A Blood Test For Irritable Bowel Syndrome Can Help Build A Better Diet

Updated Feb 28, 2025 | 02:00 AM IST

SummaryAllergies, food intolerances and many other conditions often restrict people to a certain diet. Often people try some foods to realize whether they can eat it or not and that can cause harm or discomfort to them even if it isn’t long term. But a new test may resolve the trial and removal method all together!
(Credit-Canva)

Diet plays a very important role when it comes to your health. There are many people who have to adhere to strict diets because of certain conditions they have. While the basic understanding that we need all kinds of foods to fulfill our body’s needs, sometimes these foods can also cause harm to your body. For example, lactose intolerant people cannot eat or consume any kind of dairy product as their bodies do not have the necessary compounds, known as lactose, to break down dairy foods. Similarly, there are many foods that may be ok for others to consume, but not for people who have digestive issues like IBS. But this new clinical trial may be able to help us know what food we can eat based on our blood test! The blood test, called inFoods IBS, looks for a special type of antibody in the blood. Antibodies are like tiny soldiers that our bodies make to fight off things that could make us sick.

IBS is a very common problem, affecting a large number of people. Many people know that what they eat can make their IBS symptoms worse, but it's often hard to figure out exactly which foods are the culprits. This is because everyone is different, and what triggers one person might not trigger another. Doctors hear from patients all the time, asking for help in determining which foods are causing their problems. So, finding a reliable way to pinpoint those foods is important. This test is attempting to provide that reliability.

How Does This Blood Test Work?

Basically, the test is looking for an antibody called IgG. When the gut reacts badly to a food, it makes more of this IgG antibody. The test checks for reactions to 18 common foods, like wheat, milk, and certain fruits. If the test finds high levels of the IgG antibody for a certain food, it means that food is likely causing problems. Therefore, the patient should try to remove that food from their diet.

Many people with IBS struggle to find relief from their stomach pain and discomfort. This new study looked at whether a special blood test could help. The idea was to see if the test could tell people which foods were making their IBS worse. The results were encouraging. When people changed their diets based on what the blood test showed, about 60% of them felt less stomach pain. This is better than the 42% who felt better when they just tried a general diet change. This shows that the blood test might be a useful tool for people with IBS to get real relief.

How Does This Personalized Nutrition Approach Work?

Many doctors suggest that people with IBS try elimination diets, where they cut out certain foods to see if their symptoms improve. However, these diets can be very hard to follow, because they often require people to cut out a lot of different foods. Doctors are always looking for ways to give patients care that's tailored to their specific needs. In the case of IBS, that means figuring out exactly which foods each person should avoid.

This blood test is a step in that direction. Experts are calling it a move towards "precision nutrition." This means that instead of giving everyone the same diet advice, doctors could use the blood test to create a personalized plan for each patient. While more research is needed, this test brings hope that doctors will soon be able to give much more precise dietary recommendations to those people that suffer from IBS. While this test is yet to be approved by FDA, it could be a world of comfort and ease for people who suffer with IBS.

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Low-Dose Aspirin Shows At Least 70% Lower Dementia Risk In Older Adults But A Serious Complication Still Remains

Updated Oct 26, 2026 | 07:00 PM IST

SummaryA recent study published in 'Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association' found that low-dose aspirin could be helpful in reducing dementia risk.
Aspirin Linked To 70% Lower Dementia Risk But A Serious Complication Still Remains

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Low-dose aspirin could play a key role in lowering the risk of dementia significantly in some older adults, according to a new genetic analysis. However, the benefit does not come without a complication: major bleeding.

The study, led by researchers at Monash University in Australia, is based on data from more than 13,500 participants in the ASPREE trial, which investigated the effects of low-dose aspirin in older adults. The study was published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.

Researchers found that the benefit was mostly seen among people with a specific genetic trait linked with platelet count.

70% Lower Dementia Risk Was Seen Among Older Adults

Also read: Aspirin & Colon Cancer: Lancet Study Explains Why It Could Help At An Earlier Stage But Not After Spread

Platelets are small blood components that help form clots and stop bleeding. Researchers have previously examined how aggregation of platelets might contribute to dementia, but the role of genetically influenced platelet counts still remains unclear.

The researchers examined genetic scores related to platelet count and compared dementia results among participants who were either assigned aspirin or placebo.

Among people in the highest 20% of platelet count genetic scores, dementia developed in 1% of those taking aspirin, compared with 3.3% of those receiving a placebo. This represented approximately a 70% lower risk.

Lead author Dr Peter Fransquet, a research fellow at Monash University's School of Public Health and Preventive Medicine, said, “Previous trials found aspirin didn't prevent dementia when everyone was considered together.”

“Our findings suggest there may be more to the story,” he said.

Risk Of Bleeding Increased

Also read: Trump Says He ‘Psychologically’ Needs To Pop Aspirin Every Day: But Is It Actually Safe?

The benefit was accompanied by a safety concern. Among participants in the same genetic subgroup, major bleeding occurred in 4.4% of those assigned to aspirin, compared to 2.1% of those given a placebo. That is a difference of 2.3 percentage points in both dementia cases and major bleeding events. In other words, the lower dementia rate cannot be considered in isolation from the increased bleeding risk.

Aspirin reduces the ability of platelets to form clots. This can be useful for certain people who need to take precaution against cardiovascular events, but it can also increase the risk of serious bleeding, including bleeding in the gastrointestinal tract or brain.

The study therefore does not prove that aspirin offers a favourable overall balance of benefits and harms for people with this genetic profile.

Could This Help Personalise Dementia Prevention?

The researchers found that the genetic signal was not linked to established genetic risk factors for Alzheimer's disease and dementia. Instead, it pointed towards platelet factor as a possible direction for further research.

“What's particularly interesting is that the signal wasn't linked to the established genetic risk factors for Alzheimer's disease and dementia,” Fransquet said. “Instead, it's pointing us towards platelet biology and gives us a new avenue to investigate.”

The findings could contribute to more personalised approaches to dementia prevention, in which treatments are tailored to characteristics that influence how individuals respond. But the results need to be replicated in other populations and tested in a clinical trial specifically designed for people with the identified genetic profile.

Fransquet said, “People shouldn’t start taking aspirin to prevent dementia on the basis of this study without consulting with their doctor, particularly given the increased risk of serious bleeding,” he said.

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Can Mental Health Improvement Help Lower High Blood Pressure? Study Points Towards 3 Habits

Updated Oct 26, 2026 | 03:16 PM IST

SummaryRecent research says that apart from lifestyle changes and medication, certain mental health habits can also help reduce blood pressure.
Can Mental Health Improvement Help Lower High Blood Pressure? Study Points Towards 3 Habits

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High blood pressure can be managed with medication and dietary changes. But recent research suggests that certain mental health habits can also help fight hypertension.

Mental health practices like mindfulness, optimism and gratitude may also support cardiovascular health, partly by helping people manage stress better and maintain healthier habits.

Hypertension affects nearly half of adults in the United States. While lifestyle changes like reducing salt intake, exercising regularly, maintaining a healthy weight and limiting alcohol remain crucial, the emerging study says that psychological wellbeing can also have a beneficial effect on blood pressure.

“Stress contributes to hypertension,” said Willie E. Lawrence Jr., a cardiologist and spokesperson for the American Heart Association. “It’s hard to get all the stress out of your life, but there are things that you can do to lower blood pressure, like mindfulness.”

According to the researchers, here are three mental health habits that may help:

Mindfulness

Also read: Long Term Air Pollution Exposure Linked With 14% Higher Dementia Risk: UK Study Based On 488,000 People

Mindfulness refers to paying attention to thoughts, emotions and physical sensations in the present moment without judging them. It may help alleviate stress and improve behaviours that affect blood pressure like dietary choices and physical activity.

Eric Loucks, professor of epidemiology and director of the Mindfulness Center at Brown University, developed a mindfulness-based blood pressure reduction programme that teaches participants all about self-awareness, attention control and emotional regulation. The programme teaches people to apply these skills to everyday decisions like choosing healthier foods.

“There can be energy that comes up to act on those insights,” Loucks said. “So if we decide we want to eat more healthily, can we be there with that energy in the grocery store, selecting the food for the week?”

Optimism

Also read: Eating A Handful Of Nuts Daily May Lower High Blood Pressure Risk, Study Finds

Optimism means expecting positive outcomes while recognising that challenges exist. Research has linked an optimistic outlook with better cardiovascular health, but evidence that it lowers blood pressure in people who already have hypertension is limited.

A study based on more than 100,000 active-duty US Army personnel without hypertension found that the most optimistic participants were less likely to develop high blood pressure during an average follow-up of three and a half years.

Julia Boehm, professor and chair of psychology at Chapman University said that practising optimism does not mean ignoring difficulties. Instead, people can identify realistic, achievable actions that support their health, such as choosing nutritious meals or becoming more physically active.

“This might mean something concrete like, ‘Am I going to choose to eat the salad or the french fries at lunch?’ and thinking optimistically that my choices in any given moment are going to translate into measurable effects in the long run,” Boehm said.

Gratitude

Gratitude involves acknowledging the people, experiences and acts one appreciates. Some research suggests it may affect cardiovascular responses to stress.

One study found that writing a gratitude letter changed how systolic blood pressure responded during a stress test. Systolic pressure, the upper number in a blood pressure reading, measures pressure when the heart contracts.

Mindfulness, optimism and gratitude should complement established hypertension treatment, not replace it. Medication, regular physical activity, a balanced diet and screening remain essential.

As Boehm cautioned, “You can’t ignore the doctor’s advice to either take your medications or engage in physical activity or eat fruits and vegetables. It’s just one piece of a larger strategy to bolster health.”

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Can Ear Nerve Stimulation Help Lower High Blood Pressure? Scientists Test A New Approach

Updated Oct 26, 2026 | 09:00 PM IST

SummaryA new clinical trial led by Queen Mary University of London has tested a non-invasive device that stimulates nerves through the ear to help manage uncontrolled high blood pressure. While the overall results were not statistically significant, participants with more severe hypertension showed promising reductions, warranting further research.
Can New Nerve Stimulation Techniques Help Control High Blood Pressure?

Researchers are testing whether non-invasive nerve stimulation through the ear can help lower blood pressure in people whose hypertension remains uncontrolled despite medication. (Image Credits: iStock)

A small, non-invasive device that stimulates nerves through the ear has shown early promise for people whose blood pressure stays high despite medication, according to a new clinical trial led by researchers at Queen Mary University of London.

What the device does

The device uses a technique called transcutaneous autonomic neuromodulation, or tAN, which aims to influence the autonomic nervous system, the network of nerves that automatically controls functions like heart rate, digestion, and blood pressure, according to Queen Mary University of London. Developed by Afferent Medical Solutions, the handheld device uses two small clips placed on the tragus, the flap of cartilage just in front of the ear canal, to deliver mild electrical pulses. Patients can use it themselves at home without visiting a clinic.

How the trial worked

The trial, called SCRATCH-HTN and funded by the National Institute for Health and Care Research, enrolled 63 people with uncontrolled hypertension, all of whom were already taking at least one blood pressure medication but still had readings above recommended levels, per Queen Mary’s release. Participants were randomly split into two groups: one received active nerve stimulation, the other used a sham device as a comparison.

For the first two weeks, participants used their assigned device for 30 minutes daily. For the following ten weeks, that dropped to once a week.

Also Read: AstraZeneca Cancer Drug Lowers Death Risk By 42% In Advanced Stomach Cancer Trial

What the results showed

The treatment was safe and generally well tolerated, and most participants stuck to the prescribed schedule, suggesting it could work for regular home use, according to the findings published in Hypertension, a journal of the American Heart Association. Across the full study group, however, there was no statistically significant difference in blood pressure between the active stimulation group and the sham group.

There was one notable exception. Among participants who entered the trial with more severe hypertension, those receiving active stimulation showed a greater reduction in blood pressure compared to those on the sham device, per a prespecified subgroup analysis in the study.

What the lead researcher said

“This is an exciting, highly patient-acceptable technology that could ultimately provide a cheap, scalable solution for millions,” said Dr. Ajay Gupta, the trial’s chief investigator and a clinical reader at Queen Mary University of London, in the university’s press release. “Although the trial did not achieve significance across the broad unselected group, those with more severe hypertension exhibited a clear blood pressure reduction in the active group compared to sham.”

He added that the study “points towards important new research directions that could help us understand whether non-invasive neuromodulation can benefit particular groups of patients with uncontrolled hypertension.”

Why this matters

High blood pressure is a major driver of cardiovascular disease, raising the risk of heart attacks and strokes over time. While medication helps many patients, a significant number continue to have blood pressure above target even while on treatment, which is part of why researchers are exploring additional, non-drug approaches that could work alongside existing therapies.

What comes next

The researchers are clear that this is an early finding, not proof of an effective treatment. Because the subgroup result came from a relatively small trial, it will need to be confirmed in larger studies before any conclusions can be drawn about how well the device actually works, and for whom.

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