Can Damaged Sperm Lead To Pregnancy Complications?
Pregnancy is usually a time of happiness and hope, but it also brings in the unexpected. While there is much talk placed on the health of the expectant mother, the quality sperm coming from the father could dramatically change the outcome of pregnancy. The latest study suggests the risks of sperm DNA damage, even increasing the risks of complications preeclampsia and birth prematurity.
In a groundbreaking research study conducted by scientists from Lund University in Sweden, scientists discovered that DNA damage in sperm increases the risk almost up to double that of preeclampsia, this is a dangerous condition that may arise during pregnancies characterized by high blood pressure. In addition, DNA anomalies also increase the risk of premature births, and this further entails increased related adverse health outcomes for infants born through such conditions.
The next step would be to find out which group of men respond best to methods to prevent and treat sperm DNA damage, and to test these methods to prevent pregnancy complications," said Dr. Amelie Stenqvist, a lecturer at Lund University. According to this study, a significant message is put forward that paternal health assumes an important role in a successful pregnancy.
It focused its research on men, specifically whose sperm contained high levels of DNA fragmentation. For instance, some 20% to 30% of babies born via in vitro fertilization have fathers whose sperm contains damaged DNA. The DNA fragmentation index, an indicator to assess the percentage of DNA damage in sperm, indicated that when the percentage of sperm with a DFI above 30% was observed, they had almost no chance of resulting in natural conception. Even a DFI greater than 20% showed that the chances of getting pregnant are highly risky as the risk factor for pregnancy complications like preeclampsia is much high.
Uncommon Complications during Pregnancy
The most alarming complication during pregnancy is preeclampsia. It affects approximately 5% to 8% of pregnancies worldwide, which can cause fatal conditions for both the mother and the baby. The new findings now point out that sperm DNA damage may contribute to this condition, especially if it is due to assisted reproductive techniques such as IVF pregnancies. The research found that a DFI above 20% doubled the risk of preeclampsia from a mere 5% to almost 11% per.
Apart from causing preeclampsia, DNA fragmentation in sperm is also known to increase the risk for prematurity. Most premature babies experience respiratory, neurological, and developmental complications. Therefore, some degree of early intervention might be important for prospective parents.
Some of the rarer, though serious complications include placental abruption, which is the separation of the placenta from the uterine wall and intrauterine growth restriction, a condition by which the baby does not grow normally in the womb. These conditions though rare are potentially catastrophic both to the mother and the child. Results from this study may help in establishing the contribution of the father in such pregnancies.
Further study into sperm DNA damage is of urgent interest with regard to its consequences for pregnancy outcomes. According to Professor Aleksander Giwercman of Lund University in the field of Reproductive Medicine, "the analysis of DFI should be introduced as routine test in all fertility clinics.". "It could give answers to couples who are having difficulties with infertility, but our latest result also shows that DFI analysis can be a method to identify high-risk pregnancies, explained Giwercman.
For many, DNA fragmentation in sperm is often treatable. Common causes are oxidative stress, age, smoking, being obese, and infections. Addressing these elements will likely reduce DNA damage in sperm for men, raising the chances for a healthy pregnancy and baby.
Overall, the study importance should take into consideration paternal as well as maternal health towards reaching for a healthy pregnancy. Though DNA fragmentation in the sperm is supposed to increase the risk factors for complications in pregnancies, the advances into novel treatment approaches and tests are likely to alleviate complications in many families. Thus the findings of this study offer optimism and pave a pathway to more holistic fertility treatments in the future.
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A visit to the emergency ward (ER) of a hospital can definitely feel scary, and you want every reason to avoid ending up there as a patient. From broken bones to life-threatening emergencies, it’s a place filled with urgency, uncertainty, and intense emotions. Imagine what doctors and other health workers face every day.
However, while many cases are unavoidable, there are several that can be completely prevented, said doctors, while sharing a few. These include:
However, ignoring symptoms like a persistent stomachache or a nagging cough can allow a condition to worsen over time, eventually leading to an emergency.
“People say, ‘It’s pretty mild. I’m not worried about it,’” Dr. Evelyn Huang, an emergency-room physician with Orlando Health, was quoted as saying to Time.
“Days become weeks, weeks become months, and months can even become years, and by the time they're seeing me, these things have progressed so far that they’re now something dangerous.”
Seeking timely medical advice and not delaying checkups can help prevent complications and avoid unnecessary ER visits, the expert said.
Dr. Cheyenne Falat, assistant medical director of the adult emergency department at University of Maryland Medical Center stated that every time a patient comes ER with a drowning case, he hears the same story.
“I would have been watching them, but I thought the babysitter was watching them. I thought my spouse was watching them. I thought their grandparents were watching them.”
The doctor recommended instead starting swimming lessons as early as possible. She also urged for fences with childproof gates near pools.
People often don’t realize how quickly conditions can turn.
“They think, ‘I won’t be at risk for hypothermia because it's a little warmer during the day,’” said Falat. “Then they sweat,” which can leave their clothing damp and their bodies more vulnerable once temperatures drop.
Heat-related illnesses include mild dehydration to heat exhaustion and, in the most extreme cases, heat stroke, which can be deadly.
Recently, for example, he treated a young woman who came to the ER with neck pain, a hoarse voice, and bruising; she assured Yoo that she had wanted her partner to choke her. “I’m not judging anyone who enjoys this, but it's way more dangerous than people think,” he said.
A harmless party drug -- gamma-hydroxybutyric acid, or GHB -- can also turn life-threatening. It is a clear, odorless substance sometimes called “liquid ecstasy.”
While in small amounts, it can make people feel relaxed or euphoric, but when taken in overdose, it can lead to unconscious and breathing difficulties. “It’s one of the most awful sights,” Yoo said , adding that in severe cases, some patients need to be put on a ventilator to survive.
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In today’s hyper-connected world, access to health information has never been easier. Yet, ironically, the ability to understand and apply that information remains one of the biggest barriers to better health outcomes.
This is where health literacy comes in, not just the ability to read a pamphlet or follow a doctor’s prescription, but the broader skill of accessing, comprehending, and using health information to make informed decisions for oneself, one’s family, and one’s community.
While definitions vary, there is consensus that health literacy is multi-dimensional. It involves confidence, critical thinking, and practical skills, knowing when to seek care, how to evaluate health claims, and how to follow treatment correctly. In essence, health literacy is the foundation of preventive care and treatment adherence, and its absence can be devastating.
The scale of the problem in India is stark: nearly 90 percent of Indians have low health literacy. This gap directly affects patient outcomes, from delayed diagnoses and poor compliance with treatment to preventable complications and higher healthcare costs.
Several factors explain this reality:
Low health literacy doesn’t just harm individuals; it amplifies inequities and strains the entire healthcare ecosystem. It also worsens misinformation, as people turn to social media or word-of-mouth for guidance, often encountering unverified or unsafe advice.
Certain health check ups can help improve the chances of conception. (Photo credit: iStock)
Planning for pregnancy is an important step that requires proper health preparation for both partners. Preconception health screening helps couples understand fertility status and detect any underlying health issues. Doctors recommend that couples undergo certain medical tests before trying to conceive so that any health concerns can be identified and managed early. Here are some of the tests before pregnancy that can help couples identify potential risks early and improve the chances of a healthy pregnancy. Couples should opt for these tests without fail to ensure a smooth pregnancy.
While many people focus on health during pregnancy, preparing for pregnancy is also equally important. By opting for some crucial tests, couples can improve their chances of a smooth pregnancy and reduce the risk of complications.
Dr. Payal Narang, Consultant Obstetrician & Gynaecologist, Motherhood Hospital, Lullanagar, in an interview with Health and Me, listed some of the important health check-ups for men and women that must be considered before pregnancy.
Couples should follow the advice given by the doctor and take these tests for a smooth pregnancy.
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