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Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
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India has achieved a significant milestone in its organ donation movement, with more than 5 lakh people pledging to donate their organs, according to the Ministry of Health and Family Welfare.
The achievement reflects growing public awareness of organ donation as a life-saving act that can offer hope and a second chance to patients awaiting transplants. It also marks a major step forward in the government's efforts to promote voluntary organ and tissue donation across the country.
In a statement, the Health Ministry said the milestone demonstrates increasing public participation and trust in the organ donation ecosystem.
"The Government of India remains steadfast in its commitment to bridging the gap between the demand and availability of organs and tissues through sustained awareness generation, enhanced institutional capacities, and strengthened transplantation systems."
The ministry added that efforts continue to ensure organ transplantation practices remain ethical, equitable, transparent, and patient-centric.
Also read: US Hospital Performs World's First HIV-to-HIV Lung Transplant, Offering Fresh Hope for HIV Patients
The organ donation campaign has gained momentum in recent years, aided by repeated appeals from Prime Minister Narendra Modi during his monthly radio program, Mann Ki Baat.
In the 131st episode, the Prime Minister highlighted the growing awareness around organ donation and its impact on healthcare.
"Awareness about organ donation is steadily rising in India these days. This is helping those who are in need of it. It is also strengthening medical research in the country. Many organizations and individuals are doing extraordinary work in this direction," the Prime Minister said.
Read More: AI Cannot Replace Doctors, It Can Only Complement, Says Dr Santosh Sivaranjani
According to the latest government data, India has witnessed a fourfold increase in organ transplants over the last decade.
To make the process more accessible, the government launched an Aadhaar-based online organ donation pledge portal in 2023.
The platform, notto.abdm.gov.in, allows citizens to register their organ donation pledge securely and transparently.
Officials say the portal has significantly streamlined the registration process and encouraged greater public participation.
According to the All India Institute of Medical Science (AIIMS), you can choose to be a donor while you are alive, or your family can give their permission after you pass away.
The Organ Retrieval Banking Organization (ORBO) helps coordinate this entire process. If you want to donate your organs after you die, you can pledge to be a donor now.
Steps to pledge organ donation:
1. Fill Out the Donor Form
Credit: iStock/ UKHSA
The UK Health Security Agency (UKHSA) has issued a red heat-health alert across the Midlands and southern England until June 25, warning that extreme temperatures could pose a risk to everyone's health—not just vulnerable groups.
The alert, the highest level in the UK's heat warning system, comes as temperatures continue to rise and authorities warn of potential health emergencies, travel disruption and strain on critical infrastructure.
"Red heat health alert issued for East of England, East Midlands, London, South East, South West, and West Midlands. An amber heat health alert was issued for the North East, North West, and Yorkshire and The Humber," the agency said.
The UKHSA warned that many people struggle in hot weather and reminded the public that heat-related illnesses can become serious very quickly.
"Heat exhaustion and heatstroke are serious and potentially life-threatening conditions," the agency said in a post on X.
A red warning is the most severe level of heat alert issued by UK authorities. It indicates:
The warning is scheduled to remain in force from 09:00 BST on June 24 until 21:00 BST on June 25. The Met Office has advised people to avoid unnecessary travel where possible and follow guidance from emergency services and local authorities.
This is only the second time such a warning has been issued since the UK's extreme heat warning system was introduced in 2021. The first red heat warning was issued during the record-breaking heatwave of July 2022.
As temperatures climb, several schools across western England have announced early closures due to concerns about pupils and staff spending prolonged periods in overheated classrooms, the BBC reported.
Also read: WHO Sounds Alarm on Europe's Extreme Heat: Here's How Hot It Could Get Across Countries
The NHS says heat exhaustion usually improves if a person cools down within 30 minutes.
Common symptoms include:
Heatstroke is a medical emergency and requires immediate treatment.
Warning signs include:
Health officials recommend taking the following precautions during periods of extreme heat:
Older adults, young children, pregnant women and people with long-term conditions such as diabetes or heart disease are at greater risk of heat-related illness.
The NHS urged people to regularly check on family members, neighbors and friends who may need assistance during extreme temperatures.
Credit: iStock
In a landmark medical achievement, NYU Langone Health in the United States has successfully carried out the world's first lung transplant from an HIV-positive donor to an HIV-positive recipient.
Researchers described the procedure carried out on 56-year-old Bertrand Nelson, living with HIV for nearly 26 years, as a "watershed moment for the HIV-positive community". They noted that the medical feat could significantly expand the pool of organ donors available to people living with HIV.
"While these transplants are still only allowable under certain research protocols, this marks an expansion of options for people in need of a lifesaving organ," said Sapna Mehta, Clinical Director of the NYU Langone Transplant Institute.
Also read: HIV No Longer Barrier To Organ Transplants, Say Delhi Doctors After Successful Kidney Surgery
The transplant was performed under research protocols established through the 2013 HIV Organ Policy Equity (HOPE) Act, which allows organs from HIV-positive donors to be transplanted into HIV-positive recipients in approved research settings.
According to the researchers, while HIV-positive donor transplants involving hearts and abdominal organs have been performed previously, this was the first time such a procedure was successfully carried out for the lungs.
"Transplantation of hearts and abdominal organs has been done before, but this has not been done in lung transplantation," said Mark A. Sonnick, transplant pulmonologist at NYU Langone Transplant Institute.
Approximately 1.2 million people in the United States are living with HIV. Thanks to modern antiretroviral therapy (ART), most people with HIV can now live long, healthy lives, have near-normal life expectancy, and are unable to transmit the virus when treatment is effective.
Nelson was diagnosed with both HIV and sarcoidosis, an inflammatory disease that can affect multiple organs, particularly the lungs, in 2000. At the time, doctors said the condition was in remission.
However, in 2021, Nelson contracted Legionnaires' disease, a severe form of pneumonia that required weeks of hospitalization. The illness reactivated his sarcoidosis, which subsequently spread to his liver.
By 2024, his condition had deteriorated significantly. He required increasing amounts of oxygen to breathe and was referred to the NYU Langone Transplant Institute for evaluation for both lung and liver transplantation.
Following assessment under the HOPE Act research program, Nelson was approved for a dual-organ transplant.
On March 21, surgeons transplanted both a new set of lungs and a new liver during the same operation, making medical history.
Read More: Australia’s H5N1 Detection Marks End Of Last Virus-Free Continent
In a statement, NYU Langone said Nelson is doing well after the complex surgery.
"Nelson is now off oxygen for the first time in four years and getting back in shape after years of limited mobility," the statement read.
Nelson credited his mother, who will turn 82 in August, for her unwavering support throughout his health struggles.
"I want to be well for her," Nelson said. "I want her to see me thriving."
Nelson hopes his experience will encourage others and draw attention to the need for greater access to organ transplantation within the HIV community.
"There are so many others who need access to this level of care, and the more organs that become available, the better the odds of finding the right match and living a long life," he said.
As per the US National Institutes of Health, people with HIV can successfully donate or receive transplanted organs with reasonable success rates.
However, health care providers must consider and monitor potential drug interactions, kidney and liver function, and HIV viral suppression in people with HIV receiving a transplant. Further, the NIH advised HIV positive patients to continue taking all prescribed HIV medicines before and after transplant.
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