Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

A team of scientists at South Africa’s National Institute for Communicable Diseases has identified the strain of the Hantavirus that has caused three deaths and infected seven so far aboard the MV Hondius ship in the Atlantic Ocean.

In a presentation to the parliament today, the South African Health Minister revealed that the Andes strain of hantavirus, which spreads human-to-human, has been identified in two people who came off the cruise ship.

“Incredible work of @nicd_sa, South Africa, in sequencing the #hantavirus. There has been excellent collaboration as @WHO

works to coordinate efforts and actions of governments, experts around the world, the Ship to keep people safe,” said Dr. Maria Van Kerkhove, director of epidemic and pandemic preparedness and prevention at the World Health Organization (WHO), in a post on social media platform X.

The NICD scientists found that the Andes strain was the cause of infection in a Dutch woman who died in Johannesburg, and a British man who is still in hospital. Both had become ill on the ship, Reuters reported.

“This is the only strain that is known to cause human-to-human transmission, but such transmission is very rare and, as said earlier, only happens due to very close contact,” the Minister said.

Other strains of hantavirus are more commonly transmitted to humans through contact with infected rodents or their urine, droppings, or saliva.

Also read: Hantavirus Outbreak: WHO Flags 6 Suspected Cases; How The Rare Rodent-Borne Virus Spreads

What is Hantavirus? How Deadly Is The Andes Strain?

As per the WHO, hantaviruses are zoonotic viruses that naturally infect rodents and are occasionally transmitted to humans.

Globally, an estimated 100,000 to 200,000 hantavirus infections occur each year. The majority of these cases are in Asia, particularly China. Most are sporadic or occur in small clusters, linked to contact with infected rodents.

“Hantaviruses are a group of viruses carried by rodents that can cause severe disease in humans. Infection with hantaviruses is found in many parts of the world. Thousands of infections are estimated to occur each year," Van Kerkhove said.

The Ande virus is the only strain of virus with documented human-to-human transmission. It is more common in South America.

"Although uncommon, limited human‑to‑human transmission of HPS due to the Andes virus has been reported in community settings involving close and prolonged contact. Secondary infections among healthcare workers have been previously documented in healthcare facilities, though they remain rare,” WHO said in its situation report.

The WHO also currently assesses the risk to the global population from this event as low and will continue to monitor the epidemiological situation and update the risk assessment as more information becomes available.

"People really do need to understand that there are different degrees of person-to-person transmission," said Angela Rasmussen, a virologist with the University of Saskatchewan's Vaccine and Infectious Disease Organization, as quoted by CBS News.

Read More: Hantavirus on Cruise Ship: Symptoms, Risks, and Prevention

In the case of hantavirus, individual people are usually the end of the line, Rasmussen said, noting that this makes this cluster of cases unusual.

"So this virus — right now anyways — doesn't seem to be as big a risk as something like flu," the expert said.

While symptoms might not appear for weeks, the strain can escalate quickly, leading to severe respiratory failure with a death rate of roughly 40 per cent.

Long day at work? Let's order in. Not feeling happy? How about a cheat meal! And so on - nowadays, the concept of cooking for oneself seems to have become outdated. But little do we realise that these ordering-in habits can cost you a great deal later - it turns out these can speed up ageing. And it does not end here; eating takeaway food regularly can take away months of your life, and even undo all the health benefits of regular exercise. Researchers at the Peking University Third Hospital in China studied 43,000 adults in the UK to come to this conclusion.

How does eating takeaway food affect health?

Researchers conducted blood tests on people who regularly eat takeaway food. They found that their biological age was about three months ahead compared to people who ate home-cooked food. This means that their kidney, liver and immune systems were getting worse at a faster rate than usual. Researchers said that treating yourself to junk food every day could undo the benefits of regular workouts, too. Over the years, these effects could knock off months from your life.

The study, which was published in the BMC Medicine journal, also noted that the three-month difference in biological ageing, driven by dietary habits, might appear insignificant, but it translates to about a 2.2 to 2.7 per cent increase in early death risk. Over time, this can account for 16 per cent of the severe ageing caused by smoking. Some of the effects, as per experts, were linked to obesity and weight gain. However, people's health was worse even if they were not fat. Some of the effects were because of the weight gain and obesity link, but in the case of some participants, the effects were worse, even when they were not fat.

Why is takeaway food discouraged?

The study shows that takeaway food is harmful because of its high fat, salt, sugar and calorie content. But more importantly, it is about the absence of nutrients like fibre and protein. These foods are more likely to be eaten quickly and alone, without paying much attention to the poor quality of ingredients used. To make matters worse, plastic packaging contains harmful chemicals like PFAS - upon heating, these can release cancer-causing components. Researchers said that these factors could be associated with inflammation in blood vessels, a dip in levels of healthy gut bacteria, and a heightened risk of heart disease or type-2 diabetes.

Experts noted that the effects in terms of accelerated ageing and regular consumption of junk food can cancel the benefits of even regular workouts.

In yet another milestone in India’s digital healthcare, the government has launched the Swasth Bharat Portal, which aims to bring together the fragmented health systems in the country.

The portal, unveiled during the recent 10th National Summit on Innovation and Inclusivity by Union Minister for Health and Family Welfare JP Nadda, signifies a decisive shift towards a more integrated, efficient, and scalable digital public health architecture.

The portal aims to enable seamless integration with the Ayushman Bharat Digital Mission (ABDM) and support the exchange of patient records through the ABHA health account system.

What Is The Swasth Bharat Portal?

The Swasth Bharat Portal has been conceptualized as an aggregator platform that integrates existing program systems through an API-based federated architecture.

It enables interoperability and convergence, creating a unified digital layer across programs.

It is a one-stop integrated platform that brings multiple national health programs onto a single interface.

It eliminates the need for multiple logins and repetitive data entry, and significantly reduces the administrative burden on healthcare providers while enhancing efficiency at all levels.

The portal also provides a single platform for easy access, along with data visualisation tools and the use of data at the local level for monitoring and evidence-based planning.

It is ABDM-compliant and supports integration with ABHA (Ayushman Bharat Health Account), enabling seamless and secure exchange of patient health records.

It is designed to evolve into a comprehensive and interoperable digital health ecosystem, further integrating with national registries such as the Healthcare Professionals Registry (HPR) and Health Facility Registry (HFR).

Also read: India AI Summit: Union Health Minister Nadda Launches SAHI And BODH Initiatives To Boost AI In Healthcare

How Swasth Bharat Portal Will Boost Healthcare

The new portal will help:

• Reduce infrastructure duplication by 20–30 per cent: Independent hosting, storage, and compute resources are maintained across programs, which will be reduced when they are aggregated through Swasth Bharat

• Reduce Repetitive Data Entry: Similar beneficiary data that was entered across multiple systems will be entered on a single platform, thus reducing repetitive tasks by ~20–40 per cent.

• Unify HR Deployment: Separate development and maintenance teams are required in all programs; a unified system will reduce the HR burden and reduce duplication by ~20–40 per cent.

• Increase Interoperability: As the system is designed on a federated architecture via APIs, the interoperability will be higher.

Read More: Medical Miracle: World First Frozen Testicular Implant Gives ‘Infertile’ UK Man Hope of Fatherhood

The Swasth Bharat portal will also lead to substantial government savings both in terms of human resources, time, and IT infrastructure as compared to the current individual portals being managed by different program divisions, the Health Ministry said.

Further, the portal enables a shift towards an integrated, efficient, and scalable digital public infrastructure with significant efficiency gains.

The Swasth Bharat Portal thus represents a transformative step towards convergence, efficiency, and data-driven governance in India’s public health system.