Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.

"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.

Study Gives Solution To This

To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.

"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.

How Can You Detect Pneumonia?

Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:

Coughing with or without cough

Fever

Chills

Trouble breathing

Chest pain, especially when breathing deeply or coughing

Sweating or chills

Rapid heart rate

Loss of appetite

Bluish skin, lips, and nails

Confusion.

How to detect Pneumonia in coughing newborns and toddlers?

Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.

The H1N1 virus continues to surge in India’s national capital, Delhi, with vulnerable groups more likely to develop severe illness. While the infection is self-limiting in most cases, it is leading to increased hospitalizations, with some patients requiring ventilator support.

Delhi has reported 2,308 cases of swine flu, with the number described as around eight times higher than the average in previous years. However, no deaths have been reported so far.

The government has asked people to follow precautions similar to those followed during COVID, including the use of masks, and hand hygiene. However, it advised people not to panic but remain alert to symptoms.

To understand more about H1N1, HealthandMe interviewed Dr GC Khilnani, Chairman, PSRI Institute of Pulmonary, Critical Care & Sleep Medicine, PSRI Hospital, New Delhi, who explained the current surge, symptoms, warning signs, treatment and preventive measures.

Q. H1N1 cases are rising sharply in Delhi. What is driving this surge, and how concerning is it?

A. There has been a clear rise in H1N1 cases, which is concerning because influenza can occasionally cause severe pneumonia, ICU admissions, and deaths. The virus is also known to mutate, raising concerns about severe disease and wider outbreaks.

However, the current H1N1 virus is the same as in 2025. In healthy people, it usually causes a self-limiting illness lasting three to five days, with sore throat, fever, body aches, headache and sometimes mild chest pain.

Severe illness is more likely in vulnerable groups, including those aged 70–80 years or older, people with diabetes or chronic lung disease, and those who are immunocompromised due to long-term steroids, cancer treatment or other conditions.

We currently have patients on ventilators at PSRI Hospital because of H1N1, though thankfully there have been no deaths so far. The actual number of cases may also be higher than reported because not everyone gets tested.

Q. Is the H1N1 strain currently circulating in India different from previous years? How contagious is it?

A. It is a highly contagious strain. The ICMR has already said that it is the PDM09 Missouri type of virus, the same as it was in 2025. It has a very short incubation period of one to four days, and that means that it spreads very fast.

The attack rate is very high. That means that if it occurs in a family, all the family members are affected, and the contacts are affected. The spread is by droplet infection and also by touching non-living things like tables, chairs, or hands, as was happening in COVID. It spreads very fast. It's a short-term illness; therefore, the numbers are very high at this moment.

Q. What are the early symptoms of H1N1, and which warning signs mean a person needs hospital care?

A. Usual symptoms start with body aches, sore throat, headache, and fever, sometimes a very high-grade fever. Sometimes there is nausea and vomiting, and sometimes a little bit of chest pain is also there. It is sort of short-lived, and doesn't last for more than three to five days.

But if a person becomes breathless on mild exertion or at rest, or if the elderly person becomes drowsy or less responsive, then it's a point of worry.

If the oxygen level is below 91-92%, or the body turns blue, that means cyanosis (marked by a bluish or purplish tint to the skin or mucous membranes); these are signs of worry. Sometimes, if the chest pain is very severe, that should also not be ignored, and one should immediately go to the hospital.

Q. How can H1N1 progress from a routine flu infection to severe disease or complications?

A. It is a usual viral infection of the respiratory tract, upper as well as lower respiratory tract. It does cause a cytokine storm. It also causes multi-organ failure, and secondary infections are very common.

It is important for people who are susceptible and get admitted to hospital to look for secondary bacterial infection as well.

Q. Do antibiotics have any role in treating H1N1? How should it be treated?

A. There is absolutely, no role for antibiotics. We have the antiviral drugs, the most common being oseltamivir, popularly known as Tamiflu.

An important thing is that antivirals should be started within 48 hours of the start of the symptoms. After that, the role is very limited.

So, it is important that if the symptoms are there, it should be tested. The reports are available in 2–3 hours, and Tamiflu, is to be taken for five days, in a dose of 75 milligrams, that is, one tablet twice a day for five days.

The family members who are exposed, especially those who are susceptible, should also take a prophylactic dose of a 75-milligram tablet once a day for 7-10 days to prevent getting influenza illness.

Q. Does the seasonal flu vaccine protect against H1N1? Who should get vaccinated?

A. The flu vaccinations that are available in India definitely protects against H1N1. Like in COVID, it reduces the chances of infection, but more importantly, the severity of infection and mortality are reduced, underscoring the importance of vaccination.

Q. What is the best time to get the flu vaccine, especially now that cases are already rising?

A. One should take the flu vaccine once a year. The best months to receive this vaccination are before the expected outbreak.

Now that the outbreak is already underway, vaccination may offer limited immediate benefit, as it takes at least two weeks for the vaccine to become effective.

The best time to take it is, July-August because the outbreak usually comes in the monsoon period, or you can take it in January-February because the next outbreak occurs in March.

Q. What precautions should people take at home, workplaces and schools to prevent H1N1 transmission?

A. It is a question of—you know, during COVID, everybody was scared because mortality was highest. Everybody was following COVID-appropriate behavior.

Even now, people who develop symptoms should wear masks, even without testing, and avoid social events and crowded places to prevent spreading the infection to others.

The other thing which is more important is that those people who are likely to get severe disease—I have already described those people—should refrain from going to crowded places, like crowded markets or social gatherings and marriage parties.

Because, at this point in time it is likely that one person or another will be infected. Importantly, that person starts transmitting the virus one day before even getting the first symptom. So, you actually do not know who will be spreading it.

The infection rate is so high at this time that it is important for everybody not to go to crowded places if you are susceptible, meaning if you are 70-80 years old or your immunity is low.

And it is important that if you have to go to crowded places, then you should wear a mask and protect yourself.

Being rich is usually linked with better chances at living longer as one may have access to the best healthcare services, healthier food, free time for exercise and wellness and more. But a large international study has found a striking exception. It observed that the wealthiest individuals in America had survival rates comparable to some of the poorest people in Northern and Western Europe.

The study, published in the New England Journal of Medicine, analysed data from 73,838 adults aged 50 to 85 in the US and 16 European countries, following participants from 2010 to 2022. Researchers compared people according to their relative wealth within their own countries.

The findings suggest that wealth improves survival in both regions, but Americans had higher mortality at every wealth level than their European counterparts.

About 80% Of Wealthiest Americans Survived

The researchers found that about 80% of the wealthiest Americans were still alive at the end of the study period. That was roughly comparable to the survival rate among the poorest participants in Northern and Western Europe. Among the wealthiest Northern and Western Europeans, the survival rate was approximately 90%.

Lead author Irene Papanicolas, professor at Brown University School of Public Health, said, “We were surprised by that result.”

She said researchers might expect wealthy Americans to have access to high-quality healthcare, healthier food and safer environments, yet the data showed that their survival still lagged behind wealthy Europeans as well as the poorer populations .

Why Do Americans Have Higher Mortality Rate Than Europeans?

Also read: Bryan Johnson Reveals Meibomian Gland Dysfunction: What To Know About This Dry Eye Condition

The study does not find any one specific reason for the significant difference. However, researchers point to several possible contributors, including economic inequality, healthcare access, social safety nets, diet, smoking, _{physical activity}, stress and environmental risks. Differences in social and economic conditions could also affect health even among healthier people.

Papanicolas said the findings highlight factors that can affect health across different wealth levels, including “economic inequality or risk factors like stress, diet or environmental hazards.”

Co-author Sara Machado, a research scientist at Brown’s Center for Health System Sustainability, said where someone stands within their country’s wealth distribution matters for longevity, but so does how that country compares with others. She also noted that improving health outcomes is “not just a challenge for the most vulnerable”, as even people in the highest wealth group can be affected.

The US-Europe Life Expectancy Gap Has Widened

The findings come against a broader backdrop of declining US life expectancy compared with other wealthy nations. Researchers noted that the US and Western Europe had broadly similar life expectancy several decades ago, but the gap began widening around 1980 and kept going until it is now hard to ignore.

The study therefore raises a bigger question about whether individual wealth alone can protect people from broader health risks within a society.

The observational study cannot prove that living in the US itself causes higher mortality. The researchers identified possible explanations, but further research is needed to determine exactly why mortality remains higher among Americans across wealth groups.

Bruce Willis has been living with frontotemporal dementia (FTD) since 2023. While most dementia is not inherited, some rarer forms can have a stronger genetic link, according to the Alzheimer’s Society.

To gauge her risk of the neurological disease, which can affect behavior, communication, speech, as well as mobility, Bruce Willis's eldest daughter with Demi Moore opened up about undergoing genetic testing.

Rumer, the 38-year-old actress, told People that she underwent the APOE genetic test to understand her risk of developing dementia and learn about other health conditions she may be predisposed to, including Alzheimer’s disease and breast cancer.

“It’s terrifying to get answers sometimes,” she said, noting that there are genetic conditions in her family, including dementia and breast cancer.

However, she also believes that having information about her health risks can help her take proactive steps.

“I think when you have information, it’s power,” Rumer said.

Bruce Willis is continuing into his third year living with FTD. The degenerative condition often begins with language difficulties and eventually affects decision-making, emotional regulation, and behavior. His now wife Emma, is his primary caregiver.

Why Did Rumer Undergo Genetic Testing?

Also read: Bruce Willis Has Become More ‘Tender’ Amid Dementia Battle, Says Daughter

Rumer said knowing about potential health risks can help her take steps to improve her health, including working on inflammation and heart health.

She said being proactive about her brain health, gut health and reproductive health had been a priority even before her father’s diagnosis.

“I think health is one of those things that we take for granted until we don’t have it,” she said.

She said her efforts include taking supplements, no longer wearing perfumes, and cooking at home instead of worrying about microplastics from takeout containers.

Rumer said these steps are important not only for herself but also for her daughter and her ability to be around for her for as long as possible, the report said.

What Is An APOE Gene Test?

Cleveland Clinic defines an APOE gene test as a type of genetic test that identifies which variant of the apolipoprotein E (APOE) gene a person has.

Certain APOE variants are known to be associated with an increased risk of developing Alzheimer’s disease.

However, having an increased genetic risk does not mean a person will definitely develop the condition. Risk depends on multiple factors, with genetics being only one of them.

What Is The APOE Gene?

The APOE gene provides cells with instructions to make apolipoprotein E, a protein that combines with fats to form lipoprotein molecules. These molecules transport cholesterol and other fats through the bloodstream.

There are three main APOE alleles:

APOE-ε2 (APOE2)

APOE-ε3 (APOE3)

APOE-ε4 (APOE4)

Everyone inherits one copy of the APOE gene from each biological parent.

The combination of alleles can influence the risk of certain health conditions by affecting how the body transports cholesterol and other fats through the bloodstream.

Which APOE Variant Is Linked To Alzheimer’s Risk?

No gene has been found to directly cause Alzheimer’s disease. However, having at least one copy of the APOE-ε4 variant is associated with an increased risk of developing Alzheimer’s disease, Cleveland Clinic said.

Where Can APOE Testing Be Done?

Major pathology networks and specialized genomic laboratories offer medical-grade APOE genotyping using blood or saliva samples. There are also home saliva testing kits available.