Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

Norwegian Cruise Line has notified passengers about two confirmed cases of Legionnaires’ disease linked to a December 2025 sailing aboard its ship, the Norwegian Encore.

In a letter dated February 12 and addressed to recent guests, the cruise operator said it is working with the Centers for Disease Control and Prevention (CDC) to investigate the illnesses. The two passengers were diagnosed after traveling on the vessel late last year.

What Is Legionnaires’ Disease?

Legionnaires’ disease is a serious type of pneumonia caused by Legionella bacteria. According to the cruise line’s letter, people become ill when they inhale tiny water droplets that contain the bacteria.

Unlike many respiratory infections, Legionnaires’ disease does not spread from person to person. Instead, the bacteria can grow in water systems and occasionally spread through mist or vapor from fixtures such as hot tubs, showers, whirlpool bathtubs, decorative fountains and misters.

The CDC notes that symptoms usually appear between two and 14 days after exposure, though in some cases they may take longer. The illness often resembles pneumonia and can include cough, fever, headache, muscle aches and shortness of breath. Some patients may also experience confusion, diarrhea or nausea.

While most people exposed to Legionella bacteria do not become sick, certain groups face a higher risk. Adults over 50, current or former smokers and individuals with underlying health conditions are considered more vulnerable to severe infection.

Investigation Underway, Tests So Far Negative

In its communication to passengers, Norwegian Cruise Line said it has launched onboard testing for Legionella bacteria. The testing includes water systems and fixtures such as hot tubs, showers and faucets.

“So far, all test results have been negative,” the company stated. It added that it remains unclear whether the two passengers were exposed through the ship’s water system or from another source unrelated to the cruise.

The cruise line urged anyone currently sailing or who recently disembarked from the Norwegian Encore to monitor their health. Guests who develop symptoms within 14 days of the end of their cruise have been advised to contact the ship’s medical staff and seek immediate medical attention.

CDC Monitoring the Situation

In a statement issued February 13, a spokesperson for the CDC confirmed to PEOPLE that the agency is aware of the cases associated with the Norwegian Cruise Line vessel and is supporting the investigation.

The development follows a separate CDC report released in October 2024 that examined 12 cases of Legionnaires’ disease identified among travelers on two cruise ships between November 2022 and June 2024. In that earlier investigation, private balcony hot tubs were identified as the likely source of exposure in two outbreaks.

The CDC noted that private hot tubs are often subject to less stringent operating requirements than public ones. The agency also warned that certain features — including outdoor placement, water retention between uses and systems involving recirculation, filtration or heating — can increase the risk of Legionella growth and transmission.

For now, health officials and the cruise line continue to investigate the source of the recent cases, as passengers are reminded to remain alert to symptoms and seek prompt care if they feel unwell.

Frida Baby thermometer is facing severe backlash after parents criticized the company's marketing language on its packaging. The parents claimed that the company cracked sexual jokes on using baby thermometers and that it crossed a line for a product that was designed for infants.

The controversy gained more traction this week after a social media user posted about it on X with photos stating that the marketing relies on sexual jokes.

An X user @staystaystace wrote: "sexual jokes to market baby products is actually sick and twisted @fridababy this is absolutely appalling and disgusting".

Frida Baby Thermometer: What Was The Problem With Marketing

The photos include a screenshot of the thermometer packaging on which the graphics are pointed out to be problematic and inappropriate by the parents. Furthermore, the caption on the official account of Frida Baby social media reads: 'This is the closest your husband's gonna get to a threesome...'

In another photo of Frida Baby 3-in-1 Eat, Forehead and Touchless Thermometer, the marketing phrase reads: 'How About A Quickie?'

Another photo on steps for using the humidifier, the caption on the packaging reads: 'I Get Turned On Easily'. While a fourth photo reads: 'I'm A [Powerful] Sucker'.

Parents claim that the brand has used sexual market phrases found similarly on self care toys and massagers for products which are made for infants.

Read: Six-year-old Child Dies Of Medical Negligence During MRI At Greater Noida Imaging Centre

Amid this, older content from 2020, including deleted social media posts resurfaced featuring a baby with visible nose discharge and the caption read: 'What Happens When You Pull Out Too Early #nosefrida #dontmove'.

More recently, Frida Baby again drew attention for an Instagram post that centered on breastfeeding. The carousel post includes slides with statements like: 'Boobs, everyone loves to see them', followed by commentary on how breasts are widely accepted in pop culture, but criticized in the context of feeding a child. The final slide reads: 'Show Us What Your Boobs Can Do', which directs readers to company's website. A user on the Instagram post commented: "Hey so why do you sexualize your products??"

Another photo that resurfaced from 2021 reads: 'Top Windi Pro-Tips to tap that [g]ass (and sometimes even [poop emoji]):

• - Massage it real good
• - Lube that ish up
• - Wear a poncho

However, there were some parents who also defended the brand's tone and argued that humor is clearly aimed at adults who are navigated through the realities of parenting.

Frida Baby Thermometer: How Did The Brand React?

In an emailed statement, as reported by Complex, the spokesperson for the brand said:

From the very beginning, Frida has used humor to talk about the real, raw, and messy parts of parenting that too often go unspoken. We do this because parenting can be isolating and overwhelming, and sometimes a moment of levity is what makes a hard experience feel human, shared, and survivable.

Our products are designed for babies, but our voice has always been written for the adults caring for them. Our intention has consistently been to make awkward and difficult experiences feel lighter, more honest, and less isolating for parents.

That said, humor is personal. What’s funny to one parent can feel like too much to another. We’re never trying to offend, push boundaries for shock value, or make anyone uncomfortable. Importantly, our tone is never separate from our product. The humor we use is always grounded in a specific feature, benefit, or innovation — a reflection of the real problem we are solving for families.

Frida was built to support families through some of the most vulnerable and transformative chapters of their lives. We stand firmly behind that mission. We will continue to show up with honesty, empathy, and courage.

With each decision we make, we will continue to evaluate how we express our voice so that our commitment to families is unmistakable and our tone always meets the moment.

A six-year-old boy died after his health worsened during an MRI scan at a private Greater Noida diagnostic centre. His family alleged medical negligence and claimed that he was administered a wrong or heavy dose injection.

As per the boy's father, Prashant Kasana, his son was taken to the centre for some test and was given an injection before the MRI procedure. The family said that during the MRI scan, the child was administered a heavy dose. Due to which his condition worsened and he also lost consciousness.

The family also said that when they asked for information about the child's condition and his medical report, they were not given any satisfactory answers. They also claimed that the doctors gave another dose to the child. The child's condition did not improve and the family had to rush the child to another nearby private hospitals. This is where the doctors declared him dead.

Six-year-old Child Dies of Medical Negligence: What Happened?

After this incident, family members accused the staff of the KB Healthcare Centre, where the child was first taken for an MRI scan. Villagers and workers of the Bharatiya Kisan Union also reached the spot and staged a protest.

The state spokesperson of the Bharatiya Kisan Union, Pawan Khatana, stated that the child was brought to the centre at 10.30am, and was in normal condition. As per the spokesperson, doctors did not disclose the quantity of the dose administered to the child.

As per Khatana, even after half an hour, the child did not gain consciousness and when the doctors checked him again, he was unresponsive and cold. The family took to another private hospital where he was declared dead. Khatana also alleged that there are many such unauthorized screening and imaging centres operating in Greater Noida and demanded a thorough probe.

Six-year-old Child Dies Of Medical Negligence: What Are The Authorities Saying?

Police on reaching the spot received the information, while protesters demanded for a fair investigation and strict action against those responsible. The Station House Officer of Neta 2 police station said the child was a resident of Reelkha in Dankaur. He was brought to a private pathology lab in Sector P3 for an MRI scan. As per the officer, the doctor administered the child with anesthesia for an MRI. After this, the child's health started to deteriorate.

Police has sent the body for post-mortem after completing the necessary legal formalities.

Six-year-old Child Dies of Medical Negligence: How Much Anesthesia Is Safe For A Child During MRI?

As per the National Institutes of Health (NIH), US and a study by the Yeungnam University Journal of Medicine (YUJM), drugs for deep sedation or general anesthesia for pediatric MRI are:

(I) Chloral hydrate: a sedative hyptonic agent with no analgesic properties

The study notes that the recommended dose of chloral hydrate is 50 to 100 mg/kg, or up to a maximum of 2g. The success rate of chloral hydrate sedation for pediatric MRI varies from 78% to 100%.

The United Kingdom (UK) National Institute for Clinical Excellence (NICE) also recommends the use of oral chloral hydrate with a wide margin of safety in children under 15 kg.

The study also notes that children "may be encouraged to take at least clear fluids 2 hours before the procedure for successful sedation without breaking institutional fasting protocols for chloral hydrate sedation".

(II) Pentobarbital: a medium duration barbiturate that provides potent sedation with no analgesic property.

As per the study, this can be administered via an oral or intravenous or IV route. The oral dose is administered between 4 to 8mg per kg and IV dose of 2 to 3 mg per kg.

(III) Midazolam: it is a short-acting water soluble benzodiazepine that has anxiolytic, sedative, amanestiec, and muscle relaxant properties.

It is administered through various routes, but IV is preferred. When administered through IV, it is given at the dose of 0.1mg per kg.

Anesthetic agents include propofol and sevoflurane.

Note: This article is not a substitute for medical consultation or prescription. The information is based on reports and research articles available online for public.