Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

End of Article

How Reconstructive Plastic Surgery Transforms Lives After Trauma And Cancer

Updated Jun 28, 2026 | 12:00 PM IST

SummaryOne of the biggest breakthroughs in the field of reconstructive surgery has been in the area of post-cancer treatment. It is particularly helpful for women who have undergone surgery due to breast cancer, and patients who have undergone surgery due to oral, jaw, or facial cancer.
How Reconstructive Plastic Surgery Transforms Lives After Trauma And Cancer

Credit: iStock

When one hears about plastic surgery, he or she usually associates it with beauty operations designed to improve one's appearance.

Reconstructive plastic surgery is a very particular field of medicine that addresses problems with the restoration of patients' form and functions who suffer from trauma, cancer, birth defects, burns, and complicated wounds. For many people, reconstructive surgery is far from beautification. It is all about getting back to an independent life.

Reconstructive Surgery After Trauma and Cancer

Injuries that can occur following accidents on the road, incidents at industries, electric burns, and animal bites often lead to severe destruction to the skin, muscles, tendons, nerves, blood vessels, and bones. In addition, cancers of the breast, head and neck, mouth, skin, and limb regions are often treated with extensive surgical excisions to provide complete clearance from the disease.

Though these operations are necessary to save lives, they might lead to considerable impairment and deformities in the patients. Reconstructive plastic surgery helps solve these problems.

Advanced Techniques in Modern Reconstruction

Today's reconstruction surgery uses sophisticated methods, including microsurgical free tissue transfer, perforator flaps, local and regional flap reconstruction, split-thickness and full-thickness skin grafting, nerve grafting, tendon reconstruction, and vascular anastomosis.

The application of microsurgery, in particular, has greatly improved the possibilities for performing reconstruction surgeries through transferring viable tissue from one region of the body to another with the re-establishment of blood supply from blood vessels of just one to three millimeters in diameter using a surgical microscope.

Restoring Function After Cancer Surgery

One of the biggest breakthroughs in the field of reconstructive surgery has been in the area of post-cancer treatment. Women who have undergone surgery due to breast cancer have the option to undergo either immediate or delayed breast reconstruction surgery through implants or through autologous tissues to help restore their self-image and mental well-being.

Similarly, patients who have undergone surgery due to oral, jaw, or facial cancer can improve their functionality and social standing through microvascular surgery.

Burn Reconstruction and Functional Recovery

The other significant factor to consider is the importance of reconstructive surgery in the treatment of burns. Severe burns typically lead to contracture scars and limited movement of joints.

Excision, skin grafting, flaps, and scar revision surgeries are key in improving function, aesthetics, and reducing disability. Reconstruction of hands following injuries or burns allows people to carry out their daily tasks and work.

Restoring Hope Beyond Surgery

Reconstruction is not limited to the surgical theater but is best done using a multi-disciplinary team comprising plastic surgeons, oncologists, trauma surgeons, physiotherapists, occupational therapists, psychologists, dietitians, and rehabilitators. Rehabilitation, scar management, physiotherapy, and follow-up are just as important after surgery as the surgery itself.

Reconstructive plastic surgery is thus much more than a field of surgery; it is a specialty whose goal is to restore hope. Through a blend of surgical skills and compassion, it gives people an opportunity to transcend the physical and psychological effects of injuries or cancers. For many people, it changes the experience of survival into that of recovery.

End of Article

How To Spot Leptospirosis, Dengue, Malaria During Monsoons? Early Symptoms Not To Neglect

Updated Jun 28, 2026 | 09:00 AM IST

SummaryAs the monsoon is upon us, here is a guide to prevent common diseases and infections like dengue, malaria, and chikungunya that often present flu-like symptoms initially.
How To Spot Leptospirosis, Dengue, Malaria During Monsoons? Early Symptoms Not To Neglect

With the onset of the monsoon, the risk of several water-borne, mosquito-borne, and bacterial infections increases significantly due to stagnant water, flooding, poor sanitation, and contaminated food and water.

Many of these diseases can start with mild symptoms similar to the flu, but if they're diagnosed early, you can get the appropriate medical care in time, avoiding serious complications.

Early Symptoms Of Various Monsoon Diseases

One of the important ways to prevent monsoon infections and diseases is to identify warning signs early, Dr. Amit Saraf, Director, Department of Internal Medicine, Jupiter Hospital, told HealthandMe.

Leptospirosis

Leptospirosis gained attention after its cases surged in Kerala recently. The infection has also been reported in Maharashtra, Gujarat, Tamil Nadu, and Karnataka. The bacterial infection typically spreads via contact with water or soil that has been contaminated by the urine of animals infected with leptospirosis, especially during floods.

Initial signs and symptoms include:

  • High fever
  • Chills
  • Intense muscle pain (especially in calves)
  • Headache
  • Red eyes
  • Nausea
  • Vomiting

“Wearing protective footwear, avoiding wading in floodwaters, and covering any open wounds will help minimize the risk of infection,” Dr Saraf recommended.

Typhoid

  • High fever
  • Headache
  • Weakness
  • Loss of appetite,
  • Abdominal pain
  • Constipation or diarrhea
  • Body aches

Dr. Saraf said: “It can cause serious gastrointestinal issues if not treated. Safe drinking water, good hand hygiene, and freshly cooked food are important preventive measures.”

Cholera

Cholera is a water-borne bacterial disease that commonly occurs during monsoons. It often begins with excessive watery stools, vomiting, leg cramps, and rapid dehydration. Dehydration can quickly become an immediate danger of cholera.

The doctor said: “Prevention includes drinking clean water, eating hygienically prepared food, and practicing proper sanitation and handwashing.”

Dengue

Dengue is one of the most common viral diseases spread by Aedes mosquitoes. Often reported in various Indian states during the monsoon, dengue presents with flu-like symptoms. Dengue usually begins with high fever, severe headache, pain behind the eyes, extreme muscle and joint pain, nausea, skin rash, and fatigue.

Malaria

Malaria, a common monsoon disease, is spread by infected mosquitoes and characterized by the following symptoms:

  • Recurrent fever
  • Shivering or sweats
  • Headache
  • Muscle pain
  • Weakness
  • Nausea
  • Vomiting

Dr Saraf said, “Early diagnosis is important to prevent severe diseases. The best ways of preventing mosquito bites are by using mosquito repellents, mosquito nets, and the elimination of breeding sites.”

Chikungunya

Mosquito-borne viral diseases are reported to be the highest during the rainy season. One of them is Chikungunya. The infection is usually marked by sudden high fever and severe joint pain in the limbs. Other early symptoms may include headache, muscle pain, fatigue, and skin rash.

“The infection is usually not deadly but can cause joint pain for weeks or months. Preventive measures include mosquito control and avoidance of mosquito bites,” the expert advises.

Gastrointestinal Infections

During the monsoon period, gastrointestinal infections are also more common as food and water sources are more likely to get contaminated. Early signs of gut infections may include diarrhea, vomiting, cramps, nausea, bloating, fever, and dehydration.

The majority are due to bacteria, viruses, or parasites. The expert said that the risks can be minimized by maintaining food hygiene, drinking boiled or purified water, washing fruit and vegetables before cooking and consuming, and refraining from eating street foods and drinks.

End of Article

It’s Not Just Pollution: How Indoor Lifestyles Are Quietly Worsening Allergies

Updated Jun 27, 2026 | 05:00 PM IST

SummaryA modern indoor lifestyle could be the reason why your allergies keep resurfacing. From smoke, pet dander, to mold, look out for these invisible indoor irritants that could be quietly worsening your allergies.
It’s Not Just Pollution: How Indoor Lifestyles Are Quietly Worsening Allergies

Credit: AI generated image

Many people associate allergies with outdoor pollution, dust, or seasonal changes. However, doctors are increasingly seeing another factor contributing to allergic reactions: the indoor environment.

Allergies Worsening Even When You Stay Indoors?

Over the last two years, there has been a definite increase in patients coming in with respiratory issues. Many people who develop asthma-like symptoms later in life often ask, “Doctor, we hardly go out. How can we develop these problems?” The answer often lies in the indoor pollutants and allergens that go unnoticed in everyday life.

Most people spend nearly 90% of their time indoors — at home, in offices, malls, cars, and other climate-controlled spaces. While staying indoors may feel safer than being exposed to outdoor pollution, it can sometimes mean longer exposure to allergens trapped inside. These may trigger a runny nose, itchy eyes, cough, sinus congestion, asthma, rashes, or hives.

Many indoor irritants are invisible. Common sources include dust mites, pet dander, fungi, chemical vapours from cleaning products, air fresheners, mosquito repellents, and cooking smoke. Poor ventilation or inadequate air exchange allows these allergens to remain trapped for long periods. In many urban homes, indoor air quality can sometimes be worse than outdoor air.

Primary Indoor Irritants That Trigger Allergies

Smoke is one of the most overlooked indoor triggers. Incense sticks, dhoop, and agarbattis, which are part of daily routines in many homes, generate smoke and fine particulate matter that can irritate the airways. Cooking smoke can also be harmful, especially when food is fried, roasted, or cooked with heavy spices. Mosquito coils are another common source. In short, any form of indoor smoke can affect respiratory health, particularly in people who already have allergies or asthma.

Dust is another major concern. Many households practise dry dusting every day, but this can push dust particles back into the air and worsen symptoms in those with dust allergy or asthma. Wet mopping, wet wiping, or vacuum cleaning are safer alternatives.

Air conditioning is another factor. AC filters that are not cleaned regularly can become clogged with dust, pollen, and fungal spores, which keep circulating indoors. Closed rooms with little fresh air make this worse. If anyone in the family smokes or uses vaping products, these are well-established indoor pollutants that can significantly impact respiratory health.

Modern interiors can add to the problem. Fabric sofas, heavy curtains, carpets, and excess furniture increase the surface area where dust collects, and dust mites thrive. Plug-in mosquito repellents, strong floor cleaners, aerosol sprays, room fresheners, smoking, and vaping indoors are also important for indoor pollutants.

How To Tackle It?

Lifestyle changes after the pandemic have worsened exposure. Work-from-home routines, online classes, longer screen time, and reduced outdoor activity mean people spend more hours in closed spaces with limited fresh air.

Small steps help - open windows when outdoor air quality allows, let sunlight in, wash bed linen and curtains regularly, clean AC filters, avoid dry dusting, check damp areas for mold, reduce incense smoke, mosquito coils, and strong fragrances, and air out stored clothes before use.

Pollution remains a concern, but it is no longer the only culprit. The way we live indoors today is quietly shaping our respiratory and immune health. Recognizing these hidden triggers early can prevent allergies from becoming a long-term lifestyle problem.

By Dr Sameer Bansal, Pulmonology Respiratory Medicine Specialist, Apollo Hospitals, Bangalore

End of Article