'We Have The Means To Prevent 80% Heart Attacks And Strokes', Expert Urges NHS To Give 'Polypill'

Updated Mar 6, 2025 | 05:00 AM IST

SummaryA polypill combining statins and blood pressure drugs could prevent 80% of heart attacks and strokes. Research shows it cuts cardiovascular risk by a third, benefiting millions globally with minimal side effects.
'We Have The Means To Prevent 80% Heart Attacks And Strokes', Expert Urges NHS To Give 'Polypill'

Image Credits: Canva

Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

End of Article

Virus Without Vaccine Hits California; No Need To Worry, Say Public Health Officials

Updated Mar 10, 2026 | 06:59 AM IST

SummaryHuman metapneumovirus (HMPV), a respiratory virus without a vaccine, is being detected in California wastewater and rising seasonally across the US. Doctors say it usually causes mild symptoms but can trigger pneumonia or bronchitis in vulnerable groups.
Virus Without Vaccine Hits California; No Need To Worry, Say Public Health Officials

Credits: Canva

Sick days are again piling up with a respiratory disease, not COVID-19 or the flu. This disease is most likely the one Americans have not heard of. This is HMPV or human metapneumovirus. Doctors have asked people to stay vigilant as seasonal flu virus could lead to pneumonia and bronchitis, and it is spreading in California wastewater and around the country. However, as per public health officials, there is nothing to get worried at this point.

As per the public database WasterwaterScan Dashboard, high levels of HMPV were detected across Northern California cities. The highest levels were reported in Redwood City, whereas elevated levels were found in San Francisco Bay Area and Napa's Wine Country. What's more dangerous is that this virus is without a vaccine.

The good news is that in other parts of country HMPV remains lower. However, the Centers for Disease Control and Prevention (CDC) noted that data from October 2025 shows the cases are trending up, especially during winter and spring.

Dr. Matthew Binnicker, director of the Clinical Virology Laboratory at Mayo Clinic, as reported by The Independent said, "In the late winter, early spring, it can account for five percent to 10 percent of all the respiratory infections that we diagnose in the United States. So it's definitely out there." Experts explain that other viruses like HMPV or influenza get a chance when COVID is quieter.

Read: HMPV Virus Cases Surging In California, New Jersey: Is It Dangerous?

Virus Without A Vaccine: What Is HMPV?

HMPV was first discovered in 2001 and is part of the Pneumoviridae family along with the Respiratory syncytial virus (RSV).

HMPV most likely spreads from an infected person to others through:

  • the air by coughing and sneezing
  • close personal contact, such as touching or shaking hands
  • touching objects or surfaces that have the viruses on them, then touching the mouth, nose, or eyes

In the US, HMPV circulates in predictable patterns each year, typically beginning in winter and lasting through spring.

The usually self-limiting and mild symptoms typically last 4 to 5 days. These include:

  • cough
  • fever
  • nasal congestion
  • shortness of breath

People at risk include:

  • elderly people
  • children
  • people with comorbidities

"The HMPV is not deadly, and there is no evidence of mortality or a severe transmission rate," former Indian Council of Medical Research (ICMR) scientist, Dr. Raman Gangakhedkar, told IANS, during the virus's outbreak in India in 2025.

“The virus may cause pneumonitis-like illness, but the mortality rates are almost unknown so far. HMPV has a global prevalence of about 4 per cent,” he added.

While no vaccine or treatment can prevent HMPV infection, to avoid the infection, individuals must:

Practice good hygiene and cover your mouth and nose with a tissue when coughing or sneezing, or use your elbow, not your hands, for it. And wash your hands properly, especially in healthcare settings.

Why Are People Hearing About The Virus Without Vaccine Now?

The reason people have not heard about it before is because its symptoms are nearly indistinguishable from other respiratory infections, so often it could go undiagnosed. Furthermore, earlier the COVID cases and influenza cases sparked up, which deviated the attention from HMPV. Now, with the season gone, and increased awareness around respiratory illnesses, greater attention to viruses like HMPV is also paid.

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1 In 7 Indians Affected By Mental Health Disorders; Govt To Launch NIMHANS-2 To Boost Care

Updated Mar 9, 2026 | 10:00 PM IST

SummaryExperts at the government-led Post-Budget Webinar series highlighted that several states continue to face a treatment gap ranging from 70 to 90 percent. Neurological and mental health conditions are also among the leading contributors to disability-adjusted life years in the country.
1 In 7 Indians Affected By Mental Health Disorders; Govt To Launch NIMHANS-2 To Boost Care

Credit: Canva

One in seven Indians, or over 14 percent of the population, suffers from some form of mental health disorder. Amid an increasing treatment gap -- up to 90 percent -- seen in several states, especially in North India, the government today reiterated the plan of launching a second National Institute of Mental Health and Neurosciences (NIMHANS) in the northern states.

NIMHANS-2 was first announced by Finance Minister Nirmala Sitharaman during the Union Budget 2026-27, to deliver specialized care for mental health and neurological disorders in north India.

Health experts and policymakers, as part of the government-led Post-Budget Webinar series, highlighted the growing burden of mental and neurological disorders in India and also stressed the urgent need to strengthen institutional capacity to meet emerging healthcare demands.

"One in seven Indians is affected by mental health disorders, while several states continue to face a treatment gap ranging from 70 to 90 percent," the experts said.

Noting that Non-Communicable Diseases (NCDs) account for over 60 percent of deaths in the country, they added that "neurological and mental health conditions are among the leading contributors to disability-adjusted life years (DALYs)," among the citizens.

Need For Tertiary Neuro-psychiatric Care

To address these, the experts called for ramping up tertiary mental health institutions and expanding specialized services.

The session, moderated by Vijay Nehra, Joint Secretary, Ministry of Health and Family Welfare, highlighted that North India currently lacks adequate tertiary neuro-psychiatric care facilities. These include areas such as:

  • advanced neuroimaging,
  • neurocritical care,
  • specialized neurological services

Further, making a virtual address at the Post-Budget Webinar, Union Health Minister JP Nadda also highlighted the government’s focus on strengthening mental healthcare services in the country.

"NIMHANS-2 will be established in North India to expand advanced clinical care, training, and research," Nadda said.

"In addition, the Central Institute of Psychiatry, Ranchi, and the Lokopriya Gopinath Bordoloi Regional Institute of Mental Health, Tezpur, will be upgraded as regional apex institutions to strengthen mental healthcare services in the eastern and north-eastern regions," he added.

Meanwhile, the experts also stressed the need to improve services in underserved and geographically remote regions, including the northeastern states, through better infrastructure, capacity building, and targeted deployment of trained mental health professionals.

They also discussed strategies for expanding advanced neuro-psychiatric care and reinforcing India’s overall mental healthcare ecosystem. They proposed:

  • Adopting a hub-and-spoke model supported by digital health platforms

This would allow tertiary institutions and centers of excellence to provide technical guidance, specialist consultations, and clinical support to district hospitals and community-level health facilities.

"Such a model would strengthen referral pathways and ensure that specialized mental health services are accessible to people even in remote and rural areas," the experts said.

  • Integrating services under Tele-MANAS

Both existing and upcoming campuses of NIMHANS must be integrated , as this will enable a robust nationwide tele-mental health network that ensures

  • timely counselling,
  • psychological support,
  • specialist consultations

  • Digital follow-up systems

The experts called for the seamless integration of healthcare facilities, aligned with the vision of the Ayushman Bharat Digital Mission and the ABHA ID ecosystem. This, they said, will

  • enable continuity of care,
  • Improve monitoring of patients,
  • Lead to better clinical outcomes

  • A national Brain-Mind Cloud Network

The Network proposed under the National Health Mission would connect premier institutions such as All India Institute of Medical Sciences (AIIMS), state medical colleges, and primary healthcare centers through a digitally integrated platform.

It could also facilitate

  • unified mental health records,
  • AI-based screening tools,
  • data-driven clinical decision support systems,
  • tele-neuro-psychiatric hubs at regional centers.

End of Article

HMPV Virus Cases Surging In California, New Jersey: Is It Dangerous?

Updated Mar 10, 2026 | 01:00 AM IST

SummaryAccording to the US Centers for Disease Control and Prevention (CDC), HMPV can cause upper and lower respiratory disease. There is currently no vaccine to prevent it, and no specific antiviral therapy to treat it.
HMPV Virus Cases Surging In California, New Jersey: Is It Dangerous?

Credit: Canva

California and New Jersey in the US are seeing an uptick in cases of human metapneumovirus (HMPV) -- a virus with no vaccine or treatment.

According to the US Centers for Disease Control and Prevention (CDC), HMPV can cause upper and lower respiratory disease. There is currently no vaccine to prevent it, and no specific antiviral therapy to treat it.

"Most people will recover on their own," the agency noted, but advised people who get sick to drink plenty of liquids, stay home, and rest.

As per the CDC's respiratory dashboard, the cases of HMPV steadily ticked up since November 2025. It accounted for over 5 percent of positive tests the week of February 14 through February 21.

While HMPV is not a "new" virus, having first been discovered in 2001, cases haven't spiked to this level in the US since an outbreak in April 2025, USA Today reported.

The New Jersey Respiratory Surveillance Report cited that about 4 percent of residents in the state are testing positive for HMPV. The HMPV cases, accompanied by RSV, COVID, and flu cases, are surging, increasing the number of people seeking emergency medical care.

As per the public database, WastewaterScan Dashboard, HMPV is rampant in Northern California -- specifically San Francisco, Marin, Vallejo, Napa, Novato, Santa Rosa, Sacramento, and Davis, the Independent UK reported.

What Is HMPV? Is It Dangerous?

HMPV was first discovered in 2001 and is part of the Pneumoviridae family along with the Respiratory syncytial virus (RSV).

HMPV most likely spreads from an infected person to others through:

  • the air by coughing and sneezing
  • close personal contact, such as touching or shaking hands
  • touching objects or surfaces that have the viruses on them, then touching the mouth, nose, or eyes

In the US, HMPV circulates in predictable patterns each year, typically beginning in winter and lasting through spring.

The usually self-limiting and mild symptoms typically last 4 to 5 days. These include:

  • cough,
  • fever,
  • nasal congestion,
  • shortness of breath

People at risk include:

  • elderly people,
  • children,
  • people with comorbidities

"The HMPV is not deadly, and there is no evidence of mortality or a severe transmission rate," former Indian Council of Medical Research (ICMR) scientist, Dr. Raman Gangakhedkar, told IANS, during the virus's outbreak in India in 2025.

“The virus may cause pneumonitis-like illness, but the mortality rates are almost unknown so far. HMPV has a global prevalence of about 4 per cent,” he added.

While no vaccine or treatment can prevent HMPV infection, to avoid the infection, individuals must:

Practice good hygiene and cover your mouth and nose with a tissue when coughing or sneezing, or use your elbow, not your hands, for it. And wash your hands properly, especially in healthcare settings.

End of Article