Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
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Irritable Bowel Syndrome (IBS) is a common but often overlooked gastrointestinal disorder; as a result, IBS is very prevalent, with less than 15% being diagnosed.
Individuals frequently experience recurrent symptoms such as bloated abdomen, abdominal pain, gas, diarrhea, or constipation, and normalize these symptoms over time or attribute them to "something they ate" or everyday stresses. Therefore, IBS remains undiagnosed for many years.
Why Diagnosis Is Often Delayed
One reason for this delay in being diagnosed is that the symptoms occur intermittently. It is also important to note that the presentation of these symptoms is inconsistent and unpredictable; there may be episodes where the IBS can last many days, and then completely resolve, thus providing a false sense of relief. Therefore, many individuals choose to delay consulting with a physician due to their belief that the symptoms they are experiencing are not serious.
Stigma Around Digestive Health
Another contributing factor is that there is still a degree of reluctance or discomfort associated with discussing problems related to the gastrointestinal tract openly; this only further complicates under-reporting statistics.
A ‘Functional’ Disorder Adds to Confusion
Finally, IBS is a functional disorder. Therefore, routine diagnostic testing will not reveal any visible abnormalities. Many patients may assume that the symptoms they are experiencing are not "real" or are not significant enough to warrant seeking medical attention, even though the discomfort they experience can be quite significant and affect their daily lives.
If you continually ignore symptoms of IBS, it will hurt your quality of life, productivity, and mental health. If you have persistent discomfort, you are likely to develop anxious feelings about eating, socializing, and travelling. Furthermore, if you don't manage your symptoms, you may experience a combination of untreated IBS with one or more other illnesses that are either gastrointestinal or metabolic; consequently, establishing the correct diagnosis for your IBS will be increasingly difficult as time goes on.
It is of the utmost importance to identify and respond to early warning signs of IBS as quickly as possible. A thorough evaluation can rule out other illnesses and provide a pathway for appropriate management, including dietary modifications, stress management techniques, and, if necessary, medical treatment.
Once you address your IBS, you will experience better control of your symptoms and eliminate the long-term consequences of IBS, both physically and psychologically.
Colorectal Cancer is not only one of the most common and deadly cancers, but is also one of the most preventable ones.
Unlike many other cancers, patients have a clear window of opportunity to stop it before it even begins. Almost always, these cancers start as small growths called polyps or precancerous lesions on the inner lining of the colon or rectum.
There is a long interval of time before polyps develop into cancer. During this time, they can be removed if they are identified. If a doctor removes a precancerous polyp during a routine screening, they would not only have nipped the cancer in the bud, but would have also prevented it from occurring.
However, there is a persistent taboo surrounding discussing bowel movements and other risk factors, and public understanding of its symptoms and crucial screening procedures frequently lags.
Dr Jeremy Clark, a consultant general surgeon specializing in colorectal diseases at Nuffield Health in Brighton, has underscored five critical warning signs the public must recognize, The Independent reported.
1. Blood in stool
“Passing blood when you go to the toilet is a worrying feature that you should flag to your GP,” Clark said, adding that the color can vary from bright red to almost black.
“If you see blood in the stools, particularly darker-colored blood or blood that’s actually mixed in with the stools, just once, and it’s significant, that should be reported to your doctor straight away. Don’t wait for that to keep on happening,” he added.
2. Changes in Bowel Habits
Dr. Clark stated that although more constipation may not be a risk factor, any sudden changes in bowel movements that last for a couple of weeks and do not go back to normal must be checked.
“If your bowels go from working once a day like clockwork, and then suddenly you’re going two or three times a day, and the bowels are a bit looser, that’s something that needs to be looked into,” the expert added.
3. Abdominal pain
Dr Clark highlighted that bowel cancers can cause abdominal pain, even in the initial days.
4. Bloatedness
The feeling of being 'quite often’ bloated may also indicate that something is going wrong in the bowel, Dr. Clark said.
5. Unexplained weight loss
Bowel cancers can impact digestion and cause weight loss

Dr Clark said that as these symptoms are common with other conditions, such as hemorrhoids or irritable bowel syndrome (IBS), people often ignore or easily dismiss these symptoms. He urged patients not to ignore and visit their doctor if they notice any of these symptoms.
Also read: US Health Secretary Robert F. Kennedy Jr. Stalls 600M Global Vaccine Aid For Poor Nations: Report
What Is Colorectal Cancer?
The American Cancer Society notes that colorectal cancer is a cancer that starts in the colon or the rectum. Colorectal cancer impacts around 1.9 million people every year, noted the World Health Organization (WHO) as per its 2022 data.
It is a disease of the large bowel and a type of cancer that originates from the rectum or colon. A person's colon, cecum, rectum, and anus make up the large intestine.
According to experts, if you are above 45 years of age or have high-risk factors, you need to take the initiative to be screened.
The FIT (Fecal Immunochemical Test) is a simple, non-invasive at-home stool test kit that can collect a small sample of your feces, which can then be tested.
“If it comes back as positive, that means there is blood in your stools which needs to be investigated,” Clark said, adding that the next step is typically the Colonoscopy – the gold standard.
CBT is a structured way to deal with crises and respond with greater awareness. (Photo credit: AI generated)
Cognitive Behavioural Therapy (CBT) is often mentioned in conversations around mental health, yet its depth and practical relevance are not always fully understood. Rooted in the connection between thoughts, emotions, and behaviours, CBT offers a structured way to recognise patterns, question unhelpful narratives, and respond with greater awareness. Rather than offering quick fixes, it equips individuals with tools that can be applied in everyday situations, making it both accessible and effective. Here’s a closer look at what truly defines CBT and how it works in real life. Aanandita Vaghani, Founder and Mental Health Counsellor at UnFix, listed the five key things everyone must know before considering CBT.
At its core, CBT is not about eliminating difficult thoughts or emotions but about changing your relationship with them. It invites you to step out of autopilot, question familiar patterns, and respond with greater awareness and intention. When approached thoughtfully, often alongside other therapeutic tools, it becomes less about fixing yourself and more about understanding yourself. And in that understanding lies the ability to navigate life with more clarity, flexibility, and choice.
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