Stress is an inevitable part of life, but its consequences are not just mood swings and mental fatigue. Continual stress makes people produce extra cortisol, a hormone that has a critical role in adapting to short-term challenges, but chronically in high quantities it tends to cause harm to the body causing lots of physical and mental disorders.

The adrenal glands produce cortisol, which helps the body control its "fight, flight, or freeze" response. Cortisol temporarily adjusts blood sugar levels, maintains blood pressure, and assists the immune system, among other functions, in short spurts. But when stress persists, cortisol remains high, and necessary functions of the body are interfered with and rendered more susceptible to disease.

According to one survey conducted by the American Psychological Association, stress negatively affects a third of Americans' physical health. Concerns are reinforced by research where studies have shown 80% of primary care visits are stress-related.

But why does stress have such a profound impact? Elevated cortisol limits the immune system's ability to fight infections, disrupts hormonal balance, and triggers inflammation. Over time, these changes can lead to serious health complications.

Signs That High Cortisol Is Stressing Your Body

Persistent Eye Twitches

Do you have involuntary eye spasms? These harmless but annoying twitches often indicate elevated cortisol. The tiny muscles around the eyes are extremely sensitive to stress, contracting or spasming because of cortisol's stimulant-like effects.

Skin Breakouts and Sensitivity

Your skin often reflects what is going on inside your body, and chronic stress can cause inflammatory skin conditions. Elevated cortisol levels stimulate oil production, which exacerbates acne. It also slows down the healing process, worsens conditions like eczema, and contributes to general irritation of the skin.

Frequent Bloating and Digestive Issues

It also interferes with the body's balance of salt and water, which causes fluid retention and bloating. Excess cortisol also slows down blood flow to the digestive system, which further weakens gut bacteria and causes poor digestion, excess gas, and abdominal discomfort.

Weight Fluctuations

High cortisol stimulates the production of insulin, which can cause blood sugar to drop, making people want to eat sugary, high-fat foods. For many, this becomes an excuse to stress-eat and gain weight. For others, the opposite is true: their appetite disappears under stress, causing them to lose weight.

Unexplained Bruising

If you’re noticing random bruises, elevated cortisol could be the culprit. This hormone weakens skin proteins and the walls of small blood vessels, making your skin more fragile and prone to damage.

Cold Symptoms That Won’t Go Away

Do you feel rundown or experience muscle aches, fatigue, or upset stomach regularly? Elevated cortisol mimics cold-like symptoms. Long-term stress also weakens the immune system, making you more susceptible to infections.

Also Read: Stressed At Work? Your Sleep Might Be Paying The Price, New Study Shows

Vision Problems

Chronic stress can damage your eyesight. Elevated cortisol disrupts blood flow to the eyes, increases eye pressure, and raises the risk of glaucoma. Symptoms like dry eyes, blurred vision, and light sensitivity are also common.

Irregular Menstrual Cycles

Irregular Menstrual Cycles that disrupt the menstrual period. In females, this leads to hormonal distress causing irregular or missed periods. Over time, it may also disturb fertility.

Tinnitus or Persistent Ringing in the Ears

If you hear ringing, buzzing, or hissing sounds without an apparent source, stress might be the culprit. Cortisol affects the auditory system by interfering with blood flow and nerve function and could be the trigger for tinnitus.

Increased Inflammation and Chronic Disease

Increased levels of cortisol contribute to inflammation that can exacerbate conditions such as arthritis and promote the development of heart disease. Chronic inflammation is also associated with mental health conditions, including anxiety and depression.

Long-term Consequences of Increased Cortisol

Left unchecked, high cortisol levels can lead to more than just short-term discomfort. Chronic stress has been associated with serious conditions such as heart disease, psychiatric disorders, and metabolic syndromes. A 2013 study published in JAMA Internal Medicine underlined the link between stress and physical health, with recent research in Neurobiology of Stres supporting these findings.

Ways Managing Stress and Cortisol Levels

Managing stress and cortisol levels is essential for maintaining overall health. One effective approach is practicing mindfulness through meditation or yoga, which helps lower cortisol by calming the mind and promoting relaxation. Regular physical exercise, especially aerobic activities, helps reduce stress hormones and boosts endorphins. Prioritizing sleep is crucial, as lack of rest can increase cortisol levels; aim for 7-9 hours per night.

Another remedy is an overall balanced diet full of anti-inflammatory foods like fruits, vegetables, and whole grains that could manage cortisol production. Finally, it would prevent burnout and chronic stress if proper boundaries were set at work and in personal life.

The World Health Organization (WHO) is urging countries to accelerate efforts to provide proper eye care, as a new Lancet Global Health study shows that nearly half of all people across the world facing cataract‑related blindness still need access to surgery.

As of now, statistical models predict that the global coverage of cataract surgery is set to increase by about 8.4 percent this decade. However, progress needs to accelerate sharply to meet the World Health Assembly target of a 30 percent increase by 2030.

Devora Kestel, Director, WHO Department of Noncommunicable Diseases and Mental Health: "Cataract surgery is one of the most powerful tools we have to restore vision and transform lives. When people regain their sight, they regain independence, dignity, and opportunity."

The literature review, which analyzed reports from 68 country estimates for 2023 and 2024 shows that the African Region faces the greatest gap, with three in four people who need cataract surgery remaining untreated.

Additionally, women are disproportionately affected across all regions, consistently experiencing lower access to care than men.

Researchers noted that the gap in access to surgery was mostly due to long-standing structural barriers, including shortages and unequal distribution of trained eye-care professionals, high out-of-pocket costs, long waiting times and limited awareness or demand for surgery, even where services exist.

In addition, while age is the primary risk factor for cataract, other contributors such as prolonged UV-B exposure, tobacco use, corticosteroid use and diabetes can accelerate its development.

What Is A Cataract?

A cataract is a clouding of the lens of the eye, which is usually clear. For people who develop cataracts, seeing through cloudy lenses is like looking through a frosty or fogged-up window. Clouded vision caused by cataracts can make it more difficult to read, drive a car at night or see afar.

Most cataracts develop slowly and don't disturb eyesight early on. But with time, cataracts will eventually affect vision. Symptoms of cataracts include:

• Clouded, blurred or dim vision.
• Trouble seeing at night.
• Sensitivity to light and glare.
• Need for brighter light for reading and other activities.
• Seeing "halos" around lights.
• Frequent changes in eyeglass or contact lens prescription.
• Fading or yellowing of colors.
• Double vision in one eye.

At first, stronger lighting and eyeglasses can help deal with cataracts. But if impaired vision affects usual activities, cataract surgery might be needed. Surgery is generally a safe, effective procedure.

Can Rising Pollution Levels In India Worsen Eye Health?

As per a Press Trust Of India report, ophthalmologists have said to see a 60% surge in cases of eye problems. They are blaming this to the "toxic cocktail of smoke, particulate matter, and chemical residues from firecracker burning".

The doctors confirmed that most cases now appear with patients who have allergies, dryness, burning sensations and excessive watering in the eyes. The pollution is not only affecting children, but adults are also equally impacted.

Dr Ikeda Lal, Senior Cornea, Cataract and Refractive Surgery Specialist at Delhi Eye Centre and Sir Ganga Ram Hospital told PTI: "Every year after Diwali, we brace for a rise in eye complaints. The number of patients complaining of itching, redness, and irritation has gone up by almost 50-60 per cent."

A study from 2022 published in the International Journal of Environmental Research and Public Health notes the adverse effects of air pollution on the eyes. Air pollution is a mix of complex gas-phase pollutants and particles that are disbursed into the atmosphere and are harmful.

It comprises:

• Sulfur dioxide
• Nitrogen dioxide
• Carbon dioxide
• Nitrogen monoxide
• Carbon monoxide
• Nitrogen oxides
• Particulate matter 2.5 or PM2.5
• Particulate matter 10 or PM10

Air pollution is known to cause cardiovascular disorders, respiratory tract problems, ocular disease, neurologic disease, cancer, and even death, notes the study.

In terms of its impact on the eyes, the pollutants usually work as irritants, which can cause inflammation and irritation in the eyes.

The cornea is the most sensitive structure in the human body due to its innervation in the ocular surface, which makes it extremely sensitive to environmental agents. The pollutants could thus cause conjunctivitis, which could become a frequent problem.

In addition to that, household pollution could also produce volatile organic compounds; for instance, formaldehyde could cause DNA damage in animal cells, and its carcinogenicity has been assessed by many studies too.

People around the world frequently worry about aging, worrying about physical decline, illness, and a loss of independence s they grow older.

However, researchers at the NYU School of Global Public Health have found that women who worry over their declining health may actually speed up the aging process due to the related-psychological stress.

Mariana Rodrigues, a PhD student at NYU School of Global Public Health and the first author of the study, said: "Our research suggests that subjective experiences may be driving objective measures of aging. Aging-related anxiety is not merely a psychological concern, but may leave a mark on the body with real health consequences."

"We know from previous research that anxiety, depression, and mental health in general are associated with a number of physical health outcomes, but until now researchers haven’t focused on whether there is a correlation between worrying about aging and the process of aging itself.

“Women in midlife may also be multiple in roles, including caring for their aging parents. As they see older family members grow older and become sick, they may worry about whether the same thing will happen to them".

After analyzing data from 726 women, the researchers while worrying about declining health, had the strongest associations with biological aging, anxiety about declining attractiveness and fertility were not significantly associated with it.

They theorized that this may be because research shows that health-related concerns are more common and persist over time, while worries about beauty and reproductive health may fade with age.

“Aging is a universal experience,” said Rodrigues. “We need to start a discourse about how we as a society—through our norms, structural factors, and interpersonal relationships—address the challenges of aging.”

Warning Signs You May Be Aging Faster

• Constant fatigue and loss of energy: Everyday tasks feel harder, and the body tires more quickly than before.
• Skin and hair changes: Reduced collagen and keratin production leads to sagging, wrinkles, and thinning or loss of hair.
• Cognitive decline: Memory lapses, difficulty in planning, and problems with calculations may point to aging-related changes in the brain as grey matter begins to shrink.
• Chronic conditions: Lifestyle diseases like diabetes and hypertension are often tied to aging, linked to reduced insulin production and thicker, slower blood flow.

Can Premature Aging Be Prevented?

While no one can stop the clock, adopting healthy habits can slow it down. Regular physical activity, a diet rich in antioxidants from fruits and vegetables, quality sleep, and timely health screenings can all help delay the impact of aging and keep the body functioning better for longer.

Excessive exposure to the sun speeds up skin aging, a process known as photoaging. This alone causes about 90% of the visible changes we see in skin, such as wrinkles, age spots, and rough texture. UV rays also damage cells, which raises the risk of skin cancer.

Blue light and infrared light: The remaining 10% of skin damage comes from high-energy visible (blue) light and infrared light. Blue light comes from the sun and also from screens, while infrared is the heat we feel. These don’t raise cancer risk but they do weaken collagen and elasticity, making skin sag sooner.

Other lifestyle factors that speed up aging include:

• Smoking: Nicotine toxins break down collagen and elastin, causing sagging skin, wrinkles, and a hollow look.
• Poor diet: Diets high in sugar and refined carbs may speed up aging, while diets rich in fruits and vegetables help protect the skin.
• Alcohol: Heavy drinking dehydrates and damages skin over time.
• Lack of sleep: Poor or insufficient sleep has been linked to faster cellular aging.
• Chronic stress: High cortisol levels from stress reduce substances like collagen and hyaluronic acid that keep skin smooth and firm.

In rare cases, certain medical conditions can also cause early aging, such as progeria, Werner syndrome, Cockayne syndrome, Bloom syndrome, and a few other genetic disorders.

Taking semaglutide can lower your risk of heart attacks and other major adverse cardiovascular events, regardless of how much weight you lose or if you have diabetes, according to a study published in The Lancet.

Researchers from University College London (UCL) have found that taking semaglutide drugs such as Ozempic, Wegovy, Rybelsus can reduce the risk of MACE (Major Adverse Cardiovascular Events, defined as cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) by four percent for every 5kg less body weight or 5cm smaller waist.

The Novo Nordisk-funded study analyzed 17,604 people from 41 countries aged 45 years and over, who were overweight and had cardiovascular disease (CVD) but did not have diabetes.

The involved scientists said this finding “suggests there are multiple ways the drug benefits the heart, rather than its protective effect on cardiovascular health being due solely to weight loss”, which may include “supporting the health of the lining of blood vessels, reduced inflammation, improved blood pressure control and lower lipid levels“.

Lead author John Deanfield, professor of cardiology at the UCL Institute of Cardiovascular Science, said: “Abdominal fat is more dangerous for our cardiovascular health than overall weight, and therefore it is not surprising to see a link between reduction in waist size and cardiovascular benefit. However, this still leaves two-thirds of the heart benefits of semaglutide unexplained.

“These findings reframe what we think this medication is doing. It is labelled as a weight-loss jab but its benefits for the heart are not directly related to the amount of weight lost. In fact, it is a drug that directly affects heart disease and other diseases of ageing.”

Can Obesity Raise The Risk Of Death?

People suffering from obesity are 70 percent more likely to be hospitalised or die from an infectious disease, including flu, COVID-19 and pneumonia, according to a Lancet journal study.

Researchers from the UK and Finland, who analyzed over 500,000 people, found that those with a BMI of 30 or higher were at a significantly higher risk compared with people with a healthy BMI between 18.5 and 24.9. The risk escalated as body weight increased.

Dr Solja Nyberg, of the University of Helsinki and the study's first author, noted the problem could worsen and said: “As obesity rates are expected to rise globally, so will the number of deaths and hospitalizations from infectious diseases linked to obesity.

“To reduce the risk of severe infections, as well as other health issues linked with obesity, there is an urgent need for policies that help people stay healthy and support weight-loss, such as access to affordable healthy food and opportunities for physical activity.”

In the meantime, she added, it was “especially important” for those living with obesity to keep up to date with their vaccinations.

According to the World Health Organisation, obesity has been linked to 3.7 million deaths globally in 2024. If strong action is not taken, the number of people living with obesity is expected to double by 2030. Recently, the WHO released its first-ever guideline on the use of Glucagon-Like Peptide-1, or GLP-1, therapies for managing obesity as a chronic and relapsing condition.

“Obesity is a major global health challenge that WHO is committed to addressing by supporting countries and people worldwide to control it effectively and equitably. Our new guidance recognises that obesity is a chronic disease that can be treated with comprehensive and lifelong care,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus.

Childhood Obesity: The Silent Crisis

Childhood obesity is a long-term health condition that develops when a child’s weight is above the healthy range for their age, height, and sex.

According to Mayo Clinic, doctors define it as having a body mass index (BMI) at or above the 95th percentile for children 2 years and older. In recent times, India has begun seeing a worrying rise in childhood obesity cases, especially in cities where lifestyle changes, unhealthy diets, and less physical activity are driving the trend.

In the United States, CDC data from 2017–2020 showed that about 19.7% of children and adolescents between ages 2 and 19 had obesity, roughly 14.7 million young people. Among them, 12.7% were between ages 2–5, 20.7% were 6–11, and 22.2% were 12–19.

Dr Vivek Jain, Senior Director & Unit Head, Paediatrics, Fortis Hospital explains that in recent years, obesity among children has risen sharply due to many factors. Kids are spending more time in front of screens, getting less outdoor play, and attending online classes, all of which cut down their activity levels. At the same time, fast food, sugary drinks, and packaged snacks have become a regular part of diets.

Modern lifestyles also encourage frequent dining out, reliance on processed meals, and irregular eating. Add limited access to safe play areas, heavy academic schedules, and family history of obesity, and the risks become even higher.

Without intervention, obesity in childhood often continues into adulthood, increasing chances of diabetes, high blood pressure, heart problems, and even some cancers.