With the holiday season high, there is festive cheer, family gatherings and also an undeniable increases in alcohol consumption that fills the air. Christmas and New Year's Eve celebrations to spring break and bachelor parties and sporting events that bring together huge crowds for celebrations mean that drinking becomes synonymous with partying. But behind the revelry lies a much darker behavior: high-intensity drinking.

Alcohol is the most widely used substance in the United States; it has been reported that 84% of adults aged 18 and older reported lifetime use. Moderate drinking is socially acceptable, but high-intensity drinking is an alarming trend. The behavior of consuming eight or more drinks over a few hours for women and 10 or more for men exceeds binge drinking and significantly increases risk for harm.

High-intensity drinking is far from being just a mere passing concern; it is instead a public health crisis. The burden is even greater as 29 million people in the United States suffer from alcohol use disorder. That has caused over 140,000 deaths annually while accounting for 200,000 hospitalizations and 7.4% of visits to emergency departments in the United States. However, only 7.6% of these affected get treated, thus forming a glaring gap in handling this concern.

What Is High-Intensity Drinking?

High-intensity drinking is a dangerous escalation from traditional binge drinking, characterized by consuming double or triple the standard binge amounts. While binge drinking involves four or more drinks for women and five or more for men, high-intensity drinkers often surpass these levels, leading to blood alcohol concentrations (BAC) exceeding 0.2%—a level that significantly impairs judgment and motor skills.

According to Dr. George Koob, the director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), high-intensity drinking is one of the factors that intensify the risks of injuries, overdose, and death. It is also very highly associated with the onset of AUD, since the chance of addiction increases with increased alcohol consumption per occasion.

Blackouts and Memory Loss Risks

One of the most troubling consequences of high-intensity drinking is alcohol-induced blackouts, periods of amnesia where individuals may appear functional but are incapable of forming memories. Blackouts occur when alcohol disrupts the hippocampus, the brain region responsible for memory formation.

Blackouts are often categorized into two types:

1. Fragmentary Blackouts: Characterized by spotty memory, where recalling certain details can trigger partial recollection.

2. En Bloc Blackouts: Significant amnesia for hours, wherein no memory is created at all, even if tried to be recalled.

Aside from memory loss, intense binge drinking is linked with poor decision-making, violence, injury, and conflicts in personal relationships.

Why Holidays and Special Events Are Hotbeds for Excessive Drinking

Holidays and celebrations create the perfect storm for high-intensity drinking. According to research, adults drink nearly double the amount of alcohol during holidays like Christmas and New Year's Eve than they do at any other time of the year. It is during these periods of social gathering, holiday stress, and seasonal sadness that people drink in excess.

For college students, experiences like spring break and 21st birthdays increase the danger. Some studies indicate that students, especially those who travel with buddies to spring break, indulge in more alcohol and make more serious decisions than any student who remains at home or goes with their family to other destinations. Sporting events are, too, notorious for promoting drunk consumption, especially among male customers. Alcohol consumption usually goes high during Super Bowl Sunday, thus leading to games day violence and arrests.

Consequences of Heavy Intensity Drinking

High-intensity drinking impacts not only physical health and mental well-being but also social relationships.

Acute Risks

- Alcohol poisoning

- Severe dehydration and electrolyte imbalances

- Hypoglycemia

- Risky sexual behavior

- Injuries and accidents

Chronic Risks

- Liver damage, alcoholic hepatitis, and cirrhosis

- Cardiovascular diseases such as arrhythmias and cardiomyopathy

- Neurological damage, including memory deficits and blackouts

- Progression to alcohol dependence or AUD

Psychological Impact

High-intensity drinking is strongly linked with increased risks of depression, anxiety, and suicidal ideation. Poor decision-making during episodes can lead to long-lasting consequences, including damaged academic, professional, or personal outcomes.

How to Address the Problem

Combating high-intensity drinking requires education, early intervention, and accessible treatment options. The NIAAA has defined high-intensity drinking to be distinct from binge drinking and has called for targeted approaches to decline prevalence and associated harms.

One promising treatment option is naltrexone, which a medication helps control alcohol cravings. Encouraging in preliminary evidence, more extensive clinical trials will be necessary to ascertain its efficacy more specifically in high-intensity drinkers.

As we head into the holiday season and other special occasions, it is important to heighten awareness of the dangers of high-intensity drinking. A good understanding of long-term consequences and seeking help when alcohol-related issues arise can be the difference between life and death. Celebrations should be about joy and connection, not about the gateway to harm.

If you or someone you know drinks at dangerous levels or have an alcohol use disorder, there is help available. Remember, for suspected cases of alcohol poisoning, dial 911. In this way, we can foster healthier relationships with alcohol and create safer environments for everyone.

American TV personality Oprah Winfrey turned heads at the Paris Fashion Week with her slim figure and sparked talks on the popular weight-loss drug Ozempic.

The now viral videos show Oprah, 72, in jeans and a jacket. Usually seen in parted hair, Oprah also resorted to a ponytail and was wearing tinted sunglasses.

While several netizens expressed concerns about her health, others also spoke about the effects of Ozempic, widely used for weight loss.

“What in the Ozempic Oprah is going on here?”, wrote a user.

“I'm afraid Oprah may OD on Ozempic. Welfare check, please!” another added.

People also commented on the seemingly bigger head and frail body.

“Her head looks way too big for her body. Is it Ozempic or Oprah?” wrote a user.

“She looked good, but she seemed frail,” the netizens said, while another stated, “But having a head that big still is crazy”.

The video also showed Gayle King, another TV host and a longtime friend of Oprah, with a lean figure. Gayle, 71, also rocked a warm-brown look, paired with a fitted top and a black leather jacket.

Does Oprah Winfrey Take Ozempic?

Oprah has openly shared the use of a GLP-1 agonist for weight loss. However, she never mentioned any brand names.

“One of the things that I realized the very first time I took a GLP-1 was that all these years I thought that thin people just had more willpower, they ate better foods, they were able to stick to it longer, they never had a potato chip, and then I realized the very first time I took the GLP-1 that, 'Oh, they're not even thinking about it. They're only eating when they're hungry, and they're stopping when they're full,” Oprah said in a podcast early in 2025.

In 2023, speaking to People, she said she uses the weight-loss medication as a tool to quiet the food noise.

“I now use it as I feel I need it, as a tool to manage not yo-yoing. It quiets the food noise,” she had told the publication.

Oprah's Strength Training Session

In an Instagram post in February 2026, Oprah also showcased her strength training evolution, highlighting the benefits of daily workouts for bone health and her impressive plank progress.

She told her fans that while in 2024, she struggled to hold a plank for more than 10 seconds, now she manages to do a 1-minute plank routine.

Can Ozempic Really Help You Lose Weight?

While Ozempic was originally developed and FDA-approved as an injectable medication to help manage type 2 diabetes, it has gained immense popularity for its ability to produce significant weight loss.

The drug is popular for its active ingredient, semaglutide, which works by mimicking a hormone that regulates blood sugar and appetite.

However, there are several concerns over its side effects. The loss of lean mass, which includes muscle, has emerged as the biggest concern.

Studies have proven that it provides significant weight loss and also reduces major cardiovascular risks and boosts kidney health, among others.

However, common side effects include:

• gastrointestinal (nausea, vomiting, diarrhea, constipation),
• pancreatitis,
• gallbladder issues,
• face sagging
• dental issues like tooth decay, erosion.

She wakes before dawn, packs lunches, manages households, holds careers together, and still finds time to ask everyone else, "Are you okay?" The Indian woman is, in every sense, the backbone of her family. And yet, in giving so much of herself to others, she often becomes the last person she takes care of.

This International Women's Day, that needs to change.

Cancer remains one of the gravest health threats facing Indian women today.

Breast cancer has become the most frequently diagnosed cancer among Indian women — and unlike in Western countries, it is striking women in their 30s and 40s, at the very peak of their lives.

Cervical cancer, though almost entirely preventable, continues to claim thousands of lives every year — not because medicine has failed, but because awareness has.

Ovarian cancer, often called the "silent killer," is frequently caught only at advanced stages, making early vigilance all the more critical.

Thyroid cancer is emerging as a cancer that disproportionately affects women — occurring nearly three times more often in women than men. The good news is that it is also one of the most treatable cancers when detected early.

Women who notice a lump or swelling in the neck, unexplained hoarseness, or difficulty swallowing should not dismiss these signs.

A simple ultrasound and blood test can go a long way in ruling out — or catching — a problem early. The truth, however, is not bleak — it is urgent.

Early Detection Saves Lives

Most cancers, when found at an early stage, are highly treatable. Women above 40 should schedule regular clinical breast examinations and mammography.

Cervical cancer screening through a Pap smear or HPV test, starting as early as age 25–30, can detect precancerous changes before they ever become cancer. These tests are quick, safe, and available — what they need most is for women to simply show up.

Prevention, too, begins with everyday choices. Avoiding tobacco in all its forms — cigarettes, gutka, paan — is the single most powerful step. Regular physical activity, a diet rich in fruits and vegetables, maintaining a healthy weight, limiting alcohol, and getting the "HPV vaccine" (ideally between ages 9 and 14) can dramatically reduce cancer risk.

And perhaps just as importantly: listen to your body. An unusual lump, unexplained bleeding, or a symptom that won't go away is not something to push aside for later. Later can cost everything.

A healthy woman builds a healthy family — and a healthy nation. This Women's Day, let's give every woman around us the most meaningful gift possible: the reminder that her health is not selfish, it is essential.

The 20th-century modernist writer Virginia Woolf, in her book 'Mrs Dalloway', published in 1925, described her 52-year-old protagonist Clarissa Dalloway feeling “shriveled, aged, breastless”, during menopause.

Even after decades, the experience continues to remain widely relatable for scores of women worldwide.

In January this year, author Twinkle Khanna compared menopause to “a phone with a faulty charger.” Several other celebrities, namely Naomi Watts, Oprah Winfrey, Gwyneth Paltrow, and Angelina Jolie, have voiced out their concerns and frustration that women face during the transition.

Menopause is a natural transition in a woman’s life, typically occurring between the ages of 45 and 55. But for millions of women around the globe, its symptoms, which range from hot flashes to night sweats to mood changes and sleep variations, can wreak havoc, affecting professional life, relationships, and physical and mental health.

Hormone replacement therapy (HRT) can be the answer to help ease the symptoms, which are often misunderstood, under-discussed, and sometimes unnecessarily feared.

“Hormone Replacement Therapy (HRT) is an evidence-based option that helps restore hormonal balance during this transition. It is highly effective in relieving menopausal symptoms, improving quality of life,” Dr. Parjeet Kaur, Associate Director, Endocrinology & Diabetes, Medanta, Gurugram, told HealthandMe.

What Is Menopause?

Menopause marks the end of reproductive years for a woman. It occurs when a woman permanently stops menstruating.

Clinically, menopause is diagnosed after 12 consecutive months without a menstrual period.

Most women experience menopause between the ages of 45 and 55, though the transition -- called perimenopause -- can begin several years earlier.

During this time, the ovaries gradually produce less estrogen and progesterone, the hormones that regulate the menstrual cycle. This hormonal decline leads to a range of symptoms, which vary widely among women.

“Menopause is a natural part of biological ageing. It can also be due to medical or surgical procedures. Most women go into menopause between 45 and 55 years,” Dr. Shilpa Agarwal, Consultant Gynecology and Obstetrics and Fetal Medicine Expert, Jaslok Hospital and Research Centre, Mumbai.

“Menopause is caused by the loss of ovarian follicular function and, consequently, a decline in the circulating blood estrogen levels. Natural menopause is deemed to have occurred after 12 consecutive months without menstruation for which there is no other obvious physiological or pathological cause and in the absence of clinical intervention,” she added.

Common symptoms include:

• Hot flashes and night sweats
• Sleep disturbances
• Mood changes and irritability
• Vaginal dryness
• Reduced libido
• Difficulty concentrating
• Weight gain or metabolic changes

While some women experience only mild symptoms, others find that menopause significantly affects their quality of life.

More than the uncomfortable symptoms, the drop in estrogen levels raises a slew of health issues, mainly osteoporosis, heart disease, and sometimes metabolic disorders.

Although regular health checkups, balanced nutrition, and physical activity during midlife are essential to sail through, HRT can play a huge role.

What Is Hormone Replacement Therapy? How Can It Help?

Hormone replacement therapy consists mainly of female hormones, typically estrogen alone or a combination of estrogen and progesterone.

Former First Lady of the US, Michelle Obama, in her podcast in 2020, spoke candidly about her experience of hot flashes.

She described it as a "furnace turning on in her core", and a host of other issues after which she resorted to HRT to maintain her health and lifestyle during that transition.

“Hormone replacement therapy replenishes women with ovarian hormones. HRT typically combines estrogen and progesterone therapy. Progesterone is required in women with an intact uterus to prevent endometrial hyperplasia,” Dr. Agarwal said.

The medications primarily help in

• Reducing hot flashes and night sweats
• Improving sleep and mood
• Treating vaginal dryness and discomfort
• Importantly, HRT helps prevent bone loss and fractures.

Dr. Kaur said that HRT is highly effective in relieving menopausal symptoms, improving quality of life, and supporting bone health by reducing the risk of osteoporosis.

Notably, it can be used in several forms, including pills, skin patches, gels, sprays, and vaginal creams or rings.

Dr. Agarwal recommended that women start HRT within 10 years of menopause or before the age of 60 years".

The experts also advised women to keep monitoring for side effects during HRT.

For many women with moderate to severe menopausal symptoms, HRT can be highly effective.

Studies show that beyond hot flashes, improving sleep, and restoring vaginal health, hormone therapy also

leads to:

• a 25 percent to 50 percent reduction in fatal cardiovascular events,
• a 50 percent to 60 percent reduction in bone fractures,
• a 64 percent reduction in cognitive decline.

Are There Any Risks Involved?

Despite its benefits, HRT has been the subject of debate for decades. Safety concerns intensified after a major US study in the early 2000s linked certain types of hormone therapy to increased risks of breast cancer, blood clots, and stroke.

However, in 2025, the US FDA removed all misleading warnings on the therapy.

Current medical guidelines generally suggest that HRT is safest for healthy women under age 60 or within 10 years of menopause, when used at the lowest effective dose for symptom relief.

“Modern HRT, when carefully selected and monitored, is considered safe for many women. The key is individualized care -- a thoughtful discussion with your doctor can help determine the most suitable approach based on your health profile, age, and personal preferences,” Dr. Kaur said.

Still, HRT may not be advisable for women with a history of:

• Breast or endometrial cancer
• Blood clotting disorders
• Stroke or heart disease
• Certain liver diseases

For these women, non-hormonal treatments -- such as certain antidepressants, lifestyle changes, and alternative medications -- may help manage symptoms.

Menopause is a new phase of life -- and with the right information and guidance, it can be navigated confidently and comfortably, Dr. Kaur said.