Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

End of Article

Preeclampsia May End With Pregnancy. Your Heart Risk May Not

Updated Sep 22, 2026 | 02:00 PM IST

SummaryPreeclampsia typically resolves after pregnancy, but it can signal higher long-term cardiovascular risk, making ongoing heart-health monitoring important for affected women.
Preeclampsia May End with Pregnancy. Your Heart Risk May Not

Credit: AI

Most women who've had preeclampsia remember it as something that happened during pregnancy. The blood pressure spiked, doctors kept a close watch, the baby arrived, and everything went back to normal.

Case closed, or so it seems. But there's a quieter part of this story that doesn't get told nearly enough - what preeclampsia might mean for a woman's heart years down the line.

So, What Is Preeclampsia?

It's a condition that can happen after the 20th week of pregnancy, when blood pressure rises sharply and starts putting pressure on organs like the kidneys or liver. During preeclampsia, the lining of blood vessels - the endothelium - becomes inflamed and doesn't relax and dilate the way it normally should.

This is the same vessel dysfunction we see in the early stages of coronary artery disease, just decades ahead of schedule. Doctors usually catch it through routine checks - protein in the urine, sudden swelling, or blood pressure readings that don't sit right.

Once the baby is delivered, blood pressure almost always comes back down. That "return to normal," though, doesn't mean the story is over.

Also read: Vitamin D & Pregnancy: Could Vitamin D Deficiency Increase Risk Of Premature Birth?

A Pregnancy Complication with a Long Impact on Heart

Think of preeclampsia as an early stress test that the heart didn't quite pass. It is associated with increased risk of hypertension in future and also increase the risk of heart failure, stroke and cardiovascular diseases. And this isn’t a risk that shows up only in old age, in some cases, death happens within the first 10 years after pregnancy.

The risk of heart failure also increases by four-fold and the risk of coronary heart disease by two folds in patients with preeclampsia. The risk of ischemic heart disease and hypertension is elevated too. The risk increases further if preeclampsia occurred early in pregnancy, during multiple pregnancies, or alongside other factors like obesity or a family history of heart disease.

It highlights the importance of life law monitoring of cardiovascular rest factors in a woman who has history of preeclampsia.

Also read: PMOS Isn't Just About Periods Or Pregnancy: Why Women Need To Think Beyond Fertility

The Part of Care That Often Gets Skipped

Once the baby is here, attention naturally shifts entirely toward the newborn - and a new mother's own follow-ups tend to fall away quietly, usually right after that standard six-week check. That's the gap, we need to close in postpartum care. Women with a preeclampsia history should regularly monitor their blood pressure, cholesterol and blood sugar, and actually bring these numbers up during the consultation.

None of this means preeclampsia guarantees heart disease down the road. It just means the risk picture has shifted, and that's worth knowing. Staying active, eating well, keeping weight in check, and staying away from smoking helps reduce the risk.

More obstetricians and cardiologists are starting to treat preeclampsia as something to track for life, not just for nine months. That shift in thinking could end up protecting a lot of hearts long after the pregnancy itself is over.

By Dr Waseem Farooqui, Consultant, Interventional Cardiology, Cardiac Care, Medanta Hospitals, Noida

End of Article

Is Controlling BP Enough After a Brain Bleed? Doctors Explain How to Prevent Another Stroke

Updated Sep 22, 2026 | 01:00 PM IST

SummaryAfter a brain bleed, consistent BP control, medication, lifestyle changes and follow-ups are crucial. Neurologists explain warning signs and when sudden BP rises need urgent care.
Is Controlling BP Enough After a Brain Bleed? Doctors Explain How to Prevent Another Stroke

Credit: AI Generated Image

After a brain bleed, controlling blood pressure is crucial—but is it enough to prevent another stroke? Neurologists explain why consistent BP monitoring, regular medicines, lifestyle changes, and follow-ups matter after discharge. They also share warning signs families should never ignore and when sudden BP rises require urgent medical attention.

Is Blood Pressure Control Enough After A Brain Bleed?

Dr Shubha Subramanian - Senior Consultant - Neurology - Kauvery Hospital, Vadapalani, Chennai told Health and Me, "After a brain bleed, controlling BP is extremely important, but this is only for spontaneous intracerebral haemorrhage, not in cases of an AV malformation, an aneurysm-related bleed, or a traumatic bleed, where the aetiology is different." He added, "In case of idiopathic spontaneous intracerebral haemorrhage, probably because of BP fluctuations or high BP, in that case, for secondary prevention, there will be a reduced number of bleeds if the BP is well controlled. Consistent control is very, very important."

After a brain bleed, patients should regularly monitor blood pressure and pulse, with diabetics also checking blood sugar at home. Periodic blood tests and ECGs may be advised. Families should watch for confusion, seizures, weakness, changes in speech, or facial drooping. Recognising these warning signs early and maintaining consistent BP control can help prevent another bleed.

The Common Mistakes That Can Raise The Risk

"Common mistakes include missing medications, not monitoring blood pressure regularly, stopping follow-up visits when they are feeling better, smoking and consuming too much alcohol, and returning too soon to strenuous activity," said Dr. Soniya Tambe, Consultant, Neurology, Fortis Hospital, Bannarghetta Road, Bengaluru. She added, "Patients also may ignore symptoms such as severe headache, weakness, speech difficulty, or vision changes. These signs should never be dismissed."

What To Eat And Avoid During Recovery

Recovery after a brain bleed doesn’t stop when a patient leaves the hospital. The steps taken at home are equally important in reducing the risk of another stroke. Along with taking medicines as prescribed and keeping blood pressure under control, patients should focus on making healthy, long-term lifestyle changes rather than following temporary restrictions.

A balanced, low-salt diet can support recovery, while smoking and alcohol should be avoided. Patients should ease back into physical activity gradually and only with their doctor’s advice, especially in the early recovery period. Getting enough sleep, maintaining a healthy weight, and managing stress are also important. Regular follow-ups help monitor blood pressure and other heart-related risk factors.

Warning Signs Families Should Never Ignore

Dr. Praveen Chander, Senior Consultant Neurology, Gleneagles Chennai, told Health and Me, "Families should also recognise sudden weakness or numbness, difficulty speaking, confusion, loss of balance, severe headache, or sudden vision changes as possible warning signs. These symptoms require immediate medical attention rather than waiting for them to settle."

End of Article

US Gen Z, Millennials Are Drinking Less Alcohol For First Time Since COVID-19

Updated Sep 22, 2026 | 11:46 AM IST

SummaryAlcohol use among Gen Z adults fell by more than 5%, millennials also recorded a drop in heavy drinking, at 17% between 2022 and 2024. In contrast, alcohol use increased among adults aged 50-64 by nearly 4%, while heavy drinking increased by more than 36%.
US Gen Z, Millennials Are Drinking Less Alcohol For First Time Since COVID-19

Credit: iStock

Alcohol use among US adults has declined for the first time since the COVID-19 pandemic began, driven largely by Gen Z and millennials, a new study found.

However, alcohol use remains above pre-pandemic levels, according to the findings published in the Annals of Internal Medicine.

"It’s encouraging to see alcohol use decline for the first time since the start of the pandemic,” said Brian P. Lee, a hepatologist and liver transplant specialist with Keck Medicine at the University of Southern California and principal investigator of the study.

“However, use remains above pre-pandemic levels and certain groups continue to have concerning trends," he added.

What Did The Study Find?

Researchers analyzed National Health Interview Survey data from 114,352 US adults between 2018 and 2024.

Heavy drinking was defined as five or more drinks per day or 15 or more drinks per week for men, and four or more drinks per day or eight or more per week for women, in the 12 months before the survey.

From 2022 to 2024, any alcohol use fell by nearly 2%, while heavy drinking declined by more than 8%.

Researchers said this was the first confirmed reduction in alcohol consumption since the pandemic began, following increases in drinking reported in previous studies.

Gen Z, Millennials Cut Back As Older Adults Drink More

The biggest decline in any alcohol use was among Gen Z adults, whose consumption fell by more than 5%.

Millennials recorded the largest drop in heavy drinking, at 17% between 2022 and 2024.

The study did not examine why younger adults reduced their drinking, though researchers noted that changing social attitudes toward alcohol may be one explanation.

In contrast, alcohol use increased among adults aged 50-64. From 2018 to 2024, any alcohol use in this group rose by nearly 4%, while heavy drinking increased by more than 36%.

According to Lee, the increase is particularly concerning because older adults face higher risks of alcohol-related conditions, including liver disease, certain cancers and cardiovascular disease.

"Heavy drinking among ages 50-64 is up by more than a third since 2018, a concerning trend because this age group faces some of the greatest risks of harm from alcohol, including cirrhosis and alcohol-related cancers,” Lee said.

Men saw a larger decline in any alcohol use than women, 2.4% versus 1.1%. However, heavy alcohol use fell more among women than men, 9% versus 7.7%.

Lee noted that understanding differences in drinking patterns could help develop more effective prevention and treatment strategies.

Does Drinking Less Reverse Alcohol-Related Harm?

Excessive alcohol consumption is one of the leading preventable causes of illness and death in the US, according to the Centers for Disease Control and Prevention.

Alcohol accounts for approximately half of all liver-related deaths, while alcohol-associated cirrhosis has become the leading cause of liver transplants, according to Lee.

The World Health Organization says health risks begin with the first drop of alcohol, meaning no level of consumption is completely safe or risk-free.

Although the decline in alcohol use is a positive development, "we cannot assume alcohol-related harms will decline automatically,” said Lee. “Continued attention to screening, prevention and treatment will be critical, particularly among groups where alcohol use remains elevated.”

End of Article