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Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
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Irish health authorities are warning people against using retatrutide, an experimental weight-loss drug that has led to multiple cases of hospitalisation after people obtained it outside legitimate clinical trials through unlawful sources.
The warning comes as demand for the drug has grown online, particularly through fitness networks. Despite retatrutide not yet being approved, the masses have been reported to obtain and administer it without medical supervision.
Ireland's Health Service Executive (HSE) has reported patients presenting with serious side effects after taking the drug, including severe vomiting and kidney problems.
Prof Donal O'Shea, HSE Clinical Lead for Obesity, said doctors are seeing patients who have taken retatrutide obtained through unofficial channels.
He said, "Personal trainers who have been giving these jabs give no advice about side effects and how to manage those side effects, leading to real problems".
He also warned that some people are choosing not to disclose this information to the healthcare professionals, which has been making it harder to identify the cause of their symptoms and administer appropriate treatment.
He added, “They are too embarrassed to say they are taking it, leaving us blindfolded when we are trying to come to a conclusion.”
Also read: Eli Lilly’s Foundayo Launched In UK: Is the GLP-1 Pill Better Than Wegovy, Mounjaro?
Retatrutide is currently being developed by Eli Lilly as a once-weekly injection. Unlike existing GLP-1 medicines like semaglutide and tirzepatide, it simultaneously targets three hormone pathways --- GLP-1, GIP and glucagon. The combination is developed to target appetite, blood sugar regulation and energy metabolism simultaneuously.
Lilly's latest Phase 3 results have shown substantial weight loss. In one trial involving people with obesity or overweight and type 2 diabetes, participants receiving the highest studied dose lost an average of 20.8% of their body weight after 80 weeks.
Another Phase 3 trial reported average weight loss of up to 22.6% after 80 weeks in people with severe obesity and cardiovascular disease.
But promising results do not mean the medicine is ready for unrestricted use, especially before clearance. Its unapproved status indicates that researchers are still examining the drug for potential side-effects and other complications.
Lilly says retatrutide remains an investigational medicine and is legally available only to participants in its clinical trials. The company plans to submit it to the FDA in the first quarter of 2027.
Also read: Ideal Time to Undergo Fertility Treatment for Women Taking GLP-1 Weight-Loss Medications
The Irish warning is particularly concerning as people obtaining retatrutide outside clinical trials may not have an idea about what they are actually injecting, how concentrated the drug is or whether it has been manufactured and stored safely.
Prof O'Shea highlighted cases involving nausea, vomiting and kidney problems. He said, "We had somebody in at the weekend who was getting. Retatrutide twice a week in the gym they go to from their personal trainer and they were in hospital with vomiting and kidney disease. That’s going to happen widescale if people are taking this drug."
Severe vomiting can itself become dangerous because prolonged fluid loss can cause dehydration and acute kidney injury, particularly when someone is unable to keep fluids down.
Retatrutide's impressive weight-loss results have fuelled demand for it even though it has not been approved by the FDA. Recent reports spark concerns of a growing black market for the drug, with products being promoted through social media, online sellers, fitness communities and some unregulated clinics. Eli Lilly has taken legal action against companies accused of selling unauthorised retatrutide products.
This is particularly concerning because buyers may mistake a product marketed as “research use only” for a medicine that is safe for human injection. The HSE is urging people not to use retatrutide obtained outside a legitimate clinical trial.
Anyone experiencing severe vomiting, abdominal symptoms, weakness, reduced urination or other concerning symptoms after taking an unapproved weight-loss injection should seek medical attention and tell doctors exactly what they have taken.
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The Food Safety and Standards Authority of India (FSSAI) has flagged misleading claims by food business operators (FBOs) on products including coconut oil, energy drinks and baby food.
The claims include “100%” on coconut oil and “Energy Drink” on a caffeinated beverage, as well as claims around immunity, growth, digestion and nutrition in baby food. The regulator also flagged health and nutrient-comparison claims.
In a social media post, the Food Safety and Standards Authority of India (FSSAI) said that “major food business operators (FBOs) have taken prompt corrective action” following notices issued by the regulator.
The corrective measures include withdrawing misleading label claims and revising product packaging.
Mondelez India
Mondelez India Foods Pvt Ltd was flagged over misleading health and nutrient-comparative claims. It subsequently withdrew the claims and advertisements from e-commerce platforms.
Sapiens Labs
Sapiens Labs was flagged over a misleading claim and, after submitting its response, withdrew the claim and advertisements.
Vichi Agro
Vichi Agro Products Pvt Ltd, along with the concerned packer, was flagged over a misleading trade name and deleted the product from its platform.
Amway India
Amway India Enterprises Pvt Ltd, Delhi, was flagged over the use of “100%” in the name “100% Pure Coconut Oil”. The company said it had voluntarily removed the term from packaging and promotional material and discontinued old stock from sales channels.
Revised packaging without the claim has been finalized and is being rolled out progressively from September to October 2026.
Amway India was also flagged separately over the use of the term “Energy Drink” on a caffeinated beverage.
The company accepted the observation and removed the term from its product range, website and promotional material. Updated packaging is to be introduced from the production cycle beginning August 2026.
Juza Foods
Kerala-based Juza Foods was flagged over multiple claims for its baby food products. These included claims relating to nutrition, immunity, growth, digestion and nutrient content, besides comparisons with other milk powders.
The company acknowledged the violations and agreed to remove the misleading claims.
It also said its selling website had been shut and rectification completed, while steps were being taken for license-related changes and an e-commerce license.
Read More: After Diageo, FSSAI Inspects Pernod Ricard Plant, Tests Whisky Samples
The action is part of a wider drive in which FSSAI has issued more than 150 notices to food companies over misleading advertisements, false claims and labelling violations.
Nestlé India, PepsiCo, Coca-Cola India, Abbott India, Red Bull India, Danone India, Monster Energy India, Ferrero India and Kenvue are among the companies named by the regulator.
FSSAI has also widened enforcement to e-commerce platforms and food-service establishments, issuing 12 notices to e-commerce companies and more than 30 to food-service establishments, including major restaurant chains.
The regulator’s latest action underlines its focus on ensuring that food claims are substantiated and do not mislead consumers. The challenge, however, will be to ensure sustained compliance after companies withdraw or modify the claims.
Credit: AI Image
Particulate matter sized under 2.5 microns or 0.0025 millimeters (PM2.5) accounted for the largest share of air pollution-induced cancer cases worldwide, according to a new study.
The study, published in the journal Nature Health, showed that PM2.5 was attributable to 8.82 million of the 109 million cancer cases identified between 2000 and 2020. PM2.5 exposure was the dominant contributor to cancers of the respiratory, reproductive and endocrine systems.
Ambient air pollution is known to pose a global threat to public health. Although the carcinogenic potential of fine particulate matter (PM2.5), ozone (O3) and nitrogen dioxide (NO2) is a growing concern, comprehensive global assessments of their cancer risks remain limited.
The study, led by researchers from the Chinese Academy of Sciences, China, evaluated the effects of long-term exposure to PM2.5, O3 and NO2 on cancer incidence and quantified their attributable burdens worldwide, encompassing 109 million cases from 952 locations between 2000 and 2020.
The results identified PM2.5 as the dominant contributor. The researchers found that globally, each 10 microgram per cubic meter increase in PM2.5, ozone and nitrogen dioxide levels was associated with an increased risk of cancer by 16 per cent, 4.23 per cent and 11.7 per cent, respectively.
Exposure to nitrogen dioxide was attributable to 6.67 million incident cases, while exposure to ozone was attributable to about 2.6 million incident cases during the study period. Women were found to be consistently more vulnerable to most malignancies.
The study also showed that PM2.5-related cancer-inducing gene mutations extend beyond the respiratory system, particularly to cancers of the thyroid, esophagus, colon and rectum, and breast.
Further, each 10 microgram per cubic meter increase in PM2.5 was associated with a 17.9 per cent higher risk of kidney cancer and a 21.1 per cent higher risk of bladder cancer.
Biologically, PM2.5 exerts broad cancer-related impacts, possibly due to its small size and its ability to drive multiple processes, including systemic oxidative stress, DNA damage and immune dysregulation, the researchers said.
The study uses high-quality, globally representative cancer datasets involving populations from low-, middle- and high-income countries and therefore ensures generalizability of the findings, the researchers said.
"These findings provide critical impetus for public health policy initiatives aimed at mitigating the global cancer burden,” said the researchers in the paper.
According to WHO data, almost all of the global population (99%) breathe air that exceeds WHO guideline limits and contains high levels of pollutants, with low- and middle-income countries suffering from the highest exposures.
In 2016, the International Agency for Research on Cancer (IARC) classified outdoor (ambient) air pollution as a Group 1 carcinogen, primarily linked to lung cancer.
As per an April 2026 study by The Union for International Cancer Control (UICC), the risks associated with air pollution are similar to those caused by smoking tobacco. Exposure to air pollution can lead to cancer, stroke, respiratory and cardiovascular diseases, and other health issues.
Beyond lung cancers, air pollution has been linked to breast, colorectal, liver, kidney, brain, cervical and ovarian cancers, as well as childhood leukaemia.
Studies also suggest that long-term exposure to high levels of PM2.5 may be associated with a 21% increase in the risk of dying from cancer, and new evidence suggests that the risk of dying from air pollution exposure is increased for lung, breast, liver, colorectal and kidney cancers.
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