On Monday night, a magnitude 6.6 earthquake struck Japan, leading to a tsunami warning. Fortunately, authorities reported minimal damage, and the warning was soon lifted. According to local media, there was only one minor injury involving a man who fell at his own home.
Japan, located in the Pacific Ring of Fire, experiences approximately 1,500 tremors annually. However, these quakes have a long-lasting impact on one's health—both physical and mental.
1. Wound Infections
Earthquake-related injuries range from cuts and bruises to fractures and crush injuries. If not attended to on time, these wounds can lead to infections like sepsis, tetanus, or even amputations if untreated. Regions with scarce medical resources face higher risks of untreated injuries and antimicrobial resistance. Ensuring prompt medical care and deploying teams to assess building safety is critical to preventing further injuries and fatalities.
A recent study examined infections in 225 earthquake survivors with musculoskeletal injuries treated between February and April 2023. It found that gram-negative bacteria were common in the wounds of the victims. Acinetobacter baumannii (49.4%) and enterococci (28.6%) were the most prevalent. Many pathogens were multidrug-resistant, with 76% from wound cultures and 58% from deep tissue cultures showing resistance. Common infections included surgical site infections (32.8%), urinary tract infections (5.3%), bloodstream infections (5.7%), and pneumonia (0.4%). Intensive care was required for 35.6% of patients, with a mortality rate of 2.7%.
2. Infectious Diseases
Earthquakes disrupt water supplies, leading to unsanitary conditions that spread waterborne diseases such as cholera. Meanwhile, it also pushes people to take shelters in dingy places, which can outbreaks of measles, respiratory illnesses, and parasitic infections like leishmaniasis. Cold conditions and stress suppress immunity, increasing the risk of disease spread.
3. Chronic Conditions
Access to medication and medical care is often disrupted by earthquakes. Studies show increased rates of heart attacks, strokes, and diabetes following earthquakes due to stress and disrupted routines. Destruction of health records and facilities exacerbates these issues, especially in disaster-prone regions.
4. Healthcare Disruption
Damaged medical facilities and transport links hinder healthcare delivery. Pregnant women and individuals with chronic diseases face heightened risks. Refugees and displaced populations encounter accessibility barriers to healthcare services.
5. Psychological Trauma
Survivors of these earthquakes often suffer from anxiety, depression, and Post Traumatic Stress Disorder (PTSD). Tailored mental health programs are crucial for recovery, especially for those already living in conflict zones or displacement.
On April 14 2010, a 7.1-magnitude earthquake struck Qinghai Province, China, devastating Yushu County. A psychological relief study, published in the Journal Of Affective Disorders in 2011, assessed the mental health of 505 survivors three to four months post-disaster. Using tools like the PTSD Checklist-Civilian version (PCL-C) and Hopkins Symptoms Checklist-25 (HSCL-25), the study found prevalence rates of 33.7% for probable PTSD, 43.8% for anxiety, and 38.6% for depression, with one-fifth of participants experiencing all three. Key risk factors included being female, experiencing intense fear during the quake, and having limited social support, as measured by the Perceived Social Support Scale (PSSS).
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A small lump in the neck is easy to overlook. In many cases, such swellings are linked to minor infections and settle on their own. But not every neck lump is harmless. The neck houses numerous vital structures, including lymph nodes, glands, blood vessels, and nerves, all within a compact area.
As a result, a seemingly minor swelling can sometimes be an early sign of an underlying condition that requires timely medical attention.
The neck houses important organs and tissues, including the thyroid gland, lymph nodes, salivary glands, major blood vessels, and nerves.
This area can be deceptive for two reasons:
Adding to the challenge, many serious neck conditions, including certain cancers may not cause pain in their early stages.
It’s been observed that the majority of neck swellings are benign.
Common non-cancerous causes include:
Reactive lymph nodes: Often develop after a cold, sore throat, dental problem, or skin infection. They are usually tender and tend to resolve within a few weeks.
Thyroid nodules: Quite common in adults and often harmless. These lumps typically move when swallowing.
Cysts: Such as branchial cleft cysts or sebaceous cysts, which are generally smooth, rounded, and slow-growing.
Lipomas: Soft fatty growths that can move easily beneath the skin.
Tubercular lymph node enlargement: Still frequently seen in India, presenting as gradually enlarging, usually painless neck nodes.
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While many neck lumps are harmless, certain features warrant a consultation with a doctor within one to two weeks:
Associated symptoms such as unexplained weight loss, mouth ulcer, persistent fever, night sweats, hoarseness, difficulty swallowing, chronic cough, or unexplained ear pain
Individuals with a history of tobacco use, alcohol consumption, previous radiation exposure, HPV-related disease, or a family history of thyroid cancer or lymphoma should be especially vigilant.
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Early diagnosis is key to ensuring the most effective treatment.
Evaluation typically begins with a detailed clinical examination, as the location of the lump often provides important clues.
Common investigations include:
When cancer is detected early, treatment is often less extensive and outcomes are significantly better.
Several common mistakes contribute to delayed diagnosis:
Seeking expert assessment early can prevent complications and improve treatment options.
A quick self-examination can help identify changes early.
A neck lump is often nothing more than a temporary response to infection or inflammation. However, some conditions, including cancers of the thyroid, lymph nodes, and head and neck region can present as painless swellings long before other symptoms appear.
The key is not to panic, but not to ignore it either. When it comes to neck swellings, early evaluation can make the difference between a straightforward treatment and a much more complex journey later on.
By Dr Akshay Kudpaje, HOD/Senior Consultant - Head & Neck Oncology at HCG Cancer Hospital, Hebbal, North Bangalore
Credit: AI
For decades, melasma treatment began and ended with a tube of cream. The typical first treatment for those stubborn brown-grey patches on the forehead, upper lip and cheeks that are typically caused by sun exposure, hormones or pregnancy was once hydroquinone, retinoid and steroid combinations.
Patients would put some cream on for months, and get some improvement, and then when they stopped, the pigmentation would reappear. Today, these creams have still got a role but dermatology has come a long way and now, patients have so much more to work with, acting on the melasma from different angles at the same time.
There are more choices available within the realm of creams. Gentler brightening agents like thiamidol and 2-MNG have been developed to do the same job as hydroquinone, but they do it in a different way in the body.
Initial studies indicate that these ingredients can be as effective as older favourites, irritating less than older ingredients that are already doing their job of irritating sensitive skin prone to developing melasma in the first place.
Another compound, malassezin, has shown promising early results in that it has been found to inhibit the process of pigment production itself. Due to the chronic and relapsing nature of melasma, dermatologists are more inclined to use these less aggressive, but more tolerated long term maintenance treatments as opposed to short term treatments alone.
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The most obvious change in how the skin is treated for melasma is the way of lasers and light-based treatments. A side advantage of the low-fluence picosecond lasers is that they break up excess pigment with very short, gentle energy pulses, meaning that there's less skin damage as a side effect, which is a drawback of older, more aggressive laser settings.
Fractional lasers are now also employed in conjunction with topical treatments to enhance drug delivery into the skin, essentially combining the two treatments. They are regarded as non-invasive technologies since they do not involve any incisions or extended downtime and most patients are able to return to their pre surgery routine within a day or two.
Chemical Peels are also available in a re-optimized formulation for the skin that tends to melasma. Newer types of combination peels use lesser amounts of various active ingredients and less of a single strong acid, reducing the chances for additional pigmentation, which is a common worry in dark skin tones.
They are now more frequently prescribed with topicals and lasers as part of a multi-pronged approach, rather than as a treatment on their own, as they are done in a series of milder sessions.
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The technology of microneedling has also come a long way. This once again basic but now formulated with serums and even exosome-based formulations is an area that calms inflammation and helps to regulate the pigments of the skin as it recovers.
This "angle" is called "regenerative" because newer treatments aren't just intended to lighten or fade existing skin melanin, but seek to address the skin's environment that is causing melasma to reappear.
Non-invasive is more than just procedures performed in the clinic. In recent years, low doses of tranexamic acid taken orally under medical supervision has been added to the melasma tool box.
It is internally active, in that it slows blood flow in the blood vessels, which is now known to help trigger the production of pigment in the skin, and is therefore a valuable addition to the treatment of melasma, particularly when other topical treatments are not effective.
There's one thing that sets the tone for the ever-changing landscape of melasma treatment: there's no single answer. It is now known that melasma is a real multi-faceted skin problem that is influenced by multiple factors such as genetics, hormones, sun exposure, heat and inflammation.
Many dermatologists prefer to use a multi-layered approach to skin care for treatment, such as a topical therapy, an in-office procedure and, if applicable, oral skin care therapy, depending on the skin type and pigmentation of the patient. That's not only for quicker results, it also helps to reduce the likelihood of the skin darkening more after treatment, which is more common in patients with darker skin tones.
Today, instead of a one-and-done, dermatologists are more apt to craft a gradual approach that involves calming active pigmentation, then moving to a maintenance regimen that is lighter to avoid pigment re-flash.
“As it is a multi-factorial disease, using any one modality is always going to be limited and a multi-modal approach that combines topical, procedural and sometimes systemic treatment, is what is helping us achieve more lasting results and reduced relapse rates,” says Dr. Ajay Rana.
Despite such innovation, one thing is true: sun protection is a must. If they're going to hold up, it's going to be because of the broad-spectrum sunscreen and the consistent application of it, along with physical protection such as sun hats.
If not, the most sophisticated of the procedures will eventually be replaced by renewed pigmentation.
Although it's a challenging condition to treat, melasma is not a quick fix. However, today there are more ways for patients to visibly improve, and even more of them are not invasive, and have less side effects than five years ago.
If you've used a cream before and stopped using it, it might be worth talking to a dermatologist again; the treatment options are quite different now.
Credit: AI
Fatty liver and liver damage are not identical. While fatty liver refers to a buildup of excess fat inside the liver cells, liver damage describes harm caused to the liver due to inflammation, scarring, toxins, infections, or any long-term disease.
The liver turns fatty, when the body stores too much fat in the liver. This can be caused due to obesity, insulin resistance, type 2 diabetes, high cholesterol- referred to as MASLD (Metabolic dysfunction associated Liver Disease). High consumption of alcohol or chronic hepatitis infection can also lead to fatty liver.
In many cases, fatty liver causes no obvious symptoms, especially in the early stages. Some people may feel tired or notice discomfort in the upper right side of the abdomen, but many often know about it incidentally- either during blood tests or through an ultrasound scan.
Liver damage, on the other hand, can range from mild irritation to severe and permanent injury. The damage may be caused by viral hepatitis, alcohol misuse, certain types of medicines, autoimmune diseases, inherited conditions, or fatty liver that has turned serious.
Liver damage may be referred to inflammation, liver-cell injury, fibrosis, cirrhosis, or a reduction in the function of the liver. In short, fatty liver is one condition, while liver damage points to a wider range of liver diseases.
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The relationship between the two is important. Fatty liver does not always mean that the liver is badly damaged. Certain people have a simple fatty liver, where fat is present but there are little or no inflammation or scarring in the liver. This stage often improve with weight loss, a healthy diet, exercise, and a reduction in alcohol intake, if alcohol is a factor. However, in some people, fatty liver can progress.
When this fat buildup causes liver swelling and cell damage, it is called MASH (Metabolic Dysfunction-Associated Steatohepatitis) which can lead to an injury and the formation of scar tissue in the liver. Over a period of time, this can progress to fibrosis and, in advanced cases, cirrhosis. At this stage, the liver is damaged and may not be in a position to function properly.
Symptoms also differ. Early fatty liver is often silent. More serious liver damage may cause jaundice, swelling in the legs or abdomen, easy bruising, severe fatigue, confusion, itching, or dark urine. These symptoms suggest the liver is under undue stress and needs proper medical management.
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Doctors diagnose these conditions by taking note of the medical history, getting blood tests done, scans, and sometimes specialized tests or even a liver biopsy. Blood tests will show any signs of liver inflammation or liver dysfunction, whereas scans will reveal the presence of fat or scars on the liver.
The key message is this: fatty liver is not always severe liver damage, but it can damage the liver if left ignored. The earlier it is diagnosed, the better is the chance of stopping or reversing the problem. Healthy weight management, regular exercise, balanced nutrition, control of diabetes and cholesterol, and abstinence of alcohol are the important protective steps.
If someone has ongoing fatigue, yellowing of the skin, abdominal swelling, or abnormal liver tests, they consult a doctor at the earliest. Early attention can make a major difference in protecting long-term liver health.
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