Can Damaged Sperm Lead To Pregnancy Complications? Study Highlights Uncommon Issues

Updated Oct 17, 2024 | 02:00 AM IST

SummaryDamaged sperm DNA increases the risk of complications such as preeclampsia and premature birth, even doubling it, according to a new study. These findings could make a difference in the execution of fertility treatments and delivery outcomes.
Can Damaged Sperm Lead To Pregnancy Complications?`

Can Damaged Sperm Lead To Pregnancy Complications?

Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

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Ray J In Hospital With Pneumonia And Heart Pain: How Common Are These Complications?

Updated Jan 8, 2026 | 01:00 PM IST

SummaryRay J has been hospitalized with severe pneumonia after reporting heart pain. Here’s what we know about his condition, past health scare, and why pneumonia can trigger serious heart symptoms. Keep reading for details.
ray j pneumonia

Credits: PEOPLE/Canva

Singer and actor Ray J has reportedly been admitted to a hospital in Las Vegas after experiencing what were described as “heart pains,” according to TMZ. The 44-year-old was hospitalized on January 6, with sources telling the outlet that the episode was connected to a severe case of pneumonia. As of Thursday afternoon local time, Ray J was still receiving medical care, TMZ reported.

According to the report, doctors conducted multiple tests, including chest X-rays and an echocardiogram, an ultrasound that checks how well the heart is functioning. The findings from these tests have not been shared publicly. Neither Ray J nor his representatives have released an official statement addressing his health or confirming his current condition.

Although the initial concern focused on possible heart-related issues, TMZ noted that pneumonia appears to be the primary cause behind his hospitalization. It is still unclear whether Ray J remains admitted or has since been discharged.

Ray J Hospitalised With Pneumonia, Heart Pain

This is not the first time Ray J has dealt with a serious pneumonia-related health scare. In late 2021, he was hospitalized after doctors initially suspected COVID-19 before later confirming pneumonia.

At the time, Ray J described the ordeal as life-threatening. “I thought it was over,” he told TMZ while recovering. “I started praying and knew God is good, so I just kept praying.” He later made a full recovery and was discharged after receiving oxygen support.

Despite reports of his recent hospitalization, Ray J has remained active online. He recently posted on Instagram to promote an upcoming event in Austin, Texas, scheduled for January 18 as part of his birthday celebrations. The post made no reference to any health concerns.

Pneumonia: What Is This Disease?

Pneumonia is an infection of the lungs that causes inflammation in the air sacs, known as alveoli. These air sacs may fill with fluid or pus, making breathing difficult and reducing the amount of oxygen reaching the bloodstream. The illness can be caused by bacteria, viruses, or fungi and often presents with symptoms such as coughing, fever, chills, and shortness of breath.

While pneumonia is usually treatable with medication, it can become severe in certain cases, particularly among older adults, young children, and people with weakened immune systems. Because of these risks, pneumonia remains a leading cause of hospitalization, according to the Cleveland Clinic.

Does Pneumonia Come With Heart Symptoms?

Yes. Pneumonia can trigger heart-related symptoms and complications. According to Healthline, patients may experience a rapid heart rate, chest pain, or increased strain on the heart. In more serious cases, pneumonia can worsen existing heart conditions or lead to complications such as arrhythmias, heart failure, or even heart attacks.

The intense inflammation caused by a lung infection places added stress on the cardiovascular system, making early diagnosis and treatment especially important, particularly for older adults or those with underlying heart disease.

How Common Are Pneumonia And Heart Symptoms?

Pneumonia is a common illness and is frequently linked to heart complications. Research cited by the National Institutes of Health shows that roughly one in four hospitalized adults with pneumonia develop major cardiac issues, including heart attacks, heart failure, or abnormal heart rhythms. These complications significantly increase the risk of death.

Heart disease also raises the likelihood of developing pneumonia, creating a two-way relationship between the two conditions. Inflammation from the infection can put additional pressure on the heart, especially in older patients and those with pre-existing cardiovascular problems.

Is Pneumonia With Heart Symptoms Fatal?

Yes, pneumonia accompanied by heart-related symptoms can be fatal. Cardiac complications are common and greatly increase mortality risk, particularly among older adults and individuals with existing heart conditions such as heart failure. The danger is highest in the period immediately following the infection.

Pneumonia places heavy stress on the heart and can trigger heart attacks, strokes, or a rapid worsening of existing heart disease, underscoring the importance of prompt medical care.

  • Increased Mortality: Heart complications can make pneumonia more severe and raise the risk of death.
  • Triggers Cardiac Events: Infection-related inflammation can lead to heart attacks, strokes, or irregular heart rhythms, even in people without prior heart disease.
  • Exacerbates Existing Conditions: For those with heart failure or cardiovascular disease, pneumonia can cause sudden deterioration, leading to respiratory failure and death.

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Working Out For 10 Minutes May Decrease Your Risk Of Colorectal Cancer, Study Proves

Updated Jan 7, 2026 | 05:38 PM IST

SummaryNewcastle University researchers have discovered that even short bouts of exercise can impact cell gene activity related to metabolism, tumor growth and inflammation which can help control the growth of cancerous cells in the colon or large intestine. Over 70,000 new cases of colorectal cancer occur annually in India, making it the fourth most common cancer in the country.
Working Out For 10 Minutes May Decrease Your Risk Of Colorectal Cancer, Study Proves

Credit: Canva

Performing short and intense exercises that last for about 10 minutes may significantly reduce the risk of colorectal cancer, a British study shows.

Researchers at Newcastle University have found that completing brief workouts increases the concentration of several small molecules in the blood that have previously been linked to reducing inflammation, improving blood vessel function and metabolism.

The findings, which were published in the International Journal of Cancer, also noted that even short bouts of exercise can influence the activity of genes that govern tumor growth and fight against cancer.

Dr Sam Orange, Senior Lecturer in Clinical Exercise Physiology at Newcastle University and lead study author, said of the results, "What’s remarkable is that exercise doesn’t just benefit healthy tissues, it sends powerful signals through the bloodstream that can directly influence thousands of genes in cancer cells.

“It’s an exciting insight because it opens the door to find ways that mimic or augment the biological effects of exercise, potentially improving cancer treatment and, crucially, patient outcomes.

“In the future, these insights could lead to new therapies that imitate the beneficial effects of exercise on how cells repair damaged DNA and use fuel for energy.”

How Does It Work?

The study involved 30 participants, both male and female between the ages of 50–78. All of the participants were overweight or obese (a risk factor of cancer) but otherwise healthy.

Researchers had asked each volunteer to complete a short, intense cycling test that lasted about 10 minutes and collected each of their blood samples which were then meticulously analyzed.

After studying about 249 proteins, the experts found nearly 13 protein had increased in their blood flow after the short exercise including interleukin-6 (IL-6), which helps repair the DNA of damaged cells.

When these exercise-induced proteins were applied to colorectal or bowel cancer cells by the scientists in a lab, they discovered that these new proteins could alter the activity of over 1,300 genes, particularly those who were responsible for DNA repair, energy production and cancer cell growth.

As a result, they concluded that performing even small exercises can activate a set of genes in the body's cells that can support efficient use of oxygen and promote energy metabolism. Additionally, the British researchers also discovered that the cell genes which have been previously associated with rapid cell growth were switched off after working out, suggesting that this might aid in controlling cancerous growths in the body.

What Is Colorectal Cancer?

Colorectal or bowel cancer is a common cancer that forms in the tissues of the colon (large intestine) or rectum, often starting as non-cancerous growths called polyps that turn cancerous over time.

Despite being treatable and preventable, colorectal cancer is currently the second leading cause of cancer-related deaths worldwide. Over 70,000 new cases of colorectal cancer occur annually in India, making it the fourth most common cancer in the country.

Typical symptoms usually include :

  • Blood in or on the stool
  • Changes in bowel habits (diarrhea, constipation, narrower stools)
  • Abdominal discomfort, cramps, gas, or pain
  • Feeling that your bowel doesn't empty completely
  • Weakness, fatigue, or unexplained weight loss
Some of the risk factors include risk factors involve being over the age 50, family history, certain genetic syndromes (like Lynch syndrome), inflammatory bowel diseases, and lifestyle factors (diet high in red meat, alcohol, smoking, inactivity). The most effective way to prevent colorectal cancer is through annual colonoscopies, screening and stool tests.

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Expert Explains: Why Do Allergies And Rashes Increase In Winter? According To Dermatologist

Updated Jan 7, 2026 | 10:00 PM IST

SummaryWinter rashes and allergies increase as cold, dry air strips skin moisture and weakens its barrier. Indoor living raises exposure to dust, mold and pet dander, while hot showers and woolens worsen irritation. Experts say hydration, gentle bathing, moisturizers and avoiding triggers help prevent flare-ups during harsh winter months for seniors.
Expert Explains: Why Do Allergies And Rashes Increase In Winter? According To Dermatologist

Credits: iStock

When temperature drops, so does the moisture even in your skin. This is what leads to a rash or allergies. In fact, with changes in temperature, and winters, our lifestyle changes too, this could also be the reason why we experience a winter rash, or allergies. To understand this better, Health and Me spoke to Dr Navjot Arora, Consultant Dermatologist, Dermaheal Skin and Clinic at Dwarka, Delhi, who explained that allergies and skin rashes tend to increase during winter due to both, environmental factors and changes in skin health. "Cold temperatures and low humidity levels reduce moisture in the air, leading to excessive dryness of the skin. When the skin becomes dry, its natural protective barrier weakens. This makes it more prone to irritation, inflammation, and allergic reactions."

Why Does Winter Weather Increase Chances Of Rashes And Allergies?

The doctor explains that during winter, people tend to stay indoors more, and it also increases their exposure to allergens like dust mites, mold, pet dander, and chemical fumes from heaters and cleaning products. "Limited ventilation and closed spaces allow these allergens to build up, triggering allergic responses and skin rashes, especially in individuals with sensitive skin or pre-existing conditions like eczema."

Cold weather also affects blood circulation to the skin. Reduced blood flow can slow down the skin’s repair process and weaken its defense against irritants and allergens. As a result, chronic skin conditions such as eczema, psoriasis, and contact dermatitis often worsen in winter, leading to itching, redness, flaking, and rashes.

Lifestyle Changes In Winter

Doctor also points out that during winters, our bathing habit changes. Dr Arora says, "Frequent hot showers strip away the skin’s natural oils, increasing dryness and irritation. In addition, wearing heavy woolen or synthetic clothing can cause friction, sweating, and contact allergies, particularly in skin folds, which can further contribute to rashes."

Common Symptoms Of Winter Rashes

  • flushing
  • swelling
  • itching
  • flaking skin
  • sensitivity
  • bumps
  • blisters

If not treated well, or in time, it can develop into more serious health threat, especially if you have a family history of

  • eczema or another type of dermatitis
  • psoriasis
  • rosacea
  • allergies
  • asthma
  • sensitive skin

What Are The Cures To Winter Rashes And Allergies?

The rise in allergies and rashes during winter is largely linked to dry weather, indoor allergen exposure, and skin barrier damage. Maintaining proper skin hydration, avoiding harsh soaps, limiting hot water exposure, and wearing skin-friendly fabrics can help reduce the risk of winter-related allergies and skin rashes.

Moisturizers are usually the first line of care for dry skin because they help trap moisture and prevent further dryness. Apply them multiple times a day, especially after bathing or washing your hands. Thicker options like creams or ointments tend to keep skin hydrated longer than lighter lotions.

Petroleum jelly can also be effective, as it forms a protective barrier that seals in moisture. If you prefer to avoid petroleum-based products, alternatives like Waxelene or Un-Petroleum work in a similar way to reduce moisture loss.

Natural virgin oils, such as coconut oil, may help calm irritated skin and restore hydration. Use them on areas that are not acne-prone, and always do a patch test on a small area for 24 hours before wider application.

Oatmeal-based soaps or oatmeal baths can also help soothe dry, itchy skin. You can buy ready-made oatmeal soaps or add finely ground oats to a warm bath and soak for about 10 minutes.

For itching and inflammation, topical hydrocortisone creams, available over the counter or by prescription, may provide relief. Always follow the instructions on the label or use them as advised by a doctor.

Disclaimer: This is not a substitute for actual prescribed medicine. Please consult a doctor before you purchase any medicine or ointment for your rashes.

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