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Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
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Cancer death rates among American men and women declined from 2019 to 2023, continuing a downward trend that has lasted more than 20 years, according to a new CDC report.
The 2026 Annual Report to the Nation on the Status of Cancer, published in the journal Cancer, found that the continued decline in cancer mortality was driven largely by sustained progress against lung cancer.
“Cancer incidence was stable among males but increased slowly among females. Cancer mortality continued to decline, largely because of sustained progress against lung cancer,” the report said.
The overall cancer death rate during 2019–2023 was 145.4 per 100,000. It was higher among males (171.5 per 100,000) than females (126.3 per 100,000)
Cancer death rates decreased among males and females of every race and ethnicity. From 2004 to 2023, the cancer death rate declined by:
Between 2019 and 2023, death rates among males decreased for 12 of the 18 most common cancers, remained stable for four and increased for two.
Among females, death rates decreased for 12 of the 19 most common cancers, remained stable for three and increased for four. The largest declines were seen in lung cancer and myeloma.
Lung cancer recorded the largest decline in cancer mortality between 2019 and 2023:
Lung cancer incidence also decreased between 2018 and 2022:
Researchers attributed the progress partly to:
Lung cancer remains the leading cause of cancer death among both men and women in the United States. It is also the second most commonly diagnosed cancer among men, after prostate cancer, and among women, after breast cancer.
While cancer mortality continued to decline, incidence trends were different.
Overall cancer incidence rates were 504.6 per 100,000 among males and 443.0 among females during 2018–2019 and 2021–2022. The year 2020 was excluded because of pandemic-related diagnostic delays.
Incidence rates:
Among males, stable overall incidence was driven by a decline in lung cancer, which offset an increase in prostate cancer.
Incidence decreased for cancers of the:
Rates increased for cancers of the oral cavity and pharynx and pancreas, while rates for seven of the 18 most common cancers remained stable.
Prostate cancer incidence increased while lung cancer incidence decreased among males across every race and ethnicity. Colorectal cancer incidence decreased among White males but remained stable among other males.
The report also examined trends in new U.S. cancer cases from 2003 to 2022. Overall cancer incidence rose slightly each year from 2018 to 2022, driven by increases in breast cancer among women and prostate cancer among men.
Breast and prostate cancer remained the most commonly diagnosed cancers among women and men, respectively.
Despite the increase in prostate cancer, the overall rate of new cancer cases among men remained stable.
The report also noted that continued progress in cancer prevention and control will depend on tobacco-free environments, preventive care, screening, timely diagnosis, state-of-the-art treatment and survivorship care.
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The World Health Organization (WHO) has updated its contraception guidance, recommending mifepristone as an additional emergency contraception option and providing new guidance on contraceptive pills and implants.
The recommendations aim to expand access and give people more flexibility in choosing and using contraception.
“Choice is a gender equality issue,” said Pascale Allotey, Director of WHO’s Department of Sexual, Reproductive, Maternal, Child and Adolescent Health and Ageing.
“Contraception isn't one-size-fits-all. Men and women both need a range of options that reflect what science and innovation can now offer, weighed against convenience, invasiveness, behavior, reliability and accessibility. Real choice means the confidence and control to choose a method, change it, or stop it.”
The guideline covers five areas: three contraceptive methods not previously included in WHO guidance and two changes to existing contraceptive practices.
These include:
WHO recommends a 10–50 mg single dose of mifepristone for emergency contraception, taken as soon as possible and within five days of unprotected sex. A 10–25 mg dose may be preferred where available.
The number of women of reproductive age using modern contraception rose 87% between 1990 and 2022, from 467 million to 874 million. Yet an estimated 164 million women who want to delay or avoid pregnancy are not using contraception and have an unmet need for family planning.
WHO says expanding access must go hand in hand with identifying methods that lack sufficient evidence for wider use.
Men currently have relatively few contraceptive methods under their control, mainly condoms, withdrawal and vasectomy. Still, around 30% of couples rely on a male method.
A new global study in Contraception found that more than 75% of couples surveyed would be willing to use a new male contraceptive, while more than 85% of women said they would trust their male partners to take responsibility for contraception.
The WHO also developed its first Target Product Profile for male contraceptive methods, outlining desired characteristics such as safety, effectiveness, acceptability and affordability.
Several hormonal and non-hormonal male contraceptives are in development, with some candidates in advanced clinical trials. New reversible male contraceptives could potentially reach the market within the next five to 10 years, according to WHO.
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The Democratic Republic of the Congo is actively expanding Ebola treatment capacity as the country battles its worst and fastest-growing Ebola outbreak. But a growing shortage of health workers is threatening the ability to run the new treatment centres and contain and manage transmission and infections.
According to the latest figures by Congolese authorities on September 23, the outbreak has across into seven provinces, with 7,773 confirmed cases and 3,759 deaths. The WHO says transmission remains out of control, even though cases are going down in some areas.
The situation is particularly grim in North Kivu, where cases increased by 73% over three weeks. At the same time, cases fell by 26% in Ituri and 15% in Haut-Uele between August 31 and September 20, highlighting how differently the outbreak is behaving across provinces.
The country has rapidly increased its capacity to treat patients. By September 1, affected provinces had 59 facilities with 1,346 beds, compared with just one nine-bed treatment centre when the response began in May. More than 4,000 additional health workers had also been deployed.
But beds and buildings can only help if there are enough people to staff them. According to WHO officials, an Ebola treatment centre can require around 300 healthcare professionals, including doctors, nurses, anaesthetists and hygiene staff. Some newly established centres therefore do not have enough personnel to operate at full capacity.
This creates a difficult situation of treatment infrastructure being expanded, but the workforce needed to run it is not keeping pace.
Also read: DR Congo Begins Ebola Vaccinations Targeting 20,000 Health Workers As Fatalities Cross 3,500
Ebola treatment is particularly laborious as healthcare workers must provide intensive care while following strict infection-prevention measures.
Patients may require monitoring for dehydration, bleeding and other complications, while staff must work in protective equipment and follow procedures designed to prevent transmission.
The response has also been impacted by insecurity, population displacement, movement between communities and a strike by some health workers over unpaid wages. These factors can make it harder to maintain staffing.
Early treatment is key as many patients are still reaching healthcare facilities late. WHO previously reported that around 60% of weekly Ebola deaths were occurring in communities rather than treatment centres, pointing to delays in detection and access to care.
Also read: Ebola Transmission Falls In Some Areas Of Congo, But Outbreak Still Kills: WHO
Ebola can cause fever, weakness, vomiting, diarrhoea and, in severe cases, bleeding and organ failure. The longer a severely ill patient remains without appropriate supportive care, the harder the disease can be to manage. Treatment centres help isolate infectious patients helps break transmission chains.
Children are another major concern in the current outbreak. Nearly one in four confirmed cases are children, but they account for almost one in three deaths. Children under five have been particularly vulnerable as more than 60% of confirmed cases in this age group resulting in death, compared to fewer than 30% among adults, according to WHO.
The outbreak has been identified as being caused by Bundibugyo virus, one of the viruses in the Ebola family. WHO reported a case fatality ratio of 48.3% among confirmed cases in the DRC as of September 7.
There is currently no approved vaccine or specific treatment for Bundibugyo ebolavirus, which means, health officials are completely relying on breaking transmission chain and providing prompt medical care to control the spread.
But the latest unfortunate developments point to a problem that could make containment even more challenging. The response desperately needs enough trained people, supplies and access to affected communities.
As there is currently no vaccine for Bundibugyo virus, health authorities have approved 70,000 doses of Ervebo, vaccine meant for a much familiar Zaire strain of Ebola. Health workers in DRC have begun receiving the Ervebo doses as part of an experimental trial to test if it would work on current Ebola outbreak.
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