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Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
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Chewing tobacco contributed to an estimated 251,000 deaths globally in 2023, according to a new study from the Institute for Health Metrics and Evaluation (IHME).
The analysis, part of the Global Burden of Disease Study 2023 (GBD 2023) and published in The Lancet Global Health, found that more than 90% of the health burden was concentrated in 10 countries, with India accounting for the largest share.
"Chewing tobacco is not a uniform public health problem, and our findings show that a relatively small number of countries bear an overwhelming share of its health burden," said Gabriela Gil, lead author and research scientist at IHME.
Also read: Trying For A Baby? Tobacco Smoking Hurting Male And Female Fertility, Warns WHO
South Asia accounted for an estimated 210,000 chewing tobacco-related deaths, or about 84% of the global total.
Nearly 15% of people aged 15 and older in the region used chewing tobacco in 2023.
The highest age-standardized prevalence was reported in:
India recorded the highest number of chewing tobacco-related deaths among both males and females.
More than 90% of the male death and disability burden was concentrated in:
Among females, the countries were:
Read More: Trying to Quit Tobacco? Yoga Could Improve Your Chances, Suggests Study
Globally, use was higher among males than females and increased with age before peaking at 60–64 years.
In South Asia:
Bangladesh showed a different pattern, with female use higher than male use across age groups older than 30.
"These findings show why chewing tobacco control cannot take a one-size-fits-all approach," said Dr. Emmanuela Gakidou, senior author and professor in the Department of Health Metrics Sciences at IHME.
"Prevention and cessation strategies need to reflect how patterns of use differ by country, age and sex, as well as the cultural and social factors that shape tobacco use in each setting," Dr Gakidou added.
Researchers assessed chewing tobacco-related burden across six outcomes:
Stroke accounted for the largest share of health loss, at 55.9 disability-adjusted life-years (DALYs) per 100,000 people, followed by lip and oral cavity cancer at 17.4 DALYs per 100,000.
Chewing tobacco accounted for 17.3% of lip and oral cavity cancer DALYs globally, rising to 30.5% in South Asia.
Chewing tobacco-related DALYs increased 116% between 1990 and 2023, reaching 6.48 million. Of this:
The researchers noted that chewing tobacco has received less attention than smoked tobacco in global tobacco-control efforts.
They said stronger prevention and cessation measures, tailored to age, sex, country and local patterns of use, are needed to reduce the burden.
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Two Indian nationals have been held in the US over an alleged international scheme of smuggling and selling counterfeit Ozempic.
The US Food and Drug Administration (FDA) said Swapnadip Roy, 33, and Vicky Ramancha, 37, allegedly obtained counterfeit Ozempic from unauthorised sources in China and sold it to US distributors at deeply discounted prices between July 2023 and April 2024. Roy was extradited from Italy and has pleaded not guilty, while Ramancha remains at large.
This has raised fresh concerns about the risks of counterfeit GLP-1 medicines. The counterfeit products allegedly included fake packaging, package inserts, pen labels and needles, designed to make them appear like genuine Ozempic.
The alleged scheme continued even after the FDA seized some counterfeit products and issued a public warning in December 2023.
Counterfeit medicines may not contain the primary drug they claim to contain. The FDA warns that fake drugs can contain the wrong ingredients, too much or too little of the active ingredient, no active ingredient at all, or harmful substances.
With injectable medicines like Ozempic, contaminated or counterfeit needles can also create an infection risk.
This is particularly concerning with GLP-1 drugs because medicines like semaglutide and tirzepatide are increasingly being used for diabetes and weight management. A person buying a fake injection may therefore have no reliable way of knowing what they are actually putting into their body.
Acting FDA Commissioner Kyle Diamantas said, "Infiltrating the American drug supply with counterfeit products isn’t just a crime — it’s also a direct threat to public health and patient safety."
He added, "The FDA will continue to trace illicit networks wherever they lead, across borders and through complex supply chains, to ensure that anyone who seeks to profit off counterfeit medicines face accountability — all in our mission to keep Americans safe."
The Justice Department has stressed that the charges are allegations and that the defendants are presumed innocent unless proven guilty.
Assistant Attorney General A. Tysen Duva of the US Justice Department said, “These defendants allegedly exploited people’s health to pay themselves. We will keep pursuing anyone who seeks to deceive American consumers with counterfeit drugs.”
Also read: From 365 Shots To 52: How Could Lilly’s Newly-Approved Weekly Insulin Injection Change Diabetes Care
The FDA advises consumers to look for several warning signs.
Does the packaging look different from what you normally receive? Changes in fonts, spelling, labels, colours, printing quality or packaging can be warning signs of a counterfeit medicine.
The FDA specifically warns consumers to be cautious when buying GLP-1 medicines online. Unapproved or illegally marketed versions of semaglutide and tirzepatide may be counterfeit or contain harmful ingredients.
The agency recommends purchasing medicines only from state-licensed pharmacies.
A dramatically lower price can be a red flag, particularly when an expensive prescription medicine is being offered through an unauthorised seller. In the alleged US scheme, counterfeit Ozempic was sold to distributors at deeply discounted prices.
A new or unusual reaction after taking a medicine can also be a warning sign. The FDA lists unexpected side effects among possible indicators of counterfeit medicines.
Contact your doctor or pharmacist and verify the product before taking a dose if you suspect your medicine is fake. Patients should also avoid buying GLP-1 medicines through social-media sellers, unverified websites or other unauthorised sources.
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On Wednesday, Pennsylvania health officials reported its fifth measles-related death of 2026, as the state’s outbreak continues to expand in what can be described as the country’s most serious measles resurgence in decades.
The latest death involved Lancaster County resident who had tested positive for measles, according to the Pennsylvania Department of Health. The state now has 943 confirmed measles cases across 39 counties, with 40 new infections reported since September 28. At least 176 people have been hospitalised.
The latest death is the third reported in Lancaster County, which has remained one of the hardest-hit areas in Pennsylvania. This has raised the measles death toll in the state to 5, all of whom were unvaccinated.
Measles is one of the most contagious infectious diseases. It spreads when an infected person coughs or sneezes, with the virus capable of remaining in the air for up to two hours after the person has left an area.
The outbreak is particularly concerning because measles can cause serious complications, including pneumonia, dehydration, brain swelling and, in rare cases, death.
Pennsylvania’s news also comes as measles cases continue to increase across the country. The US has recorded 3,659 confirmed measles cases this year, according to CDC data cited by Reuters, making 2026 the country's worst measles outbreak in decades.
Also read: Pennsylvania Measles Cases Cross 900 As US Total Climbs To 3,659
According to the Pennsylvania health officials, all the five people who died due to measles were unvaccinated. Of the state's 943 confirmed cases, only four people were vaccinated.
Three of the deaths were among unvaccinated adults. The other two deaths were among infants who were too young to have received the measles, mumps, rubella (MMR) vaccine.
The numbers highlight the role of vaccination in preventing severe disease and controlling transmission. The MMR vaccine, which protects against measles, mumps and rubella, is highly effective. Two doses provide about 97% protection against measles.
According to Pennsylvania’s health department, less than 1% of measles cases occurred in people who were fully vaccinated against the virus. A total of 176 people have been hospitalized, while about 31% of cases occurred in people under 18.
In response to the outbreak, Pennsylvania administered more than 53,000 MMR doses in September, more than double the number typically given in a month.
There is also a dispute over how measles-related deaths should be counted. Pennsylvania has reported five “measles-associated” deaths, using a state definition that includes people with confirmed measles who die within 30 days of developing symptoms, unless another unrelated event caused the death.
The CDC, on the other hand, has confirmed two measles-related deaths nationally after changing its approach to rely on mortality data from the National Center for Health Statistics rather than state health department reports.
The disagreement has triggered a public dispute between Pennsylvania Governor Josh Shapiro and US Health Secretary Robert F Kennedy Jr. The CDC has said it is working with state epidemiologists to establish a more consistent definition for measles-related deaths.
Measles is preventable, but protection depends on maintaining high vaccination coverage across communities. When vaccination rates fall, the virus can spread rapidly, particularly among people who are too young to be vaccinated, have medical reasons or have not completed their recommended doses.
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