World Cancer Day: The 5 Deadliest Cancers & Key Risk Factors You Should Know

Updated Feb 4, 2025 | 09:48 PM IST

SummaryWhat makes cancer the deadliest depends upon how many people have it and what percentage of those people survive.
5 Deadliest Cancer

Credit: Canva

Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.

What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.

Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.

1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.

2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.

3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.

4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.

5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.

ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?

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India Suffers Second-Highest Economic Burden Globally Due to Diabetes, Study Finds

Updated Jan 13, 2026 | 06:51 PM IST

SummaryAccording to a Nature Medicine study, India faces the second highest economic burden of INT11.4 trillion due to this chronic condition. Only the United States ranks higher, while China comes in third. Over 100 million people across India suffer from the chronic condition while another 136 million are living with prediabetes.
India Suffers Second-Highest Economic Burden Globally Due to Diabetes, Study Finds

Credit: Canva

Diabetes isn't just costing Indians their lifelong savings, it's also costing the country INT11.4 trillion.

According to a Nature Medicine study, India faces the second highest economic burden due to this chronic condition. Only the United States ranks higher, with costs touching INT 16.5 trillion, while China comes in third at INT 11 trillion.

While excluding informal care provided by family members, the global costs comes around INT 10 trillion which is about 0.2 per cent of the world’s annual gross domestic product (GDP).

However, if informal care is factored in, costs goes up to INT152 trillion or 1.7 per cent of the world’s yearly GDP, as per the study. (An international dollar, or INT$, is a statistical unit that has the same purchasing power as a US dollar).

The scientists estimated that the economic impact of diabetes was much more than Alzheimer’s disease or cancer in the top three countries.

The Diabetes Crisis In India

Diabetes is a chronic condition affecting several aspects of physical and mental health. It occurs when either the body can’t make enough insulin or can’t use it effectively, which impairs several functions.

Often referred to as the 'Diabetes capital of the world', over 100 million people across India suffer from the chronic condition while another 136 million are living with prediabetes.

According to Pharmeasy 2025 Diabetes Report, one in two people show high blood sugar levels when tested and over 90 percent of reports with high blood sugar also showed abnormality in one or the other parameters for liver, lipid, heart or thyroid issues.

Also known as a 'Silent Killer', diabetes can develop and progress quietly in the body, often without clear or early symptoms. Multiple studies show that over 50 percent of people with diabetes in India are undiagnosed or unaware of their condition.

When left undiagnosed and untreated, diabetes can cause severe complications across the body including heart disease, kidney damage or vision loss. These complications disproportionately affect vulnerable parts of the population, especially those in rural areas without access to proper testing and treatment.

Despite the growing economic burden, India faces systemic challenges in addressing diabetes, including inadequate healthcare infrastructure, low public awareness and fragmented policy responses.

What Did The Study Find?

Researchers, including those from the International Institute for Applied Systems Analysis and the Vienna University of Economics and Business in Austria, calculated the economic impact of diabetes across 204 countries from 2020 to 2050.

They evaluated costs based on medical expenses, productivity losses and caregiving.

While the burden in the US is largely due to high treatment costs and loss of physical capital, the high costs are mainly driven by the sheer number of people affected in India and China, the researchers said.

Author Klaus Prettner, professor of macroeconomics and digitalization at the Vienna University of Economics and Business noted of the results: "Caregivers often drop out of the labor market, at least partially, which creates additional economic costs."

"This is a stark illustration of how medical treatment regimes for chronic diseases such as diabetes are accessible to high income countries only," co-author Michael Kuhn, acting economic frontiers research group leader at the International Institute for Applied Systems Analysis, added.

Based on the results, the scientists said promoting healthier lifestyle, regular physical activity and a balanced diet is the most effective way to prevent diabetes and reduce its economic impact in each country in the long run.

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‘It Ends With Us’ Author Colleen Hoover Reveals Cancer Diagnosis As She Undergoes Radiation

Updated Jan 13, 2026 | 11:12 AM IST

SummaryColleen Hoover, the producer of Blake Lively's It Ends With US, took to social media to reveal that she is left with one more round of radiation, a month after she said that she had been diagnosed with cancer and had undergone surgery. It remains unclear which kind of cancer she has been suffering from
‘It Ends With Us’ Author Colleen Hoover Reveals Cancer Diagnosis As She Undergoes Radiation

Credit: Instagram/ColleenHoover

Colleen Hoover, the best-selling author of 'Regretting You' and 'Verity', has revealed that she has undergone treatment for cancer.

On January 12, Hoover announced via her Instagram Stories that she has one more day of radiation left at Texas Oncology.

"Second to last day of radiation," she captioned the post on her Instagram Stories. "I wish I could blame my hair and facial expressions on @Texas.Oncology, but they've been great. Hope you never need them, but highly recommend them."

In December 2025, the 46-year-old writer wrote on her Facebook page that she had been diagnosed with cancer and had undergone surgery. The film producer also noted that she would only need radiation, but not chemotherapy as a treatment plan.

Hoover said she had been in Canada filming Reminds of Him when she noticed she “had recurring health issues that I continued to put off until the movie was finished" and a check-up revealed that she had developed cancer.

What Kind Of Cancer Does She Have?

While she is yet to reveal which kind of cancer she is receiving treatment for, Hoover has confirmed it was not caused by family genes, HPV or excessive hormones.

In a Facebook post from January 9, she noted that the reason for her illness is 'more than likely' to be environmental/lifestyle, which can be credited to a lack of exercise, poor diet and stress.

"I’m happy and grateful to be alive but I hate vegetables. I hate when I have to get off the couch. I hate sweating. I hate when science is right. If you see me at the gym, don’t even tell me good job. If you see me at a restaurant eating grilled chicken and drinking water, I’m probably real mad about it," she wrote in a heartfelt moment.

Credit: Instagram/Colleen Hoover

Why Has Hoover Been Missing From Public Eye?

Hoover's health updates and cancer treatment come amid a series of cancelled public events. In October 2025, she announced she would not attend the premiere of Regretting You, her latest movie adaptation.

In a sentimental Instagram post, she told her fans: "I’m super bummed, but am having an unavoidable surgery and can’t travel for a while,” Hoover wrote in her Instagram post at the time. I’ll live vicariously through you guys. So sad to miss this movie release and premiere, but so grateful to all the actors and the team who put this together.”

Woman Down is Hoover’s next book release set for January 13. However, the author has had to tell fans that a book-signing tour has not been set up yet and she will not be meeting with the public for now.

“I wanted to make this post and be transparent about why that is. I’m not saying I won’t be up to doing at least one signing, but I just won’t know until I know," she said.

Meanwhile, throughout 2025, production on her hit novel, Verity, has begun in 2025, with Anne Hathaway and Josh Hartnett, being photographed during scenes last February. Additionally, her third movie adaptation, Reminders of Him, is also set to hit theaters on March 13, 2026.

It remains unknown if she will be attending the premiere for Reminders of Him.

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Mattel Launches First-Ever Barbie With Autism

Updated Jan 13, 2026 | 11:12 AM IST

SummaryMattel has launched its first Barbie with autism, expanding its inclusive Fashionistas range. Created with the Autistic Self Advocacy Network, the doll reflects autistic experiences through design features like averted gaze, flexible limbs, fidget toy and headphones. The move highlights growing representation of disabilities in Barbie’s evolving universe worldwide today globally.
Mattel Launches First-Ever Barbie With Autism

Credits: Mattel

Barbie. A name too familiar for everyone growing up, now Mattel Studio has launched its first autistic Barbie. This is after Greta Gerwig's 2023 blockbuster movie that introduced the concept of diverse characters of Barbie, that Mattel launched its first Barbie with type 1 diabetes. The studio is definite about creating a diverse range of Barbie character, as an animated Barbie film too is in the development.

Why Is The Launch Of Autistic Barbie Important?

Autistic Barbie is the latest addition to Barbie's Fashionistas range, which is designed so more children can "see themselves in Barbie". The Barbie is created in collaboration with the US charity the Autistic Self Advocacy Network. The Barbie is designed to represent the ways autistic children may have experienced, including the way they communicate.

Barbie With Autism: What Are Her Features?

Barbie With Autism

The Barbie's eyes gaze slightly to one side, which could represent how some autistic people avoid direct eye contact. The Barbie also comes with completely bendable elbows and wrists, which enables her repetitive physical movements such as stimming and hand-flapping that help people with autism to process sensory information, or even express excitement.

She also holds a pink fidget spinner on her finger, which helps her reduce her stress, wears noise-cancelling headphones, also in pink, to reduce sensory overload, and carries a pink tablet with symbol-based augmentative and alternative communication buttons on its screen that helps with her everyday communication.

Barbies earlier came in one-size-fit-all, often lacking the diversity and representation, this Barbie, however, wears a loose-fitting purple pinstripe A-line dress. This has minimized fabric to skin contact, and her shoes have flat soles that promotes stability and ease of movements.

Read: Hundreds Of US Children Have Type 1 Diabetes, Now Their Barbie Has It Too

Barbie's Representation Matters

The first Barbie came in 1959, and until 2019, there were no dolls with disabilities. Now, there are Barbies with diabetes, blind dolls, and Barbies with wheelchairs, Down syndrome, prosthetic limb, vitiligo, and hearing aids. There is also a Ken doll with a prosthetic leg, and another one who uses a wheelchair with a ramp, and one with hearing aids.

Jamie Cygielman, the global head of dolls at Mattel while announcing the autistic Barbie said, "Barbie has always strived to reflect the world kids see and the possibilities they imagine, and we’re proud to introduce our first autistic Barbie as part of that ongoing work. The doll helps to expand what inclusion looks like in the toy aisle and beyond because every child deserves to see themselves in Barbie."

She also added: “We engaged with the autistic community throughout the design process, always mindful that autism is experienced differently by every individual and is not always visible. The elements of this doll reflect how some people on the spectrum may experience and express the world, and we hope that by partnering with influential voices within the community, Barbie can continue to showcase a broader range of authentic experiences.”

What Is Autism?

As per the American Psychiatric Association, ASD is a complex developmental condition involving persistent challenges with social communication, restricted interests and repetitive behavior. While autism is considered a lifelong condition, the need for services and supports because of these challenges varies among individuals with autism.

As per the Centers for Disease Control and Prevention, an estimated one in 36 children have been identified with ASD.

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