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Stress is an inevitable part of life, but its consequences are not just mood swings and mental fatigue. Continual stress makes people produce extra cortisol, a hormone that has a critical role in adapting to short-term challenges, but chronically in high quantities it tends to cause harm to the body causing lots of physical and mental disorders.
The adrenal glands produce cortisol, which helps the body control its "fight, flight, or freeze" response. Cortisol temporarily adjusts blood sugar levels, maintains blood pressure, and assists the immune system, among other functions, in short spurts. But when stress persists, cortisol remains high, and necessary functions of the body are interfered with and rendered more susceptible to disease.
According to one survey conducted by the American Psychological Association, stress negatively affects a third of Americans' physical health. Concerns are reinforced by research where studies have shown 80% of primary care visits are stress-related.
But why does stress have such a profound impact? Elevated cortisol limits the immune system's ability to fight infections, disrupts hormonal balance, and triggers inflammation. Over time, these changes can lead to serious health complications.
Do you have involuntary eye spasms? These harmless but annoying twitches often indicate elevated cortisol. The tiny muscles around the eyes are extremely sensitive to stress, contracting or spasming because of cortisol's stimulant-like effects.
Your skin often reflects what is going on inside your body, and chronic stress can cause inflammatory skin conditions. Elevated cortisol levels stimulate oil production, which exacerbates acne. It also slows down the healing process, worsens conditions like eczema, and contributes to general irritation of the skin.
It also interferes with the body's balance of salt and water, which causes fluid retention and bloating. Excess cortisol also slows down blood flow to the digestive system, which further weakens gut bacteria and causes poor digestion, excess gas, and abdominal discomfort.
High cortisol stimulates the production of insulin, which can cause blood sugar to drop, making people want to eat sugary, high-fat foods. For many, this becomes an excuse to stress-eat and gain weight. For others, the opposite is true: their appetite disappears under stress, causing them to lose weight.
If you’re noticing random bruises, elevated cortisol could be the culprit. This hormone weakens skin proteins and the walls of small blood vessels, making your skin more fragile and prone to damage.
Do you feel rundown or experience muscle aches, fatigue, or upset stomach regularly? Elevated cortisol mimics cold-like symptoms. Long-term stress also weakens the immune system, making you more susceptible to infections.
Also Read: Stressed At Work? Your Sleep Might Be Paying The Price, New Study Shows
Chronic stress can damage your eyesight. Elevated cortisol disrupts blood flow to the eyes, increases eye pressure, and raises the risk of glaucoma. Symptoms like dry eyes, blurred vision, and light sensitivity are also common.
Irregular Menstrual Cycles that disrupt the menstrual period. In females, this leads to hormonal distress causing irregular or missed periods. Over time, it may also disturb fertility.
If you hear ringing, buzzing, or hissing sounds without an apparent source, stress might be the culprit. Cortisol affects the auditory system by interfering with blood flow and nerve function and could be the trigger for tinnitus.
Increased levels of cortisol contribute to inflammation that can exacerbate conditions such as arthritis and promote the development of heart disease. Chronic inflammation is also associated with mental health conditions, including anxiety and depression.
Left unchecked, high cortisol levels can lead to more than just short-term discomfort. Chronic stress has been associated with serious conditions such as heart disease, psychiatric disorders, and metabolic syndromes. A 2013 study published in JAMA Internal Medicine underlined the link between stress and physical health, with recent research in Neurobiology of Stres supporting these findings.
Managing stress and cortisol levels is essential for maintaining overall health. One effective approach is practicing mindfulness through meditation or yoga, which helps lower cortisol by calming the mind and promoting relaxation. Regular physical exercise, especially aerobic activities, helps reduce stress hormones and boosts endorphins. Prioritizing sleep is crucial, as lack of rest can increase cortisol levels; aim for 7-9 hours per night.
Another remedy is an overall balanced diet full of anti-inflammatory foods like fruits, vegetables, and whole grains that could manage cortisol production. Finally, it would prevent burnout and chronic stress if proper boundaries were set at work and in personal life.
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American actress Olivia Munn has opened up about her journey with deadly breast cancer, which came with no typical symptoms.
In her latest interview on CBS News Sunday Morning, the 45-year-old actress recalled being “faced with the possibility of death” in April 2023, when she was diagnosed with Stage 1 breast cancer.
Importantly, the actress had no symptoms, and even tests like a mammogram and ultrasound gave her a clean chit.
"No symptoms. And I had a clear mammogram and a clear ultrasound," Olivia was quoted as saying.
However, the condition was detected after taking the Lifetime Risk Assessment test -- a free online Q&A that gave her a high score estimating the risk of developing breast cancer in a lifetime. The test marked any score above 20 percent as a high risk. Munn's risk score was 37.3 percent.
The online test — Tyrer-Cuzick Risk Model — is publicly accessible and widely recommended by experts, and it calculates a woman’s five-year and lifetime risk of developing breast cancer using a combination of factors like age, family history, genetics, reproductive history, and more.
Post the assessment, she took "an MRI, which led to an ultrasound, which then led to a biopsy," she explained.
The biopsy showed that she had what she described as "an aggressive, fast-moving cancer" in both of her breasts.
Once she learned the diagnosis, she fought back with everything she had. She got a double mastectomy, an ovariectomy, and a partial hysterectomy. Now her risk score is zero.
Instead of recovering quietly, Olivia made it her mission to raise awareness about the condition — posting about her cancer on social media and telling the world about the risk assessment test.
In the years since Munn started sharing her story, the number of women taking the test has increased by 4,000 percent, the report said.
"Knowing that it's really changed so many people's lives. It's been the most amazing thing. There's no way I could have ever predicted it," she said.
In 2025, Olivia’s mother, Kim, was also diagnosed with breast cancer after taking the same risk assessment test.
In an Instagram post, Munn said her mother was diagnosed with Stage 1 HER2-positive breast cancer, a fast-growing but often treatable type of the disease. Her diagnosis came after Munn encouraged her mom and sister to take a free online breast cancer risk assessment, known as
Also read: Amanda Peet Opens Up About Breast Cancer Battle, Shares Toughest Moment
What Is A Lifetime Risk Assessment Test?
The MagView Tyrer-Cuzick Risk Assessment Calculator is an online tool that helps one calculate their lifetime risk of developing breast cancer.
The tool urges people to reach out to their healthcare professional in case they have any questions about their risk of developing breast cancer and what the best options are for breast cancer screenings or genetic counseling they may have.
Olivia stressed that any woman over 30 should take the test, and if their risk is above 20 percent, they should ask their doctor for a breast MRI.
Also read: Christy Carlson Romano’s Cancer Test Result Shows Why Regular Screening Is Important
Who Should Get Breast Cancer Screening Done?
According to the American Cancer Society, you are considered to be at average risk if you do not have a personal history of breast cancer, a strong family history of it, or a known genetic mutation (like in the BRCA gene) that increases your risk.
This also applies if you have not had chest radiation before the age of 30. These are the breast cancer screening recommendations for women who are at average risk.
Ages 40-44: You have the choice to start getting a mammogram every year.
Ages 45-54: You should get a mammogram every year.
Ages 55 and older: You can switch to getting a mammogram every other year, or you can choose to continue getting one every year.
You should continue to get screened as long as you are in good health and are expected to live at least 10 more years.
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A large new study suggests that about only two to four cups of coffee per day can reduce stress levels as well as lower the risks of developing anxiety and depression.
Researchers from Fudan University in China found that moderate coffee intake is linked to lower stress levels, while both very low and very high consumption don’t offer the same benefit.
Drinking more than four cups may start to increase stress and anxiety, likely because caffeine stimulates the nervous system and raises stress hormones.
Scientists believe this works like a “J-shaped curve”: a little caffeine can improve mood, alertness, and resilience to stress, but too much can overstimulate the body and make stress worse. Supporting research also shows that high caffeine intake is linked to higher perceived stress and anxiety symptoms.
At the top end of the scale, drinking five cups or more each day was associated with a higher risk of mood disorders – so it seems it is possible to overdo the buzz.
"J-shaped associations were identified between coffee consumption and mental disorders, suggesting that a moderate intake of coffee might be beneficial for mental health," write the researchers in their published paper.
In this animal study, scientists at the National University of Singapore have found that sleep-deprived mice struggle to recognize other mice however, mice that were given caffeine for a week before being being sleep-deprived performed much better on tests and did not show the same memory loss.
Additionally, when caffeine was directly applied to brain tissue from sleep-deprived mice, it improved communication between brain cells in this region -- suggesting that caffeine doesn’t just mask tiredness but may also help repair disrupted brain activity.
NUS physiologist Lik-Wei Wong explained: "Sleep deprivation does not just make you tired. It selectively disrupts important memory circuits.
"We found that caffeine can reverse these disruptions at both the molecular and behavioral levels. Its ability to do so suggests that caffeine's benefits may extend beyond simply helping us stay awake."
"Our findings position the CA2 region as a critical hub linking sleep and social memory. This research enhances our understanding towards the biological mechanisms underlying sleep-related cognitive decline. This could inform future approaches to preserving cognitive performance," NSU neuroscientist Sreedharan Sajikumar added.
Based on these results, the study concluded that sleep deprivation increases signaling linked to adenosine, a chemical that promotes sleep but can also weaken memory circuits. But with moderate amounts of intake, caffeine appears to block this effect and help the brain maintain normal function
While the discovery offers a clearer understanding of how sleep, memory and caffeine are connected, the findings are based on mice and more research is needed to confirm if the same benefits apply to humans.
Due to how much caffeine can actually affect one’s body, experts recommend 400 milligrams only per day. That is about four cups, it is also better to consult a doctor about this as caffeine sensitivity is different for people. Some people are more sensitive to caffeine than others.
How you react depends on your health, what medicines you take, and how fast your body processes things. Too much caffeine can cause problems, so it's important to pay attention to how you feel and not go overboard. Here is what happens to your body when you drink too much caffeine daily.
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Atrial fibrillation (AFib) is an irregular and often very rapid heart rhythm, also called an arrhythmia and can create blood clots in the heart, which can increase your risk of having a stroke by five times.
When a person has AFib, the normal beating in the upper chambers of the heart (the two atria) is irregular and blood doesn't flow as well as it should from the atria to the lower chambers of the heart (the two ventricles).
Common symptoms include palpitations (the feeling that your heart is racing, pounding, fluttering or like you have missed heartbeats), chest pain, finding it harder to exercise, tiredness, shortness of breath, dizziness or feeling faint. However, a more severe symptom is a stroke.
Tucked inside the heart is a tiny pouch called the left atrial appendage. When the heart beats erratically, blood can pool and sit still in this pouch instead of flowing normally and still blood tends to clot. If one of those clots breaks free and travels to the brain, it can block blood flow and cause a stroke.
But researchers have now found new technique, in which a magnetically guided liquid is injected into the heart can harden and permanently seal the left atrial appendage from the inside. Early tests in rats and pigs suggest that this method could one day lower the risk of stroke in people with atrial fibrillation.
Based on this technique, researchers inject a magnetically responsive liquid, sometimes called a magnetofluid, directly into the left atrial appendage through a catheter.
Once inside the cavity, an external magnetic field helps guide and hold the fluid in place, so it fills the entire appendage, even against the force of circulating blood.
Within minutes, the liquid reacts with water in the blood and transforms into a soft "magnetogel" that seals off the cavity. Additionally, as the material begins as a liquid, it can adapt precisely to the highly irregular shape of each patient's left atrial appendage.
The death rate from AFib as the primary or a contributing cause of death has been rising for more than two decades.
Over 454,000 people with AFib are hospitalized in the US each year, out of which 158,000 die of the cause. It is estimated that 12.1 million people in the US will have AFib in the US will have AFib by 2050.
Risk factors for AFib include:
Treatment for AFib includes medications to control the heart's rhythm and rate, therapy to shock the heart back to a regular rhythm and procedures to block faulty heart signals.
A person with atrial fibrillation also may have a related heart rhythm disorder called atrial flutter. The treatments for AFib and atrial flutter are similar.
Experts recommend following the below to reduce yor risk of stroke or developing AFib and maintaining heart health:
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