Are You At Risk For Early Stroke? Your Blood Type Could Hold The Answer

The blood group you belong to is more than just a marker to match your donation; it may have something telling you about your probability of acquiring certain diseases. A new study published in the Journal of Neurology notes that it can be made an assumption from your blood group by which you are most likely to have an early-onset ischemic stroke at the age under 60.

Although the factors like genetics, age, and lifestyle are the factors that best contribute to the risk of a stroke, this new research has really shed new light on how blood group can be considered as playing a pivotal role than ever thought.

A study suggests that an independent relationship exists between blood type A and an elevated risk for an early-onset ischemic stroke. Ischemic strokes are the presence of a blood clot in one artery, which causes blockage of blood flow to the brain, and about 90% of all stroke cases. The CDC suggests that in the United States, someone has a stroke every 40 seconds while one person dies from a stroke every 3.5 minutes.

This new research, hence, opens the possibilities that an earlier incidence of ischemic stroke in youth could be attributed to blood type A.

But it's worth remembering that blood type is just one of hundreds of risk factors, according to co-author Braxton Mitchell, PhD, MPH, a genetic epidemiologist at the University of Maryland School of Medicine. "In the grand scheme of things, it's a much smaller risk factor than others," he said. Other genetic, environmental, and lifestyle factors still determine stroke risk.

Study authors conducted a genome-wide association analysis, recruiting nearly 17,000 patients with stroke aged 18 to 59 years from 48 studies and more than 599,000 controls who never had a stroke history. The analysis was aimed at exploring genetic variants throughout the human genome in greater detail.

The ABO blood group possessed genetic differences, and the blood type A was the strongest risk factor for a stroke that occurred early in life. The possibility of having an early onset ischemic stroke was 18% higher among people with blood type A compared to the rest of the blood groups. Such a high risk could be associated with a higher susceptibility to blood coagulation, which is one of the most common causes of ischemic strokes.

On the other hand, individuals with type O blood have a 12% reduced risk of an early-onset stroke compared to other blood types. This is in-line with earlier research that has found people with type O blood are more likely to be at low risk for blood clotting inside their arteries, which could be the reason why their overall risk of having a stroke decreased.

Another blood group-the research looked at blood group B-for which a weak association is found with the onset of early and late stroke. However, the authors indicate that when sex and other risk factors are adjusted, no association between blood group B and increased stroke risk exists. In persons with blood group AB, there is no significant association discovered for having an elevated stroke risk.

While this study points to the effect of blood type, it is important to understand that blood type alone is not a strong predictor of stroke risk. Many other factors are comprised in this, including lifestyle, and most importantly, underlying health conditions. Age is one critical factor. According to the CDC, your risk for stroke doubles with each decade after age 55.

While strokes are more likely to affect people who are 65 years of age and older, one in seven strokes strikes people aged 15 to 49.

Thirdly, gender another factor that has been related to increased risks of stroke conditions. The female population is more prone to stroke compared to the male population and tends to have a worse outcome in terms of disability and death due to stroke.

It was recently indicated in the 2022 study that young women aged between 35-45 years had a 44% increased risk of ischemic stroke as compared to men aged between 35-45 years. Perhaps pregnancy or the use of birth control could be some of the factors behind the usual increased risk in women.

While the study does show a genetic element linked to blood type and stroke, other controllable factors are more important risks for stroke. Here are some steps you can take to reduce your total risk:

1. Control Blood Pressure: High blood pressure forms one of the most dominant risks for strokes. Control through regular monitoring, medication if required, and lifestyle modifications can prove to reduce this significantly.

2. Maintain a Healthy Weight: Being overweight increases the risk of stroke. Anyone can benefit from staying at a healthy weight and living a healthy lifestyle. A balanced diet and regular exercise can help you achieve and maintain a healthy weight and thus minimize your risk for stroke.

3. Reduce Alcohol Intake and Quit Smoking: Too much alcohol drinking and smoking are also significant risk factors for stroke. Cutting down on alcohol consumption and quitting smoking would be two very important lifestyle changes for anyone interested in being healthy.

4. Stay Physically Fit: Exercise is known to keep the heart healthy, reduce blood pressure, and promote a healthy weight all of which contribute to a decrease chance for stroke.

5. Monitor Your Cholesterol: It's a fact that high cholesterol builds up plaques in arteries, thereby increasing the chances of stroke occurrence. Fruits, vegetables, whole grains, and lean proteins are part of a heart-healthy diet that helps keep cholesterol at bay.

This research thus brings forward a new and enlightened perspective of the correlation between blood type and stroke risk, especially in younger ages. Although type A blood might have a propensity for developing early ischemic stroke, it is worth noting that this is just one of many factors responsible for developing a stroke.

Focusing on controllable lifestyle factors such as remaining within a healthy weight range, staying active, and managing blood pressure will help significantly reduce the chances of having a stroke regardless of the blood type.