World Cancer Day: The 5 Deadliest Cancers & Key Risk Factors You Should Know

Updated Feb 4, 2025 | 09:48 PM IST

SummaryWhat makes cancer the deadliest depends upon how many people have it and what percentage of those people survive.
5 Deadliest Cancer

Credit: Canva

Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, and go beyond their usual boundaries to invade adjoining parts of the body. According to the World Health Organization (WHO), it is the second most common cause of death globally, accounting for millions of deaths every year. Lung, prostate, colorectal, stomach and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, cervical and thyroid cancer are the most common among women. However, these are not necessarily the deadliest forms of cancer.

What makes cancer the deadliest depends upon how many people have it and what percentage of those people actually survive. Cancer researchers determine this on the basis of five-year relative survival. This is the percentage of people who are expected to survive the effects of a given cancer, excluding their risk of other possible causes of death, for five years past a diagnosis. It is also important to note that what makes cancer really deadly is that practically no cure for it. A cure for cancer would imply that there are no cancerous cells remaining in the body.

Here are the 5 deadliest cancers in the U.S., according to SEER five-year relative survival data for cases diagnosed between 2014 and 2020.

1. Pancreatic cancer occurs when cells in your pancreas, a gland in your abdomen that aids digestion, mutate and multiply out of control, forming a tumour. Major risk factors include smoking, obesity, diabetes, chronic pancreatitis, certain genetic mutations and environmental chemical exposure.

2. Esophageal cancer develops in the oesophagus, which is the tube that connects your throat to your stomach.

3. Liver cancer and intrahepatic bile duct cancer originate in the liver or bile ducts, often linked to hepatitis infections, heavy alcohol use, obesity, and aflatoxin exposure.

4. Lung and bronchus cancer primarily caused by smoking, secondhand smoke, and environmental pollutants, affects the lungs and airways, making it the leading cause of cancer death in the US.

5. Acute myeloid leukaemia (AML) is an aggressive blood and bone marrow cancer that progresses rapidly, often linked to genetic mutations, radiation exposure, and certain chemicals.

ALSO READ: Why Are Lifestyle Factors Making Millennials Vulnerable To Cancer?

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Ebola Outbreak: Rare Bundibugyo Strain Confirmed In DR Congo And Uganda

Updated May 16, 2026 | 02:58 PM IST

SummaryBundibugyo ebolavirus was first isolated during an outbreak of hemorrhagic fever in Uganda in 2007. There are no vaccines or specific treatments approved to prevent or treat the Bundibugyo strain.
Ebola Outbreak: Rare Bundibugyo Strain Confirmed In DR Congo And Uganda

Credit: iStock

Health officials at the Africa Centres for Disease Control and Prevention (Africa CDC) today confirmed that the current Ebola outbreak in the Democratic Republic of the Congo and Uganda is being caused by the rare Bundibugyo strain.

Bundibugyo ebolavirus was first isolated during an outbreak of hemorrhagic fever in Uganda in 2007. There are no vaccines or specific treatments approved to prevent or treat the Bundibugyo strain.

Preliminary laboratory results from the Institut National de Recherche Biomedicale (INRB) detected Ebola virus in 13 of 20 samples tested with the Bundibugyo Virus.

"Africa CDC is actively collaborating with health authorities in DRC, Uganda, and regional partners to deliver a coordinated response to confirmed Ebola Virus Disease cases linked to the Bundibugyo strain," the Africa CDC said in a statement.

"Rapid laboratory testing, contact tracing, cross-border surveillance, and enhanced infection prevention measures are already deployed to protect communities and stop the spread," it added.

Ebola Outbreak: Cases And Deaths

As of the latest update from DRC, approximately 246 suspected cases and 65 deaths have been reported, mainly in Mongwalu and Rwampara health zones.

Four deaths have been reported among laboratory-confirmed cases.

Suspected cases have also been reported in Bunia and are pending confirmation. These figures remain provisional and are being validated through laboratory confirmation, line-list harmonization, contact identification, and epidemiological investigation.

Also read: Ebola Resurfaces In Eastern DR Congo In 17th Outbreak, Claims 65 Lives: All You Need To Know

Ebola Bundibugyo Virus Kills Ugandan Man

Uganda’s Ministry of Health, in a statement, reported a confirmed Ebola Bundibugyo Virus Disease case in a 59-year-old Congolese male who was admitted to Kibuli Muslim Hospital on May 11 and died on May 14.

The country's officials reported the case as imported from DRC and have indicated that no local case has yet been confirmed.

Africa CDC noted that it remains concerned by the urban context of Bunia and Rwampara, with intense population movement, insecurity, mining-related mobility in Mongwalu, gaps in contact listing, infection prevention and control challenges, and the proximity of affected areas to Uganda and South Sudan.

What Is Bundibugyo Virus Disease?

Bundibugyo virus disease is a rare and deadly illness that has caused outbreaks in several African countries in the past.

  • It is distinctly different from other known ebolaviruses like the Zaire ebolavirus or Sudan ebolavirus. The 2007 outbreak, where Bundibugyo was detected for the first time, resulted in over 100 cases and was officially declared over in early 2008.
  • According to the US CDC, the Bundibugyo strain is spread by contact with the blood or body fluids of a person who is infected with or has died from BVD.

    It is also spread by contact with contaminated objects (such as clothing, bedding, needles, and medical equipment), or by contact with animals, such as bats and nonhuman primates, that are infected with BVD.

    Symptoms include fever, headache, muscle pain, weakness, diarrhea, vomiting, stomach pain, and unexplained bleeding or bruising (a late stage of illness).

    Read More: National Dengue Day 2026: India Reports 6,927 Cases And 10 Deaths In 2026

    Ebola Outbreak: Here's How To Prevent

    The US CDC advised people to avoid:

    • contact with people who have symptoms such as fever, muscle pain, and rash
    • contact with blood and other body fluids or objects that are contaminated with them
    • visiting healthcare facilities in the affected areas for nonurgent medical care or for non-medical reasons. Avoid visiting traditional healers in the affected areas
    • contact with dead bodies or items that have been in contact with dead bodies
    • participating in funeral or burial practices that involve touching the body of someone who has died
    • contact with bats, forest antelopes, nonhuman primates (e.g., monkeys, chimpanzees, gorillas), and blood, fluids, or raw meat from these or unknown animals.
    • going into areas where bats live, such as mines or caves.

    In case of infection, the CDC advises:

    • Monitoring for symptoms of BVD while in the outbreak area and for 21 days after leaving.
    • If you develop fever, headache, muscle pain, weakness, diarrhea, vomiting, stomach pain, and unexplained bleeding or bruising (a late stage of illness)
    • Isolate immediately
    • Do not travel.
    • Contact local health authorities

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    Ebola Resurfaces In Eastern DR Congo In 17th Outbreak, Claims 65 Lives: All You Need To Know

    Updated May 16, 2026 | 09:28 AM IST

    SummaryWhile tests are being carried out to identify the strain of the virus, early indications suggest the strain is not the Zaire variant, which has been responsible for several previous outbreaks in the country, the health officials said.
    Ebola Resurfaces In Eastern DR Congo In 17th Outbreak, Claims 65 Lives: All You Need To Know

    Credit: AI generated image

    Even as the world is still grappling with the news of a hantavirus and two separate norovirus outbreaks, the Africa Centres for Disease Control and Prevention (Africa CDC) today confirmed that the Ebola virus has resurfaced in eastern Democratic Republic of the Congo for the 17th time.

    In a statement, the Africa CDC reported that there are 246 suspected cases and 65 deaths, mainly in the mining areas of Mongwalu and Rwampara, about 100 kilometers north of the provincial capital, Bunia.

    While tests are being carried out to identify the strain of the virus, early indications suggest the strain is not the Zaire variant, which has been responsible for several previous outbreaks in the country, the health officials said.

    The Ebola Zaire strain was prominent in Congo’s past outbreaks, including the 2018 to 2020 outbreak in the eastern region that killed more than 1,000 people.

    Ebola: 17th outbreak in DR Congo

    Ebola was first discovered in 1976 in the DR Congo. This is the 17th outbreak of the deadly viral disease in the country.

    As per preliminary tests conducted at the Institut National de Recherche Biomédicale (INRB) in the country's capital, Kinshasa, the Ebola virus has been detected in 13 of 20 samples analysed, following consultations with DR Congo's Ministry of Health and National Public Institute.

    Of the 65 deaths, four were reported among lab-confirmed cases, Africa CDC said.

    Additional suspected cases have also been reported in Ituri's provincial capital, Bunia, a densely populated urban centre near the borders with Uganda and South Sudan, raising fears of regional transmission.

    All affected communities and at-risk areas have been advised to follow guidelines from the national health authorities.

    Also read: More Americans Exposed To Hantavirus; 41 Under Monitoring, Says CDC

    What Is Ebola Virus Disease?

    As per the WHO, Ebola virus disease (EVD) is a rare but severe illness in humans and is often fatal.

    People can get infected with the virus if they touch an infected animal when preparing food, or touch body fluids of an infected person, such as saliva, urine, feces, or semen, or things that have body fluids of an infected person, like clothes or sheets.

    How Does Transmission Work?

    Read More: Another Norovirus Outbreak Confirmed Aboard Cruise Ship In France; Over 1,700 People Trapped

    Ebola enters the body through cuts in the skin or when one touches their eyes, nose, or mouth. Early symptoms include fever, fatigue, and headache.

    It is a highly infectious and transmissible disease; in fact, there have been cases of healthcare workers who have frequently been infected while treating patients with suspected or confirmed Ebola. This occurs through close contact with patients when infection control precautions are not practiced strictly.

    Cases of people conducting burial ceremonies, involving direct contact with the body of the deceased, can lead to the transmission of Ebola. Even after the long suffering and recovery, there is a possibility of sexual transmission. Pregnant women who get acute Ebola and recover may still carry the virus in their breastmilk or in pregnancy-related fluids and tissues.

    Symptoms include:

    • feeling tired
    • headache
    • muscle and joint pain
    • eye pain and vision problems
    • weight gain
    • belly pain and loss of appetite
    • hair loss and skin problems
    • trouble sleeping
    • memory loss
    • hearing loss
    • depression and anxiety.

    Is There Any Vaccine for Ebola?

    According to the WHO, there are two vaccines against the Ebola virus. But both the Merck-developed Ervebo vaccine, administered in one dose, and Johnson & Johnson-developed Zabdeno and Mvabea vaccine, administered in a two-dose regimen, target Zaire ebolavirus.

    The Ervebo vaccine is recommended for use in outbreak settings and is currently the only vaccine available in the global stockpile.

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    More Americans Exposed To Hantavirus; 41 Under Monitoring, Says CDC

    Updated May 16, 2026 | 09:26 AM IST

    SummaryThe CDC said its monitoring 16 people who were not on the MV Hondius cruise ship but were passengers on an April 25 flight to Johannesburg and were exposed to someone known to have been infected
    More Americans Exposed To Hantavirus; 41 Under Monitoring, Says CDC

    Credit: AI generated image

    The hantavirus outbreak may no longer be confined to the luxury Dutch cruise ship MV Hondius, with health officials now assessing the possibility of wider exposure. Officials at the US Centers for Disease Control and Prevention (CDC) said that although no cases have been reported in the US so far, the agency is monitoring 41 people for possible exposure.

    The 41 includes the 18 people evacuated from the hantavirus-hit ship from Spain’s Canary Islands.

    Notably, of the 18 passengers evacuated, two were carried in the plane's biocontainment units out of an abundance of caution — one who tested positive and another considered a suspected case. They were quarantined at a special facility in Nebraska. The remaining 16 are being quarantined in Omaha and Atlanta.

    Speaking to CNN from a biocontainment unit at the University of Nebraska Medical Center in Omaha, Dr. Stephen Kornfeld of Oregon said he “feels wonderful” and is not experiencing symptoms.

    Spanish officials confirmed that after initially testing positive for hantavirus, Dr. Kornfeld has since tested negative twice for the disease, meaning no Americans currently have the illness, Forbes reported.

    CDC Monitoring More People

    However, an additional 16 people are being monitored by the CDC.

    The new individuals were not on the cruise ship but were passengers on an April 25 flight to Johannesburg and were exposed to someone known to have been infected, said Dr. David Fitter, who is leading the CDC response to the outbreak, according to The New York Times.

    Also read: Shocking Study Finds Andes Hantavirus Could Linger In Semen For Years, Pose Transmission Risk

    Seven other passengers from the cruise ship had disembarked on April 24 in St. Helena, an island in the Atlantic Ocean, returned to the US on commercial flights, and are being monitored by state health departments.

    As of May 14, there were no confirmed hantavirus cases in the United States, Dr. Fitter said.

    “Our job is to ensure that we are monitoring and in contact with anybody that might have been on the flight this person had taken,” Dr. Fitter told reporters. The agency is “monitoring all Americans that potentially would have been exposed, whether in the US or abroad, and we have been in contact with them,” he said.

    Hantavirus Outbreak: 11 Cases And 3 Deaths Reported

    According to the World Health Organization (WHO), 10 people have been affected by the rat-borne virus so far, of whom three have died.

    A Dutch couple is believed to have first been exposed to the virus while visiting a birdwatching site in Argentina.

    The WHO has confirmed that the Andes strain of hantavirus — the only strain known to spread from person to person — is behind the outbreak.

    While all passengers onboard the cruise have been taken care of by health authorities, the virus’ long incubation period remains a serious concern. This means that even asymptomatic individuals could potentially become infectious 6-8 weeks later.

    WHO Guidelines On Hantavirus Exposure

    The WHO recommends that people exposed to hantavirus should be:

    • Monitored actively at a specified quarantine facility
    • Monitored at home for 42 days from the last exposure
    Anyone who becomes symptomatic should be isolated and treated immediately.

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