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Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.
What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.
Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.
1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.
2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.
3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.
4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.
5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.
ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?
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In a major policy shift, schools and colleges across India are set to introduce comprehensive sex education after the Centre informed the Supreme Court that a nationwide programme on health, safety, relationships and reproductive awareness will soon be rolled out.
The move comes nearly two years after the apex court directed the government to create a structured national framework to improve awareness about sexuality, reproductive health, consent, personal safety and child sexual abuse prevention.
Appearing before a bench of Justices BV Nagarathna and R. Mahadevan, Additional Solicitor General Aishwarya Bhati said the Centre has accepted the recommendations of a 26-member national expert committee. The government plans to implement the curriculum nationwide after the Supreme Court grants its formal approval.
The bench also observed that "sex education is not a Western concept incompatible with Indian societal values," noting that misconceptions have led some states to oppose or ban such programmes despite their public health importance.
The expert panel has recommended making comprehensive sex education a mandatory part of the school curriculum under NEP 2020. Specially trained teachers would conduct brief 15–20 minute sessions twice a week, with lessons tailored to each age group.
Primary school: Personal hygiene, body awareness, and safe and unsafe touch.
Middle and higher classes: Puberty, hormonal changes, consent, personal boundaries, recognising unsafe situations, seeking help, and reproductive and sexual health.
Health experts lauded the move and reiterated that comprehensive sex education is not about encouraging sexual activity. Instead, it equips children with the knowledge and life skills needed to stay safe, make informed decisions and build healthy relationships.
Speaking to HealthandMe, Dr. Ishwar Gilada, the President Emeritus of the AIDS Society of India (ASI) and a Governing Council member of the International AIDS Society (IAS), called the apex Court's directions a landmark moment after decades of advocating for scientific sex education.
He noted that "early sex education can help prevent child sexual abuse among both girls and boys", and also prevent sexually transmitted diseases (STDs) and HIV.
A key myth about sex education is that it will encourage sexual activity. Busting the myth, Dr. Arti Anand, Senior Consultant, Clinical Psychology, Sir Ganga Ram Hospital, said that "comprehensive sex education is about providing children with the right information at the right age, not encouraging sexual activity".
The experts noted that in the absence of accurate information, children often rely on friends or the internet, where myths and misinformation are common.
Instead, Dr Arti said that a good sex education can:
Studies have proven that comprehensive sexuality education can:
Dr. Amit Prakash Singh, Consultant – Internal Medicine, CK Birla Hospital, Delhi, described comprehensive sex education as an essential life-skills programme that goes beyond reproductive health.
Dr. Singh told HealthandMe that the curriculum will help children understand:
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The Trump administration has withdrawn its most far-reaching proposal to restrict gender-affirming care for transgender youth, stepping back from a rule that would have blocked federal Medicaid and Medicare funding for hospitals providing such care.
According to an official document obtained by NPR, the US Department of Health and Human Services (HHS) will not finalize a proposed rule introduced in December 2025 that sought to deny Medicaid and Medicare reimbursements to hospitals offering pediatric gender-affirming care.
The move to drop comes as the HHS received more than 30,000 public comments, including strong opposition from major medical organizations, such as the American Medical Association (AMA) and the Children's Hospital Association. They argued that evidence-based gender-affirming treatments—such as puberty blockers and hormone therapy—are safe and effective for appropriately selected transgender adolescents..
"CMS does not comment on future rulemaking or speculate on potential actions. The Trump Administration rejects ideologically driven surgical interventions on vulnerable children," the Centers for Medicare & Medicaid Services (CMS) told NPR.
In December 2025, Health Secretary Robert F. Kennedy Jr. and Dr. Mehmet Oz, who oversees Medicare and Medicaid, announced plans that would have effectively ended federal funding for hospitals providing gender-affirming care to transgender minors, even in states where such care remains legal.
"So-called gender affirming care has inflicted lasting physical and psychological damage on vulnerable young people. This is not medicine. It is malpractice," Kennedy said at the time.
The administration's move aligns with President Donald Trump's broader policies on transgender healthcare. On his first day back in office, Trump signed an executive order stating that the United States "will not fund, sponsor, promote, assist, or support the so-called 'transition' of a child from one sex to another."
Although the federal funding proposal has been dropped, access to gender-affirming care remains uneven across the United States.
Twenty-seven states have enacted laws banning or restricting gender-affirming care for minors. In several other states, hospitals have reduced or discontinued these services amid ongoing legal and political challenges.
According to a CDC survey, about 3 per cent of US teens aged 13-17—roughly 700,000 adolescents—identify as transgender.
A survey by health policy organization KFF found that fewer than one-third of transgender people reported using medication related to their gender identity, while 16 per cent said they had undergone gender-affirming surgery.
For transgender adolescents, medical treatment most commonly includes puberty blockers and hormone therapy. Gender-affirming surgery for minors remains rare.
Separately, Medicaid is set to undergo major policy changes that could affect millions of Americans, including people living with HIV.
Beginning January 1, 2027, many adult Medicaid beneficiaries will be required to complete at least 80 hours per month of work, volunteering, education, or job training under a new community engagement requirement. Enrollees will also have to verify compliance twice a year to maintain their coverage.
Medicaid is the largest health insurer for people living with HIV in the United States, covering about 46 per cent of this population. Eligibility is primarily based on income, although age and disability status may also qualify individuals.
Health experts have warned that the new reporting requirements could create administrative hurdles, causing some eligible beneficiaries—including people living with HIV—to lose Medicaid coverage and potentially face interruptions in access to essential treatment and care. They added that the loss of Medicaid coverage will not only harm individuals but public health as a whole.
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A new study has challenged long-held beliefs about dementia, suggesting that your location may have a significant impact on whether you may or may not develop neurodegenerative disease.
Researchers from the University of Southern California studied health data from more than 214,000 adults across 21 countries.
They found that while many well-known dementia risk factors are universal, their impact can vary significantly depending on a person's country.
The findings suggest that prevention strategies should be customised to local populations rather than relying on a one-size-fits-all approach.
Also read: Healthy Lifestyle Changes Improve Memory, Thinking In Older Adults At Dementia Risk: The Lancet
The researchers discovered that factors like education, obesity, hearing loss, smoking, hypertension, diabetes, depression, and physical inactivity do not contribute equally to dementia risk across the globe.
In some countries, less education emerged proved to be a strong factor, while in others, cardiovascular health or mental health played a larger role.
"Our findings show that dementia prevention isn't one-size-fits-all," the researchers said, emphasizing that risk profiles differ substantially between countries and should inform future public health policies.
Despite these regional differences, the study also identified encouraging similarities. Several modifiable risk factors consistently influenced dementia risk across multiple countries, reinforcing the importance of maintaining healthy lifestyles while allowing governments to prioritize interventions based on local needs.
"Reducing dementia risk requires not only individual action but also supportive systems and policies that shape people's everyday lives," the WHO says.
Also read: Radio Broadcaster Paul Gambaccini Reveals Alzheimer's Disease Diagnosis
The new research strengthens that message by suggesting that a country's healthcare system, education policies, environmental conditions, and socioeconomic circumstances may all influence how dementia develops within its population.
Experts say that these findings could help in designing effective prevention strategies.
For example, countries where hearing loss has a stronger association with dementia may benefit from expanding hearing screening and access to hearing aids, while others might achieve greater impact by improving cardiovascular care, promoting physical activity, or expanding mental health services.
Previous research has estimated that nearly 45% of dementia cases could potentially be delayed or prevented by addressing modifiable risk factors, including controlling blood pressure, managing diabetes, staying physically active, treating hearing loss, avoiding smoking, and maintaining social life.
Dementia is an umbrella term used to describe a significant decline in mental function that is serious enough to affect everyday life.
It commonly impacts memory, thinking, and reasoning skills. Dementia itself is not a single disease, but a collection of symptoms caused by underlying conditions such as Alzheimer’s disease or vascular dementia.
Common signs include:
The findings come as dementia continues to pose a growing global health challenge. According to the World Health Organization (WHO), dementia affects more than 55 million people worldwide, with nearly 10 million new cases diagnosed each year.
WHO also notes that factors like poverty, limited access to education, healthcare inequality, and employment opportunities can significantly shape an individual's dementia risk.
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