Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

The White House has informed that US President Donald Trump is getting another medical and dental checkup at the end of May.

This will be his fourth publicized visit to medical experts in his second term as US President. The White House described it as "an annual physical and regular preventive care", AP reported.

Trump, who turns 80 next month, will see his doctors at the Walter Reed National Military Medical Center on May 26, the White House said in a brief statement.

The president’s health has been the subject of tremendous scrutiny — ranging from his mental state to visible bruising around his hands.

While past presidents have opted for the White House's on-site clinic, Trump went for a local dentist instead, a choice he made previously in January.

Trump — who has been frequently critical of former President Joe Biden for age-related health and fitness issues — has recently remarked how good he feels despite his years.

Earlier Monday, Trump said he feels the same as he did 50 years ago. “I feel literally the same,” he said at an Oval Office event. “I don’t know why. It’s not because I eat the best foods”, AP reported.

Last week, he joked about his exercise regimen, saying that he works out “like about one minute a day, max.”

Also read: Was Trump Sleeping During Oval Office Event? White House Reacts

Trump's Health Checkups

The first visit was reported last April, when Trump had a checkup after noticing what the White House described as “mild swelling” in his lower legs. Tests by the White House medical unit found that Trump had chronic venous insufficiency, a condition common in older adults that causes blood to pool in his veins.

During the medical exam in October, which the White House called a “semiannual physical,” he also got his yearly flu shot and a COVID-19 booster vaccine. He later told The Wall Street Journal that he underwent advanced imaging on his heart and abdomen in October as preventive screening.

The upcoming evaluation follows two other recent visits to a local dentist near his estate in Florida, where Trump often spends his weekends.

Also read: Donald Trump’s Swollen, Heavily Bruised Hands Raise Fresh Health Concerns

Experts Claim Trump's Mental Health Is Deteriorating

Read More: Fact Check: Can Ivermectin Help Treat Hantavirus?

A group of medical experts has sounded the alarm over what they’ve described as Trump’s deteriorating mental health, The Daily Beast Reported.

The three dozen medical professionals include neurologists, psychiatrists, and other physicians with extensive experience diagnosing cognitive disorders and evaluating patients.

The experts have not specifically examined Trump face-to-face. But, based on his statements and behaviors over the past year, they stated that he’s “mentally unfit” and must be removed from office “with the greatest urgency” amid the escalating tension around the world, the report said.

“It is our professional opinion that they (Trump's statements) reflect a rapidly worsening, reality-untethered, increasingly dangerous decline,” the experts said in a statement.

They also listed some of Trump’s observable serious medical issues, such as “Marked deterioration in cognitive functioning, evidenced by disorganized and tangential speech, rambling digressions, factual confusions, unexplained sudden changes of course in strategic matters, both national and international, episodes of apparent somnolence during critical public proceedings.”

In yet another video sparking concerns about US President Donald Trump’s health, he appeared to doze off during an Oval Office event on maternal healthcare.

This is not the first time Trump’s sleeping habits have sparked public discussion. His unusual late-night social media activity has frequently drawn attention online.

But the latest video shows the 79-year-old President, the oldest person elected US president, apparently falling asleep as the attendees stood behind the POTUS' chair spoke.

Also Read: Donald Trump Says Hantavirus Is 'Under Control'; Questions Grow Over CDC Research Cuts

The video immediately went viral on social media and sparked concerns around Trump's health, despite White House's assurances that he is “excellent” and fit to perform Presidential duties.

Some users on X called Trump "Sleepy Don", others said he is not physically fit to be the President.

“Today is Monday. That means Trump falls asleep at yet another high-profile event with cameras rolling," California Rep. Ted Lieu wrote. "Imagine what happens when there are no cameras. Trump is not mentally or physically fit to be President of the United States."

"Trump fell asleep with his face drooping in the Oval Office during a meeting today. This is a real video that should concern every American. He’s not fit to serve," wrote another user.

However, the White House responded angrily, stating that he was “blinking” and not asleep.

“He was blinking, you absolute moron,” the Rapid Response 47 account said.

White House Splits Shifts To Keep Up With Trump

Earlier, Susie Wiles, chief of staff to Trump, revealed how senior White House aides manage the President’s unusual sleep schedule and late-night work habits behind the scenes.

Trump’s habit of posting on Truth Social late at night and remaining active during overnight hours has long fueled curiosity about how much sleep he actually gets.

Speaking during the Independent Women’s Gala, Wiles discussed the challenges of operating in what she described as a White House that runs on “Trump time,” according to The Mirror US.

“I am not one of those people that doesn’t need sleep, I actually do very much,” Wiles, 68, said while explaining how staff members adapt to the president’s around-the-clock routine.

According to Wiles, the administration has developed an informal system to ensure staff can manage the demanding workload while still getting rest.

“I go to sleep early, and Dan Scavino, who I’m sure many of you know, is a night owl; we divide it,” she explained. “I get the early calls, and Dan gets the late calls.”

Previously, Trump himself has joked about his sleeping habits. After appearing to briefly close his eyes during a televised cabinet meeting earlier this year, he brushed off the speculation by saying the session had simply become “a little bit on the boring side.”

“I didn’t sleep, by the way,” Trump added. “I don’t sleep much.”

Experts Claim Trump's Mental Health Is Deteriorating

Also read: Fact Check: Can Ivermectin Help Treat Hantavirus?

A group of medical experts has sounded the alarm over what they’ve described as Trump’s deteriorating mental health, The Daily Beast Reported.

The three dozen medical professionals include neurologists, psychiatrists, and other physicians with extensive experience diagnosing cognitive disorders and evaluating patients.

The experts have not specifically examined Trump face-to-face. But, based on his statements and behaviors over the past year, they stated that he’s “mentally unfit” and must be removed from office “with the greatest urgency” amid the escalating tension around the world, the report said.

“It is our professional opinion that they (Trump's statements) reflect a rapidly worsening, reality-untethered, increasingly dangerous decline,” the experts said in a statement.

They also listed some of Trump’s observable serious medical issues, such as “Marked deterioration in cognitive functioning, evidenced by disorganized and tangential speech, rambling digressions, factual confusions, unexplained sudden changes of course in strategic matters, both national and international, episodes of apparent somnolence during critical public proceedings.”

While concern continues over the deadly hantavirus outbreak on the MV Hondius cruise ship, reports of more than 100 people falling ill on a Caribbean cruise with vomiting and diarrhea have also sparked alarm.

A cruise ship sailing from Florida with over 3,000 passengers reported a major outbreak around May 7. More than 100 passengers and crew were affected. Health officials confirmed the cause as norovirus.

According to Cruise operator Princess Cruises, enhanced cleaning protocols were introduced immediately after the outbreak was detected. Sick passengers and crew were isolated, and hygiene measures across dining and public areas were intensified.

What Is Norovirus?

Norovirus is a highly contagious virus that causes gastroenteritis, leading to inflammation of the stomach and intestines.

Speaking to HealthandMe, epidemiologist Dr. Amitav Banerjee, professor at DY Patil Vidyapeeth, Pune, described norovirus as “notorious because it spreads very fast.”

“It can spread through fomites like handles and knobs, and even a very low infectious dose—around 18 viral particles—can cause infection. So it spreads very fast,” he said.

He added that while many common disinfectants are ineffective against it, norovirus can be inactivated using bleach and chlorine-based cleaning agents.

Is The Norovirus Outbreak Of Concern?

Although outbreaks can look alarming, Dr. Banerjee emphasized that norovirus infections are generally self-limiting.

“In the ship, it can be managed with oral rehydration, and in severe cases, IV fluids can help prevent complications and mortality,” he said.

A recent report from the US also showed that norovirus can spread very rapidly from person to person on a cruise ship.

Dr. Banerjee also clarified that, unlike diseases with pandemic potential, norovirus outbreaks—while explosive in nature—do not typically pose a long-term global threat.

“So, this particular outbreak is not a cause for worry. It does not have pandemic potential, though it can spread very fast,” he added.

Read More: Hantavirus Alert on MV Hondius: One US Passenger Tests Positive, Two Others Show Symptoms

Who Is Most at Risk? What Are The Key Symptoms

Dr. Banerjee noted that extreme age groups, especially very young infants and the elderly, are at higher risk due to dehydration from diarrheal illness. However, deaths remain rare when proper care is provided.

Norovirus illnesses usually last between two and three days. Symptoms usually begin suddenly within 12 to 48 hours of exposure and may include:

• Nausea
• Vomiting
• Watery diarrhea
• Stomach cramps
• Low-grade fever
• Headache and body aches
• Fatigue

What You Can Do To Stop Its Spread

Because of how fast viruses spread, experts highly recommend preventive actions such as:

• Wash your hands frequently with soap and warm water, especially after using the toilet or before preparing food.
• Avoid visiting hospitals or care homes if experiencing symptoms.
• Stay home for at least 48 hours after symptoms subside to prevent spreading the virus.