Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

TikTok star Brooke Eby, who chronicled her life with amyotrophic lateral sclerosis (ALS), through candid, humorous and deeply personal videos, has died at 37.

Eby was diagnosed with ALS, also known as Lou Gehrig’s disease, in 2022 at age 33. ALS is a progressive neurodegenerative disease that damages the nerve cells responsible for voluntary muscle movement.

Brooke Eby Made ALS Personal

Eby became known for sharing the realities of living with ALS on social media. Her videos combined humor with candid accounts of how the disease affected her mobility, breathing, speech and daily life.

The ALS Network described her as an “extraordinary advocate, storyteller, community builder and friend” whose honesty and humor helped change how people understood ALS.

“Brooke changed the way people see ALS, but she also changed the way people living with ALS find and support one another,” said Sheri Strahl, president and CEO of the ALS Network.

Eby also used her platform to challenge the perception that ALS mainly affects older men.

“I didn’t choose ALS, but I did choose to get loud, and be irreverent about it,” Eby said after receiving an award from the ALS Network for her advocacy.

Also read: New RNA Therapy For ALS, The Disease Stephen Hawking Had: Patient With Rare Motor Neuron Disease Improves

She Documented Her ALS Progression

Eby regularly updated followers as her condition progressed.

In June 2025, she said her breathing capacity had declined significantly over six months. She also shared that she had undergone a procedure to have a feeding tube placed in her stomach.

By January 2026, Eby said she had begun experiencing bulbar symptoms, which can affect speech and swallowing. She reported trouble swallowing, speech disturbances and excess saliva.

In September 2026, she shared that her speech had deteriorated rapidly.

“In the last few weeks, people just can’t understand me at all,” she said, explaining that speaking had also begun requiring careful positioning of her body.

Eby Wanted People To Understand ALS Can Affect Anyone

In a PEOPLE essay, Eby wrote that she wanted people to understand that ALS does not discriminate by age, gender or demographic.

“I have ALS at a relatable age. Personally, I always associated this disease with older men,” she wrote. “But I could be someone’s daughter, sister, mom, girlfriend, wife.”

While much of her content was comedic, Eby also educated her audience about ALS, including how symptoms can vary and how the disease progresses.

Read More: Stanford Scientists Say The Human Brain May Be Two Separate Organs: How It Could Affect ALS & SMA Research

What Is ALS?

ALS affects motor neurons in the brain and spinal cord that control voluntary muscle movement. As these nerve cells degenerate, people can develop muscle weakness, loss of movement, difficulty speaking and swallowing, and eventually breathing problems.

ALS can begin in the limbs or with speech and swallowing problems, known as bulbar-onset ALS.

There is currently no cure for ALS, although treatments can help manage symptoms, improve quality of life and extend survival.

ALS Symptoms

Symptoms vary but can include:

• Muscle weakness
• Muscle cramps and twitching
• Muscle atrophy
• Stiffness and spasticity
• Difficulty speaking or swallowing
• Breathing difficulties
• Changes in emotional expression

Some people with ALS also develop cognitive or behavioral changes.

Eby’s social media posts gave thousands of followers a candid look at how the disease could change everyday life, while helping raise awareness about a condition that is often associated with older adults.

Raw milk is often promoted as a natural alternative to pasteurized milk. But unpasteurized milk can carry harmful bacteria, including E. coli, Salmonella and Campylobacter.

Two young girls in California — 17-month-old Brooklyn and 6-year-old Victoria — were hospitalized with severe E. coli infections after drinking raw goat milk from the same farm, ProPublica reported.

Brooklyn developed hemolytic uremic syndrome (HUS), a potentially life-threatening complication of E. coli infection, and nearly died.

Doctors suspected the raw milk was the source of the infections.

How Did Brooklyn Get Sick?

Brooklyn’s mother, Emily Marris, had been looking for an alternative to formula after breastfeeding her daughter for a year. As she could not continue breastfeeding due to a medication for chronic hip pain, she tried cow’s milk, which left Brooklyn with constipation.

Marris was then guided to raw goat milk in a Facebook group run by her chiropractor.

Members recommended it, claiming goat milk was easier to digest. The group also directed her to MoonLight Ridge Farm.

Also read: Unsafe Sleep Factors Linked To 73% Of Sudden Unexpected Infant Deaths In US: CDC

Brooklyn Developed Severe E. Coli Infection

Brooklyn drank the raw milk for about six months. But on June 2, Brooklyn suddenly began vomiting. Her condition rapidly worsened and she was transferred to Rady Children’s Hospital in San Diego.

Doctors diagnosed her with hemolytic uremic syndrome (HUS), in which blood clots damage small blood vessels and can cause kidney failure.

A stool test confirmed E. coli O157:H7. Doctors suspected the raw milk was the likely source.

Brooklyn required intensive care, including a breathing tube and dialysis. Her condition became so severe that her parents feared she would not survive. She also went into cardiac arrest three times.

E. coli can live in animal intestines and contaminate milk through fecal matter. Even a small amount can cause infection.

Victoria Also Hospitalized

Brooklyn was not the only child affected. Six-year-old Victoria, who had also consumed milk from the same farm, was treated at the same San Diego hospital for a severe E. coli infection and required blood transfusions.

There are more children suffering from severe infections after drinking raw milk. In the past two years alone, hundreds had fallen ill across nine states from drinking raw milk or eating products made with it, as social media influencers and President Donald Trump’s White House continue to promote the unproven benefits of raw milk and downplaying its risks.

Read More: Are GLP-1 Drugs Safe for Children? Study Finds Nutritional Deficiency in Nearly 17% Within a Year

What Happened to the Farm?

California regulates raw-milk sales, but ProPublica reported the farm sold unlabeled milk without the required license. However, on August 1, the Food and Agriculture Department found that the farm had sold unapproved raw milk without a CDFA license. It was not penalized, the report said.

Brooklyn Faces Long-Term Health Problems

After leaving the hospital, Brooklyn required physical therapy and experienced problems with walking and sleep. Her mother said her development had stalled.

Doctors also warned of possible long-term kidney problems and advised regular nephrology follow-up.

What Is Raw Milk?

Raw milk is milk that has not been pasteurized. Pasteurization uses heat to destroy harmful bacteria and other pathogens.

Raw-milk proponents often claim that pasteurization destroys nutrients or improves the health benefits of milk. However, experts say pasteurization does not significantly alter milk’s mineral or protein content.

Claims that raw milk improves digestion or boosts immunity have not been scientifically established.

How Does Raw Milk Become Contaminated?

Raw milk can be contaminated through:

Animals: E. coli, Salmonella and Campylobacter can enter milk through infected animals or fecal contamination.

Environment and equipment: Polluted water, dirt, manure and contaminated milking equipment can also introduce pathogens.

Raw Milk Health Risks

Raw milk can cause diarrhea, stomach cramps, nausea and fever. In some cases, infections can become severe or life-threatening.

Children, older adults, pregnant women and people with weakened immune systems are particularly vulnerable.

Certain E. coli infections can cause HUS, which may lead to kidney failure and other serious complications.

Pasteurization destroys harmful bacteria while preserving the nutritional value of milk. The FDA, CDC and American Academy of Pediatrics advise against consuming raw milk because of its foodborne infection risks.

Ten batches of medicines used for seizures, heart conditions, depression and postpartum bleeding have been withdrawn at New Delhi’s Dr Ram Manohar Lohia Hospital after quality failures and physical defects were identified.

According to The Times of India, the affected medicines include sodium valproate, spironolactone, imipramine, metoprolol and methyl ergometrine. Some batches were classified as “Not of Standard Quality” after testing, while others showed physical defects.

Which Medicines Were Recalled?

A September 14 notice from RML Hospital said three tablet batches had failed analytical testing:

• Sodium valproate gastro-resistant 200 mg
• Spironolactone 50 mg
• Imipramine 25 mg

Five injectable batches were also recalled after failing quality tests. They included:

• Adenosine
• Methyl ergometrine
• Multivitamin injection
• Pheniramine maleate
• Ascorbic acid

The hospital had separately flagged physical defects in two tablet batches, the report said.

Tablets Found In Powder Form

Also read: 2 Indians Charged In US Over Fake Ozempic Scheme: How To Spot Counterfeit GLP-1 Drugs

A September 9 notice said isosorbide mononitrate 20 mg tablets were found in powder form inside their strips.

The affected batch, ABT6711, was manufactured by Glowson India Labs in July 2026 and expires in June 2028. Departments were told to stop using and return the batch.

A similar defect was found in metoprolol 50 mg tablets from batch ABT6608, also manufactured by Glowson India Labs. The hospital ordered its withdrawal.

RML Hospital Acts On Quality Failures

RML officials said the affected medicines were recalled after test results were received, with departments instructed to stop using them and report any patient-related problems.

Some medicines were supplied by Jackson Laboratories, according to the hospital.

No severe adverse effects had been reported among patients in connection with the affected batches, officials said. The hospital has also arranged alternative medicines to prevent disruption in treatment.

“The hospital has made interim arrangements to ensure the availability of alternative medicines and avoid any disruption in patient care. The situation is being closely monitored, and all necessary measures are being taken in accordance with established drug quality and patient-safety protocols,” RML official said, TOI reported.

What Happens If You Take A Defective Medicine?

Poor quality drugs can have a severe impact on health which includes death, disease progression, drug resistance and so on.

Poor quality drugs can contain toxic ingredients or incorrect active ingredients that can lead to death. It can also make chronic and infectious diseases worse. Furthermore, these drugs can lead to drug resistance and can threaten the health of people who are consuming them.

It can also cause side effects like rashes, hive, and other health risks, leading to further increasing the health care cost, and leading to loss of income. It can also lead to people's loss of faith in the healthcare system.

What Should You Do If You Took A Recalled Medicine?

Do not stop an essential prescription medicine on your own. Check the medicine name, strength, batch number and expiry date, and contact your doctor or pharmacist if you have a recalled batch.

Seek urgent medical care for serious symptoms such as difficulty breathing, swelling, severe allergic reactions, loss of consciousness or seizures.