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The main cause of death globally is still heart disease. Heart attacks may occur suddenly without any warning signs. However, in the film industry, intense chest pain would be portrayed for a heart attack. In actuality, many patients have slight symptoms that go unnoticed until the time of their heart attack days or even weeks prior to that.
Heart attacks do not always announce themselves with dramatic chest pain. Often, they manifest in subtle, easy-to-dismiss ways. Recognizing these overlooked warning signs and taking proactive steps toward cardiovascular health can save lives. If you or someone you know experiences any of these symptoms, seeking immediate medical care is crucial. Prioritizing heart health today can help prevent life-threatening complications in the future.
1. Discomfort Pressure in the Chest
One of the earliest and most common warning signs of an impending heart attack is pressure, tightness, or fullness in the chest. This pain is not typically sharp and sudden, like most people associate with a heart attack, but it can be intermittent, coming in waves, and lasting for several minutes before fading away. According to the American Heart Association, this is one of the red flags when accompanied by exertion. If you have persistent chest pressure, you should call emergency services immediately.
2. Pain Radiating to Other Parts of the Body
The well-known symptom of chest pain can also manifest discomfort related to a heart attack as pain radiating to other parts of the body. It is not unusual for people experiencing this kind of heart attack to report feeling pain in the shoulders, arms, back, neck, and even jaw. The vagus nerve is one that connects the heart to the brain, abdomen, and neck. The pain may be referred to these regions. In case you experience a sudden, unexplained pain in these regions, especially when exercising, seek a doctor's opinion.
3. Dizziness and Lightheadedness
Feeling dizziness upon standing up quickly or missing a meal is common, but unexplained dizziness often with chest pain or shortness of breath is the first sign of heart attack. Sudden hypotension can seriously decrease the blood supply to the brain and cause dizziness. Dizziness that does not go away on its own should not be ignored.
4. Unexplained Fatigue
It often happens that excessive tiredness, particularly in a busy lifestyle, is considered trivial, but ongoing fatigue, mostly in women, is a predictor of heart failure. According to some studies, extreme fatigue often starts a month before a heart attack, primarily in women. This is simply because the heart cannot pump well enough, leaving insufficient oxygen available to muscles and organs. Consult a healthcare professional if you become increasingly tired over time, yet are getting all the rest in the world.
5. Nausea, Indigestion, or Stomach Pain
Digestive problems like nausea, vomiting, or indigestion are often mistaken for acid reflux or food poisoning. However, these symptoms can also indicate reduced blood flow to the digestive tract, a common precursor to heart attacks. If you experience gastrointestinal distress alongside other symptoms like dizziness or chest discomfort, it's important to seek medical advice immediately.
6. Cold Sweats and Excessive Perspiration
Without apparent reason, a heart attack might be signaled by sudden sweating without any exercise or hot weather conditions. The heart's inability to function properly creates the body's "fight or flight" reaction, which means excessive sweating will occur. Be aware of your body and never ignore a cold sweat, particularly if it coincides with other symptoms.
7. Heart palpitations or irregular heartbeat
A racing or irregular heartbeat can be a normal reaction to stress or caffeine consumption. However, regular or unprovoked heart palpitations may indicate that the heart is under duress. If the heart is not getting enough oxygen-rich blood, it can start to beat irregularly. If you experience palpitations along with dizziness, chest pain, or shortness of breath, you should see a doctor right away.
8. Shortness of Breath
If suddenly climbing stairs or performing other everyday activities becomes a problem, then there may be a heart issue. Shortness of breath usually occurs with heart conditions because the circulation is not adequate and less oxygen is provided to the lungs. This symptom can occur either with or without chest pain and is an important indicator of the presence of underlying heart disease. If you find yourself experiencing sudden unexplained breathlessness, then seek a healthcare provider as soon as possible.
Early detection of these symptoms and early intervention can help avoid a life-threatening heart attack. You should visit a doctor if you feel the following symptoms:
Although heart attacks may come out of nowhere, lifestyle plays an important role in reducing a patient's risk; here are some heart-healthy habits to consider:
Take on a Heart-Healthy Diet: Focus on consuming whole foods, lean proteins, healthy fats, and fiber-rich fruits and vegetables. Try to limit processed foods, saturated fats, and added sugars.
Stay Active: Engage in at least 30 minutes of moderate physical activity most days of the week to strengthen your heart and improve blood circulation.
Smoking. Smoking is probably the single largest risk factor for heart disease. If you are a smoker, quitting can easily be the single best thing you can do to improve your heart health.
Deal with Stress: Chronic stress leads to heart disease. Relaxed people through various relaxation techniques including yoga, meditation, and even deep breathing, have lesser stresses.
Regular health checks Monitor blood pressure, cholesterol levels, and blood sugar on a regular basis. The risk factors' early detection can help avoid serious complications.
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A study of more than 700 individuals found distinct differences in the mix of bacteria in the mouths and lungs of those with severe long COVID.
Published in the European Respiratory Journal, the study found that differences in the lung microbiome were linked to respiratory problems, cognitive difficulties and digestive symptoms associated with long COVID.
The findings may help researchers understand why some people develop long COVID and identify potential treatments, according to the team from the University of Dundee, UK.
"The microbiome is important to maintain health throughout the body, so it is a strong candidate for something that may contribute to long COVID,” said lead author Dr. Daniela Alferes de Lima Headley.
The observational study included 771 adults who had been hospitalized for COVID-19 between February 2020 and March 2021. Researchers grouped participants according to the severity of their ongoing health problems and symptoms.
The participants had an average age of 57.5 years, and 38.5% were women.
Six months after hospital discharge, researchers collected saliva samples to examine microbes in the mouth and sputum samples to study the lung microbiome. They used DNA sequencing to identify the microbes and analyze their diversity. Participants also completed questionnaires about their symptoms.
The results showed that people with very severe long COVID had distinct differences in their oral and lung microbiomes compared with those who had fewer ongoing symptoms.
Microbiome differences were also associated with:
Further, the changes associated with long COVID symptoms also included an increased abundance of bacteria that produce lactic acid. These changes were also linked to signs of inflammation in participants' blood samples.
James Chalmers, chair of respiratory research at the University of Dundee, said the greatest microbiome changes were found in people with the most severe symptoms five to six months after COVID-19.
"We also found that changes in the airway microbiome were linked not just to lung problems, but also to symptoms like brain fog and gut symptoms, suggesting the lung microbiome could have effects on health more broadly," he added.
However, the researchers do not yet know whether these microbiome differences existed before COVID-19 or developed after infection. The long-term effects of these changes also remain unknown.
Chalmers said more research is needed to understand what causes long COVID, which continues to affect many people worldwide.
Because the microbiome can be altered through interventions such as antibiotics and probiotics, understanding its role could help researchers explore potential treatment options.
What Is Long COVID?
Long COVID refers to new, returning or ongoing health problems that persist four or more weeks after the initial COVID-19 infection. Symptoms can last for months or even years.
Common symptoms include fatigue, brain fog, memory problems, difficulty concentrating and slowed thinking.
Research has also suggested that brain inflammation may persist even after the virus is no longer detectable.
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For some women with endometriosis, getting a diagnosis is only the beginning of a long struggle to access treatment and navigate management.
In Canada, long waitlists for specialist appointments are pushing patients to consider expensive surgery abroad, highlighting how delays in care can prolong pain and disrupt everyday life.
Noelle Menu, 37, from Calgary, said her symptoms intensified after she stopped taking birth control while trying to conceive at 26.
Years of pain, emergency room visits, surgery and delays in specialist care eventually led her and her husband to seek private treatment in Tijuana, Mexico.
After being told that waiting several years to see a specialist in Canada was possible, Menu said: “We can’t deal with it in Canada.”
The couple used their savings and went into debt to pay for treatment at EndoGlobal in Mexico. The total cost was approximately $35,000, including travel, accommodation and other expenses, according to CBC News.
Her experience highlights the delay in addressing endometriosis that can intensify debilitating symptoms.
Endometriosis is a chronic condition in which tissue similar to the lining of the uterus grows outside it, potentially affecting the ovaries, bowel, bladder and other areas. The resulting inflammation and scar tissue can cause severe menstrual cramps, persistent pelvic pain, painful sex, bowel or urinary symptoms and difficulties conceiving.
The World Health Organization estimates that endometriosis affects around 10% of reproductive-age women worldwide, or approximately 190 million people.
Diagnosis can be challenging because symptoms vary and may overlap with other conditions. There is no single definitive test that identifies every case. Doctors may use a detailed medical history, pelvic examination, ultrasound or MRI, with surgery sometimes needed to investigate or treat suspected disease.
The WHO estimates that diagnosis commonly takes between four and 12 years, leaving many patients managing symptoms without a clear explanation for prolonged periods.
Also read: Endometriosis: Repurposed Anti-Parasite Drug Shows Promise In Mouse Study
For patients with severe disease, waiting for specialist care can mean continuing to live with pain that interferes with work, relationships, sleep and fertility plans.
Another Canadian patient, identified in CBC's report as Papiernik, described discovering that endometriosis had infiltrated her colon after a colonoscopy detected a mass. She was referred for specialist care but faced further waits for an appointment and surgery.
“Living like this for two years was just not an option for me,” she said.
Canada's House of Commons health committee has identified gaps in endometriosis care, while the condition's economic impact includes lost productivity and healthcare costs. The issue is not simply whether treatment exists, but whether patients can access appropriate care before symptoms and complications become harder to manage.
Surgery can remove endometriosis lesions, adhesions and scar tissue, reducing pain and treating complications. However, it is not a guaranteed cure. Symptoms may persist or return, and treatment decisions depend on disease severity, the organs involved, fertility goals and previous treatment.
Hormonal medicines and pain management can also help control symptoms. Some patients benefit from a combination of medical treatment, surgery and ongoing follow-up.
Travelling abroad may offer faster access to specialist treatment, but it comes with financial costs and other challenges. Patients should consider the surgeon's experience, the facility's standards, the possibility of complications and arrangements for follow-up after returning home.
Credit: Vicky Titcomb
A routine heart scan helped doctors detect pancreatic cancer in a 72-year-old US woman before it was too late. Vicky Titcomb, a Cape Cod bookstore owner and great-grandmother, underwent the scan at Mass General Brigham in March 2025, before traveling to New York City to visit her son.
Although she felt healthy, the scan revealed an abnormality on her pancreas. Further testing confirmed pancreatic cancer, one of the deadliest forms of cancer, CBS News reported.
“I felt like my life just switched in that moment,” Titcomb said. “It was a very weird feeling.”
Titcomb had undergone treatment for breast cancer in 2012.
In 2025, she was diagnosed with stage 1 breast cancer as well as pancreatic cancer. Doctors also found a mass on her ovary, which proved benign after the ovary was removed.
Pancreatic cancer is often diagnosed after it has spread to other organs. Its five-year overall survival rate is 13%.
The American Association for Cancer Research noted in its 2026 Cancer Progress Report that pancreatic cancer survival rates have shown little improvement despite advances in cancer care.
Doctors at Mass General Brigham planned chemotherapy and radiation to shrink Titcomb’s pancreatic tumor before surgery.
“I was told the size of the (pancreatic) cancer was about the size of a grape. The goal, to me, was trying to make this cancer a raisin,” she said. “That's the way I visualized it.”
The plan was to perform a Whipple procedure, a complex operation that removes the head of the pancreas, part of the small intestine, the gallbladder and the bile duct. Only about one in five pancreatic cancer patients is eligible for this surgery.
Titcomb’s early diagnosis made the operation possible.
“If I had not had that scan when I did, the outcome would have been bad,” she said.
Titcomb began chemotherapy in June 2025, receiving eight doses over four months. She then underwent three weeks of radiation and additional chemotherapy.
Surgical oncologist Dr. Thomas Clancy said she tolerated the treatment “very well.” The therapy shrank the pancreatic tumor enough for surgery.
On November 4, Titcomb underwent surgery to treat her breast cancer. Just over two weeks later, Clancy performed a robotic Whipple procedure to remove the affected part of her pancreas and other structures.
The operation was successful, and Titcomb said she was walking that night. She returned home after several days in the hospital.
Although she was recovering well, Clancy recommended two more months of chemotherapy because pancreatic cancer can be aggressive.
“There was a lot going on,” Titcomb said. “I just tried to cope with the day-to-day.”
In March 2026, after further treatment, Clancy told Titcomb she had no evidence of cancer. She will continue to undergo scans every three months.
“She’s living her life. I generally tell patients at this point, ‘You’re done with therapy ... you go about your days,’” Clancy said. “The goal is to not be thinking about it all the time.”
Titcomb is returning to running her bookstore, which family members helped manage during her treatment. She is also spending time with her children, grandchildren and great-grandchildren, keeping in touch with those who live far away through photos, videos and phone calls.
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