Timothy had always been health-conscious. After years of social drinking, she decided to quit alcohol for good. But giving up the ritual of sipping on a drink at social gatherings felt impossible. That's when alcohol-free beer and wine seemed like the perfect alternative—offering the taste and experience without the intoxication. However, what Sarah didn't realize was that these supposedly "harmless" drinks might still be affecting her liver in ways she hadn't anticipated.

With a global shift toward healthier choices, the rise of alcohol-free beverages has been fuelled. Do these drinks, however, live up to their promise of being risk-free? New research shows that while they may eliminate the dangers of intoxication, they still pose metabolic and liver-related risks, which calls for moderation in the long run.

What Happens in your Body within 10 Minutes of Drinking Alcohol-Free Beverages?

The first time you take a sip of an alcohol-free beverage, your body responds almost instantly. Anshul Singh, Lead Clinical Nutritionist and Dietetics Department says, "In as little as 10 minutes, your taste buds have picked up on the flavors, and your brain might even get a placebo effect, giving you the sensation that you're about to be drunk. Some alcohol-free drinks have up to 0.5% ABV, which goes into the bloodstream in minute quantities but will probably not affect you in any significant way."

By the 30-minute mark, your body has metabolized the sugars, artificial sweeteners, or additives in the drink. "Some people may experience a mild insulin spike, which can cause temporary energy boosts. Some non-alcoholic drinks also contain fermentation byproducts or botanical extracts that mimic the sedative effects of alcohol, causing slight drowsiness or relaxation," adds Anshul.

After 60 minutes, most of the drink has been metabolized. Although there is no risk of intoxication, repeated consumption can subtly affect metabolism, gut health, and even trigger cravings for alcohol among those in recovery. Those sensitive to sugar, caffeine, or preservatives might experience even more pronounced effects over time.

How Alcohol-Free Drinks Affect Your Gut and Liver Connection

Your liver and gut health are connected, forming what is called the gut-liver axis. Anshul emphasises, "Even though drinks without alcohol seem harmless, they usually contain sugars, artificial sweeteners, and fermentation byproducts that can disturb this delicate balance."

• High sugar content may lead to insulin resistance, inflammation, and fat accumulation in the liver.
• Artificial sweeteners may change the gut microbiota, causing metabolic imbalances.
• Preservatives and artificial flavors can also enhance gut permeability, thus potentially leading to leaky gut syndrome.

Long-term consumption of these drinks may gradually affect digestion, liver detoxification, and overall metabolic health, making moderation necessary.

Do Alcohol-Free Drinks Still Trigger Liver Enzymes?

Even though these nonalcoholic beverages contain virtually insignificant alcohol, the liver processes them as well. "These small concentrations of alcohol-which may go as high as 0.5% ABV-trigger the liver's detoxification pathways but only at much weaker intensities compared to ordinary alcoholic drinks. But the added sugars, artificial sweeteners, and preservatives in the products could pose significant pressure on liver functions over the long term," explains Anshul.

High sugar intake causes insulin resistance, which can lead to the buildup of fat in the liver and increase the risk of developing NAFLD. Some fermentation byproducts in these beverages also trigger oxidative stress, which puts extra pressure on the liver. Though occasional consumption will not pose a significant threat, regular consumption might lead to chronic liver stress and metabolic imbalance.

Do Non-Alcoholic Beverages Affect Liver Detoxification?

Although trace amounts of alcohol exist in alcohol-free beer and wine, the body will still have to metabolize them. The body employs the same enzymatic pathways used for alcoholic beverages but at a much lower intensity. However, the added sugars, preservatives, and fermentation byproducts present their own set of challenges:

• Mild inflammation to the liver due to the additives and byproducts within the drinks.
• Insulin resistance resulting from excessive sugar intake, causing fat accumulation in the liver.
• Detoxification pathways are overburdened, and impairment of liver function occurs gradually.

Alcohol-free drinks do not cause the liver to become overwhelmed as traditional alcohol does, although it does have a lower, but still important, risk for someone who is drinking too much. For someone with a problem of liver disease or metabolic syndrome, limiting alcohol-free drinks is also important.

Should You Drink Alcohol-Free Beverages?

Alcoholic beverages have always been a dangerous drink, but the safer option for those who want to avoid intoxication. However, it is not totally risk-free. Its impact on metabolism, gut health, and liver function cannot be ignored. Although they are not harmful at first, their consumption over a long period leads to insulin resistance, liver stress, and imbalance in the gut.

For the consumers who love these drinks, moderation is the way forward. The expert shares, "The choice of brands with the least additives, lower sugar, and natural ingredients will reduce risks. In addition, supplementing with a diet that is rich in antioxidants, fiber, and hydration can complement the liver in general."

For most, thought that adopting alcohol-free beverages was a healthier decision. On discovering their side effects on liver health, though, she learned to limit its intake and settle for alternatives that included infused sparkling water, herbal teas, or even kombucha with controlled sugar levels.

The bottom line? Alcohol-free doesn't mean consequence-free. The best way to achieve long-term health is by paying attention to what goes into the body and yet still enjoy social rituals of preference.

Anshul Singh is the Team Lead with the Clinical Nutrition and Dietetics Department at Artemis Hospitals in India.

Former US Senator Ben Sasse is battling Stage 4 pancreatic cancer that has spread around his body. According to his doctors, he now has four types of cancer: lymphoma, vascular, lung cancer, liver cancer, and pancreatic cancer.

Speaking to The New York Times’s “Interesting Times” podcast, the Republican Senator from Nebraska reflected on his life and impending death.

Sasse was diagnosed with Stage 4 pancreatic cancer in December 2025, which remained in the shadows for a long time. Until late October, Sasse had no symptoms. But it started with a lot of back and abdominal pain. Initially, he thought it was due to “some ab muscles pulled from stupid forms of training”.

His doctors thought Sasse had some undiagnosed celiac disease or some dairy allergy. However, a full body scan in December revealed that Sasse’s “torso is chock-full of tumors.”

“In mid-December, I got a three- to four-month life expectancy,” he was quoted as saying.

“They told me over the course of the next couple of days that I already have five forms of cancer: lymphoma, vascular, lung cancer, bad liver cancer, and pancreatic, where it originated,” the former senator added. “So, it was pretty clear that we’re dealing with a short number of months left to live.”

Sasse represented Nebraska in the Senate for eight years before resigning to become the president of the University of Florida in July 2024.

During the interview, Sasse said his condition has improved since last December -- his pain is 80 percent reduced.

"I’m at Day 99 or something since then, and I’m doing a heck of a lot better than I was doing at Christmas," he said.

However, the former senator noted that he deals with nausea, as well as bleeding on his face due to intake of the investigational new drug daraxonrasib.

During the interview, the former lawmaker’s face was covered in dried blood.

Death A Wicked Thief, Says Ben Sasse

Sasse, a father of three, said he felt a “heaviness” with respect to realizing he did not have much time left with his family.

“I didn’t like the idea of my 14-year-old son not having a dad around at 16,” he remarked. “I didn’t like the idea of my daughters, who are 22 and 24, not having their dad there to walk them down the aisle. I felt a real heaviness about that.”

However, the Nebraska Republican said he has “continued to feel peace about the fact that death is something that we should hate.”

“We should call it a wicked thief,” he continued. “And yet, it’s pretty good that you pass through the veil of tears one time and then there will be no more tears, there will be no more cancer.”

What Is Pancreatic Cancer? Know The Warning Signs

Pancreatic cancer has long been one of the toughest challenges in oncology. With a five-year survival rate hovering around 13 percent and recurrence rates approaching 80 percent after treatment, the odds have historically been stacked against patients.

The prevention and early detection remain vital.

Experts warn that pancreatic cancer often masquerades as common ailments, delaying diagnosis. Here are some early symptoms that should never be ignored:

• Abdominal or back pain that worsens over time or eases when leaning forward.
• Unexplained weight loss without changes in diet or exercise.
• Jaundice, including yellowing of the eyes and skin, sometimes with intense itching.
• Changes to urine or stool, such as dark urine or pale, greasy stools.
• New-onset diabetes without obvious risk factors.
• Persistent fatigue unrelated to poor sleep or lifestyle

Three simple lifestyle changes, such as regular physical activity, cutting down sedentary time, and improving sleep duration, may significantly boost your brain's cognitive abilities and reduce the risk of dementia later in life, according to a new study.

Dementia is a neurodegenerative condition affecting an estimated 55 million people globally. It is characterized by a decline in memory, thinking, and social abilities.

Together, the three simple lifestyle changes cut down the risk of late-onset dementia by 25 percent.

Published in the open-access journal PLOS One, the systematic review and meta-analysis of over 69 prospective cohort studies involving millions of cognitively healthy adults aged 35 and above showed the potential benefits of lifestyle behaviors such as regular physical activity, cutting down sedentary time, and improving sleep duration.

According to the Alzheimer’s Association, a person’s overall risk for developing Alzheimer’s disease—the most common form of dementia—is about 11 percent. However, the study found that with the simple suggested lifestyle changes, the average person’s risk decreases to approximately 8 percent.

The study emphasized that people do not need elaborate and expensive longevity hacks to stay mentally sharp as they age.

The reduction is “fairly comparable to the effect sizes sometimes seen with medications for chronic diseases,” said Akinkunle Oye-Somefun, a researcher at York University in Toronto, who led the study, NBC News reported.

Sitting For Long Periods Worst For Your Brain

The findings showed that avoiding sitting for longer periods had the greatest effect and can have a long-term benefit for the brain.

Sitting for more than eight hours a day increased dementia risk by almost 30 percent, at the same time being regularly active, even just going for a walk every day, decreased dementia risk by an average of 25 percent.

Long sitting hours can also spike a person’s risk of other conditions such as cardiovascular disease, diabetes, and obesity, all of which in turn raise dementia risk.

Getting between seven and eight hours of sleep each night also had a greater benefit on the brain.

Also read: 'Game Of Thrones' Actor Michael Patrick Dies After Battle With Motor Neurone Disease

The risk of dementia increased by 18 percent among those who slept less than seven hours, while sleeping more than eight hours per night also raised the risk of the neurodegenerative disease by 28 percent.

Importantly, moderate physical activity “offsets dementia risks even when other risk factors are present,” said Oye-Somefun, NBC News reported.

However, “many people assume that being physically active cancels out the harm of sitting for long periods. It doesn’t,” Oye-Somefun said. “We shouldn’t do one of these things alone; we should do them all.”

Also read: Simple Brain Training Exercise Cuts Dementia Risk For 20 Years, Study Finds

What Is Dementia?

Dementia is an umbrella term used to describe a significant decline in mental function that is serious enough to affect everyday life. It commonly impacts memory, thinking, and reasoning skills.

Dementia itself is not a single disease but a collection of symptoms caused by underlying conditions such as Alzheimer’s disease or vascular dementia.

Common signs include

• memory problems,
• confusion,
• difficulty finding words,
• changes in mood or behavior,
• trouble completing familiar tasks.

These symptoms usually worsen over time and are not considered a normal part of ageing. Although there is no cure, treatment options can help manage symptoms, and early diagnosis plays an important role in care planning.

It was during the COVID-19 pandemic that Annabelle Gurwitch, an American author, actress, and television host, developed a "a little persistent cough".

Suspecting it to be a COVID symptom, Annabelle went for a check-up. Her doctor alarmingly informed her about something suspicious on her lungs. Soon after, an X-ray and a biopsy confirmed her diagnosis of stage 4 cancer.

But, here's the catch. Annabelle is a non-smoker. She also lived a healthy lifestyle and exercised every day, and felt like she was in really good health, besides the persistent little cough.

Also read:American Author Annabelle Gurwitch Writes New Memoir On Stage-4 Lung Cancer Diagnosis

HealthandMe spoke to health experts to understand how a persistent cough signals the risk of lung cancer.

If you, too, are a non-smoker who is leading a healthy lifestyle and has no medical conditions other than a persistent cough, then you must visit your doctor right away, advised the experts.

"A persistent cough can be an early warning sign of lung cancer, especially when it shows specific features rather than behaving like a routine respiratory illness," Dr Sameer Khatri, Principal Director - Medical Oncology, Max Super Speciality Hospital, Patparganj, told HealthandMe.

The doctor noted that the cough becomes suspicious when it persists beyond three weeks without a clear cause or fails to respond to standard symptomatic treatment such as cough syrups, bronchodilators, etc.

"A change in a pre-existing smoker’s cough—for example, becoming more frequent, severe, or different in character—is particularly important. In non-smokers, a new, unexplained chronic cough should not be ignored," Dr. Khatri said.

Certain associated symptoms further strengthen the suspicion of cancer. The most significant is hemoptysis, the coughing up of blood or blood-stained mucus, even if minimal.

Other red flags include

• unintentional weight loss,
• chest pain,
• breathlessness,
• hoarseness,
• recurrent pneumonia in the same lung region.
• age >40 years,
• smoking history, occupational exposures.

Persistent cough: TB Vs Lung Cancer

Persistent cough also signals the risk of tuberculosis (TB) -- the world's most deadliest infectious disease. Understanding the differences between these two causes is critical for early diagnosis and timely treatment.

Dr Seema Jagiasi from MOC Cancer Care Center told HealthandMe that the cough in TB may sometimes produce blood-tinged phlegm, but it is usually associated with signs of infection, such as fatigue and a general feeling of illness.

TB is more common in younger populations and in individuals with weakened immunity or poor living conditions.

"In contrast, a cough associated with lung cancer tends to be more insidious. It may start as a dry, persistent cough that gradually worsens over time. Unlike TB, it may not initially present with fever or infection-related symptoms," the doctor explained.

Also read: Suffering From Mid-back Pain? Doctors Say It May Be Spinal TB

One of the key differences lies in progression and response to treatment.

TB is treatable with a course of antibiotics, and symptoms often improve within weeks of starting therapy. However, a lung cancer-related cough persists or worsens despite routine medications.

Dr Jagiasi emphasized that any cough lasting beyond three weeks, especially when accompanied by alarming symptoms, should not be ignored.

"Early investigations, such as chest imaging and further diagnostic tests, can help distinguish between the two conditions," the doctor said.

While both TB and lung cancer may present with a persistent cough, their underlying causes, associated symptoms, and progression differ significantly.

The health experts called for more awareness and the need for timely medical evaluation for the effective management of the disease.