Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.

What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.

Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.

1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.

2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.

3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.

4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.

5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.

ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?

The cyclospora parasite outbreak in the US is continuing to grow, with cases nearing 900, according to local health officials.

While infections have been reported in about 18 states, Michigan and Ohio continue to see the highest number of cases of the intestinal infection.

As of July 6, 678 cases of cyclosporiasis had been confirmed, an official from the Michigan Department of Health and Human Services (MDHHS) told ABC News. This is an increase from roughly 300 cases reported last week. The state annually records up to 50 cases, but the current outbreak is about 13.5 times higher than average.

According to Dr. Natasha Bagdasarian, an infectious disease physician, epidemiologist, and the chief medical executive for the state of Michigan, the figure is a "moving target," meaning cases are likely to continue rising.

"There is a significant lag time between exposure to contaminated produce or contaminated materials and development of symptoms," she told ABC News. "So it can take a week, sometimes even two weeks between exposure and development of symptoms."

In Ohio, there were 177 cases of cyclosporiasis as of July 2, Ken Gordon, press secretary for the Ohio Department of Health's communications office, was quoted as saying.

Cases have been confirmed across 43 counties in Ohio so far this year, according to Gordon. Nearly 171 cases have been reported since June 20.

Meanwhile, the Centers for Disease Control and Prevention (CDC) reported that 145 cases had been detected in 17 states since May 1, excluding Michigan, as of June 16, with at least 20 people hospitalized. No deaths have been reported.

The CDC said cases ranged in age from 5 to 86 years, with a median age of 42. About 61 per cent of patients were female.

So far, no cases have been linked between states, and health officials are still investigating whether there is a common source of the outbreak in Michigan.

Also read: Cyclospora Parasite Spreads to More US States: Foods to Avoid Right Now

How to Prevent Cyclospora Infection

The CDC recommends following safe food handling practices to reduce the risk of infection:

• Wash your hands with soap and water before and after handling fresh fruits and vegetables.
• Wash all fruits and vegetables thoroughly under running water before eating, cutting, or cooking.
• Produce labeled "prewashed" does not need to be washed again.
• Scrub firm produce, such as melons and cucumbers, with a clean produce brush.
• Cut away any bruised or damaged areas before eating.
• Refrigerate cut, peeled, or cooked fruits and vegetables within two hours.

The parasite spreads through food or water contaminated with human feces and is not spread directly from person to person.

According to Dr. Darien Sutton, an emergency medicine physician, proper handwashing is very important.

"This type of parasite doesn't easily go away with alcohol-based hand sanitizer. So, good old handwashing is really key here," said the ABC News medical correspondent.

What Is Cyclospora cayetanensis?

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Cyclospora cayetanensis is a parasite that causes cyclosporiasis, a form of food poisoning.

People can become infected through contaminated food or water. The infection causes watery diarrhea and other intestinal symptoms.

A Cyclospora infection can be mild or severe and may last for weeks or even months. It is typically treated with antibiotics.

People with weakened immune systems, such as those with HIV/AIDS or cancer, are at greater risk of severe disease.

Symptoms of Cyclospora Infection

Symptoms of cyclosporiasis usually begin within a week of exposure to contaminated food or water and include:

• Watery or explosive diarrhea
• Loss of appetite
• Bloating and gas
• Fatigue (extreme tiredness)
• Low-grade fever
• Nausea
• Stomach cramps
• Vomiting.

The launch of the weight-loss drug Wegovy has sparked fresh concerns among pharmacists in the UK, who warn that the new tablet format could make it easier for manufacturers to produce and sell counterfeit medicines.

Wegovy Demand Sparks Counterfeit Concern

The once-daily semaglutide pill, developed by Novo Nordisk, recently became available through private high street and online pharmacies after receiving approval from the UK's Medicines and Healthcare products Regulatory Agency (MHRA).

While the pill is expected to help patients who are reluctant to use injections, experts fear it may also increase the risk of a growing black market for fake weight-loss drugs.

According to a survey conducted by the National Pharmacy Association (NPA) with 310 pharmacies, 97% believe that the weight loss tablet could lead to an increase in counterfeit products being sold unlawfully.

Olivier Picard, chairman of the National Pharmacy Association said, “As this survey shows, pharmacies are concerned about a dangerous and growing black market for weight loss medicines, with tablet form of medication likely to be easier for criminals to counterfeit.”

He said that all patients must visit an authorised pharmacy for Wegovy pills.

He added: “Patients should only ever obtain weight loss medication from a regulated pharmacy after an appropriate consultation with a healthcare professional. Fake medicines pose a serious risk to health because they may contain harmful ingredients or incorrect doses.”

Also read: Wegovy Weight Loss Pill Available in UK Pharmacies From Today: All You Should Know

Global Concern

Unlike injectable medications of GLP-1, tablets often require less sophisticated manufacturing equipment, which makes it easier to make counterfeits.

As the medicated weight loss market is rising after the popularity of GLP-1 medications increased, criminals can produce fake pills on a large scale, using simple equipment.

Counterfeit GLP-1 medicines have already become a growing global concern. In September 2025, the European Medicines Agency (EMA) said that there had been a sharp rise in illegal forms of semaglutide and other GLP-1 medicines online.

The agency also warned that these fake medicines may contain no active ingredient, improper doses, or harmful substances that can lead to failure of treatment or serious health complications.

Demand for GLP-1 medicines such as Wegovy and Mounjaro has soared worldwide as studies continue to demonstrate significant weight loss benefits.

Also read: Can Ozempic-Like GLP-1 Drugs Slow Aging, Boost Longevity?

Clinical trials of the oral Wegovy tablet have shown participants taking the highest dose lost approximately 14% to 17% of their body weight over 64 weeks when combined with diet and exercise. However, pharmacists say the popularity of these treatments has also created opportunities for fraudsters.

Experts urge consumers to avoid purchasing weight-loss medicines from unofficial online sellers or social media advertisements, regardless of how attractive the prices appear.

Genuine GLP-1 medicines require a medical consultation and prescription, and authorised pharmacies carry out necessary clinical checks before selling them.

About Wegovy

The semaglutide (Wegovy) tablet is the first oral glucagon-like peptide-1 (GLP-1) medicine approved in the UK for weight loss.

It can be prescribed alongside a reduced-calorie diet and increased physical activity for adults who have obesity (BMI of 30 or above), or are overweight (BMI between 27 and 30), and have at least one weight-related comorbidity

The United States Department of Health and Human Services (HHS) has announced more than $281 million in funding opportunities through 15 grant programs aimed at addressing addiction, deaths from overdose, mental illness and strengthening recovery services across the country.

HHS Announces $281 Million To Address Addiction & Recovery

The funding, announced by the Substance Abuse and Mental Health Services Administration (SAMHSA), is supposed to support several health initiatives, including substance use and its treatment, suicide prevention, trauma-informed care, overdose, integrated behavioral healthcare, workforce development, recovery support services, and training for first responders.

Part Of Trump’s Great American Recovery Initiative

The investment forms part of the Trump administration's Great American Recovery Initiative, which seeks to expand healthcare in the midst of the nation's ongoing addiction and mental health crises.

Announcing the initiative, HHS Secretary Robert F. Kennedy Jr. said the funding would help communities get access to treatment, strengthen and improve recovery services, prevent overdoses, and provide frontline workers with the resources needed to save lives.

“We are investing more than $281 million through 15 grant programs to expand treatment, strengthen recovery services, prevent overdose, and equip communities with the tools they need to save lives, restore families, and Make America Healthy Again,” Kennedy said.

SAMHSA Principal Deputy Assistant Secretary Christopher D. Carroll said the grants reflect the agency's commitment to addressing the prevention of addiction and overdose-related deaths and treatment of long-term recovery support. The announcement comes amid continued efforts by the federal government to increase investments in behavioral health.

The grants will support effective treatment, strengthen prevention efforts, expand recovery services, and provide resources for the professionals and organizations working on the front lines of the addiction and mental health crisis,” Carroll said.

Read more: 80 Years Of CDC: How America’s Premiere Health Institution Changed Under Donald Trump’s Administration

Other Behavioural Healthcare Initiatives

Last month, HHS allocated more than $700 million in additional funding opportunities, including support for the 988 Suicide & Crisis Lifeline, Certified Community Behavioral Health Clinics (CCBHCs), homelessness initiatives, and the new STREETS program, which aims to reach enable homeless people get treatment and recovery services.

Earlier this year, SAMHSA also distributed nearly $800 million in block grants to states and territories to strengthen mental health services and substance use prevention, treatment, and recovery programs, highlighting federal efforts to expand behavioral health infrastructure.

Despite these investments, the administration's handling of behavioral health funding has faced scrutiny. In January, the Trump administration briefly canceled nearly $2 billion in addiction and mental health grants before reversing the decision following widespread criticism from lawmakers, public health experts and service providers, who warned that disruptions could jeopardize essential treatment and recovery programs.

The latest funding announcement also comes as the United States continues to grapple with high rates of mental illness and substance use disorders.

SAMHSA says that more than 21 million American adults were grappling with both a mental illness and a substance use disorder in 2024, underscoring the need for integrated treatment and recovery services.