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Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.
What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.
Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.
1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.
2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.
3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.
4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.
5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.
ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?
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One of the country's most popular condiment brands, Everest, is under tight FSSAI scrutiny after the food regulator ordered a temporary ban of sale of its hing (asafoetida) and a few masalas.
The Food Safety and Standards Authority of India (FSSAI) has prohibited the sale of compounded hing manufactured by Everest Food Products and Laljee Godhoo and Company after laboratory testing found samples that did not meet food safety standards.
The regulator has spotted compliance issues in three Everest spice blends. They include egg curry masala, chicken masala, and its widely sold garam masala.
To clarify, the three Everest masalas have not been banned permanently. They have been flagged for non-compliance, and the company has been asked to explain the violations and submit an action plan to resolve the said issues.
The action against hing came after a consumer complaint that prompted FSSAI to begin surveillance of major hing brands.
Samples were collected from Everest's facility in Mumbai and its manufacturing unit in Umbergaon, Gujarat, to be sent for laboratory testing.
According to FSSAI, its compounded hing samples tested contained only 0% to 3% alcohol-soluble extract, despite the prescribed minimum being 5%.
Compounded hing, which is not pure raw asafoetida, is a regulated food product made by blending raw hing with other ingredients like starches, flour, and gum Arabic. The required alcohol-soluble extract helps establish whether sufficient raw asafoetida is present in the final product.
FSSAI said the test results indicated that the products contained 30% to 40% less raw hing than required.
The regulator also found a separate problem in six varieties of raw hing tested at the Laljee Godhoo facility. Their starch content ranged between 15% and 32%, while the permitted maximum is 1%.
The regulator also detected non-compliance in Everest egg curry masala, chicken masala, and garam masala. However, unlike the hing products, these three spice blends have not been prohibited from sale.
The companies have been asked to explain the violations and submit action plans elaborating how they intend to comply with the food safety standards.
FSSAI has also advised the manufacturers to voluntarily recall substandard hing products already in the market.
Also read: US FDA Recalls Injectables Over Fiberglass, Steel Particles: See Affected Drugs
FSSAI's action is a preventive food safety measure. The regulator said the manufacturers must address the violations and ensure their compounded hing meets the prescribed standards. The prohibition on the product will remain in place until compliance requirements are met.
For consumers, the episode also highlights the fact how food adulteration or substandard manufacturing is not always visible to the naked eye. A spice may look, smell and taste perfectly fine while still failing a major food safety standard.
Laboratory testing is therefore crucial for identifying problems like incorrect composition or inadequate levels of the ingredient in a product.
This comes at a time when FSSAI is tightening rules over food standards and labelling. Just days ago, the regulator proposed hexagonal red, front-of-pack warning labels for packaged junk foods that are high in sugar, salt or saturated fats. It told the Supreme Court that the aim is to make such information easier for consumers to understand.
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The Food Safety and Standards Authority of India (FSSAI) has proposed putting prominent red, hexagonal warning labels on the front of packaged junk foods and beverages that are high in saturated fat, sugar or salt.
The proposal was submitted to the Supreme Court on August 28, marking a major update after years of debate over front-of-pack labelling.
The proposed labels would carry warnings like “HIGH FAT”, “HIGH SUGAR”, “HIGH SALT” or “HIGHLY SWEETENED BEVERAGE”, allowing consumers to identify products high in nutrients of concern without having to turn the packet around and decipher the nutrition panel.
At present, packaged foods generally provide nutritional information on the back or side of the package. For many shoppers, comparing the sugar, salt or fat content of several products can require some additional work of flipping and searching.
The proposed design is a red-coloured hexagonal symbol placed prominently on the front of the package. The first phase is expected to apply to products that are high in any two or more of the specified nutrients, according to the proposal reported by Reuters. The proposal also includes exemptions for certain foods that have single ingredients.
Also read: FSSAI Flags Food Firms For Misleading ‘100%’, ‘Energy Drink’, Immunity Claims
A prominent warning on the front of a packet could make it immediately obvious that a product contains high amounts of certain nutrients. This could be particularly useful when consumers are choosing between similar products.
It could also help parents make quicker decisions when buying packaged foods for children, who are increasingly being exposed to processed and ultra-processed foods.
The idea is not necessarily to tell consumers “never eat this”. Instead, the warning provides information before the purchase, allowing people to decide how frequently one should consume a type of packaged food.
A warning label, however, cannot compensate for an overall unhealthy diet, and consumers may still choose products carrying a warning. Its value lies in making important nutritional information harder to overlook.
The proposal comes after growing pressure from health activists and the Supreme Court, which has pushed the government to act on front-of-pack warnings amid concerns over rising obesity and chronic lifestyle diseases in India.
Also read: Centre Bans Cough & Cold Medicines For Children Under 4: What Parents Need To Know
The push for front-of-pack warnings is not coming only from health advocates. A recent LocalCircles survey of more than 83,000 consumers across 314 districts found strong support for prominent warnings on packaged foods and beverages high in sugar, salt or saturated fat.
80% of consumers said FSSAI should mandate such warnings, while another 11% wanted them specifically on ultra-processed foods. That means 91% supported front-of-pack warnings in some form, while only 4% felt existing format of nutrition information was more than enough.
Consumers also appeared to favour a warning that could be understood at a glance. 44% preferred a red warning symbol stating that a product was high in sugar, salt or saturated fat, while 27% chose traffic-light colour coding. Only 2% preferred a conventional black-and-white numerical nutrition panel.
But perhaps the most striking finding was what consumers said they would do with that information. 94% said a prominent warning would influence their buying decision.
Of these, 44% said they would avoid the product altogether, 26% would compare it with healthier alternatives and 24% would buy it less frequently. Only 6% said the warning would not affect their purchase.
The move has faced resistance from parts of the food and beverage industry. Companies and industry groups have argued that warning labels could be confusing or ineffective and that consumers should instead be encouraged to practise portion control.
Reuters reported that Coca-Cola India executive Mili Bhattacharya described it as “very simplistic” to believe that a symbol alone would significantly change people's diets.
Health advocates, however, have argued that consumers deserve clearer information about products that are high in nutrients linked to chronic disease.
Just a day before FSSAI proposed the red warning labels, Nestlé CEO Philipp Navratil said food manufacturers should be consulted as India develops its front-of-pack labelling rules.
According to Reuters, Navratil said the rules should be developed through a scientific approach and with input from food manufacturers.
The industry has previously pushed back against some proposals for warning labels, arguing that nutrition information needs to be presented in a way that gives consumers sufficient context rather than simply flagging individual nutrients.
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The US Food and Drug Administration (FDA) has approved Eli Lilly’s Mounjaro (tirzepatide), typically used to control Type 2 diabetes, to also reduce the risk of heart attack or stroke, the American drug maker said.
Mounjaro is already approved as an adjunct to diet and exercise to improve blood sugar in adults and children aged 10 and older with Type 2 diabetes. It targets the GLP-1 protein and is also used for weight loss. In the US, the obesity version is sold under the brand name Zepbound.
The FDA approved Mounjaro to lower the risk of major adverse cardiovascular events (MACE), including:
Also read: UK Woman Dies After Sudden Abdominal Pain Following Increase In Her Mounjaro Dose
The approval applies to adults with Type 2 diabetes who are at high risk for these events.
“For people with Type 2 diabetes, heart disease is the leading cause of death, and Mounjaro – the number 1 most prescribed branded Type 2 diabetes medicine for adults in the US – now gives them a proven way to lower that risk, adding to the strong foundation it has already built in A1C and weight,” said Kenneth Custer, executive vice president and president, Lilly Cardiometabolic Health.
The FDA approval was based on results from a trial that showed Mounjaro outperformed Trulicity, Lilly’s older diabetes drug, in reducing the risk of heart attack and stroke in a large, head-to-head study.
The trial showed that Mounjaro reduced the risk of major adverse cardiovascular events by 8% more than Trulicity.
It was the largest and longest tirzepatide study to date, enrolling more than 13,000 participants across 30 countries over more than four and a half years.
The most commonly reported adverse events in SURPASS-CVOT for Mounjaro were gastrointestinal-related, generally mild to moderate in severity, and occurred primarily during the dose-escalation period.
Read More: GLP-1 Weight Loss Drugs Ozempic, Wegovy, Mounjaro Tied To Over 60 Reported Deaths In Australia
“Mounjaro is the first and only GIP and GLP-1 receptor agonist proven to lower heart attack, stroke or cardiovascular death risk in adults with Type 2 diabetes at high risk for these events – in addition to its established A1C and weight loss benefits,” according to Lilly.
However, Danish rival Novo Nordisk secured FDA approval for its weight-loss drug Wegovy to lower heart risks in 2024 in overweight or obese adults without diabetes.
In 2025, the FDA also approved its older diabetes drug, Rybelsus, to reduce the risk of major adverse cardiovascular events in diabetic patients.
Mounjaro is a brand name for tirzepatide, an injectable weekly treatment first approved by the US FDA for the control of Type 2 diabetes.
Unlike older weight-loss drugs that act on metabolism or suppress appetite as their primary mechanism, Mounjaro acts on two key hormones: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These control the release of insulin and sensations of fullness.
By mimicking their action, Mounjaro decreases hunger and enhances blood sugar control — two key obstacles in successful weight maintenance.
How Does Mounjaro Work?
The key to Mounjaro’s success is tirzepatide, a dual-acting peptide that acts on receptors in the brain and stomach. When taken, it sets in motion a chain reaction of signals that tell the brain that you are full, helping reduce cravings and overeating.
Mounjaro also makes the body more responsive to insulin. In people with obesity, insulin resistance is frequent and can make weight loss more difficult. By enhancing insulin action, Mounjaro helps the body better control blood sugar and store less fat. In a sense, Mounjaro doesn’t simply allow you to eat less — it allows your body to use what you eat more efficiently.
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