A Blood Test For Irritable Bowel Syndrome Can Help Build A Better Diet

Updated Feb 28, 2025 | 02:00 AM IST

SummaryAllergies, food intolerances and many other conditions often restrict people to a certain diet. Often people try some foods to realize whether they can eat it or not and that can cause harm or discomfort to them even if it isn’t long term. But a new test may resolve the trial and removal method all together!
(Credit-Canva)

Diet plays a very important role when it comes to your health. There are many people who have to adhere to strict diets because of certain conditions they have. While the basic understanding that we need all kinds of foods to fulfill our body’s needs, sometimes these foods can also cause harm to your body. For example, lactose intolerant people cannot eat or consume any kind of dairy product as their bodies do not have the necessary compounds, known as lactose, to break down dairy foods. Similarly, there are many foods that may be ok for others to consume, but not for people who have digestive issues like IBS. But this new clinical trial may be able to help us know what food we can eat based on our blood test! The blood test, called inFoods IBS, looks for a special type of antibody in the blood. Antibodies are like tiny soldiers that our bodies make to fight off things that could make us sick.

IBS is a very common problem, affecting a large number of people. Many people know that what they eat can make their IBS symptoms worse, but it's often hard to figure out exactly which foods are the culprits. This is because everyone is different, and what triggers one person might not trigger another. Doctors hear from patients all the time, asking for help in determining which foods are causing their problems. So, finding a reliable way to pinpoint those foods is important. This test is attempting to provide that reliability.

How Does This Blood Test Work?

Basically, the test is looking for an antibody called IgG. When the gut reacts badly to a food, it makes more of this IgG antibody. The test checks for reactions to 18 common foods, like wheat, milk, and certain fruits. If the test finds high levels of the IgG antibody for a certain food, it means that food is likely causing problems. Therefore, the patient should try to remove that food from their diet.

Many people with IBS struggle to find relief from their stomach pain and discomfort. This new study looked at whether a special blood test could help. The idea was to see if the test could tell people which foods were making their IBS worse. The results were encouraging. When people changed their diets based on what the blood test showed, about 60% of them felt less stomach pain. This is better than the 42% who felt better when they just tried a general diet change. This shows that the blood test might be a useful tool for people with IBS to get real relief.

How Does This Personalized Nutrition Approach Work?

Many doctors suggest that people with IBS try elimination diets, where they cut out certain foods to see if their symptoms improve. However, these diets can be very hard to follow, because they often require people to cut out a lot of different foods. Doctors are always looking for ways to give patients care that's tailored to their specific needs. In the case of IBS, that means figuring out exactly which foods each person should avoid.

This blood test is a step in that direction. Experts are calling it a move towards "precision nutrition." This means that instead of giving everyone the same diet advice, doctors could use the blood test to create a personalized plan for each patient. While more research is needed, this test brings hope that doctors will soon be able to give much more precise dietary recommendations to those people that suffer from IBS. While this test is yet to be approved by FDA, it could be a world of comfort and ease for people who suffer with IBS.

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The Silent Gene: Why Thalassemia Testing Before Pregnancy Matters

Updated May 23, 2026 | 09:00 PM IST

SummaryParenthood planning today is not only about financial preparation or healthy lifestyle changes, but also about understanding genetic health risks that can impact the child’s future.
The Silent Gene: Why Thalassemia Testing Before Pregnancy Matters

Credit: AI generated image

Many people carry the thalassemia gene without knowing it because they may not have any symptoms. A simple carrier screening test before pregnancy can help couples understand risks and make informed decisions while planning parenthood.

Importance of Genetic Screening

Parenthood planning today is not only about financial preparation or healthy lifestyle changes, but also about understanding genetic health risks that can impact the child’s future. And one such condition that tends to go unnoticed is thalassemia carrier status.

Did you know? Many individuals discover they are carriers only after facing difficulties during pregnancy or after the birth of a child with thalassemia major.

What Is Thalassemia?

Thalassemia is an inherited blood disorder that affects the production of hemoglobin, the protein in red blood cells that carries oxygen throughout the body. People who are carriers usually live normal and healthy lives and may not experience major symptoms. Because of this, many remain unaware of their carrier status for years.

However, it becomes a matter of concern when both partners are carriers of the thalassemia gene. In such cases, there is a huge risk that the child may inherit thalassemia major, a severe condition that may require lifelong blood transfusions, regular hospital visits, medications, and continuous medical care.

Why Thalassemia Often Goes Undetected

These are some of the challenges faced by families: So, challenges are that the thalassemia carrier status is often detected very late. Mild tiredness or anemia may be ignored or mistaken for iron deficiency, and many will not seek help.

So, couples do not consider genetic testing before marriage or pregnancy because they feel healthy and have no family history of the disease. When a child is born with thalassemia major, families may face stress, anxiety, repeated hospital visits, financial burden, and long-term treatment responsibilities. The condition can also affect the child’s growth, immunity, and overall quality of life.

The Need For Awareness And Early Action

This is why screening is important for couples: Carrier screening is a simple blood test that helps identify whether a person carries the thalassemia gene. If one partner tests positive, the other partner is advised to get tested as well.

Early screening before pregnancy helps couples understand their risks and explore available options with proper guidance. Thalassemia carrier screening is a small step that can make a major difference in parenthood planning.

Increasing awareness and encouraging timely testing can help families make informed decisions and reduce the burden of severe thalassemia in future generations. So, it is imperative to go for timely screening as advised by the expert and improve the quality of life.

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Doctors Must Speak More Openly About Their Mental Health, Says LiverDoc

Updated May 23, 2026 | 05:00 PM IST

SummaryLiver Doc stressed that addressing doctors’ mental health is as important as treating patients’ mental health. He also urged the medical community and regulatory authorities to introduce more interventions and support systems to prevent burnout and mental health disorders among doctors.
Doctors Must Speak More Openly About Mental Health, Says LiverDoc

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Mental health issues among doctors remain a serious but rarely discussed concern within the medical community, said Dr. Cyriac Abby Philips, popularly known on social media as the LiverDoc.

In an exclusive interaction with HealthandMe, the noted hepatologist highlighted the rising cases of burnout, depression, and suicide among healthcare professionals and the urgent need to address them.

He stated that doctors are among the major communities affected by mental health disorders, although the topic is often ignored within the profession.

“We have had very senior doctors die by suicide because of burnout,” he said, citing incidents involving highly successful doctors recently reported from parts of India, including Kerala.

Mental Health Of Doctors Impacts Patient Care

Liver Doc stressed that addressing doctors’ mental health is as important as treating patients’ mental health.

“A doctor who has good mental health will be a much better ally for the patient when it comes to treatment,” he said.

He also urged the medical community and regulatory authorities to introduce more interventions and support systems to prevent burnout and mental health disorders among doctors.

According to him, the emotional burden of treating critically ill patients and witnessing deaths regularly can deeply affect healthcare professionals.

“It’s depressing to treat patients and see them die. It’s depressing to see another human die,” he said.

The expert noted that doctors should find ways to openly discuss and process emotional stress and mental health struggles.

New Book On Burnout And Emotional Stress

Dr. Philips also addressed the issue in his recently released book, The Liver Doctor: Stories of Love, Loss and Regeneration.

He told HealthandMe that he has “very thoroughly and in very raw format addressed in the book” the mental health disorders affecting doctors, as it directly impacts patient care.

“Like every other doctor, I have also gone through that, and it's depressing to treat patients and see them die. I have this book to channelize that, and I feel less burdened when I do that, but other doctors also should find ways to do this. So this book also tells doctors to be more open about their mental health,” he said.

Deep Burnout Among Doctors

Doctors in teaching hospitals often endure long, unregulated shifts with little time for rest, especially during residency. Such exhausting work conditions not only increase the risk of medical errors but also significantly contribute to burnout, emotional exhaustion, and mental health problems among young doctors.

As per a recent nationwide survey on doctors’ mental health and morale, nine in ten doctors said they would not want their children to become physicians.

Also read: Global Mental Disorders Double In 33 Years, Affecting 1.2 Billion People: Study

The study, conducted by the Debabrata Mitalee Auro Foundation, surveyed 1,208 doctors across metropolitan cities and smaller towns over six months and found deep levels of burnout, fear of violence, and rising medico-legal anxiety among medical professionals.

Parliamentary Panel Flags Excessive Duty Hours

Further, the Parliamentary Standing Committee on Health and Family Welfare also raised concerns over “excessive continuous duty hours” for junior and senior resident doctors in April.

In its latest report, the panel warned that fatigue-driven errors and burnout could compromise care.

The Panel recommended that the government introduce and strictly enforce a formal “Clinical Duty Hours Regulation” policy. This would mandate fixed rest periods and monitored duty rosters, with oversight mechanisms to prevent violations.

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Can India Build The Next Generation Of CAR-T Therapies?

Updated May 23, 2026 | 12:00 PM IST

SummaryCAR-T therapies have transformed outcomes for several difficult-to-treat blood cancers globally. But despite strong initial responses, relapse remains one of the field’s biggest limitations.
Can India Build The Next Generation Of CAR-T Therapies?

Credit: iStock

India’s cell and gene therapy ecosystem is beginning to attract a different kind of attention that is driven not just by healthcare demand, but by proprietary science and platform-led innovation.

For investors, however, the larger story may not be the funding round itself. It may be the problem the company is trying to solve.

CAR-T therapies have transformed outcomes for several difficult-to-treat blood cancers globally. But despite strong initial responses, relapse remains one of the field’s biggest limitations. One reason is antigen escape, which means cancer cells can change the markers that therapies use to identify them, making them harder to detect over time.

In an analysis of 4,129 CAR-T treated patients, relapse remained a substantial issue after single-target therapy, with 42.1% of relapses associated with loss of the CD19 target itself. The finding points to a larger issue: precision may not be enough if therapies lose visibility over time.

The response increasingly appears to be a move toward multi-target and more durable platforms. A bispecific CAR-T platform designed to recognize more than one tumor marker, to reduce relapse is crucial.

The science itself is becoming increasingly platform-oriented. Beyond broader targeting, recent work explored why immune cells themselves lose effectiveness over time and identified pathways associated with stronger persistence and memory. While still early, the broader implication is that future therapies may need to be designed not only to attack disease, but also to remain active longer.

For India, that creates a larger opportunity. Historically, advanced therapies such as CAR-T have remained expensive and heavily dependent on technologies developed elsewhere. The aim is to significantly reduce treatment costs while building indigenous capabilities across design and manufacturing.

The shift matters because biotech investing is increasingly moving beyond services and generics toward intellectual property and platform science. The transition from bedside observations to translational platforms may be where the next phase of healthcare innovation and investment gets built.

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