World Cancer Day: The 5 Deadliest Cancers & Key Risk Factors You Should Know

Updated Feb 4, 2025 | 09:48 PM IST

SummaryWhat makes cancer the deadliest depends upon how many people have it and what percentage of those people survive.
5 Deadliest Cancer

Credit: Canva

Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.

What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.

Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.

1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.

2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.

3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.

4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.

5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.

ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?

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Congo Ebola Cases Rise to 676; FIFA World Cup Team Arrives in US After Quarantine

Updated Jun 12, 2026 | 03:58 PM IST

SummaryDemocratic Republic of Congo, battling the 17th outbreak of Ebola virus disease, has now recorded 676 confirmed cases and 136 deaths.
Congo Ebola Cases Rise to 676; FIFA World Cup Team Arrives in US After Quarantine

Credit: Mickyjnrofficial/Instagram

The ongoing Ebola outbreak in the Democratic Republic of Congo (DRC) continues to expand, with the virus spreading to three new health zones in North Kivu and Ituri provinces, according to government officials.

The country, which is battling its 17th Ebola virus disease outbreak, has now recorded 676 confirmed cases and 136 deaths, Health Minister Dr. Samuel-Roger Kamba said in a post on social media platform X.

Ebola Spreads To 3 New Health Zones

Kamba informed that the virus has spread to three new health zones in the country. They are:

Masereka (North Kivu)

Vuhovi (North Kivu)

Kambala (Ituri)

“#EbolaBundibugyo: As of June 10, 676 cumulative confirmed cases — 629 in Ituri, 44 in North Kivu, 3 in South Kivu. Forty-one new cases reported today,” Kamba wrote.

“Three new health zones affected: Masereka and Vuhovi in North Kivu, Kambala in Ituri. Our teams are adapting, surveillance is intensifying. The response follows every signal, in every zone,” he added.

Ebola Recoveries Offer Hope

Also read: Expert Explains Science Behind Patient Recoveries

The outbreak, caused by the rare Bundibugyo strain of the Ebola virus, was officially declared on May 15.

There is currently no approved vaccine or specific treatment for this strain.

The minister also reported total 10 recoveries from the deadly disease.

“#EbolaBundibugyo: Two newly recovered today in the Bunia Health Zone. They are returning home. Every recovery is a victory, a message of hope for our communities. Come get treated quickly — early care saves lives,” Kamba said.

DRC World Cup Team Reaches US

Also read: Ebola Survivors May Face COVID-Like Memory Loss and Brain Issues For Over 7 Years: NIH Study

Meanwhile, the Ebola outbreak has also disrupted the preparations of the Democratic Republic of Congo national football team ahead of the FIFA World Cup.

The squad arrived in the United States after spending three weeks in isolation in Europe due to the outbreak in their home country. US authorities required the team to complete the quarantine period in Belgium before being allowed to enter the country, AFP news agency reported.

DRC cancelled a planned pre-tournament training camp at home and instead based preparations in Belgium.

In addition, a scheduled warm-up match against Chile in Spain was also cancelled over concerns about the spread of the virus.

“We adapted to the situation,” said head coach Sebastien Desabre. “We had to focus, as we have had to adapt often.

“That is what we did. We worked well, we played two tough friendlies, and here we are. Now, it is another step for us.”

The team will be based in Houston during the tournament and is scheduled to play its opening Group K match against Portugal on June 17.

What Is Ebola?

Ebola is a severe and deadly disease caused by a virus mostly found in Africa. The spread of the disease happens through contact with infected body fluids.

Symptoms includes fever, headache, weakness, vomiting, diarrhea, muscle pain, sore throat, and unexplained bleeding. This eventually leads to severe complications like bleeding, organ failure, and death.

Ebola is a highly lethal viral hemorrhagic fever first identified in 1976. Over the past five decades, it has caused over 30 outbreaks, primarily in Central and West Africa. The virus takes its name from the Ebola River in the Democratic Republic of the Congo (DRC).

Three strains of the virus — Ebola virus, Sudan virus, and Bundibugyo virus — have caused the largest outbreaks in Africa. Among them, the Ebola virus is considered the deadliest, with fatality rates reaching up to 90% without treatment.

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Indian Researchers Release World’s Most Detailed 3D Atlas of Human Brainstem

Updated Jun 12, 2026 | 02:00 PM IST

SummaryCalled ANCHOR (Atlas of Neurochemical Characterization of the Human Brainstem with 3D Reconstruction), the atlas provides comprehensive multi-modal 3D maps of the human brainstem across the lifespan, covering the prenatal period, childhood, and adulthood.
Indian Researchers Release World’s Most Detailed 3D Atlas of Human Brainstem

Credit: https://anchor.humanbrain.in/

Researchers at the Indian Institute of Technology Madras (IIT Madras) have released the world’s most detailed 3D atlas of the human brainstem.

Called ANCHOR (Atlas of Neurochemical Characterization of the Human Brainstem with 3D Reconstruction), the atlas was developed using a high-throughput brain imaging and computing platform that transforms whole human brains into 3D cell-resolution atlases.

It provides comprehensive multi-modal 3D maps of the human brainstem across the lifespan, covering the prenatal period, childhood, and adulthood.

The atlas includes more than 200 brainstem nuclei and fiber tracts reconstructed from hundreds of serial sections. To identify distinct neurochemical cell types, researchers overlaid eight complementary immunostains across more than 500 sections, enabling detailed mapping.

Developed by the Sudha Gopalakrishnan Brain Centre (SGBC) at IIT Madras, ANCHOR has been made publicly available to researchers, clinicians, and patients worldwide.

“This is a significant accomplishment in the field of neurobiology. This is a multimodal framework integrating MRI, histology, and detailed chemo-architecture. It will be the most detailed and comprehensive maps of the human brainstem, and made available publicly in digital form. These maps will help in identifying specific cell populations affected in brain stem lesions, which could be critical for clinical applications,” said Prof. Ajay Kumar Sood, Principal Scientific Adviser to the Government of India, during the 3rd BRICS Neuroscience Symposium 2026.

Prof. Mohanasankar Sivaprakasam, Head of SGBC, IIT Madras, said the atlas uses a multimodal image visualization framework that integrates volumetric MRI data with cellular-level images.

“By establishing precise spatial correspondence across these modalities, the atlas enables a seamless transition from gross brain structures in the MRI to cellular-level features. We envision that these maps and atlases will have significant implications for neuroscience and neuromedicine,” he said.

Also read: India AI Summit: Union Health Minister Nadda Launches SAHI And BODH Initiatives To Boost AI In Healthcare

What Is ANCHOR?

The human brainstem contains more than 200 nuclei and fiber tracts and plays a vital role in regulating essential body functions.

ANCHOR is an online platform featuring more than 800 serial histological sections stained for Nissl and seven immunochemical (IHC) markers from three human brainstems representing different stages of life:

  • 25 fetal gestational weeks
  • 9 years old
  • 54 years old
Researchers identified and manually annotated more than 200 structures across these specimens and further characterized them using the seven IHC markers.

The atlas also describes catecholaminergic groups across all three age groups, identifies the protoplasmic commissural dendrites of the hypoglossal nucleus, and describes the pretectal nuclei in the fetal brainstem.

Read More:79th World Health Assembly: India Created Over 880 Million Digital Health IDs, Says J P Nadda

Integrated Online Viewer

ANCHOR includes an online viewer that integrates:

  • Magnetic resonance imaging (MRI)
  • Block-face imaging
  • Nissl-stained serial sections
  • IHC-stained serial sections
  • 3D reconstruction of the entire brainstem.

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Nipah Confirmed In Kerala; Patient Critical, 77 Contacts Under Surveillance

Updated Jun 12, 2026 | 10:15 AM IST

SummaryThe patient's initial symptoms included a high fever about a week ago and was later hospitalized with symptoms suggestive of encephalitis. But as his condition worsened, doctors tested for Nipah infection, which turned positive.
Nipah Confirmed In Kerala; Patient Critical, 77 Contacts Under Surveillance

Credit: iStock

The National Institute of Virology (NIV) in Pune has confirmed Nipah virus infection in a 43-year-old man from Ramanattukara in Kerala's Kozhikode district.

The patient, who was earlier shifted from a private hospital to a dedicated Nipah isolation facility at Kozhikode Government Medical College Hospital, remains in critical condition and is currently on ventilator support under the close supervision of a team of specialists, as per officials.

The patient was initially transferred to the Medical College Hospital after testing positive in a preliminary examination conducted at the Virus Research and Diagnostic Laboratory (VRDL). Following preliminary test results that suggested Nipah infection, the Kerala Health Department swung into action and intensified surveillance and containment measures in Kozhikode district.

77 Contacts Identified Through Tracing Efforts

After confirmation from NIV Pune, health authorities launched extensive contact-tracing efforts. District officials have identified 77 people who may have been exposed to the patient through contact tracing:

  • 15 people have been classified as priority contacts.
  • 2 contacts fall under the highest-risk category.
  • 13 contacts have been categorized as high-risk.
  • The remaining 58 contacts are healthcare workers who may have been exposed to the patient.
  • Notably, the patient's immediate family members—including his wife, two children, father, and mother—have been placed under quarantine.

    In addition, two staff members of a private hospital in Kozhikode who interacted with the patient during earlier treatment have also been advised to remain in quarantine. Samples from five primary contacts have been sent to the VRDL laboratory for testing, as per media reports.

    Also read: Ebola Survivors May Face COVID-Like Memory Loss and Brain Issues For Over 7 Years: NIH Study

    No Need for Containment Zone Yet, Says Minister

    As per District Collector M.S. Madhavikutty, none of the identified contacts are currently showing symptoms and there is no immediate need to declare a containment zone.

    Health Minister K. Muraleedharan also stated that the current situation does not warrant the declaration of a containment zone in Ramanattukara.

    "The 15 priority contacts have been advised to remain in quarantine. A rapid response team meeting was held to ensure the availability of PPE kits and gloves. There is no shortage of medicines, and additional supplies will arrive from Chennai," the minister said.

    Officials Probing Possible Source of Infection

    The patient's initial symptoms included a high fever about a week ago and was later hospitalized with symptoms suggestive of encephalitis. But as his condition worsened, doctors tested for Nipah infection, which turned positive.

    He is likely to have been exposed to the virus while cleaning an old godown in Puthukad, Malappuram district, reportedly connected to his soap manufacturing business.

    Another likely source of infection is a chikoo tree located on the patient's property, where officials have reportedly observed the presence of bats and bird droppings.

    "Anyone developing fever should voluntarily isolate themselves, wear a mask, and avoid close contact with others. However, making masks mandatory for the public is not being considered at present, as the situation does not require such a measure," Madhavikutty told reporters.

    This is the 11th Nipah outbreak reported in Kerala since the virus was first detected in the state in 2018.

    What Is Nipah Virus?

    According to the World Health Organization, Nipah virus is a zoonotic disease, meaning it can spread from animals to humans. It can also be transmitted through contaminated food and, in some cases, directly from person to person.

    In humans, infection can range from asymptomatic illness to severe respiratory disease and fatal encephalitis (brain inflammation). The virus can also infect animals such as pigs, causing significant economic losses for farmers.

    Although outbreaks have been limited mainly to parts of Asia, the virus is known for its high fatality rate and potential to cause severe disease.

    Symptoms of Nipah Virus Infection

    Common symptoms include:

    • Fever
    • Headache
    • Breathing difficulties
    • Cough and sore throat
    • Diarrhea
    • Vomiting
    • Muscle pain
    • Severe weakness
    • Dizziness
    • Altered consciousness in severe cases
    • Encephalitis (brain inflammation)

    Why Is Nipah a Concern?

    Nipah virus is considered a major public health threat because of:

    • Its high mortality rate
    • The ability to spread through close contact
    • The absence of a specific antiviral treatment
    • The lack of an approved vaccine for widespread use

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