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Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.
The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.
Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.
Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:
Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.
Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.
Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.
One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.
Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:
"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."
Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.
The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.
Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.
One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.
Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:
"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."
He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.
With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.
As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.
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The U.S. Centers for Disease Control and Prevention is promoting a long-debunked theory, suggesting a potential link between vaccines and autism, and claiming that studies supporting this connection “have been ignored by health authorities.”
The disputed theory appeared on a revised section of the CDC’s website under “Autism and Vaccines” on Wednesday. The website now states: “The statement ‘Vaccines do not cause autism’ is not an evidence-based claim. Scientific studies have not ruled out the possibility that infant vaccines contribute to the development of autism.
However, this statement has historically been shared by the CDC and other federal health agencies within HHS to prevent vaccine hesitancy.” The agency added that the U.S. Department of Health and Human Services has “launched a thorough review of the causes of autism, including investigations on plausible biological mechanisms and potential causal links.”
It also noted, “This webpage will be updated with gold-standard science.” Prior to Wednesday, the page stated there is “no link” between vaccines and autism, and no vaccine ingredients were connected to the condition, according to archived versions cited by The Washington Post.
Another part of the site, “About Vaccines for Your Children,” last updated in August 2024, still asserts, “Scientific studies and reviews continue to show no relationship between vaccines and autism.” Dr. Demetre Daskalakis, a former CDC official who resigned earlier this year as head of the National Center for Immunization and Respiratory Diseases, criticized the changes, saying on X, “The weaponization of the voice of CDC is getting worse. DO NOT TRUST THIS AGENCY. This is a national embarrassment.” Despite the new language, the header “Vaccines do not cause autism” remains due to an agreement with Sen. Bill Cassidy (R-La.), chair of the Senate Health Committee, who cast the deciding vote to advance Health Secretary Robert F. Kennedy Jr.’s nomination to the full Senate floor.
The revisions surprised CDC staff, including those overseeing vaccine safety and autism information, leaving them blindsided, according to The Post. “We just saw it, and everyone is freaking out,” one scientist said, as per NBC News.
While the changes could undermine public confidence in vaccines, Kennedy and Trump have historically supported this theory. Both have also warned against Tylenol use during pregnancy, claiming a link to autism, despite large-scale studies disproving any connection.
Autism spectrum disorder, or autism, is a condition that affects the brain, making it challenging for some people to communicate and interact with others. Experts still don’t fully understand what causes it.
The idea that vaccines might play a role largely began with a 1998 study suggesting that the MMR (measles-mumps-rubella) vaccine—or infection with the natural measles virus—could lead to autism. Since then, numerous scientific studies have shown there is no connection between vaccines or any of their ingredients and autism.
The 1998 study itself was later discredited: the research was found to be false, the doctor responsible lost his medical license, and the journal that published the paper retracted it, acknowledging it should never have been published.
Despite strong evidence showing vaccines are safe and effective, some parents still choose to delay or skip vaccinations for their children. This can be very dangerous, as diseases like measles, which vaccines prevent, are still circulating. An unvaccinated child who contracts one of these illnesses can become seriously ill or even die and may also put others at risk.
While mild reactions like a fever or rash can occur after vaccination, the chance of a serious side effect from the MMR or other recommended vaccines is very small compared to the risks of the diseases they protect against.
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A major claim from China has sparked global curiosity and debate after a Shenzhen-based biotechnology company announced that it has developed a longevity pill capable of significantly slowing ageing.
A biotechnology company in Shenzhen, China, has caught worldwide attention by claiming to have created a pill that could dramatically slow the ageing process. According to the firm, the pill may one day help humans live up to 150 years by targeting ageing at the cellular level.
As per The Independent, Lonvi Biosciences says its formula focuses on ‘zombie cells’—aged cells that refuse to die, causing inflammation and age-related illnesses. Let’s take a closer look at the pill and explore whether this ambitious claim could be possible.
The Shenzhen-based company, part of China’s rapidly growing longevity industry, claims it has produced a pill that could theoretically stretch human life to 150 years. The formula targets so-called “zombie cells”—older cells that resist dying, leading to inflammation and disease associated with ageing. “This is not just another pill. This is the Holy Grail,” said CEO Ip Zhu, calling the capsule a breakthrough that could make extreme longevity achievable. The main ingredient comes from grape seeds and has shown in lab studies to extend lifespan in animals by delaying age-related diseases. Lonvi’s researchers suggest that taking the pill in adulthood could push life expectancy past 120, while starting from birth could surpass 150.
The pill contains procyanidin C1 (PCC1), a compound extracted from grape seeds. In experiments with mice, Lonvi claims the treatment increased overall lifespan by 9.4%, with a remarkable 64% improvement when dosing started from the very beginning. Lyu Qinghua, Lonvi’s chief technology officer, told The New York Times that reaching 150 is “definitely realistic” and could be possible “within a few years.”
China has made anti-ageing research a national priority, with President Xi Jinping reportedly discussing it with Russian President Vladimir Putin. Anti-ageing research, combined with AI and biotech, has quickly moved from niche interest to mainstream focus in the country.
A study in Nature Metabolism showed that procyanidin C1 from grape seed extract successfully extended both the lifespan and health span of mice, paving the way for future clinical trials.
Cellular senescence plays a key role in ageing, occurring when cells can no longer perform their functions. In recent years, researchers have identified drugs called senolytics, which can eliminate these senescent cells in the lab and in animal studies. This approach is an important step toward reducing age-related chronic diseases and could play a critical role in extending lifespan.
While the company’s claims have not yet been tested in human trials, scientists believe the approach holds promise for extending life. Lonvi’s researchers say the PCC1 pill can boost cellular health, delay deterioration, and maintain energy production over time. They suggest that when combined with a healthy lifestyle, the pill could help people live beyond 100, and possibly even past 120, while also reducing diseases linked to ageing.
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A cheese brand has recalled one of its products over a serious health risk. Face Rock Creamery LLC has announced a voluntary recall of its Vampire Slayer Garlic Cheddar, according to a recent notice shared by the United States Food and Drug Administration. The decision came after the FDA detected Listeria monocytogenes in the area where the cheese was packed. The cheese is being pulled from shelves due to listeria contamination, which has also been linked to recent deaths in the United States, as reported by The Independent.
Only 16 units of the affected cheese were sold at the Face Rock flagship outlet at 680 2nd St. SE, Bandon, Oregon. Shoppers can identify the recalled product by its UPC code 8 512222 00547 8, according to the FDA.
These six ounce blocks were sold between November 10 at 3:30 p.m. PT and November 13 at 3:30 p.m. PT. Although no illnesses have been confirmed so far, customers who purchased the cheese are advised to discard it or bring it back to the store for a complete refund.
The item under recall is the Vampire Slayer Garlic Cheddar with a use by date of November 4, 2026, and the UPC 8 512222 00547 8. Face Rock Creamery stated that it is committed to strict food safety practices and transparency and that it is cooperating with authorities while taking immediate action to secure its production setting, according to The Independent. As of November 18, the FDA had not received any reports of illness tied to this cheese.
The recall notice on the FDA website explains that listeria infections can be dangerous and may be fatal for young children, older adults, and individuals with weakened immunity. It also states that healthy people might experience short-term problems such as high fever, strong headache, stiffness, nausea, stomach pain and diarrhea. For pregnant women, listeria can lead to miscarriages or stillbirths.
Listeria is a bacteria found in soil, water and animals that can contaminate food and cause listeriosis, a serious infection, as per World Health Organization. It poses a higher risk for pregnant women, newborns, older adults and people with weakened immune systems because it can live and grow even at refrigerator temperatures.
People usually become sick after eating contaminated items such as soft cheeses, deli meats or unpasteurized milk. Symptoms may be mild or flu-like, but the infection can lead to dangerous problems, including meningitis.
In the United States, listeria is the third leading cause of death linked to foodborne illness and is responsible for about 260 deaths each year. Many food products have been recalled in the past few months due to listeria concerns. As per USA Today, six people have died in a multistate outbreak connected to recalled prepared pasta dishes sold at large chains including Albertsons, Kroger, Sprouts Farmers Market and Trader Joe’s.
Federal officials reported at least 27 infections across 18 states, and CNN noted that a pregnant woman lost her fetus after becoming sick.
Symptoms of listeriosis often begin with fever, chills, muscle pain, nausea or diarrhea. In more severe cases, the infection can spread beyond the digestive system and may cause intense headache, stiff neck, confusion, seizures and widespread infection that leads to organ failure. Pregnant women may have only mild flu-like signs, yet the infection can cause serious harm to the developing fetus.
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