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Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.
What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.
Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.
1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.
2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.
3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.
4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.
5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.
ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?
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The Ebola outbreak in the Democratic Republic of Congo (DRC) is expanding at a rapid pace. According to a senior United Nations humanitarian official, the virus now estimated to be claiming one life every 30 minutes.
Tom Fletcher, UN Under-Secretary-General for Humanitarian Affairs and Emergency Relief Coordinator, issued the warning on August 14, calling for urgent international response as the outbreak continues to overwhelm communities and health systems in the Democratic Republic of Congo.
“The outbreak is the fastest growing on record,” Fletcher said, according to reports, urging the international community to step up support.
The latest warning comes as the outbreak has crossed a grim milestone. According to Reuters, DRC had recorded 4,449 confirmed Ebola cases and 2,061 deaths as of August 11.
The outbreak was officially declared in mid-May, but WHO has since found evidence that transmission may have started months earlier. Early patients were reportedly misdiagnosed with illnesses such as malaria or typhoid, allowing the virus to spread before Ebola was identified.
Currently, the virus has also moved far beyond its epicentre in Ituri province. WHO reported in July that cases had spread across five provinces and 46 health zones, with the outbreak concentrated in Ituri but also affecting North Kivu, South Kivu, Haut-Uele and Tshopo.
More recent reporting indicates that the outbreak has now reached a sixth province, while more than 2,100 deaths have been reported.
Also read: Ebola 2026 Outbreak Spreading Faster Than Any Before, On Track To Become Deadliest: WHO Chief
Apart from an overwhelmed healthcare system, conflict, uncontrolled population displacement, poor infrastructure, lack of protective equipment and mistrust of health authorities are making it harder for health workers to identify contacts and reach patients. Health workers have also gone on strike due to nonpayment of wages, which has further weakened the response.
Reports suggested that 60% to 70% of newly detected infections are occurring outside known contact chains, a crucial sign that indicates contact tracing is struggling to keep up with transmission.
Also read: Ebola Death Toll Tops 2,000 In DRC: New Study Reveals Likely Source Of Bundibugyo Virus Outbreak
The widely used Ervebo vaccine targets the Zaire variant of Ebola, not Bundibugyo virus. WHO says there is currently no licensed vaccine or specific treatment for Bundibugyo virus, although several candidates are now being investigated.
WHO experts have recently recommended a clinical trial to determine whether Ervebo could provide some protection against Bundibugyo, after encouraging results in animal studies.
Meanwhile, clinical trials of potential vaccines and treatments are underway in affected areas.
Despite the challenges, WHO chief Dr Tedros Adhanom Ghebreyesus said significant progress has been made towards containing and eradicating the virus. It includes:
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Kenya recently approved seven semaglutide-based drugs, expanding access to a class of drugs that has rapidly moved from diabetes treatment to one of the most talked-about weight-management therapies.
The Pharmacy and Poisons Board (PPB) said the medicines were assessed by regulatory authorities for quality, safety, and effectiveness. The move adds new options as demand for GLP-1 drugs continues to rise in the country.
Kenya already had Novo Nordisk’s Ozempic and Wegovy in the market. The five newly registered generic semaglutide products have been approved for treating and managing type 2 diabetes. A generic product called Truglyx was also launched in Nairobi in July.
An important thing to remember considering using these drugs is that even though they have the same active ingredient, it does not mean these medicines can be used interchangeably.
“While these products contain the same active ingredient, their approved uses are not necessarily interchangeable and must be understood with reference to the indication approved for each product,” PPB Chief Executive Officer Dr Ahmed Mohamed said.
Also read: GLP-1 Weight Loss Drugs Ozempic, Wegovy, Mounjaro Tied To Over 60 Reported Deaths In Australia
Although Ozempic and Wegovy contain the same active ingredient, they are not simply two names for the same treatment.
Ozempic is approved for adults with type 2 diabetes whose blood sugar is not adequately controlled, alongside diet and physical activity.
Wegovy is intended to be used for weight management in adults with a high BMI, alongside diet and exercise.
That is why the PPB has warned patients against assuming that all semaglutide products can be substituted for one another.
“While these products contain the same active ingredient, their approved uses are not necessarily interchangeable,” PPB Chief Executive Officer Dr Ahmed Mohamed said.
The regulator has also stressed that semaglutide medicines are prescription-only drugs and should be used only after assessment and prescription by a qualified healthcare professional.
Also read: UK Woman Dies After Sudden Abdominal Pain Following Increase In Her Mounjaro Dose
The drugs have become popular for their ability to reduce appetite and help lose weight. But the effects of these drugs extend way beyond the weighing scale.
A 2026 analysis of the SELECT trial found semaglutide was associated with fewer hospital admissions and shorter hospital stays among people with overweight or obesity and cardiovascular disease who did not have diabetes.
At the same time, the rapid expansion of the market means there will be more competition. South Africa’s regulator was reviewing 12 generic semaglutide applications in July after patent expiry opened the door to generic competition.
Brazil also approved five new injectable semaglutide medicines last month, showing that manufacturers are rapidly responding to growing demand of GLP-1 drugs.
Just as GLP-1 medicines are steadily gaining popularity, reports emerged stating that semaglutide had the highest number of reported deaths with suspected associations, followed by Tirzepatide, Liraglutide and Dulaglutide.
62 deaths in Australia have been reported to the medicines regulator, the Therapeutic Goods Administration (TGA), with suspected associations with GLP-1 medicines, including Ozempic, Wegovy and Mounjaro.
The TGA has also received reports of nearly 3,000 serious adverse events involving these medicines, which are used by hundreds of thousands of Australians, The Herald Sun reported.
Reported adverse reactions include nausea, pancreatitis, suicidal thoughts and a rare eye condition that can cause blindness.
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One of the most debated claims that sunscreen may significantly increase the risk of skin cancer is putting an old study back in focus. We took a closer look at the research and it shows a far more complicated picture than social media noise.
The controversy stems from a 2023 study based on data from more than 470,000 UK Biobank participants.
The research studied how genetic and environmental factors interact to impact the risk of skin cancer. It found that people who used sunscreen frequently had higher observed rates of melanoma, basal cell carcinoma, and cutaneous squamous cell carcinoma.
Compared to people who rarely or never reported using sunscreen, those who always used it had an observed relative risk of about 3.92 for invasive melanoma, 2.40 for basal cell carcinoma, and 2.26 for squamous cell carcinoma.
The the crucial part of the study is that it did not establish that sunscreen directly causes skin cancer.
The observational research was primarily designed to investigate gene-environment interactions, not to test whether sunscreen causes skin cancer.
The authors themselves described the sunscreen association as surprising and discussed several possible explanations. One of them is “sunscreen paradox.”
Also read: Scientists Find Rare Contagious Skin Cancer In Fish From US, Canada: Should Humans Worry?
People who spend more time outdoors, have accumulated more UV exposure, or already have a higher risk of skin cancer may be more likely to use sunscreen in the first place. Sunscreen use can therefore become a marker of higher sun exposure rather than the cause of the cancer.
Lead author Ivan Litvinov told AAP FactCheck that the viral interpretation had misrepresented the findings. “The post misinterpreted the results of our study,” he said.
Litvinov also explained that sunscreen can create a false sense of security when people use too little, fail to reapply it or treat it as permission to stay in the sun longer. This indirectly contributes to the risk of skin cancer. “When sunscreen is used as a ‘permission to tan’, problems arise,” he said.
Current evidence does not support the conclusion that one must stop using sunscreen to avoid skin cancer.
A randomized trial based on 1,621 adults in Australia found that regular sunscreen use was linked with fewer melanomas over long-term follow-up. Invasive melanoma was substantially lower among those assigned to daily sunscreen use.
More recently, a 2026 review of photoprotection concluded that daily sunscreen use reduces actinic keratoses and cutaneous squamous cell carcinoma in high-risk people, although evidence for basal cell carcinoma and melanoma prevention is more heterogeneous.
Also read: How Vitamin D Helps Protect Your Skin And Lower Cancer Risks Naturally
While sunscreen is important, one must follow some other steps to ensure complete protection. Here are some tips you should remember according to American Academy of Dermatology Association.
The sun's rays are most powerful between 10 a.m. and 2 p.m. During these hours, it's best to seek shade. A good rule of thumb: if your shadow is shorter than you are, the sun is very strong, and you should definitely look for some cover.
Whenever you can, wear sun-protective clothing. This means choosing things like a lightweight, long-sleeved shirt, long pants, a wide-brimmed hat, and sunglasses with UV protection.
For even better defense, look for clothing labels that have an Ultraviolet Protection Factor (UPF) number, which tells you how much UV radiation the fabric blocks.
Both the sun and tanning beds give off harmful ultraviolet (UV) light, which can cause skin cancer and wrinkles. It's best to avoid tanning beds completely.
If you want to have a tanned look, consider using a self-tanning product instead, but remember to still use sunscreen along with it for actual sun protection.
You need to be especially cautious when you're near water, snow, or sand. These surfaces are highly reflective, meaning they bounce back the sun's damaging rays, which can significantly increase your chance of getting a sunburn.
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