With the holiday season high, there is festive cheer, family gatherings and also an undeniable increases in alcohol consumption that fills the air. Christmas and New Year's Eve celebrations to spring break and bachelor parties and sporting events that bring together huge crowds for celebrations mean that drinking becomes synonymous with partying. But behind the revelry lies a much darker behavior: high-intensity drinking.

Alcohol is the most widely used substance in the United States; it has been reported that 84% of adults aged 18 and older reported lifetime use. Moderate drinking is socially acceptable, but high-intensity drinking is an alarming trend. The behavior of consuming eight or more drinks over a few hours for women and 10 or more for men exceeds binge drinking and significantly increases risk for harm.

High-intensity drinking is far from being just a mere passing concern; it is instead a public health crisis. The burden is even greater as 29 million people in the United States suffer from alcohol use disorder. That has caused over 140,000 deaths annually while accounting for 200,000 hospitalizations and 7.4% of visits to emergency departments in the United States. However, only 7.6% of these affected get treated, thus forming a glaring gap in handling this concern.

What Is High-Intensity Drinking?

High-intensity drinking is a dangerous escalation from traditional binge drinking, characterized by consuming double or triple the standard binge amounts. While binge drinking involves four or more drinks for women and five or more for men, high-intensity drinkers often surpass these levels, leading to blood alcohol concentrations (BAC) exceeding 0.2%—a level that significantly impairs judgment and motor skills.

According to Dr. George Koob, the director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), high-intensity drinking is one of the factors that intensify the risks of injuries, overdose, and death. It is also very highly associated with the onset of AUD, since the chance of addiction increases with increased alcohol consumption per occasion.

Blackouts and Memory Loss Risks

One of the most troubling consequences of high-intensity drinking is alcohol-induced blackouts, periods of amnesia where individuals may appear functional but are incapable of forming memories. Blackouts occur when alcohol disrupts the hippocampus, the brain region responsible for memory formation.

Blackouts are often categorized into two types:

1. Fragmentary Blackouts: Characterized by spotty memory, where recalling certain details can trigger partial recollection.

2. En Bloc Blackouts: Significant amnesia for hours, wherein no memory is created at all, even if tried to be recalled.

Aside from memory loss, intense binge drinking is linked with poor decision-making, violence, injury, and conflicts in personal relationships.

Why Holidays and Special Events Are Hotbeds for Excessive Drinking

Holidays and celebrations create the perfect storm for high-intensity drinking. According to research, adults drink nearly double the amount of alcohol during holidays like Christmas and New Year's Eve than they do at any other time of the year. It is during these periods of social gathering, holiday stress, and seasonal sadness that people drink in excess.

For college students, experiences like spring break and 21st birthdays increase the danger. Some studies indicate that students, especially those who travel with buddies to spring break, indulge in more alcohol and make more serious decisions than any student who remains at home or goes with their family to other destinations. Sporting events are, too, notorious for promoting drunk consumption, especially among male customers. Alcohol consumption usually goes high during Super Bowl Sunday, thus leading to games day violence and arrests.

Consequences of Heavy Intensity Drinking

High-intensity drinking impacts not only physical health and mental well-being but also social relationships.

Acute Risks

- Alcohol poisoning

- Severe dehydration and electrolyte imbalances

- Hypoglycemia

- Risky sexual behavior

- Injuries and accidents

Chronic Risks

- Liver damage, alcoholic hepatitis, and cirrhosis

- Cardiovascular diseases such as arrhythmias and cardiomyopathy

- Neurological damage, including memory deficits and blackouts

- Progression to alcohol dependence or AUD

Psychological Impact

High-intensity drinking is strongly linked with increased risks of depression, anxiety, and suicidal ideation. Poor decision-making during episodes can lead to long-lasting consequences, including damaged academic, professional, or personal outcomes.

How to Address the Problem

Combating high-intensity drinking requires education, early intervention, and accessible treatment options. The NIAAA has defined high-intensity drinking to be distinct from binge drinking and has called for targeted approaches to decline prevalence and associated harms.

One promising treatment option is naltrexone, which a medication helps control alcohol cravings. Encouraging in preliminary evidence, more extensive clinical trials will be necessary to ascertain its efficacy more specifically in high-intensity drinkers.

As we head into the holiday season and other special occasions, it is important to heighten awareness of the dangers of high-intensity drinking. A good understanding of long-term consequences and seeking help when alcohol-related issues arise can be the difference between life and death. Celebrations should be about joy and connection, not about the gateway to harm.

If you or someone you know drinks at dangerous levels or have an alcohol use disorder, there is help available. Remember, for suspected cases of alcohol poisoning, dial 911. In this way, we can foster healthier relationships with alcohol and create safer environments for everyone.

Organ transplantation can offer patients with end-stage organ failure a new opportunity for a longer, healthier, and more independent life. However, transplantation is not the end of treatment—it marks the beginning of a lifelong commitment to maintaining the health and function of the transplanted organ.

Successful long-term outcomes depend on close collaboration between the organ recipient, living donor, transplant team, and family. Regular medical follow-up, adherence to prescribed medications, a healthy lifestyle, and early recognition of warning signs are essential for both recipients and living donors.

Care After Organ Transplantation

1. Strict Adherence to Immunosuppressive Medications

For most solid-organ transplant recipients, lifelong immunosuppressive therapy is required to prevent the immune system from attacking the transplanted organ.

Medications such as tacrolimus, cyclosporine, mycophenolate, corticosteroids, and other immunosuppressive agents may be prescribed depending on the type of transplant and the individual patient's condition.

Recipients should:

• Take medications exactly as prescribed and at the recommended times.

• Never stop or reduce immunosuppressive medication without consulting the transplant team.

• Avoid missing doses.

• Inform their transplant physician before starting any new medication.

Even seemingly minor changes in medication can affect drug levels and may increase the risk of acute or chronic rejection.

Also read: World Organ Donation Day 2026: Too Old Or Too Sick To Donate Organs? Doctors Bust Key Myths

2. Regular Follow-Up and Laboratory Monitoring

Regular follow-up with the transplant team is an essential component of lifelong transplant care.

Depending on the transplanted organ and individual circumstances, monitoring may include:

• Kidney and liver function tests

• Complete blood counts

• Immunosuppressive drug levels

• Blood pressure and blood glucose monitoring

• Urine examination in kidney transplant recipients

• Imaging or other investigations when clinically indicated

These evaluations help detect rejection, infection, medication toxicity, or deterioration in graft function at an early stage, sometimes before symptoms become apparent.

Also read: US HHS Action Against Kentucky Organ Donation Group Raises Questions About Transplant Safety

3. Recognizing Warning Signs

Transplant recipients should promptly contact their transplant team if they develop symptoms such as:

• Unexplained or persistent fever

• Chills or significant weakness

• Reduced urine output, particularly after kidney transplantation

• Swelling or sudden weight gain

• Breathlessness or persistent cough

• Persistent pain over the transplant site

• Persistent vomiting or diarrhoea

• Unexplained changes in blood pressure or blood sugar

Because immunosuppressive medications reduce the body's immune response, infections may develop more easily and may sometimes present with subtle symptoms. Early medical assessment is therefore important.

4. Infection Prevention

Transplant recipients are more susceptible to infections, particularly during periods of intensive immunosuppression.

Important preventive measures include:

• Practising regular hand hygiene

• Avoiding close contact with individuals who have contagious infections

• Following appropriate food-safety precautions

• Drinking safe and hygienic water

• Maintaining good personal hygiene

• Keeping vaccinations up to date as advised by the transplant team

• Seeking medical advice promptly if symptoms of infection develop

Recipients should also follow the specific infection-prevention recommendations provided by their transplant centre.

5. Healthy Nutrition and Lifestyle

A balanced and nutritious diet is an important component of long-term transplant health.

Recipients should aim to:

• Maintain a healthy body weight

• Eat a balanced diet rich in vegetables, fruits, whole grains, and appropriate sources of protein

• Maintain adequate hydration unless fluid restriction has been advised

• Limit excessive salt, sugar, and processed foods

• Exercise regularly according to their medical condition and physician's advice

• Avoid smoking and tobacco products

• Avoid excessive alcohol consumption

Certain foods, supplements, and herbal preparations may interact with immunosuppressive medications. No dietary supplement, herbal preparation, or over-the-counter medication should be started without discussing it with the transplant team.

Also read: AIIMS Performs Second Dual Kidney Transplant Using Organs From 70-Year-Old Donor: How It Can Expand Donor Pool?

Post-Donation Care for Living Organ Donors

Living organ donation is a remarkable act of generosity. However, protecting the donor's long-term health remains the highest priority.

After donation, the donor should remain under appropriate medical supervision and follow the recommendations of the transplant and surgical team.

1. Recovery After Donation

The recovery period varies depending on the type of donation and the individual's overall health.

Donors should:

• Follow wound-care instructions carefully.

• Take prescribed medications as directed.

• Get adequate rest during the initial recovery period.

• Gradually resume physical activity as advised.

• Avoid strenuous exercise and heavy lifting until medically cleared.

• Return to work and normal activities progressively.

The recovery process should be individualized rather than based solely on a fixed timeline.

2. Long-Term Health After Kidney Donation

Most carefully selected kidney donors can lead healthy, active lives with a single functioning kidney.

Long-term health recommendations include:

• Maintaining a healthy body weight

• Exercising regularly

• Eating a balanced diet

• Staying adequately hydrated

• Avoiding tobacco

• Avoiding unnecessary use of potentially kidney-toxic medications, particularly certain painkillers such as NSAIDs

• Monitoring blood pressure

• Periodically checking kidney function and urine as recommended

Living donation should never mean that donors stop looking after their own health. The donor's well-being remains a lifelong priority.

Any new or persistent symptoms should be reported to a healthcare professional.

Also read: India Records 20,138 Organ Transplants In 2025; Deceased Donor Transplants Reach 3,526

3. Emotional and Psychological Well-Being

Transplantation and organ donation can have a significant emotional impact on both recipients and donors.

Recipients may experience anxiety related to rejection, medication, financial concerns, or the uncertainty associated with transplantation. Living donors may also experience emotional changes during the recovery period.

Maintaining open communication with family members and the transplant team can be extremely helpful. If persistent anxiety, depression, sleep disturbances, or emotional distress develops, professional psychological or psychiatric support should be sought.

4. The Importance of Lifelong Follow-Up

The success of organ transplantation depends not only on the surgical procedure but also on long-term post-transplant care.

For recipients, medication adherence, regular monitoring, infection prevention, and a healthy lifestyle are essential to preserving graft function.

For living donors, appropriate postoperative recovery, long-term health monitoring, and healthy lifestyle practices help ensure that they continue to live healthy and fulfilling lives after donation.

The transplant may be a single surgical event—but maintaining the gift of life is a lifelong journey.

With appropriate medical supervision, adherence to treatment, healthy lifestyle choices, and timely attention to warning signs, organ recipients can protect the health of their transplanted organ, while living donors can continue to enjoy a healthy and active life after their selfless contribution.

By Dr. Pragnesh Desai, Senior Director & HOD – Urology, Renal Transplant, Robotics & Uro-Oncology, Yatharth Super Speciality Hospital, Noida Extension

Organ donation is one of the most generous gifts a person can give. Age, diabetes, hypertension or other medical conditions do not automatically rule out organ donation, doctors said on World Organ Donation Day.

Observed on August 13 every year, World Organ Donation Day aims to raise awareness about the need for organ and tissue donation and honour donors and their families.

Organ Donation After Brain Death

Dr. Umesh Gupta, Director and HOD, Nephrology and Kidney Transplant, Aakash Healthcare Multi-Speciality Hospital, Dwarka, told HealthandMe that organ donation can be considered when brain function is permanently lost and cannot be restored.

Brain death occurs when all functions of the brain and brainstem have permanently stopped.

“Brain death is different from a coma or a prolonged unconscious state. In brain death, the person cannot regain consciousness or breathe independently. Mechanical support may continue to keep the heart beating and preserve the condition of organs for a limited period, which is why organ donation can be considered,” he said.

Depending on the donor’s medical condition, organs such as the heart, liver, kidneys, lungs and pancreas may be suitable for transplantation.

Who Can Donate Organs?

Age alone does not rule out organ donation. Eligibility is assessed individually by the transplant team.

Doctors evaluate:

• Health and functioning of individual organs
• Existing illnesses
• Infections
• Medical history
• Other factors that could affect transplant safety

Can People With Diabetes or Hypertension Donate?

People with well-controlled diabetes or hypertension may still be eligible to donate certain organs or tissues, said Dr. Shailesh Chandra Sahay, Senior Director - Urology, Kidney Transplant, Robotic Surgery, Max Super Speciality Hospital, Patparganj.

Modern transplantation practices allow doctors to assess each organ individually rather than excluding a donor solely because of age or a particular diagnosis.

Every potential donor deserves a medical evaluation. An organ that may appear unsuitable to a person could ultimately give another patient a second chance at life.

Blood Group Is Important — But Not the Only Factor

Blood group compatibility is an important consideration in organ transplantation.

“A blood group O donor typically donates to O recipients, while AB recipients can receive organs from all ABO blood groups in many transplant settings,” Dr. Saurabh said.

However, compatibility involves more than blood type. Doctors also assess:

• Tissue compatibility
• Antibodies
• Organ size
• Recipient’s overall health

World Organ Donation Day 2026: Why Donation Matters

• One deceased donor can potentially save up to eight lives through vital organ donation.
• Tissue donation can improve the lives of many more people.
• A record 173,727 solid-organ transplants were performed worldwide in 2024, but demand continues to exceed supply.
• India performed 20,019 organ transplants in 2025, nearly four times the number in 2013.
• As of March 3, 2026, 89,839 patients were on India’s national waiting list for major organs.
• Only around 18% of transplants currently involve deceased-donor organs.
• More than 4.8 lakh Indians have pledged to donate organs and tissues after death since September 2023.

Lung cancer has long been associated with smoking, but this is no longer the complete picture. While tobacco remains the leading cause, an increasing number of people who have never smoked are also being diagnosed with the disease. This changing pattern highlights the need to look beyond smoking alone when considering lung cancer risk.

In non-smokers, lung cancer is often diagnosed later because neither patients nor families may initially suspect the disease. As a result, symptoms are sometimes mistaken for common respiratory illnesses, delaying evaluation and treatment.

Why Non-Smokers Are Also at Risk

While smoking continues to account for most lung cancer cases, several other factors can also contribute. Long-term exposure to second-hand smoke, air pollution, radon gas, asbestos, diesel exhaust, and certain workplace chemicals has been linked to an increased risk. A family history of lung cancer or specific genetic mutations may also make some individuals more susceptible, even if they have never used tobacco.

In urban areas, prolonged exposure to polluted air is becoming an important concern. Fine particulate matter can enter deep into the lungs, causing long-term inflammation and damage that may increase the risk of developing lung disease, including cancer.

Symptoms That Should Not Be Ignored

Early lung cancer may not cause noticeable symptoms. When symptoms do appear, they should not be ignored, particularly if they persist for more than a few weeks. Symptoms that should be evaluated by a doctor include:

• A persistent cough that does not improve

• Coughing up blood

• Chest pain

• Shortness of breath

• Unexplained weight loss

• Repeated chest infections

• Hoarseness of voice

• Persistent fatigue

These symptoms can occur due to several conditions and do not always indicate lung cancer. However, persistent or worsening symptoms should be assessed promptly to identify the underlying cause and begin appropriate treatment if needed.

Why Early Diagnosis Makes a Difference

Finding lung cancer at an early stage improves the chances of successful treatment. Individuals with prolonged exposure to environmental or occupational risk factors, or those with a strong family history of lung cancer, should discuss their risk with a doctor. Imaging tests such as chest CT scans and, when indicated, molecular testing help identify the type of lung cancer and support treatment planning.

Looking Beyond Smoking

Not every case of lung cancer can be prevented, but reducing exposure to tobacco smoke, avoiding harmful occupational exposures, improving indoor air quality where possible, and seeking medical advice for persistent respiratory symptoms can help protect lung health. Greater awareness that lung cancer can affect both smokers and non-smokers may lead to earlier diagnosis, timely treatment, and better outcomes.

(Dr Dipanjan Panda, Senior Consultant, Medical Oncology, Indraprastha Apollo Hospital, Delhi)