Stress is an inevitable part of life, but its consequences are not just mood swings and mental fatigue. Continual stress makes people produce extra cortisol, a hormone that has a critical role in adapting to short-term challenges, but chronically in high quantities it tends to cause harm to the body causing lots of physical and mental disorders.

The adrenal glands produce cortisol, which helps the body control its "fight, flight, or freeze" response. Cortisol temporarily adjusts blood sugar levels, maintains blood pressure, and assists the immune system, among other functions, in short spurts. But when stress persists, cortisol remains high, and necessary functions of the body are interfered with and rendered more susceptible to disease.

According to one survey conducted by the American Psychological Association, stress negatively affects a third of Americans' physical health. Concerns are reinforced by research where studies have shown 80% of primary care visits are stress-related.

But why does stress have such a profound impact? Elevated cortisol limits the immune system's ability to fight infections, disrupts hormonal balance, and triggers inflammation. Over time, these changes can lead to serious health complications.

Signs That High Cortisol Is Stressing Your Body

Persistent Eye Twitches

Do you have involuntary eye spasms? These harmless but annoying twitches often indicate elevated cortisol. The tiny muscles around the eyes are extremely sensitive to stress, contracting or spasming because of cortisol's stimulant-like effects.

Skin Breakouts and Sensitivity

Your skin often reflects what is going on inside your body, and chronic stress can cause inflammatory skin conditions. Elevated cortisol levels stimulate oil production, which exacerbates acne. It also slows down the healing process, worsens conditions like eczema, and contributes to general irritation of the skin.

Frequent Bloating and Digestive Issues

It also interferes with the body's balance of salt and water, which causes fluid retention and bloating. Excess cortisol also slows down blood flow to the digestive system, which further weakens gut bacteria and causes poor digestion, excess gas, and abdominal discomfort.

Weight Fluctuations

High cortisol stimulates the production of insulin, which can cause blood sugar to drop, making people want to eat sugary, high-fat foods. For many, this becomes an excuse to stress-eat and gain weight. For others, the opposite is true: their appetite disappears under stress, causing them to lose weight.

Unexplained Bruising

If you’re noticing random bruises, elevated cortisol could be the culprit. This hormone weakens skin proteins and the walls of small blood vessels, making your skin more fragile and prone to damage.

Cold Symptoms That Won’t Go Away

Do you feel rundown or experience muscle aches, fatigue, or upset stomach regularly? Elevated cortisol mimics cold-like symptoms. Long-term stress also weakens the immune system, making you more susceptible to infections.

Also Read: Stressed At Work? Your Sleep Might Be Paying The Price, New Study Shows

Vision Problems

Chronic stress can damage your eyesight. Elevated cortisol disrupts blood flow to the eyes, increases eye pressure, and raises the risk of glaucoma. Symptoms like dry eyes, blurred vision, and light sensitivity are also common.

Irregular Menstrual Cycles

Irregular Menstrual Cycles that disrupt the menstrual period. In females, this leads to hormonal distress causing irregular or missed periods. Over time, it may also disturb fertility.

Tinnitus or Persistent Ringing in the Ears

If you hear ringing, buzzing, or hissing sounds without an apparent source, stress might be the culprit. Cortisol affects the auditory system by interfering with blood flow and nerve function and could be the trigger for tinnitus.

Increased Inflammation and Chronic Disease

Increased levels of cortisol contribute to inflammation that can exacerbate conditions such as arthritis and promote the development of heart disease. Chronic inflammation is also associated with mental health conditions, including anxiety and depression.

Long-term Consequences of Increased Cortisol

Left unchecked, high cortisol levels can lead to more than just short-term discomfort. Chronic stress has been associated with serious conditions such as heart disease, psychiatric disorders, and metabolic syndromes. A 2013 study published in JAMA Internal Medicine underlined the link between stress and physical health, with recent research in Neurobiology of Stres supporting these findings.

Ways Managing Stress and Cortisol Levels

Managing stress and cortisol levels is essential for maintaining overall health. One effective approach is practicing mindfulness through meditation or yoga, which helps lower cortisol by calming the mind and promoting relaxation. Regular physical exercise, especially aerobic activities, helps reduce stress hormones and boosts endorphins. Prioritizing sleep is crucial, as lack of rest can increase cortisol levels; aim for 7-9 hours per night.

Another remedy is an overall balanced diet full of anti-inflammatory foods like fruits, vegetables, and whole grains that could manage cortisol production. Finally, it would prevent burnout and chronic stress if proper boundaries were set at work and in personal life.

The U-WIN (Universal Immunization Win) platform has been transformative and has helped India tackle the concerning burden of zero-dose children, said Dr NK Arora, an immunization expert and member of the National Technical Advisory Group on Immunisation in India (NTAGI).

In an exclusive conversation with HealthandMe during World Immunization Week 2026, Dr Arora, Executive Director of The INCLEN Trust International, traced the journey of the U-WIN portal and explained how it has strengthened vaccine uptake in the country.

U-WIN is a digital platform and app to help people find vaccination centers near their residences, manage vaccination appointments at health facilities, and maintain vaccination records.

Dr Arora noted that the U-WIN portal created a digital ecosystem that played a critical role in registration, appointment scheduling, vaccine tracking, and real-time monitoring.

The Origin Of U-WIN

U-Win was launched in October 2024 and is available in 12 languages, including English.

Dr Arora, also the chair of the COVID-19 and HPV vaccine working group, shared that during the deadly COVID pandemic in 2020—around July—it became very clear that to vaccinate 140 crore people, some kind of IT platform is needed that will track individuals who had been vaccinated, especially when they needed their second dose, and later, booster doses.

“Everything started somewhere around July 2020, and by January 2021, we had the Co-WIN platform. By mid-April, things were streamlined. The platform gives us a long list of individuals who have been vaccinated. It also helps to know who has been left out of the vaccination.

“It is like a registry of human beings who are getting immunized. And we could send reminders, we could send certificates, and we can also tell the individual when to get their second and third dose,” the expert said.

He noted that as COVID became less intense toward the end of 2021, serious discussions began on using the same platform for routine immunization. This is where the concept of U-WIN came in 2022. It has now been piloted and is gradually being used.

U-WIN: Closing the Gap For Missed and Zero-Dose Children

The UWIN now has the mechanism to ensure that immunization is completed for everyone who registers. One user can register up to 10 people in one mobile number, including citizens/guardians, pregnant women, infants (0-1 years), children (1-7 years), and adolescents (7-19 years).

“The key issue is that tracking provides two or three important inputs. First, it ensures that everyone is getting vaccinated and that it is not dependent on memory. There is a proper record—whether a person or child has received vaccines and what their current status is, including whether the schedule is complete,” Dr Arora said.

“Second, one of the main reasons for missing or delaying the next dose was that mothers often did not remember. Fathers contributed very little to this process, but they also became involved because of the reminder system,” he added.

Another important role of U-WIN is tackling the so-called zero-dose children—those who have never been vaccinated.

“About 4–5 per cent of our eligible population falls into this category, meaning they have not received even the first pentavalent dose. On the face of it, 4–5 per cent may not seem like a huge problem. But when we look at the absolute numbers—out of 26 million—it translates into a very large number, which we cannot afford to miss. So tracking helps identify these children through the micro-plan system”.

U-WIN Enables Life-course Immunization

Also read: World Immunization Week: Vaccines Are Like Insurance, They’re Safe—Take Them, Says Dr NK Arora

“When a child is vaccinated, we know when boosters are due—at one and a half years, then at five years. But none of us remembers this. Even among well-informed parents, this is often forgotten. This system helps address that gap,” Dr. Arora said.

Further, when the same individual becomes eligible for vaccines like HPV—typically between 9 and 14 years—there is again a gap that needs to be addressed.

Certification is another benefit, as it creates a documented process, particularly for programs like oral polio vaccination.

Dr. Arora highlighted that in case of any future pandemic-like situation that requires repeated vaccinations, “we have a mechanism in place”.

“This IT platform has truly transformed the system. There is also a lot of discussion about using similar platforms for TB patients, pregnant women, and other flagship programs like non-communicable diseases. So, for India, digitalisation is at its best when we talk about U-WIN.”

Summer can invite a plethora of health problems in children. Moreover, dehydration is commonly seen when the body loses more fluids than it takes in. It is important to understand that early or subclinical dehydration can present as fatigue, irritability and reduced appetite, often going unnoticed by parents. Hence, parents need to detect the signs and symptoms of dehydration in children and seek timely help. Parents should follow the vital measures suggested by experts and safeguard their well-being.

Are children more prone to dehydration in a heatwave?

Dr Tushar Parikh, Senior Consultant Neonatologist and Head of Department at Motherhood Hospital, Kharadi, Pune, in an interaction with Health and Me, spoke about dehydration in children and how parents can identify it promptly.

“As temperatures rise during the summer months, dehydration becomes a common yet often overlooked problem in children. Dehydration occurs when the body does not have enough fluids to function properly. The causes can include inadequate fluid intake, sweating, prolonged outdoor play, and illnesses such as fever, vomiting and diarrhoea,” Dr Parikh explained.

Children are at a greater risk of dehydration as fluid loss occurs quickly through sweat. Severe dehydration is easier to identify, but early or ‘subclinical’ dehydration often goes unnoticed, silently affecting a child’s health and behaviour. Parents may assume that their child is simply tired or irritable due to the heat, but these could be early warning signs of fluid imbalance. Dehydration is often the last thing that comes to mind. However, it is frequently considered a minor issue in children. Subclinical dehydration refers to mild fluid loss that does not show obvious signs, such as extreme thirst, but still affects the body.

What are the symptoms of dehydration in children?

Dr Parikh stated that many children exhibit symptoms such as tiredness, irritability and poor appetite. They may also complain of headaches, feel dizzy, or show reduced concentration while studying. Another important sign is decreased urination or darker urine, which often goes unnoticed. Over time, if not addressed, this mild dehydration can impact energy levels and mood, and may become severe, requiring hospital admission. Hence, parents must take charge of their child’s health and seek timely attention even for mild dehydration.

How can parents help children when they are dehydrated?

Dr Parikh shared some simple tips that can help beat dehydration in childre. The expert said that dehydration can be prevented in children by encouraging them to drink water regularly. Children should ideally consume at least 2–3 litres of water daily, along with coconut water, buttermilk and fresh fruit juices to stay hydrated. Parents can also include foods such as watermelon, oranges and cucumbers, which help maintain hydration. It is advisable to limit junk, oily, canned and processed foods. Children should avoid playing outdoors during peak heat hours. Parents should dress their children in light, loose cotton clothing, which helps reduce sweating. Monitoring urine colour and frequency can be a simple way to assess a child’s hydration status. Parents should adhere to these tips to prevent dehydration in children.

The liver is one of the body’s most dependable organs, quietly doing its job in the background every single day. It handles over 500 essential functions—from filtering out toxins and producing key proteins to helping with digestion through bile and keeping your metabolism running smoothly. Most of the time, it does all of this without demanding attention.

For years, liver disease has largely been associated with alcohol. But today, a quieter and increasingly common condition is coming into focus: Non-Alcoholic Fatty Liver Disease (NAFLD), or steatosis. Closely linked to the way we live today, it is affecting a growing number of people, often without any clear warning signs. At the heart of this shift are three closely linked factors: ongoing stress, everyday eating habits that have slowly gone off track, and a noticeable drop in physical activity.

Stress, though often brushed aside, has a real and lasting impact on metabolic health. When the body is constantly in a “fight or flight” mode, cortisol levels stay high. Over time, this often shows up as fat, especially around the abdomen, while also affecting how the body handles insulin. As cells become less responsive, insulin levels rise, and the excess glucose is eventually stored as fat. This fat doesn’t just remain visible; it can quietly accumulate in the liver and begin to interfere with how it works. At the same time, persistent low-grade inflammation creates a setting where the condition can slowly worsen over time.

Diet plays an important role as well. Regularly eating processed foods, refined carbs, and added sugars can quietly tip the body into a calorie surplus, slowly straining its metabolic balance. Fructose—commonly found in sweetened drinks and packaged foods—is largely processed by the liver, putting even more pressure on it over time. When consumed in excess, it pushes the body to convert more sugar into fat, which then starts building up within liver cells over time.

A sedentary lifestyle only adds to this, often without us even realizing it. Because there is little mobility, the body becomes inefficient in using fats and carbohydrates. Over time, weight gain occurs, the body develops insulin resistance, and fatty deposits begin to form in the liver.

Sleep, which is usually ignored, is crucial. If there is insufficient or poor-quality sleep, the body’s circadian rhythm will be disrupted, as well as hormones like ghrelin and leptin, which regulate feelings of hunger and fullness. This increases food consumption and reduces energy expenditure, enabling fat deposition.

The hardest thing about NAFLD is that it is a silent disease. In the first stages of NAFLD, there will be no symptoms felt by the patient. This condition is often diagnosed incidentally when patients undergo physical checkups. Thus, untreated steatosis would eventually turn into NASH, wherein inflammation and injury of liver cells occur. The process then proceeds to fibrosis, cirrhosis, and in severe cases, transplantation of the liver.

The reassuring part is that NAFLD can often be reversed when caught early. In many cases, it comes down to simple, steady choices, eating balanced meals with whole grains, fruits, vegetables, and lean proteins, and staying physically active. Small habits like managing stress through mindfulness or yoga, and getting enough sleep, can make a real difference to metabolic health.

For those at higher risk, including people with obesity, diabetes, or high cholesterol, regular health check-ups become especially important. Spotting the condition early gives you a chance to act before it moves into more serious stages.

The liver, after all, keeps working quietly in the background every single day. Looking after it doesn’t require anything extreme, just consistent, everyday choices that add up over time.