With the holiday season high, there is festive cheer, family gatherings and also an undeniable increases in alcohol consumption that fills the air. Christmas and New Year's Eve celebrations to spring break and bachelor parties and sporting events that bring together huge crowds for celebrations mean that drinking becomes synonymous with partying. But behind the revelry lies a much darker behavior: high-intensity drinking.

Alcohol is the most widely used substance in the United States; it has been reported that 84% of adults aged 18 and older reported lifetime use. Moderate drinking is socially acceptable, but high-intensity drinking is an alarming trend. The behavior of consuming eight or more drinks over a few hours for women and 10 or more for men exceeds binge drinking and significantly increases risk for harm.

High-intensity drinking is far from being just a mere passing concern; it is instead a public health crisis. The burden is even greater as 29 million people in the United States suffer from alcohol use disorder. That has caused over 140,000 deaths annually while accounting for 200,000 hospitalizations and 7.4% of visits to emergency departments in the United States. However, only 7.6% of these affected get treated, thus forming a glaring gap in handling this concern.

What Is High-Intensity Drinking?

High-intensity drinking is a dangerous escalation from traditional binge drinking, characterized by consuming double or triple the standard binge amounts. While binge drinking involves four or more drinks for women and five or more for men, high-intensity drinkers often surpass these levels, leading to blood alcohol concentrations (BAC) exceeding 0.2%—a level that significantly impairs judgment and motor skills.

According to Dr. George Koob, the director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), high-intensity drinking is one of the factors that intensify the risks of injuries, overdose, and death. It is also very highly associated with the onset of AUD, since the chance of addiction increases with increased alcohol consumption per occasion.

Blackouts and Memory Loss Risks

One of the most troubling consequences of high-intensity drinking is alcohol-induced blackouts, periods of amnesia where individuals may appear functional but are incapable of forming memories. Blackouts occur when alcohol disrupts the hippocampus, the brain region responsible for memory formation.

Blackouts are often categorized into two types:

1. Fragmentary Blackouts: Characterized by spotty memory, where recalling certain details can trigger partial recollection.

2. En Bloc Blackouts: Significant amnesia for hours, wherein no memory is created at all, even if tried to be recalled.

Aside from memory loss, intense binge drinking is linked with poor decision-making, violence, injury, and conflicts in personal relationships.

Why Holidays and Special Events Are Hotbeds for Excessive Drinking

Holidays and celebrations create the perfect storm for high-intensity drinking. According to research, adults drink nearly double the amount of alcohol during holidays like Christmas and New Year's Eve than they do at any other time of the year. It is during these periods of social gathering, holiday stress, and seasonal sadness that people drink in excess.

For college students, experiences like spring break and 21st birthdays increase the danger. Some studies indicate that students, especially those who travel with buddies to spring break, indulge in more alcohol and make more serious decisions than any student who remains at home or goes with their family to other destinations. Sporting events are, too, notorious for promoting drunk consumption, especially among male customers. Alcohol consumption usually goes high during Super Bowl Sunday, thus leading to games day violence and arrests.

Consequences of Heavy Intensity Drinking

High-intensity drinking impacts not only physical health and mental well-being but also social relationships.

Acute Risks

- Alcohol poisoning

- Severe dehydration and electrolyte imbalances

- Hypoglycemia

- Risky sexual behavior

- Injuries and accidents

Chronic Risks

- Liver damage, alcoholic hepatitis, and cirrhosis

- Cardiovascular diseases such as arrhythmias and cardiomyopathy

- Neurological damage, including memory deficits and blackouts

- Progression to alcohol dependence or AUD

Psychological Impact

High-intensity drinking is strongly linked with increased risks of depression, anxiety, and suicidal ideation. Poor decision-making during episodes can lead to long-lasting consequences, including damaged academic, professional, or personal outcomes.

How to Address the Problem

Combating high-intensity drinking requires education, early intervention, and accessible treatment options. The NIAAA has defined high-intensity drinking to be distinct from binge drinking and has called for targeted approaches to decline prevalence and associated harms.

One promising treatment option is naltrexone, which a medication helps control alcohol cravings. Encouraging in preliminary evidence, more extensive clinical trials will be necessary to ascertain its efficacy more specifically in high-intensity drinkers.

As we head into the holiday season and other special occasions, it is important to heighten awareness of the dangers of high-intensity drinking. A good understanding of long-term consequences and seeking help when alcohol-related issues arise can be the difference between life and death. Celebrations should be about joy and connection, not about the gateway to harm.

If you or someone you know drinks at dangerous levels or have an alcohol use disorder, there is help available. Remember, for suspected cases of alcohol poisoning, dial 911. In this way, we can foster healthier relationships with alcohol and create safer environments for everyone.

Weight-loss jabs, or GLP-1 receptor agonists, have provided many people with results that diets alone could not achieve. For those struggling with constant cravings, these medications have quieted the persistent “food noise” that often drives overeating. They have transformed not only body shapes but also self-confidence and daily habits.

Yet questions remain: can people safely stop taking these drugs, and what happens to the body when they do? These are still largely unknown, as the drugs are relatively new. GLP-1s mimic a natural hormone that controls hunger, but the long-term effects are only beginning to be understood. Additionally, for the estimated 1.5 million people in the UK paying privately for these injections, maintaining treatment can be costly.

Two women, Tanya and Ellen, share their personal experiences with the BBC on weight-loss jabs and what life was like when they attempted to stop.

Weight Loss Jabs: Tanya Hall’s Experience

Tanya, a sales manager in the fitness industry, initially started taking Wegovy to challenge her own perceptions about weight and authority. She often felt overlooked or undervalued because of her size, and hoped that losing weight would change how others treated her, as per BBC.

Early in treatment, Tanya experienced side effects including nausea, headaches, sleep issues, and hair loss, which she describes as clumps coming out. Despite this, she steadily lost weight—six stone (38 kg) over 18 months—and the injections quieted the relentless urge to eat.

However, every time she tried to stop, her appetite surged within days, leaving her horrified at her own eating. Now, Tanya continues the medication, feeling it has become essential to maintaining her weight and the confidence it brings.

Weight Loss Jabs: What Happens To Your Body When You Stop Taking Them?

Wegovy’s manufacturer, Novo Nordisk, stresses that treatment decisions should be made with medical guidance and that side effects must be considered. Lifestyle GP Dr. Hussain Al-Zubaidi likens stopping GLP-1s abruptly to being hit by a “tsunami” of hunger.

Research shows that within one to three years of stopping these medications, people can regain 60–80% of the weight they lost. This highlights how these drugs work not just by reducing appetite temporarily but by fundamentally altering hunger cues.

Weight Loss Jabs: Ellen Ogley’s Journey

Ellen turned to Mounjaro after reaching a critical point in her life. Her weight had put her at risk during surgery, and emotional binge eating dominated her daily habits. Once on the medication, Ellen noticed her compulsive eating completely stopped.

Over 16 weeks, she lost 3 st 7 lb (22 kg) and began tapering off the injections over six weeks. She focused on developing a healthier relationship with food, creating balanced meals, and incorporating exercise into her routine. Despite some weight creep after stopping, she has since lost a total of 51 kg and now feels confident her habits are sustainable.

Weight Loss Jabs: The Importance of Support

Dr. Al-Zubaidi emphasizes that exiting GLP-1 treatment safely requires guidance and long-term support. NICE recommends at least a year of tailored advice after stopping injections to help individuals maintain their weight and prevent relapse, as per BBC.

For patients paying privately, such structured support may not always be available, increasing the risk of regaining weight. Lifestyle, mindset, and environmental factors play a significant role in long-term outcomes.

Tanya has chosen to continue with her medication, aware of the pros and cons, while Ellen has closed that chapter and built a sustainable routine for life after Mounjaro.

Weight-loss jabs can dramatically change appetite and body weight, but stopping them can be challenging. The transition off these drugs requires careful planning, support, and lifestyle adjustments. As Tanya and Ellen’s experiences show, the journey varies by individual, and long-term strategies are essential to maintaining health and weight loss results.

Eli Lilly, the manufacturer of Mounjaro, states that patient safety is its top priority and that it continually monitors and reports information on treatment outcomes to regulators and prescribers.

Flu Symptoms: Seasonal infections are spreading across the United States just as the holiday travel rush gets underway, worrying health officials about fresh spikes during family get-togethers. Flu and norovirus cases are rising in several states, while COVID-19 continues to circulate at lower but consistent levels. Together, these illnesses are adding strain on hospitals as millions of people plan to travel in the days ahead.

Flu: What Is Super Flu?

“Super flu” is not a clinical term, but it is often used to describe a flu season that feels more aggressive or spreads faster than usual. This is typically linked to a dominant strain of influenza A. The current surge is being driven by a mutated influenza A strain known as H3N2 subclade K. Health officials say this strain has become the leading flu variant in the US, accounting for roughly 89 percent of H3N2 samples analysed since late September, according to genetic sequencing data from the Centers for Disease Control and Prevention (CDC).

This variant emerged after the 2025–26 flu vaccine was formulated, meaning the vaccine may not be as closely matched as in earlier seasons. While the shot still offers protection against severe disease, experts note that the mismatch could allow the virus to spread more easily.

Flu Symptoms 2025: What Symptoms Should People Watch For?

The symptoms seen in the current flu wave are largely familiar. People may develop fever, chills, extreme tiredness, cough, and body aches. Doctors, however, caution that the wider spread could result in more serious cases, particularly among people who are at higher risk.

CDC estimates indicate that the US has already seen about 4.6 million flu cases this season, along with nearly 49,000 hospital admissions and around 1,900 deaths. Flu activity increased sharply in mid-December, with test positivity jumping from 8.1 percent to 14.3 percent within a single week.

Flu Symptoms 2025: How To Reduce The Risk

Doctors recommend staying home when feeling unwell, washing hands often, especially to limit norovirus spread, and considering vaccination against flu and COVID-19. Even when the strain match is not ideal, experts stress that vaccines remain crucial in reducing the risk of severe illness, hospitalisation, and death.

Flu Cases In The US: How Contagious Is Superflu?

In terms of how easily it spreads, it behaves much like regular flu, which is known to be highly contagious.

Someone with flu can pass on the virus from around one day before symptoms appear and continue to be contagious for five to seven days after becoming sick. Children, older adults, and those with weakened immune systems may remain infectious for a longer period.

The virus mainly spreads through respiratory droplets released when an infected person coughs, sneezes, speaks, or breathes near others. It can also spread through contact with contaminated surfaces, followed by touching the mouth, nose, or eyes. Crowded indoor settings, poor airflow, and close contact make transmission far more likely, which explains why flu spreads quickly during peak season.

What makes a so-called “super flu” seem more contagious is not a new way of spreading, but higher case numbers, quicker community transmission, and stronger symptoms, all of which increase coughing, fever, and the amount of virus released.

The NHS has urged people using a commonly prescribed medication to seek urgent medical advice if they notice any of three specific symptoms. These are linked to some of the more serious complications associated with dapagliflozin. Sold under the brand name Forxiga, dapagliflozin is mainly used to treat type 2 diabetes. It is also prescribed for people with heart failure and chronic kidney disease. While exact figures on how many prescriptions are issued each year in the UK are not publicly available, the drug is among the costliest for the health service, with NHS spending estimated at around £300 million a year in England alone.

What Is Dapagliflozin?

Dapagliflozin belongs to a group of medicines known as SGLT2 inhibitors. It works by helping the kidneys remove excess glucose from the body through urine, which lowers blood sugar levels. Beyond diabetes, the drug has been shown to reduce the risk of hospitalisation in people with heart failure and slow the progression of chronic kidney disease. It may be prescribed on its own or alongside other treatments, depending on a patient’s condition and overall health.

Medicines That Contain Dapagliflozin

Dapagliflozin can also be prescribed in combination with other diabetes medicines. These include Xigduo, which combines dapagliflozin with metformin, and Qtern, which pairs dapagliflozin with saxagliptin.

Dapagliflozin Symptoms That Require Urgent Medical Advice

However, the NHS warns on its website that, “like all medicines,” dapagliflozin can cause side effects in some people. Patients are advised to “call your doctor or call 111 now” if they experience:

• A very dry or sticky mouth, intense thirst, feeling sleepy or unusually tired, little or no urination, and a fast heartbeat, which may be signs of dehydration
• A high temperature, or feeling hot, cold or shivery, pain or burning when passing urine, pain in the back or side, or blood in the urine, which could point to a urinary tract infection
• Severe pain, tenderness, redness or swelling in the groin or perineal area, along with a high temperature or feeling generally unwell, which may signal a rare but serious infection called Fournier’s gangrene

Dapagliflozin: How Common Are These Side Effects?

These reactions are classed as rare, affecting fewer than one in 10,000 people. More common side effects occur in over one in 100 users. The NHS says: “They’re usually mild and do not last long. There are things you can do to help cope with them.”

Dapagliflozin Side Effects

The NHS lists the following as more frequent side effects:

• Thrush
• Back pain
• Passing urine more often
• Dizziness
• Mild skin rashes

Taking dapagliflozin alongside other diabetes medicines, such as insulin or sulfonylureas like gliclazide, can sometimes cause blood sugar levels to drop too low. Some people may also develop diabetic ketoacidosis (DKA).

What Is Diabetic Ketoacidosis?

DKA happens when the body lacks enough insulin and harmful acids, known as ketones, build up in the blood. Warning signs can include nausea or vomiting, extreme thirst, confusion or severe tiredness, stomach pain, fruity-smelling breath, and fast or deep breathing. The NHS notes that symptoms usually develop within 24 hours, though they can appear more quickly.

When To Seek Emergency Help

Patients are taught how to monitor their blood sugar and ketone levels and what steps to take if symptoms appear. Emergency services should be contacted immediately by calling 999 if a person experiences a severe allergic reaction, known as anaphylaxis, after taking dapagliflozin.