Your skin tell a lot about your health. By just looking at someone's skin, one can tell if they are sick, unhappy, or completely healthy. This is because whatever happens inside, reflects on the outside, on your skin. But there are ways to take care of your skin otherwise and it always does not mean expensive products or complicated routine. A basic skincare regimen includes cleansing, moisturizing, and sunscreen. Beyond this, good food with enough nutrition, regular exercise, sufficient sleep and stress management too is the key.

Here's all you need to know about skincare:

Who all need skincare?

Despite what social media tells you, children do not need fancy skincare products. The best approach for them is, once they start approaching the pre-puberty time, they keep their skin clean and use a non-comedogenic moisturizer if necessary. For children with eczema or other skin conditions, following a doctor-recommended routine is important.

Fighting Acne

Everyone experience acne at some point, especially during puberty. The best hack is to use oil-free products like benzoyl peroxide that can help control breakouts. If acne are causing scars, it is best to first take advise from your doctor and only then apply something else. A treatment usually takes up three-months to finally show results, therefore before considering alternatives a three-month window must be given.

When Should you start using anti aging products?

Again, social media here tells you to use it as soon as possible. But did you know that using anti aging products early will not help prevent wrinkles? A simple routine with a good sunscreen is often the best approach. Those in their mid-to-late 20s may consider introducing a mild retinol product, but factors like sun exposure and individual skin needs play a role in determining the right time to start.

What Ingredients Work?

Certain ingredients have proven beneficial, these are:

• Retinol for skin renewal
• Sunscreen for preventing premature aging

There may be many trendy ingredients like hyaluronic acid, however, not necessarily does it penetrate the skin deeply, but instead it helps retain moisture on the surface. Expensive doesn’t always mean better—affordable products often work just as well.

Do's and Dont's

Be Cautious: It is important that you be cautious when you use new products. Before introducing a new product, always take a patch test, especially for sensitive skin. For instance, retinol should be used only in small amounts a few times a week to prevent dryness. However, if it creates irritation, you can reduce usage, or switch to a milder formation.

Popping Pimples: This could lead to scarring and worsen inflammation, this is when spot treatments with salicylic acid or benzoyl peroxide could help. Also consider using face wash.

Use Sunscreen: Remember, sunscreen is a skincare essential! It also reduces the risk of skin cancer and prevent sun-induced aging. It is always best to apply a sunscreen with an SPF 50+. Remember to always go for a cream over spray and reapply every two hours.

Moles: Keep an eye on your moles. Though, mostly they are harmless, but if the size, shape, or color changes, then you must go see a doctors. While most moles are harmless, some could turn into cancer.

Lifestyle Changes: What really does well for your skin is when you start eating a healthy diet, rich in whole foods, healthy fats and variety of plants. Moreover if you are smoking, it accelerates aging and reduces blood flow to skin. Thus make these changes to make your skin radiant.

The biological age of ovaries may be influenced by the environment surrounding the organs, rather than being an entirely irreversible process. A new experiment done on mice found that older ovaries became biologically younger after being transplanted into younger animals, restoring and extending their ability to support pregnancy.

The research, led by scientists at Harvard Medical School, body's environment may influence how quickly the ovaries age. The findings could help researchers investigate treatments aimed at preserving ovarian function and fertility for longer in women.

Older Ovaries Produced Healthy Offspring In Younger Mice

The researchers transplanted ovaries from 13-month-old mice into younger mice that were four months old. The older donor mice had crossed their reproductive age.

Four to five months after transplantation, the younger recipients gave birth to healthy offspring, even though the transplanted ovaries were 17 to 18 months of age.

The same effect was not observed when older ovaries were transplanted into older recipients. This suggested that the recipient's biological environment, rather than the age of the ovaries alone, affected their reproductive function.

The team also performed the reverse experiment. When young ovaries were transplanted into older mice, the ovaries showed signs of accelerated ageing.

Also read: Heart Health In Women After Pregnancy: Why Pre-Eclampsia And Gestational Complications Matter Years Later

More About The Experiment

The researchers developed an ovarian ageing clock called OvaAge to observe the changes. The clock uses patterns of gene activity to ascertain an ovary's molecular age.

The results showed that the molecular age of older ovaries dropped when they were placed in younger animals. Conversely, young ovaries in older recipients aged faster.

The researchers also observed that older ovaries in younger hosts showed reduced inflammatory activity, while young ovaries in older hosts showed increased inflammation.

Also read: Children’s Mental Health In The Digital Age: Can Governments Protect Them Without Restricting Internet Access? | Interview

Effects Of Ovaries On Ageing Of Other Organs

The study also explored whether the ovaries affect ageing elsewhere in the body. When young ovaries were transplanted into older mice, researchers observed that the molecular ages of the brain, liver and uterus also dropped. The findings suggest that the ovaries may also influence other organs through hormones or other signals.

The researchers also identified changes in gene activity and cellular processes linked to inflammation, metabolism and tissue maintenance. Understanding these signals could help scientists investigate whether some effects of ovarian ageing can be targeted without an organ transplant.

Study's Scope In Women's Fertility

Ovarian ageing refers to a decline in both the number and quality of eggs. This reduces women's fertility as they grow older. The ovaries also produce hormones, including oestrogen, that affect overall health.

The new findings spark the possibility that the environment surrounding the ovaries could be a target for future treatments to preserve ovarian function.

If researchers can identify the signals that allowed older ovaries to function in younger mice, they may eventually be able to investigate ways to reproduce those effects without transplantation. But substantial research is still needed to move ahead.

The study was based mice, and ovarian biology, reproductive ageing and fertility outcomes differ significantly between mice and humans.

Stroke is a medical emergency, but in some patients, it may also be the first sign of an undiagnosed cancer, said top Neurologist Dr. Vinit Suri on World Stroke Day.

In an exclusive interview with HealthandMe for World Stroke Day, Dr. Suri, Senior Consultant Neurologist and Academic Coordinator at Indraprastha Apollo Hospital, New Delhi, explains the link between cancer and stroke, the warning signs that need urgent attention, and how patients can reduce their risk.

He noted that cancer and its treatment can also increase stroke risk, while a stroke may sometimes prompt doctors to investigate an underlying malignancy.

The noted expert also highlighted warning signs which may point to an underlying malignancy, and how cancer patients can reduce their risk and manage recovery.

How Are Cancer And Stroke Linked?

Also read: Recreational Drugs, Steroids & Birth Control: Expert Explains Why Strokes Are Arriving Decades Earlier

Dr Suri said cancer and stroke can overlap in three ways: cancer patients may have conventional risk factors such as hypertension and diabetes; cancer itself can increase blood clotting; and certain treatments can raise stroke risk.

“Cancer patients have double the risk of having a stroke compared to their age-matched individuals,” Dr Suri said.

He estimated that 10% to 15% of stroke patients may have cancer or cancer treatment as the underlying cause. Sometimes, a stroke is the first sign of an undiagnosed malignancy, known as a sentinel stroke. Thus, identifying the cause is important to prevent recurrent strokes.

Which Cancers Are Associated With Stroke?

Q. What Warning Signs May Point To An Undiagnosed Cancer?

Dr. Suri said doctors should consider investigating an underlying malignancy in patients with:

• Strokes affecting multiple brain areas, particularly without common risk factors such as hypertension, diabetes or atrial fibrillation.
• Recurrent strokes despite preventive treatment.
• Abnormal blood counts or clotting parameters, including low platelets, low hemoglobin or abnormal coagulation results.
• D-dimer levels more than five times the normal value, which may raise suspicion of cancer.

Investigations may include D-dimer testing, tumor markers such as prostate-specific antigen (PSA), other cancer biomarkers and whole-body PET-CT, said the noted neurologist.

A stroke may reveal cancer even without obvious cancer-related symptoms. Emergency stroke treatment must take priority, followed by investigations to identify the cause and prevent recurrence, he added.

Q. Which Stroke Symptoms Should Cancer Patients Never Ignore?

Read More: World Stroke Day: What Is BE FAST? Stroke Warning Signs To Watch For

Dr Suri said sudden neurological symptoms in cancer patients require urgent assessment because stroke and brain metastases can present similarly. Brain metastases may also cause seizures and one-sided weakness.

He recommended BE FAST to recognize possible stroke symptoms:

• B — Balance: Sudden loss of balance.
• E — Eyes: Sudden vision problems.
• F — Face: Facial asymmetry.
• A — Arms: Arm weakness or downward drift.
• S — Speech: Slurred speech or difficulty speaking.

Anyone experiencing these symptoms should seek emergency care, the expert said.

“Time is brain,” he said. Clot-dissolving drugs may be given within four and a half hours in eligible patients, while clot-removal procedures may be possible within six to 24 hours, depending on the patient.

CT scans may be sufficient in many cases, but MRI may help distinguish a stroke from brain metastases.

Q. How Can Cancer And Its Treatment Increase Stroke Risk?

Dr Suri said that some chemotherapy drugs and hormonal therapies for breast and prostate cancers can increase blood clotting.

Radiation to the neck may cause narrowing, scarring and fibrosis in the carotid arteries, potentially contributing to strokes years later.

READ: 1 in 7 Stroke Patients In India Are Under 45; Hypertension Leads Risk Factors: ICMR Study

Q. How Can Cancer Patients Reduce Their Stroke Risk?

Dr Suri advised people to control blood pressure, diabetes, abnormal cholesterol and obesity through physical activity and by avoiding a sedentary lifestyle.

Age, male sex and family history are the non-modifiable risks, while other risk factors include heart disease, smoking, alcohol use, chewing tobacco and drug abuse, which can contribute to strokes even in young people.

Dr Suri described hypertension as the most important modifiable risk factor and a major cause of ischemic and hemorrhagic strokes. He recommended regular blood pressure checks, reducing salt intake, walking and taking prescribed medication. He also stressed diabetes management and identifying atrial fibrillation, which can cause strokes affecting multiple brain blood vessel territories in older adults.

Oncologists should consider stroke risk when choosing treatments, particularly for patients with pancreatic or lung cancer and other adenocarcinomas associated with increased clotting risk, he said.

Treatment may involve addressing the underlying cancer through chemotherapy or surgery and preventing further clots. Warfarin may not work in some cases, and doctors may consider direct oral anticoagulants (DOACs) or low-molecular-weight heparin.

Q. How Do Cancer And Stroke Together Affect Recovery?

Dr Suri said having both conditions can worsen prognosis because stroke can cause death or long-term disability, while cancer may reduce life expectancy.

“When these two double whammies are happening together, the outlook becomes much, much graver,” he said, adding neurologists and oncologists must work together to adjust treatment.

“Both of them have to be involved together as a team to plan and modify both the cancer therapy as well as the stroke therapy,” he said.

Some medicines that increase stroke risk may need to be withdrawn. Blood thinners must be selected with the oncologist because certain chemotherapy drugs can rapidly lower platelet and white blood cell counts.

Cancer does not automatically prevent stroke rehabilitation, Suri said, although severe weakness or frailty may limit participation.

“Cancer is not likely to interfere with the rehabilitative processes unless and until it has made the patient very weak and frail,” he said.

Q. Can Cancer And Stroke Occur In Young People?

Yes, Dr Suri said. Both can occur at any age, although their causes and cancer types may differ across age groups.

“Stroke can occur even in very young children,” he said, noting that infants may have strokes due to arteriopathies and other conditions. Both conditions become more common with age, but neither has a lower age limit.

Ever since artificial intelligence became a part of our lives, we have fallen into the habit of quickly firing up that chat box and typing our biggest worries, darkest thoughts among many other things. But it has become important to stop and ponder whether AI is really producing the most useful and viable solutions for us.

A recent study published in NEJM AI suggests that artificial intelligence systems may recommend more expensive medical care than doctors. The findings said that AI-generated care plans may cost more than three times as much as doctors’ recommendations.

The researchers compared recommendations from 24 artificial intelligence systems with the recommendations by physicians across 200 outpatient and emergency department visits.

They found that AI systems suggested more diagnostic tests, specialist referrals and medications than doctors.

The average estimated cost of care recommended by 20 general-purpose AI systems was USD 314 per visit compared to USD 97 for physicians’ plans. That was equal to a 3.2-fold difference.

How Did Researchers Compare AI’s Recommendations With Doctors’?

The researchers used 200 de-identified patient history and notes from outpatient and emergency department visits, sourced from MTSamples, a public collection of clinical documentation.

They gave the notes to 24 AI systems, including 20 general-purpose large language models and four specialised medical AI systems. Each system produced an assessment and plan based on that information. Researchers then compared these recommendations with the original physician’s documented plan.

The researchers estimated costs using 2026 US Medicare rates. The cost comparison included diagnostic tests and specialist referrals. New medications were counted separately. The results showed that AI-generated plans recommended more investigations and specialist consultations, increasing the estimated cost of care.

Also read: Woman With Epilepsy Dies After Following ChatGPT’s Advice To Stop Medication: Why AI Cannot Replace A Doctor

AI Recommended More Tests Even When Doctors Ordered None

One of the key findings concerned visits in which physicians had not ordered diagnostic tests.

Doctors had recommended no diagnostic testing in approximately 66% of the encounters. Across these visits, the AI systems consistently suggested tests, often including standard panels of blood investigations.

Overall, diagnostic testing recommended by the general-purpose AI systems cost an estimated USD 176 per visit compared to USD 71 for doctors’ plans.

AI systems also recommended specialist referrals and new medications more frequently than doctors. The researchers saw an average of 1.14 new medications per visit across the AI systems, compared to 0.59 in physicians’ plans.

These findings suggest that AI-generated care plans may favour additional investigations and interventions.

Also read: AI Diet Advice Turns Dangerous: ChatGPT Plan Lands Man In ER With Bromide Poisoning

Can Changing Prompts Help Obtain Less Expensive Medical Care From AI?

The researchers also examined whether changing the prompts given to AI systems could reduce the cost of their recommendations.

Prompts containing savings and budget-friendly suggestions reduced the estimated cost difference, but did not eliminate it. The cost ratio fell from 3.2 times physicians’ plans to 2.5 times when systems were specifically instructed to recommend cost-friendly tests and medicines.

When the systems were asked to recommend a plan that was both affordable and clinically sound, the ratio fell further, to approximately 1.4 times the physicians’ cost.

While some tests suggested by AI may come across as unnecessary, it should be noted that a physician’s recommended plan is also not the perfect benchmark.

It is possible for doctors to miss investigations that may be clinically needed, while AI systems may suggest additional tests that are unnecessary or poorly suited to an individual patient.

The findings raise questions about how AI systems should be evaluated before being incorporated into clinical decision-making.

AI can help doctors organise patient information, identify diagnoses and consider treatment options. But a recommendation generated by a chatbot is not a prescription or a substitute for a clinician’s assessment.