Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

The Union Minister of Health and Family Welfare, JP Nadda, today launched two key national initiatives -- the Strategy for Artificial Intelligence in Healthcare for India (SAHI) and the Benchmarking Open Data Platform for Health AI (BODH) to boost the role of AI in the country's healthcare ecosystem.

The initiatives, launched at the India AI Summit at Bharat Mandapam, in the national capital, are aimed at promoting safe, transparent, and accountable AI in healthcare. It will also help strengthen the digital health ecosystem for equitable healthcare access.

What is SAHI and BODH?

SAHI is a national guidance framework to enable the safe, ethical, evidence-based, and inclusive adoption of AI across India’s healthcare system.

It aims to provide strategic direction on governance, data stewardship, validation, deployment, and monitoring of AI solutions, while supporting States and institutions in responsible adoption aligned with public health priorities.

"SAHI is not merely a technology strategy but a governance framework, policy compass, and national roadmap for the responsible use of AI in healthcare,” said Nadda.

He stated that SAHI will guide India in leveraging AI in a manner that is ethical, transparent, accountable, and people-centric. Nadda also emphasized that SAHI provides a structured framework for collaboration, ensuring that innovation flourishes while public interest remains paramount.

The second initiative, BODH, was developed by the Indian Institute of Technology Kanpur in collaboration with the National Health Authority. It is a privacy-preserving benchmarking platform that enables rigorous evaluation of AI models using diverse, real-world health data without sharing underlying datasets.

As a digital public good under the Ayushman Bharat Digital Mission, it is designed to strengthen trust, transparency, and quality assurance in Health AI deployment.

"The collaboration between Government and academia has led to the development of BODH -- the Benchmarking Open Data Platform for Health AI -- which provides a structured mechanism for testing and validating AI solutions before deployment at scale,” said Nadda.

Nadda reiterated that AI solutions must be rigorously evaluated for performance, reliability, and real-world readiness. Together, SAHI and BODH represent India’s commitment to building a trustworthy, inclusive, and globally competitive health AI ecosystem grounded in innovation, responsibility, and public trust.

AI An Indispensable Enabler to Viksit Bharat

Earlier, delivering the keynote address at a session themed “Innovation to Impact: AI as a Public Health Game-Changer”, at the Summit, Anupriya Patel, Union Minister of State for Health and Family Welfare, highlighted AI as an "All-Inclusive Intelligence".

She also emphasized AI's potential in addressing "health inequities across the country".

Patel called technology -- particularly AI "an indispensable enabler" in India's race towards the vision of a Viksit Bharat by 2047.

She highlighted the potential role of AI on India’s vast and diverse population, the rural–urban divide, and the dual burden of communicable and non-communicable diseases, which present unique challenges.

She also noted that AI has been integrated across the entire continuum of healthcare -- from disease surveillance and prevention to diagnosis and treatment.

While the national capital is seeing a significant rise in H3N2 Influenza A cases, experts explained that it's not just the common cold and people must not try to self-medicate.

Speaking to Health And Me, multiple experts stressed the need to treat the virus properly, as its symptoms can last longer and potentially lead to pneumonia.

What Is The H3N2 Virus?

H3N2 is a subtype of the Influenza A virus that causes seasonal flu. The symptoms are often stronger and more persistent, with many patients reporting prolonged fatigue, cough, breathing difficulty, and slower recovery.

It is highly contagious, spreading via respiratory droplets (coughing/sneezing) and contaminated surfaces. The symptoms usually last 5–7 days, with treatment focusing on rest and symptom management.

Dr. Mohit Saran, Consultant - Internal Medicine and Diabetologist, Manipal Hospital, Gurugram, told this publication: “H3N2 is not just a common cold. While symptoms may not appear instantly, they can lead to high fever, constant cough, body pain, and breathing issues. In some people, this can also increase the risk of pneumonia or the need for hospitalization if not managed early.”

The experts attributed the surge in the disease to factors such as changing weather, fluctuating temperatures and reduced immunity.

Who Is At The Highest Risk For H3N2?

Children, youngsters, senior citizens, pregnant women and people with low immunity or with conditions such as asthma, diabetes, or heart problems are more vulnerable to H3N2. Health care professionals and people who are exposed to crowded places may also be affected by this disease.

Dr. Atul Gogia, Head of Infectious Diseases, Sir Ganga Ram Hospital, told Health and Me that the H3N2 virus "predominantly affects elderly people and those who have comorbid illnesses".

"We need to be especially careful because this illness predominantly affects individuals with comorbid conditions, the elderly, and those who are more vulnerable to developing complications that may require hospitalization,” he said.

Why Does H3N2 Last Longer Than The Common Flu?

Symptoms of H3N2 infection can last for two to three weeks, with a lingering dry cough and fatigue being common.

The virus often affects the lower respiratory tract, leading to more intense coughing and breathing discomfort. Young children, older adults, and individuals with chronic health conditions are at higher risk of complications.

"H3N2 is considered more infectious because of its ability to mutate quickly and adapt to the human host. This high mutation rate allows the virus to evade the immune system more effectively and can lead to more severe outbreaks. It spreads easily through respiratory droplets, direct contact, and contaminated surfaces,” explained Dr. Manisha Arora, Director - Internal Medicine at the CK Birla Hospital(R), Delhi told HealthandMe

"Frequent changes in its surface proteins, a process known as antigenic drift, make it harder for the body to recognize and fight the virus, which can result in more hospitalizations and, in severe cases, increased mortality,”

How Can The Disease Be Prevented?

H3N2 can be prevented through regular handwashing, wearing masks in crowded places, avoiding close contact with people who are sick, and avoiding self-medicating. Flu vaccination, timely medical consultation for long-term fever, and adequate rest help reduce the risk and further spread of the condition.

The experts recommended that all adults above 18 consider annual flu vaccination ideally in August or September, unless they are currently experiencing flu-like symptoms.

Maintaining good hygiene, eating nutrient-rich foods, staying hydrated, and following healthy habits can help boost immunity.

Over 70 residents in Supertech Ecovillage-3, Royal Court Society and Himalaya Pride Society, Greater Noida have contracted food poisoning after they consumed a specific batch of buckwheat (kuttu) flour during Mahashivratri this weekend.

The widespread outbreak has caused panic and triggered a police investigation. As a result, officials sealed Prashant General Store, a retail shop in Royal Court Society and HD Spices, a primary warehouse in Chipiyana Buzurg village suspected of selling the spoiled batch.

Moreover, four people including the warehouse owner have now been detained by the Bisrakh police. Assistant Commissioner of Food, Noida, Sarvesh Kumar said lab tests are yet to confirm whether the infection was due to bacterial contamination, fungal toxins or adulteration.

This incident adds to a troubling trend of food and water contamination in the area, a topic that has recently reached discussions in Parliament. Improper storage allows toxic molds like aflatoxins to grow, triggering rapid-onset vomiting and dehydration, especially on the empty stomachs of fasters.

This "Buckwheat flour poisoning" occurs because the flour's high natural oil content makes it highly perishable; when stored in humid or warm conditions, these oils oxidize, creating a breeding ground for toxic molds and bacteria.

Why Is Buckwheat (Kuttu) Flour Harmful For Your Health?

Despite its reputation as a "pure" fasting food, buckwheat flour carries a hidden risk: its high natural oil content. Unlike refined grains, these healthy fats are highly unstable; when exposed to heat or moisture, they oxidize and turn rancid.

This transformation from a nutrient-dense staple to a source of food poisoning commonly occurs when households treat it like a non-perishable grocery item rather than the sensitive, short-lived ingredient it actually is.

The real danger of buckwheat flour lies in storage. Because buckwheat flour is used sporadically, it often sits in pantries in unsealed packets, warm cupboards or humid environments for months and becomes a silent breeding ground for dangerous molds and bacteria over time

The degradation is often hard to spot; a faint bitter aroma or slightly clumpy texture can easily be hidden by the strong spices and oils used in traditional fasting recipes.

Along with this, expired or damp buckwheat flour can harbor aflatoxins and other toxic compounds beneath the surface. Once ingested, these irritants attack the stomach lining, triggering a rapid physical "rejection," usually within just a few hours.

What Is Buckwheat-Caused Food Poisoning?

• Intense Nausea and Vomiting: Usually the first sign, as the body tries to expel the toxins.
• Acute Abdominal Pain: Sharp cramps or bloating in the stomach area.
• Fever and Chills: A sudden rise in body temperature as the immune system reacts.
• Diarrhea (Loose Motions): Frequent and watery stools.
• Extreme Weakness: Feeling dizzy, shaky, or completely drained of energy.
• Dehydration: Dry mouth and reduced urination due to fluid loss.

How To Safely Store Your Flour

• Buy Small, Buy Fresh: Purchase only the amount needed for the current fasting period. Avoid bulk buying buckwheat flour to store for the next season.
• Check the Date: Always look for the manufacturing date. If it’s more than two months old, it may already be turning rancid.
• Airtight & Cool: Transfer the flour to an airtight glass or metal container immediately. Store it in a cool, dry place, or better yet, refrigerate it to slow the oxidation of its natural oils.
• The "Sensory" Test: Before cooking, smell the flour. If it has a bitter, soapy, or musty aroma, throw it away. Fresh buckwheat flour should have a mild, nutty scent.
• Keep it Dry: Ensure your hands and measuring cups are completely dry before touching the flour, as moisture triggers fungal growth.
• Don't Mix Batches: Never mix new flour with old leftovers from a previous fast.

Who Is At The Highest Risk?

While anyone can get food poisoning, women, children and the elderly are at the highest risk. The practice of fasting can actually make the illness more dangerous. On an empty stomach, even a small amount of mold or bacteria can trigger an explosive physical response.

Furthermore, fasting usually involves lower water intake; once vomiting or diarrhea begins, the body loses its remaining fluid reserves instantly, leading to rapid, severe dehydration.