Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.

What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.

Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.

1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.

2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.

3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.

4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.

5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.

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Donald Trump, the oldest president in US history, has come under increased scrutiny after turning 80 this year. The president has frequently been seen with swollen ankles and bruises on his hands, though the White House maintains he is in "excellent health."

Several doctors have also raised concerns about Trump's physical and mental health, citing instances where he appeared to fall asleep during White House meetings and international summits, as well as verbal fumbles and slurred speech.

A new book, Regime Change: Inside the Imperial Presidency of Donald Trump, claims the president's medical condition is one of the administration's most tightly controlled areas of information. Written by New York Times White House correspondent Maggie Haberman and investigative reporter Jonathan Swan, the book is based on more than 1,000 interviews conducted over three years.

Book Claims Trump Changed Routine Due to Age

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According to the authors, Trump struggles with his hearing and began moving meetings from the East Wing to the Oval Office because of better acoustics. The change also allowed him to remain seated during lengthy meetings.

The book says some aides privately felt Trump was "beginning to seem old to them," pointing to "moments of fatigue" and a "cupped hand" behind his ear.

Questions Over Transparency on Trump's Health

Speaking to Kaitlan Collins on CNN's The Source, Swan said Trump's health is "very well concealed" from the public.

"I'm not even sure that his most senior aides have a clear picture of his health, about all the aspects of his medical reports," Swan said.

Trump reportedly spent three hours at Walter Reed National Military Medical Center on May 26, where he was examined by 22 specialists, compared with 14 doctors during his previous medical check-up

"We have no indication of who those specialists are or what their specialties are," Swan said. "They haven't released all the imaging results."

According to CNN medical expert Jonathan Reiner, Trump's medical examination by 22 specialists "is an extraordinary number."

But the White House has continued to insist Trump remains sharp and energetic.

Book Describes Shift in Trump's Schedule

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According to the Daily Mail, the book claims Trump now prefers seated events, shorter public appearances and staying close to the White House.

The authors describe Trump in his second term as a "homebody," compared with his extensive travel during the 2024 campaign.

"He had never been a big sleeper, but now it seemed to his staff that he was sleeping even less, keeping stranger hours than he had in his first term," the authors wrote.

They added that Trump would often spend the early hours watching television, talking on the phone and posting on Truth Social.

White House Rejects the Claims

The White House dismissed the book's claims.

"President Trump's sharpness, unmatched energy, and historic accessibility stand in stark contrast to what we saw during the last administration when Democrats and the legacy media intentionally covered up Joe Biden's serious mental and physical decline from the American people," spokesperson Davis Ingle told the Daily Mail.

"President Trump is the sharpest and most accessible President in American history who is working nonstop to solve problems and deliver on his promises."

Andhra Pradesh is set to launch a Rare Disease Policy, aligned with the National Policy for Rare Diseases (NPRD), 2021, to improve diagnosis, treatment, and financial support for patients living with rare diseases.

The proposed policy will provide free diagnostic tests, specialized treatment, and financial assistance to affected families, Health Minister Y. Satya Kumar Yadav announced while addressing the Rare Diseases Care and Draft Policy Consultation at Dr NTR University of Health Sciences.

What's Included in Andhra Pradesh's Rare Disease Policy?

As part of the proposed policy, the state government plans to:

• Establish referral cents for rare diseases in Kurnool, Tirupati, and Visakhapatnam.
• Explore designating a government hospital as a Centre of Excellence for rare disease treatment.
• Create a state registry for diseases identified by the Indian Council of Medical Research (ICMR) to better understand the disease burden.
• Introduce universal newborn (neonatal) screening to enable early detection of rare diseases.
• Mobilize donor support to help patients meet the high cost of treatment.

The minister said the government is committed to ensuring access to quality healthcare for rare disease patients regardless of their financial status. He also stressed the importance of increasing public awareness to facilitate early diagnosis and timely intervention.

Also read: How AI Is Transforming Early Diagnosis of Rare Diseases

Further, to improve access to treatment, the state will hold a meeting with pharmaceutical companies in the first week of July to discuss the production, availability, and distribution of medicines for rare diseases.

The government also plans to encourage the pharmaceutical industry to provide financial and other support to patients.

Health Secretary S. Suresh Kumar said integrating rare disease patients with the Ayushman Bharat Digital Mission would improve treatment tracking and continuity of care. NGOs, caregivers, patients, and medical experts participating in the consultation welcomed the government's initiative and offered recommendations for the draft policy.

What Is the National Policy for Rare Diseases (NPRD)?

The National Policy for Rare Diseases (NPRD), 2021, was introduced to improve access to diagnosis, treatment, and financial assistance for patients with rare diseases.

The policy classifies rare diseases into three categories:

• Diseases that can be treated with a one-time curative intervention.
• Diseases requiring long-term or lifelong treatment.
• Diseases for which effective treatment is still under research.

Under the Rashtriya Arogya Nidhi (RAN) scheme, eligible patients can receive financial assistance of up to Rs 50 lakh for specified rare diseases covered under the policy.

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What Is a Rare Disease?

The World Health Organization (WHO) defines a rare disease as a chronic, often debilitating or life-threatening condition affecting one or fewer people per 1,000 population.

According to the WHO's International Classification of Diseases (ICD-11), more than 5,500 rare diseases have been identified, while globally there are an estimated over 7,000 distinct rare diseases affecting more than 300 million people.

In India, a disease is generally considered rare if it affects fewer than one in 2,500 people. Most rare diseases are genetic and are frequently misdiagnosed because of limited awareness, delayed diagnosis, and inadequate access to specialized care.

According to estimates by the Foundation for Research on Rare Diseases and Disorders, more than 70 million Indians are living with rare diseases. Common examples include Gaucher disease, Duchenne muscular dystrophy, and lysosomal storage disorders.

Despite affecting relatively small numbers individually, rare diseases collectively represent a significant public health challenge due to limited treatment options, delayed diagnosis, and the high financial burden on patients and their families.

Europe is enduring an unprecedented June heatwave, with temperatures reaching as high as 43.8°C and several countries breaking national records. The extreme weather has forced authorities to issue red alerts, restrict public activities, deploy cooling centers, limit alcohol sales and warn of worsening health risks.

France, Spain and the UK Break Temperature Records

France has been among the worst-hit countries. On June 24, it recorded its hottest day on record, with an average national temperature of 30.0°C, surpassing previous records set in July 2019 and August 2003, according to Météo-France. Temperatures peaked at 43.8°C in the western town of Pulluau, while overnight temperatures also set a new national record.

A record 58 French departments were placed under the highest-level red alert as officials warned of an elevated risk of forest fires amid worsening drought conditions. Forty people reportedly died in drowning accidents during the intense heat, UN News reported.

Spain also recorded its hottest June days on record on June 23 and 24, with temperatures exceeding 40°C in several locations.

In the UK, the Met Office issued a red extreme heat warning and reported a provisional June record of 36.1°C at Gosport in southern England.

Germany issued widespread red alerts, including for Bonn, Frankfurt and Cologne, while Swiss cities such as Geneva, Basel and Zurich were also placed under red alert.

WMO Warns of More Extreme Heat

Also read: Heatwave Linked To 212 Deaths In Spain: How Does Heat Impact Health?

According to the World Meteorological Organization (WMO), the heatwave is expected to spread across Western, Central and Southern Europe over the next two weeks. The agency said temperatures are forecast to remain between 3°C and 10°C above average, with daily highs exceeding 35°C across many areas and locally crossing 40°C.

The WMO also warned of more frequent "tropical nights," when temperatures remain above 20°C overnight, preventing the body from recovering from daytime heat.

Hospitals Under Pressure, Paris Restricts Alcohol Sales

The worsening conditions have disrupted healthcare services, with media reports saying hospitals have had to postpone critical imaging scans after sensitive equipment overheated. Cities have also opened emergency cooling centers to protect vulnerable residents.

In Paris, authorities have announced temporary bans on public alcohol consumption and takeaway alcohol sales to ease pressure on hospitals. Public drinking will be prohibited from noon to 7 a.m. over the weekend, while takeaway alcohol sales will be banned between 6 p.m. and 7 a.m. Licensed bars and restaurants are exempt.

French Prime Minister Sébastien Lecornu said the country's highest health alert level had been activated to boost hospital staffing and protect vulnerable people.

"We are reaching a saturation point in hospital facilities," said Paris police chief Patrice Faure, while speaking to local media.

Faure has also asked organizers of the Pride march and the Solidays music festival to cancel their events because of the continuing heatwave.

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Formula 1 Declares Heat Hazard

The extreme temperatures have also reached the sporting world. Formula 1's governing body, the FIA, has declared another "heat hazard" ahead of the Austrian Grand Prix weekend at Spielberg's Red Bull Ring, triggering additional measures to protect drivers, teams and spectators.

"Europe's savage heatwave has the fingerprints of the climate crisis all over it", said United Nations climate chief Simon Stiell. He has called for "a faster shift to renewables, protecting forests and boosting climate resilience".