Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

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Dismissed as Anxiety: Rebecca King-Crews Shares Decade-Long Struggle With Parkinson’s

Updated Apr 7, 2026 | 04:00 AM IST

SummaryThe US Food and Drug Administration (FDA) approved non-invasive surgical procedure, called bilateral focused ultrasound, uses sound waves directed into the brain to eradicate the debilitating symptoms of Parkinson's.
Dismissed as Anxiety: Rebecca King-Crews Shares Decade-Long Struggle With Parkinson’s

Credit: Chen Lab/Instagram

Rebecca King Crews, wife of actor Terry Crews, has opened up about her diagnosis with Parkinson's disease, which was previously dismissed as mere anxiety.

Speaking on the TODAY show, she also revealed a newly-approved procedure that has helped manage her symptoms. After three years, she’s able to write.

"I feel good," King Crews said during the segment. "I’m able to write my name and my dates, and I’m able to write with my right hand for the first time in probably three years."

Parkinson's Dismissed As Anxiety

The symptoms came suddenly and progressed quickly. Rebecca revealed that her first set of symptoms appeared around 2012, which began with numbness in her left foot while working out. It then progressed to a limp.

Then her left arm wasn't swinging as much as her right during certain exercises. Another was experiencing tremors while applying lip gloss, putting on makeup, or brushing her teeth. However, her doctor just thought she was having anxiety, the Today report said.

After three years of confusing symptoms, a Parkinson's specialist in 2015 recognized that she had the condition.

US FDA-approved treatment for Parkinson’s

Also read: Japan Approves First-Ever Stem Cell Therapies For Parkinson’s And Heart Failure

In the hope of a miracle, Rebecca was praying on her knees beside her bed when her husband, Terry Crews, informed her of a US Food and Drug Administration (FDA) non-invasive surgical procedure for her symptoms.

Last month, she underwent the new procedure called a bilateral focused ultrasound. The 2025 approved procedure uses sound waves directed into the brain to eradicate the debilitating symptoms.

What Is Parkinson's Disease?

Parkinson's disease is a progressive, neurodegenerative movement disorder caused by the loss of dopamine-producing brain cells, primarily affecting people over 60. Apart from motor loss, the disease also causes cognitive decline, depression, anxiety, and swallowing problems.

The first symptom may be a barely noticeable tremor in just one hand or sometimes a foot or the jaw. Over time, swinging your arms may become difficult, and your speech may become soft or slurred. The disorder also causes stiffness, slowing of movement, and trouble with balance that raises the risk of falls.

Also read: Is Parkinson's Disease Infectious?

What Is A Focused Ultrasound For Parkinson's?

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with symptoms secondary to Parkinson’s disease.

This novel technology focuses on beams of ultrasonic energy to targets deep in the brain without damaging surrounding normal tissue.

During the procedure, doctors use a device called Exablate Neuro, developed by a company called Insightec, to deliver ultrasound waves to specific areas on both sides of the brain.

They're guided by magnetic resonance imaging (MRI) to target the areas thought to be involved in the movement symptoms in Parkinson's.

The procedure typically produces immediate results and can be a good option for people who can't or don't want to pursue deep-brain stimulation, according to the Michael J. Fox Foundation for Parkinson's Research.

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Hip Fracture After 65: Why It Can Be Life-Threatening? Experts Explain How to Prevent

Updated Apr 6, 2026 | 08:00 PM IST

SummaryAccording to World Health organization (WHO), around 60 per cent of people living with osteoarthritis are women, yet awareness remains limited until symptoms begin to interfere with mobility and daily function.
Hip Fracture After 65: Why It Can Be Life-Threatening? Experts Explain How to Prevent

Credit: Canva

A fall at home might look small, but for women older than 65, a broken hip can be a big and serious health problem. In real medical terms, this condition has a 20 to 30 percent chance of being deadly within the first year.

As people get older, their bones get weaker because of osteoporosis, which makes them more likely to break even from small falls. However, the bigger problem starts once the injury happens.

According to World Health organization (WHO), around 60 per cent of people living with osteoarthritis are women, yet awareness remains limited until symptoms begin to interfere with mobility and daily function.

Loss Of Muscles

Reports show that 70 per cent of women will get arthritis and osteoporosis. Most of them had no idea it was coming. HealthandMe spoke to experts to understand the reasons behind the trend.

Dr Gurdeep Avinash Ratra, Consultant - Orthopedics and Joint Replacement, Manipal Hospitals, Gurugram said that the development of these disorders is gradual and closely tied to physiological changes.

“After the age of 30, there is a steady decline in muscle mass, accompanied by a more rapid reduction in strength and power. With menopause, the significant fall in estrogen levels removes natural protection for bone density and joint health. Over time, this leads to increased bone fragility, reduced muscular support, and stress on joints, thereby elevating the risk of fractures and chronic joint conditions,” Ratra told HealthandMe.

Health Coach Prashant Desai in a post on social media platform X, noted that after the age of 30:

  • muscle mass starts declining by 1 per cent every year.
  • muscle strength declines three times faster.
  • muscle power declines eight times faster.
“The moment you hit menopause, estrogen and progesterone drop to zero. Just like that. That is why arthritis and osteoporosis hit women so much harder than men. It is biology that most women are simply not prepared for,” Desai added.

Treatment

Experts said a hip fracture needs to be treated right away as a serious medical problem that requires care from many different medical specialists, not just a doctor who focuses on bones.

Dr Rajesh Kumar Verma, Director – Orthopedics & Joint Replacement, Max Super Speciality Hospital, Vaishali explained that limited movement can cause blood clots, chest infections, pressure sores, and loss of muscle quickly. Many patients also face a quick drop in their ability to take care of themselves, which can impact both their body and mind.

Also read: Suffering From Mid-back Pain? Doctors Say It May Be Spinal TB

“Delayed treatment further increases risk. Early surgery and prompt recovery treatment help increase the chances of surviving and recovering better,” Verma told HealthandMe.

Hip Fracture After 65: Why It Can Be Life-Threatening? Experts Explain How to Prevent

How to Prevent

  • Maintaining a healthy waist circumference as an early indicator of metabolic health.
  • Engaging in regular strength training to preserve bone density and muscle mass.
  • Ensuring adequate protein intake to support muscle maintenance.
  • Incorporating sufficient calcium and Vitamin D into the diet.
  • Remaining physically active, with exercise beyond low impact activities alone.
  • Get medical help right away if you fall or think you might have a broken bone.
  • Have surgery as soon as your doctor suggests it, because it can help you recover better.
  • Begin physiotherapy as soon as possible after the surgery to help restore movement and avoid any serious issues.
  • Make sure to eat well, paying special attention to getting enough protein, calcium, and vitamin D.
  • Check for fall risks at home by looking at things like lighting, floor surfaces, and handrails.
Also read: Strong Bones In Women: Expert Shares The Ideal Calcium-Vitamin D-Workout Blend

What to avoid

  • Do not wait to go to the hospital, even if the hip fracture pain feels okay.
  • Avoid staying in bed for long because a hip fracture can lead to infections, pressure sores, and blood clots.
  • Do not skip osteoporosis treatment for hip fractures because it is very important to stop broken bones from happening again.
  • Avoid skipping follow-ups or rehabilitation sessions for hip fractures after the surgery.

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Why Preventive Health Check-ups Are Important For Women

Updated Apr 6, 2026 | 04:01 PM IST

SummaryPeriodic health check-ups also provide an opportunity for counselling on nutrition, mental well-being, hormonal health, and lifestyle management, areas that are often overlooked but equally important.
Why Preventive Health Check-ups Are Important For Women

Credit: iStock

World Health Day serves as a reminder that regular preventive health check-ups stand as mandatory health assessments that all women need to undergo for their long-term health.

Many serious conditions, such as breast cancer, cervical cancer, thyroid disorders, diabetes, and cardiovascular diseases, often remain silent in their early stages, making regular screening the most effective way to detect them early, when treatment is simpler, less invasive, and more successful.

How Preventive Healthcare Can Help Women

Preventive healthcare enables women to take a proactive role in managing their health rather than responding to illness at an advanced stage. Early detection not only improves clinical outcomes but also effectively decreases treatment difficulties, emotional distress and financial costs while providing superior long-term life quality.

This also helps in identifying risk factors early, allowing timely lifestyle modifications that can prevent disease onset altogether.

Despite this, women often deprioritize their own health due to the multiple roles they juggle, balancing careers, caregiving responsibilities, and family needs. There is also a continued hesitation around discussing reproductive and intimate health concerns, along with a lack of awareness, fear of diagnosis, and social stigma, all of which contribute to delays in seeking timely care.

In many cases, women assume that the absence of symptoms indicates good health, which is a common but risky misconception.

Importance Of Routine Screening

Routine screenings such as Pap smears for cervical health, regular breast examinations, mammography where indicated, thyroid function tests, and basic metabolic screenings like blood sugar and cholesterol levels are critical tools in preventive care.

Periodic health check-ups also provide an opportunity for counselling on nutrition, mental well-being, hormonal health, and lifestyle management, areas that are often overlooked but equally important.

World Health Day serves as a reminder to shift from a reactive to a preventive approach. Prioritizing regular health check-ups, normalizing conversations around women’s health, and encouraging a culture of self-care can significantly improve outcomes. Investing in preventive healthcare is one of the most powerful steps women can take towards leading healthier, longer, and more empowered lives.

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