Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

From time and again experts have highlighted that flu has come early this year. In fact, they have predicted that this could be a 'nasty season', all thanks to the mutated version of H3N2 virus.

What Is The K Strain Flu?

Known as the superfly, this is H3N2 'subclade K'. It is a type of seasonal influenza A virus and people have not encountered much of it in the recent years. This is why there is less immunity against it. However, the National Health Service (NHS), UK, has already sent out a 'flu jab SOS' to vulnerable people.

NHS has confirmed that the super flu is circulating in England this year, and due to less immunity, it is making it easier to spread across people. The UK Health Security Agency (UKHSA) has urged people to get a flu jab. As per the early data, this year's vaccine has offered good protection despite the new strain.

Daniel Elkeles, chief executive of NHS Providers, said that the major concern is that H3N2 is associated with a more severe illness and superflu could be "a very nasty strain of flu". He said that UK could be experiencing a "tidal wave" of illness.

Read More: Unique Symptoms Of H3N2 Flu Strain In UK And How Long Infection Now Last

Who Needs The Flu Jab?

NHS offers free flu jabs to people who need it the most, which includes:

• anyone aged 65 or above
• those with long-term health conditions
• pregnant women
• care home residents
• carers for older or disabled people, or those who receive a carer's allowance
• people who live with someone who has a weakened immune system

NHS also includes frontline health and social care workers to get the jab.

The flu jab is also available in a nasal spray version, which could be administered to children aged 2 to 3 years as well as school-aged children, up to year 11.

Everyone else who is not in this list have to buy the jab.

Should You Buy The Flu Shot? How Long Does It Take For The Jab To Work?

Even if you are healthy, you should get the shot, say doctors. Vaccines are still working against the drifted influenza A (H3N2) subclade, also known as the super flu. The vaccines in high street chemists are sold for £20.

Anyone can be vaccinated, except for those who have a serious allergy to any of its ingredients or to the vaccine it self. The best way to know is to speak to the pharmacist and your GP.

For the vaccine to work, it usually takes up to 14 days. However, what is more important to not is that during the 14-day-long period, you are still vulnerable to catching the virus.

What Are Some Of The Misconceptions Around Flu Vaccine?

Some people think that it is the flu vaccine itself that has given them the flu, however, the truth is that while vaccine does not give you a flu, it gives your body the instruction it needs to fight off an infection, in case you catch it. While you may still catch the flu after being vaccinated, the affects will be milder and would not last as long.

The best part, the vaccine is frequently updated to match the strain or the version of flu that experts expect will be circulating.

Also Read: This ONE Key Symptom Will Help You Differentiate Flu From COVID, According To Doctor

What More Can Be Done To Protect Yourself Against The Super Flu?

Elkeles says that anyone experiencing flu or cold symptoms should wear a mask in public places. This is important for the "tidal wave" of illness in the UK. Speaking to Times Radio, he said, "When you were talking about anything like Covid, I think we need to get back into the habit that if you are coughing and sneezing, but you’re not unwell enough to not go to work, then you must wear a mask when you’re in public spaces, including on public transport, to stop the chances of you giving your virus to somebody else. And we were all very good about infection control during Covid. And we really, really need to get back to that now.”

Justin Timberlake had publicly revealed in his Instagram post about his diagnoses of Lyme disease, a tick borne illness that can cause lingering and unpredictable symptoms. The 44-year-old pop icon shared how this condition caused him "massive nerve pain", fatigue, and other symptoms as he went on his World Tour.

However, he did note that if diagnosed at an early stage, the condition is also treatable. It is spread by infected blacklegged ticks.

Justin Timberlake On Prioritizing His Health More After Being Diagnosed With Lyme Disease

In an Instagram post, he revealed that he had been battling with some health issues. In a report by PEOPLE, a source close to Jessica Biel said that the singer is prioritizing his health after the "grueling tour and Lyme disease diagnosis".

Justin Timberlake's Lyme Disease Diagnosis

Timberlake disclosed that during his Forget Tomorrow World Tour, which promoted his sixth solo album Everything I Thought It Was, he had been quietly “battling some health issues.”

“When I first got the diagnosis, I was shocked for sure,” Timberlake wrote. “But at least I could understand why I would be onstage and in a massive amount of nerve pain, or just feeling crazy fatigue or sickness.”

He admitted that the symptoms forced him to reconsider continuing the tour, saying, “I was faced with a personal decision. Stop touring? I decided the joy that performing brings me far outweighs the fleeting stress my body was feeling.”

Despite the physical toll, Timberlake pushed through his JT LIVE 25 tour leg, which included festival performances like Lollapalooza Brazil, before finally wrapping things up on July 31.

What Is Lyme Disease?

Lyme disease is caused by bacteria transmitted to humans through the bite of an infected black-legged tick. It's most common in certain parts of North America and Europe, especially during the warmer months.

The most common early sign of Lyme is a red rash that often resembles a bull’s-eye, typically appearing within 3 to 30 days after the bite.

The Center for Disease Control and Prevention (CDC), US, notes that the early symptoms can also mimic the flu, fever, chills, headache, fatigue, and muscle aches. If caught early and treated with antibiotics, most people recover completely within a few weeks.

However, for some, like Timberlake, symptoms can persist or worsen even after treatment. This condition, sometimes called Post-Treatment Lyme Disease Syndrome (PTLDS), includes ongoing fatigue, nerve pain, cognitive issues, and more.

“Lyme can be incredibly tricky because its symptoms overlap with many other conditions,” explained Dr. Christopher Bazzoli, an emergency medicine expert at the Cleveland Clinic, as reported by the New York Times. “When it’s not caught early, it can lead to a wide range of complications, from joint pain to neurological issues.”

In some untreated or severe cases, complications can include:

• Chronic fatigue
• Arthritis
• Heart palpitations
• Dizziness or shortness of breath
• Nerve pain
• Memory or concentration problems
• And in rare instances, meningitis

Doctors are still researching why some people recover quickly while others experience long-term effects. For now, treatment usually includes rest, medications for symptom relief, and in some cases, extended antibiotic therapy.

Timberlake has now joined a growing list of celebrities, including Avril Lavigne and Shania Twain, who’ve opened up about their experiences with Lyme disease in hopes of raising awareness.

Takeaway For You: If you’ve spent time in wooded or grassy areas and experience unusual fatigue, joint pain, or rashes, it’s worth getting checked for Lyme. Early diagnosis can make all the difference.

Scromting: the blend of two nightmares - screaming and vomiting. It sounds surreal, but it is as real as it could get. In an interview with the New York Post, Sydni Collins, 23, shared that she was "puking all morning." "I would let out yells or cries because nothing would come out. I was just dry heaving," she shares. This is how she ended up in the hospital with a feeding tube. What she was experiencing is called cannabis hyperemesis syndrome (CHS), a debilitating condition that triggers episodes of relentless nausea, abdominal pain, and severe vomiting in chronic weed users. She has been smoking weed daily as a teenager, since she was 16.

In the US, there are more than 2.5 million teens and 1 in 10 of them are casual cannabis users, with an additional of 600,000 teens considered to be addicted to it. Emergency rooms in the country have seen a steady rise in CHS cases over the last decade. In fact, the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) have also added CHS in its official diagnostic codes.

In Collins story, she became the trendsetter, because during her first hospital visit, she did not receive the diagnosis. However, her inability to eat a full meal afterward is what led to 7 ER visits in just one month. When she was finally admitted, she was only 87 pounds. She shared she would be in fetal position on the beds for hours, because that was the only way her stomach did not hurt. This is when she was finally diagnosed with 'superior mesenteric artery syndrome', which is a rare digestive disorder.

Misdiagnosis is common because there had been an absence of a diagnostic code for CHS.

What Are Experts Saying?

Dr David Streem, medical director of the Cleveland Clinic's Alcohol and Drug Recovery Center told USA TODAY that he has treated a range of patients with CHS over the years. He said that the condition is so severe that even the strongest anti-nausea medication that are given to chemotherapy patients, like Ondansetron, did not stop it.

However, there is a debate on CHS patients, and marijuana advocates like Paul Armentano, who is the deputy director of cannabis reform organization NORML, tells USA TODAY that CHS is actually "very rare" and that a lack of research on the syndrome has led to its misunderstanding. Armentano says, "The very fact that we're rebranding what was known for two decades as cannabinoid hyperemesis syndrome as scromiting. Scromiting is clearly sensational." It is made up, non-scientific, and sensational, says the cannabis advocate.

What is CHS or Cannabionoid Hyperemesis Syndrome, also known as the slang Scromting?

It is a side effect of prolonged use of marijuana. This results in nausea, vomiting, and abdominal pain.

As per Rome Foundation, a patients must meet the following criteria:

• Cyclical vomiting
• Presentation after prolonged marijuana use
• Relief of vomiting after the cessation of marijuana use

CHS was first reported in Australian medical literature in 2004. This is when a small study, published in BMJ analyzed 19 patients with cyclical vomiting after prolonged marijuana use.

While the research on what actually suddenly causes this syndrome is very limited, Armentano asks questions on if synthetic cannabis products, or a specific type of it leads to such a medical condition.

Stream said for treatment, IV drip of substance such as droperidol and haloperidol are often used in emergency rooms for CHS. Stream also said that Capsaicin, commonly referred to as hot pepper cream could also be rubbed on the abdomen for some temporary relief, along with hot showers or baths.