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A recent study published in the BMJ journal Heart highlighted an important correlation between extreme weight fluctuation and increased mortality risk in obese individuals with cardiovascular diseases. The research is conducted by Angila Ruskin University (ARU), and analyzed data from 8,297 UK participants recruited through the UK Biobank study. The participants of the study were tracked over 14 years. This study was thus marked as one of the most extensive investigations into weight change and mortality risk among cardiovascular patients.
The study was led by Dr Jufen Zhang with Prof Barbara Pierscionek and Dr. Rudolph Schutte. They studied the long-term effects of weight fluctuations on health outcomes. The research was also able to find that both weight gain and weight loss of more than 10kg, or 22lb can significantly increase the risk of death in obese individuals with cardiovascular disease.
Participants who gained more than 10kg over the study period experienced a three-fold increase in cardiovascular-related deaths.
Their all-cause mortality risk nearly doubled compared to those who maintained a stable weight.
Those who lost more than 10kg faced a 54% higher risk of all-cause mortality.
This suggests that both weight gain and weight loss can have detrimental effects on patients with pre-existing cardiovascular conditions.
Dr. Zhang noted: "It was perhaps unsurprising that significant weight gain was associated with higher mortality, but interesting that a similar association was found among those who lost a lot of weight."
The traditional view for a healthy life is to lose that extra weight, however, this study shows that even when you lose extra weight drastically, which is a trend being promoted by the fitness industry, it can raise your risk of cardiovascular diseases. The findings thus challenge the common perception that any weight loss in obese individuals is beneficial. What the research points out is the importance of maintaining a stable weight, even within the obese range, which is crucial for reducing mortality risk.
Metabolic Instability: Large weight fluctuations can disrupt metabolism, leading to hormonal imbalances and stress on vital organs.
Muscle Loss: Rapid weight loss, particularly when not managed properly, can result in the loss of lean muscle mass, which is essential for heart health.
Underlying Health Issues: In some cases, unintentional weight loss can indicate the presence of undiagnosed health conditions.
The study was also able to pinpoint specific lifestyle and demographic factors that could lead to weight gain. These include a higher BMI, smoking and previous alcohol consumption. They have been associated with an increased likelihood of major weight gain. Another factor is that younger individuals were more prone to significant weight gain as compared to older participants.
The study comes at a critical time as obesity rates in the UK continue to rise. According to the Health Survey for England:
Your skin is often considered a reflection of your body's inner wellbeing, when it comes to kidney function, the connection goes beyond what may initially be something on the surface. The kidneys are responsible for filtering out wastes and toxins in the blood, balancing electrolytes, and helping to control moisture levels. Once kidney function breaks down, its effects are felt not only overall but also are reflected in discernible skin-related changes—dryness, pigmentation, long-term itching, and even hives.
But when the kidneys are unwell, they do not just impair internal function but also manifest themselves on the outside, and specifically on the skin. In the opinion of Dr. Sreedhar Reddy, Urologist and Urology Surgeon, "Kidney-related ailments frequently cause palpable changes to the skin, which may act as preliminary signals for renal illness."
When the kidneys do not effectively remove waste products and excess water from the body, toxins in the blood buildup. This accumulation manifests as several dermatological manifestations indicating intrinsic renal disease. These are:
Xerosis (Severe Dryness of the Skin): Patients can have very dry, rough, scaly skin, which is usually accompanied by cracking. Dr. Reddy describes, "Extremely dry skin that is tight and tends to crack is frequently seen in patients with end-stage kidney disease who are on dialysis or need a transplant."
Pruritus (Itchy Skin): Itching is one of the most common symptoms of kidney disease. A recent survey of individuals on hemodialysis found that 61% reported experiencing at least a moderate level of itching, with 25% describing it as "very" or "extremely intense." This persistent itch occurs as waste products accumulate in the blood, irritating nerve endings.
Pigment Disorders and Rashes: Inability of the kidneys to function properly can cause the accumulation of metabolic byproducts in the skin, causing color changes and rashes. "Dome-shaped, intensely itchy rashes tend to mean that the kidneys are not clearing toxins well," adds Dr. Reddy.
Aside from skin disorders, kidney disease has an effect on a person's overall appearance because of metabolic disturbances and fluid imbalance.
Weight Changes: Kidney disease may result in sudden weight loss from muscle atrophy or sudden weight gain from fluid buildup. "Patients tend to develop swelling of the face, hands, and feet because of too much fluid," explains Dr. Reddy.
Changes in Skin Texture and Color: Kidney impairment can result in pallor, yellowish or grayish complexion, and a dull skin.
Hair and Nail Changes: Thin hair, ridges, and brittle nails are reported by many patients with chronic kidney disease (CKD).
Some other health disorders linked with kidney disease can cause skin conditions and changes in appearance:
Diabetes and Hypertension: Diabetes and hypertension are major causes of kidney disease, and both diseases can worsen skin conditions like itching and delayed healing of wounds.
Liver Dysfunction: A dysfunctional liver, usually associated with kidney problems, can cause bile salts to pile up beneath the skin, which may cause intense itching.
Blood Diseases and Autoimmune Disorders: Certain cancers, thyroid disease, and autoimmune disorders such as celiac disease may also lead to long-term itching secondary to systemic inflammation and nerve stimulation.
For those of us who care about our skin and our well-being, ensuring that our kidneys are functioning properly is important. Dr. Reddy stresses that making some small lifestyle adjustments can greatly enhance kidney health and stave off overt skin decline.
Reducing the intake of sodium, phosphorus, and potassium while increasing antioxidant-rich foods can protect kidney function and enhance skin health.
Adequate water intake helps flush out toxins, reducing the burden on the kidneys and preventing dryness and irritation in the skin.
Physical activity improves circulation, enhances waste elimination, and supports overall metabolic function.
Tobacco and alcohol also add to kidney stress, resulting in fluid buildup and inflammation that may adversely affect the skin.
Routine tests of blood pressure, blood sugar levels, and kidney function may help identify early evidence of kidney disease, averting severe complications.
Early warning signs of kidney disease can be identified and avoided in order to prevent severe complications. If you suddenly notice unexplained itching, a chronic rash, extreme dryness, swelling, or a great weight gain, seek advice from a health expert. Kidney function can be tested by conducting blood tests that eliminate other health conditions like diabetes, anemia, or thyroid disorders.
Your kidneys are also responsible for detoxification, the balance of fluid, and metabolism. When compromised, the effects are not only internal but also evident on your complexion and overall look. By living healthy, keeping an eye on kidney function, and consulting a doctor when needed, one can have healthy kidneys along with maintaining healthy skin's natural sparkle and radiance. Dr. Reddy affirms, "Healthy kidneys mean healthy skin. Paying attention to both can improve overall well-being and quality of life."
Dr. Sreedhar Reddy is a MBBS, MS(Gen sur), DNB (Urology), MNAMS (urology), FRTS, FIMS at Apollo Hospital, Bangalore in India
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Boils that form in or around the ear can be painful and irritating, and knowing how to handle them is key to preventing complications. Experts warn that you should never try to pick, pop, puncture, or cut open an ear boil, as doing so may spread the bacterial infection and lead to further issues, including more boils.
If you notice a bump in or around your ear, it's likely to be either a pimple or a boil. While both can be uncomfortable and cosmetically unpleasant, boils require special care. Understanding how to recognize, treat, and prevent them is essential for ear health.
A boil typically presents as a painful, red, and hard lump on the skin. These tend to appear in areas with hair and sweat—yes, that includes your ear canal, which has fine hairs that, along with earwax, help trap dirt and debris.
Because it’s hard to see inside your ear, it may be difficult to distinguish a boil from a pimple. However, a boil will generally grow larger than a pea and become soft or "fluctuant," meaning it contains fluid inside. If you or someone else can safely examine the bump, look for signs like swelling, pinkish-red skin, and a white or yellow centre. Boils in the ear may also cause pain in the ear, jaw, or head, and might even affect hearing if they block the ear canal.
In some cases, ear boils will heal without medical intervention. To help them drain naturally, keep the area clean, apply warm compresses several times a day, and avoid touching or squeezing the boil. If using a compress inside the ear, ensure it’s made from clean medical cloth and isn’t overly wet, as excess moisture could cause a swimmer's ear.
Boils form due to bacterial infections, usually from Staphylococcus aureus, that develop in hair follicles. The infection results in a buildup of pus and dead tissue, which forms a visible bump. They’re more common in areas with hair and frequent sweating, like the armpits, face, neck, inner thighs, and buttocks. To prevent ear boils, gently clean your ears during showers and avoid harsh or invasive cleaning tools.
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If the boil doesn’t resolve on its own within two weeks, it’s time to seek medical care. A doctor may need to perform a minor surgical procedure to drain the pus by making a small incision. Antibiotics may also be prescribed to clear the infection.
You should seek professional treatment if:
- The boil keeps coming back
- It persists beyond two weeks
- You develop a fever or nausea
- The pain becomes severe
Avoid using tweezers, fingers, cotton swabs, or any tools to try and examine or remove the boil yourself, as the ear canal is highly sensitive and prone to further infection from scratches or irritation.
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Colour blindness, or colour vision deficiency, is a condition where a person has difficulty perceiving colours accurately. While often associated with adults, colour blindness can also affect children—sometimes without them even realising it. Experts emphasise the importance of early detection, especially since colour blindness is inherited and is far more common among boys than girls. Because children may not be aware that they see colours differently, recognising the signs early can play a key role in helping them adapt and thrive both academically and socially.
Also known as colour vision deficiency, this condition is most often inherited and typically passed down through genes on the X chromosome. However, it is not always something you're born with—it can also develop later in life due to certain eye or brain injuries, specific medical conditions, or even as a side effect of some medications.
Children with this condition often show difficulty in identifying or distinguishing colours. This often becomes evident during preschool or early school years when children begin learning about colours. They may confuse red with green or blue with yellow and may repeatedly mislabel colours even after correction.
Abnormal patterns of colouring during activities like drawing or painting may also suggest colour blindness. For example, a child might colour the sky pink instead of blue or use orange for leaves. While occasional mistakes are normal, consistent errors could point to an underlying issue in colour perception.
Another significant identifier is the trouble engaging with colour-based study materials. Many classroom exercises rely heavily on colours—such as sorting games, charts, and even instructions using coloured markers. A colour blind child might struggle with these tasks, which can lead to frustration and difficulty keeping up with peers.
While there is no cause for this condition, there are several strategies and equipment that can help children manage the condition effectively. Specially designed glasses and contact lenses may improve colour perception in some types of colour blindness. Additionally, digital tools and mobile apps can assist by recognising colours and offering alternative cues.
Educational adaptations can also make a difference. Parents and teachers can support learning by using patterns, symbols, or labels along with colour-coded materials. Maintaining proper lighting can further enhance contrast and make colour identification easier.
Experts also recommend teaching children to rely on alternative strategies for identifying colours—such as using brightness levels or object positions rather than hue. These coping mechanisms can boost their confidence and reduce confusion in everyday activities.
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