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Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
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A sexually transmitted form of Shigella, a highly contagious bacterium that causes severe diarrhea, is spreading rapidly among gay, bisexual and other men who have sex with men (GBMSM) in the UK, according to a new study published in The Lancet Infectious Diseases.
The study, led by researchers at the University of Cambridge, found that sexually transmitted Shigella strains are spreading faster than non-sexually transmitted strains and evolving resistance to key antibiotics at an alarming rate.
“Many men who have sex with men are unaware of the serious and increasing risk posed by sexually transmitted Shigella,” said Professor Kate Baker, senior author of the study from Cambridge’s Department of Genetics.
“Sexual infection is now a sustained part of Shigella transmission in the UK. It is vital that this message reaches the communities most affected, so we can help to prevent the spread,” Baker said.
“Sexually transmissible shigellosis needs to be treated as a distinct public health threat, requiring different surveillance, prevention, and treatment strategies.”
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Using genomic sequencing techniques similar to those used to track COVID-19 variants, researchers mapped how Shigella bacteria spread and evolved across the UK. The study, conducted in collaboration with the UK Health Security Agency (UKHSA), analyzed 3,514 laboratory-confirmed Shigella samples collected across the UK between 2004 and 2020 from people aged 16 years and older.
Sexually transmitted Shigella spread significantly faster than strains acquired through food, travel, or other non-sexual routes.
Over an evolutionary period of about 2.5 years, sexually transmitted strains spread an average of 117 km between related cases, compared with 46 km for non-sexually transmitted strains.
Sexually transmitted Shigella is primarily circulating within GBMSM sexual networks, particularly in major cities including London, Brighton and Manchester.
No statistically significant increase was seen among non-GBMSM populations, and little evidence was found that infections are spreading widely beyond these sexual networks.
More than half of all Shigella infections in the UK are now sexually transmitted.
Around 30% are linked to international travel, while the remaining cases result from localized outbreaks, particularly among young children, and household transmission.
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Professor Baker recommended the following steps to reduce the risk of sexually transmitted Shigella:
Researchers found that antibiotic-resistant sexually transmitted Shigella strains are spreading 71% faster than drug-susceptible strains. More than 70% of sexually transmitted Shigella strains were resistant to at least one clinically important antibiotic.
“This isn’t just one form of sexually transmissible diarrhea. This is multiple overlapping variants emerging that are all quickly becoming resistant to the drugs we use to treat them,” said Baker. “It’s highly likely that if you contracted your Shigella through sex you require different treatment to someone who contracted it through travel.”
Researchers also believe the rise in resistance may partly be driven by antibiotics prescribed to treat or prevent other sexually transmitted infections.
“Our evidence suggests that the variants of Shigella transmitting in sexual networks were actually getting resistant against treatments for other STIs, like gonorrhoea, so people need to remember that when they’re taking antibiotics they’re treating their whole body,” said Baker.
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As the world celebrates football through FIFA, new research is drawing attention to the long-term health risks faced by athletes in American professional football.
A new study found that former NFL players are nearly four times more likely to die from neurodegenerative diseases like dementia, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), than the general U.S. population.
A major new study has found that former National Football League (NFL) players are nearly four times more likely to die from neurodegenerative diseases like dementia, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) than the general population.
The research raised concerns about the long-term impact of repeated head injuries in professional football.
Published in eClinicalMedicine, the study analyzed mortality data from 19,824 NFL players who played at least one professional game between 1960 and 2019. The researchers from Mass General Brigham, Boston University, and the Concussion & CTE Foundation compared their health outcomes with those of the general U.S. population.
The co-senior author, Daniel Daneshvar, Harvard Medical School associate professor and chair of the Department of Physical Medicine and Rehabilitation at Spaulding Rehabilitation Hospital said, “This is the clearest population-level evidence we have ever had that NFL players are dying due to neurodegenerative disease at real and measurably higher rates.”
He added, “This study demonstrates that, when looking at athletes who have played in an NFL game, including nearly 20,000 players, across every official cause of death, the result is the same: NFL players are dying of dementia and Parkinson’s disease three to four times more often than they should.”
Despite having a lower overall risk of death than the average American, former NFL players experienced a dramatic increase in deaths linked to neurodegenerative diseases. Specifically, dementia-related deaths were 3.8 times higher, while deaths from Parkinson's disease were 3.88 times higher than expected.
Even after adjusting for other known risk factors, neurodegenerative mortality remained approximately three times higher than in the general population.
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Researchers found that the risk was particularly alarming among players who died before the age of 60. In this group, deaths from neurodegenerative diseases were more than 12 times higher than expected compared with the general population.
The study also identified a clear dose-response relationship between years spent in the NFL and disease risk. Players whose careers lasted five seasons or longer had nearly double the risk of neurodegenerative death compared with those who played between one and four seasons.
According to study co-senior author Dr. Jesse Mez of Boston University's CTE Center, the study supports evidence of long-term brain disease due to repeated head impacts.
"A fourfold increase in dementia rates from a presumed environmental cause is immense," Mez said, adding that previous brain bank studies suggest chronic traumatic encephalopathy (CTE) is most likely a major contributor.
Interestingly, the researchers found that NFL players actually had lower overall mortality, with reduced deaths from cancer, cardiovascular disease, and suicide compared with the general population.
The team proposed the Selection Through Athletic Resilience Survivor (STARS) effect. They suggest that individuals who reach the NFL often have exceptional physical fitness, resilience, healthier lifestyles, and better access to healthcare, all of which contribute to longer overall survival.
However, these advantages make the elevated rates of neurodegenerative disease even more striking. Researchers argue that because NFL players are generally healthier than average, the true effect of repetitive head impacts on brain disease could actually be underestimated.
The findings add to growing evidence linking repeated head trauma in contact sports to long-term neurological damage and are likely to intensify discussions around concussion prevention, player safety, and long-term monitoring of athletes.
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The Trump administration recently launched an initiative, encouraging hospitals across the United States to improve the quality of the meals they serve in terms of nutrition.
Launching the voluntary initiative aimed at making healthier meals more accessible to patients, visitors, and healthcare workers, the announcement was made by the U.S. Department of Health and Human Services (HHS).
The initiative, announced by the U.S. Department of Health and Human Services (HHS), is part of Trump administration's “Make Hospital Food Healthier” pledge.
Hospitals that participate commit to offering more nutritious food and beverage options, increasing transparency around nutritional information, and creating food environments that better support long-term health.
Health officials say hospitals should set an example by promoting healthy eating rather than offering meals and snacks that are high in sugar, sodium, and saturated fats.
HHS said while announcing the initiative, “Healthcare facilities should reflect the same evidence-based nutrition principles they encourage patients to follow after they leave the hospital.”
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Under the voluntary pledge, participating hospitals are encouraged to:
The administration says these changes will help create healthier food environments while supporting the prevention of chronic diseases like obesity, type 2 diabetes, and cardiovascular disease.
Millions of Americans eat meals in hospitals each year, whether as patients, family members, or healthcare workers. Public health experts have always argued that hospitals should encourage eating habits instead of relying heavily on processed foods and sugar-sweetened beverages.
Improving hospital food can also benefit healthcare staff, who often work long shifts and depend on hospital cafeterias and vending machines for meals.
The initiative supports the idea that nutrition plays a significant role in preventing and managing chronic illnesses, which remain one of the leading causes of death and healthcare spending in the United States.
The HHS pledge is voluntary, meaning hospitals are not required to participate. Instead, the department is encouraging health systems to adopt healthier food standards as part of their commitment to patient care and community health.
Officials say hospitals that join the pledge can help reinforce healthy lifestyle choices beyond clinical treatment by making nutritious foods more readily available throughout their facilities.
While the program does not mandate specific dietary standards, it represents another step in Trump administration's broader effort to promote healthier eating environments within healthcare settings.
As more hospitals sign on, health officials hope the initiative will have a positive impact on how healthcare institutions approach nutrition, turning hospitals into places that support healthy choices both inside and outside the examination room.
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