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Heart attacks and strokes are among the leading causes of death globally, with millions suffering from cardiovascular diseases (CVD) every year. There are more than seven million people in the UK alone, with about 100,000 patients experiencing heart attacks annually. However, a group of researchers at University College London (UCL) estimate that one 'polypill' taken daily day could eliminate a majority of these cases dramatically lowering death tolls.
The proposed polypill, a combination of a statin and three blood pressure-lowering drugs, has been under study for over two decades. Experts argue that introducing this pill universally for individuals aged 50 and above could be more effective than the current NHS Health Check, which assesses risk factors every five years for those aged between 40 and 74.
Studies have repeatedly proven the effectiveness of the polypill in preventing CVD. A groundbreaking 2019 study in The Lancet found that five years' use of the polypill cut the risk of heart attack and stroke by a third. In addition, previous modelling analyses have estimated that if given universally to people over 55, the polypill might be able to prevent 80% of heart attacks and strokes.
Today, the NHS Health Check follows a risk-based model in which patients are tested for CVD risk factors and treated with drugs accordingly. Yet, as per UCL's study, this system has serious flaws:
Low Uptake: Just 40% of those eligible for the NHS Health Check choose to have it, leaving a considerable number of at-risk patients undiagnosed and untreated.
Ineffective Prediction of Risk: The majority of heart attacks and strokes happen to people at average risk levels, thus making it challenging to identify the need for intervention effectively.
Limited Effectiveness: Even at maximum take-up, the NHS Health Check programme is predicted to have fewer health impacts compared to a polypill initiative applied to the whole population.
One of the big benefits of the polypill is that it is so easy. In contrast to the existing screening-based model, the polypill scheme would not involve complicated medical tests or lengthy risk assessments. Instead, people reaching 50 would just have to fill out a few questions to determine possible side effects before they were prescribed.
Professor Aroon Hingorani of the UCL Institute of Cardiovascular Science, one of the strongest proponents of this scheme, says:
"Finally, the time is now to do much better on prevention. A population approach would prevent a lot more heart attacks and strokes than is done today with a strategy of trying to target a smaller group only."
Aside from the possible health implications, the polypill is also an economic solution. The drugs used are off-patent, thus cheap to produce and distribute. With the vast economic cost of managing CVD-related illnesses, a preventive model could result in substantial cost-saving for the NHS in the future.
The polypill has been proven to be effective by numerous international trials. In 2019, a randomised trial in rural Iran discovered that participants who took the polypill for five years had a 34% reduced risk of having a heart attack or stroke compared to non-participants.
Likewise, modelling research has indicated that even if only 8% of people aged over 50 took up the polypill regimen, it would still be more beneficial to their health than the NHS Health Check programme.
One of the main objections to the polypill strategy is the suggestion that it might result in the unnecessary medicalisation of a significant proportion of the population. But, it is argued, it should be considered as a preventative measure, not as mass medication.
Professor Sir Nicholas Wald of UCL's Institute of Health Informatics explains:
"Instead of being a 'medicalisation' of a significant proportion of the population, a polypill programme is a prevention measure to prevent an individual from becoming a patient."
He compares it with public health measures like water fluoridation or compulsory seatbelts—interventions that have been shown to have a significant impact in reducing public health danger at low individual cost.
With the evidence in favour of the polypill's effectiveness and viability overwhelming, experts are calling on the NHS to act now. It is their belief that substituting the NHS Health Check with a polypill-based prevention program could be the UK government's flagship policy under its pledge to put disease prevention ahead of cure.
As Professor Hingorani points out, "The status quo is not a justifiable option." With CVD still a major cause of death globally, taking a population-wide polypill approach could be a turning point for preventative medicine, potentially saving thousands of lives annually. The question now is whether the NHS will take up this call and establish a policy with the potential to transform the prevention of cardiovascular disease on a national level.
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Content creator and model Nara Smith recently revealed that her two-year-old daughter, Whimsy Lou, was diagnosed with cancer late last year. She shared the emotionally difficult journey her family faced over the past several months.
Nara is a South African-German model and influencer based in the United States. She is known for her short cooking videos in which she prepares meals from scratch, wearing extravagant and elegant outfits.
Smith said she and her husband, Lucky Blue Smith, took their daughter to the emergency room when they noticed “something suspicious” on her.
She said that although doctors were initially unsure of the cause, a visit to the pediatrician led to an urgent referral to a children's hospital. After undergoing X-rays, ultrasounds, and a biopsy, Whimsy was diagnosed with cancer. The influencer did not disclose the type of cancer her daughter has.
According to Smith, doctors informed the family that the cancer had already spread and that chemotherapy needed to begin immediately.
At the time, Nara was postpartum after welcoming her youngest child, Fawnie. She said that the diagnosis is one of the most challenging experiences her family has faced as she was caring for her other children and balancing work commitments.
She said spending time with other families in the hospital and connecting with parents through online communities helped ease the sense of isolation that often accompanies a childhood cancer diagnosis.
Although cancer is relatively rare in children, it remains one of the leading causes of disease-related deaths among children worldwide.
Unlike many adult cancers, childhood cancers are usually not linked to lifestyle factors. Instead, they often develop because of genetic changes in cells that occur early in life.
The most common cancers diagnosed in children include:
Early diagnosis can significantly improve treatment results, making it important for parents to seek medical evaluation as soon as possible.
Although childhood cancer is uncommon, it remains a major global health concern. According to the World Health Organization, an estimated 400,000 children and adolescents aged 0 to 19 years develop cancer every year, making it one of the leading causes of disease-related death among children and adolescents worldwide.
A large international study published in the Journal of the National Cancer Institute in 2025 analysed 16,821 childhood cancer cases from 47 population-based cancer registries across 23 countries.
For leukemia, the most common childhood cancer, three-year survival ranged from just over 30% in some regions to nearly 90% in others.
The study also supports the WHO Global Initiative for Childhood Cancer, which aims to increase the global survival rate for children with cancer to at least 60% by 2030.
Veteran actor Danny Glover recently shared that he has been living with Alzheimer’s disease for a few years now. The 79-year-old actor shared that he has been diagnosed for several years and is gradually adapting to the changes brought on by the progressive brain disorder.
In an interview on The Today Show, which aired recently, the Emmy-winning star explained that he was diagnosed after receiving an honorary Oscar in 2022. He also spoke about his experience of living with the disease.
Sharing that his movements, speech and memory have slowed, Danny Glover said, “I could live with it, in a sense. I’m sure as it advances, things are going to be different and changing. However, the support of his family, who he said, “have got my back”, was getting him through.
Glover also spoke about his diagnosis with People, in which he said he was still not able accept his new reality completely. He said that he was “still not accepting in my mind all parts of it”.
He said, “There are the moments that you keep remembering that validate the fact that you can remember stuff. And there are moments I’ll never forget.”
Even though Danny said that he has a hard time accepting the disease sometimes, he added, “I don’t feel like it’s the end of my life. There’s work to do. I still have my daughter, I have friends. I want to just say, your life continues.”
Also read: Doctors Day: From Burnout To Work Anxiety, The Mental Health Struggle Doctors Rarely Talk About
Here are the early symptoms of Alzheimer’s disease:
The symptoms often develop slowly and become more noticeable over the years. Common early signs include:
As the disease progresses, individuals may struggle to recognize loved ones, communicate effectively, and carry out daily activities independently.
There is currently no cure for Alzheimer's disease. However, several medications can help manage symptoms or slow the disease progression in some patients, particularly when treatment begins early.
Public figures like Danny Glover speaking openly about Alzheimer's can help reduce stigma that comes with the disease. It can encourage people experiencing memory problems to seek medical evaluation sooner. Early diagnosis can help patients and families seek treatment, plan for future care, and receive emotional and practical support.
Glover's announcement has once again brought global attention to a disease that affects millions of people worldwide and underscores the need for greater awareness and caregiver support.
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Illinois Governor JB Pritzker has once again claimed that US President Donald Trump is "suffering from dementia," an allegation the White House has strongly denied.
Speaking to CNN, Pritzker said Trump is "a different man" than he was a decade ago.
"Look, the man is continually suffering from dementia," Pritzker said. "I don't think he really understands what he's saying."
He added that Trump often makes statements without fully thinking them through.
"This is a man who has threatened to jail the mayor of Chicago, the governor of Illinois. He regularly threatens to go after people and, indeed, has used the Department of Justice to go after people," Pritzker said.
According to Pritzker, Trump has "concepts in his head" that he tends to blurt out without careful consideration.
He also urged people to compare Trump's public appearances from 2015 and 2016 with his recent speeches and press conferences.
"I really think that there's something genuinely wrong with him," Pritzker said.
However, Pritzker acknowledged that he is not medically qualified to diagnose the president.
'I'm Not a Doctor,' Pritzker, while criticizing what he described as Trump's increasingly disjointed speech patterns.
He said the way Trump "puts words and sentences together... they are almost divergent in the same sentences."
Read More: ‘Sea Or See?’ Donald Trump's Remark Sparks Fresh Cognitive Health Speculation
Trump, who became the oldest US president in history after turning 80 this year, has faced growing public scrutiny over his health.
Recent public appearances have prompted speculation after observers noted swollen ankles, bruising on his hands, verbal slips and occasional episodes in which he appeared drowsy during meetings and international summits.
Some physicians have also publicly expressed concerns about the president's physical and cognitive health, although none have diagnosed him with dementia.
Also read: Did Donald Trump Take Eli Lilly's Weight Loss Drug? What Did White House Say
A recently released book, Regime Change: Inside the Imperial Presidency of Donald Trump, claims the president's medical condition is among the administration's most closely guarded subjects.
Written by The New York Times White House correspondent Maggie Haberman and investigative reporter Jonathan Swan, the book is based on more than 1,000 interviews conducted over three years.
According to the authors, Trump now prefers shorter public appearances, seated events and staying close to the White House, unlike his extensive travel schedule during the 2024 presidential campaign.
The book also describes Trump as more of a "homebody" during his second term and claims staff members observed that he was sleeping less while spending early morning hours watching television, speaking on the phone and posting on Truth Social.
The White House dismissed the claims made in the book.
"President Trump's sharpness, unmatched energy, and historic accessibility stand in stark contrast to what we saw during the last administration when Democrats and the legacy media intentionally covered up Joe Biden's serious mental and physical decline from the American people," White House spokesperson Davis Ingle told the Daily Mail.
"President Trump is the sharpest and most accessible President in American history who is working nonstop to solve problems and deliver on his promises."
Meanwhile, Trump has also repeatedly rejected allegations of cognitive decline or other serious health issues.
His most recent annual physical examination concluded that he is "in excellent health."
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