Image Credits: Canva
Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.
The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.
Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.
Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:
Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.
Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.
Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.
One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.
Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:
"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."
Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.
The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.
Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.
One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.
Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:
"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."
He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.
With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.
As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.
Credit: iStock
Planning an overseas holiday this summer? The UK government is urging British travellers to be aware of the dangers of methanol poisoning.
The warning comes after reports of British nationals becoming seriously ill or dying after unknowingly consuming alcohol tainted with methanol in popular tourist destinations.
The UK government has now added warnings about methanol poisoning to its travel advice for 29 destinations, including popular holiday hotspots such as Indonesia, Laos and Vietnam.
"We are working to raise awareness of the warning signs of methanol poisoning and urge anyone who suspects they may have been exposed to seek immediate medical attention, helping British nationals stay safe overseas," said Minister for Consular Hamish Falconer MP.
He urged travelers to check the latest travel advice before departure and act immediately if they suspect methanol poisoning.
Also read: Cyclospora Parasite: CDC, FDA Trace Outbreak In 5 States To Taco Bell Lettuce Supplier
As part of its 'Know the Signs' campaign, the Foreign, Commonwealth & Development Office (FCDO) has released new videos featuring the families and friends of British nationals who died after unknowingly drinking methanol-contaminated alcohol overseas.
The campaign includes first-hand testimonies from survivors and bereaved families to raise awareness of the warning signs and encourage travelers to seek urgent medical help if methanol poisoning is suspected.
"No one expects a holiday to end in tragedy, yet methanol poisoning can have devastating—and sometimes fatal—consequences. The courage of survivors and bereaved families in sharing their experiences will help raise awareness and could save lives," Falconer added.
Methanol is a highly toxic industrial alcohol that can sometimes be present in counterfeit, illegally produced or contaminated alcoholic drinks.
As little as 30 ml—about one shot—can be fatal for an adult, while even smaller amounts can cause permanent blindness, brain damage and other life-threatening complications.
One of the biggest dangers is that there is no reliable way to tell whether alcohol has been contaminated. Symptoms often do not appear until 12 to 24 hours after drinking, delaying life-saving treatment.
Read More: Botulism Cases Surge in UK: MHRA Issues Botox Safety Warning Over Rare Life-Threatening Side Effect
Early symptoms of methanol poisoning may resemble ordinary alcohol intoxication or a hangover, making it easy to miss.
Warning signs include:
Vision problems and breathlessness typically develop 12 to 48 hours after consuming contaminated alcohol.
Anyone experiencing these symptoms after drinking alcohol abroad should seek emergency medical attention immediately, as early treatment can be life-saving.
The UK government advises travellers to:
Credit: iStock
The US Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) have traced an ongoing Cyclospora outbreak in at least five states to shredded iceberg lettuce supplied to select Taco Bell restaurants.
The agencies have advised consumers: "Do not eat shredded iceberg lettuce from Taco Bell locations in Indiana, Kentucky, Michigan, Ohio, and West Virginia."
The FDA identified Taylor Farms as the supplier of the shredded iceberg lettuce served at the affected Taco Bell locations, where it is linked to illnesses in more than 1,644 people.
Taylor Farms is one of the world's largest producers of fresh salads and ready-to-eat foods, with production facilities across the US, Canada, Mexico, and Western Europe.
The FDA is working with the company to determine whether the contaminated lettuce was distributed to other businesses. Taco Bell has voluntarily removed the affected ingredients from the impacted restaurants.
The Cyclospora outbreak has been reported in more than 30 states. The CDC said this investigation is separate from other Cyclospora outbreaks currently being monitored nationwide.
Also read: H5N1 Bird Flu Reaches New Zealand; 12 Human Infections Reported Worldwide
Michigan has reported the highest number of cases, with state officials identifying leafy lettuce as the leading suspected source after interviewing more than 1,000 patients.
As of July 16, the state had reported more than 4,300 cases and at least 100 hospitalizations linked to the outbreak.
According to the CDC, 1,645 confirmed US cases have been reported since May 1, while more than 5,100 cases are under review to determine whether the infections were acquired domestically.
No deaths have been reported, although officials warned that confirmed case numbers could continue to increase through the end of August.
Earlier this week, Taco Bell said it has voluntarily and temporarily removed limited fresh ingredients from select restaurants as a precaution.
Notices posted at some Detroit-area Taco Bell restaurants last week informed customers that the chain was temporarily unable to serve lettuce, cilantro, onions, pico de gallo, and guacamole due to a nationwide recall, according to media reports.
The company said it will continue to monitor the situation and follow guidance from public health authorities.
"The health and safety of our guests is our top priority," Taco Bell said in a statement.
Health officials recommend:
Experts also recommend choosing whole heads of lettuce instead of bagged greens. Remove the outer leaves, wash the inner leaves thoroughly under running water, and cook produce whenever possible, as heat is the most effective way to kill Cyclospora.
Cyclospora cayetanensis is a microscopic parasite that causes cyclosporiasis, a foodborne intestinal illness. People become infected after consuming contaminated food or water.
Symptoms usually begin about one week after exposure, although they can appear anywhere from two days to more than two weeks later. Common symptoms include:
The CDC also advises people with persistent diarrheal illness to specifically request testing for Cyclospora, as routine stool tests do not always screen for the parasite.
Credit: iStock
The highly pathogenic avian influenza (H5N1) virus has been detected in New Zealand for the first time, raising concerns for the country's native birds.
NZ health authorities confirmed the virus in a wild seabird while stressing that there is currently no evidence of wider transmission within the country.
The infected bird, a brown skua, was found on Petone Beach in Wellington on July 10 and tested positive for H5N1. The detection comes just weeks after the virus was confirmed in Australia, a development that had prompted New Zealand authorities to prepare for its possible arrival. the country now confirming 14 infections.now confirming 14 infections.
New Zealand Biosecurity Minister Andrew Hoggard said the case appears to be isolated.
"There is no evidence of any mass mortality in wildlife or transmission between wild birds in New Zealand," Hoggard said, while urging the public to remain vigilant and report sick or dead birds.
Health and wildlife officials have launched enhanced surveillance to determine whether additional infections emerge in wild bird populations.
Also read: Australia’s H5N1 Detection Marks End Of Last Virus-Free Continent
The latest H5N1 detection comes as the US Centers for Disease Control and Prevention (CDC), in June, reported identifying 12 human H5N1 infections outside the US between August 4, 2025, and June 10, 2026.
According to the CDC, the cases were reported in:
Importantly, the CDC said no person-to-person transmission was identified in any of these cases. Most infections occurred after direct or close contact with infected poultry or other sick animals.
The agency said the international cases do not change its assessment that the risk of H5N1 to the general public remains low, but they reinforce the need for continued monitoring.
Cambodia's Ministry of Health on July 9 confirmed the fifth H5N1 human infection of 2026, in a 9-month-old girl from Phnom Penh. It is the 39th case in the country in the last three years.
The CDC noted that sporadic human infections are expected as H5N1 continues circulating widely among wild birds and poultry across multiple regions.
"While rare, these H5N1 bird flu cases in humans underscore the need for strong systems to monitor and prepare for influenza," the agency said, calling for robust surveillance and testing.
Read More: Cyclosporiasis Outbreak: US Probes Taco Bell Link; CDC Reviews Over 5,100 Cases
Scientists have identified five avian influenza virus subtypes capable of infecting humans:
Although the overall risk to the public remains low, health experts called for continued surveillance in birds, animals, and humans, which will be essential as H5N1 continues to spread geographically.
Health authorities recommend the following precautions:
© 2024 Bennett, Coleman & Company Limited