Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
Credit: iStock
A stroke can be a life-changing event, not just for the patients but also for their family. As a complex neurological condition, it can affect a person’s physical abilities, communication and everyday independence, often bringing unforeseen challenges for both the patient and their loved ones.
While a stoke is often associated with paralysis, facial weakness or difficulty walking, its impact can extend far beyond body mobility. Depending on which part of the brain is affected, a stroke can change something as fundamental as the way a person eats, speaks, swallows or even breathes.
These changes can be frightening for both the patient and family. Someone who was eating normally may suddenly cough while drinking water. A person who spoke fluently may struggle to find words or produce clear speech. In more severe cases, problems with swallowing can allow food or liquid to enter the airway, creating the risk of serious respiratory complications.
Understanding these changes is an important part of stroke recovery because they are not simply inconveniences, but functions that can directly affect nutrition, communication, safety and independence.
Eating involves a surprisingly complex sequence of movements. The brain must coordinate the muscles of the face, tongue, throat and oesophagus to move food safely from the mouth into the stomach.
A stroke can disrupt this coordination, resulting in dysphagia, or difficulty swallowing. A person may cough or choke while eating, take much longer to finish a meal, have a wet or gurgly voice after drinking, or feel that food is getting stuck.
This is common after stroke. A 2024 systematic review and meta-analysis found that post-stroke dysphagia affected approximately 46.6% of patients overall.
What may look like a simple difficulty with eating can have serious consequences. If food or liquid enters the airway instead of the oesophagus, it can lead to aspiration and potentially pneumonia. In an Indian meta-analysis, dysphagia was reported in approximately 47.7% of stroke patients, while pneumonia occurred in around 20.4%.
This is why swallowing should be assessed after a stroke rather than assuming that a patient can safely eat and drink as before.
Speech and language are different functions, and a stroke can affect either or both.
Some people develop aphasia, where they may know what they want to say but struggle to find the right words, understand language, read or write. Others may develop dysarthria, where the language itself may be intact but weakness or poor coordination of the speech muscles comprised of larynx, tongue, and vocal tract, make their speech incoherent.
For families, this can sometimes be misunderstood as confusion or lack of understanding. A person may appear unable to respond when they may understand everything but be unable to express themselves.
Patience becomes essential. Giving the person time to respond, speaking clearly, avoiding finishing their sentences and using gestures or writing when needed can make communication less frustrating.
Speech and language rehabilitation can also play an important role in recovery.
Breathing is something we rarely think about until it becomes difficult. Yet the brain plays an important role in regulating breathing, while the muscles of the throat and chest help maintain a clear and protected airway.
A stroke can interfere with this system, particularly when it affects areas involved in swallowing, airway protection or respiratory control. Difficulty managing saliva, weak coughing and aspiration can all increase the risk of respiratory complications.
Importantly, breathing problems after stroke do not always present as obvious breathlessness. Repeated coughing during meals, changes in voice after swallowing, excessive secretions or recurrent chest infections may sometimes indicate that material is entering the airway.
Recognising these signs early can help doctors and rehabilitation teams intervene before complications become more serious.
Stroke rehabilitation is often associated with physiotherapy and learning to walk again. While mobility is extremely important, recovery needs to look at the person as a whole.
A patient may regain strength but still struggle to eat safely or communicate effectively. This is why stroke care can involve neurologists, physiotherapists, speech and language therapists, dietitians, occupational therapists and other rehabilitation professionals, depending on the patient's needs.
Swallowing assessments, speech therapy, dietary modifications and targeted rehabilitation can help patients gradually regain function and confidence.
Families are often the first to notice subtle changes after a stroke. Coughing during meals, prolonged eating times, a change in voice after drinking, unclear speech, difficulty finding words or repeated chest infections should not simply be dismissed as part of ageing or weakness after stroke.
These signs deserve medical attention.
Recovery from stroke is not always a straight line. Some functions may improve quickly, while others require months of rehabilitation and continued support. What matters is recognising the problem early and addressing it appropriately.
A stroke does not only affect how a person moves. It can change how they communicate, eat, swallow and protect their airway functions that are central to independence and quality of life.
For families, understanding these changes can replace fear with awareness. For patients, timely assessment and rehabilitation can help turn seemingly overwhelming challenges into manageable steps towards recovery.
The goal after a stroke is not simply to help a person walk again. It is to help them eat safely, communicate confidently, breathe comfortably and regain as much independence as possible.
(By Dr. Vaibhav Seth, Consultant - Neurology, Manipal Hospital, Kolkata)
Credit: Times Network
The Times Network India Health Summit 2026 brought together policymakers, clinicians, researchers and healthcare industry leaders to discuss the future of India's healthcare system, with conversations spanning medical innovation, access to treatment, mental health, women's health and preventive care.
The third edition of the Times Network India Health Summit & Awards was held in New Delhi on October 28 under the theme, The Blueprint for a Future-Ready Healthcare Ecosystem: Innovation. Access. Self-Reliance.
From the use of artificial intelligence (AI) in diagnostics to advances in fertility treatment and the need to strengthen public health infrastructure, various sessions explored several aspects of how healthcare delivery could evolve. Here are the key discussions and takeaways from the summit.
Union Minister of State for Health and Family Welfare Anupriya Patel addressed the summit on building a future-ready healthcare ecosystem. With around 500 Ayushman Bharat cards issued, Patel also said that 132.5 million people had received free treatment under the scheme.
She also addressed India's Viksit Bharat 2047 vision, stating that Union health budget increased from around Rs 37,000 crore in 2014 to more than Rs 1.06 lakh crore.
Delhi Health Minister Pankaj Singh answered key questions about the city’s looming air pollution crisis. He said that the government's various pollution-control measures, including electric vehicle (EV) policy can help fight it. He also spoke about the need for long-term solutions.
Union Minister of State (Independent Charge) AYUSH Prataprao Jadhav, Madhya Pradesh Minister of State Narendra Shivaji Patel and Uttarakhand Cabinet Minister Subodh Uniyal, were also scheduled to address different aspects of healthcare policy and delivery.
Padma Bhushan Dr Shiv Kumar Sarin, leading hepatologist, gastroenterologist, and medical educator who also serves as the Senior Professor, Chancellor, and Director of the Institute of Liver and Biliary Sciences (ILBS), recently spoke about the dos and don’ts to maintain a healthy liver at the Times Health Summit 2026.
From ideal breakfast time to late night eating, the expert spoke about common lifestyle mistakes people make that could worsen their liver health.
The session From Tradition to Therapeutics: The New Science of AYUSH was based on the role of traditional medicine in India's healthcare landscape.
Dr Biswaroop Roy Chowdhury, Founder of BRC Clinics Health, and Dr Tanmay Goswami, Founder of Goswal, discussed Ayurveda, its potential applications and questions surrounding its integration with modern medicine.
The speakers spoke about Ayurveda’s scientific research, evidence, AYUSH funding, clinical applications and integration with western medicine. The experts said that Ayurveda sector is valued at approximately $17–18 billion, while China's traditional medicine sector is estimated at around $30 billion, calling for greater investment in the sector.
Mental healthcare was another focus, with Dr Deepak Kumar, Professor and Head of the Department of Psychiatry at the Institute of Human Behaviour and Allied Sciences (IHBAS), discussing The Next Frontier in Indian Psychiatry: Specialization, Geriatric Mental Health, and De-addiction Strategies.
The doctor discussed immediate threat of suicidal thoughts, warning behavioural signs, screen addiction and need for parents to supervise and limit screen use in children.
Women's health was featured prominently at the summit, with the knowledge session Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes.
The session featured Dr Meenu Walia, Chairman of Medical Oncology at Max Healthcare; Vaishali Iyer, Country Head of Communications, Patient Advocacy and CSR at Novartis in India; and Dr Pankaj Goyal, Senior Consultant and Unit Head of Medical Oncology at Rajiv Gandhi Cancer Institute.
The experts focused on the risk of recurrence, the emotional toll of breast cancer treatment, financial and societal hardships, body image issues, intimacy problems and other challenges patients face after leaving the hospital.
The panel The Fertility Revolution: Reimagining Parenthood in Modern India spoke about the evolving field of reproductive medicine and the challenges faced by people seeking fertility treatment.
The speakers included Dr Ranjana Sharma, Senior Consultant in Obstetrics and Gynaecology at Indraprastha Apollo Hospital; Dr Vimal Grover, Senior Director of Obstetrics and Gynaecology at Fortis LaFemme; Dr Hrishikesh Pai, Founder and Managing Director of Bloom IVF India; and Dr Abha Majumdar, Emeritus Consultant in IVF and Human Reproduction at Sir Ganga Ram Hospital.
The session brought attention to fertility preservation, IVF costs, male infertility, stigma women face, and the judgments that come with seeking IVF for starting a family.
The session From Silence to Care: Why India Can No Longer Ignore Menopause focused on menopause and the need to bring greater attention to women's health during midlife.
The session was led by Sanjith Shetty, Founder and CEO of Miror. He spoke about the suicide rates among menopausal women, along with other life challenges like divorces, retirements, and social isolation.
The fireside chat From LifeSpan to HealthSpan: Can Science Help Us Live Longer and Better? explored the science of longevity and the difference between living longer and maintaining good health for more years.
The conversation featured Dr Chirantan Bose and Dr Preetesh Bhandari, founders of Vytalyou. They spoke about the importance of maintaining muscle health, monitoring neurological health, and warding off lifestyle diseases like obesity and diabetes.
The role of technology in modern medicine was explored in Precision Diagnostics: AI, Genomics & The New Era Of Personalized Care. The panel featured Dr Arjun Dang, CEO and Partner at Dr Dangs Lab; Dr Manish Vaish, Director and Head of the Institute of Neurosciences at Medanta, Noida; and Dr Belal Bin Asaf, Director of the Institute of Chest Surgery, Chest Onco-Surgery and Lung Transplant at Medanta, Noida.
The discussion focused on the evolving role of artificial intelligence and genomics in diagnostics, personalised treatment and improving diagnostic accuracy.
The future of specialised medical services was examined in The Next Frontier of Advanced Care: Scaling Capacity, Innovation & Clinical Excellence. The session brought together Dr V.S. Chauhan, Chairman and Managing Director of Prakash Hospitals and Institutions, and Prof. Dr Sanjeev Bagai, Chairman of Nephron Clinic.
The discussion centred on expanding advanced healthcare capacity, strengthening clinical excellence and leveraging innovation and technology to improve patient outcomes while making specialised treatment more accessible.
Addressing the challenges of equitable healthcare delivery, Reengineering Public Health Infrastructure: Last-Mile Delivery, Digital Health Equity, and Rural Access brought together Dr Anoop Saraya of the Institute of Liver & Biliary Sciences; Dr Charu Dutt Arora of AmeriHealth Home Healthcare, Asian Institute of Medical Sciences; Dr Gyanendra Kumar of Maulana Azad Institute of Dental Sciences; Girish Krishnamurthy, CEO of Tata Medical & Diagnostics; and Dr Jyoti Wadhwa of Apollo Athenaa Women's Cancer Centres.
The session focused on strengthening public health infrastructure, improving rural and last-mile access, and exploring the role of digital health and healthcare delivery models in bridging gaps in access to medical services.
Credit: Times Network
The journey of a breast cancer patient does not end when their treatment comes to a conclusion. There is always a risk of recurrence, which makes regular follow-ups and adherence to treatment important.
At the Times Network India Health Summit and Awards 2026 in New Delhi, a panel formed by Dr Priya Parmar, Chief Operating Officer, Indian Cancer Society, Delhi, Dr. Jyoti Wadhwa - Principal Lead of Medical and Precision Oncology, Apollo Athena Women’s Cancer Centres, New Delhi and Apollo Hospital, Gurgaon, Dr. Meenu Walia, Chairman Medical Oncology, Max Healthcare, Dr Pankaj Goyal, Sr Consultant and Unit Head, Medical Oncology, RGCI, and Vaishali Iyer, Country Head, Communications, Patient Advocacy and CSR, Novartis in India, discussed the big picture after breast cancer treatment.
During a panel discussion titled “Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes,” experts highlighted the physical, emotional, social and financial challenges that women may continue to face after treatment among many more.
For many women, the period after breast cancer can involve more than medical monitoring. They may face fatigue, menopausal symptoms and changes in body image after undergoing a major physical change, while concerns about intimacy, fertility and relationships can affect emotional and mental well-being.
Dr. Priya Parmar highlighted how losing a breast or hair can affect a woman's sense of identity and femininity. Some survivors also face social stigma related to marriage and fertility, while sexual health and relationship concerns may remain difficult to discuss.
The burden can be greater for women who lack family support or have limited financial resources. These circumstances may affect not only emotional recovery but also their ability to attend follow-up appointments and continue treatment.
The financial strain can become particularly difficult if cancer returns and further investigations or treatment are required.
Dr. Meenu Walia said that treatment for advanced disease can add to the economic burden faced by patients and their families.
Also read: Vanessa Trump Recovers From 'Very Invasive' Breast Cancer, Reveals Early Sign Of The Disease
The risk of breast cancer recurrence is not the same for every patient. It depends on the cancer's stage and subtype, tumour grade, lymph node involvement, response to treatment and whether treatment is timely.
Dr. Jyoti Wadhwa explained that different breast cancer subtypes can follow different recurrence patterns.
Triple-negative breast cancer tends to recur earlier, often within the first two to three years after treatment. Hormone receptor-positive, HER2-negative breast cancer, however, can return even 10 to 20 years later.
She also said that patients who achieve a pathological complete response after treatment given before surgery may have a lower risk of recurrence than those with residual disease.
However, a lower estimated risk does not mean the risk is eliminated. Continued monitoring is important even for patients who have responded well to treatment.
Also read: Beyond the Lump: Overlooked Breast Cancer Symptoms That Can Delay Diagnosis
One concern raised by the experts was that some patients stop taking prescribed oral hormone therapy or miss appointments after their symptoms improve.
“Your first attempt at treatment is always your best attempt,” Dr. Walia said, underlining the importance of appropriate diagnosis and treatment from the outset.
Follow-up care helps doctors monitor a patient's recovery, assess treatment-related effects and make decisions based on individual clinical circumstances. The appropriate schedule and any further treatment depend on the patient's diagnosis, risk profile and medical history.
Experts also cautioned against allowing the possibility of recurrence to dominate a survivor's life. Understanding individual risk should help patients make informed decisions, rather than leave them in constant fear that cancer will return.
The long-term effects of breast cancer also have implications beyond the individual patient. Vaishali Iyer, Country Head of Communications, Patient Advocacy and CSR at Novartis in India, highlighted an estimated 140 million productive hours lost due to breast cancer care, drawing attention to its wider economic impact.
Dr. Wadhwa emphasised the need to address treatment-related concerns, including menopausal symptoms and bone health, which may require attention even after primary cancer treatment has ended.
Dr. Pankaj Goyal, Senior Consultant and Unit Head of Medical Oncology at RGCI, stressed that doctors must build trust with patients and explain recurrence risks without causing unnecessary alarm. Discussions about care should also account for patients' personal circumstances and financial constraints.
The panel discussion, titled “Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes,” took place at the Times Network India Health Summit and Awards 2026.
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