does not spread like COVID-19.

Why Ebola Spread Is Not Like COVID

“Ebola is a serious viral hemorrhagic disease,” said Dr. Ishwar Gilada, Secretary General, People’s Health Organisation (India).

“Ebola does NOT spread through casual airborne exposure like influenza or COVID-19. Individuals become infectious only after symptoms begin, not during the incubation period. The incubation period ranges from 2 to 21 days,” he added.

Former AIIMS Director Dr. Randeep Guleria told PTI that Ebola is “a zoonotic infection, mainly originating in bats.”

“Ebola does not spread through air like respiratory viruses. It spreads only through direct contact with infected body fluids,” he added.

Experts further explained that Ebola is far more difficult to spread than airborne respiratory viruses such as influenza, COVID-19, measles, and even the Andes strain of hantavirus, which recently caused an outbreak on a cruise ship.

“Ebola is not airborne. There's no evidence of that at all. To be infected, you've got to have body fluid contact with someone who is quite ill,” said Michael T. Osterholm, Director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota.

According to Peter Hotez, Dean of the National School of Tropical Medicine at Baylor College of Medicine, people with Ebola do not spread the virus before developing symptoms.

The experts reiterated that during Ebola’s incubation period, which ranges from 2–21 days, an infected person is generally not contagious, unlike COVID-19, where transmission can occur before symptoms appear.

Moreover, even early Ebola symptoms such as fever, sore throat, headache, and body aches are less likely to spread the virus compared to respiratory infections.

Ebola does not spread through coughing, sneezing, or casual contact like shaking hands.

“You cannot get Ebola from passing someone in an airport, sitting near someone freely, or through other casual contacts,” explained Captain Satish K. Pillai, Incident Manager for Ebola Response at the US Centers for Disease Control and Prevention (CDC).

Also read: Ebola Cases Cross 900, Death Toll Tops 200; 10 Countries On High Alert

How Ebola Spreads

Ebola spreads through:

  • Direct contact with infected blood or bodily fluids
  • Contact with contaminated surfaces or medical equipment
  • Unsafe caregiving exposure
  • Traditional burial practices involving direct contact
  • Certain zoonotic animal exposures

Why Ebola Does Not Spread Like COVID-19: Experts Explain

Common Symptoms Of Ebola

Common symptoms include:

  • Sudden fever
  • Severe weakness and fatigue
  • Headache
  • Muscle and body pain
  • Sore throat
  • Abdominal pain
  • Vomiting and diarrhoea
  • Rash

Severe illness may involve:

  • Bleeding manifestations
  • Shock
  • Multi-organ dysfunction

Historical case fatality rates have ranged from 25% to 90%, depending on the virus strain, outbreak conditions, and access to timely medical care.

Ebola: How You Can Stay Safe

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  • Washing your hands often
  • Avoiding contact with bodily fluids
  • Avoiding contact with individuals who appear ill or who have a fever
  • Avoiding objects that have come in contact with an infected individual, such as bedding, clothing or medical equipment
  • Not handling someone who has died from Ebola
  • Avoiding contact with bats and nonhuman primates, and raw meat from these animals
  • Avoiding seeking medical care at hospitals where patients are being treated for Ebola
  • Paying attention to your health for 21 days after returning from a country where Ebola has been found
  • Seeking medical attention immediately if you experience any Ebola symptoms

How To Prepare Healthcare Systems

Dr Gilada stressed the importance of:

  • Immediate isolation protocols for suspected cases
  • PPE readiness across designated hospitals
  • Emergency infection control drills and refresher training for healthcare workers
  • Laboratory diagnostic preparedness with safe specimen handling
  • Contact tracing systems
  • Central and state public health coordination

The expert also urged authorities to strengthen “science, surveillance, preparedness, and infection control” to curb the spread of the disease.

Dr Guleria called for stricter infection control, timely isolation, and avoiding direct contact with infected persons remain key preventive measures. They also noted that Ebola outbreaks have largely remained confined to Africa due to effective containment efforts.

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