The COVID-19 pandemic may be over, but our immune systems are still feeling the impact. After years of battling constant viral threats, from COVID-19 to seasonal flu and other infections, our body’s defense system is exhausted. Many people continue to experience lingering inflammation, frequent illnesses, and slower recovery times. This extended state of immune stress has compromised us further to chronic illness, including autoimmune diseases and even neurodegenerative diseases such as Parkinson's. So why is our immune system still in trouble? And how do we give it its power back? Understanding immune exhaustion is the beginning of rebuilding our body's natural immunity.

A weakened immune system makes people more susceptible to disease, mental illnesses, and even sleep disorders. Now, new research indicates that immune system depletion may play an important role in the onset of Parkinson's disease, a degenerative neurologic disorder that compromises movement and cognition.

Role of Inflammation in Parkinson's Disease

Dysfunctional immune response is a leading cause of long-standing inflammation within the body, that has been found to contribute towards a multitude of conditions, including cardiovascular conditions, diabetes, depression, and neurodegenerative diseases such as Alzheimer's.

As people age, their immune system naturally becomes less effective. This deterioration, referred to as immune exhaustion, may be a key contributor to the onset and progression of Parkinson’s disease. Rebecca Wallings, a Parkinson’s Foundation Launch Award grant recipient and senior postdoctoral fellow at the University of Florida, believes that an accumulation of exhausted immune cells could be driving neurodegeneration in Parkinson’s patients.

How a Tired Immune System Might Affect Parkinson's?

Parkinson's disease is most commonly linked with the degeneration and loss of dopaminergic neurons—motor nerve cells that produce dopamine, an essential neurotransmitter for movement. While researchers have long suspected inflammation is involved in this neurodegeneration, the mechanisms are not yet well understood.

Wallings' study is on immune cell exhaustion, a process by which aging immune cells fail to control immune responses effectively. Her research indicates that instead of dampening inflammation in Parkinson's patients, attempts should be made to rejuvenate the immune system to regain its functionality.

Energy Deficiency in Immune Cells

One of the major findings of Wallings' work is the function of mitochondrial impairment in immune cell exhaustion. Mitochondria are commonly called the powerhouses of cells, as they are vital for generating energy. As mitochondria age and become inefficient, immune cells fail to function well, potentially accelerating neurodegeneration in Parkinson's disease.

Wallings has found that mutations in the LRRK2 gene, a recognized genetic risk factor for Parkinson's disease, are linked with defective mitochondrial function and immune cell exhaustion. Her current work includes testing various therapeutic approaches to restore mitochondrial function in immune cells with the potential to enhance the immune system and potentially prevent or treat Parkinson's disease.

Will Rejuvenating the Immune System Help in Treatment?

For decades, the standard practice in treating Parkinson's has been to suppress brain inflammation. Yet Wallings' work indicates that instead of slowing down immune responses, restoring the immune system could be a more successful strategy. By addressing mitochondrial impairment and immune resilience, researchers can potentially reverse or slow down Parkinson's disease.

Wallings is now looking into how to rejuvenate immune cells by fixing mitochondria. She studies immune cells from patients with Parkinson's as well as from healthy subjects and performs experiments on animal models to determine if rejuvenation of the immune system could result in improved disease outcomes.

Lifestyle Factors That May Affect Parkinson's Risk

While there is no cure for Parkinson's disease, some lifestyle adjustments may decrease the chances of developing the illness. Since neurodegenerative diseases are associated with chronic inflammation and immune dysfunction, developing habits that enhance immune function might prove helpful.

Diet: There is evidence to suggest that eating in accordance with the Mediterranean or MIND diets, both high in antioxidants, healthy fats, and anti-inflammatory foods, can encourage brain wellness and reduce Parkinson's risk.

Avoiding Dangerous Substances: Restricting alcohol and nicotine use can maintain a robust immune system and suppress inflammation.

Reducing Stress: Chronic stress weakens immune function, so methods such as meditation, exercise, and sufficient sleep can lead to improved overall well-being.

For years, the word "cancer" filled people with fear. Many still believe that a cancer diagnosis means the end. As an oncologist practicing in a Tier-2 city, I see every day that this is no longer true.

With early detection and modern treatment, cancer is now often curable. And the best part: you no longer need to travel to metros to get world-class care.

Why Early Detection Saves Lives

Cancer found early is cancer that can be treated easily.

- Breast cancer detected early has a survival rate of over 90%

- Cervical cancer can be prevented with a simple HPV vaccine and regular screening

- Oral, colon, lung, and prostate cancers also respond far better when caught before they spread

The problem: Most patients still come to us when symptoms become severe.

My request to you: Don’t wait. If there is a lump, persistent cough, bleeding, or unexplained weight loss for more than 2-3 weeks, please see a doctor. A 15-minute screening can add years to your life.

Also read: New Painless Brush Test Detects Oral Cancer In Just 60 Minutes With Over 90% Accuracy

Tier-2 Cities Are No Longer Behind

Earlier, patients from smaller cities had only two options: travel repeatedly to big metro hospitals or settle for limited local treatment. Both were exhausting.

That has changed.

Today, most Tier-2 cities now have comprehensive cancer centers with:

CT/MRI/PET scans, advanced pathology labs, chemotherapy daycare, radiation therapy, and experienced cancer surgeons.

This means diagnosis, surgery, chemotherapy, immunotherapy, and follow-up can all happen close to your home, with family support and at a lower cost.

Treatment Today Is Smarter, Not Just Stronger

Chemotherapy is still important, but it’s no longer the only option.

1. Targeted Therapy: Medicines that attack only cancer cells based on genetic testing. Fewer side effects.

2. Immunotherapy: Boosts your own immune system to fight cancer. Giving great results in lung cancer, kidney cancer, and blood cancers.

3. Advanced Radiation: Delivers precise radiation to the tumor while protecting healthy organs.

4. Minimally Invasive Surgery: Keyhole and robotic surgeries mean smaller cuts, less pain, faster recovery. Even elderly patients can now safely undergo surgery.

Also read: Cancer Kills Over 26,000 Daily; Cases to Hit 35 Million by 2050, Says WHO Report

Let’s Break 3 Dangerous Myths

Myth 1: "Cancer always causes pain in the beginning"

Fact: Most early cancers are painless. Don’t wait for pain.

Myth 2: "Surgery makes cancer spread"

Fact: This is false. Surgery is often the most curative treatment when done on time.

Myth 3: "Alternative therapies can cure cancer"

Fact: Diet, yoga, and wellness help with strength and side effects. But they cannot replace doctor-prescribed treatment. Delaying proven treatment reduces your chances of cure.

A Message Of Hope

A cancer diagnosis will change your life, but it does not have to end it. Across Tier-2 India, I am seeing patients go back to work, celebrate birthdays, and live full lives after cancer.

The key is 3 things: Awareness, Early Check-ups, and Trusting Modern Medicine. If you or a loved one has symptoms, please consult an oncologist early. Treatment closer to home is now possible, effective, and affordable. Cancer can be fought. And it can be won.

By Dr. Vikas Talreja, Oncologist, Regency Health, Kanpur

It's just July, and Mumbai’s monsoon has been swinging from tumultuous to alarmingly parched. When the climate shifts with such volatility, it’s bound to have an impact on your overall health.

From dehydration risk to chances of gastrointestinal infections, here’s how rapidly changing weather can take a toll on your mental health.

Impact Of Extreme Weather On Health

Respiratory Effects

HealthandMe spoke to Dr. Abizer Manked, Consultant Physician and Diabetologist at Saifee Hospital, Mumbai. One of the health impacts extreme weather has is on the respiratory system. Due to the increase of irritants and allergens, several respiratory issues can be triggered.

Dr Manked says, “The temperature and humidity can irritate our airways. This can trigger asthma, bronchitis, and allergies. It can also trigger coughing, giving us throat infections, and making it harder to breathe. This is especially true for people who already face breathing problems.”

Allergy Triggers

The expert says that allergy episodes increase significantly during the monsoon, especially when the rain is inconsistent. An increase in humidity paves the way for mould and fungi growth, which can make allergies worse.

Cold And Flu-Like Symptoms

When temperatures and humidity change rapidly, our immune response can take a hit. It can lead to frequent episodes of common cold, cough, and other flu-like symptoms.

“When the weather changes quickly, it can also make us more likely to get infections like the common cold and flu. The weather itself does not make us sick. The sudden change can affect our body’s ability to fight off infections. When we are indoors with a lot of people during the rain, viruses spread easily,” Dr Manked explains.

Also read: Delhi's Poor AQI, Monsoon Conditions Put Children's Lungs at Risk: Ways to Keep Kids Safe

Heat Exhaustion And Dehydration

When a heavy rain episode is followed by hot and humid weather, it can lead to increased risk of heat-related illnesses.

Dr Manked says, “The humidity makes it hard for our bodies to cool down. This can make us tired, give us headaches, and leave us dehydrated more frequently. It can even lead to heat exhaustion. This especially holds true for people who work outside or spend a lot of time in the sun.”

Viral And Parasite Infections

In the monsoon, Mumbai sees the highest number of cases of viral and parasite infections like dengue and malaria.

Flooding and waterlogging create breeding hotspots for mosquitoes, which can lead to more chances of infections. Poor hygiene and maintenance of surroundings further increase the risk.

Fungal Infections

Staying in damp clothes and shoes for long periods increases the risk of contracting fungal infections. The expert says it’s crucial to keep one’s clothes dry to avoid the riks of skin infections.

Also read: Allergic Rhinitis Affects 1 In 10 Indian Adults. Here's Why Monsoon Makes It Worse, And What Helps

How To Protect Yourself From Weather Changes?

Simple precautions can go a long way in reducing health risks during an irregular monsoon:

• Drink clean, safe water, and avoid consuming food exposed to floodwater.
• Wash hands regularly with soap, especially before eating.
• Avoid walking through floodwater whenever possible.
• Wear waterproof footwear if you must step into waterlogged areas.
• Keep homes dry and well-ventilated to reduce mold growth.
• Empty containers that collect rainwater to prevent mosquito breeding.
• Stay hydrated even if the weather feels cooler.
• Change out of wet clothes promptly and dry your feet thoroughly.
• Seek medical attention if you develop persistent fever, severe diarrhea, breathing difficulties, or symptoms after exposure to floodwater.

Children, older adults, and people with asthma, diabetes, high blood pressure, obesity, and other chronic illnesses are more likely to face these health effects during the monsoon. It is, therefore, crucial to take extra precautions and care for those with a weakened immune system.

When you hear the term plastic surgery, what comes to mind first? For many people, it's cosmetic enhancements such as facelifts, rhinoplasty, or body contouring. However, experts say this is one of the biggest misconceptions about the specialty.

Marking World Plastic Surgery Day on July 15, specialists highlighted that plastic surgery is far more than improving appearance. While cosmetic surgery focuses on enhancing aesthetics, reconstructive plastic surgery is dedicated to restoring form and function after injuries, burns, cancer, or congenital conditions.

Originally launched as National Plastic Surgery Day by the Association of Plastic Surgeons of India (APSI) in 2011, the observance was adopted globally by international plastic surgery societies in 2021.

The theme for World Plastic Surgery Day 2026 is "Changing Lives with Plastic and Reconstructive Surgery."

Plastic Surgery and Cosmetic Surgery Are Not the Same

Speaking to HealthandMe, Dr. Deepak K. L. Gowda, Senior Consultant – Aesthetics, Plastic Surgery & Reconstructive Surgery at SPARSH Hospital, said plastic surgery is a broad medical specialty, while cosmetic surgery is only one of its subspecialties.

Cosmetic surgery is performed to improve the appearance of otherwise healthy and functional body structures. Reconstructive plastic surgery, on the other hand, aims to restore appearance and function following injury, disease, cancer surgery, burns, or congenital defects.

According to Dr. Gowda, reconstructive procedures account for more than 75% of plastic surgery practice, while cosmetic procedures make up a comparatively smaller proportion. However, the growing popularity of aesthetic treatments has led many people to wrongly assume that plastic surgery is only about beauty enhancement.

Also read: Cyclosporiasis Outbreak: US Probes Taco Bell Link; CDC Reviews Over 5,100 Cases

Common Cosmetic Procedures

Cosmetic surgery is designed to enhance physical appearance in individuals whose body structures function normally. Some of the most commonly performed procedures include: breast augmentation, rhinoplasty (nose reshaping), facelifts

and dermal fillers and more.

When Is Reconstructive Plastic Surgery Needed?

Reconstructive plastic surgery helps restore both appearance and function after illness, injury, or trauma. Common procedures include:

• Breast reconstruction after cancer surgery
• Burn reconstruction
• Cleft lip and palate correction
• Reconstruction of congenital limb abnormalities
• Hand surgery

Read: Study Decodes Why COVID Survivors Continue To Suffer Vision Problems

Seven Questions To Ask Before A Cosmetic Procedure

Dr. Chintan Gujarati, Cosmetic and Plastic Surgeon at Ruby Hall Clinic, told HealthandMe that cosmetic procedures can enhance appearance and boost confidence, but they should always be approached with careful planning and informed decision-making.

He recommended asking these seven questions before undergoing any cosmetic procedure:

1. Is the procedure right for me?

Discuss whether the treatment is suitable for your health, goals, and individual needs.

2. Is my surgeon qualified?

Ensure the procedure is performed by a board-certified plastic surgeon or a trained specialist with relevant experience.

3. What are the risks?

Understand possible complications, including infection, scarring, or the need for additional treatment.

4. What results can I realistically expect?

Cosmetic procedures can improve appearance, but they cannot guarantee perfection.

5. What is the recovery process?

Ask about downtime, pain management, activity restrictions, and when you can safely return to your routine.

6. What will the procedure cost?

Request a detailed breakdown covering consultation fees, hospital charges, medications, and follow-up visits to avoid unexpected expenses.

7. What if I am unhappy with the results?

Discuss revision policies and available corrective options before making a decision.

Making an Informed Decision

Experts emphasized that choosing to undergo a cosmetic procedure is a personal decision that should be based on realistic expectations, qualified medical advice, and a clear understanding of the benefits, risks, recovery process, and overall costs.

They also stress that plastic surgery extends well beyond aesthetics, with reconstructive surgery continuing to play a vital role in restoring both function and quality of life for patients affected by injury, disease, or congenital conditions.