Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

Furosemide is commonly prescribed in the UK to help manage conditions such as heart failure and high blood pressure. The diuretic medication is used by people of all ages, including children and infants. In 2024 alone, it was dispensed around 11 million times, making it one of the 20 most frequently prescribed medicines in the country.

Although it is widely used, doctors stress that furosemide must be taken carefully and in line with medical advice, as misuse can lead to serious health problems.

Furosemide: Why The NHS Is Warning Furosemide Users About Dehydration

To ensure safe use, the NHS has issued guidance urging certain people to speak to a doctor before taking furosemide. This is particularly important for anyone showing signs of dehydration, which can include feeling unusually thirsty, having a dry mouth, or noticing dark-coloured urine. Because furosemide increases urine output, it can raise the risk of fluid loss if not managed properly.

Who Should Speak To A Doctor Before Taking Furosemide?

The NHS advises the following people to consult a doctor before using furosemide:

• Anyone who has previously had an allergic reaction to furosemide or any other medicine
• Anyone with low blood pressure, also known as hypotension
• Anyone showing signs of dehydration, such as thirst, dry mouth, or dark urine
• Anyone diagnosed with liver disease
• Anyone living with diabetes
• Anyone who has difficulty passing urine
• Anyone diagnosed with Addison’s disease, a rare disorder affecting the adrenal glands
• Anyone diagnosed with gout

Furosemide: When Should Users Contact A Doctor Or Delay Treatment

Beyond these groups, the NHS also says furosemide users should seek medical advice if:

• You are due to have a glucose test
• You are scheduled for a scan or X-ray that involves an iodine-based dye being injected into your blood
• You are preparing for major surgery or a procedure that requires a general anaesthetic

How Furosemide Works And Why It Is Called A ‘Water Tablet’

Official NHS guidance explains that diuretics are often referred to as “water tablets” because they increase how often you urinate. This helps the body remove excess fluid.

“Furosemide is only available on prescription,” the NHS states. “It comes as tablets and a liquid that you swallow. It can also be given by injection, but this is usually only done in hospital.”

Medicines That Can Interfere With Furosemide

The NHS also warns that certain medicines can reduce how well furosemide works or increase the risk of side effects. This includes some commonly used over-the-counter treatments, such as paracetamol, co-codamol, and remedies for heartburn or indigestion.

Common Painkillers And Remedies To Use With Caution

Anyone prescribed furosemide is advised to speak to a doctor before taking:

• Medicines used to treat mental health conditions, including amisulpride, lithium, pimozide, or risperidone
• Medicines used to treat high blood pressure, or drugs that may cause low blood pressure as a side effect
• Sucralfate, a medicine used to treat stomach ulcers. Patients should leave around two hours between taking sucralfate and furosemide
• Non-steroidal anti-inflammatory drugs, known as NSAIDs, such as diclofenac, ibuprofen, or naproxen

Why Potassium Supplements Can Affect Furosemide?

Other medicines can also interfere with how furosemide works, including:

• Potassium supplements, steroids, or other diuretics that affect potassium levels
• Medicines used to treat, or that may cause, irregular heart rhythms, such as amiodarone, digoxin, disopyramide, flecainide, or sotalol
• Soluble paracetamol
• Soluble co-codamol

Certain Treatments For Heartburn And Indigestion

The NHS advises patients to tell their doctor if they are taking potassium supplements, as these can alter potassium levels in the blood and affect how furosemide works.

The health service also cautions against combining furosemide with herbal remedies or supplements. According to NHS guidance, there is not enough evidence to confirm they are safe to take alongside the drug.

Unlike prescription and pharmacy medicines, herbal products are not tested to the same standards and are generally not assessed for how they interact with other medications.

High blood pressure, also known as hypertension, is usually thought of as an adult health issue. But doctors are now raising serious concerns after a study published in The Lancet Child & Adolescent Health in November 2025 showed that rates of high blood pressure among children and teenagers have nearly doubled over the past two decades.

Blood Pressure In UK: The Lancet Study and Why Doctors Are Concerned in the UK

Hypertension has long been associated with people in their 30s and 40s, often linked to work stress and ageing. Today, however, shifts in daily habits and increasingly inactive lifestyles mean the condition is appearing more often in children and adolescents too. For years, young people were largely overlooked in discussions around blood pressure, and routine screening was rarely carried out. As a result, the true scale of the problem remained unclear. UK doctors are now calling for a nationwide testing programme to assess how widespread the issue is and to identify children who may need early support and treatment.

What Is Hypertension?

Hypertension is the clinical term for high blood pressure. It develops when the force of blood pushing through the arteries remains higher than what is considered healthy over time. Arteries are the blood vessels that carry oxygen-rich blood from the heart to the brain and the rest of the body. High blood pressure is often described as a silent killer because it can cause lasting damage without clear warning signs or symptoms.

Blood Pressure: How Is It Diagnosed?

Blood pressure is usually checked using a monitor with an inflatable cuff placed around the upper arm. The reading is shown as two numbers, measured in millimetres of mercury, written as one over the other. The top number, known as systolic pressure, reflects the force of blood when the heart beats and pumps blood around the body. The bottom number, called diastolic pressure, measures the pressure in the arteries when the heart relaxes between beats.

The definition of high blood pressure varies between countries. In the UK, a normal adult reading falls between 90/60 and 119/79. Readings from 120/80 to 139/89 are considered raised, while 140/90 and above is classed as high blood pressure. In the United States, readings between 130/80 and 139/89 are labelled stage 1 hypertension, with stage 2 beginning at 140/90.

Diagnosing hypertension in children is more complex. Blood pressure naturally changes as children grow and depends on age, height, and sex. Rather than fixed numbers, doctors diagnose high blood pressure when a child’s readings fall within the highest five per cent for others of the same age, height, and sex.

Blood Pressure In UK: Who Is At Risk?

High blood pressure is widespread, particularly among older adults. Around one in three adults in the UK and nearly half of adults in the US live with hypertension. Age plays a key role because arteries gradually lose flexibility and become thicker over time. Family history also matters, as genetics can increase risk. People from Black African, Black Caribbean, and South Asian backgrounds are known to face a higher likelihood of developing the condition.

Lifestyle choices also have a strong influence. Diets high in salt, being overweight or obese, lack of regular physical activity, smoking, excessive alcohol intake, and prolonged stress can all contribute to raised blood pressure.

What About Children?

In babies and very young children, high blood pressure is usually linked to underlying medical issues such as heart defects, kidney disease, or genetic and hormonal conditions. This form is known as secondary hypertension. Since the 1990s, however, rates of high blood pressure among children and adolescents have risen more than fourfold, reaching around six per cent. Poor diets, low levels of physical activity, and increasing rates of overweight and obesity are major factors behind this rise.

Why Is Hypertension Harmful?

High blood pressure can quietly harm the body for many years before symptoms appear. Constant strain on the blood vessels can lead to aneurysms, where weakened artery walls bulge and may rupture, sometimes with fatal consequences. The heart is forced to work harder, increasing the risk of heart failure. Damage to the inner lining of arteries can trigger inflammation and the buildup of plaques, making blood vessels narrower and less flexible. This restricts blood flow and raises the risk of chest pain, irregular heartbeats, and heart attacks.

The kidneys are especially sensitive to high blood pressure. Damaged blood vessels can stop them from filtering waste effectively, potentially leading to kidney failure that requires dialysis or a transplant. The eyes can also be affected, as their delicate blood vessels are prone to damage, causing bleeding, blurred vision, or even blindness.

When blood flow to the brain is reduced by narrowed or blocked arteries, it can lead to vascular dementia or mini-strokes. Severe cases may result in major strokes caused by clots or bleeding linked to long-term high blood pressure.

In children, hypertension can harm vital organs such as the heart, kidneys, and eyes at an early age. This makes early detection and treatment crucial to protect long-term health.

Chickenpox will soon become part of the NHS routine childhood vaccination schedule, a step health leaders are calling a landmark moment for public health. Officials say the decision will strengthen population immunity, reduce hospital admissions, and help the NHS save substantial costs over time. It is also expected to cut down on missed nursery and school days for children, while easing the burden on parents who often have to take time off work to care for sick kids.

Doctors have also stressed that while chickenpox is often mild, it can lead to serious complications and, in very rare cases, can be life-threatening. Below, we answer key questions, including why the vaccine is being introduced now, which children are eligible for free NHS doses, and what parents should do if their child falls just outside the qualifying age group.

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Dr Claire Fuller, National Medical Director for NHS England, said the move marks a major step forward. “This is a hugely positive moment for children and their families,” she said, adding that routine protection against chickenpox will now sit alongside other childhood vaccinations designed to guard against serious illness.

Chicken pox vaccine: What Is Chickenpox?

Chickenpox is caused by the varicella zoster virus, which is why the letter “V” has now been added to the standard MMR vaccine. The illness mainly affects children, but anyone can catch it at any age.

During the pandemic, chickenpox cases fell sharply due to lockdowns and reduced social contact. As a result, experts believe natural immunity to the virus across the population remains lower than usual.

Although uncommon, complications can include serious bacterial infections such as group A streptococcus, brain swelling known as encephalitis, lung inflammation called pneumonitis, and even strokes. Very young babies under four weeks old face a higher risk of severe illness, as do adults who have never had chickenpox before.

Also Read: Australian Cricketer Damien Martyn in Hospital With Meningitis

Chicken pox vaccine: Why Is The NHS Rolling It Out Now?

Until now, chickenpox vaccination was not routinely offered to all children because of long-standing concerns about shingles. Shingles is caused by the same virus, which can lie dormant in the nervous system for years before reactivating later in life, often when immunity weakens due to age, illness, or stress.

In 2009, the Joint Committee on Vaccination and Immunisation decided against a nationwide rollout, fearing it could increase shingles cases among middle-aged adults. At the time, it was thought that natural exposure to chickenpox helped protect against shingles later on. More recent research from the United States, however, has challenged and largely dismissed that theory, paving the way for the NHS decision.

Chicken pox vaccine: Which Children Are Eligible And When?

Children born on or after 1 January 2025 will be offered two doses of the combined MMRV vaccine at 12 months and again at 18 months. Those born between 1 July 2024 and 31 December 2024 will receive two doses at 18 months and at 3 years and 4 months.

Children born between 1 September 2022 and 30 June 2024 will be offered a single dose at 3 years and 4 months. In addition, the NHS plans to introduce a one-dose catch-up programme later this year for older children born between 1 January 2020 and 31 August 2022.

Previously, children received two doses of the MMR vaccine at 12 months and at 3 years and 4 months. For children born on or after 1 July 2024, the second dose will now be brought forward to 18 months to offer earlier protection.

Chicken pox vaccine: What Happens Next?

The rollout across England, Scotland, Wales, and Northern Ireland means hundreds of thousands of children will become eligible for the vaccine from Friday. Parents should be contacted by their GP and invited to book appointments for the new combined MMRV jab as part of routine childhood vaccinations.

As per Mirror News, Dr Claire Fuller said the change ensures protection against measles, mumps, rubella, and chickenpox is now delivered together. She added that making the vaccine part of standard appointments will help keep children healthier and reduce the spread of these highly contagious infections.