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Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
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A 40-year-old woman developed a rare and potentially life-threatening “flesh-eating” infection of the genital and perineal region about a week after shaving her bikini line and an application of herbal preparation.
The woman, a mother of four with a BMI of 39 kg/m², was diagnosed with Fournier gangrene, a severe form of necrotizing fasciitis that can rapidly destroy soft tissue around the genitals and perineum.
She spent 77 days in hospital undergoing treatment, wound care and reconstruction. Complete wound healing was documented by Day 121, reported doctors from King Saud University in Riyadh, Saudi Arabia, in the American Journal of Case Reports.
The woman presented with worsening pain and swelling of the left labia that had spread toward the area above the pubic bone. She also experienced vomiting and lower abdominal pain.
About a week before admission, she had undergone perineal shaving and had a herbal preparation applied to her vulva by an alternative practitioner. She had not used antibiotics or other topical treatments before seeking medical care.
On admission, her heart rate was elevated at 140 beats per minute, although she had no fever and her blood pressure remained normal. Examination showed marked tenderness and swelling, while laboratory tests indicated a significant inflammatory response.
Samples taken from the infected wound grew several different types of bacteria (E. coli, Klebsiella pneumoniae, and Enterobacter cloacae). However, no bacteria were detected in her bloodstream.
After doctors diagnosed her with Fournier gangrene, they performed urgent surgical debridement to remove the affected tissue.
She subsequently underwent multiple surgical re-explorations and negative-pressure wound therapy.
She was initially given broad-spectrum antibiotics, and later amoxicillin-clavulanate.
Fournier gangrene is a rare, rapidly progressive form of necrotizing fasciitis affecting the perineum and external genitalia. It is often described as a “flesh-eating” infection because bacteria can cause rapid destruction of skin and underlying soft tissue.
The condition is much more common in men, but women can also develop it. Reported male-to-female ratios range from 10:1 to 40:1.
Risk factors include diabetes, obesity, immunosuppression, malnutrition, peripheral vascular disease, kidney disease, malignancy and other serious underlying conditions. However, Fournier gangrene can also occur in people without the classic risk factors.
Local trauma, disruption of the skin barrier and invasive or cosmetic procedures can potentially provide an entry point for infection.
The researchers noted that Fournier gangrene may be underrecognized in women, partly because its symptoms can initially resemble a gynecological condition.
Early symptoms may include severe pain, swelling, redness and tenderness around the genital or perineal area. As the infection progresses, tissue destruction, skin discoloration, blisters or systemic signs of severe infection may develop.
"While men are more frequently affected, women should not be assumed to be at low risk. Severe or rapidly worsening pain and swelling around the genital or perineal region, particularly when accompanied by systemic symptoms, warrants urgent medical evaluation," the team said.
Treatment generally requires emergency surgical removal of dead and infected tissue along with broad-spectrum antibiotics and intensive supportive care. Survivors may require multiple operations, prolonged hospitalisation and complex wound management.
Fournier gangrene is a medical emergency. Although rare, it can progress rapidly and become fatal if treatment is delayed.
The condition has historically been associated with high mortality, with risk increasing when diagnosis and surgical treatment are delayed.
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US President Donald Trump recent move of overhauling childhood vaccine recommendations has sparked debates across the globe. Several US states have opposed to it too, refusing to follow Washington’s lead.
Trump signed the executive order on August 10, calling for federal childhood vaccine recommendations to be narrowed to vaccines routinely recommended for children against 11 diseases, down from 18 at the end of 2024.
It also calls for the measles, mumps and rubella (MMR) vaccine to be given as three separate shots and says childhood vaccines should, where feasible, be administered during separate medical visits.
The order also asks states to review their school vaccination requirements. But there is an important question here: states, not the federal government, generally set vaccine requirements for children attending schools.
At least 29 states and Washington, DC, had already rejected at least some federal vaccine guidance, choosing instead to rely on recommendations from medical organisations such as the American Academy of Pediatrics (AAP).
Among the states that have opposed Trump's order and maintained independent, medicine-based vaccine policies are Colorado, Maine and Washington.
Colorado has gone further by passing legislation allowing the state to rely on organisations including the AAP, American Academy of Family Physicians and American College of Obstetricians and Gynecologists when setting its childhood vaccine policy, rather than depending on federal CDC directive.
Maine has also said it will continue following guidance from established medical and public-health organisations instead of Trump's order.
Washington state officials said its school vaccine requirements have not changed for the upcoming academic year and remain based on recommendations from trusted medical and public-health experts.
This means Trump's order does not automatically change every child's vaccination schedule across the United States. The legal and political battle is likely to continue state by state.
Also read: What Trump’s Childhood Vaccine Order Means: When Will It Take Effect?
The MMR vaccine has been used as a combined vaccine for several decades. Trump’s order calls for separate measles, mumps and rubella vaccines, once they become available in the US.
Public-health experts have warned that separating vaccines could mean more appointments, higher costs and more chances for children to contract these infections as they may remain unvaccinated between doses.
The World Health Organization has also defended established immunisation schedules, saying they are based on decades of scientific evidence and proven clinical trials
The timing is particularly controversial as the US has already recorded 2,465 confirmed measles cases in 2026 as of August 6, according to the CDC.
Also read: Kennedy Announces Food Policy Reforms Under Trump’s MAHA Agenda: What Has Been Proposed?
The UK has taken a stand against Trump's newly proposed vaccine recommendation. On August 12, the UK's Medicines and Healthcare products Regulatory Agency (MHRA) reaffirmed that childhood vaccines are safe and effective and said there is no evidence that vaccines cause autism.
“The benefits of vaccination are endorsed by the NHS and all major UK public health and paediatric bodies,” said Dr Alison Cave, chief safety officer at the MHRA. She urged parents to follow NHS vaccination has an guidance.
The UK's routine schedule continues to use combination vaccines, including the six-in-one vaccine, and since January 2026 has included a universal two-dose chickenpox programme through the combined MMRV vaccine.
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The Supreme Court has asked 19 states and Union Territories that have not yet done so to consider declaring cancer a “notifiable disease”, stressing the need for a uniform system to report cancer cases across India.
The direction was issued on August 11 by a bench headed by Chief Justice of India Surya Kant, along with Justices Joymalya Bagchi and V Mohana, while hearing a Public Interest Litigation seeking mandatory cancer notification across the country.
The court was informed that 17 of India's 36 states and UTs have already notified cancer, following recommendations from a Parliamentary Standing Committee on Health and Family Welfare.
“Why don't you issue some mandatory guidelines for all States/UTs? There should be uniform policy,” CJI Surya Kant asked the Centre during the hearing.
The court subsequently asked the remaining states and UTs to consider the recommendations and take appropriate decisions, while also asking them to file compliance affidavits.
A notifiable disease is a condition that healthcare providers or designated authorities are legally required to report to the government when it is diagnosed.
Unlike infectious diseases, cancer is not being considered for notification because it spreads from person to person. The purpose behind SC's recommendation is surveillance.
Mandatory reporting to the government could give health authorities a clearer picture of how many new cancer cases are being diagnosed, where they are occurring, which cancer types are increasing and which populations may be disproportionately affected.
This information can help governments take initiatives towards planning screening programmes, cancer centres, diagnostic facilities, medicines, and other healthcare resources.
Despite the encouraging move, simply making cancer notifiable will not automatically lead to earlier diagnosis and better planning for resources to treat and manage the disease.
However, more complete data can help identify gaps in screening and follow-up care and allow health programmes to be targeted more effectively.
Also read: Why Non-Smokers Too Are At High Risk Of Lung Cancer
The issue has been linked to alarming gaps in India's cancer surveillance system. The Parliamentary Standing Committee had recommended that cancer be made a notifiable disease to improve the accuracy of cancer incidence and mortality data.
The Committee also noted that cancer deaths can sometimes be recorded under broader causes, making it difficult to establish the true burden of cancer in the country. It recommended stronger cancer registration and a digital system for real-time data collection to anaylse the actual number of cases and their severity.
The PIL was filed by Dr Anurag Srivastava, former Head of the Department of Surgical Disciplines at AIIMS, New Delhi.
His petition states that the absence of mandatory reporting has resulted in inaccurate data and inadequate surveillance. It also proposes a centralised, real-time digital registry for cancer, similar to the CoWIN platform used during the COVID-19 pandemic.
Also read: The Office Actress Lucy Davis Reveals Incurable Stage 4 Breast Cancer: 'It’s Too Late For Chemo'
The Centre has pointed out that health is a State subject. Additional Solicitor General Anil Kaushik told the court, “Moreover, 17 states have notified the disease.”
The court's latest direction therefore puts the focus on closing the gap between states that already have mandatory notification systems and those that do not.
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