Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

Many people struggle to fall asleep because their minds race with worries about the next day or even old memories. To stop this mental chatter, some try complicated breathing exercises or relaxation hacks. However, a simple neuroscience trick involving temperature might help you drift off instantly.

Neuroscientist Kyle Cox suggests that you can fall asleep in seconds simply by placing something cold on your forehead when you go to bed. He explains that this method has been backed by sleep clinics and can be highly effective.

Sleep Hack That Could Help You Sleep Quicker

Researchers have learned that the temperature right on your forehead controls whether your brain stays active or decides to rest.

When the front part of your brain, called the frontal lobe, gets cooled down by even a little bit, just one degree, it automatically tells your body to start producing the chemicals needed for sleep.

The cold also quickly slows down all that busy mental chatter because the part of your brain that handles thinking (the prefrontal cortex) literally cannot work as hard when it is being cooled down.

A 2018 study published in the Sleep Journal also found similar results through a device that that cooled the forehead temperature as a treatment for insomnia. The device improved things like the time it took to fall asleep compared to the patient's own baseline sleep and the time it took to enter different stages of light and deep sleep (NREM Stages 1 and 2).

The two-night treatment helped patients fall asleep faster according to most PSG measurements and was safe. The researchers recommend more studies to see if this treatment works for the longer-term management of insomnia.

General Tips for Treating Insomnia

If you struggle with sleep, the NHS (National Health Service) says that often the best cure is to change your daily sleep habits. If you stick to a healthier routine, your insomnia usually gets much better over time.

Keep a Schedule

Go to bed and set your alarm to wake up at the exact same time every day, even on weekends. This helps set your body's internal clock.

Wind Down

Start relaxing at least one hour before you plan to sleep. This could mean taking a warm bath, listening to calm music, or reading a physical book.

Optimize Your Room

Make your bedroom a perfect place for sleeping. It should be as dark and quiet as possible. Use heavy curtains, blinds, or even an eye mask and earplugs if needed.

Get Moving

Exercise is great for sleep, but do it regularly during the day, not right before bed.

Be Comfortable

Check that your mattress, pillows, and blankets are supportive and cozy so you can easily relax once you lie down.

Things You Should Avoid For Better Sleep

To sleep better, avoid things that keep you awake. Stop smoking, drinking caffeine or alcohol six hours before bed. Do not eat a large meal or exercise intensely late at night. Avoid screens right before bed, limit daytime naps, and always stick to your regular morning wake-up time.

Researchers have recently found that looking closely at the shape of the main buttock muscle, called the gluteus maximus, gives important clues about a person's health. This muscle shape reflects key changes linked to how we age, our lifestyle choices, and medical problems like diabetes.

This new study, done by a team at the University of Westminster, is unique because, unlike older research that only measured how big the muscle was, the team used advanced 3D mapping to show exactly where and how the muscle shape was changing.

These shifts, either the muscle shrinking (atrophy) or becoming inflamed, are connected to things like being frail, the amount of time someone sits each day, fat storage and diabetes risk.

How Do Muscle Changes Indicate Diabetes Risk?

the research analysed a large dataset, looking at over 61,000 MRI scans taken from the large U.K. Biobank health database.

Along with the MRI images, the dataset also included detailed information on 86 different factors for each person, including their medical history, body measurements, and what kind of lifestyle they led.

By putting all this data together, the team was able to figure out which specific factors were strongly linked to changes in the shape of the buttock muscle over time.

The analysis revealed strong connections between muscle shape and certain health factors:

Fitness

People who were considered fitter, meaning they reported doing more vigorous physical activity and had a stronger hand grip, tended to have a greater gluteus maximus shape. This often means the muscle was larger and more defined.

Aging and Frailty

On the other hand, factors like getting older, being generally frail (weak), and spending many hours sitting were all linked to muscle thinning or shrinkage. This suggests that a lack of use and the natural process of aging reduce the muscle's size and fullness.

How Gender Affects Muscle Responses

A very important discovery was that the gluteal muscles don't change in the same way for men and women, especially when they are dealing with a disease. For example, men who were considered frail showed more shrinkage (thinning) in their gluteus maximus compared to women who were also frail.

When the researchers examined Type 2 diabetes, the difference was even more noticeable: diabetic men showed clear muscle thinning (reduced muscle mass), while diabetic women often showed enlarged muscle mass.

This larger appearance in women is likely due to fat building up within the muscle tissue, rather than the muscle itself growing stronger. These differences strongly suggest that the body's biological response to diseases like Type 2 diabetes may be completely different between men and women.

What Does Your Glute Shape Reveal About Health??

The researchers conclude that the shape of the buttocks, rather than simply its size, is more closely connected to fundamental metabolic changes happening in the body. Because the gluteus maximus is one of the largest muscles in the body, its health plays a crucial role in overall metabolic health.

These findings suggest that tracking gluteal muscle shape could potentially become a new way to monitor metabolic health and disease risk.

The NHS will not be automatically inviting all men above a certain age to check for prostate cancer, unlike the approach for some other cancers. The UK National Screening Committee has suggested that the prostate-specific antigen (PSA) test should only be actively offered to men carrying the BRCA gene mutation, which increases their risk. Still, men can request a PSA test from their GP in certain situations.

Olympic cycling hero Sir Chris Hoy, who has received a terminal diagnosis, is among those campaigning for men with known risk factors to be invited for a PSA test at a certain age, even if they do not have any symptoms.

Prostate Cancer Screening: What Is The PSA Test?

A prostate-specific antigen (PSA) test checks the level of PSA in your blood. PSA is a protein produced by the prostate, a small gland in the male reproductive system located just below the bladder. The prostate produces the fluid part of semen.

The NHS says the test might be suggested if you notice symptoms that could point to prostate cancer, such as:

• urinating more often than usual, feeling a sudden urge to pee, or waking up frequently at night to urinate
• blood in your urine
• difficulty getting or maintaining an erection

However, for most men, urinary symptoms are caused by something other than cancer.

A PSA test is usually carried out at a hospital or GP surgery by a nurse or other healthcare professional. Men are asked to avoid certain activities for 48 hours before the test, as these can temporarily raise PSA levels and affect the result. Activities to avoid include anything that leaves you out of breath, like strenuous exercise.

If a man’s PSA level comes back high, they may be offered a repeat test to see if the levels remain raised. If they do, the GP may refer them to a specialist for further investigations, such as a biopsy or an MRI scan.

Prostate Cancer Screening: Why Is The PSA Screening So Controversial?

PSA levels can rise for many reasons, including minor infections, and around 75% of men with a raised PSA do not have prostate cancer. A high reading can lead to referrals for unnecessary biopsies or MRI scans, or treatment for tumours that might never have caused harm.

The PSA test can also miss aggressive cancers. Research has shown that roughly 15% of men with a normal PSA result may actually have prostate cancer.

Prostate Cancer Screening: Who Can Currently Get The PSA Test?

Routine PSA testing is not offered as standard on the NHS. You might be offered a test if a doctor suspects symptoms that could indicate prostate cancer. Men undergoing treatment for a prostate condition may be offered regular PSA checks to monitor how treatment is progressing.

Men aged 50 and over can request a PSA test from their GP, even without symptoms. Campaigners say many men are unaware that they are at higher risk of prostate cancer and should be actively encouraged to think about having a PSA check.

Prostate Cancer Screening: Who Else Could Get It?

If the UK National Screening Committee’s recommendation is approved by the Government next year, men with the BRCA gene mutation could also be invited for a PSA test. Men who think a family member might have had the BRCA gene mutation can request a genetic test on the NHS to find out.