Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.

In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.

The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.

It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.

Uncommon Complications during Pregnancy

The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.

Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.

Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.

Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.

For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.

Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.

Sonali Bendre, actor, who is known for talking about her cancer journey, inspiring other survivors to talk about it too, has found herself at the center of a heated debate after she spoke how naturopathy and autophagy helped her in her cancer recovery.

Bendre, who was diagnosed with stage 4 metastatic endometrial cancer in 2018, wrote on X that she believes autophagy played a role in her healing journey. Her post quickly drew sharp criticism from several doctors.

Doctors Point Out That Cancer Remission Came Through Medical Treatment

Members of the medical community reminded her that her remission was the result of evidence-based cancer treatments, including chemotherapy, radiation and surgery. Many emphasized that autophagy is not a recognized medical therapy and should not be presented as one.

One post from hepatologist Dr Cyriac Abby Philips on X said, “Your cancer went into remission after chemotherapy, radiation, and surgery at an advanced cancer treatment hospital. Not because of Naturopathy. Not because of autophagy. Because you have the option and privilege to opt for the best treatments from scientific practice to help you.”

Bendre Clarifies Her Stand

Following the criticism, Bendre clarified that she was sharing her personal experience as a survivor, not medical advice. She wrote that her journey included elements she explored with the help of her naturopath, and these practices were only part of her overall healing process. In her words, “I have never claimed to be a doctor, but I am certainly not a quack either. I am a cancer survivor, someone who has lived through the fear, pain, uncertainty, and rebuilding that the disease brings.”

What Autophagy Actually Is

Autophagy is a natural process in which the body breaks down and recycles old or damaged cell components. Cells contain various structures that help them function, and over time some of these structures wear out. Autophagy acts like a clean-up and recycling system. It allows cells to dismantle faulty parts and reuse the useful components to maintain healthy cell function. Anything that cannot be used is removed by the cell.

This process is an important quality control mechanism. If too much cellular waste builds up, it can interfere with normal cell activity. Autophagy helps keep cells efficient and healthy. The scientific understanding of autophagy grew significantly after Japanese biologist Yoshinori Ohsumi won the Nobel Prize in Medicine in 2016 for his work uncovering how it works. While autophagy is essential for survival, it is not considered a medical treatment for diseases.

Can Autophagy Treat Cancer?

Experts explain that autophagy plays a complicated role in cancer. In the early stages, it may help prevent tumor formation by clearing damaged components. However, in established cancers, the same process can allow tumor cells to survive stress and become more resistant to treatments like chemotherapy.

Disclaimer: Please consult a qualified doctor or oncologist before choosing any treatment for cancer. Health and Me does not endorse alternative therapies as substitutes for evidence-based medical care. This article is based on publicly available information. All medical conditions should be evaluated and managed under the guidance of a licensed healthcare professional.

What if you are told that the vape you are using contains bacteria found in poop. You read that right. According to a study conducted by HAYPP along with Microbiologist Reynold Mpofu at BioLabTests, bacteria like staphylococcus and bacillus were found on vape, as well as fecal bacterium, E. coli is found on vape, which is often found in public bathroom.

What Did The Study Find?

More than 100 million people worldwide use e-cigarettes or vapes, and at least 1 in 6 people vape in toilet. Furthermore, vapes are rarely cleaned, and thus become germ hotspots.

The study found that vape mouthpieces are highly contaminated with bacteria. More than 1.5 million colony-forming unites or CFUs were identified on the vape mouthpiece, the maximum amount measurable by the lab, carrying as many as 2,300 times more bacteria than a public toilet, which has 50 CFUs per square inch.

“Laboratory analysis revealed that the mouthpiece is the dirtiest component of the vape. This isn’t surprising given that the human mouth, largely considered to be one of the ‘dirtiest’ parts of the body, harbors approximately 700 species of bacteria, that amounts to billions of individual bacteria,” said Mpofu.

The study was able to identify a range of bacteria, including skin microbes to gut bacteria like E.coli.

Also Read: UK Investigates Impact Of Vaping On Its Young Users

The Species Identified

The study identified these following bacteria on the vape:

• Bacillus: commonly found in dust and the air
• E.coli: indicates possible fecal contamination
• Yeast and mold: can cause respiratory irritation
• Staphylococcus: usually harmless, but could cause infection
• Enterococcus: intestinal bacteria that can persist on surfaces

The study was also able to identify bacteria on the vape body. The lab also observed a rapid microbial growth between just 2 to 3 days of use. These colonies could be seen multiplying thousand of times over.

While many of these are found on human skin or surrounding, some are intestinal bacteria, like aforementioned, E.coli, and Enterococcus, which points towards unwashed hands, explaining the transfer on the surface.

“Much like phones, vapes are frequently handled and placed on a variety of surfaces, allowing germs, oils, and dirt from hands, pockets and various environments to latch on the device. The findings confirmed the presence of bacteria, including E. coli and Enterococcus, on the vape body, likely arising from inadequate hand hygiene or the transfer of microorganisms from bathroom environments or other contaminated surfaces,” said Mpofu.

Read: Why Is My Idea Of Break Is To Have A Smoke?

The Timeline Of Bacteria Development

The first signs of microbes start to appear within the first day of buying a brand new vape, especially around the mouthpiece.

By day three, the vape accumulates more than 2,300 times the microbial load typically found on a toilet seat.

By the seventh day, bacteria like E.coli. and Enterococcus and other fecal indicators are detected on the mouthpiece and vape’s body. Mould and bacteria are also found on levels.

By day 14, despite no new use or cleaning, the vape remains heavily contamination. The contamination does not fade overtime.

Read: These US States Vape The Most

The UK recorded its coldest autumn so far when the temperatures fell as low as -12.6C in Scotland. This was the lowest recorded in November from the last 15 years. The mercury also fell to -7.6C in Wales, -6C in Northern Ireland and -6.7C in England. Cold health alters have been issued in England. The UK Health Security Agency (UKHSA) has issued amber cold-health alerts for North West, North East, and Yorkshire and Humber, while other areas are under yellow alerts.

With this new developments, a Yorkshire dentists has pointed out that cold weather could, in fact, impact one's dental health.

Dr Abdul Dalghous, a dentist at Yorkshite Dental Suite said that chilly weather can trigger changes inside your mouth. Even if you have not notices them before, the change in weather and the temperature drop could negatively impact your dental health.

What Does The Doctor Say?

Sensitivity

The doctor says that there could be sudden sensitivity that one can feel when the weather is cold outside. "If you feel a sharp, almost electric twinge in your teeth when you breathe in icy air, it may be a sign that your enamel is under strain," explains the doctor.

Dr Dalghous explains that sudden cold exposure could make teeth contract quickly, irritating the nerves inside the tooth.

Teeth Ache

The cold weather can slightly weaken your immune system, making you more susceptible to illnesses such as colds. The doctor explains, "It’s very common for sinus pressure to feel like a toothache. This is due to your sinuses swelling and pressing on the roots of your upper teeth, often creating a dull, aching sensation. Many people mistake this for dental pain when the real culprit is winter congestion."

Dry Mouth

Another common experience during winters is having a dry mouth. This happens because cold air tends to be less humid and thus breathing it in through your mouth could lead to a drier mouth than usual. "Saliva acts as your mouth's natural defense system, so, when levels drop, your teeth become more vulnerable to sensitivity, plaque build-up and decay," the doctor notes.

Pain While Drinking Cold Beverages Or Eating Cold Food

Winter weather could further amplify the discomfort that is caused by cold food or drinks. "If a sip or bite of a chilled snack causes pain that lingers, it could point to underlying issues such as enamel erosion, cavities or exposed dentine that are becoming more noticeable in colder weather.”

Small Cracks Could Be More Noticeable

Teeth naturally expand and contract when exposed to temperature shifts, and winter tends to make these changes more intense. Over time, this added stress can lead to tiny hairline cracks in the enamel. You may not spot them, but you might feel rough spots, sudden sensitivity in one area, or small chips you never noticed before.

Dr Abdul adds: “To help ease these changes, we recommend breathing through your nose where possible and avoid biting into cold foods. When it comes to your oral hygiene ensure you’re brushing twice a day using toothpaste designed for sensitivity and flossing. Following these will help your teeth during this cold weather!”