Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

Women can play a major role in preventing as well as eliminating Chagas Disease, a potentially life-threatening neglected tropical disease that affects 8 million people globally and causes 10,000 deaths every year, according to UN agencies.

World Chagas Disease Day is observed every year on April 14 to raise awareness around the disease, and the impact it has on lives.

In a statement, the Pan American Health Organization (PAHO) and the Global Chagas Coalition urged health authorities to make women central to the fight against the disease and to empower them to make early detection, prevention, and care.

“Eliminating Chagas disease as a public health problem requires placing women at the center of diagnosis, treatment, and care strategies,” said Dr. Jarbas Barbosa, PAHO Director.

“Ensuring timely access to quality health services, particularly for women of reproductive age, is essential to prevent new infections and advance toward the elimination of congenital Chagas disease in the Region of the Americas,” he added.

What Is Chagas Disease?

Chagas disease, also known as American trypanosomiasis, is a illness caused by the parasite Trypanosoma cruzi, and is primarily transmitted by triatomine insect vectors.

It gets spread through

• oral transmission,
• blood transfusion,
• mother-to-child.
• through transplants of some organs (such as heart or kidney)
• through laboratory accidents.

If left untreated, one third of infected people—including women and the children they carry—will develop life-altering heart, digestive, and even neurological conditions, and may even become fatal.

Once endemic to 21 countries in Latin America, the disease has now spread globally due to migration. It is now a global health concern with cases found in 44 countries including the US, Canada, Europe, Australia, and Japan.

World Chagas Disease Day 2026: Theme

World Chagas Disease Day was celebrated for the first time in 2020.

The theme this year is “Women at the heart of care, protecting the next generation” and underscores the key role women play in family and community caregiving, as well as their greater interaction with health services, particularly during pregnancy.

Chagas Disease: Role Of Women

According to the World Health Organization (WHO), about 2 million women aged 15-44 years are living with Trypanosoma cruzi infection worldwide.

Congenital transmission or mother-to-child transmission remains a major challenge, occurring in about 3–5 percent of pregnancies. However, it also provides a key opportunity for effective intervention.

The transmission cycle of the disease can be effectively broken by

• Treating infected girls and women before pregnancy
• Strengthening screening in maternal and child health services
• Eaccess to diagnosis and treatment.
• Newborn screening can help diagnose and treat, with a cure rate exceeding 90 percent.
• Increase awareness at community and family levels.
• Avoid foodborne transmission

“On the contrary, it represents a strategic opportunity to strengthen more equitable, accessible, and responsive health systems that recognize and respect women’s needs.”

The BBC Breakfast host Naga Munchetty has opened up about her experience of suffering from a painful womb condition, known as the "evil twin sister of endometriosis".

The 51-year-old Naga Munchetty explained her condition as adenomyosis, which can cause extreme pain at any time. Munchetty added that she has faced the condition even while presenting her show, The Independent reported.

Naga Munchetty said that adenomyosis has caused her severe pain since she was in her teens, and she has “become conditioned to accept” it.

“If you’re curled up on the floor screaming, sweating, flooding, passing out, vomiting, that is debilitating. But you end up normalizing that pain.”

What Is Adenomyosis

Adenomyosis is an extremely painful condition, which affects the womb and causes the uterus to enlarge. Although it affects an estimated one in 10 women, it remains undiagnosed in most women.

It is a lesser-known but significantly debilitating gynecological disorder that is commonly mistaken for endometriosis.

Adenomyosis leads to debilitating symptoms such as

• intense pain
• heavy menstrual bleeding,
• cramps,
• abdominal bloating
• fertility issues.

Differences Between Endometriosis And Adenomyosis

Adenomyosis occurs when endometrial cells—typically restricted to the lining of the uterus—break through the myometrium, the muscular wall of the uterus.

Endometriosis, on the other hand, happens when tissue similar to the lining of the uterus grows outside the uterus. These tissues commonly develop on the ovaries, fallopian tubes, or the pelvic lining.

In contrast, adenomyosis is inside the uterus but produces serious complications. These out-of-place endometrial cells continue to act as they would in a regular menstrual cycle, becoming thick and shedding, which leads to internal bleeding, inflammation, and intense pain.

Adenomyosis: The Condition Without Treatment

Despite going to the doctors several times, Naga Munchetty was not diagnosed until recently, as she was led to believe the pain she was experiencing was “normal”.

No absolute cure for adenomyosis exists except for a hysterectomy, which involves the removal of the uterus. Nevertheless, several treatment options can alleviate symptoms and enhance quality of life. These include:

1. Pain Relief

Ibuprofen and naproxen, over-the-counter pain medications, are usually prescribed to relieve menstrual cramps and pain.

2. Hormonal treatment such as

• Birth control pills
• Hormonal IUD (Intrauterine Device)
• Progesterone therapy

GnRH agonists, such as Lupron, induce temporary menopause by suppressing estrogen production, thereby reducing adenomyosis symptoms. However, these injections can cause severe side effects, including mood swings, hot flashes, and bone density loss, making them unsuitable for long-term use.

4. Surgical Intervention

• Endometrial Ablation: This involves the removal of the uterine lining to manage heavy bleeding, but it is not a permanent solution and is not suitable for women who want to become pregnant.
• Uterine Artery Embolization (UAE): A non-surgical procedure that cuts off the blood supply to the affected areas, reducing the size of the adenomyotic tissue.
• Hysterectomy: The only permanent solution for adenomyosis, a hysterectomy is usually considered as a last option for women who have finished their childbearing years.

Hypertension, or high blood pressure, is caused by excessive salt intake; however, according to scientists, there are more reasons. Experts also blame a brain glitch. A part of the brain that makes us breathe while laughing or coughing could also cause a blood pressure spike, as per researchers from New Zealand and Brazil. This could explain why medication is not enough for controlling BP in some people. According to experts at the University of Auckland, there is a part of the brain that could cause high BP, thereby suggesting that the brain is responsible for hypertension.

Is the brain responsible for high BP?

Experts say that the lateral parafacial region is located in the brainstem. It is the oldest part of the brain and regulates heart rate, digestion, and breathing. Its action causes one to exhale during a cough, laugh, or workout. These actions are driven by abdominal muscles. Researchers also found that this area could connect to the nerves that tighten blood vessels and raise blood pressure. However, it is possible to reverse this action by inactivating this region.

What is hypertension?

Hypertension, or high blood pressure, is a condition wherein blood pushes against the walls of the blood vessels with too much force. Initially, it has no symptoms, but it is a silent killer. Over time, untreated high BP can lead to a stroke or a heart attack. While it is mostly believed to be a consequence of smoking, drinking alcohol, eating salty foods, and not exercising, experts have found other causes as well. As per research by the University of São Paulo in Brazil and the University of Auckland in New Zealand, published in the journal Circulation Research, rat brains had their brain cells in the lateral parafacial region switched off.

How is high BP triggered by the brain?

Researchers in the study successfully reactivated neurons in some rats and found that brain circuits ultimately raised BP. Experts mapped out what happened and compared it with rats that did not have hypertension. In the hypertensive group, lateral parafacial region neurons were helping with breathing but were also raising BP. This suggests that changes in breathing, which involve abdominal muscle contractions, can also trigger high BP. This is why patients with sleep apnoea experience interrupted breathing while sleeping and high blood pressure.

Apart from normal breathing, lateral parafacial region neurons are activated when oxygen levels are low. Experts also checked whether they could trigger the brainstem with medication. They noted that it was tricky because drugs would work on the entire brain and not a specific region. It could be activated by signals from the neck cells near the carotid artery. These can be safely targeted with medication.

How to control persistent high BP?

To control persistent high BP, medication every day is a must. But to intensify the benefits, try the following simple tricks:

1. Reduce salt intake
2. Meditation
3. Quit smoking
4. Lose weight
5. Limit alcohol intake