Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.

The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.

Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.

Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:

Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.

Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.

Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.

Simplicity and Affordability of the Polypill Strategy

One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.

Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:

"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."

Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.

The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.

Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.

Is This a Case of Over-Medicalisation?

One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.

Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:

"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."

He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.

With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.

As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.

Barbie. A name too familiar for everyone growing up, now Mattel Studio has launched its first autistic Barbie. This is after Greta Gerwig's 2023 blockbuster movie that introduced the concept of diverse characters of Barbie, that Mattel launched its first Barbie with type 1 diabetes. The studio is definite about creating a diverse range of Barbie character, as an animated Barbie film too is in the development.

Why Is The Launch Of Autistic Barbie Important?

Autistic Barbie is the latest addition to Barbie's Fashionistas range, which is designed so more children can "see themselves in Barbie". The Barbie is created in collaboration with the US charity the Autistic Self Advocacy Network. The Barbie is designed to represent the ways autistic children may have experienced, including the way they communicate.

Barbie With Autism: What Are Her Features?

The Barbie's eyes gaze slightly to one side, which could represent how some autistic people avoid direct eye contact. The Barbie also comes with completely bendable elbows and wrists, which enables her repetitive physical movements such as stimming and hand-flapping that help people with autism to process sensory information, or even express excitement.

She also holds a pink fidget spinner on her finger, which helps her reduce her stress, wears noise-cancelling headphones, also in pink, to reduce sensory overload, and carries a pink tablet with symbol-based augmentative and alternative communication buttons on its screen that helps with her everyday communication.

Barbies earlier came in one-size-fit-all, often lacking the diversity and representation, this Barbie, however, wears a loose-fitting purple pinstripe A-line dress. This has minimized fabric to skin contact, and her shoes have flat soles that promotes stability and ease of movements.

Read: Hundreds Of US Children Have Type 1 Diabetes, Now Their Barbie Has It Too

Barbie's Representation Matters

The first Barbie came in 1959, and until 2019, there were no dolls with disabilities. Now, there are Barbies with diabetes, blind dolls, and Barbies with wheelchairs, Down syndrome, prosthetic limb, vitiligo, and hearing aids. There is also a Ken doll with a prosthetic leg, and another one who uses a wheelchair with a ramp, and one with hearing aids.

Jamie Cygielman, the global head of dolls at Mattel while announcing the autistic Barbie said, "Barbie has always strived to reflect the world kids see and the possibilities they imagine, and we’re proud to introduce our first autistic Barbie as part of that ongoing work. The doll helps to expand what inclusion looks like in the toy aisle and beyond because every child deserves to see themselves in Barbie."

She also added: “We engaged with the autistic community throughout the design process, always mindful that autism is experienced differently by every individual and is not always visible. The elements of this doll reflect how some people on the spectrum may experience and express the world, and we hope that by partnering with influential voices within the community, Barbie can continue to showcase a broader range of authentic experiences.”

What Is Autism?

As per the American Psychiatric Association, ASD is a complex developmental condition involving persistent challenges with social communication, restricted interests and repetitive behavior. While autism is considered a lifelong condition, the need for services and supports because of these challenges varies among individuals with autism.

As per the Centers for Disease Control and Prevention, an estimated one in 36 children have been identified with ASD.

The Department of Health (DOH) reported 411 measles infections in Philippines' Northern Mindanao in 2025, which was a 11% increase from 371 cases in 2024. Health officials are now warning people that the situation may get worse in 2026, as rate of unvaccinated children in the region also rise.

In 2025, 75% of the patients were unvaccinated.

In order to prevent outbreaks, DOH-Northern Mindanao and local health offices said that they will be deploying teams to administer Measles-Rubella (MR) vaccines to children and people aged six to 59.

“There are (measles) outbreaks in various parts of the country because of low (immunization) coverage and that includes our region,” said Germaine Labadan, head of the DOH-X Family Health Cluster.

In 2025, only 56.7% of Northern Mindanao's eligible population received MR shots, which led to a herd immunity well below the target of 95%.

Cagayan de Oro, a highly urbanized city, recorded the region’s highest measles-rubella (MR) coverage at 87.21%, while Bukidnon lagged at 49.71%. Coverage in other areas remained low, with Misamis Oriental at 51.87%, Misamis Occidental at 52.05%, Iligan at 52.55%, and Camiguin at 53.73%.

As part of this year’s Measles-Rubella Supplemental Immunization Activity (MR-SIA), children will be given booster MR vaccines along with Vitamin A supplements. The 21-day campaign will run from January 19 to February 13.

“This is open to all eligible, regardless of the immunization status of the child because the vaccine serves as a booster,” Labadan said. This also includes children who completed the first and second doses. “Parents may present the immunization booklet, but it is not necessary because all will be given a new one,” she said.

What Is Measles?

Measles, also known as rubeola, is a highly contagious viral illness that typically causes fever, cough, a runny nose, red and watery eyes, and a distinctive red, blotchy rash that usually begins on the face and spreads downward. The virus spreads through the air when an infected person coughs or sneezes and can lead to serious complications such as pneumonia or brain inflammation. Despite its severity, measles is preventable through a safe and effective vaccine, as per the Mayo Clinic.

How Contagious Is Measles?

Measles is among the most contagious diseases in the world. The virus spreads through airborne droplets that can linger in the air or on surfaces for hours. Up to 90% of unvaccinated people who are exposed to measles will become infected. A single infected person can pass the virus to an estimated 12 to 18 others through close contact or shared spaces. People can transmit the virus days before symptoms become obvious and continue spreading it after the rash appears, according to the World Health Organization.

How Long Is Someone Contagious With Measles?

Someone infected with measles can spread the virus from four days before the rash develops to four days after it appears. The virus spreads so efficiently that about 90% of people who are unvaccinated or have never had measles will become infected after being exposed.

In November, Canada lost its measles elimination status following a significant outbreak, according to the Pan American Health Organization, which works closely with the World Health Organization.

“It’s important to say that all the other 34 countries in the region, they keep their certification as measles-free,” said PAHO/WHO Director Dr. Jarbas Barbosa at the time, as per NPR News.

U.S. health officials have also warned that genetic links between outbreaks in different states suggest continued spread.

“The trajectory that we’re looking at now is that we do anticipate more cases well into January,” Bell said. “What that means for us nationally in terms of how they are defining our designation in this country as having eliminated measles is unclear.”

Nipah virus case detected in India's West Bengal, where two nurses are suspected of being infected by the virus. The case has come 24 kilometers away from West Bengal's capital, Kolkata, in North 24 Parganas' Barasat, where the patients are on a life support at a private hospital.

The blood samples collected from the nurses, one male and one female, were sent to the Virus Research and Diagnostic Laboratory, ICMR, at the All India Institute of Medical Sciences (AIIMS) in Kalyani, which is around 50 kilometers north of Kolkata in Nadia. Another report has been sent to Swasthya Bhawan, the state health department headquarters. The two nurses one from Nadia's Kalyani and another from East Burdwan's Katwa, work at the same hospital where the have been admitted.

Reports say that the nurses went home to Katwa around 10 days back, from where they may have caught the illness. The female nurse was initially admitted to a hospital in Katwa, later moved to Burdwan Medical College. Her condition kept worsening, this is when she was admitted in Barasat's private hospital, she is currently in the ICU. The male nurse is also on the ventilator support. Both patients are kept in isolation.

Update On The Nipah Virus Spread By West Bengal's Health Authorities

The sources from Swasthya Bhawan said that officials were handling the situation with extreme alarm as Nipah virus has a high rate of mortality and could spread rapidly. The Telegraph reported that top health officials form Union health ministry, including Union health secretary are in touch with Bengal chief secretary Nandini Chakravarty and state health secretary Narayan Swarup Nigam.

The health department has now begun contract tracing in Nadia, East Burdwan, and North 24 Parganas.

Chakravarty also asked people to not panic and remain alert, while avoiding to spread misinformation and follow hygiene practices. The State government has also launched three helpline numbers — 03323330180, 9874708858, 9836046212 — for public queries.

Union Health Minister JP Nadda also wrote to West Bengal's Chief Minister Mamata Banerjee, assuring full support from Centre. Banerjee too visited the hospital late on Sunday night.

What Is Nipah Virus?

As per the World Health Organization (WHO), Nipah virus infection is a zoonotic illness that is transmitted to people from animals, and can also be transmitted through contaminated food or directly from person to person.

In infected people, it causes a range of illnesses from asymptomatic (subclinical) infection to acute respiratory illness and fatal encephalitis. The virus can also cause severe disease in animals such as pigs, resulting in significant economic losses for farmers.

Although Nipah virus has caused only a few known outbreaks in Asia, it infects a wide range of animals and causes severe disease and death in people.

During the first recognized outbreak in Malaysia, which also affected Singapore, most human infections resulted from direct contact with sick pigs or their contaminated tissues. Transmission is thought to have occurred via unprotected exposure to secretions from the pigs, or unprotected contact with the tissue of a sick animal.

In subsequent outbreaks in Bangladesh and India, consumption of fruits or fruit products (such as raw date palm juice) contaminated with urine or saliva from infected fruit bats was the most likely source of infection.

Human-to-human transmission of Nipah virus has also been reported among family and care givers of infected patients.

Nipah Virus Symptoms

• Fever
• Headache
• Breathing difficulties
• Cough and sore throat
• Diarrhea
• Vomiting
• Muscle pain and severe weakness