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Stress is an inevitable part of life, but its consequences are not just mood swings and mental fatigue. Continual stress makes people produce extra cortisol, a hormone that has a critical role in adapting to short-term challenges, but chronically in high quantities it tends to cause harm to the body causing lots of physical and mental disorders.
The adrenal glands produce cortisol, which helps the body control its "fight, flight, or freeze" response. Cortisol temporarily adjusts blood sugar levels, maintains blood pressure, and assists the immune system, among other functions, in short spurts. But when stress persists, cortisol remains high, and necessary functions of the body are interfered with and rendered more susceptible to disease.
According to one survey conducted by the American Psychological Association, stress negatively affects a third of Americans' physical health. Concerns are reinforced by research where studies have shown 80% of primary care visits are stress-related.
But why does stress have such a profound impact? Elevated cortisol limits the immune system's ability to fight infections, disrupts hormonal balance, and triggers inflammation. Over time, these changes can lead to serious health complications.
Do you have involuntary eye spasms? These harmless but annoying twitches often indicate elevated cortisol. The tiny muscles around the eyes are extremely sensitive to stress, contracting or spasming because of cortisol's stimulant-like effects.
Your skin often reflects what is going on inside your body, and chronic stress can cause inflammatory skin conditions. Elevated cortisol levels stimulate oil production, which exacerbates acne. It also slows down the healing process, worsens conditions like eczema, and contributes to general irritation of the skin.
It also interferes with the body's balance of salt and water, which causes fluid retention and bloating. Excess cortisol also slows down blood flow to the digestive system, which further weakens gut bacteria and causes poor digestion, excess gas, and abdominal discomfort.
High cortisol stimulates the production of insulin, which can cause blood sugar to drop, making people want to eat sugary, high-fat foods. For many, this becomes an excuse to stress-eat and gain weight. For others, the opposite is true: their appetite disappears under stress, causing them to lose weight.
If you’re noticing random bruises, elevated cortisol could be the culprit. This hormone weakens skin proteins and the walls of small blood vessels, making your skin more fragile and prone to damage.
Do you feel rundown or experience muscle aches, fatigue, or upset stomach regularly? Elevated cortisol mimics cold-like symptoms. Long-term stress also weakens the immune system, making you more susceptible to infections.
Also Read: Stressed At Work? Your Sleep Might Be Paying The Price, New Study Shows
Chronic stress can damage your eyesight. Elevated cortisol disrupts blood flow to the eyes, increases eye pressure, and raises the risk of glaucoma. Symptoms like dry eyes, blurred vision, and light sensitivity are also common.
Irregular Menstrual Cycles that disrupt the menstrual period. In females, this leads to hormonal distress causing irregular or missed periods. Over time, it may also disturb fertility.
If you hear ringing, buzzing, or hissing sounds without an apparent source, stress might be the culprit. Cortisol affects the auditory system by interfering with blood flow and nerve function and could be the trigger for tinnitus.
Increased levels of cortisol contribute to inflammation that can exacerbate conditions such as arthritis and promote the development of heart disease. Chronic inflammation is also associated with mental health conditions, including anxiety and depression.
Left unchecked, high cortisol levels can lead to more than just short-term discomfort. Chronic stress has been associated with serious conditions such as heart disease, psychiatric disorders, and metabolic syndromes. A 2013 study published in JAMA Internal Medicine underlined the link between stress and physical health, with recent research in Neurobiology of Stres supporting these findings.
Managing stress and cortisol levels is essential for maintaining overall health. One effective approach is practicing mindfulness through meditation or yoga, which helps lower cortisol by calming the mind and promoting relaxation. Regular physical exercise, especially aerobic activities, helps reduce stress hormones and boosts endorphins. Prioritizing sleep is crucial, as lack of rest can increase cortisol levels; aim for 7-9 hours per night.
Another remedy is an overall balanced diet full of anti-inflammatory foods like fruits, vegetables, and whole grains that could manage cortisol production. Finally, it would prevent burnout and chronic stress if proper boundaries were set at work and in personal life.
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Leptospirosis gained attention after its cases surged in Kerala recently. The infection has also been reported in Maharashtra, Gujarat, Tamil Nadu, and Karnataka. The bacterial infection typically spreads via contact with water or soil that has been contaminated by the urine of animals infected with leptospirosis, especially during floods.
As monsoons are right at our doors, know why it is important to detect and nab dangerous infections like leptospirosis early.
Leptospirosis is a potentially serious bacterial infection sometimes called the "rat fever" because it can cause symptoms similar to the typical symptoms of common viral infections, which may not be noticeable in the early stages. It is caused by the bacteria of the genus Leptospira that are excreted in the urine of infected animals, including rats, cattle, dogs, and pigs.
In the monsoon season, there is a risk of waterlogging and contaminated animal urine mixing with floodwater and soil. Infestation occurs through direct contact with contaminated water or mud on cuts or abrasions or on the mucous membranes of the mouth, nose, and eyes. Those involved in outdoor work, sanitation, farming, construction, or who are walking in flooded streets are especially at risk.
Health and Me spoke to Dr. Sundar Krishnan, Senior Consultant - Internal Medicine, KIMS Hospital, Thane, about how to tackle leptospirosis this monsoon.
Dr. Krishnan says, “In the early stages, it may have flu-like symptoms, and that makes early recognition challenging. Symptoms are sudden onset of high fever, chills, very severe headache, muscle pain especially in the calves and lower back, fatigue, nausea, vomiting, and red eyes.”
The expert also said that occasionally, the patient may also have abdominal pain or diarrhea. He also says it can escalate quickly to jaundice, kidney failure, difficulty breathing, meningitis, internal bleeding, or multi-organ failure and can require immediate medical care.
Dr. Krishnan recommends several prevention tips to tackle leptospirosis in monsoon:
If leptospirosis is diagnosed early and treated with antibiotics, recovery is much quicker, avoiding life-threatening complications. But if detection and treatment are delayed, the kidneys, liver, lungs, and even the brain may be affected.
The expert advises that people who are ill after being exposed to flood water and are facing fever or flu-like symptoms for more than two days should also seek medical help as soon as possible, informing their doctor about their flood water exposure.
Even though the risk of leptospirosis is high during the monsoon, the best way to steer clear of this infection is to educate the masses about its symptoms and prevention. Early clinical intervention can help de-escalate the situation promptly.
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Headaches are one of the most common health complaints and are often caused by stress, lack of sleep, dehydration, excessive screen time, skipped meals, or other lifestyle factors. While most headaches are benign, experts said that frequent or unusual headaches should not be ignored, as they may signal an underlying medical condition that requires evaluation.
The experts told HealthandMe that paying attention to changes in headache frequency, pattern, and associated symptoms can help identify when medical attention is necessary.
According to Dr. Rajneesh Kummar, Vice Chairman & Unit Head, Neurology, Max Super Speciality Hospital, Dwarka, one of the most common concerns is increasing frequency.
“If someone who previously experienced occasional headaches starts getting them several times a week or finds that painkillers are needed more often than before, it is worth getting evaluated,” he told HealthandMe.
“People should seek medical attention if they have headaches more than 10 to 15 days a month, if the headaches are getting worse, or if they are beginning to interfere with work, daily activities, or quality of life,” added Dr. Praveen Gupta, Chairman, MAIINS, Marengo Asia Hospitals, Gurugram. He also noted that medication-overuse headaches can result from taking painkillers regularly, leading to a cycle of recurrent pain.
Also read: Shingles Vaccine May Help Fight Dementia, Suggest Studies
A change in the pattern of headaches should not be ignored. Dr. Kummar said a headache that feels different from what a person has experienced in the past, particularly after the age of 50, deserves medical attention. Headaches that wake a person from sleep, are worse in the early morning, or are associated with vomiting should also be assessed further.
Dr. Gupta advised prompt medical evaluation for people over the age of 50 who develop a new type of headache. He also recommends seeing a doctor if a person has a history of cancer, a weakened immune system, or develops a headache after a head injury.
The neurologists highlight several "red flag" symptoms that require urgent medical assessment. They advised immediate consultation if a headache is accompanied by
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Dr. Kummar stated that many people worry that every headache is related to a brain tumor or another serious brain disorder. Fortunately, this is rarely the case.
However, persistent or unusual headaches should not be self-diagnosed, and timely consultation helps identify the cause and ensures appropriate treatment before the problem begins affecting quality of life, the expert said.
Dr. Gupta told HealthandMe that early diagnosis can help manage common neurological disorders such as migraines, cluster headaches, and chronic tension-type headaches. A thorough history, neurological examination, and imaging studies, when appropriate, can help determine the cause.
The experts emphasize that if headaches are becoming more frequent, changing in patterns, or affecting daily life, it is time to consult a neurologist. Early diagnosis can provide relief, prevent complications, and improve overall quality of life.
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Several recent studies suggest that older adults who receive the shingles vaccine may be less likely to develop dementia, a condition affecting more than 57 million people worldwide.
Shingles is a painful viral infection caused by the reactivation of the varicella-zoster virus (VZV), which can remain dormant after chickenpox and later trigger a blistering rash and severe nerve pain.
A June 2026 study published in the Annals of Internal Medicine suggests that one in 17 dementia cases could potentially be prevented through shingles vaccination.
Researchers at Brown University found that older adults who received the recombinant shingles vaccine (Shingrix) after a stay in a skilled nursing facility had a 24% lower risk of being diagnosed with dementia over four years than those who were not vaccinated.
The study analyzed Medicare and health records from more than 500,000 adults aged 66 and older admitted to skilled nursing facilities. Researchers compared those who received at least one dose of Shingrix with those who remained unvaccinated.
“A lot of previous studies with similar results focused on an older vaccine,” said study author Kaley Hayes, an assistant professor at Brown University’s School of Public Health.
“This study looks at the newest vaccine only in an older, vulnerable adult population who were not up to date with shingles vaccination and are at a very clear clinical point in care: entering a skilled nursing facility.”
The findings add to growing evidence linking shingles vaccination with a lower risk of dementia.
Also read: How To Spot Leptospirosis, Dengue, Malaria During Monsoons? Early Symptoms Not To Neglect
Researchers believe the vaccine may help protect the brain by preventing shingles and the inflammation caused by the virus.
Shingles can cause a “war zone” of inflammation in the brain, said Dr. Jennifer Pauldurai, the medical director of the Inova Brain Health and Memory Disorders Program in Northern Virginia, NBC News reported.
It’s not that the shingles vaccine itself is a “magic pill,” Pauldurai said.
Rather, the vaccine guards against the disease, which is known to disrupt brain health.
The latest findings add to a growing body of international research.
A study involving more than 282,000 older adults in Wales, published in Nature in 2025, found shingles vaccination was associated with a 3.5% lower absolute risk of dementia over seven years.
Another study of more than 101,000 older adults in Australia, published in the Journal of the American Medical Association in 2025, found vaccine eligibility was associated with a 1.8% lower dementia risk over 7.4 years.
Similarly, a study involving more than 232,000 older adults in Canada, published in The Lancet Neurology in 2026, linked shingles vaccine eligibility to a 2% lower dementia risk over 5.5 years.
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After a person recovers from chickenpox, the VZV virus remains dormant in nerve cells and can become active again years or even decades later, particularly when the immune system weakens.
Older adults and people with weakened immune systems are at the highest risk of developing shingles.
According to the NHS, shingles often starts with:
Seek prompt medical attention if:
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