Every year, World Toilet Day is observed to raise awareness about the global sanitation crisis and encourage action to solve it. The goal set by the United Nation is to achieve safe toilets for all by 2023, as a part of their Sustainable Development Goals.

The UN also states that 3.5 billion people live without proper sanitation and many children also lose their lives due to poor sanitation and unsafe water. This is why World Toilet Day is observed to raise awareness on this issue.

Theme

This year, the theme for World Toilet Day 2024 is "Toilets - A Place for Peace'. This focuses on the growing threat to sanitation that is caused by conflict, climate change, disaster and neglect. When there is a threat to using toilets, it can lead to many health risks.

Not using toilets for too long may lead to Urinary Tract Infection or UTI. For many who do not have access to clean toilets do not drink enough liquid or hold pee for too long. Doctors suggest that holding in pee for too long can cause bacteria to multiply and lead to UTI. By not drinking enough water, your bladder fails to tell the body to pee often, and can cause the bacteria to spread through the urinary tract, which can lead to infection.

Symptoms of UTI:

• Burning or stinging feeling while urinating
• Pain in pelvis or lower abdomen
• Constant urge to empty the bladder
• Strong or foul smelling urine
• Consistently dark urine
• Blood in urine

Holding in pee for too long can also cause your bladder to stretch, making it difficult or even impossible for the bladder to contract and release pee normally. It can also damage your pelvic floor muscles or could lead to kidney stones.

World Toilet Day History And Significance

To prevent such conditions, it is important that everyone has access to clean and safe toilets. In terms of history, the day was established in 2001, by the World Toilet Organization (WTO), which was founded by Jack Sim. However, it was officially recognised by the UN in 2013. The Government of Singapore worked with WTO to create the first UN resolution called Sanitation for All.

India too promotes safe and hygiene toilet through its Swachh Bharat Yojna.

Delhi is witnessing a significant rise in influenza A H1N1 infections, with the cumulative tally reportedly reaching 1,777.

As per National Centre for Disease Control (NCDC) data, Delhi recorded 1,449 H1N1 cases up to August 12, more than six times the 229 cases reported during the same period last year. Mumbai and Bengaluru are also reporting a sharp rise in cases.

Health Ministry Reviews H1N1 Preparedness

Amid the rise, Union Health Minister JP Nadda reviewed preparedness, including:

• Hospital bed availability
• Critical care facilities
• Essential medical supplies
• Influenza surveillance and epidemiological trends
• ILI and SARI trends
• Testing and laboratory surveillance
• Healthcare facilities’ preparedness

The “situation is being closely and continuously monitored”, said Nadda. The Health Minister also emphasized continued vigilance, robust surveillance and proactive preparedness, along with respiratory and hand hygiene.

People with persistent or severe respiratory symptoms, breathing difficulty or other warning signs were advised to seek medical attention promptly.

The Health Ministry is coordinating with States/UTs, hospitals, laboratories and other stakeholders for early detection, timely clinical management and effective surveillance of seasonal influenza, including H1N1.

Doctors Flag Atypical H1N1 Symptoms

Dr. Atul Kakkar, Senior Consultant and Head of Department, Internal Medicine, Sir Gangaram Hospital, told HealthandMe that H1N1 cases are significantly higher than last year, possibly partly due to seasonal changes.

Most patients are presenting with flu-like symptoms, cold, cough, body aches, and upper respiratory tract infections.

However, doctors are also seeing atypical symptoms.

“We are seeing patients having diarrhea also and myalgias, which are getting very, very frequent.”

Patients at extreme ages are more prone to complications and may require oxygen, high-flow oxygen, NIV or BiPAP, he said.

Those at higher risk include people who are unvaccinated against flu, patients undergoing chemotherapy, and those with COPD, bronchial asthma, cancer or on immunosuppressive treatment.

“Evidence shows early antiviral treatment reduces complications and hospital stay, so we must expand rapid diagnostic capacity across primary care centres and ensure affordable antivirals are available at the point of care,” Dr. Sabine Kapasi, Global Health Strategist and UN Advisor, told HealthandMe.

What Is H1N1?

H1N1 is a subtype of influenza A virus. Common symptoms include:

• Fever
• Cough
• Sore throat
• Runny or blocked nose
• Headache
• Fatigue
• Body aches
• Vomiting or diarrhoea, particularly in some children

The virus mainly spreads through respiratory droplets when an infected person coughs, sneezes or talks.

Children can also spread the virus before they realize they are sick.

Red-flag symptoms include:

• Persistent high fever
• Worsening breathlessness
• Chest pain
• Confusion
• Inability to drink

H1N1 Can Affect The Heart

As per experts, H1N1 infection may also be associated with cardiovascular complications, including:

• Heart inflammation
• Abnormal heartbeats
• Worsening heart failure

Dr. Saurabh Gupta, Associate Director, Internal Medicine, Yashoda Medicity, said H1N1 may cause fluctuations in heart rhythm or inflammation involving the heart.

“Those with pre-existing heart conditions should be more vigilant whilst they’re recuperating. As the infection puts more work on the body, you can find that previous heart problems are more noticeable,” he added.

Warning Signs After H1N1

People recovering from H1N1 should seek medical attention if they develop:

• Severe chest pain
• Shortness of breath
• High or fluttering pulse
• Sudden faintness
• Severe weakness.

Research shows that there are an estimated 300 to 450 living supercentenarians—people aged 110 or older—around the world at any given time. Japan is particularly known for healthy ageing, with an average life expectancy of over 84 years and nearly 100,000 centenarians.

While maintaining a healthy and balanced lifestyle may partly explain their longevity, a new study by a A team of Japanese scientists suggests that it may also be linked to an abundance of cancer-fighting immune cells.

The human immune system has specialized cells called CD4 cytotoxic T lymphocytes (CD4 CTLs), which have been shown to kill tumor cells in some cancers.

When a person gets sick, these cells multiply through a process called clonal expansion to help fight infection.

The study, published in the journal Cell Reports, showed that these immune cells may also play a role in healthy ageing among supercentenarians.

“Immune aging is not simply a process of decline,” said first author Kosuke Hashimoto, an associate professor at the University of Osaka in Japan.

“The selective expansion of certain T cells suggests that, even in extreme old age, the immune system may continue to adapt to age-related challenges,” Hashimoto added.

How Do Immune Cells Work In Supercentenarians?

CD4 CTLs are a cellular signature of supercentenarians—people who live to age 110 and beyond. The researchers discovered that these cells expand and adapt within this older population.

“CD4 CTLs are an atypical and relatively rare T cell population,” Hashimoto said. “So, their marked increase in supercentenarians may provide important clues as to how the immune system is maintained in extreme old age.”

What Did the Study Find?

The small study analyzed blood samples from 28 adults divided into three age groups:

• 70–99
• 100–109
• 110 and older

The findings showed that the proportion of CD4 CTLs increased with age, with median percentages of 4%, 9.6% and 17.6%, respectively.

Researchers found that older adults may be responding to persistent immune threats. As a result, CD4 CTLs clone themselves when the immune system is under attack.

The most prominent clone accounted for an average of 33.3% of CD4 CTLs, indicating that older adults may be responding to persistent immune threats. In one centenarian’s blood sample, a single clone accounted for 53.8% of their CD4 CTLs.

Next, researchers matched the receptor sequences of each participant’s top CD4 CTL clone with those in a public database. Nearly three dozen matches belonged to people with cancer, namely lung, breast and liver cancers.

Because none of the centenarians or supercentenarians studied had been diagnosed with these cancers, researchers theorized that their CD4 CTL expansion may reflect early immune responses.

“Some CD4 CTLs may recognize cancer-related targets, although their exact targets remain unknown,” Hashimoto said.

Evidence Remains Preliminary

The study, which focused on T cells circulating in the blood, does not prove that having an abundance of CD4 CTLs prevents cancer or causes a person to live longer.

Hashimoto said the team’s next step is to research how these cells behave in human tissues.

“As we age, abnormal cells, including senescent and cancerous cells, become more common,” Hashimoto said. “Our findings suggest that immune adaptation to these changes may contribute to exceptional longevity.”

Health officials in the US are warning consumers about yet another multistate outbreak of Salmonella and E. coli infections. This time its linked to alfalfa sprouts, which have sickened more than 40 people.

The outbreak comes as the US is also witnessing a major rise in Cyclospora infections, which can cause severe diarrhea. Federal health officials have posted 20 foodborne illness investigations so far this year, with about 10,500 illnesses associated with outbreaks.

Which States Are Reporting Cases?

Minnesota and Wisconsin have reported more than 40 illnesses linked to alfalfa sprouts.

Officials said additional illnesses are being identified in other states, and the number of cases could increase as the investigation continues.

Minnesota

The Minnesota Department of Health and Minnesota Department of Agriculture said 23 Minnesotans became ill between July 8 and August 8 with Salmonella and/or Shiga toxin-producing E. coli (STEC) infections.

Two people have been hospitalized, and no deaths have been reported.

Of the cases, three people had Salmonella, including one who also had STEC O168:H8. Seven people were infected with STEC O103:H25, while 13 had STEC O26:H11.

According to officials, Minnesota reports approximately 1,000 Salmonella infections and 85 STEC infections with the serogroups associated with this outbreak each year.

Wisconsin

Officials in Wisconsin have identified 17 cases, with one person hospitalized.

The Wisconsin cases are connected to a multistate outbreak of STEC and Salmonella infections linked to alfalfa sprouts distributed to restaurants and grocery stores.

Approximately 1,000 Salmonella infections and 500 STEC infections are reported each year in Wisconsin.

Which Alfalfa Sprout Brands Are Linked To The Outbreak?

The illnesses have been linked to alfalfa sprouts produced by Everything Sprouts, a Minnesota grower, and sold under the Calco and Everything Sprouts brands to restaurants and grocery stores.

Health officials recommend checking homes for these products, not eating them and throwing them away.

What Are The Symptoms Of E. Coli Infection?

Shiga toxin-producing Escherichia coli (STEC) is a group of bacteria that make dangerous poisons called Shiga toxins. While most E. coli are harmless, STEC infections can cause:

• Stomach cramps
• Diarrhea, often with bloody stools
• Low-grade or no fever

People usually become sick two to five days after swallowing the bacteria.

Most people recover within five to seven days.

However, STEC infections can also cause hemolytic uremic syndrome (HUS), a severe complication that can lead to acute kidney failure and other serious health problems.

The officials warned that diarrhea caused by STEC infections generally should not be treated with antibiotics, as this can increase the risk of HUS. Anyone who believes they may have an STEC infection should contact a healthcare provider.

What Are The Symptoms Of Salmonella Infection?

Salmonella is a bacterial infection that commonly causes diarrhea and gastrointestinal illness.

Salmonella infection can cause:

• Diarrhea
• Abdominal pain
• Fever

Symptoms usually begin six hours to six days after swallowing the bacteria.

Most people recover from Salmonella infection without medical treatment. However, children, older adults and people with weakened immune systems may develop serious illness requiring medical care.

How To Stay Safe?

Officials advise people to:

• Check their homes for alfalfa sprouts from Everything Sprouts and Calco.
• Do not eat the sprouts.
• Throw them away.
• Anyone who has eaten the sprouts should monitor for symptoms of Salmonella or STEC infection.
• Contact a healthcare provider if symptoms become severe.