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Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.
What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.
Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.
1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.
2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.
3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.
4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.
5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.
ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?
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Jenny McCarthy, American actress and model in an interview with People revealed her 'horrific' experience of having mouth infections. She is now feeling thankful for being able to eat the Thanksgiving turkey dinner.
She tells People, "I've had nine surgeries this year, on my mouth. I had one infection that turned into another and another, and then I had these growths show up on my eyeballs."
How it started? She said it all started with a failed ceramic dental implant. "My teeth were falling out, implants falling out. They finally had to dig into my jawbone and chipped away, and found I had a deep bone infection. I've been on antibiotics for a year, and have had to eat soft foods only."
While on the November 25 holiday card with she and her husband Donnie Wahlberg, McCarthy looked fit, she revealed that she had "two more mouth surgeries even after that photo was taken". She says that she had been "pretty unlucky".
"As of now, I am able to chew again," she says, "but every time we thought it had cleared up, it came back again. I'd be in massive pain with my jaw swelling up, and at the same time I was getting these growths popping up on my eyeball. People should actually feel a little sorry for me."
Now that she has been well, she is looking forward to celebrating Thanksgiving with her husband. "It's been a little tricky-wicky getting together," she says of balancing their busy schedules.
She revealed that she was shooting The Masked Singer in Los Angeles, and her husband was in Canada with Boston Blue. "So it's been tricky and difficult, which means Thanksgiving and Christmas will mean more to us than ever this year. It's just me and him, at home in Chicago, me cooking a bird, and enjoying each other," she says.
The best part? She says she will be able to enjoy much more than just mashed potatoes now that her mouth infections have cleared up. "I think I'm past the storm. I'm about to chow down," she says.
While McCarthy did not say what she actually had, she did refer that it all started with a "failed ceramic dental implant". Experts point out that due to their anatomical proximity, the eyes and teeth share many nerve and vascular connections. This is why, eye problems could follow a tooth infection.
An infection or a dental abscess of the tooth can easily by continuity spread and be the cause of uveitis, or the infection of uvea. It can also cause other infections in the tear duct, the orbit, lower eyelid, or more.
Studies have also shown that several roots of "spread" due to the infected tooth. For instance, infections in the incisors and canines will spread through the blood or cell. Whereas infections in premolars and molars spread further through the maxillary sinuses. There are 10 to 20% of maxillary sinusitis of dental origin.
Wisdom teeth can reach the lower orbital tissue of the eye, and infections and dental abscesses could spread by the subperiosteum or the set of layers of the periphery of the bones, along with the upper jaw to the tear duct. The infection or abscess can also open a look through the lower edge of the eye socket. This case is quite exceptional except in the case of severe sinusitis.
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Florida aims to become the first US state to strike vaccine mandates from its laws, including long-standing childhood immunisation rules that cover conditions such as polio for entry into public schools.
The proposal drew sharp criticism across the country, prompting the DeSantis administration to slow its plans. After calling for vaccine requirements to be removed from Florida statutes, officials announced that a public meeting will be held in Northwest Florida so residents can respond.
The state’s Department of Health has organised a three-hour session in Panama City Beach on 12 December to review possible changes to the rule governing vaccination requirements for public and private schools. The discussion will cover preschools, grades K-12 and adult education programmes, as per BBC.
Officials have not yet explained what revisions they are considering. In September, Surgeon General Dr Joseph Ladapo said he intended to withdraw the vaccines under his department’s jurisdiction. These include shots for Hepatitis B, varicella, Haemophilus influenzae type b (Hib) and pneumococcal disease. Other vaccines, such as those for polio, diphtheria, rubeola, rubella, pertussis, mumps and tetanus, can only be repealed by the state Legislature. As of 26 November, no bill seeking to overturn vaccination requirements had been introduced.
During a 3 September press event in Valrico, Hillsborough County, Ladapo appeared alongside Governor Ron DeSantis, Lt Governor Jay Collins and other state leaders, including Education Commissioner Anastasios “Stasi” Kamoutsas. They declared their intention to remove all vaccine mandates in Florida, as per BBC.
“Every last one of them is wrong and drips with disdain and slavery,” Ladapo said at the time.
The announcement accompanied the launch of a state version of the “Make America Healthy Again” initiative, which will be led by First Lady Casey DeSantis. At the national level, the MAHA programme is overseen by US Health and Human Services Secretary Robert F Kennedy Jr, who has been assigned to study chronic illness and develop an action plan for reducing childhood diseases, as per Kennedy has previously been linked to vaccine misinformation.
Casey DeSantis expressed her support at the same press conference. “A lot of these drugs, you don’t need them if you live a healthy lifestyle. If you’re eating fruits and vegetables, you can reverse a lot of these chronic conditions,” she said.
The announcement drew immediate criticism from national medical bodies and clinicians throughout the United States.
“We are concerned that today’s announcement by Gov DeSantis will put children in Florida public schools at higher risk for getting sick, and have ripple effects across their community,” said Dr Susan J Kressly, President of the American Academy of Pediatrics.
Sandra Adamson Fryhofer, speaking on behalf of the American Medical Association, urged the state to reconsider. “While there is still time, we urge Florida to reconsider this change to help prevent a rise of infectious disease outbreaks that put health and lives at risk,” she said.
Florida’s kindergarten vaccination rate dropped to 90.6 percent in 2024, the lowest level in more than ten years. Public health experts say that for highly contagious infections such as measles, communities require a rate of at least 95 percent to prevent outbreaks.
Cases of whooping cough have increased sharply. From 1 January to 15 November 2025, the state recorded 1,415 cases, compared with 577 in the same period the previous year, according to the Department of Health’s Reportable Diseases Frequency Report.
Children entering public schools from kindergarten through twelfth grade are currently required to have at least four doses of the TDAP vaccine, which protects against tetanus, diphtheria and pertussis. Religious exemptions are permitted if a family states that immunisation conflicts with their beliefs, as per Herald Tribune.
As of April 2025, the Department of Health estimated that 6.39 percent of children aged five to seventeen held religious exemptions. The true figure may be higher, since parents may withhold data from the Florida SHOTS system, the state’s secure online immunisation database used by healthcare providers.
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Tineke “Tini” Younger shared some devastating news on Wednesday, November 26. The 24-year-old TikTok chef and Next Level Chef alum revealed that one of her twin daughters with husband Antoine Wright Jr. had tragically passed away.
Younger said that their daughter Arya, known as Baby A, died just before reaching 36 weeks of pregnancy. In a heartfelt Instagram post, she wrote, "This isn’t the post I ever imagined I would share once the twins arrived. Unfortunately, earlier this week we lost our sweet girl Arya." She explained that despite being so close to full term, she experienced a placental abruption that caused the loss of her baby.
The surviving twin was born safely and is reportedly breathing independently, according to Younger. She has not shared the name of the second daughter.
Placental abruption, medically referred to as abruptio placentae, is an uncommon yet serious complication during pregnancy. The placenta develops inside the uterus and attaches to its wall, providing essential oxygen and nutrients to the growing baby.
Placental abruption happens when the placenta partially or fully detaches from the uterine wall before delivery. This separation can restrict or completely cut off the baby’s supply of oxygen and nutrients while also causing significant bleeding in the mother. According to the Mayo Clinic, the placenta is an organ that forms in the uterus during pregnancy. When placental abruption occurs, the placenta separates from the inner wall of the uterus before birth, which can deprive the baby of vital oxygen and nutrients and lead to heavy maternal bleeding. In some situations, early delivery may be required to protect both mother and child.
Placental abruption often appears suddenly, and if it is not treated promptly, it can pose serious risks to both the mother and the baby.
Placental abruption is most likely to develop in the last trimester of pregnancy, particularly in the final few weeks before delivery. Signs and symptoms may include:
Abdominal and back pain often start suddenly. The amount of vaginal bleeding can vary widely and does not necessarily reflect how much of the placenta has detached from the uterus. Blood may become trapped inside the uterus, so even in severe cases of placental abruption, there might not be any visible bleeding.
In some instances, placental abruption develops gradually, referred to as chronic abruption. This may cause light, intermittent vaginal bleeding. Babies might grow more slowly than expected, and there could be other complications, such as low amniotic fluid or additional issues affecting fetal development.
The precise cause of placental abruption is often unknown. Healthcare professionals can, however, identify certain factors that increase the risk. For example, abdominal trauma, including falls or accidents, can raise the chances of experiencing a placental abruption.
If you notice any of these symptoms, it is strongly recommended to seek medical care immediately to ensure both your safety and your baby’s.
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