Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
Poor oral health can also impact speech in the elderly. (Photo credit: AI generated)
Parents are the root of every family and the silent pillars who spend their lives nurturing, protecting, and supporting their children through every stage of life. But as they age, the roles slowly begin to reverse. Ageing often brings with it a range of physical, emotional, and cognitive challenges, including reduced mobility, memory decline, weakened immunity, chronic illnesses, dependency, and loneliness. In many ways, growing older mirrors the vulnerability of infancy, where simple daily activities such as eating, walking, speaking, or maintaining personal hygiene may require support and patience from others in the family.
At this stage of life, caregivers step into the role of protectors, offering the same compassion, reassurance, and care that parents once gave selflessly to their children. It is equally important to acknowledge the unwavering efforts of caregivers who devote themselves to ensuring their ageing parents live with comfort, dignity, and love despite the emotional, physical, and financial challenges.
In an interview with Health and Me, Dr Eliza Pereira, Founder—Florina's Angels (a senior citizen daycare and dementia care centre), Bangalore, explained the consequences of overlooking oral health in the elderly.
India has a massive elderly population, making elder care an important healthcare priority. According to population estimates, the senior citizen population in India is witnessing significant growth. As per Census 2011, the population of senior citizens (people aged 60 years and above) in the country stood at 10.38 crore, while projections estimate this number will rise to 17.32 crore by 2026. These figures highlight the increasing need for accessible and inclusive elder healthcare services. While conversations around ageing often focus on mobility, cardiovascular health problems, or mental wellbeing, oral healthcare remains one of the most overlooked aspects of elderly care.
Age-related conditions such as diabetes, arthritis, dementia, Parkinson’s disease, osteoporosis, and weakened immunity can significantly affect oral health. Many seniors struggle with tooth loss, gum disease, dry mouth caused by medications, difficulty chewing, oral infections, bad breath, and poor-fitting dentures. Reduced dexterity due to arthritis or neurological disorders can make routine brushing and flossing difficult, increasing their dependency on caregivers for basic oral hygiene maintenance. Poor oral health can also impact nutrition, speech, confidence, and overall quality of life, making timely oral care support even more critical for ageing individuals.
Addressing oral care accessibility for ageing parents requires a collective and compassionate approach. Caregivers can play a crucial role by encouraging timely dental check-ups, creating simple oral hygiene routines, ensuring dentures are cleaned properly, monitoring medication-related oral side effects, and helping seniors maintain hydration and a nutritious diet. Using age-friendly and specialised oral care solutions such as swallow-safe and non-foaming toothpastes, fluoride-free and remineralising formulations, therapeutic mouthwashes, and no-rinse oral care wipes for dependent or bedbound individuals can help make daily oral hygiene routines easier, safer, and more comfortable for senior citizens. Additionally, products designed with easy-open caps and clear, user-friendly packaging can further improve accessibility and encourage independent oral care among elderly individuals facing mobility, dexterity, or age-related vision challenges.
At the same time, caregivers themselves need emotional support, awareness, and access to the right healthcare guidance to manage caregiving responsibilities effectively. Families and healthcare systems must work together to create sustainable ecosystems where the entire cycle of caregiving and those being cared for feels supported beyond medical attention.
Credit: The Howard Stern Show/ Youtube
American radio personality Robin Quivers has announced being free of cancer after a 14-year journey battling the deadly disease.
Quivers, 73 — who has co-hosted The Howard Stern Show for over 40 years — first announced in 2012 that she had been diagnosed with stage 3 endometrial cancer.
She immediately underwent surgery, numerous rounds of chemotherapy, and radiation to treat the disease. After four years of remission, it returned in 2016.
Now, nearly 10 years later, Quivers is once again “cancer-free.” The radio personality shared the good news during the radio show, The Independent reported.
“Robin kicked cancer’s ass. They said it couldn’t be done,” Stern, 72, declared, calling it “a miracle.”
He recalled the moment Quivers called him with the news, saying, “I couldn’t believe it. And really, I’ve said this to Robin privately, but I would like to say it on the air. Like this is really a miracle.
“I’m gonna say this because this is really true. I’ve watched the whole thing. She took charge of her health. She started to do all the right things. She never deviated, and she really took it seriously.”
Stern and Quivers, who began their radio careers as newscasters at WIOO in Carlisle, Pennsylvania, have been together since 1981.
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Endometrial cancer begins in the endometrium, the inner lining of the uterus. Most uterine cancers are endometrial cancer. If untreated, it can spread to nearby organs such as the bladder, rectum, or more distant organs through the lymphatic system or bloodstream.
The endometrium is highly sensitive to hormonal changes, particularly the balance between estrogen and progesterone. When the body is exposed to excess estrogen without adequate progesterone, the endometrial lining grows excessively. Over time, this prolonged stimulation leads to abnormal cell changes and increases the risk of developing endometrial cancer or uterine cancer.
Dr Fahad Afzal, Consultant Oncologist at Saifee Hospital, told HealthandMe that obesity, PCOS, diabetes, and metabolic syndrome can contribute to hormonal imbalance and lead to endometrial cancer.
"Obesity is one of the most significant risk factors because excess body fat increases estrogen production. Women who are obese therefore have higher levels of estrogen, which stimulates the uterine lining,” the expert said.
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According to World Health Organization data, its incidence is steadily rising, particularly in urban populations where lifestyle changes are more pronounced.”
Dr Smit Sheth, cancer physician at MOC Cancer Care & Research Centre, Mulund, said, “Hormones play a crucial role in a woman’s reproductive health, but when they fall out of balance, they can also increase the risk of certain cancers, including endometrial cancer".
The good news is that endometrial cancer typically grows slowly and is often detected early through regular gynecological exams.
Warning signs that should never be overlooked include
Simple lifestyle changes, maintaining a healthy weight, regular exercise, a balanced diet, managing chronic conditions like diabetes or hypertension, and timely medical check-ups can significantly reduce risk.
Credit: iStock
For years, moderate alcohol consumption, particularly a daily glass of wine, has been associated with potential health benefits, especially for heart health. However, in recent years, a growing body of research, including warnings from the World Health Organization (WHO) and other health agencies, has highlighted that alcohol poses significant health risks from the very first drink.
A recent expert review published in the Journal of Hepatology reiterated this concern, concluding that there is no universally safe level of alcohol consumption.
After examining recent evidence on alcohol use and health outcomes, researchers from the University of Wisconsin concluded that excessive alcohol consumption is unquestionably harmful and that defining a universally "safe" level of drinking remains unsupported by current scientific evidence.
According to the authors, the health risks associated with alcohol vary considerably from person to person. Factors such as age, sex, genetics, underlying medical conditions, medications, and pregnancy status can all influence how alcohol affects an individual's health.
Also read: 844 Million Adults Worldwide Living With Chronic Kidney Disease: Lancet Study
The researchers also questioned the long-standing belief that moderate drinking provides significant cardiovascular benefits.
They found that recent evidence does not support recommending regular alcohol consumption for health purposes. Instead, the review suggests that any potential benefits must be weighed against known risks, including cancer, liver disease, and other alcohol-related harms.
The review adds to a growing body of evidence linking alcohol consumption to an increased risk of several cancers.
A May 2026 study linked alcohol to 62 disorders, ranging from heart and digestive diseases to mental and neurological conditions and cancers.
The study, published in the journal Addiction, showed that the fully alcohol-attributable conditions are mainly grouped under non-communicable diseases and injuries.
These include:
The data also included psychotic disorders, gastritis, ulcers, pancreatitis, fatty liver disease, pregnancy- and perinatal-related conditions such as fetal alcohol syndrome and fetal alcohol spectrum disorders, as well as external causes and injuries, including alcohol poisoning.
"These conditions are 100 per cent alcohol attributable, meaning these diseases would not even exist in the world without alcohol use," said Jürgen Rehm, senior scientist at the Institute for Mental Health Policy Research in Toronto and part of the study team, according to CNN.
"There are another 30 diseases in which alcohol plays a role, such as breast and other cancers, heart disease, stroke, diabetes, and dementia," Rehm said. "These diseases would exist even without alcohol use, but alcohol use is responsible for a certain proportion of them."
The global burden of alcohol-related health issues is immense. The US National Institutes of Health (NIH) estimated that alcohol-related conditions could cost the United States nearly $1.87 trillion between 2011 and 2050, equivalent to about 1.45 per cent of the country's GDP. The NIH also criticized the lack of clear public messaging, which has allowed myths about alcohol's safety to persist for decades.
In 2023, the World Health Organization reinforced this warning. In a statement published in The Lancet Public Health, it declared that there is no safe level of alcohol consumption that does not affect health.
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