Bone Health In Older Adults (Credit-Canva)
Strengthening your bones is not something that can happen overnight, it takes years for your body to build strong bones and even then, it is natural for them to lose their dexterity. All you can do is keep your body healthy to make sure it is prepared for any unexpected situations. For years, many older adults have been told to take vitamin D and calcium supplements to keep their bones strong and prevent falls. However, a new report from U.S. Preventive Services Task Force (USPSTF) is changing that advice. This report suggests that for most older people, these supplements don't actually prevent falls or broken bones. This might be surprising news, we must understand why falls happen more often as we age, what vitamin D and calcium do in the body, and most importantly, what you can do to stay safe and prevent fractures.
According to the report, vitamin D supplements don't seem to help prevent falls or broken bones for most people over 60. They also found that these supplements, especially with calcium, might increase the risk of kidney stones. This report doesn't mean people with weak bones (osteoporosis), low vitamin D, or who take vitamin D for other health reasons shouldn't take it. It just means that for most healthy older people, these supplements don't prevent falls and fractures.
There are many reasons why older people are more prone to breaking their bones. Our bones are strongest when we're in our 20s and 30s, and they get weaker as we age so naturally, they can break easily. It can also be harder to move around as we get older, sometimes because of problems like arthritis this can affect how we walk and make us less steady.
There are also different issues like neuropathy, which is a nerve problem that can also make it harder to feel your feet and keep your balance. Eyesight is also a culprit as it can cause you to feel dizzy and fall. Some medicines can also make people feel unsteady, and older people often take more medicines than younger people. Low vitamin D itself can also increase the risk of falls, so keeping vitamin D levels up is still important.
USPSTF recommends a few better ways to protect your bone health and prevent broken bones and falls.
Regular walks strengthen your muscles and bones, which helps you stay steady on your feet. It is as simple as practice makes perfect so the more you walk, the better it is. Walking also improves your balance, making you less likely to fall.
Strength training, like lifting weights or using resistance bands, makes your bones stronger and helps prevent fractures if you do fall. It is like a safety cushion, but you must be careful while doing so because it can lead to injuries if done too much.
Activities like tai chi, Pilates, and yoga can improve your balance and coordination, making you more stable and less prone to falls. These can also help you improve your muscle flexibility and strength that in turn helps your body be stronger.
If you have osteoporosis, talk to your doctor about medications that can help strengthen your bones and lower your risk of fractures. Many medications can also have unsavory side effects like weakened joints, losing muscle strength, etc.
A proper diet goes a long way when it comes to your entire body health. So to keep up with your body’s nutrition and muscle health, eat more protein along with a balanced meal that includes loads of fiber, healthy fats and carbs.
Having poor eyesight can be difficult, not only does it make life difficult without glasses, but it also increases the possibilities of getting into minor accidents like bumping into people and missing objects placed in front of us.
Getting enough sleep is also important because when you are not sleeping, you get disoriented and can ignore even obvious things like the last stair in the staircase. Make sure you get enough sleep to keep you fresh and focused.
There are many things that can cause you to have accidents, even in your home. To avoid such falls, make sure there are no lose ends like crooked floor panels, rugs that are sticking out or protruding furniture that can hurt your knees
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Alzheimer’s disease and dementia are often viewed as diseases of old age, with memory loss considered one of their most recognizable symptoms. However, emerging research increasingly points to factors such as diabetes, blood pressure, hormonal changes and lifestyle during midlife, particularly from the 40s onward, that may influence the risk of cognitive decline later in life.
As ageing populations worldwide face a growing dementia burden, doctors are emphasizing the importance of identifying and addressing these risks in midlife. Alzheimer’s disease is a progressive brain disorder that affects memory, thinking and the ability to manage everyday life.
HealthandMe spoke to doctors about the disproportionate burden of Alzheimer’s among women, the link between diabetes and accelerated brain ageing, and how disease-modifying treatments such as lecanemab are changing the treatment landscape. They also highlighted the importance of early assessment to identify cognitive problems that families may otherwise dismiss as normal ageing.
Type 2 diabetes is an important modifiable factor associated with accelerated brain ageing, making cognitive health an important part of diabetes care.
Dr. V. Mohan, Managing Director, Dr Mohan’s Diabetes Specialities Centre and President, Madras Diabetes Research Foundation, told HealthandMe that every diabetes appointment follows a familiar rhythm: check blood sugar, examine the feet, check the eyes, review the heart and kidneys, and renew the prescription. But the brain, more often than not, receives little attention.
Research suggests that type 2 diabetes is associated with accelerated brain ageing, while vascular damage linked to high blood sugar, blood pressure and cholesterol can affect the brain as well as the heart, kidneys and eyes.
The 2024 Lancet Commission on dementia prevention, intervention and care identified diabetes as one of 14 modifiable risk factors associated with nearly half of dementia cases worldwide.
“The message is simple: just as people routinely check their blood pressure, blood sugar, eyes, feet and kidneys, cognitive health deserves attention too,” he said, while suggesting ABCD for Protecting Brain Health in Diabetes:
A – Aim for HbA1c Control
B – Blood Pressure Control
C – Control Cholesterol
D – Diet Management
Read More: Hormone Replacement Therapy May Lower Dementia Risk In Women, Shows Study
Women carry a disproportionate burden of Alzheimer’s disease. According to Stanford, roughly three women are diagnosed with Alzheimer’s for every two men, while data from the Framingham Heart Study cited by the
Alzheimer’s Association estimated that at age 45, the lifetime risk of developing clinical Alzheimer’s dementia was about 20% for women compared with 10% for men.
Dr. Anmol Singh Rai, Consultant Neurology, Fortis Hospital Jalandhar, pointed out several factors that may contribute to this difference. He noted:
“Managing blood pressure, blood sugar and cholesterol, addressing hearing loss, identifying sleep apnea, staying physically active and addressing depression and social isolation can all form part of a broader approach to brain health,” he told HealthandMe.
More than 55 million people worldwide live with dementia today, with a new case developing every three seconds. This number is projected to rise to 139 million by 2050.
With the arrival of disease-modifying treatments such as Leqembi (lecanemab), the importance of identifying cognitive decline early has become even greater.
"For three decades, Alzheimer's treatment has leaned on drugs that modestly improve cognition, function and behavior, buying patients and caregivers meaningful time. But none of them alter the underlying biology of the disease," Dr. Praveen Gupta, Chairman, Marengo Asia International Institute for Neuro and Spine (MAIINS), Marengo Asia Hospitals, Gurugram, told HealthandMe.
The disease-modifying therapy for Alzheimer’s, Leqembi, was cleared in the US in 2023, followed by Japan the same year, China in June 2024, the European Union in 2025, and India in August 2026.
"Unlike everything that came before it, lecanemab is designed to act on the pathological process itself, not merely its downstream consequences," Dr. Praveen Gupta said.
However, the treatment is not meant for everyone with Alzheimer’s. It is approved for early Alzheimer’s disease, including mild cognitive impairment and mild dementia, rather than moderate or advanced disease.
That makes timely diagnosis particularly important.
"Patient selection now hinges on confirming amyloid pathology, through cerebrospinal fluid analysis or blood-based biomarkers, before treatment even begins," Dr. Praveen Gupta explained.
The experts noted that brain health is not something that needs attention only after memory loss begins.
Midlife is an important window to control blood pressure, blood sugar and cholesterol, remain physically active, address hearing and sleep problems, and pay attention to changes in memory or thinking.
For people already showing cognitive symptoms, early medical assessment can help distinguish normal ageing from mild cognitive impairment, dementia or potentially treatable conditions.
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Cardiac arrest is considered one of the most urgent medical situations. It can occur unpredictably, at home, at work, while traveling, or anywhere. It is characterized by a blockage in the heart's arteries, and it differs from a heart attack, which is a situation when the heart stops pumping blood into the body. After a few minutes, oxygen deficiency happens and affects the brain and other organs. Therefore, it is important to know how to perform cardiopulmonary resuscitation (CPR).
CPR is an emergency lifesaving technique that uses chest compressions and, in some situations, blowing mouth-to-mouth air into the person who has suffered a cardiac arrest, to help maintain blood circulation and oxygen delivery to vital organs when a person's heart has stopped beating effectively. It does not restart the heart by itself, but it can keep blood flowing until an automated external defibrillator (AED) is available or emergency medical professionals arrive.
Importantly, CPR is not a skill limited to doctors or healthcare professionals. It can be administered by ordinary people for whom learning the basic CPR techniques is easy.
If someone faces cardiac arrest, rapid actions may save this person's life. If CPR is performed directly and immediately after a cardiac arrest, it will be possible to keep the flow of blood to the brain and other organs before the arrival of medical experts. The use of CPR can improve the chances of survival for patients who have experienced cardiac arrest.
Besides, in combination with early defibrillation through an AED, it can be even more effective. AED is a portable medical device that checks the heart rhythm of the person experiencing cardiac arrest and delivers an electric shock to restart a normal heartbeat.
However, sometimes people prefer to do nothing for fear of mistakes. But it is much more dangerous not to act at all.
It begins with identifying the presence of a possible cardiac arrest in the patient. The patient will generally fall, become unconscious, and will not breathe properly. They can occasionally breathe abnormally with strange sounds, which should not be considered breathing properly.
If you see anyone fall and become unresponsive, check whether they respond to your questions and breathe normally. Tell any passerby to call the emergency services and bring an AED device, if one is present. If the patient is not breathing normally, initiate CPR on them.
If the patient is an adult, hands-only CPR can be done easily by everyone. For this, you need to keep the heel of one of your hands in the center of the person’s chest, keep your other hand over it, and press down with a rapid rhythm. The compression must be continued at a pace of around 100-120 beats per minute.
Also, you can use the AED device if one is available. Turn on the AED and follow the steps according to the voice prompts from it. The AED device will analyze the rhythm of the heart and give a shock.
Another reason for reluctance to administer CPR is the notion that it should be administered only by doctors, nurses, and other professionals. However, even basic CPR can be taught to regular citizens using special courses. It takes only a couple of hours of practice for someone to gain enough confidence to use CPR in emergencies.
CPR training should be more accessible in schools, offices, and residential communities, as it would help people know what to do in those critical first few minutes.
Cardiac arrest will not wait for doctors to show up. When cardiac arrest occurs, the first person on the scene might be either a relative, co-worker, friend, or a total stranger. Knowing CPR will prepare you for these moments of life or death. A simple skill learned today may help save someone’s life tomorrow.
(Dr. Lalit Kapoor, Senior Consultant - Cardiac Surgery and Robotic Surgery – Narayana RN Tagore Hospital, Mukundapur, Kolkata)
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Worried about your graying hair? It may reflect a natural cellular response to DNA damage, according to a study by Japanese researchers.
Hair color comes from melanocyte stem cells (McSCs), which live inside hair follicles and produce melanin, the pigment responsible for hair and skin color. These cells are especially sensitive to DNA damage from environmental and internal factors.
While DNA damage is linked to both aging and cancer, researchers at the University of Tokyo found that McSCs can take different paths after being damaged — including one that leads to hair graying and another associated with melanoma, a type of skin cancer.
When McSCs suffer certain types of DNA damage, they can undergo a process called senescence-coupled differentiation, or seno-differentiation. The damaged stem cells permanently differentiate and are eventually lost, leading to hair graying.
This response is driven by the p53–p21 pathway and may help eliminate damaged cells before they can become cancerous.
Also read: Unusually High Cancer-Fighting Immune Cells Could Explain Why Some People Live Beyond 100: Study
Published in Nature Cell Biology, the study examined how McSCs respond to different types of DNA damage.
Professor Emi Nishimura and Assistant Professor Yasuaki Mohri used long-term in vivo lineage tracing and gene-expression profiling in mice to study the fate of these stem cells.
The researchers found that DNA double-strand breaks triggered seno-differentiation. In this process, damaged McSCs irreversibly differentiate and are lost, resulting in hair graying.
However, the response was different when the cells were exposed to certain carcinogens, including 7,12-dimethylbenz(a)anthracene, or ultraviolet B. In these situations, McSCs could bypass the protective differentiation process, retain their ability to self-renew and expand clonally.
This process was supported by KIT ligand signals from the surrounding tissue and epidermis, which suppressed seno-differentiation and pushed the cells toward a tumor-prone state.
“These findings reveal that the same stem cell population can follow antagonistic fates—exhaustion or expansion—depending on the type of stress and microenvironmental signals,” Nishimura said.
“It reframes hair graying and melanoma not as unrelated events, but as divergent outcomes of stem cell stress responses,” she added.
Read More: Ferritin Face: Can Pale Skin Signal Iron Deficiency?
Not necessarily. The study does not show that people with gray hair have a lower risk of cancer.
Instead, the findings suggest that hair graying can be the result of a protective cellular response in which damaged stem cells are eliminated. When that response is bypassed, damaged McSCs may persist and contribute to melanoma development.
The researchers say the findings offer a framework for understanding how the same stem-cell population can contribute to either tissue aging or cancer depending on the type of damage and signals from the surrounding environment.
Genetics plays a major role in when hair turns gray. There are also some lifestyle changes that can prevent graying, support hair and overall health. These include:
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