Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

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Highlighting the importance of getting screened, surgeon Christine Lai reveals a key stage of breast cancer that most people do not know about.
Breast cancer is one of the leading cancer diagnoses for women throughout the world. But it is also a highly treatable type of cancer if found early. While most of us know that breast cancer symptoms like lumps in the breast or discharge from the nipples, these symptoms come when the cancer is already progressing to an advanced stage.
The University of Kansas Cancer Center explains that there could be a palpable lump or tenderness, but generally breast cancer has no symptoms in the early stage. But is this stage 1, or stage 2? Which early stage cannot be accurately diagnosed with self-examination.
In a recent post, Dr Christine Lai, Specialist Surgeon based in Australia, details the key stage people do not know about and its not 1 or 2, its stage 0.
Dr Lai explains that stage 0 is the very first and most treatable stage of breast cancer. At this point, no actual lump has formed, and the person usually has no symptoms.
The cancer cells are only sitting inside the milk ducts, where they are growing but have not yet developed the ability to break out and spread into the surrounding breast tissue.
This specific type of cancer is often called Ductal Carcinoma In Situ (DCIS). If we find cancer at this stage, it is almost certainly curable. This is why getting a routine screening mammogram is so crucial—it can catch this hidden stage and save a life.
In the video, Dr Lai details how big the tumor is during each stage, and how is it different from the previous stage, along with their treatability.
Stage 1 cancer means the tumor is quite small and is mostly confined to the breast. The tumor is usually 2 cm or less in size, which is smaller than a cherry. At this point, the cancer either hasn't spread to the lymph nodes at all, or the spread is extremely minimal and only visible under a microscope. Because the cancer is so small and localized, Stage 1 is highly treatable.
Stage 2 means the cancer is either moderately sized or has started to involve a few nearby lymph nodes. This stage applies if the tumor is smaller than 5 cm but has spread to up to three lymph nodes. It also applies if the tumor is larger than 5 cm but hasn't yet spread to any lymph nodes at all. Think of this as the cancer becoming more established, either by growing larger in one spot or starting to spread slightly to the closest glands.
Stage 3 indicates that the cancer has become more aggressive locally, involving more lymph nodes or invading nearby tissues. This applies if there are more than three involved lymph nodes, or if the tumor is invading the chest wall or the skin of the breast. A special type of cancer called inflammatory breast cancer is also classified as Stage 3 because of how it spreads across the breast tissue. This stage requires more intensive treatment because the disease has spread more extensively in the chest area.
Stage 4 is when the breast cancer has spread from the breast and armpit to distant parts of the body, such as the bones, lungs, liver, or brain. This is also known as metastatic breast cancer. While this stage is generally not curable, it is still highly treatable. Treatment focuses on controlling the cancer, relieving symptoms, and allowing the patient to maintain the best possible quality of life.
Credits: ANI
As air quality in Delhi continues to worsen, the visibility has also been impacted. In fact, the national capital's major landmarks, including the India Gate has been shrouded in thick smog. As a result, many are now reporting with breathing issues, however, the air quality's condition worsening impacts more than just lungs and respiratory system.
"Air pollution is eating into our bodies just like termites eat into wood," says Dr Arvind Kumar, Thoracic Surgeon and Lung Health Specialist at Medanta Hospital to ANI.
He highlights that the air pollution does not only impact the lungs, but also the IQ of the kids, non-smokers and their risk of cancer, and life expectancy.
Dr Kumar notes that air pollution can now also reach fetus through mother's placenta. The way nutrients reach the womb to the baby, the pollutants, thanks to its minute size could travel through blood and reach to the babies. "IQ in kids are low," says Dr Kumar. As per a UNICEF report, toxic air lowers children's IQ and memory and affects their test scores and also triggers neurological deficit hyperactivity disorder. It further leads to development delays.
The report has estimated 17 million babies worldwide, with around 12 million living in South Asia, live in areas that record pollution levels six times higher than the international safe limits of 20 micrograms per cubic meter for PM 10 and 10 microgram per cubic meter for PM 2.5.
This brings us to Dr Kumar's next point, on how these particulate matters are now leading to lowering life expectancy.
Dr Kumar says that the overall life expectancy of an average adult is also going down by 3 to 4 years.
"We breathe on an average for 25,000 times a day, and end up inhaling 10,000 liters of air. While 20% of which is oxygen, we also inhale unwanted particles, which are some seriously disease causing chemicals including PM2.5," he says.
He further notes that while there has been discrepancies in the PM2.5 levels and overall pollution levels in the national capital, it could be agreed that on an average the AQI remains over 300.
However, in 100 AQI, there are around 22 microgram of PM2.5, which is equivalent to 1 cigarette. So, if a person breathes in 300 or above AQI, then the person is inhaling smoke equivalent to 15 to 20 cigarettes.
Which brings to the third most important point the doctor noted, which is the ending difference between the lungs of smokers and non smokers.
"Earlier we had 90% of lung cancer patients who smoked, and 10% were non smokers. Now, it is 50-50," says the doctor.
The doctor noted that due to the toxic air that everyone is inhaling, now there is no difference between the cancer risk between a smoker and a non smoker. In fact, as per the data, nearly 1 in 4 adults who smoke, among them, more than one-third are men, while women are only 8%. However, the doctor notes that there is no difference between a woman's and a man's risk for lung cancer, even though the data shows that less women smoke, all thanks to the toxic air pollution.
The safety precautions that time and again many doctors have said include:
Credits: Canva
A recent paper in The Journal of Nutrition reports that there is promising, although still developing, scientific evidence linking regular yogurt intake with a lower chance of developing type 2 diabetes (T2D). These findings supported the Food and Drug Administration’s 2024 decision to permit a qualified health claim for yogurt.
The agency stated that steady yogurt consumption appears to be tied to reduced T2D risk and that the new claim can help guide public messaging to encourage people to eat more yogurt, which also raises intake of nutrients many people lack, such as calcium. To understand this connection more clearly, we spoke with Prof. (Dr.) Supriya Awasthi, Dean and Professor at the School of Allied Health Sciences, Noida International University.
Type 2 diabetes is a long-term condition in which the body does not make enough insulin or does not respond to it properly. This leads to high blood sugar levels that gradually damage nerves, blood vessels, and several organs. It is the most widespread form of diabetes. According to the Mayo Clinic, it can often be delayed or prevented by staying active and maintaining a healthy weight.
Yogurt, a simple and widely consumed dairy food, has attracted attention for its possible protective effect. Fermented foods like yogurt contain helpful bacteria known as probiotics. These bacteria support gut health. Research on the gut is still progressing, but scientists now believe the balance of gut bacteria may affect many health concerns, including obesity and diabetes.
Since type 2 diabetes is one of the most common lifestyle-related disorders worldwide, experts continue to study how daily food choices shape its risk. But can a weekly serving of yogurt truly matter? Dr Supriya said that it can, especially when yogurt is part of an overall balanced eating pattern.
Yogurt offers probiotics that help keep the gut microbiome in good condition. A healthy gut environment supports better metabolism, lowers inflammation, and improves how the body handles glucose. Ongoing inflammation and poor gut balance are well-known contributors to insulin resistance, which is the driving factor behind type 2 diabetes. According to Dr Supriya, regular yogurt intake may ease these problems and help the body manage blood sugar more effectively.
She also explained that yogurt’s protein content and naturally low glycemic index offer added advantages. She said, “Protein keeps you satisfied longer and helps curb sudden cravings. Foods with a low glycemic index do not raise blood sugar quickly. This can help prevent spikes in insulin and reduce the chances of developing insulin resistance over time.”
Several studies show that people who include plain or low-fat yogurt in their weekly meals tend to manage their weight better, which is an important part of lowering diabetes risk.
Yogurt is not harmful for people with diabetes, but choosing the right kind is essential. Many flavored or sweetened yogurts contain large amounts of added sugar, which can raise the risk of diabetes complications. The best choices are plain, unsweetened, low-fat, or Greek yogurt. These provide strong nutritional value without unnecessary sugar. Adding fruits, nuts, or seeds can improve taste in a healthy way.
Dr Supriya said, “While yogurt can support better metabolic health, it should not be viewed as a cure on its own. Its benefits are strongest when combined with a healthy routine that includes regular physical activity, weight control, fiber-rich meals, and limited sweets.” Even so, having yogurt two to four times a week may help maintain steadier blood sugar and lower long-term risk for type 2 diabetes.
Eating yogurt each week can be a simple and useful step in a diabetes-prevention plan. Its probiotics, protein, and gentle effect on blood sugar make it a valuable food for metabolic wellbeing. By choosing plain, low-sugar varieties and pairing them with healthy lifestyle habits, people can take a small but meaningful step toward lowering their chances of developing type 2 diabetes.
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