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Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.
What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.
Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.
1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.
2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.
3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.
4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.
5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.
ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?
With the patent on semaglutide expiring today in India, NATCO Pharma has become the first drugmaker to launch the generic version of the weight-loss drug in the country.
NATCO Pharma’s generic semaglutide injection prices start at INR 1,290 per month.
“NATCO is the first company to offer generic semaglutide in multi-dose vials with customized syringes… It is the most affordable GLP-1 currently in the Indian market as it is approximately 70 percent cheaper in cost than the pen device and 90 percent cheaper than the price of the innovator’s brand,” the Hyderabad-based company said, in a statement.
The company had received approval from the Central Drugs Standard Control Organization (CDSCO) in February 2026 to manufacture and market the drug, after a clinical comparison study.
Semaglutide works by targeting key areas of the brain involved in appetite regulation and food intake. It reduces hunger, improves satiety, and cuts down food cravings, eventually inducing weight loss.
It also improves insulin resistance and has a beneficial effect on the reduction of cardiometabolic events and risk factors.
NATCO's semaglutide drugs will be sold under brand names SEMANAT and SEMAFULL in multi-dose vial formats. It will be priced:
In comparison, Novo Nordisk's Ozempic and Wegovy in pen devices cost INR 8,800 and INR 10,850, respectively, per month for the starting doses.
NATCO has also signed a distribution partnership with Eris Lifesciences to co-market its therapy in India.
Sun Pharmaceutical Industries, Dr. Reddy’s Laboratories, and Zydus Lifesciences are also expected to introduce their versions of semaglutide on Saturday.
Others in the pipeline include Alkem Laboratories, Torrent Pharmaceuticals, and MSN Laboratories.
With intense competition, analysts believe around 50 branded semaglutide generics will enter the Indian market within months, BBC reported.
Calling it a potential "magic-pill moment" for India, investment bank Jefferies predicted that the semaglutide market in the country could reach $1bn domestically.
Also read: CDSCO threatens action against pharma companies for promoting GLP-1 weight-loss drugs
In January this year, Canada became the first country to lose patent protection for semaglutide. However, the country's health regulator hasn’t approved any generics so far.
Novo Nordisk is expected to lose the patent in 10 more countries, including Brazil, China, South Africa, Turkey, and Canada, by the end of 2026.
In view of losing patent, Novo Nordisk recently cut prices for Wegovy in India. The company also launched its blockbuster brand Ozempic in December.
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Once affecting people who smoked tobacco, lung cancer in India is today more common among people who never smoked. The major reason: exposure to poor air, almost year-round.
Although air pollution has emerged as an important risk for lung cancer, the evidence on this issue from India is limited. To explore more on this, the All India Institute of Medical Sciences, Delhi, today announced undertaking a major study.
The study, dubbed ‘AIRCARE (Air Pollution and Cancer Research Ecosystem): Center for Advanced Research on Environmental Health and Lung Cancer Risk’, will examine the connection between the fine particulate matter 2.5 (PM 2.5) and the risk of lung cancer in the country.
PM2.5 particles, with a diameter of 2.5 micrometers or less, are approximately 30 times smaller than a human hair. It is a significant yet often unseen threat to air quality.
“India is home to some of the most polluted cities in the world, and there is an urgent need to scientifically look at the effects of pollution on people’s health. Lung cancer is one of the most common cancers among males in India, and there is a high number of non-smoking lung cancers among females and young adults,” said Dr. Abhishek Shankar, Assistant Professor, Radiation Oncology at AIIMS, who will lead the study, while addressing the media.
“It is deeply concerning that lung cancer, once assumed to be a disease mostly associated with people who smoke tobacco, is now seeing a rapid increase in incidence amongst people who do not smoke,” he added.
The expert urged the "need to implement policy and management strategies to tackle this disease and mitigate further loss of life”.
It will be the first-of-its-kind scientific study in India to evaluate the effects of exposure to air pollution.
About 1,615 lung cancer cases with 1,615 controls from their family members will be added to the study.
The study will employ both a cohort and case-control design to track the effects of chronic PM 2.5 exposure on lung cancer incidence across various demographics and socio-economic groups.
It will also attempt to isolate an Indian population-specific genetic imprint.
Based on the findings, the researchers aim to develop a risk- based screening model that will include both clinical and molecular components specific to the Indian population and exposure levels.
It will also identify the susceptible population among the cohort who are more at risk of developing lung cancer.
Data from the National Cancer Registry shows that lung cancer affects about 72,000 people and claims 66,000 lives every year in India -- making it one of the leading causes of cancer mortality in the country.
From a smoker’s illness, lung cancer has now emerged as a major concern due to poor air quality. Several doctors across Delhi and Maharashtra have n noted a significant increase in pulmonary cancer due to air pollution.
A 2025 study at a government hospital in North India found that 52 percent of lung cancer cases were among non-smokers.
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The Indian government today constituted the National Dental Commission (NDC), in a major reform to improve the quality of dental education in the country and align it with global standards, said the Ministry of Health and Family Welfare, on the occasion of World Oral Health Day.
The government also announced three autonomous boards under the NDC and repealed the erstwhile Dental Council of India (DCI). The developments were notified on March 19, making the new framework operational from the same date, the Ministry said in a statement.
The NDC aims to introduce essential and long-overdue regulatory reforms in dental education and enhance access to affordable oral healthcare across the country.
The three autonomous bodies aim to support the functioning of the Commission. These are:
The key functions of the National Dental Commission includes:
Every year on March 20, World Oral Health Day is observed to empower people with the knowledge, tools and confidence to secure good oral health.
The 2026 theme is “A Happy Mouth is a Happy Life” raises awareness about the importance of caring for your mouth at every stage of life - from birth through later years.
"Healthy Mouth, Healthy Nation. This World Oral Health Day, let’s raise awareness and take action, practice proper brushing, reduce sugar intake, and prioritize regular dental check-ups. Your smile deserves daily care," the Ministry of Health shared in a post on social media platform X.
Also read: World Oral Health Day: Your Mouth May Signal Disease Before You Even Know, According To Doctor
"A healthy mouth is essential for a healthy body. This World Oral Health Day, let’s focus on building better habits for ourselves and our families," said Union Health Minister JP Nadda.
He called for building up "simple steps like proper brushing, limiting sugary foods, and regular dental check-ups" to maintain good oral health.
"Good oral care not only keeps our smile bright but also supports overall well-being. Let’s use this occasion to raise awareness and commit to maintaining good oral hygiene every day," he added.
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