Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

Health officials in England have confirmed that an adult with an underlying immunological condition has died from measles, marking the third measles-related death this year after two children died in June.

According to the latest figures from the UK Health Security Agency (UKHSA), England has recorded 883 confirmed measles cases between the start of the year and July 6. More than half of the cases have been reported in London, with most infections occurring in children aged 10 years and under.

All regions of England, including London (52 per cent), the West Midlands 17 per cent, and the North West 10 per cent, have now reported measles cases.

The UK was declared measles-free in 2017 but lost that status in 2019 after vaccination rates declined and outbreaks resumed.

In January, the World Health Organization (WHO) confirmed that the UK was no longer considered to have eliminated measles, citing stagnant vaccination coverage and rising case numbers.

NHS Launches Catch-Up Vaccination Drive

Also read: Experts Say US Cyclospora Parasite Outbreak Is Unusual: How To Clean Fresh Produce

In response to the surge in infections, NHS leaders have launched a nationwide catch-up campaign targeting children aged two to 11 years who have missed one or both doses of the measles, mumps and rubella (MMR) vaccine.

The program will contact around one million families whose children are not fully vaccinated.

• GPs will contact parents of children under six.
• Families with children aged six to 11 will be contacted through the NHS App, text message, email or letter.

Current figures show that 84.1% of five-year-olds in England had received both doses of the MMR vaccine during the first three months of the year—well below the 95% coverage recommended to prevent outbreaks.

"We urge all parents to ensure their children are up to date with their MMR or MMRV vaccines, giving them the best and safest protection against measles," said Dr Vanessa Saliba, consultant epidemiologist at UKHSA.

"Anyone who has missed their measles vaccines can catch up through their GP practice, whatever their age. Getting vaccinated also helps protect babies who are too young to be vaccinated and people who cannot receive the vaccine because of certain health conditions," Dr Saliba added.

What Is Measles?

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Measles (rubeola) is one of the world's most contagious viral infections. It spreads through respiratory droplets released when an infected person coughs or sneezes and can also spread by touching contaminated surfaces before touching the eyes, nose, or mouth.

Symptoms usually develop 7 to 14 days after exposure and include:

• High fever
• Cough
• Runny nose
• Red, watery eyes
• Small white spots inside the mouth (Koplik spots)
• A red rash that typically starts on the face before spreading across the body

While many people recover fully, measles can cause serious complications, including pneumonia, encephalitis (brain inflammation), hearing loss, and, in rare cases, death.

All About the MMRV Vaccine

The MMRV is a safe, live-attenuated immunizations that protect against severe viral infections. The shot combines Measles, Mumps, and Rubella, and also adds protection against Varicella (chickenpox).

According to the UKHSA, children receive:

• First dose: At 12 months, alongside MenB and pneumococcal (PCV) vaccines.
• Second dose: At 18 months, alongside the fourth 6-in-1 vaccine.

Children who miss these doses can receive a catch-up vaccination at their 3-year and 4-month appointment. The MMRV vaccine contains weakened forms of the measles, mumps, rubella, and chickenpox viruses, which stimulate immunity without causing disease.

Two MMRV vaccines are available:

• ProQuad (contains porcine gelatine)
• Priorix Tetra (does not contain porcine gelatine).

An outbreak of Cyclospora, a microscopic parasite that causes prolonged watery diarrhea, has sickened more than 1,400 people across the United States, with infectious disease experts describing the surge in cases as "definitely abnormal."

While the US Centers for Disease Control and Prevention (CDC) is still investigating the source, officials believe the outbreak is likely linked to multiple sources of contamination rather than a single food product.

Health officials in Michigan have reported 1,251 Cyclospora infections, a dramatic increase from around 170 cases recorded on June 30. The state typically reports only about 50 cases annually.

Ohio has confirmed nearly 200 cases, while New York, Illinois, Indiana, North Carolina, and Texas have also reported an increase in infections. More than 40 people have been hospitalized.

Dr. Thomas Moore, an infectious disease specialist and clinical professor of medicine at the University of Kansas School of Medicine-Wichita, described the spike as "definitely abnormal" and concerning, according to The New York Times.

Keith R. Schneider, professor of food safety at the University of Florida, noted that Cyclospora infections usually increase between May and August in the United States. However, he said the current surge—particularly in Michigan—is far beyond what is normally expected.

"Something is going on right now in that area," Schneider told The New York Times.

Experts also warned that the reported infections may represent only the "tip of the iceberg," with additional cases expected in the coming weeks, because the infection takes long to manifest.

Also read: Crusted Scabies Outbreak: UK Reports Rare Highly Contagious Skin Disease

What Is Cyclospora And How Does It Spread?

Cyclospora is a microscopic parasite that infects people after they consume food or water contaminated with human feces containing the parasite's eggs (oocysts).

Unlike many foodborne bacteria, Cyclospora infections often takes two days to two weeks or more to cause illness after exposure, making it difficult for investigators to identify the original source.

Although the illness is usually not life-threatening, it can cause prolonged diarrhea, stomach cramps, nausea, fatigue, bloating, and weight loss.

Fresh produce is the most common source of infection, though contaminated water can also spread the parasite. Health officials have not advised people to avoid fresh produce, as investigators have not yet identified the exact food responsible for the current outbreak.

Yet, previous US Cyclospora outbreaks have frequently been linked to imported fresh produce, including:

• Basil
• Cilantro
• Mesclun lettuce
• Raspberries
• Snow peas

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Handwashing Matters More Than Hand Sanitizer

Experts emphasize that proper handwashing with soap and water remains one of the most effective ways to reduce the risk of infection.

Alcohol-based hand sanitizers do not kill Cyclospora, making soap and water essential after using the bathroom and before preparing or eating food.

"This type of parasite doesn't easily go away with alcohol-based hand sanitizer. So, good old handwashing is really key here," ABC News medical correspondent Dr. Darien Sutton said.

How To Clean Fresh Produce Safely

While washing produce cannot eliminate all risk, experts say it can reduce contamination. They advised washing fruits and vegetables thoroughly under clean running water, and washing hands before and after handling fresh produce.

According to the Michigan Department of Health and Human Services, cooking produce whenever possible during an active outbreak is crucial, as heating food to at least 158°F (70°C) kills Cyclospora.

For specific produce, it suggested:

• Cilantro and basil: Separate the leaves and rinse each thoroughly under running water.
• Green onions: Trim off the roots, remove the outer layer, and rinse well.
• Snow peas: Rub the surface gently while washing under running water.
• Raspberries: Because of their delicate, uneven surface, raspberries are difficult to clean thoroughly. Cooking them in pies or jams is safer. Freezing may reduce the number of parasites but is unlikely to eliminate them completely.
• Leafy greens: If possible, choose whole heads of lettuce instead of bagged salad mixes. Discard the outer leaves and wash the remaining leaves under running water before eating.

The UK has reported an outbreak of crusted scabies, a rare and highly contagious form of scabies, prompting the temporary closure of a hospital ward in Wales.

According to the Hywel Dda University Health Board, Steffan Ward at Glangwili Hospital in Carmarthen has been temporarily closed while the outbreak is managed under established infection prevention and control measures, according to the BBC.

Health officials said all patients and staff identified as close contacts have been informed and offered treatment, even if they are not showing symptoms. Enhanced infection control measures, including monitoring, treatment of identified contacts, and specialist support, have also been put in place.

Officials added that a recent rise in scabies cases across Carmarthenshire, Pembrokeshire, and Ceredigion has contributed to outbreaks in healthcare settings. The ward will reopen once it is deemed safe under infection control guidance.

What Is Crusted Scabies?

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Scabies is a highly contagious skin infestation caused by the microscopic mite Sarcoptes scabiei. The mites burrow into the upper layer of the skin, where they lay eggs, triggering an allergic reaction that causes intense itching and a rash.

However, the crusted scabies—previously known as Norwegian scabies—is a severe form of the infestation in which the skin develops thick, crusted plaques that may crack and become inflamed, according to the US Centers for Disease Control and Prevention (CDC).

Unlike classic scabies, patients with crusted scabies may not experience severe itching or develop the typical rash, making the condition more difficult to recognize. However, they can carry up to two million mites and eggs, making them extremely contagious.

Because of the heavy mite burden, crusted scabies can rapidly spread in healthcare facilities and long-term care homes if not identified and treated promptly. It may also lead to serious complications, including secondary bacterial infections and sepsis.

Who Is Most at Risk?

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People at increased risk of developing crusted scabies include:

• Older adults
• People with weakened immune systems, including those living with HIV/AIDS
• Individuals with conditions that reduce the ability to itch or scratch, such as spinal cord injuries, paralysis, loss of sensation, or severe neurological or behavioral disorders

How Can Crusted Scabies Be Prevented?

Preventing outbreaks requires rapid diagnosis, prompt treatment, and strict infection control measures.

Health authorities recommend:

• Identifying and treating all close contacts, including household members, caregivers, and sexual partners
• Isolating affected individuals when necessary
• Washing or decontaminating bedding, clothing, and towels used by infected patients
• Maintaining strict hygiene and environmental cleaning in healthcare settings

Why Early Diagnosis Matters

Early diagnosis is critical to preventing further transmission. Since crusted scabies may not present with the classic symptoms of itching and rash, healthcare professionals play an important role in recognizing the condition.

Only a qualified healthcare provider can confirm the diagnosis and prescribe appropriate treatment. Prompt medical care helps reduce the risk of complications and prevents outbreaks in hospitals, nursing homes, and other communal settings.