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Stress is an inevitable part of life, but its consequences are not just mood swings and mental fatigue. Continual stress makes people produce extra cortisol, a hormone that has a critical role in adapting to short-term challenges, but chronically in high quantities it tends to cause harm to the body causing lots of physical and mental disorders.
The adrenal glands produce cortisol, which helps the body control its "fight, flight, or freeze" response. Cortisol temporarily adjusts blood sugar levels, maintains blood pressure, and assists the immune system, among other functions, in short spurts. But when stress persists, cortisol remains high, and necessary functions of the body are interfered with and rendered more susceptible to disease.
According to one survey conducted by the American Psychological Association, stress negatively affects a third of Americans' physical health. Concerns are reinforced by research where studies have shown 80% of primary care visits are stress-related.
But why does stress have such a profound impact? Elevated cortisol limits the immune system's ability to fight infections, disrupts hormonal balance, and triggers inflammation. Over time, these changes can lead to serious health complications.
Do you have involuntary eye spasms? These harmless but annoying twitches often indicate elevated cortisol. The tiny muscles around the eyes are extremely sensitive to stress, contracting or spasming because of cortisol's stimulant-like effects.
Your skin often reflects what is going on inside your body, and chronic stress can cause inflammatory skin conditions. Elevated cortisol levels stimulate oil production, which exacerbates acne. It also slows down the healing process, worsens conditions like eczema, and contributes to general irritation of the skin.
It also interferes with the body's balance of salt and water, which causes fluid retention and bloating. Excess cortisol also slows down blood flow to the digestive system, which further weakens gut bacteria and causes poor digestion, excess gas, and abdominal discomfort.
High cortisol stimulates the production of insulin, which can cause blood sugar to drop, making people want to eat sugary, high-fat foods. For many, this becomes an excuse to stress-eat and gain weight. For others, the opposite is true: their appetite disappears under stress, causing them to lose weight.
If you’re noticing random bruises, elevated cortisol could be the culprit. This hormone weakens skin proteins and the walls of small blood vessels, making your skin more fragile and prone to damage.
Do you feel rundown or experience muscle aches, fatigue, or upset stomach regularly? Elevated cortisol mimics cold-like symptoms. Long-term stress also weakens the immune system, making you more susceptible to infections.
Also Read: Stressed At Work? Your Sleep Might Be Paying The Price, New Study Shows
Chronic stress can damage your eyesight. Elevated cortisol disrupts blood flow to the eyes, increases eye pressure, and raises the risk of glaucoma. Symptoms like dry eyes, blurred vision, and light sensitivity are also common.
Irregular Menstrual Cycles that disrupt the menstrual period. In females, this leads to hormonal distress causing irregular or missed periods. Over time, it may also disturb fertility.
If you hear ringing, buzzing, or hissing sounds without an apparent source, stress might be the culprit. Cortisol affects the auditory system by interfering with blood flow and nerve function and could be the trigger for tinnitus.
Increased levels of cortisol contribute to inflammation that can exacerbate conditions such as arthritis and promote the development of heart disease. Chronic inflammation is also associated with mental health conditions, including anxiety and depression.
Left unchecked, high cortisol levels can lead to more than just short-term discomfort. Chronic stress has been associated with serious conditions such as heart disease, psychiatric disorders, and metabolic syndromes. A 2013 study published in JAMA Internal Medicine underlined the link between stress and physical health, with recent research in Neurobiology of Stres supporting these findings.
Managing stress and cortisol levels is essential for maintaining overall health. One effective approach is practicing mindfulness through meditation or yoga, which helps lower cortisol by calming the mind and promoting relaxation. Regular physical exercise, especially aerobic activities, helps reduce stress hormones and boosts endorphins. Prioritizing sleep is crucial, as lack of rest can increase cortisol levels; aim for 7-9 hours per night.
Another remedy is an overall balanced diet full of anti-inflammatory foods like fruits, vegetables, and whole grains that could manage cortisol production. Finally, it would prevent burnout and chronic stress if proper boundaries were set at work and in personal life.
Credits: Trondheim Sleep Group/St Olav's hospital
Lights will guide you home, but will it treat your mental illness? It could. According to new findings, changing the color of light could help treat mental illness. A psychiatric unit in Trondheim, Norway is testing how light could be used as a potential treatment for mental health conditions like psychosis and depression. The approach is simple, yet innovative that aims on changing the ward's design to help patients in their recovery. As night falls, filters are lowered over windows and lights are changed. This creates a soothing ambiance and eliminates the blue wavelengths that could disrupt body's internal clock.
The findings have been published in PLOS Medicine, that looked on the patients who were treated in the circadian-adapted ward. The study showed that these patients showed greater clinical improvement and less aggressive behavior. "Just by changing the light spectrum, we can improve the quality of treatment," said Havard Kallestad, a researcher at St Olavs hospital who led the study.
Researchers are now looking at its use for other healthcare areas, which means beyond the psychiatric wards. The UK's National Institute of Health and Care Research (NIHR) has also called for trials to see if this could "reset" the internal clocks of people who are living in care homes to reduce their behavioral disturbances, especially in dementia patients.
Professor Anthony Gordon of the NIHR said that it was about determining if light therapy could be used to reduce anxiety and improve sleep.
Read: Doctor Explains How Sleep Debt Is Becoming A Crisis In Urban Professionals
The psychiatric unit was divided in two identical halves with the same layout, staffing, and facilities. The key difference between the two was the evening light environment. One of the wards used blue-depleted lighting from 6pm onwards, where blinds and filters blocked similar light from windows and screens.
Whereas the other ward used standard hospital lighting and the unique design allowed researchers to study the impact of different lighting on patient recovery.
Circadian rhythm is the body's internal 24-hour clock that regulated the sleep-wake cycle, hormones, digestion, and temperature, which aligns them with day and light. It is primarily controlled by light-sensitive brain cells, or what people commonly call the 'body clock'.
Disruption in the cycle could link to various health issues, which includes mental health problems like depression and cardiovascular diseases. This is why the test in Trondheim could prove beneficial in treating patients across the spectrum of illness.
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Dialysis patients who took daily fish oil supplements had a 43 percent lower risk of major cardiovascular events, according to a large international clinical trial jointly led in Australia by Monash Health and the School of Clinical Sciences at Monash University.
Published in The New England Journal of Medicine, the study found that participants who took four grams of fish oil each day experienced significantly fewer major cardiovascular events, including heart attack, stroke, cardiac death and vascular-related amputations than those who received a placebo.
The supplement contained the omega-3 fatty acids EPA and DHA, which are naturally found in fish oil.
Adjunct Professor Kevan Polkinghorne, a nephrologist at Monash Health and adjunct in the School of Clinical Sciences, led the Australian portion of the trial said: "Patients on dialysis have extremely high cardiovascular risk, and very few therapies have been shown to reduce that risk," Professor Polkinghorne said. "In a field where many trials have been negative, this is a significant finding.
"Dialysis patients typically have much lower levels of EPA and DHA than the general population. This may help explain the magnitude of benefit observed in this group."
He also noted that results applied specifically to people undergoing haemodialysis for kidney failure and the findings should not be generalized to healthy individuals or to other groups of patients.
Omega-3 fatty acids are polyunsaturated fats known for their crucial role in brain function and overall mental health. Fish oil is particularly rich in EPA and DHA, which are vital components of cell membranes and have strong anti-inflammatory effects in the body.
These omega-3s play a critical role in human development, and they are primarily found in fatty fish and fish oil. Since many people do not consume enough fish, supplementation is often recommended to ensure adequate intake of these essential fatty acids.
Although the body can convert another type of omega-3, alpha-linolenic acid (ALA), into EPA and DHA, this process is not highly efficient. As a result, fish oil supplements may provide a convenient way to ensure optimal levels of omega-3s.
Some popular sources of Omega-3 include:
Earlier this month, Finance Minister Nirmala Sitharaman announced a surprising tax reduction for India's fishers and marine industry, and experts say it is good news for you too.
Until now, fish caught by Indian vessels beyond territorial waters and brought back to the country for mass consumption has been treated as import, attracting customs duties and integrated goods and services tax (GST).
The combined tax burden raises costs and compliance issues, which discouraged people from deep-sea and exclusive economic zone (EEZ) fishing as well as
However, during her Union Budget 2026 presentation, Sitharaman proposed that fish caught in the EEZ and high seas by Indian fishing vessels are treated as duty-free when brought into Indian ports and treated as exports when landed at foreign ports.
This means that the market availability for Omega-3 packed fishes including salmon, mackerel, tuna, herring and sardines will significantly increase as their existing steep prices see a tremendous fall.
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Malaria infected an estimated 282 million people and caused about 6,10,000 deaths worldwide in 2024, according to the World Health Organization’s (WHO) latest World Malaria Report. The report placed strong emphasis on drug resistance, warning that it remains one of the biggest threats to global elimination goals.
WHO-recommended vaccines helped prevent roughly 170 million cases and one million deaths last year, which is about nine million more than the year before. Around 95 per cent of malaria deaths occurred in the African Region, with children under five forming the largest share.
Within the WHO South-East Asia Region, India represented 73.3 per cent of all malaria cases and 88.7 per cent of all malaria-related deaths. The report also underscored that the world is nowhere close to meeting the targets set under the Global Technical Strategy for malaria 2016–2030.
However, a group of University of Nottingham researchers have now found a key protein that is an enticing target for new antimalarial interventions. The study looked at a protein called Aurora-related kinase 1 (ARK1), which plays an important role in the parasite’s unusual cell division.
ARK1 helps control the parasite’s mitosis (cell division) and organizes a structure called the spindle, which separates genetic material so new parasites can form.
Scientists turned off the ARK1 gene using genetic engineering techniques to see what would happen. Without ARK1, the parasites could not form proper spindles and failed to reproduce, suggesting the protein could be a weak spot that future malaria treatment.
"What makes this discovery so exciting is that the malaria parasite's 'Aurora' complex is very different from the version found in human cells," senior author Rita Tewari said.
Anopheles stephensi is a malaria-transmitting mosquito originally found in South Asia. Unlike many other malaria vectors, it thrives in cities and breeds in man-made water sources such as storage tanks, containers, and discarded tyres. It can carry both Plasmodium falciparum and P. vivax parasites.
In recent years, this mosquito has spread into several African countries, where it adapts easily and shows resistance to multiple insecticides. This expansion has increased the threat of urban malaria outbreaks, as highlighted by the World Health Organization.
At present, Anopheles stephensi has been detected in nine African countries and is proving difficult to control due to widespread insecticide resistance.
The report noted that WHO approved the world’s first malaria vaccines in 2021, and 24 countries have now added them to their regular immunisation schedules. Dr Tedros Adhanom Ghebreyesus, WHO Director-General, said that new preventive tools provide reason for optimism, but many obstacles remain.
He pointed out the rise in cases and deaths, the pressure from drug resistance, and the impact of reduced funding. These factors could undermine the progress achieved over the last twenty years.
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