Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
Credits: Canva, PTI
As of 7am today, Delhi's average AQI was registered at 446 as per aqi.in. However, the Early Warning System for Delhi, under the Ministry of Earth Sciences, Delhi's average AQI at 7am was registered at 341, slightly better, still close to 400. Dr Shivanshu Raj Goyal, a pulmonologist and Associate Director Pulmonary Medicine at MAX Healthcare in Gurugram and Delhi, in an Instagram video said that breathing this toxic air is equivalent to smoking 20 cigarettes in a day.
The doctor starts his video with a rather strong statement, "At present, no one in Delhi-NCR is a non-smoker."
"With the AQI of around 400, if I break down the facts, with every 20 of an AQI of PM2.5, is equivalent to smoking a cigarette. So at the AQI of around 400, you are smoking easily 20 cigarettes a day. That is for everyone, each one of us, even a small change. So imagine the amount of damage that this AQI must be causing to your lungs," he says.
The doctor also states that on an average, a person breathes around 20,000 times in a day, so it means we are inhaling the toxic air at least 20,000 times a day.
As per Action on Smoking and Health (ASH), a cigarette contains nicotine, and tar, which is composed of chemicals like benzene, benzopyrene, and the gas includes carbon monoxide, ammonia, dimethyl nitrosamine, cadmium, formaldehyde, hydrogen cyanide and acrolein. Some of these marked irritant properties are also carcinogen, meaning, it can cause cancer.
Whereas Air Pollution contains pollutants like particulate matter PM 10 and PM 2.5, ozone, nitrogen dioxide, carbon monoxide, cadmium and sulfur dioxide. Air pollution, which is often a byproduct of combustion or released from vehicle exhaust also contain formaldehyde, benzopyrene, and benzene. As per the World Health Organization (WHO), the pollutants contain carcinogens, and the outdoor air pollution is in fact classified as Group 1 carcinogen.

Carbon Monoxide: a poisonous, flammable gas that is colorless, odorless, tasteless, and slightly less dense than air.
Benzene: a colorless and highly flammable liquid with a sweet smell, and is partially responsible for the aroma of gasoline.
Cadmium: a soft, silvery-white metal (atomic number 48) that is toxic and naturally found in the environment, but human activities have increased its levels. It is used in products like batteries, pigments, and coatings, and exposure can occur through tobacco smoke, contaminated food, and occupational inhalation. Cadmium is a known human carcinogen that can damage the kidneys and bones.
Formaldehyde: a colorless, flammable gas with a strong odor, whose exposure could cause cancer.
Benzopyrene: a group of organic compounds known as polycyclic aromatic hydrocarbons. It is a colorless crystalline solid found in sources like cigarette smoke, coal tar and is a known carcinogen that can cause cancer and other health problems like skin rashes and bronchitis, and exposure requires medical attention for any symptoms.
Dr Shivanshu Raj Goyal points out that these carcinogens could lead to long term lung and heart damage, as well ass cause chronic cough, breathlessness, asthma, and COPD. However, there are ways to protect yourself:
Credits: Canva
Contracting the flu, Covid-19, or similar viral infections can significantly raise the chance of serious heart problems, according to new research. A review of 155 academic studies by the Journal of the American Heart Association found that both influenza and Covid-19 may increase the likelihood of heart attacks or strokes by three to five times in the weeks following infection.
A comprehensive review in the Journal of the American Heart Association, which analyzed 155 studies, highlighted the following short-term cardiovascular risks compared with individuals who are not infected:
Influenza (Flu): Within the first month after a confirmed infection, the likelihood of experiencing a heart attack can increase up to fourfold, while the risk of stroke may rise fivefold. The greatest danger occurs during the first week.
COVID-19: Following infection, the risk of heart attack or stroke roughly triples within 14 weeks, and this heightened risk may persist for as long as a year.
Viruses that last longer in the body, such as HIV, hepatitis C, and varicella zoster (shingles), may also increase the long-term risk of cardiovascular issues. Published by the American Heart Association, the study underlines vaccination as a key way to reduce these risks, particularly for those already at risk of heart disease.
Lead author Associate Professor Kosuke Kawai from the University of California explained: "It is well recognised that viruses like HPV and hepatitis B can cause cancer, but the connection between viral infections and other non-communicable diseases, like cardiovascular disease, has been less clear. Our research found both acute and chronic viral infections are linked to short- and long-term risks of heart attacks and strokes."
The team systematically reviewed all published studies examining links between viral infections and heart attacks or strokes. Out of an initial 52,000 studies, only 155 met the strict criteria for design and quality. Findings revealed that the risk of a heart attack was four times higher and the chance of a stroke five times higher in the month after lab-confirmed influenza.
For Covid-19, individuals were three times more likely to experience a heart attack and three times more likely to suffer a stroke within 14 weeks of infection, with risks lasting up to a year.
People living with HIV had a 60% higher risk of heart attacks and a 45% higher chance of strokes over more than five years. Elevated risks were also observed for those who had hepatitis C or shingles.
Dr Kawai added: "While the long-term cardiovascular risks from HIV, hepatitis C, and shingles are lower than the short-term risk from influenza or Covid-19, they are still significant, especially because they last for years. Shingles alone affects about one in three people, which means a substantial number of excess cardiovascular cases at the population level."
Despite the results, the researchers noted limitations, as the study was observational rather than based on controlled trials. Nevertheless, the team highlighted vaccination as a potentially crucial tool for lowering heart-related risks.
Flu shots protect against influenza, which can be life-threatening for some groups. The NHS offers these vaccines each autumn or early winter to people most at risk of severe complications.
From September 1, six primary groups were eligible:
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From ground cinnamon to breakfast burritos, popcorn, and even pet food, food recalls in the U.S. seem to be appearing more often. Does this mean our food supply is becoming less safe? According to a report by compliance firm Sedgwick, the FDA and U.S. Department of Agriculture oversaw 294 food recalls in the first half of 2025. In the same period in 2024, the FDA had ordered the destruction of nearly 85 million units. USDA recalls impacted nearly 1.5 million pounds of food, almost three times more than last year.
Is this surge a sign that food production is failing, or does it reflect improvements in traceability? Perhaps the increase is due to better public access to information, allowing more recalls to be noticed. Or is U.S. food simply more contaminated than before?
The growing number of recalls has left shoppers worried about the safety of groceries. Experts, however, suggest that the increase doesn’t necessarily indicate declining food quality. Instead, it largely reflects advances in detecting contamination earlier and more efficiently.
As Lena Bakovic, MS, RDN, CNSC, from Live It Up explains, “The increase in the number of food recalls that we are seeing is likely largely due in part due to improvements in detection technologies, as well as generally stricter food safety testing requirements. Combined, these advancements help to provide earlier and more effective detection of potential contamination issues.”
Rather than showing a drop in quality, these recalls demonstrate that the system is working to protect public health. Improved testing and monitoring allow potential hazards to be identified and removed from shelves before reaching consumers.
In recent weeks, a number of U.S. food recalls have caught public attention. Over six million eggs from Black Sheep Egg Company were recalled due to possible salmonella contamination, impacting multiple states. Hormel Foods pulled nearly five million pounds of ready-to-eat chicken after metal fragments were discovered in food-service shipments. About 245,000 pounds of pre-cooked pasta, linked to a deadly listeria outbreak, were also recalled, causing several illnesses and deaths.
Frozen shrimp from various brands were removed over potential exposure to cesium-137, a radioactive isotope associated with cancer risk. More than two million pounds of Golden Island pork jerky were recalled after metal contamination was traced to a damaged conveyor belt. Additionally, ready-to-eat meals from meal-kit services like HelloFresh, Blue Apron, and Marley Spoon were pulled due to possible listeria contamination, which poses heightened risk to pregnant individuals, older adults, and immunocompromised people. Consumers are advised to discard or return affected products and consult healthcare professionals if needed.
Not all foods carry the same risk of contamination. Fresh produce, for example, is vulnerable because of its exposure during growth, harvesting, and transport. Packaged “ready-to-eat” meals can also be riskier because they bypass home cooking, a step that often eliminates harmful bacteria.
As Lena notes, “Some types of food are in fact more susceptible to contamination. Raw fruits and vegetables are examples of foods particularly in danger from microbial contamination due to their fresh condition, as well as exposure to potentially hazardous environmental influences. Additionally, food products which are commercially labelled and sold as ‘ready to eat’ can become more dangerous because they skip the at-home cooking process, which would likely eliminate any harmful pathogens in the first place.”
The health effects of eating recalled food depend on the contaminant. Bacteria like salmonella or E. coli can cause nausea, vomiting, and diarrhea, while chemical or allergen contamination may trigger allergic reactions or other toxic effects that aren’t immediately apparent.
“The health consequences can really vary depending on the root cause of the contamination,” Lena explains. “Bacterial pathogens like salmonella or E. coli can produce foodborne illnesses inducing gastrointestinal symptoms such as nausea, vomiting, and diarrhea. If a contaminant is a chemical or an allergen, allergy symptoms or other, potentially unknown, toxic effects are a possibility.”
Understanding recall classifications and keeping up with alerts can help protect your family from potentially harmful products.
In the U.S., food recalls are classified into three levels:
Class I: The most serious category, used when a product poses a significant health risk and could cause severe illness or even death. Examples include foods contaminated with bacteria like Salmonella or items with undeclared allergens.
Class II: Applies to products that may cause temporary or reversible health issues. For instance, yeast or mold contamination falls under this category.
Class III: The least serious, covering minor issues that are unlikely to harm but still break regulations, such as mislabeling—like placing a watermelon-flavored item in an apple package—without allergen concerns.
To stay updated, you can sign up for notifications on the FDA website or check Recalls.gov regularly. Be aware that alerts may include non-food products, so some filtering may be needed.
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