A Blood Test For Irritable Bowel Syndrome Can Help Build A Better Diet

Updated Feb 28, 2025 | 02:00 AM IST

SummaryAllergies, food intolerances and many other conditions often restrict people to a certain diet. Often people try some foods to realize whether they can eat it or not and that can cause harm or discomfort to them even if it isn’t long term. But a new test may resolve the trial and removal method all together!
(Credit-Canva)

Diet plays a very important role when it comes to your health. There are many people who have to adhere to strict diets because of certain conditions they have. While the basic understanding that we need all kinds of foods to fulfill our body’s needs, sometimes these foods can also cause harm to your body. For example, lactose intolerant people cannot eat or consume any kind of dairy product as their bodies do not have the necessary compounds, known as lactose, to break down dairy foods. Similarly, there are many foods that may be ok for others to consume, but not for people who have digestive issues like IBS. But this new clinical trial may be able to help us know what food we can eat based on our blood test! The blood test, called inFoods IBS, looks for a special type of antibody in the blood. Antibodies are like tiny soldiers that our bodies make to fight off things that could make us sick.

IBS is a very common problem, affecting a large number of people. Many people know that what they eat can make their IBS symptoms worse, but it's often hard to figure out exactly which foods are the culprits. This is because everyone is different, and what triggers one person might not trigger another. Doctors hear from patients all the time, asking for help in determining which foods are causing their problems. So, finding a reliable way to pinpoint those foods is important. This test is attempting to provide that reliability.

How Does This Blood Test Work?

Basically, the test is looking for an antibody called IgG. When the gut reacts badly to a food, it makes more of this IgG antibody. The test checks for reactions to 18 common foods, like wheat, milk, and certain fruits. If the test finds high levels of the IgG antibody for a certain food, it means that food is likely causing problems. Therefore, the patient should try to remove that food from their diet.

Many people with IBS struggle to find relief from their stomach pain and discomfort. This new study looked at whether a special blood test could help. The idea was to see if the test could tell people which foods were making their IBS worse. The results were encouraging. When people changed their diets based on what the blood test showed, about 60% of them felt less stomach pain. This is better than the 42% who felt better when they just tried a general diet change. This shows that the blood test might be a useful tool for people with IBS to get real relief.

How Does This Personalized Nutrition Approach Work?

Many doctors suggest that people with IBS try elimination diets, where they cut out certain foods to see if their symptoms improve. However, these diets can be very hard to follow, because they often require people to cut out a lot of different foods. Doctors are always looking for ways to give patients care that's tailored to their specific needs. In the case of IBS, that means figuring out exactly which foods each person should avoid.

This blood test is a step in that direction. Experts are calling it a move towards "precision nutrition." This means that instead of giving everyone the same diet advice, doctors could use the blood test to create a personalized plan for each patient. While more research is needed, this test brings hope that doctors will soon be able to give much more precise dietary recommendations to those people that suffer from IBS. While this test is yet to be approved by FDA, it could be a world of comfort and ease for people who suffer with IBS.

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Oral Microbiome and Placental Growth: What Every Expecting Parent Should Know

Updated Mar 30, 2026 | 07:26 PM IST

SummaryDr. Hrishikesh Pai, Consultant Gynaecologist & IVF Specialist, Lilavati Hospital Mumbai and Fortis Hospitals Delhi & Chandigarh reveals how oral microbiome changes during pregnancy and when you should seek professional support
Oral Microbiome and Placental Growth: What Every Expecting Parent Should Know

The oral microbiome is the community of bacteria, fungi, and other microorganisms that naturally live in the mouth — on the teeth, gums, tongue, and cheeks. More than

700 species are known to exist, most of which are harmless and many beneficial.

However, problems arise when harmful bacteria outnumber protective ones, leading to gum inflammation or periodontal disease. During pregnancy, hormonal changes increase blood flow to the gums and alter immune responses. As a result, many women notice bleeding, swelling, or sensitivity in the gums — a condition known as pregnancy gingivitis.

This is common and reflects physiological changes rather than poor hygiene.

The Mouth's Connection To The Placenta

Pregnancy is a systemic state in which the immune system, circulation, and inflammation are closely interconnected. Chronic gum inflammation can release inflammatory mediators into the bloodstream.

In research settings, certain oral bacteria have also been detected in placental tissues from complicated pregnancies. This suggests a biological link between oral health and

placental function, although the exact pathways are still being studied.

Importantly, this relationship reflects association rather than direct causation.

Why Does Placental Health Matter?

The placenta is an active organ that regulates oxygen and nutrient transfer, hormone production, and immune protection for the developing baby.

Healthy placental development supports:

  • Efficient oxygen and nutrient delivery
  • Balanced hormone production
  • Protection against infections
  • Steady fetal growth
Placental circulation increases significantly as pregnancy progresses, making it sensitive to systemic inflammation anywhere in the body — including the gums.

What Changes In Oral Health Are Normal During Pregnancy?

Up to 60–75 percent of pregnant women experience some degree of gum inflammation. Common changes include:

  • Bleeding while brushing
  • Swollen or tender gums
  • Increased plaque buildup
  • Persistent bad breath
Mild symptoms are common and manageable. However, persistent pain, loose teeth, or severe bleeding should not be ignored.

Can Oral Health Really Affect Pregnancy Outcomes?

Research from India and globally shows associations between periodontal disease and higher risks of preterm birth, low birth weight, and preeclampsia. Meta-analyses

suggest a modest increase in risk (around 1.5–2 times).

However, pregnancy complications are multifactorial. Oral disease alone does not directly cause these outcomes. Genetics, nutrition, metabolic health, and placental

biology all play important roles.

Treating gum disease improves oral health and reduces inflammation, though studies show mixed evidence on whether it directly lowers preterm birth risk. The goal is

prevention, awareness, and overall maternal health.

How Do You Support Healthy Oral Microbiome During Pregnancy?

Daily oral care:

  • Brush twice daily with gentle pressure
  • Use a soft-bristled toothbrush
  • Clean between teeth once daily
  • Rinse your mouth after vomiting to protect enamel
Nutrition support:

  • Calcium-rich foods like curd and ragi support dental health
  • Vitamin C from amla, guava, and citrus helps gum healing
  • Fibre-rich foods support saliva flow and microbial balance
  • Hydration and lifestyle
  • Drink adequate water
  • Limit frequent sugary snacks
  • Avoid tobacco in all forms
What emotional and social factors should you consider?

Pregnancy already carries emotional and physical changes, and dental symptoms can add anxiety. Support from partners and family members helps reduce mental load.

Stress can influence immunity and inflammation. Adequate rest, gentle activity such as walking or prenatal yoga, and open communication with healthcare providers

support both oral and overall health.

Warning Signs: When Should You Contact A Doctor Or Dentist?

Seek professional advice if you notice:

  • Severe tooth pain or swelling
  • Pus, fever, or difficulty chewing
  • Bad breath that does not improve
  • Persistent gum bleeding for two weeks

Pregnancy is a time when different systems of the body work in close coordination. Oral health, immune balance, and placental function are part of the same continuum.

Gentle attention to gum health is not about perfection. It is about creating supportive conditions for a healthy pregnancy and a healthy baby.

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Can Hormonal Imbalances Increase Endometrial Cancer Risk?

Updated Mar 30, 2026 | 07:00 PM IST

SummaryWomen's health is highly sensitive to hormonal changes. While an imbalance between oestrogen and progesterone can lead to complications in reproductive health, over time it can also spike cancer risk.
Hormonal imbalances

Hormonal imbalances can adversely affect women's health overtime. (Photo credit: iStock)

Hormonal imbalance plays an important role in the development of endometrial cancer, which is one of the most common types of gynaecological cancers worldwide. The endometrium is the inner lining of the uterus and is highly sensitive to hormonal changes, particularly the balance between oestrogen and progesterone. When the body is exposed to excess oestrogen without adequate progesterone, the endometrial lining grows excessively. Over time, this prolonged stimulation leads to abnormal cell changes and increases the risk of developing endometrial cancer or uterine cancer.

How does lifestyle affect hormones?

Dr Fahad Afzal, Consultant Oncologist at Saifee Hospital, while talking about the impact of lifestyle on hormones, said, “Several lifestyle and health conditions can contribute to this hormonal imbalance. Obesity is one of the most significant risk factors because excess body fat increases oestrogen production. Women who are obese therefore have higher levels of oestrogen, which stimulates the uterine lining. Moreover, conditions like PCOS, diabetes, and metabolic syndrome are also associated with hormonal disturbances that elevate the risk.”

A sedentary lifestyle and an unhealthy diet further worsen hormonal imbalance and inflammation in the body. Additionally, irregular menstrual cycles, early onset of menstruation, late menopause, and not having children increase lifetime oestrogen exposure.

Read more: Oncologists Warns Of The Cancer Rising Among Women in India

How to treat hormonal imbalances?

The encouraging aspect is that several of these risk factors are modifiable. Maintaining a healthy body weight, engaging in regular physical activity, and following a balanced diet help regulate these hormones and reduce the risks. Managing conditions like PCOS and diabetes with guidance from a trained medical professional is also important.

Equally important is awareness of symptoms. Any abnormal uterine bleeding or vaginal bleeding, especially after menopause, should never be ignored and requires prompt medical evaluation. Early detection of endometrial cancer often leads to good outcomes. Understanding the relationship between lifestyle, hormone balance, and cancer risk can help women take proactive steps towards prevention and timely diagnosis.

Women's health

What is the impact of hormones on endometrial cancer?

Dr Smit Sheth, cancer physician at M|O|C Mulund, said, “Hormones play a crucial role in a woman’s reproductive health, but when they fall out of balance, they can also increase the risk of certain cancers, including endometrial cancer. Endometrial cancer, which affects the lining of the uterus, is one of the most common gynaecological cancers in India. According to World Health Organization data, its incidence is steadily rising, particularly in urban populations where lifestyle changes are more pronounced.”

At the core of this risk lies an imbalance between two key hormones: oestrogen and progesterone. When oestrogen levels remain high without adequate progesterone to counteract it, the uterine lining can grow excessively, increasing the chance of abnormal cell changes over time. Modern lifestyle factors are significantly contributing to this imbalance. Rising obesity rates, sedentary habits, delayed pregnancies, and conditions like polycystic ovary syndrome (PCOS) are increasingly common among Indian women.

Fat tissue itself produces oestrogen, meaning overweight women often have higher circulating levels of this hormone. Studies suggest that obese women may have up to 2–4 times higher risk of developing endometrial cancer compared to those with a healthy weight. Additionally, irregular menstrual cycles, early onset of menstruation, and late menopause further extend lifetime oestrogen exposure, compounding the risk.

“Lifestyle today is a major driver of hormonal imbalance,” explains Dr Smit Sheth, cancer physician at M|O|C Mulund. “Obesity, lack of physical activity, and unmanaged metabolic conditions can silently increase oestrogen levels. Over time, this creates a favourable environment for endometrial cancer to develop, especially if symptoms like abnormal bleeding are ignored.”

Read more: Think Your Hormones Are Out Of Balance? Doctors Reveal The Warning Signs You Shouldn’t Ignore

Can endometrial cancer be detected in time?

The good news is that endometrial cancer is often detectable early. Warning signs such as postmenopausal bleeding, irregular periods, or unusual discharge should never be overlooked. Simple lifestyle changes, maintaining a healthy weight, regular exercise, a balanced diet, and timely medical check-ups can significantly reduce risk. In a country like India, where awareness remains limited, early education and proactive health behaviour are key to prevention.

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Abdominal Obesity Greater Risk Factor For Indians, says Dr. Jitendra Singh

Updated Mar 30, 2026 | 10:36 AM IST

SummaryAmid a rapidly growing number of chronic conditions, such as diabetes, hypertension, and cardiovascular diseases, the Minister shared that abdominal obesity is the driving factor.
Abdominal Obesity Greater Risk Factor For Indians, says Dr. Jitendra Singh

Credit: PIB

Abdominal, also known as central obesity, poses a greater health risk than overall obesity, especially in Indians, said Dr. Jitendra Singh, the Union Minister of State (Independent Charge) for Science and Technology.

Speaking at the release of a cardiology textbook titled “Advances in Obesity and Lipid Management in CVD,” by eminent cardiologist Dr. H.K. Chopra, Singh said that even lean and thin-looking individuals often carry significant visceral fat.

Amid a rapidly growing number of chronic conditions, such as diabetes, hypertension, and cardiovascular diseases, the Minister shared that abdominal obesity is the driving factor.

"There is sufficient evidence to show that Central obesity, even in apparently non-obese individuals, predisposes to a wide spectrum of metabolic disorders including diabetes, hypertension, cardiovascular diseases, fatty liver, dyslipidemia, etc.,” Singh, who is also a diabetologist, said.

“In other words, Abdominal or Central obesity is a greater risk factor compared to overall obesity, particularly in the Indian context where even lean and thin-looking individuals often carry significant visceral fat,” he added.

The Minister reiterated the importance of balanced health practices and emphasized the need for following a “sustained lifestyle discipline, adequate sleep, and scientifically guided preventive care”.

What Is Abdominal Obesity?

Abdominal obesity refers to an excessive accumulation of visceral fat around the stomach and internal organs, such as the liver, heart, kidneys, and the mesentery of the intestine.

Unlike subcutaneous fat, which lies beneath the skin, visceral fat is metabolically active and poses greater health risks.

It can increase your risk of heart disease, type 2 diabetes, high blood pressure, stroke, and some types of cancer.

Abdominal Obesity Greater Risk Factor For Indians, says Dr. Jitendra Singh

It is because visceral fat produces hormones and other substances that can cause inflammation and insulin resistance, which can lead to these health problems.

A 2024 study from the Washington University School of Medicine in St. Louis, Missouri, showed that a higher level of visceral fat was related to increased amyloid -- accounting for 77 per cent of the effect of high BMI on amyloid accumulation.

Who Is More At Risk Of Abdominal Obesity

The Minister said that while overall obesity is rising among both men and women, the prevalence of abdominal obesity remains disproportionately high and acts as an independent determinant of cardiometabolic risk. The presence of visceral fat around the abdomen, even without generalized obesity, has significant clinical implications and requires early detection and targeted intervention.

A waist circumference of more than 40 inches for men or 35 inches for women may indicate a higher risk of visceral fat accumulation.

While people with a larger waistline or pot belly are at known risk of having visceral fat, thin people too can have fat accumulation in their internal organs.

According to health experts, even people with a healthy weight can have high levels of visceral fat.

This is because visceral fat is not always visible on the outside of the body, and it can accumulate even if a person appears to be thin or in good shape.

Also read: Checking BMI For Body Weight? It Can Wrongly Mark You As Overweight or Obese, Says Study

Strategies for Successful Weight Management

To tackle obesity, one needs a holistic strategy beyond mere weight reduction. Healthy and sustainable weight reduction and improvement of health are more about body composition than mere weight. Major strategies are:

A balanced diet composed of whole foods, lean meats, and good fats in addition to physical exercise encourages sustainable weight reduction.

Resistance training helps in preserving muscle mass along with fat reduction, which improves metabolic well-being.

Prescription weight-loss medication can help manage obesity alongside lifestyle changes.

For people with severe obesity, surgeries such as gastric bypass or sleeve gastrectomy may provide significant long-term advantages.

Prioritize your metabolic health through healthy eating, portion control, and mindful eating for long-term success.

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