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Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.
The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.
Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.
Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:
Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.
Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.
Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.
One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.
Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:
"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."
Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.
The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.
Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.
One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.
Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:
"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."
He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.
With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.
As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.
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The “Make America Healthy Again” (MAHA) movement, led by Robert F. Kennedy Jr., played a key role in helping Donald Trump win the presidency in 2024. Two years later, it faces growing political opposition, with Democrats challenging the Trump administration’s healthcare policies and Kennedy’s approach to public health.
In a historic shift in the balance of power, the Democratic Party has won control of both the House of Representatives and the Senate in the 3 November 2026 midterm elections, delivering a major setback to Trump and the Republican Party. The results gives Democrats greater scope to scrutinise and reverse the administration’s healthcare agenda, including Medicaid funding, federal health agency budgets and vaccine policies.
However, their ability to reverse existing policies will be constrained by presidential veto powers and the 60 Senate votes generally needed to overcome a filibuster. The new Congress is expected to take office in January 2027.
More than 100 doctors, nurses and other healthcare professionals entered the 2026 US elections, in what was described as an unprecedented wave of candidates healthcare backgrounds.
Several Democratic candidates with healthcare and public health backgrounds secured major victories. These included:
Read More: US Midterms: Where Did Voters Support Abortion Rights And Where Did They Reject Them?
At the same time, several Republican candidates associated with healthcare and the MAHA movement also faced defeats. They included:
The MAHA movement, which promised to tackle chronic diseases and reform America's healthcare system, has faced criticism over Kennedy's approach to vaccines and public health. Changes to federal vaccine recommendations have become contentious amid a measles resurgence threatening the US' measles elimination status.
Pennsylvania reported 1,426 measles cases and five associated deaths as of October 30, 2026, its first measles fatalities in 35 years. The outbreak also triggered a public dispute between Kennedy and Governor Josh Shapiro over the deaths and claims about fetal tissue used in developing the MMR vaccine.
Beyond vaccines, MAHA's push to address ultra-processed foods, food additives and pesticides such as glyphosate has faced criticism over delays and concerns about corporate influence on food policy.
Autism has also emerged as a contentious issue. Trump's and Kennedy's September 2025 announcement on investigating possible autism causes, including a proposed link with acetaminophen use during pregnancy, and the CDC's July 2026 revision questioning the established scientific position on vaccines and autism drew criticism from health experts. Extensive evidence has found no causal link between vaccines and autism.
Looking ahead, Democratic lawmakers could use their control of Congress to scrutinise Kennedy's public health policies, demand scientific evidence behind federal health decisions and push for greater investment in vaccination and disease prevention programmes.
Trump's changes to childhood vaccination recommendations could become a focus of congressional scrutiny. In August 2026, he signed an executive order recommending separate MMR shots once individual vaccines become available and separate appointments for childhood vaccinations, where feasible.
Healthcare professionals have warned that additional injections and appointments could complicate vaccination for families and increase the risk of delayed or missed doses.
The administration has also moved away from the universal hepatitis B birth-dose recommendation. Under revised CDC guidance adopted in December 2025, parents of infants born to mothers who test negative can decide with healthcare providers whether to administer the vaccine at birth or begin the series later.
Democrats could hold hearings and investigate changes to CDC vaccine recommendations, the restructuring of its Advisory Committee on Immunization Practices (ACIP), and the removal of vaccine experts from advisory panels. They could also scrutinise staffing and funding changes at federal health agencies.
However, congressional oversight does not automatically allow Democrats to reverse executive decisions or remove Kennedy as HHS secretary. Their influence will depend on their ability to pass legislation, shape federal funding and secure support for changes to the administration's healthcare policies.
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One of the central healthcare issues surrounding the November 3 US midterm elections were abortion rights.
Voters in Virginia, Nevada and Missouri supported measures that protect access to abortion, while voters in Idaho voters rejected a proposal that could have formed new policies for reproductive healthcare freedom.
The results show how differently abortion access is being shaped across states after the US Supreme Court decided to overturn the constitutional right in 2022.
In 1973, the US Supreme Court recognised a constitutional right to abortion access in its landmark Roe v. Wade ruling. This meant states could not ban abortion before fetal viability, which is the point at which a foetus can survive outside the uterus.
That changed in June 2022, when the Supreme Court overturned Roe v. Wade through its ruling in Dobbs v. Jackson Women’s Health Organization.
The decision removed the federal constitutional protection and granted significant authority to regulate abortion rights to individual states.
Since then, US states have adopted different laws to control abortion rights. Some have introduced near-total bans, while others have added constitutional protections for abortion and enabled reproductive healthcare.
Virginia voters approved Question 1, a constitutional amendment protecting reproductive freedom, which includes access to abortion, contraception, prenatal care, childbirth, postpartum care, miscarriage management and fertility treatment.
The amendment also protects patients and healthcare professionals from punishment for their decisions related to reproductive healthcare.
It allows the state to regulate abortion during the third trimester, while granting exceptions when the pregnant person's health is at risk.
This has cemented Virginia's position as a pro-choice state, protecting reproductive healthcare access, particularly in the South, where several other states have imposed strict abortion regulations. The amendment is expected to take effect on January 1, 2027.
Also read: US Midterms 2026: 125 Doctors, Nurses And Health Experts Join Election Battle
Nevada voters approved Question 6, a measure that establishes constitutional right to abortion until fetal viability. After that point, abortion would remain permitted when necessary to protect the pregnant person's life or health.
The measure had also received voter approval in 2024. Nevada requires constitutional amendments to be approved in two successive elections before they can become part of the state constitution. The latest vote therefore clears the second hurdle.
Abortion was already legal in Nevada up to 24 weeks under a state law approved by voters in 1990. Question 6 provides an additional layer of protection by placing abortion rights in the state constitution, making them harder to change in the future.
Also read: US Midterm Elections 2026: Abortion, Medicaid, Measles And Healthcare Issues At Stake
Missouri voters rejected Amendment 3, which sought to repeal reproductive freedom protections approved by voters in 2024.
The proposed amendment would have significantly restricted abortion access, allowing it in very limited circumstances involving medical emergencies, fetal anomalies, and pregnancies resulting from rape or incest within the first 12 weeks.
With approximately 55% voting against the measure, the 2024 constitutional protections remain in place.
The result marks a second significant vote on abortion rights in Missouri in two years. In 2024, voters had approved the constitutional amendment that helped overturn the state's near-total abortion ban.
Idaho voters rejected Proposition 1, which would have established a statutory right to make reproductive healthcare decisions, including abortion until fetal viability.
The proposal also covered contraception, fertility treatment, pregnancy-related care, childbirth and miscarriage treatment. It sought to create exceptions to the state's near-total abortion ban.
According to reports 55.4% voted against the measure and 44.6% voted in favour after about 85% of votes had been counted. With the proposal defeated, Idaho's existing near-total abortion ban remains in place.
The results do not just affect if abortion is legally available in a state, they also shape how patients and doctors navigate pregnancy healthcare. Restrictions can create uncertainty for doctors, especially when a pregnancy threatens a patient's health but does not clearly meet the legal definition of an emergency. This can affect time-sensitive treatment decisions related miscarriage management.
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The climate crisis is also a major health crisis, but six proven measures could help prevent 1.6 million deaths every year, according to the World Health Organization (WHO).
A new WHO report, released ahead of COP31, highlights six climate and health interventions that could save lives while delivering trillions of dollars in economic and fiscal benefits.
“The climate crisis is a health crisis, but much of the harm it causes can be prevented with tools we already have,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General.
“This report shows that scaling up proven, affordable actions could save millions of lives, with the greatest gains in the countries that need them most. As governments prepare for the next round of climate negotiations, protecting health must be at the centre of climate action,” he added.
Also read: Big Lancet Report: Heat-Related Deaths Rise 36% Since Paris Climate Agreement, Global Warming Blamed
The report estimates that scaling up the six actions globally could prevent 1.6 million deaths annually, equivalent to one in every 40 deaths, based on modelled projections.
The six measures include:
Together, these actions could also help avoid 16.7 billion tonnes of CO₂ emissions, equivalent to 31% of global annual greenhouse gas emissions, excluding land use, land-use change and forestry.
Read More: Climate Change And Gut Health: How Heat, Drought And Unsafe Water Raise Risks, Global Experts Warn
Heat-health warning systems were the most cost-beneficial intervention assessed, generating an estimated US$835 in benefits for every US$1 invested. However, estimates varied across different scenarios and sensitivity analyses, ranging from US$364 to US$1,272 for every US$1 invested, the WHO said
Meanwhile, efficient fossil fuel pricing policies were estimated to deliver the largest overall economic welfare benefits, at US$3,041.10 billion. Estimates across different scenarios and sensitivity analyses ranged from US$690.59 billion to US$5,342.64 billion.
These policies were also projected to generate US$5,440.93 billion in fiscal benefits, with estimates ranging from US$3,442.96 billion to US$5,440.93 billion, the WHO said. The policies are also estimated to prevent 1.2 million deaths annually.
The 2026 United Nations Climate Change Conference, commonly known as COP31, will take place in Antalya, Türkiye, from November 9 to 20. The conference's dedicated COP31 Health Day will be held on November 9, the first day of the conference.
Governments are expected to share their climate reports and discuss ways to advance climate-resilient and environmentally sustainable health systems.
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