For many months, the World Health Organization (WHO) has confirmed that the spread of the poliovirus remains a Public Health Emergency of International Concern. This concern was validated during the last few weeks of 2024, when vaccine-derived poliovirus type 2 (VDPV2) genetically linked to the Nigeria lineage was detected in wastewater samples in 16 cities in five European countries: Spain, Poland, Germany, the United Kingdom, and Finland. However, so far, no human polio cases have been reported in association with these detections. Concerns were raised in late 2024 when 94 confirmed polio-affected children were reported across 15 Nigerian states. No type-2 variant poliovirus cases have been confirmed in Nigeria so far in 2025. Understanding Vaccine-Derived PolioVaccine-derived poliovirus (VDPV) is a rare but concerning strain linked to the oral polio vaccine (OPV). Each drop of OPV contains a live but weakened version of the virus, designed to build immunity. However, occasionally, this weakened virus replicates in the intestines and is excreted in stool, spreading faster in areas with poor sanitation.As the virus circulates, it can mutate and revert to a form that causes paralysis, resembling wild poliovirus. If this mutated strain spreads among unvaccinated individuals, it can lead to an outbreak of circulating vaccine-derived poliovirus (cVDPV). The case in Meghalaya is currently being investigated to determine if it involves wild poliovirus or a vaccine-derived strain.Can Oral Vaccine Drops Trigger Polio Outbreak?The oral polio vaccine is effective in preventing the spread of polio and has played a crucial role in the near-global eradication of the disease. It contains attenuated (weakened) forms of one (monovalent OPV), two (bivalent OPV), or all three (trivalent OPV) types of the poliovirus. However, if the virus mutates, as mentioned earlier, it can trigger an outbreak of the deadly polio infection.The risk of vaccine-derived polio is exceptionally low compared to the benefits of widespread immunization. According to WHO, more than 10 billion doses of OPV have been administered to nearly three billion children since 2000, preventing countless cases of polio and saving millions of lives.ALSO READ: Once Suicidal, Counselor Sam Dylan Finch Gives 8 Solid Reasons To Live—Number 3 Is My FavoriteHow Lethal is Polio?Poliomyelitis (polio) is a highly infectious viral disease primarily affecting children under five years old. The virus spreads through person-to-person contact, mainly via the fecal-oral route, or through contaminated food and water. Once inside the body, the virus multiplies in the intestines and can invade the nervous system, leading to paralysis and death, in certain cases.While global vaccination efforts have nearly eradicated polio, isolated cases like the one suspected in Meghalaya highlight the importance of immunizing all populations against the deadly virus. The WHO continues to emphasize the need for vigilant surveillance and rapid response to any potential outbreaks, whether caused by wild or vaccine-derived poliovirus. ALSO READ: You Can't Say No To Sweets? Why You Always Have Room for Dessert