Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

People across the UK are being urged to follow basic safety steps as concerns grow over so-called “evolving” bacteria. A few decades ago, antibiotics were routinely prescribed for a wide range of illnesses and minor infections.

Today, many GPs are far more cautious about giving them out, largely because of the steady rise in bacteria that no longer respond to treatment. Figures from the UK Health Security Agency show that close to 400 antibiotic-resistant infections are being recorded every week in England.

What Are Antibiotic-Resistant Infections?

According to the World Health Organisation (WHO), antibiotic-resistant infections develop when bacteria change over time and stop responding to the medicines meant to kill them. As a result, infections that were once easy to treat become much harder, and in some cases impossible, to cure. This can lead to serious illness, longer hospital stays, and a higher risk of death.

While antibiotic resistance can occur naturally, the WHO warns that misuse and overuse of antibiotics in both humans and animals greatly speeds up the process. This allows resistant bacteria, often referred to as “superbugs,” to survive, multiply, and spread more easily.

Why Is Antibiotic Resistance Dangerous?

The biggest risk linked to these “superbugs” is that they are much harder to treat because standard antibiotics no longer work against them. Infections caused by resistant bacteria can lead to serious complications, including pneumonia and bloodstream infections, which can be life-threatening if not controlled quickly.

In a post shared on X, the UKHSA said: “Bacteria are evolving against antibiotics, with nearly 400 new resistant infections appearing each week in England.” NHS guidance has also warned that several bacteria have already developed resistance as a result of antibiotic overuse. These include MRSA, Clostridium difficile, and the bacteria linked to multidrug-resistant tuberculosis.

A major concern is that this growing trend could eventually lead to new strains of bacteria that cannot be treated with any existing antibiotics.

How To Reduce The Risk Of Antibiotic-Resistant Infections?

According to UKHSA advice, people can play a role in slowing the spread of resistant bacteria by following a few simple precautions in daily life. These include:

• Returning unused antibiotics to a pharmacy so they can be disposed of safely and do not contribute to resistance in the environment
• Practising safe sex, particularly to reduce the spread of infections such as gonorrhoea, which is becoming harder to treat
• Staying up to date with vaccinations, which can help prevent infections in the first place
• Talking to a healthcare professional before taking antibiotics, as they are not always necessary
• Washing hands thoroughly and staying at home when feeling unwell to avoid spreading infection

Many people rely on over-the-counter medicines, but a pharmacist has recently cautioned against the frequent use of some well-known remedies. Occasional indigestion or heartburn is common, but if these symptoms keep returning, there are important health points to be aware of to avoid creating bigger problems.

A pharmacist who goes by Pharmacist Anum on TikTok has shared a warning for people who regularly turn to these treatments. She explained that using certain medications too often can lead to complications, and said it is crucial for people to understand the risks before depending on them long term.

Health Warning For Taking Indigestion Medicines

This is not the first time she has offered such guidance. Only a few weeks earlier, she highlighted key concerns around taking excessive amounts of paracetamol. In her recent video, Pharmacist Anum said: “If you’re taking over-the-counter medicines without being properly checked, you could actually be doing more harm than good. The first group of medicines I’m talking about are those used for indigestion.

“Think about products like Gaviscon, Rennies, and esomeprazole. These are easy to buy over the counter in the UK and, for most people, they are safe when used for a short time.

“Problems arise when people start depending on them, taking them several times a week or even more often. If that sounds familiar, I would urge you to speak to your GP so they can look into what’s really causing your symptoms. Using these medicines too much can raise the risk of side effects and may also hide symptoms of a more serious issue.” In the same video, she also spoke about the risks linked to overusing common painkillers. She added that there are specific things people should understand about indigestion treatments.

What To Do If You Take Indigestion Medicines

Taking indigestion medicines too often, including antacids and proton pump inhibitors (PPIs), can conceal serious health problems and may lead to notable side effects. These can include kidney-related issues, such as stones or damage, as well as electrolyte imbalances, including low sodium or potassium levels.

Using the recommended dose for a short period is generally safe, but long-term use can interfere with normal digestion and may even lead to dependency. This is why it is important to seek medical advice if symptoms continue, so the underlying cause can be identified.

If you have been using these medications for an extended period, or even for years, it is important to speak with your doctor. A discussion about the risks and benefits can help determine whether there may be another health issue behind your symptoms.

What The NHS Says

According to the NHS website: “Always follow the instructions provided with Gaviscon or the guidance given by your doctor. The dose you need depends on the type of Gaviscon you are using.

“If you experience occasional mild heartburn or indigestion, take Gaviscon only when needed. If heartburn or indigestion is frequent, Gaviscon can be taken up to four times a day.

“The most effective times to take it are after meals and before bedtime, whether or not symptoms are present, as discomfort often worsens during these periods.

“If you have been taking Gaviscon for more than seven days and still feel uncomfortable or in pain, speak to your doctor. If you have used Gaviscon regularly over a long time, consult your doctor before stopping, as stopping suddenly may cause symptoms to return.” Further details are available on the NHS website.

Disclaimer: This article is for general information only and is not a substitute for professional medical advice, diagnosis, or treatment. Always follow the instructions on medication labels and consult a qualified healthcare professional or your GP before starting, stopping, or changing any medication. If symptoms persist, worsen, or recur frequently, seek medical advice promptly.

A major international study has revealed that 99% of heart attacks, strokes, and serious cardiovascular events are linked to just four common health risk factors: high blood pressure, high cholesterol, elevated blood sugar, and tobacco use.

The research drew on data from more than 9 million adults in the United States and South Korea, making it one of the largest studies of its kind. Published in 2025, the findings underscore the vital role of early prevention and lifestyle management in reducing cardiovascular risk, as per NDTV.

Even among younger women under 60, a group generally considered at lower risk, over 95% of heart attacks, strokes, and other major cardiovascular events were connected to at least one of these four factors.

High Blood Pressure Leads The Risk

High blood pressure, or hypertension, stood out as the biggest contributor, affecting more than 93% of people who suffered a heart attack, stroke, or heart failure.

“We believe this study demonstrates very clearly that exposure to one or more of these preventable risk factors before major cardiovascular events is nearly universal,” said senior author Dr. Philip Greenland, professor of cardiology at Northwestern University Feinberg School of Medicine.

He added, “The focus now should be on controlling these modifiable factors rather than chasing other less treatable or non-causal risks.”

How Can High Cholesterol Lead To Diabetes?

High cholesterol can trigger heart attacks by contributing to plaque buildup, or atherosclerosis, along the walls of arteries, as per Mayo Clinic. This buildup narrows the arteries and limits blood flow to the heart. If a plaque ruptures, it can cause a blood clot to form, fully blocking the artery. This prevents oxygen-rich blood from reaching the heart muscle, resulting in tissue damage or death, often in the coronary arteries.

How Does Elevated Sugar Lead To Diabetes?

Consuming too much sugar harms blood vessels, triggers inflammation, and contributes to weight gain, high blood pressure, and poor cholesterol levels. Together, these effects speed up plaque buildup (atherosclerosis) in the arteries, limiting blood flow and sharply increasing the risk of a heart attack.

Excess sugar is converted into fat, raises triglyceride levels, lowers “good” HDL cholesterol, and can lead to insulin resistance, creating a cluster of metabolic problems, known as metabolic syndrome—that directly strain the heart.

Early Detection and Management Are Key

The results highlight the urgent need for regular health checks, early screening, and proactive management of common conditions to prevent life-threatening heart problems.

Greenland and his team also point out that their findings challenge earlier reports suggesting cardiovascular events can occur without risk factors. They argue that previous studies may have missed subtle conditions or overlooked risk factors that were below clinical thresholds.

In a related editorial, Duke University cardiologist Dr. Neha Pagidipati, who was not involved in the study, stresses that addressing these health risks early is critical to preventing severe and potentially fatal cardiovascular outcomes.