World Cancer Day: The 5 Deadliest Cancers & Key Risk Factors You Should Know

Updated Feb 4, 2025 | 09:48 PM IST

SummaryWhat makes cancer the deadliest depends upon how many people have it and what percentage of those people survive.
5 Deadliest Cancer

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Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.

What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.

Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.

1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.

2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.

3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.

4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.

5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.

ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?

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Uganda On Alert Over Suspected Marburg Virus Outbreak

Updated Jul 1, 2026 | 04:00 PM IST

SummaryUganda has formally reported a case of Marburg virus disease to the World Health Organization. While the country is yet to make the outbreak public, the US Embassy in Kampala issued a health alert about the viral hemorrhagic fever.
Uganda on Alert Over Suspected Marburg Virus Outbreak

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Even as Uganda works to contain what is already the third-largest Ebola outbreak on record, centred in neighbouring Democratic Republic of Congo (DRC), the country is now facing the risk of the Marburg virus, another deadly filovirus disease.

Media reports have indicated a possible Marburg virus case in Uganda, although the country has not yet publicly declared an outbreak.

Uganda Reports Case To WHO

Uganda, however, formally reported a case of Marburg virus disease to the World Health Organization (WHO) on June 30, according to a STAT News report.

On June 29, the US Embassy in the Ugandan capital, Kampala, also issued a health alert regarding a possible case of Marburg virus disease in the country.

"The US Embassy is aware there are reports of a potential case of Marburg Virus Disease, a viral hemorrhagic fever, in western Uganda," the embassy said in its advisory.

The alert was issued as a Level 4 travel advisory, warning Americans not to travel to Uganda.

Dual Threat May Complicate Response

Also read: WHO Issues First Clinical Care Guidelines On Ebola And Marburg Disease

Uganda has extensive experience managing outbreaks of viral hemorrhagic fevers. The country last reported a Marburg virus outbreak in 2017, when there were four cases and three deaths.

However, responding to a potential Marburg outbreak while simultaneously battling Ebola could complicate public health efforts.

Both Ebola and Marburg virus disease are viral hemorrhagic fevers caused by closely related filoviruses. So far, Uganda has reported a total of 20 cases of the rare Bundibugyo species of Ebola, including two deaths. Of these, 15 cases were imported from the Democratic Republic of Congo.

What Is Marburg Virus?

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Marburg virus disease belongs to the same virus family as Ebola and has a case fatality rate that has varied widely across outbreaks.

The virus is primarily carried by fruit bats and can spread to humans through prolonged exposure to infected bats or contaminated environments. Once a person is infected, the virus spreads from person to person through direct contact with the blood, bodily fluids, or contaminated surfaces and materials used by infected individuals.

Common Signs And Symptoms

Marburg virus disease typically begins with a sudden onset of high fever, severe headache and muscle pain. Other common symptoms include diarrhea, vomiting, abdominal pain and weakness.

In severe cases, patients may develop internal and external bleeding, organ failure and shock, which can be fatal.

There is currently no approved specific treatment or vaccine for Marburg virus disease. However, supportive care significantly improves survival, and several vaccines, antiviral drugs and immune therapies are under development, according to the World Health Organization (WHO).

History Of Marburg Virus

According to the WHO, Marburg virus disease has killed between 24 per cent and 88 per cent of infected patients in previous outbreaks, depending on the virus strain and the quality of medical care available.

The virus was first identified in 1967 after simultaneous outbreaks occurred in Marburg and Frankfurt in Germany, and Belgrade in present-day Serbia. A total of 31 people were infected and seven died.

The outbreaks were traced to African green monkeys imported from Uganda for laboratory research. Fruit bats are now recognized as the natural reservoir of the virus, although other animals can also become infected.

Past outbreaks have been reported in countries including Angola, the Democratic Republic of Congo, Equatorial Guinea, Ghana, Kenya, South Africa, Uganda and Zimbabwe.

Outside Africa, only a handful of Marburg cases have been reported. Two fatal cases occurred in travelers who had visited bat-inhabited caves in Uganda—one in Europe and one in the United States.

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Why Has ISA Asked Doctors & Hospitals To Stop Prescribing Themis Spinal Anaesthesia?

Updated Jul 1, 2026 | 03:00 PM IST

SummaryAfter several suspected adverse events surfaced, the Indian Society of Anaesthesiologists has directed healthcare professionals, hospitals and others facilties to stop using Themis Hyperbaric Bupivacaine and segregate and isolate its stock until further notice.
ISA Issues Advisory To Stop Prescribing Themis Spinal Anaesthesia

Credit: AI-generated image

The Indian Society of Anaesthesiologists (ISA) has issued an urgent advisory asking anaesthesiologists and hospitals across the country to immediately stop administering Hyperbaric Bupivacaine manufactured by Themis for spinal anaesthesia until further notice.

Why Has ISA Issued This Advisory?

Themis Hyperbaric Bupivacaine is commonly administered as a spinal anaesthesia. According to the ISA and the Anaesthesia Patient Safety Association (APSA), the anaesthesia resulted in several suspected adverse events.

These reports were significant enough to warrant an immediate nationwide safety alert, even though the exact cause and frequency of the adverse events have not been revealed yet.

However, according to Medical Dialogues, the Indian Society of Anaesthesiologists has suspected that the adverse incidents linked to Themis Hyperbaric Bupivacaine were reported at Apollo Hospitals and Yashoda Hospitals. They also said that Adverse Drug Reactions (ADRs) related to the drug have been reported, and an investigation is underway.

The associations also stressed that the advisory is strictly precautionary and does not imply that the drug is defective or that Themis is responsible for any negligence or unethical practices.

Also read: National Doctors' Day 2026: Stronger Protection Against Violence In Healthcare Need Of The Hour, Say Doctors

What Does The Advisory Say?

Apart from stopping the administration of Themis Hyperbaric Bupivacaine, the advisory has also asked hospitals and healthcare facilities to:

  • Identify, segregate, and isolate existing stock of Themis Hyperbaric Bupivacaine from clinical use.

  • Switch to alternative approved brands of hyperbaric bupivacaine.

  • Preserve details like batch number, manufacturing date, expiry date, and storage conditions.

  • Report any suspected adverse events related to the drug to APSA and the relevant regulatory bodies.

Dr Sherry Mathews, President of the Hyderabad Metro City Branch of the Indian Society of Anaesthesiologists, said, “This is a precautionary advisory issued in the interest of patient safety. Reports of serious adverse events have been received from multiple hospitals, and until the investigation is completed, we have advised doctors to stop using the product.”

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A separate notice issued by the ISA's Hyderabad Metro City Branch directed consultants, resident doctors, anaesthesia technicians and operation theatre staff to immediately stop the use of Themis Bupivacaine for spinal anaesthesia.

It also said that no ampoules of the product should be used for neuraxial administration until an official clearance is issued. It added that any inadvertent use must be reported to the head of the department without fail.

The authorities are currently investigating these suspected adverse reactions, particularly their nature and association with the drug.

About Themis Hyperbaric Bupivacaine

Themis Hyperbaric Bupivacaine, marketed under brand names like Bupicain Heavy, is manufactured by Themis Medicare Limited, a 53-year-old Indian pharmaceutical company.

It contains Bupivacaine hydrochloride 0.5% (5 mg/mL), a local anaesthetic. It also contains Dextrose, which makes the solution hyperbaric (heavier than cerebrospinal fluid), which helps anaesthesiologists control how the anaesthetic spreads through the spinal canal.

Hyperbaric bupivacaine is commonly used for:

  • Caesarean sections

  • Orthopaedic surgeries involving limbs in the lower half

  • Hip and knee surgeries

  • Urological procedures

  • Gynaecological surgeries

  • Hernia surgeries

  • Other surgeries below the umbilicus

Hyperbaric bupivacaine is widely trusted for spinal anaesthesia globally. Many pharmaceutical companies manufacture it. The concern raised by the Indian Society of Anaesthesiologists is not against the drug, but about one manufacturer's production.

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Times Network India Health Awards 2026 Honors Pioneers In Healthcare Workers

Updated Jul 1, 2026 | 01:42 PM IST

SummaryThe Times Network India Health Summit 2026 – South Edition featured renowned doctors, policymakers, hospital leaders, researchers and healthcare innovators. Discussions also covered preventive healthcare, artificial intelligence, women's health, public health policy and medical innovation.
Times Network India Health Awards 2026 Honors Pioneers In Healthcare Workers

Credit: Times Network

The Times Network India Health Summit 2026 – South Edition, held on June 20 in Hyderabad, honored the outstanding contributions of doctors and innovations across the Indian healthcare sector.

The event brought together leading voices from government, medicine, research, and the healthcare industry to discuss the future of India's healthcare system.

Across three panel discussions, experts deliberated on the growing burden of obesity and anemia in the country, the role of artificial intelligence in healthcare and whether AI could outpace doctors, as well as the increasing incidence of violence against doctors and healthcare workers.

The summit featured renowned doctors, policymakers, hospital leaders, researchers and healthcare innovators. Discussions also covered preventive healthcare, artificial intelligence, women's health, public health policy and medical innovation.

The event was powered by Tamashii, with Gigglu as the associate partner, BMW Krishna Automotive as the automobile partner, Sumadhura as the real estate partner, and VOH (Voice of Healthcare) as the knowledge partner.

Also read: Times Network Health Summit 2026: Ignoring Heavy Menstrual Bleeding Can Lead to Anemia, Says Top Gynecologist

Times Network India Health Awards 2026 Winners

S.NoAward CategoryAward Winner Name
1Eminent Excellence in Functional Neuro Surgery (Telangana)Dr Dhanunjaya Rao - Apollo Hospitals
2Eminent Excellence in Robotic Joint Replacement Surgery (Telangana)Dr Vikram Byre - Yashoda Hospitals
3Legendary Excellence in Joint Replacement Surgeries (Telangana)Dr K Sudhir Reddy - Landmark Hospitals
4Legendary Excellence in Internal Medicine & Intensive Care (Telangana)Dr Rajib Paul - Apollo Hospitals
5Centre of Excellence in Varicose VeinsAVIS Vascular Center
6Legendary Excellence in Neurosurgery & Brain Stroke Prevention Public Health Services (Telangana)Dr Uday Goutam - Goutam Neuro Care
7Outstanding Philanthropic Contribution to Hearing Impairment Rehabilitation & InclusionSAHI (Society to Aid the Hearing Impaired)
8Centre of Excellence in Advanced Fertility Treatments (Telangana)Hegde Fertility
9Lifetime Achievement Award in Gastrointestinal & Minimally Invasive Surgery (Telangana)Dr G V Rao - Director AIG Hospitals
10Best Emerging Multi Specialty Hospital (Telangana)Sindhu Hospitals
11Centre of Excellence in Advanced Dentistry (Khammam)Sri Srinivasam Dental Hospital (Khammam)
12Centre of Excellence in Advanced Personalized Orthopedic Care (Telangana)My Ortho Centre
13Legendary Excellence in Dental Implants (Telangana)Dr Venkat Ratna Nag - The Dental Specialists
14Legendary Excellence in Advanced Otology (Telangana)Dr Jaswinder Singh Saluja - Apollo Hospitals
15Excellence in Robotic & Minimally Invasive Gynecological Surgery (Telangana)Dr T Rajeshwari Reddy – Continental Hospitals
16Eminent Excellence in Transplant Pulmonology (Telangana)Dr Tapaswi Krishna - Yashoda Hospitals
17Legendary Excellence in Precision Eye Surgery (Telangana)Dr Sangeeta Das - Malla Reddy Hospital
18Excellence in Agentic AI for Clinical DiagnosticsNeurologic.AI
19Centre of Excellence in Advanced Clear Aligner & Smile Design Treatments (Telangana)PARK Dental Care
20Eminent Excellence in Surgical Oncology & Robotic Surgery (Telangana)Dr Ajay Chanakya Vallabhaneni
21Lifetime Achievement in Women's Healthcare & Maternal ExcellenceDr Evita Fernandez - Fernandez Hospitals
22Best Emerging Hospital in Vascular & Plastic Surgery (Telangana)IKIGAI Hospitals
23Emerging Excellence in Voice & Airway Disorders Management (Telangana)Dr Madhav Koka - Apollo Hospitals
24Legendary Excellence in Advanced Proctology & Anal Canal Surgery (Telangana)Dr Sanjeev Singh Yadav - EPIC International Hospital
25Lifetime Achievement Award in Global Oncology ExcellenceDr Nori Dattatreyudu
26Excellence in Advanced Medical Care & InnovationAJ Hospital & Research Centre
27Visionary Excellence in Robotic Laparoscopic SurgeryDr Rooma Sinha - Apollo Hospitals

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