Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.

What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.

Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.

1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.

2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.

3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.

4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.

5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.

ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?

Almost a year after the last Senate-confirmed director of the US Centers for Disease Control and Prevention (CDC), was fired for backing science and vaccines, President Donald Trump has nominated Dr. Erica Schwartz to head the agency, making her his third CDC nominee in less than two years.

Appearing before the Senate Committee on Health, Education, Labor, and Pensions (HELP) for her confirmation hearing on Wednesday, Schwartz pledged to restore public trust in the CDC through transparency and evidence-based decision-making.

However, she also faced pointed questions about vaccine policy, scientific independence, and whether she would resist pressure from Health Secretary Robert F. Kennedy Jr.

Erica Schwartz: 'I Will Never Betray Science'

Schwartz highlighted her military background and said restoring confidence in public health institutions would be her top priority.

"If confirmed, my first priority will be restoring trust in public health institutions through radical transparency and unwavering scientific integrity," she said.

"As CDC director, my sacred responsibility is to provide the American people with public health guidance that is clear, honest, and evidence-based. I will never betray science," she added.

Schwartz previously served as deputy US surgeon general during Trump's first administration and held the rank of rear admiral in the US Coast Guard.

Who Is Dr. Erica Schwartz?

Dr. Erica Schwartz is a physician with an extensive background in medicine, public health, engineering, and law. She holds a medical degree (MD), a Master of Public Health (MPH) in epidemiology, a law degree, and a degree in biomedical engineering.

Before being nominated to lead the CDC, Schwartz held several senior public health and military leadership roles, including:

• Serving as a Navy occupational medicine physician and clinical epidemiologist
• Joining the US Public Health Service, where she was detailed to the US Coast Guard
• Serving as the Chief Medical Officer of the US Coast Guard
• Serving as the Deputy US Surgeon General, where she helped oversee national public health initiatives and emergency preparedness.

Erica Schwartz Backs Vaccines, Calls for Autism Research

Throughout the hearing, Schwartz repeatedly expressed support for vaccines, including mRNA COVID-19 vaccines, and strongly endorsed vitamin K injections for newborns to prevent life-threatening bleeding.

She also acknowledged that scientific evidence does not support a link between vaccines and autism, while arguing that more research is needed to better understand the rising prevalence of autism.

"We owe it to the American people to figure out why one in 30 children now has autism," she said.

Schwartz stated that she did not believe either President Trump or Health Secretary Kennedy would ask her to take actions that would harm public health or violate the law.

She also said she was unaware of Kennedy's decision to cancel nearly $500 million in mRNA vaccine contracts and was unfamiliar with reported cuts to smoking cessation and food safety programmes.

Public Health Experts Express Concern

Although many observers consider Schwartz a qualified nominee with mainstream public health credentials, some experts said her testimony did not provide enough reassurance that she would independently defend scientific evidence if political pressure arose.

Dr. Jeanne Marrazzo, chief executive of the Infectious Diseases Society of America, said she wanted stronger commitments to evidence-based science from leaders overseeing the nation's top public health institutions.

The hearing also renewed criticism of Health Secretary Robert F. Kennedy Jr.'s handling of the CDC.

Several Democratic senators, including Sen. Bernie Sanders, argued that former CDC director Dr. Susan Monarez was removed because she resisted Kennedy's vaccine policies.

"Dr. Monarez, to her credit, stood up for science, public health, and for the scientific method. Frankly, she stood up for protecting the well-being of the American people, and that was the reason that she was fired," Sanders said.

If confirmed by the Senate, Schwartz would replace Dr. Jay Bhattacharya, who’s been serving as acting CDC director since February.

A new Phase II clinical trial has found that a carefully formulated cannabis-based treatment may help alleviate agitation in people with advanced dementia. The findings offer hope for patients and caregivers who face one of the most distressing symptoms of the disease.

The findings are a result of the LiBBY (Life's End Benefits of cannaBidiol and tetrahYdrocannabinol) trial, that was presented at the Alzheimer's Association International Conference (AAIC) 2026 in London.

Researchers say the treatment, which combines purified tetrahydrocannabinol (THC) and cannabidiol (CBD) in an oral formulation, showed significant improvements compared to a placebo.

What Did The Trial Find?

The multicenter, randomized, double-blind, placebo-controlled Phase II study enrolled 120 hospice-eligible adults with Alzheimer's disease or other forms of dementia experiencing significant agitation.

Participants received either the THC/CBD formulation or a placebo for 12 weeks. Researchers assessed agitation using the Cohen-Mansfield Agitation Inventory (CMAI) along with clinician evaluations of behavioral improvement.

According to the trial results, participants in the cannabis treatment group experienced significantly greater reductions in agitation than those given a placebo.

Clinician assessments showed improvement in 83.9% of treated participants after two weeks, compared with 30.5% in the placebo group.

By 12 weeks, improvement was seen in 87.2% of treated participants versus 23.6% receiving placebo. Nearly 90% of treated participants showed overall clinical improvement during the study.

The study's lead investigator, Dr. Jacobo Mintzer of the Medical University of South Carolina, said, "These results were extremely impressive and showed a level of response not seen before in clinical trials related to dementia. Rarely do we see close to 90% of patients in a trial respond positively to a new medication."

He added, "Agitation affects many people with late-stage dementia, causing symptoms such as restlessness, aggression, and emotional distress that can profoundly impact patients and their caregivers. Current treatment options are limited and often carry significant side effects."

Also read: Normal Ageing or Alzheimer's? Doctors Explain Six Key Differences to Watch For

Agitation Is A Major Challenge in Advanced Dementia

Agitation affects the majority of people living with Alzheimer's disease and other dementias, especially in the advanced stages.

Symptoms may include pacing, aggression, yelling, restlessness, irritability, and emotional distress, making day-to-day care increasingly challenging.

It also places a heavy emotional and physical burden on caregivers. Many currently prescribed medications, including antipsychotics and sedatives, may increase the risk of falls, excessive sedation, stroke, or even death in older adults.

A treatment that safely reduces agitation without substantially increasing adverse events could be helpful for the patients as well as caregivers.

Investigators said that the results are the strongest seen so far in clinical trials on agitation in advanced dementia.

Also read: Alzheimer's May Be Detectable Years Before Symptoms, Says Neurology Expert

What Is Dementia?

Dementia is an umbrella term describing a significant decline in mental function that interferes with everyday life. It commonly affects memory, thinking and reasoning abilities and is caused by underlying conditions such as Alzheimer's disease or vascular dementia.

Common Signs of Dementia:

• Memory problems
• Confusion
• Difficulty finding words
• Changes in mood or behavior
• Trouble completing familiar tasks

The Growing Global Burden

Dementia significantly affects an individual's ability to live independently, work and perform daily activities while placing a substantial burden on families and caregivers.

According to the WHO, dementia costs the global economy an estimated US$1.3 trillion every year, with about half of that amount attributed to unpaid care provided by family members and friends.

Lionel Messi is one of the most iconic football players in the world. What many people don't realize is that his athletic career almost ended before it truly began.

As a child, Messi was diagnosed with Growth Hormone Deficiency (GHD), a rare medical condition that affects normal growth and development.

With the ongoing FIFA fever, his story has sparked renewed interest, particularly because Barcelona helped shape football history.

What Is Growth Hormone Deficiency?

Growth Hormone Deficiency is a condition in which the pituitary gland does not produce enough growth hormone, a hormone essential for normal growth in children. Without adequate treatment, children with GHD often experience the following symptoms:

• Slower than normal growth
• Short stature compared to other children of same age
• Delayed physical development
• Reduced muscle mass and bone growth

While growth is the most noticeable concern, modern treatment allows many children to achieve normal or near-normal adult height if diagnosed early.

Also read: American Pro Football Players 4 Times More Likely To Die From Diseases Like ALS, Dementia & Parkinson's: Study

Lionel Messi's Diagnosis

Messi himself has spoken in recent interviews about the financial and emotional challenges his family faced during those years.

Doctors recommended regular treatment with synthetic growth hormone, requiring frequent injections over several years.

At the time, growth hormone therapy reportedly cost around $900 to $1,000 per month, an amount that Messi's family could not afford.

Barcelona Stepped In

Messi's local Argentine club, Newell's Old Boys, initially provided some assistance, but not long-term financial support.

His skills on the field eventually caught the attention of FC Barcelona. The Spanish club agreed to sign the young Argentine and help cover the costs of his medical treatment.

The decision required Messi and his family to relocate from Rosario, Argentina, to Spain, which became one of the most significant turning points in football history.

Also read: Former NFL Star Chris Johnson Reveals ALS Diagnosis; Everything You Need To Know About Lou Gehrig's Disease

Did Growth Hormone Make Messi A Better Footballer?

This remains one of the biggest misconceptions surrounding Messi's football career. Messi received growth hormone therapy as a medically prescribed treatment, not as a performance-enhancing drug.

The treatment was meant to correct a hormone deficiency and allow normal physical development under medical supervision.

Sports medicine experts have long emphasized that therapeutic treatment for Growth Hormone Deficiency is fundamentally different from the illegal misuse of growth hormone for athletic performance.

Can Children With GHD Live Normal Lives?

Today, Growth Hormone Deficiency is a recognized endocrine disorder. When diagnosed early and treated appropriately, many children experience significant improvements in growth and can lead healthy, active lives.

• Treatment typically involves:
• Daily or long-acting growth hormone injections
• Regular monitoring by pediatric endocrinologists
• Periodic assessment of growth and hormone levels

Messi's story is more than a football success story. It underscores the importance of early diagnosis and access to specialized medical care. Pediatricians recommend evaluating children whose height or growth pace consistently falls well below expected levels for their age.