Ultra-Low-Dose CT Scans May Help Early Detection Of Pneumonia

Updated Mar 19, 2025 | 09:20 AM IST

SummaryCT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation.
Ultra-Low-Dose CT Scans May Detect Pneumonia in At-Risk Patients

Credit: Canva

Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.

"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.

Study Gives Solution To This

To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.

"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.

How Can You Detect Pneumonia?

Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:

Coughing with or without cough

Fever

Chills

Trouble breathing

Chest pain, especially when breathing deeply or coughing

Sweating or chills

Rapid heart rate

Loss of appetite

Bluish skin, lips, and nails

Confusion.

How to detect Pneumonia in coughing newborns and toddlers?

Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.

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Childhood Obesity Is A 'Do or Die' Crisis, Experts Warn At Times Network India Health Summit 2026

Updated Jun 20, 2026 | 07:58 PM IST

SummaryThe rising obesity levels in India are reaching a 'do or die' crisis level, and it is important to rein in the unhealthy eating habits for a healthy nation, warned experts at the ongoing Times Network India Health Summit 2026 today at Hyderabad.
Childhood Obesity Is A 'Do or Die' Crisis, Experts Warn At Times Network India Health Summit 2026

Credit: Times Network Health Summit 2026

The experts stressed the urgent need to tackle India's growing obesity crisis—particularly among children.

Speaking during a panel discussion on the future of women's and child healthcare, Dr. Sivaranjani Santosh, often referred to as the "ORS Lady of India," praised India's public health achievements, including the successful Pulse Polio Program, malaria control efforts, and improvements in child nutrition.

However, she cautioned that new challenges now threaten the country's health gains.

"There were many things we are lagging a bit also," Dr. Santosh said, stressing the need for fair food labelling, responsible marketing, and stricter regulation of irrational drug combinations.

She issued a stark warning about unhealthy eating habits, saying, "This junk food pandemic, this is where India needs to really, really focus on. Childhood obesity is a pandemic now. And it's like do or die right now for us."

Her comments highlighted growing concerns that poor nutrition and processed foods are driving obesity among children, increasing their risk of chronic illnesses later in life.

Also Read: Times Now Health Summit 2026: AI Cannot Replace Doctors, It Can Only Complement, Says Dr Santosh Sivaranjani

Echoing the concerns, Dr. T. Rajeshwari Reddy, Senior Consultant Obstetrician, Gynecologist, and Laparoscopic and Robotic Surgeon at Continental Hospital, explained that unhealthy lifestyles beginning in childhood are now contributing to a rise in hormonal disorders, infertility, and high-risk pregnancies.

"We are seeing a lot of people with hormonal imbalances and a lot of issues from teens, and that is what gets translated into infertility and high-risk pregnancy," she said.

Dr. Rajeshwari stressed that prevention must begin early. "The beginning has to be from birth only," she said, urging families to prioritize home-cooked meals, healthy routines, adequate sleep, and reduced screen time. She added that preventive healthcare should become the foundation of India's health strategy over the next decade.

Experts agreed that the future of Indian healthcare will depend on preventive medicine, technology, artificial intelligence, and stronger public-private partnerships to improve access to healthcare, particularly in rural areas.

They urged that India's fight against childhood obesity and lifestyle-related diseases must begin at home, with healthier food choices, greater awareness, and prevention from an early age.

Meanwhile, the AI in healthcare panel featured Prof. Renu John, IIT Hyderabad; Nishan Ali, Founder & CEO, Neurologic AI; Dr. Rahul Sawakhande, CEO, Aakaar Medical Technologies; and Dr. Rajah V. Koppala, Vascular & Interventional Radiologist and Founder, AVIS Vascular Center. The experts discussed how AI is driving predictive, data-led healthcare by improving diagnostics, telemedicine, and early disease detection while complementing doctors. They also stressed the need for better regulations, India-specific datasets, stronger data privacy, and greater collaboration between clinicians and engineers to expand quality healthcare across India.

The Times Now India Health Summit 2026 – South Edition commenced in Hyderabad, bringing together leading voices from government, medicine, research, and the healthcare industry to discuss the future of India's healthcare system. The summit featured renowned doctors, policymakers, hospital leaders, researchers, and healthcare innovators, with discussions spanning preventive healthcare, artificial intelligence, women's health, public health policy, and medical innovation.

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Ebola Outbreak Crosses 900 Cases, 200 Deaths In DRC, Uganda; WHO Says Outbreak Spreading Rapidly

Updated Jun 19, 2026 | 11:44 PM IST

Summary​Africa CDC epidemiologist Dr. Wessam Mankoula said the outbreak is approximately three times larger than any previous Ebola outbreak at a similar stage. Cases in Congo and Uganda have reached 915, while deaths has climb to 210.
Ebola Outbreak Crosses 900 Cases, 200 Deaths In DRC And Uganda

Credit: iStock

The Ebola outbreak caused by the Bundibugyo virus has reached 915 confirmed cases and 210 deaths in the Democratic Republic of the Congo (DRC) and Uganda, according to the Africa Centers for Disease Control and Prevention (Africa CDC).

The situation remains serious, with ongoing transmission reported in eastern DRC. Ituri Province continues to be the epicentre of the outbreak, accounting for the majority of confirmed cases in the country. The most affected health zones include Bunia, Mongbwalu, and Rwampara.

North Kivu has reported fewer cases than Ituri but has recorded a higher case-fatality rate, particularly in Katwa and Beni. Health officials say this underscores the need for early detection, safe referrals, quality clinical care, and strengthened infection prevention and control measures.

In Uganda, 19 confirmed cases and two deaths have been reported to date. No new cases have been recorded since June 5, 2026.

Community Mistrust Hindering Response Efforts

Africa CDC has identified several challenges hampering response efforts, including gaps in

  • contact tracing,
  • shortages of personal protective equipment (PPE)
  • essential medical supplies,
  • limited ambulance capacity,
  • community concerns surrounding isolation,
  • post-mortem testing,
  • household decontamination.

"Communities are central to stopping this outbreak. The response will only succeed if people trust the information they receive, know where to seek care, and feel that response teams are working with them," Africa CDC said in a statement.

Also read: US FDA Panel Recommends First-Ever mRNA Flu Shot For Older Adults: All About The Moderna Vaccine

WHO Warns Outbreak Is Spreading Rapidly

Meanwhile, the World Health Organization (WHO) had warned that the outbreak is spreading rapidly, even as response measures are being intensified.

"The outbreak remains serious and is evolving very fast. However, I have seen a response that is growing stronger every day," said Marie-Roseline Belizaire, WHO Regional Emergencies Director for Africa, speaking to reporters in Bunia, the epicentre of the outbreak.

The WHO estimates that at least 95 per cent of contacts must be traced to effectively contain the outbreak. As per Belizaire, contact tracing has improved to 75 per cent.

Read More: Natural Origin or Lab Leak? Gabbard Reignites COVID Origins Debate, Claims Fauci Funded Wuhan Lab Research

Ebola Outbreak 3 Times Larger

Africa CDC epidemiologist Dr. Wessam Mankoula said the outbreak is approximately three times larger than any previous Ebola outbreak at a similar stage, four weeks after a public health emergency declaration, AP News reported.

Although the outbreak was officially declared on May 15, health officials believe the virus had been circulating undetected for some time beforehand, contributing to its wider spread.

Another major concern is that the outbreak is being driven by the Bundibugyo strain of Ebola virus, for which there are currently no approved antiviral treatments.

Community mistrust of healthcare workers and public health officials, along with reliance on traditional beliefs and healers, is also complicating containment efforts.

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US FDA Panel Recommends First-Ever mRNA Flu Shot For Older Adults: All About The Moderna Vaccine

Updated Jun 19, 2026 | 05:22 PM IST

SummaryThe panel backed the vaccine, known as mFLUSIVA, for adults aged 50 years and older, concluding that its benefits outweigh its risks.
US FDA Panel Recommends First-Ever mRNA Flu Shot For Older Adults: All About The Moderna Vaccine

Credit: iStock

The US Food and Drug Administration's independent advisory panel has recommended approval of Moderna's mRNA-based influenza vaccine for older adults.

The panel backed the vaccine, known as mFLUSIVA, for adults aged 50 years and older, concluding that its benefits outweigh its risks.

If ultimately approved by the FDA, mFLUSIVA would become the world's first messenger RNA (mRNA) vaccine for seasonal influenza. The development could provide a new tool against a disease that causes an estimated 15 million to 60 million illnesses, 180,000 to 700,000 hospitalizations, and 17,000 to 75,000 deaths annually in the United States, according to data from the US Centers for Disease Control and Prevention (CDC).

What Did The FDA Advisory Panel Decide?

The recommendation came from the Vaccines and Related Biological Products Advisory Committee (VRBPAC), which reviews vaccine applications and advises the FDA.

The meeting marked the committee's first review of a new vaccine application since 2023 and could lead to the first vaccine approval under the second Trump administration.

In a unanimous vote, all nine panel members supported the use of Moderna's mFLUSIVA vaccine for adults aged 50 to 64 years, as well as for those aged 65 years and older—the age group that had previously raised regulatory concerns.

Also read: No Women Aged 20-24 Died of Cervical Cancer in England Over Five Years, Thanks to HPV Vaccine

However, before the vaccine can be made available for the upcoming flu season, it must receive formal FDA approval and be recommended by the CDC's Advisory Committee on Immunization Practices (ACIP). The CDC advisory panel has not recently convened due to ongoing legal and administrative challenges. An FDA decision on the vaccine is expected by August 5.

How Effective Is Moderna's mRNA Flu Vaccine?

According to Moderna, the vaccine outperformed standard-dose flu vaccines in adults aged 50 to 64 years.

In a large clinical trial involving approximately 40,000 adults aged 50 years and older, Moderna's mRNA vaccine reduced influenza cases by about 27% compared with another routinely used flu vaccine.

The company also conducted a smaller study among adults aged 65 years and older. The results showed that mFLUSIVA generated a strong immune response compared with a high-dose influenza vaccine already recommended for seniors.

FDA adviser Dr. Anna Durbin of Johns Hopkins University described the immune-response data as "very compelling," adding that "the vaccine looks very promising," AP News reported.

How Does The Vaccine Work?

Read More: Sickle Cell Disease: Why India Must Add Curative Treatment to Meet Its 2047 Elimination Goal

Like Moderna's COVID-19 vaccines, mFLUSIVA uses messenger RNA technology. Rather than introducing a weakened or inactivated virus, mRNA vaccines deliver genetic instructions that help the body's cells produce proteins that trigger an immune response. This approach allows vaccines to be updated more quickly and may improve protection against evolving viruses.

Is The Vaccine Safe?

Moderna's data showed no major safety concerns.

The most commonly reported side effects included:

  • Injection-site pain
  • Fever
  • Headache
  • Fatigue
  • Muscle aches

These reactions were generally temporary and are commonly seen with many vaccines. However, they occurred somewhat more frequently than with currently available flu vaccines. FDA reviewers noted that this is typical of mRNA-based vaccines.

What's Next?

If approved, Moderna plans to conduct a large post-approval study involving approximately 400,000 adults aged 65 years and older.

Half of the participants will receive the mRNA vaccine, while the other half will receive one of the currently recommended flu vaccines for seniors. The study is expected to continue across two influenza seasons.

A Moderna executive said the company hopes to make the vaccine available to patients in time for the upcoming flu season, Reuters reported.

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