Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

Every year on October 2, World No Alcohol Day urges people to pause and think about alcohol's place in everyday life. Here's where the day came from, and what current research actually shows about drinking.

World No Alcohol Day: Origins

It began in 2008, when India's then Union Health Minister, Dr. Anbumani Ramadoss, proposed a global alcohol-free day at the World Health Assembly in Geneva, according to National Day Calendar. The proposal drew support from 11 Southeast Asian countries.

The World Health Organization never formally adopted October 2 as an official global observance, according to a summary on Checkiday. There are, in fact, three dates tied to alcohol awareness worldwide: October 2 and October 3, observed by many groups as World Alcohol-Free Day or World Temperance Day, and November 15.

In India, October 2 is also a nationwide dry day, with no alcohol sales permitted, and is marked separately as National Anti-Drug Addiction Day.

Also Read: Does Experimental Obesity Drug Petrelintide Cause Fewer GI Side Effects Than Ozempic? Lancet Study Shows Promise

What Science Says About Alcohol Now

The science has shifted since 2008. In January 2023, the World Health Organization stated plainly that no level of alcohol consumption is safe for health, publishing the position in The Lancet Public Health. The WHO said current evidence cannot identify any threshold below which alcohol's cancer-causing effects switch off.

Alcohol is classified as a Group 1 carcinogen, the same risk category as tobacco and asbestos, and is linked to at least seven types of cancer, including the most common cancers in men and women, bowel and breast cancer, according to the WHO.

Globally, alcohol was responsible for an estimated 741,300 new cancer cases and contributed to nearly 400,000 cancer deaths in a single year, as per Lancet-based estimates cited by the Union for International Cancer Control.

Previous research has showed some benefits of wine, but the majority scientific consensus now is that there is no safe levels of alcohol. The World Health Organization says health risks begin with the first drop of alcohol, meaning no level of consumption is completely safe or risk-free.

The toll beyond cancer

Cancer isn't the only risk. Alcohol use is tied to roughly 2.5 million deaths worldwide each year, including 320,000 among people aged 15 to 29, according to the WHO. Beyond individual health, alcohol-related harm also means more road accidents, violence, and strain on healthcare systems.

A May 2026 study linked alcohol to 62 disorders, ranging from heart and digestive diseases to mental and neurological conditions and cancers.

The study, published in the journal Addiction, showed that the fully alcohol-attributable conditions are mainly grouped under non-communicable diseases and injuries.

These include:

• Endocrine, nutritional, and metabolic diseases
• Mental and behavioral disorders
• Diseases of the nervous system
• Diseases of the circulatory system, such as alcoholic cardiomyopathy
• Digestive diseases
• Alcoholic liver disease and cirrhosis.

The data also included psychotic disorders, gastritis, ulcers, pancreatitis, fatty liver disease, pregnancy- and perinatal-related conditions such as fetal alcohol syndrome and fetal alcohol spectrum disorders, as well as external causes and injuries, including alcohol poisoning.

Excessive alcohol consumption is one of the leading preventable causes of illness and death in the US, according to the Centers for Disease Control and Prevention.

Research shows that alcohol accounts for approximately half of all liver-related deaths, while alcohol-associated cirrhosis has become the leading cause of liver transplants.

Actress Amanda Peet has opened up about her breast cancer diagnosis, revealing a “weird” change in the skin that did not feel like the typical lump many people associate with breast cancer.

A breast lump is a well-known warning sign of breast cancer, but the disease can also cause changes in the breast’s skin, shape or texture. This makes it important to pay attention to changes that may not feel like a distinct lump.

What Did Amanda Peet Feel?

Peet, 54, recalled noticing something unusual while getting dressed.

“I was in my closet, I was probably putting something on and I felt a weird — it just didn’t feel like normal skin, but it wasn’t the frozen pea that everybody talks about,” she told Today.com.

Peet described the sensation as a change in how the skin felt rather than a clearly defined lump.

Other breast cancer warning signs can include changes in breast size or shape, skin dimpling, swelling, redness, nipple changes or unusual discharge. Skin that becomes pitted and resembles an orange peel, known as peau d’orange, can also be a warning sign.

Importantly, breast cancer can sometimes be present without an obvious lump.

Peet had been undergoing regular breast screening and follow-up because of her breast health history. She has said that an MRI did not show the cancer, but a subsequent ultrasound detected an abnormality. A biopsy later confirmed a tumor.

She was diagnosed with hormone-receptor-positive, HER2-negative invasive lobular carcinoma and underwent a lumpectomy followed by radiation.

What Is Invasive Lobular Carcinoma?

Invasive lobular carcinoma (ILC) is the second most common type of invasive breast cancer and accounts for about 10% of invasive breast cancers.

Unlike many breast cancers that form a distinct lump, ILC can grow in a more diffuse pattern. It may cause thickening, fullness or a subtle change in the breast rather than a clearly defined mass.

Because of the way ILC grows, it can sometimes be harder to detect on mammography. Additional imaging, including ultrasound or MRI, may be used depending on an individual's symptoms, breast density and clinical assessment.

Most invasive lobular cancers are hormone-receptor positive. Peet wrote that she had been seeing a breast surgeon every six months for checkups. Her cancer was diagnosed at Stage 1.

“I think about how lucky I was in so many ways,” she said.

Why Early Detection Matters

Breast cancer screening is designed to detect cancer before signs or symptoms become apparent. The goal is early detection, when treatment may be more effective.

The appropriate screening schedule depends on age, breast cancer risk, family history and other factors. In the US, the US Preventive Services Task Force recommends that women at average risk aged 40 to 74 have a mammogram every two years.

People with a higher risk of breast cancer may need a different screening approach or additional imaging. Discussing individual risk and screening options with a healthcare professional can help determine what is appropriate.

October Is Breast Cancer Awareness Month

October marks Breast Cancer Awareness Month, with this year’s theme, “Every story is unique, every journey matters,” highlighting that every breast cancer experience is different.

According to the World Health Organization (WHO), breast cancer is the most common cancer among women. About 80% of breast cancers occur in women with no specific risk factors other than sex and age.

In 2024:

• 2.4 million women were diagnosed with breast cancer worldwide.
• 694,000 women died from the disease.
• 8.2 million women were living with breast cancer at the end of the year.

After eliminating measles in 2000, the US is now seeing a sharp increase in cases, with 3,659 confirmed cases reported as of September 24, 2026. Pennsylvania has reported five measles-related deaths this year, the first such deaths in the state in 35 years.

The number has risen significantly from previous years. The US reported 2,289 cases in 2025, compared with 285 in 2024 and just 85 cases in 2000.

Measles can cause serious complications, including pneumonia and encephalitis, or brain swelling, and can be fatal.

Two doses of the measles, mumps and rubella (MMR) vaccine can prevent measles by up to 97%, although breakthrough infections can still occur.

Around 95% of reported cases have been among unvaccinated people, although breakthrough infections have also been reported among people who were fully vaccinated. However, measles is not expected to be as severe in people who are vaccinated.

“Their illness will be much more mild and less likely to cause serious illness than if they had not received two vaccines,” Dr. Pia Fenimore, chief and vice chair of pediatrics at Penn Medicine Lancaster General Health.

Yet according to experts some people can take a booster shot to stay safe.

Who May Need a Measles Booster?

The first measles vaccine was introduced in the US in 1963, but the formulation used between 1963 and 1967 was less effective than current versions.

Adults vaccinated during that period may need another dose if they have not received a later measles vaccine.

People born before 1957 are generally considered to have presumptive evidence of immunity because measles circulated widely before routine vaccination, and most people in this age group were naturally infected.

Some people may need individualized vaccination guidance rather than standard recommendations, including:

• People with uncertain vaccination status or no vaccination records
• People who received an inactivated measles vaccine between 1963 and 1967
• People with a weakened immune system
• Pregnant people

A measles vaccine booster may also be considered for children who received only one MMR dose, high-risk adults such as healthcare workers or international travelers, and people whose testing shows they lack immunity.

Can A Blood Test Check Measles Immunity?

In cases where people do not remember or have no records of two-dose measles vaccination, an Immunoglobulin G (IgG) antibody test can help assess whether they have antibodies against measles.

If testing shows sufficient measles IgG antibodies, the person is considered immune. If immunity is not established, vaccination may be recommended based on their individual circumstances.

Why Adults Also Need To Be Alert

Measles is often associated with children, but adults can also become infected.

“We often forget about adults getting measles ... 38% to 40% of cases this year of measles have been in adults. Adults become infected at the same, if not higher, rates than children themselves ... in 2025, just over half of the measles hospitalizations were actually ... adults,” Dr. Gavin Harris, an infectious diseases physician with Emory Healthcare in Georgia and the associate medical director of the Serious Communicable Diseases Unit.

What If You Were Exposed To Measles?

Measles is highly contagious and can spread through even limited exposure to the virus. With the virus outbreak, it is likely for people to get exposed to it.

The measles vaccine remains the absolute best way to prevent disease.

A shot within three days of exposure to the contagious virus can help prevent the disease. Intravenous immunoglobulin (IVIG) given within six days can also provide protection after exposure.