Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
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Yoga can act as a "polypill" by addressing multiple underlying factors that contribute to lifestyle diseases, according to Dr. Rima Dada, Professor at the All India Institute of Medical Sciences (AIIMS), who has been studying yoga and its impact on lifestyle disorders for the past 20 years.
Speaking about her research, Dr. Rima said yoga is a profound science, technology, and art of living that can tackle factors that set the stage for a wide range of diseases.
According to Dr. Rima, yoga can help address conditions including hypertension,
Also read: Yoga Enriches Every Aspect of Life, From Fitness to Inner Peace, Says PM Modi
Dr. Rima said evidence-based studies conducted by her team have shown that yoga addresses these underlying factors.
According to the findings, yoga reduces oxidative stress by increasing the expression of various antioxidants. It also improves mitochondrial health and reduces free radicals produced as by-products of ATP production.
The studies further showed that inflammation decreases because the expression of genes coding for anti-inflammatory factors increases, while the expression of genes that promote inflammation declines.
The research also found that yoga increases the expression of genes involved in DNA repair. In addition, yoga promotes parasympathetic dominance, resulting in increased rest, repair, and digestion.
Dr. Rima said yoga also positively modulates the epigenome and increases the expression of factors beneficial for overall health. She noted that yoga promotes brain health, improves mental well-being, and enhances the production of factors associated with neurogenesis in key areas of the brain. These changes may help improve memory and build emotional resilience.
Read More: Trying to Quit Tobacco? Yoga Could Improve Your Chances, Suggests Study
Dr. Rima said yoga has also been shown to improve gut microbial flora, helping maintain the integrity of the gut-brain axis.
According to her, this supports the secretion of factors that help maintain immune, endocrine, and mental health.
Emphasizing that yoga extends beyond physical postures, Dr. Rima said it is an entire lifestyle that includes diet, asanas, pranayama and dhyana.
She said yoga and asanas help bring the body into proper geometry and alignment, while also improving flexibility, range of motion and neuromuscular coordination.
This alignment, she explained, enables more effective breathing. Nasal inhalation and exhalation activate certain areas of the brain that promote a state of relaxed wakefulness.
Dr. Rima said effective breathing increases blood flow to the brain and raises nitric oxide levels, which help improve circulation while reducing inflammation and oxidative stress.
"Thus, yoga is a polypill and is the need of the day," she said.
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Heavy menstrual bleeding caused by fibroids and other gynecological conditions is a major but often overlooked contributor to anemia among Indian women, said Dr. Roma Sinha, Chief Gynecologist and Director of Gynecological Robotic Surgery at Apollo Hospitals, Hyderabad, today.
Speaking at the Times Network India Health Summit 2026 at Hyderabad, Dr. Sinha highlighted how many women normalize excessive menstrual bleeding and delay seeking medical attention, often leading to severe anemia and a reduced quality of life.
According to Dr. Sinha, it is not uncommon for women to visit her clinic with hemoglobin levels as low as five or six grams per deciliter.
"Most of the time, it is not nutritional anemia. Women lose so much blood during their menstrual cycles that they are unable to rebuild their hemoglobin levels," she said.
While national programs such as Anemia Mukt Bharat focus heavily on pregnant women, Dr. Sinha pointed out that anemia occurring during other stages of a woman's life often goes unnoticed.
She said many women learn from family members and friends that heavy bleeding is "normal" and simply continue to suffer without seeking treatment.
Also read: Violence Against Doctors Is A National Concern, Says IMA Dilip P. Bhanushali
Beyond the underlying disease, Dr. Sinha emphasized the impact heavy menstrual bleeding has on women's daily lives.
"Many women think they are tired because of stress, work, or family responsibilities. But often it is low hemoglobin and iron deficiency causing that fatigue," she said.
The expert noted that a simple hemoglobin test can help diagnose anemia, yet many women continue to prioritize the health of their families over their own well-being.
Dr. Sinha identified lack of awareness and negligence as two major reasons why women delay medical consultations.
"Heavy bleeding occurs only for a few days every month, so women tend to tolerate it and move on. Many don't realize that it is treatable and that ignoring it can lead to dangerously low hemoglobin levels," she said.
The expert stressed the need for greater public awareness and open conversations about menstrual health.
"It should not be a taboo to talk about heavy menstrual bleeding," she added.
Read More: Childhood Obesity Is A 'Do or Die' Crisis, Experts Warn
A common fear among women, Dr. Sinha said, is surgery. Many patients avoid consultations because they assume treatment will automatically mean a hysterectomy —the surgical removal of the uterus— after which pregnancy is impossible, the top gynecologist said. However, she clarified that surgery is not the only option available for fibroids.
"Fibroids are largely benign tumors. Women today have choices, including medical management, non-invasive treatments, myomectomy, or hysterectomy, depending on their individual needs and preferences," she said.
The expert added that modern technologies such as robotic surgery have significantly improved outcomes for women requiring treatment.
Dr. Sinha also highlighted long-term research conducted on women who underwent robotic surgery for fibroids.
"We followed patients for ten years and found that 86.3 per cent conceived and delivered successfully after surgery," she said.
The findings, she noted, should reassure younger women concerned about fertility after fibroid treatment.
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While early detection cannot eliminate fibroids completely, Dr. Sinha said it can prevent severe anemia and improve overall quality of life. "Current treatments can control symptoms and act as bridge therapies, helping women avoid complications and delay more definitive treatment when appropriate," she explained.
In her message to women, Dr. Sinha urged them to listen to their bodies and seek help when they notice abnormal menstrual bleeding.
"If you feel your periods are heavier than normal, don't ignore it. Get a simple hemoglobin test and consult a gynecologist," she said.
Dr. Sinha also called on families, particularly men, to support women in seeking care and to pay attention when they complain of persistent fatigue or excessive menstrual bleeding.
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Violence against healthcare professionals is no longer just a workplace issue but a national concern that threatens the very foundation of India's healthcare system, said Dr Dilip Bhanushali, Immediate Past National President of the Indian Medical Association (IMA), at the ongoing Times Network India Health Summit 2026 in Hyderabad.
Addressing a session on Building Trust in Healthcare: Addressing Violence Against Healthcare Professionals, the expert highlighted the alarming rise in attacks on doctors, nurses, and other healthcare workers, calling for urgent legal reforms, stronger security measures, and a renewed effort to rebuild trust between patients and medical professionals.
Drawing attention to the scale of the problem, the Dr Dilip said studies show that more than 60 per cent of healthcare workers in India have experienced some form of violence, with verbal abuse being the most common. Emergency departments continue to be among the most vulnerable areas for such incidents.
"Behind every statistic is a doctor who went home shaken, a nurse who cried silently after a night shift, or a medical student questioning their future in the profession," he said.
The growing normalization of violence against healthcare workers, he warned, is one of the most worrying aspects of the crisis.
Dr. Dilip noted that while doctors are often celebrated when treatments succeed, they frequently become targets when outcomes are unfavorable despite their best efforts.
"Medicine is not mathematics. Not every illness can be cured, not every complication can be predicted, and not every life can be saved," he said.
While emphasizing that accountability and transparency are essential when mistakes occur, the expert stressed that violence can never be justified. "A complication is not necessarily misconduct, and a bad outcome is not necessarily a crime," he added.
Also read: Childhood Obesity Is A 'Do or Die' Crisis, Experts Warn At Times Network India Health Summit 2026
Calling trust the foundation of effective healthcare delivery, Dr. Dilip said the erosion of trust between patients and doctors has serious consequences for the entire healthcare ecosystem.
"Without trust, every prescription is questioned, every diagnosis is doubted, and every conversation becomes a confrontation," he noted.
The Indian Medical Association has consistently maintained that violence against healthcare workers is not merely an attack on an individual doctor but on the healthcare system itself, he added.
The IMA leader reiterated the association's long-standing demand for a comprehensive central law to protect healthcare personnel and institutions.
While acknowledging that several states have enacted legislation against violence towards healthcare workers, they argued that enforcement remains inconsistent.
The association is seeking stricter penalties, mandatory registration of cases, speedy investigations, and time-bound prosecution of offenders.
"Laws on paper alone cannot protect healthcare workers. Enforcement is equally important," Dr. Dilip said.
Beyond legislation, Dr Dilip said called for practical measures to improve safety within healthcare facilities.
Recommendations included regular security audits, adequate CCTV coverage, trained security personnel, emergency response systems, and controlled-access areas within hospitals.
"No healthcare professional should fear for their safety while caring for patients," he said.
"The future of healthcare cannot be built on fear; it must be built on trust," Dr Dilip said.
Healthcare professionals, he added, continue to serve despite long hours, emotional strain, and personal sacrifices, and deserve both protection and respect.
"Protect the healer, and you protect healing itself," Dr Dilip said.
The ongoing Times Now India Health Summit 2026 – South Edition in Hyderabad is bringing together leading voices from government, medicine, research, and the healthcare industry to discuss the future of India's healthcare system.
The summit featured renowned doctors, policymakers, hospital leaders, researchers, and healthcare innovators, with discussions spanning preventive healthcare, artificial intelligence, women's health, public health policy, and medical innovation.
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