Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

Gastroesophageal reflux disease (GERD), commonly known as acid reflux, occurs when stomach contents flow backward into the esophagus, causing heartburn, regurgitation, chest discomfort, and sometimes chronic cough or hoarseness. This happens because the lower esophageal sphincter (LES), a muscle that normally prevents backflow, becomes weak or relaxes inappropriately, allowing acid to irritate the food pipe repeatedly. If left untreated, persistent reflux can lead to inflammation (esophagitis), ulcers, scarring, and in rare cases, pre-cancerous changes known as Barrett’s esophagus.

The global prevalence of GERD has been increasing in recent years, with around 14 % of adults worldwide affected according to recent meta-analyses. In India, community studies show notable rates, with higher prevalence in urban populations compared to rural areas and estimates ranging from about 8 % in some regions to higher figures in cities, reflecting shifting lifestyles. In Kolkata, according to Dr. Pradipta Sethy, Director, Gastroenterology, Manipal Hospital, EM Bypass and Mukundupur, the major patients are women, mostly pre-menopausal and menopausal, between the ages of 30-55 years. This rise can be attributed to several interconnected lifestyle and environmental factors.

One major contributor is dietary change. Traditional diets rich in fiber and whole foods are increasingly replaced by high-calorie, processed, and high-fat foods, along with frequent consumption of spicy and fried items. These foods can relax the LES and increase gastric acid production, making reflux more likely. In addition, habitual late-night meals followed by lying down soon after eating are common in urban settings and further promote reflux episodes.

Obesity and sedentary lifestyles are also important risk factors. Excess abdominal fat increases pressure on the stomach, forcing acid upward into the esophagus. Many adults with GERD in India and globally have overweight or central obesity, a trend growing alongside reduced physical activity. Stress and irregular eating patterns that accompany modern work life are additional contributors, often exacerbating symptoms and prompting unhealthy habits like caffeine or alcohol use, both of which can aggravate acid reflux.

Thankfully, GERD can often be managed effectively through simple lifestyle modifications. Eating smaller, more frequent meals and avoiding known trigger foods such as citrus fruits, chocolate, caffeine, and high-fat foods can reduce reflux episodes. Waiting 2–3 hours after eating before lying down and elevating the head of the bed during sleep helps keep acid in the stomach by using gravity to support digestion. Maintaining a healthy weight through regular physical activity reduces abdominal pressure, while quitting smoking and limiting alcohol intake supports LES function and esophageal health. Managing stress with techniques such as meditation or yoga further helps control symptoms by improving overall digestive function.

In conclusion, the rise of GERD in India mirrors global trends driven largely by dietary shifts, obesity, and modern lifestyle pressures. While medication is valuable for many patients, sustainable improvements often begin with these evidence-based lifestyle changes that address the root causes of acid reflux and improve long-term digestive health.

Rashes are common in children and can occur for many reasons. Most are harmless and settle on their own, but some may need medical attention. Knowing the warning signs can help parents decide when home care is enough and when to consult a doctor.

Why Do Rashes Happen?

Children’s skin is sensitive and can react to heat, friction, allergens, insect bites, irritants or infections. Common causes include heat rash, eczema, contact dermatitis, insect bites and viral infections such as chickenpox, hand-foot-and-mouth disease and roseola.

A rash can look worrying, but the child’s overall condition is often as important as the appearance of the rash itself.

When Home Care May Be Enough

If your child is active, reasonably comfortable, feeding and drinking well, and otherwise appears well, a mild rash can often be managed at home.

Home care may be appropriate when the rash:

• Is mild and limited to a small area
• Is not spreading quickly
• Causes only mild itching or discomfort
• Occurs without concerning symptoms
• Looks consistent with a known condition such as heat rash or eczema

Avoid applying multiple creams, powders, antiseptics or home remedies, as these may irritate the skin or make the rash harder to assess. Medicines or steroid creams should not be used without medical advice. Your paediatrician can recommend suitable treatment based on your child’s age, weight and the likely cause of the rash.

When Should You See a Doctor?

Seek medical advice if your child has:

• A rash with fever, particularly if the child appears unwell, unusually sleepy, less responsive or is becoming progressively worse
• A red or purple rash that does not fade or become lighter when pressed firmly with a clear glass, especially if the child has fever or appears unwell
• A rapidly spreading rash
• Large blisters, peeling skin or a painful/tender rash
• Signs of a secondary skin infection, such as increasing redness, warmth, swelling, pain or pus
• A new or unexplained rash in a newborn or young infant, especially if accompanied by fever, poor feeding or unusual sleepiness
• Unusual sleepiness, weakness, poor feeding or reduced drinking
• A rash that is getting worse, keeps recurring or does not improve with appropriate home care

Seek Emergency Care Immediately If

A rash is accompanied by:

• Difficulty breathing or swallowing
• Swelling of the lips, mouth, face or tongue
• Extreme sleepiness, marked weakness or a child who is difficult to wake
• Rapid deterioration in the child’s overall condition
• A concerning non-fading red or purple rash in a child who appears unwell

What Parents Should Remember

Most childhood rashes are temporary and harmless. However, it is important to look beyond the rash itself.

Note when the rash started, where it first appeared, whether it is spreading and whether your child has fever or other symptoms. A photo of the rash can also help your paediatrician understand how it has changed over time.

Trust your instincts. If your child seems unusually unwell, is getting worse or something simply does not feel right, it is always better to seek medical advice rather than waiting.

A Simple Rule for Parents

Home care may be enough if your child is well, active and comfortable. Seek medical attention if the rash is accompanied by significant illness, rapid worsening or any warning signs.

By Dr Navin Bhatia, Senior Consultant & HOD – Paediatrics & PICU, PB Health

India is facing a significant and growing cancer burden, with the latest National Cancer Registry Programme study estimating that the lifetime risk of developing cancer in the country is 11% — about one in nine people.

The 2025 study also found that India ranks second in Asia and third globally in cancer incidence.

SC Directs States To Notify Cancer

Around 17 states in India have already made cancer a notifiable disease, while the Supreme Court in August directed the remaining 19 states and Union Territories to comply with the requirement, aimed at enabling early detection and proper care of patients.

The petition before the court argued that the continued non-notification of cancer, despite its alarming and escalating burden in India, amounted to a grave abdication of the state's constitutional duty under Articles 14 and 21 of the Constitution. It said this denied uniform treatment to similarly situated citizens and undermined their fundamental right to health and a life of dignity.

The Supreme Court's order is legally binding on the remaining 19 states and Union Territories, which have until November 11, 2026, to comply with the directive.

By the deadline, the concerned administrations are required to transition cancer into a notifiable disease and formally submit their progress reports to the Supreme Court. States will also need to issue official Gazette notifications requiring public and private healthcare entities to report cancer cases and related data.

Why Cancer Notification Matters

Speaking to HealthandMe, experts said making cancer notifiable could strengthen cancer surveillance, improve data collection and support research and treatment planning.

Dr Karishma Kirti, Consultant Obstetrician & Gynaecologist, Jaslok Hospital, Mumbai, said cancer should be treated as a notifiable disease, but through a system different from the traditional notification process used for infectious diseases.

How Cancer Registration Can Help

Dr Kirti told HealthandMe that mandatory registration of cancer cases could help India understand cancer trends and generate more real-world data to guide research.

“Mandatory registration of cancer cases will in the future help in understanding trends, generating real-world data early, and guiding research. Most of the evidence-based medicine and treatment that we recommend comes from Western data and mandating cancer registration will help India generate its own data and understand the inherent characteristics of Indian cancers better.”

Notifying Cancer Could Strengthen Cancer Care

Dr Harit K Chaturvedi, CEO & Clinical Head, Apollo Oncology Network, said making cancer a notifiable disease could help improve cancer care and research as the country's cancer burden rises.

“No two cancers are the same and the disease cannot be fought in silos. As the burden of cancer cases is increasing, wherein India is projected to record 1.5 million cases in 2026, declaring cancer as a notifiable disease can enable better cancer care and research across India,” he told HealthandMe.

Chaturvedi said notification of cancer would also give impetus to the decades-old National Cancer Registry Program and enable proper and mandatory record-keeping of cancer cases, as seen in many developed nations.

“By making cancer a notifiable disease, we can ensure that all cancer cases are reported and documented accurately, enabling us to track cancer incidence, mortality, and survival rates.”

Importantly, he said, notification would also enable policymakers, healthcare providers and researchers to work with real-time data, which could help bring more awareness, strengthen prevention and early detection, and improve treatment outcomes and quality of life.