The COVID-19 pandemic may be over, but our immune systems are still feeling the impact. After years of battling constant viral threats, from COVID-19 to seasonal flu and other infections, our body’s defense system is exhausted. Many people continue to experience lingering inflammation, frequent illnesses, and slower recovery times. This extended state of immune stress has compromised us further to chronic illness, including autoimmune diseases and even neurodegenerative diseases such as Parkinson's. So why is our immune system still in trouble? And how do we give it its power back? Understanding immune exhaustion is the beginning of rebuilding our body's natural immunity.

A weakened immune system makes people more susceptible to disease, mental illnesses, and even sleep disorders. Now, new research indicates that immune system depletion may play an important role in the onset of Parkinson's disease, a degenerative neurologic disorder that compromises movement and cognition.

Role of Inflammation in Parkinson's Disease

Dysfunctional immune response is a leading cause of long-standing inflammation within the body, that has been found to contribute towards a multitude of conditions, including cardiovascular conditions, diabetes, depression, and neurodegenerative diseases such as Alzheimer's.

As people age, their immune system naturally becomes less effective. This deterioration, referred to as immune exhaustion, may be a key contributor to the onset and progression of Parkinson’s disease. Rebecca Wallings, a Parkinson’s Foundation Launch Award grant recipient and senior postdoctoral fellow at the University of Florida, believes that an accumulation of exhausted immune cells could be driving neurodegeneration in Parkinson’s patients.

How a Tired Immune System Might Affect Parkinson's?

Parkinson's disease is most commonly linked with the degeneration and loss of dopaminergic neurons—motor nerve cells that produce dopamine, an essential neurotransmitter for movement. While researchers have long suspected inflammation is involved in this neurodegeneration, the mechanisms are not yet well understood.

Wallings' study is on immune cell exhaustion, a process by which aging immune cells fail to control immune responses effectively. Her research indicates that instead of dampening inflammation in Parkinson's patients, attempts should be made to rejuvenate the immune system to regain its functionality.

Energy Deficiency in Immune Cells

One of the major findings of Wallings' work is the function of mitochondrial impairment in immune cell exhaustion. Mitochondria are commonly called the powerhouses of cells, as they are vital for generating energy. As mitochondria age and become inefficient, immune cells fail to function well, potentially accelerating neurodegeneration in Parkinson's disease.

Wallings has found that mutations in the LRRK2 gene, a recognized genetic risk factor for Parkinson's disease, are linked with defective mitochondrial function and immune cell exhaustion. Her current work includes testing various therapeutic approaches to restore mitochondrial function in immune cells with the potential to enhance the immune system and potentially prevent or treat Parkinson's disease.

Will Rejuvenating the Immune System Help in Treatment?

For decades, the standard practice in treating Parkinson's has been to suppress brain inflammation. Yet Wallings' work indicates that instead of slowing down immune responses, restoring the immune system could be a more successful strategy. By addressing mitochondrial impairment and immune resilience, researchers can potentially reverse or slow down Parkinson's disease.

Wallings is now looking into how to rejuvenate immune cells by fixing mitochondria. She studies immune cells from patients with Parkinson's as well as from healthy subjects and performs experiments on animal models to determine if rejuvenation of the immune system could result in improved disease outcomes.

Lifestyle Factors That May Affect Parkinson's Risk

While there is no cure for Parkinson's disease, some lifestyle adjustments may decrease the chances of developing the illness. Since neurodegenerative diseases are associated with chronic inflammation and immune dysfunction, developing habits that enhance immune function might prove helpful.

Diet: There is evidence to suggest that eating in accordance with the Mediterranean or MIND diets, both high in antioxidants, healthy fats, and anti-inflammatory foods, can encourage brain wellness and reduce Parkinson's risk.

Avoiding Dangerous Substances: Restricting alcohol and nicotine use can maintain a robust immune system and suppress inflammation.

Reducing Stress: Chronic stress weakens immune function, so methods such as meditation, exercise, and sufficient sleep can lead to improved overall well-being.

As adenovirus cases continue to rise globally, health professionals have noticed that this potentially serious infection is sometimes being mistaken for another illness, what many are calling the ‘super flu’.

For those unfamiliar, adenovirus is a DNA virus that gradually affects a person’s upper and lower respiratory tract, as well as other organs. This can include the eyes, digestive system, and kidneys.

Adenovirus Or Super Flu?

According to Dr. Deborah Lee at Dr Fox Online Pharmacy, who spoke to Cosmopolitan: "It spreads when someone breathes in infected droplets, touches the virus and then rubs their eyes, or through the faecal-oral route (not washing hands properly after using the toilet)."

"It moves quickly in crowded spaces where people are close together." She added, "The virus is resistant to soap and many commonly used cleaning products."

Adenovirus: What Are The Symptoms?

The reassuring news about adenovirus is that most people recover within a week or two. Its symptoms are often similar to those of a common cold.

Typical signs include fever, runny nose, sore throat, cough, shortness of breath, and swollen lymph nodes in the neck. In more severe cases, patients may also experience conjunctivitis, ear pain, diarrhea, vomiting, stomach aches, or urinary tract infections.

Certain groups are at higher risk of serious illness. Dr. Lee notes, "Babies and children under five, older adults, pregnant women, and people with weakened immune systems are the most vulnerable."

Although adenovirus symptoms often resemble those of a typical flu, it’s important to know when someone is dealing with the flu—or worse, the current ‘super flu’ that’s circulating widely.

How Does Adenovirus Differ From The 'Normal' Flu?

One way to tell the difference is by how long someone is sick. Adenovirus tends to develop gradually, whereas the ‘normal’ flu often hits suddenly, with high fever and intense symptoms within hours, Lee explains. Common flu symptoms also include a high temperature (38–40°C), severe headache, and extreme fatigue.

Other key differences: adenovirus can occur throughout the year, while flu is mostly seasonal. Adenovirus can also cause pink eye and gastrointestinal problems like vomiting or diarrhea, but it’s less likely to lead to serious complications compared to flu.

What About The 'Super Flu'?

Doctors say it’s not only the regular flu that needs to be distinguished from adenovirus, but also the current ‘super flu,’ which is causing particularly dramatic symptoms.

This infection is caused by the H3N2 virus and tends to be more severe than typical winter illnesses, especially in the UK.

"Past data shows H3N2 has been linked to more hospitalizations and deaths from flu, especially among adults over 65 and young children, compared with other flu types," Lee explained. When comparing the ‘super flu’ to adenovirus, she notes that the symptoms are very similar.

However, she stresses that the ‘super flu’ is considered much more intense. Not only can your sore throat feel agonizing, but aches and pains may be strong enough to confine you to bed.

Adenovirus vs Super Flu: Symptoms Explained

While adenovirus and the so-called ‘super flu’ can feel very similar, there are subtle differences to watch for. Adenovirus usually develops gradually, with fever, cough, sore throat, runny nose, and sometimes pink eye or digestive upset. Most healthy individuals recover within a week or two. In contrast, the ‘super flu,’ caused by the H3N2 virus, hits hard and fast—high fever, intense body aches, severe fatigue, and an agonizing sore throat are common.

Both illnesses can affect vulnerable groups such as young children, the elderly, and immunocompromised individuals, but the super flu tends to bring more extreme symptoms that may require hospitalization. Understanding these distinctions can help people recognize the illness early and seek appropriate care.

Have you ever described feeling “cold feet,” “a gut instinct,” or “a shiver down your spine”? These common expressions might seem trivial, but they reflect something real. Emotional body mapping can help explain why.

Just as anxiety or depression can show up as physical symptoms, our emotions often register in specific areas of the body. Emotions guide much of how we experience the world, yet many of us rarely stop to notice how they affect us physically.

If you struggle to put your feelings into words, learning how emotions manifest in the body can help you connect more deeply with yourself.

Where Are Emotional Feelings Felt In Your Body?

A 2014 study by Glerean and colleagues identified 13 emotions and the specific areas of the body they activate—or don’t. Similar to a heat map, warmer colors (red, orange, yellow) indicate increased activity, while cooler colors (blue, green, indigo) indicate decreased activity.

If these maps resonate with your own experiences, they can provide insight into how emotions influence your body and overall well-being.

How Was This Tested?

The researchers proposed that each emotion triggers distinct physical reactions. They asked 701 participants to shade regions on a body silhouette where they felt heightened or reduced activity in response to various stimuli.

These stimuli mirrored real-life experiences: clips from films, conversations, and unexpected facial expressions. Across the participant pool, emotions consistently affected similar areas of the body.

A follow-up study in 2018 by the same team found that the intensity of bodily sensations mirrored the intensity of the emotion in the mind. In other words, stronger physical feelings were linked with stronger mental experiences.

From this, researchers categorized feelings as:

• Negative (unpleasant): anger, fear, anxiety, shame
• Positive (pleasant): happiness, love, pride
• Other categories: illness, homeostasis, cognition

Few emotions, such as surprise, were found to be neutral. Participants also reported that pleasant and controllable states occurred more often than unpleasant and uncontrollable ones. Anyone who has experienced overwhelming anxiety or depression will recognize that feeling of being out of control.

Emotional Body Chart

Certain emotions trigger strong physical responses, often preparing the body for action, such as the fight-or-flight response.

• Happiness: This emotion lights up the body the most. Warm sensations spread throughout, especially in the head and chest, signaling energy, vitality, and a sense of well-being.
• Anger: Activation is intense in the upper body—the head, chest, and arms. The hands are especially bright, reflecting the impulse to clench fists or act aggressively.
• Fear: Like anger, it activates the head and chest (heart racing). However, the feet are cold (blue), suggesting blood is being redirected from the extremities to vital organs.
• Anxiety: Almost entirely focused in the chest, representing tightness, rapid heartbeat, or difficulty breathing.
• Love & Pride: Both emotions show strong activation in the chest and head, associated with warmth, heart swelling, or the sensation of “puffing up” the chest.

Deactivation Emotions (Mostly Blue):

These emotions involve a withdrawal of energy and sensation from the body.

• Depression: The most deactivated state. Limbs are entirely blue, showing heaviness, numbness, and a lack of energy to move. The torso shows very little activation.
• Sadness: A mix of responses. The chest and eyes show some activity (linked to crying or heartache), but the arms and legs are cool, reflecting slowing or weakening of the body.

Other Specific Reactions:

• Disgust: Activation is concentrated in the digestive system—the throat and stomach—indicating nausea or physical aversion.
• Shame: A complex pattern appears. The chest and cheeks are warm (blushing), while the extremities are cold, reflecting internal turmoil paired with external withdrawal.

Understanding where emotions manifest in the body can help us become more aware of our physical and mental states. From the warmth of happiness in the chest to the heaviness of depression in the limbs, our bodies carry the signals of our feelings. Paying attention to these sensations not only deepens self-awareness but can also guide us in managing stress, improving well-being, and responding to emotions more mindfully.

Catching a cold during winter is fairly common because viruses spread more easily in packed indoor settings, and cold weather can weaken the immune defence inside the nose, making it harder to fight infections. Having a stuffy nose or a mild cough is one thing, but many people often confuse their illness with a cold when it may actually be flu. Flu symptoms are usually more intense and can include fever, headaches and body aches, along with a dry cough and sore throat. A cold, on the other hand, tends to peak within two to three days, with recovery usually taking about a week.

Cold vs Flu: Why Knowing the Difference Matters

With a strong flu strain causing disruption across the UK, knowing how to tell the difference between a cold and flu has become especially important. Berkshire NHS, which has around 17,100 followers on TikTok, has outlined three key differences between the two illnesses.

In a caption, the community NHS trust said: “Cold and flu symptoms can look similar, but flu is usually more severe. The flu vaccine helps protect against flu. Visit the NHS website to learn more.”

NHS Shares 3 Symptoms to Tell Cold and Flu Apart

The video features an NHS staff member pointing out three signs as she walks toward the correct option. The first is that flu comes on suddenly, often within a few hours, while a cold mainly affects the nose and throat. The final sign is that flu can leave you feeling drained and too unwell to go about your normal routine.

Can Flu Get Better on Its Own?

Flu often clears up on its own, but it can make some people very unwell. That is why it is important to get vaccinated if you are advised to do so and to follow safe distancing to reduce the spread of infection.

Flu Symptoms 2025

As per NHS, below are the flu symptoms that people need to take care of:

• A sudden high temperature
• An aching body
• Feeling tired or exhausted
• A dry cough
• A sore throat
• A headache
• Difficulty sleeping
• Loss of appetite
• Diarrhoea or tummy pain
• Feeling sick and being sick

What Are The Symptoms Of A Cold?

• A blocked or runny nose
• Sneezing
• A sore throat
• A hoarse voice
• A cough
• Feeling tired and unwell
• A high temperature
• Aching muscles
• A loss of taste and smell
• A feeling of pressure in your ears and face

How Long Does a Cold Last?

In most cases, a cold can be managed at home without seeing a GP. You should start to feel better within one to two weeks, with symptoms developing over two to three days.

Cold Symptoms in Children: What Parents Should Know

Cold symptoms can last longer in young children. They may become more irritable, struggle with eating and sleeping, breathe through their mouth, and sometimes vomit after coughing. As per NHS, try to get enough rest over the Christmas holidays if possible, drink plenty of fluids, and eat nourishing food to help lower the risk of illness.