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Stress is an inevitable part of life, but its consequences are not just mood swings and mental fatigue. Continual stress makes people produce extra cortisol, a hormone that has a critical role in adapting to short-term challenges, but chronically in high quantities it tends to cause harm to the body causing lots of physical and mental disorders.
The adrenal glands produce cortisol, which helps the body control its "fight, flight, or freeze" response. Cortisol temporarily adjusts blood sugar levels, maintains blood pressure, and assists the immune system, among other functions, in short spurts. But when stress persists, cortisol remains high, and necessary functions of the body are interfered with and rendered more susceptible to disease.
According to one survey conducted by the American Psychological Association, stress negatively affects a third of Americans' physical health. Concerns are reinforced by research where studies have shown 80% of primary care visits are stress-related.
But why does stress have such a profound impact? Elevated cortisol limits the immune system's ability to fight infections, disrupts hormonal balance, and triggers inflammation. Over time, these changes can lead to serious health complications.
Do you have involuntary eye spasms? These harmless but annoying twitches often indicate elevated cortisol. The tiny muscles around the eyes are extremely sensitive to stress, contracting or spasming because of cortisol's stimulant-like effects.
Your skin often reflects what is going on inside your body, and chronic stress can cause inflammatory skin conditions. Elevated cortisol levels stimulate oil production, which exacerbates acne. It also slows down the healing process, worsens conditions like eczema, and contributes to general irritation of the skin.
It also interferes with the body's balance of salt and water, which causes fluid retention and bloating. Excess cortisol also slows down blood flow to the digestive system, which further weakens gut bacteria and causes poor digestion, excess gas, and abdominal discomfort.
High cortisol stimulates the production of insulin, which can cause blood sugar to drop, making people want to eat sugary, high-fat foods. For many, this becomes an excuse to stress-eat and gain weight. For others, the opposite is true: their appetite disappears under stress, causing them to lose weight.
If you’re noticing random bruises, elevated cortisol could be the culprit. This hormone weakens skin proteins and the walls of small blood vessels, making your skin more fragile and prone to damage.
Do you feel rundown or experience muscle aches, fatigue, or upset stomach regularly? Elevated cortisol mimics cold-like symptoms. Long-term stress also weakens the immune system, making you more susceptible to infections.
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Chronic stress can damage your eyesight. Elevated cortisol disrupts blood flow to the eyes, increases eye pressure, and raises the risk of glaucoma. Symptoms like dry eyes, blurred vision, and light sensitivity are also common.
Irregular Menstrual Cycles that disrupt the menstrual period. In females, this leads to hormonal distress causing irregular or missed periods. Over time, it may also disturb fertility.
If you hear ringing, buzzing, or hissing sounds without an apparent source, stress might be the culprit. Cortisol affects the auditory system by interfering with blood flow and nerve function and could be the trigger for tinnitus.
Increased levels of cortisol contribute to inflammation that can exacerbate conditions such as arthritis and promote the development of heart disease. Chronic inflammation is also associated with mental health conditions, including anxiety and depression.
Left unchecked, high cortisol levels can lead to more than just short-term discomfort. Chronic stress has been associated with serious conditions such as heart disease, psychiatric disorders, and metabolic syndromes. A 2013 study published in JAMA Internal Medicine underlined the link between stress and physical health, with recent research in Neurobiology of Stres supporting these findings.
Managing stress and cortisol levels is essential for maintaining overall health. One effective approach is practicing mindfulness through meditation or yoga, which helps lower cortisol by calming the mind and promoting relaxation. Regular physical exercise, especially aerobic activities, helps reduce stress hormones and boosts endorphins. Prioritizing sleep is crucial, as lack of rest can increase cortisol levels; aim for 7-9 hours per night.
Another remedy is an overall balanced diet full of anti-inflammatory foods like fruits, vegetables, and whole grains that could manage cortisol production. Finally, it would prevent burnout and chronic stress if proper boundaries were set at work and in personal life.
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A sudden bone fracture that seems out of proportion to the injury could sometimes signal an underlying life-threatening condition. Doctors say that while most fractures are caused by accidents or age-related bone weakness, certain cancers can damage bones and make them fragile enough to break with minimal force.
While this is still relatively uncommon compared to injuries or diseases such as osteoporosis, experts stress that unusual fractures should not be ignored.
Bones are living tissues that constantly rebuild and repair themselves however, some cancers can start directly in the bone which are known as primary bone cancers., such as osteosarcoma, Ewing’s sarcoma, and chondrosarcoma. These cancers damage bone structure and make it fragile.
However, more often the problem comes from cancers that begin in other organs and then spread to the bones, also known as metastasis, which means cancer cells travel from their original location to another part of the body.
According to Dr Rakesh Kr Agrawal, Senior Consultant and Head of Radiation Oncology at Andromeda Cancer Hospital in Sonipat, cancers such as breast, prostate, lung, kidney, and thyroid frequently spread to bones. The spine, pelvis, ribs, and thigh bones are particularly common sites.
When cancer spreads to these areas, it can destroy bone tissue or create weak spots, increasing the chance of fractures.
Bone marrow is the soft tissue inside bones where blood cells are produced. In multiple myeloma, abnormal plasma cells grow uncontrollably and interfere with normal bone rebuilding.
This often leads to lytic lesions, which are small areas where bone tissue has been destroyed. These weak spots can cause bones to break easily, sometimes without any obvious injury.
Doctors estimate that up to 80 percent of people with multiple myeloma already have fractures or severe bone damage when the disease is first diagnosed.
Apart from the type of cancer, doctors also say the context of a fracture matters. A break after a serious fall is usually straightforward but certain patterns may raise concern.
One major warning sign is a fracture after minimal trauma. This means a bone breaks even though the force involved was very small, such as stepping awkwardly or lifting something light.
Persistent bone pain is another signal. Pain that lasts for weeks, becomes worse at night, or appears before a fracture occurs may suggest that the bone was already weakened.
Swelling around the bone or a lump near the fracture site should also be evaluated carefully. These signs may indicate that the bone had an abnormal growth or tumor before the damage.
Doctors also look for systemic symptoms, which are symptoms affecting the whole body rather than just one area. These may include unexplained weight loss, fatigue, anemia, frequent infections, nausea or constipation.
Experts emphasize that most fractures are still caused by common conditions like osteoporosis or accidental injuries. Cancer is a much rarer explanation.
However, when something about a fracture seems unusual, doctors may recommend additional tests. These can include imaging scans such as X-rays, CT scans, or MRI scans to examine the bone more closely. Blood tests or specialised panels may also be done to look for conditions like multiple myeloma.
Early detection is important because many cancers can be treated more effectively when diagnosed sooner. Doctors advise adults, particularly those in middle age or older, to seek medical advice if a fracture happens with very little force or is accompanied by persistent pain or swelling.
In many cases the explanation will still be something simple like bone thinning. But identifying rare causes early can make a significant difference in treatment and recovery.
As specialists point out, paying attention to unusual symptoms and seeking timely evaluation is often the first step toward protecting long-term health.
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Blood sugar spikes are dangerous as it could trigger inflammation, oxidative stress, and damage blood vessel linings. The most dangerous, risk of type 2 diabetes, cardiovascular diseases and cognitive decline. When people think of blood sugar spikes, they think of food, carbohydrates or sugary food items that should be avoided. However, there are other things too that are not food, but could spike your blood sugar.
NHS doctor, Dr Amir Khan, who is a general physician with NHS England, resident doctor on ITV's Lorraine and Good Morning Britain, and host of the No Appointment Necessary podcast on his Instagram channel highlighted five non-food related reasons that could spike your blood sugar.
"Did you know your blood sugar can spike even if you haven't had a single bite to eat?" He starts his video with this disclaimer and goes on to say, "Let me share five surprising things that can raise your blood sugar and why it might not always be a bad thing."
Dr Khan shares that stress triggers a rise in cortisol levels that activates the body's fight-or-flight response. This signals the liver to release stored glucose into the bloodstream to provide a quick boost of energy. This thus leads to a surge of glucose in blood and leads to the rise of blood sugar levels.
"When you're stressed, your body releases cortisol, the fight or flight hormone that tells your liver to release stored glucose to give you energy. Great if you're running from a tiger, less helpful if you're just stuck in traffic. Remember, chronic stress equals chronic glucose spikes and that is not good for long-term health,” he explains.
He also highlighted that even a single night of poor sleep could increase insulin resistance, which means glucose stays in the bloodstream for longer duration and could lead to elevated blood sugar levels. He said that chronic sleep deprivation could raise the risk of developing type 2 diabetes even in people who try to maintain otherwise a healthy diet.
"One bad night, your body becomes more insulin resistant. That means glucose hangs around in the blood for longer and over time, poor sleep can increase your risk of type 2 diabetes, even if you try your best to eat well," he says.
To many people's shock, he says exercise could temporarily spike blood sugar. "Number three, exercise. Yes, even the good stuff. Certain types of exercises, especially intense or resistance training, can temporarily raise your blood sugars. Why? Well, again, it's your body releasing glucose for fuel, but really importantly, long-term, exercise improves insulin sensitivity, meaning lower blood sugars overall. So, this is not a bad spike,” he explains.
However, he does point out that it is not a bad thing. He notes that certain forms of physical activity, especially intense or resistance training could prompt the body to release more glucose in bloodstream to fuel the muscles. However, he also points out that regular exercise improves insulin sensitivity over time and helps the body regulate sugar more effectively.
“When you're fighting off a bug, your immune system has to ramp up, and that comes with a glucose surge. It's your body's way of fueling the immune response. People living with diabetes often notice higher blood sugar levels when they're unwell. That's totally normal and they may have to adjust their medication accordingly,” explains Dr Khan.
What this means is that when your body is fighting off infection, it releases more glucose in your bloodstream that works as a fuel for your immune system. This is why people with diabetes often notice higher blood sugar when they are unwell. However, he points out that this is body's normal response to combat illness.
"Ladies, this one's for you because it's mainly around your periods or the menopause. In the second half of your menstrual cycle, that's the luteal phase, progesterone levels rise. This can make your cells more insulin resistant, meaning higher blood sugars. And of course, in perimenopause and the menopause, estrogen levels decline, and that comes with insulin sensitivity dropping. So you become more resistant to insulin, leading to more frequent spikes in blood sugar. That's why women in their 40s and 50s may notice weight gain, fatigue, or brain fog which can be linked to blood sugar shifts.”
Dr Khan notes that hormonal fluctuations during different phases of menstrual cycle could also influence blood sugar levels. Higher progesterone during luteal phase could make cells more insulin resistant. When estrogen is declining during perimenopause or menopause, it could further reduce insulin sensitivity.
Dr Khan concludes, “So remember, not all blood sugar spikes are bad. Context matters. But if you're seeing high readings and you're not sure why, it's always worth talking to your doctor and it’s not always about what you're eating.”
Note: This article is based on content available in public knowledge. Health and Me does not promote any user-generated content being as a substitute for medically verified information or prescription.
Credits: Trondheim Sleep Group/St Olav's hospital
Lights will guide you home, but will it treat your mental illness? It could. According to new findings, changing the color of light could help treat mental illness. A psychiatric unit in Trondheim, Norway is testing how light could be used as a potential treatment for mental health conditions like psychosis and depression. The approach is simple, yet innovative that aims on changing the ward's design to help patients in their recovery. As night falls, filters are lowered over windows and lights are changed. This creates a soothing ambiance and eliminates the blue wavelengths that could disrupt body's internal clock.
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The findings have been published in PLOS Medicine, that looked on the patients who were treated in the circadian-adapted ward. The study showed that these patients showed greater clinical improvement and less aggressive behavior. "Just by changing the light spectrum, we can improve the quality of treatment," said Havard Kallestad, a researcher at St Olavs hospital who led the study.
Researchers are now looking at its use for other healthcare areas, which means beyond the psychiatric wards. The UK's National Institute of Health and Care Research (NIHR) has also called for trials to see if this could "reset" the internal clocks of people who are living in care homes to reduce their behavioral disturbances, especially in dementia patients.
Professor Anthony Gordon of the NIHR said that it was about determining if light therapy could be used to reduce anxiety and improve sleep.
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The psychiatric unit was divided in two identical halves with the same layout, staffing, and facilities. The key difference between the two was the evening light environment. One of the wards used blue-depleted lighting from 6pm onwards, where blinds and filters blocked similar light from windows and screens.
Whereas the other ward used standard hospital lighting and the unique design allowed researchers to study the impact of different lighting on patient recovery.
Circadian rhythm is the body's internal 24-hour clock that regulated the sleep-wake cycle, hormones, digestion, and temperature, which aligns them with day and light. It is primarily controlled by light-sensitive brain cells, or what people commonly call the 'body clock'.
Disruption in the cycle could link to various health issues, which includes mental health problems like depression and cardiovascular diseases. This is why the test in Trondheim could prove beneficial in treating patients across the spectrum of illness.
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