Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.

"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.

Study Gives Solution To This

To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.

"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.

How Can You Detect Pneumonia?

Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:

Coughing with or without cough

Fever

Chills

Trouble breathing

Chest pain, especially when breathing deeply or coughing

Sweating or chills

Rapid heart rate

Loss of appetite

Bluish skin, lips, and nails

Confusion.

How to detect Pneumonia in coughing newborns and toddlers?

Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.

A new clinical trial published by The Lancet says that HIV treatment through two injections every eight weeks kept the virus suppressed more effectively than daily tablets among adolescents, calling for efforts to make this treatment available and accessible worldwide.

The LATA trial, led by a team of researchers at University College London (UCL), examined 476 adolescents aged between 12 to 19 across five clinics in Kenya, South Africa, Uganda and Zimbabwe.

Participants were randomly assigned to continue daily antiretroviral tablets or switch to injections containing cabotegravir and rilpivirine.

All participants had already been taking HIV treatment for more than a year, had an undetectable amount of viral load and had no history of treatment failure. Most of the participants had acquired HIV at birth.

HIV Injections Prevented Viral Rebound

After 96 weeks, just two adolescents showed confirmed viral rebound, or 1%, in the injectable-treatment group. Comparatively, 15 adolescents, or 6%, among those taking daily tablets showed viral rebound. Viral rebound refers to the levels of HIV in the blood that increases again after being suppressed previously.

Maintaining an undetectable viral load is central to HIV treatment. It also reduces the risk of sexual transmission significantly.

The researchers found that the injectable treatment was not only effective at maintaining viral suppression but was preferred by adolescents.

Around 94% of participants receiving the injections said treatment every eight weeks was much easier and more convenient than taking medicine every day.

Professor Sarah Pett, chief investigator of the LATA trial at UCL, said, “HIV-positive adolescents as a group have historically done worse on antiretrovirals compared to adults. There is bullying and stigma associated with taking pills every day. Long-acting injectables taken every two months can help young people lead a more normal life.”

She added that the benefits seen in adolescents were stronger than previously observed in adults, where trials have generally shown that injections are no less effective than daily tablets.

Also read: Exclusive With Leading HIV Expert: What's Driving Rising HIV Cases Among India's Youth And How To Prevent It

Could Injections Help Treat HIV Better In Young People?

Taking HIV pills every day can be difficult for adolescents, particularly when its treatment is associated with stigma. They may have concerns about others discovering their HIV status, which could challenge the maintenance of a daily routine.

The weekly-injection approach removes the need to remember to take a pill every day. Instead, cabotegravir and rilpivirine are administered in a healthcare setting once every eight weeks. This could be particularly relevant in Africa, where most adolescents living with HIV reside.

“Nine out of 10 adolescents with HIV live in Africa, yet currently this treatment is not accessible to them,” Pett said.

Also read: Once-Weekly Oral Combination HIV Pill Shows Promise As Alternative to Daily Treatment

Accessibility To The Treatment Is Still A Challenge

Despite the promising results, researchers say that access to the groundbreaking treatment still remains a major challenge.

The HIV injections are more expensive than standard tablets as they remain under patent. Rilpivirine also requires refrigeration during storage and transport. Trained healthcare workers are needed to administer the injections every eight weeks.

The World Health Organization currently recommends that the injectable treatment must be used as an alternative for adults and adolescents who have successfully suppressed HIV on oral treatment as well as do not have active hepatitis B.

Dr Deborah Ford of UCL said, “The lack of availability of injectable treatments in Africa risks increasing inequalities in HIV care, leaving most people living with HIV without access to treatments that are available in high-income settings.”

A powerful veterinary drug has been lately spotted in Scotland's illegal drug supply, raising concern among health officials and addiction specialists about severe sedation, overdose-related deaths and dangerous withdrawal symptoms.

Medically known as medetomidine, the drug is used by veterinarians to sedate animals. It is strictly not approved for use in humans.

According to Public Health Scotland, the drug has been located in Scotland's unlawful drug supply and is most likely being mixed into drugs and peddled as heroin and benzodiazepines.

According to recent reports, medetomidine was detected in one in five heroin samples tested between March and June 2026, highlighting it has seeped deeply into various parts of the drug supply. It has been detected in several areas, including Lanarkshire, Falkirk, Dundee, Fife and the Highlands.

Also read: Alzheimer's Day: Why Can A Patient Remember An Event From Decades Ago But Forget What Happened This Morning?

What Is Medetomidine?

Medetomidine is a sedative that affects the alpha-2 receptors in the nervous system, producing profound sedation and slowing down several bodily functions, rendering the user in a ‘zombie-like’ state.

The UK's Advisory Council on the Misuse of Drugs has previously warned that medetomidine can cause severe sedation, reduced heart rate and other negative cardiovascular effects. In severe toxicity, people may require intensive care and mechanical ventilation.

Unlike an opioid overdose, naloxone does not reverse medetomidine's sedative effects. This is particularly concerning as the drug was found mixed with opioids like heroin.

Also read: US Teen's Death Sparks Warning Over Synthetic Drug Deadlier Than Fentanyl

Why Is It Being Called A ‘Zombie’ Drug?

The drug is being called a ‘zombie drug’ due to the effects it leaves due to excessive sedation and changed behaviour. After ingesting it, people may become extremely drowsy or unresponsive, while others may experience confusion, hallucinations or agitation. It may also slow their movements and reflexes down.

The bigger concern is the aftereffects of exposure. A recent study of 16 people with confirmed medetomidine exposure found that patients reported severe and unpredictable withdrawal symptoms, sometimes requiring hospital treatment.

Symptoms reported in the study included nausea, vomiting, shaking, rapid heartbeat, and dangerous high blood pressure.

Researchers also found that standard medications used to treat opioid withdrawal did not always adequately control the symptoms linked with medetomidine.

Also read: Donald Trump Wants Childhood Vaccines Split Into 5 Shots To Prevent Autism: But Is There Evidence?

More About The Drug

Public Health Scotland says that the drug has been detected in brown powders sold as heroin and white tablets sold as diazepam. As people may believe they are taking another drug, they may have no idea that a potent veterinary sedative is also entering their body. This could make tracking the drug supply difficult to predict.

Medetomidine belongs to the same broad class as xylazine, another veterinary sedative that has been increasingly detected in illegal drugs.

Xylazine has become notorious in the US for severe skin wounds linked with repeated exposure. Scientists do not yet know whether medetomidine results in the same effect in humans.

Doctors in Texas are seeing otherwise healthy young and middle-aged workers getting diagnosed with severe kidney disease and, in some cases, reaching kidney failure without the diabetes, high blood pressure or any other long-standing condition that commonly damage the kidneys.

The condition doctors suspect is chronic kidney disease of unknown etiology, or CKDu, a form of kidney disease that has been documented for decades among agricultural and manual workers in hot regions of Central America, Sri Lanka and India. Recent reports suggest similar cases may be going unrecognised in the US, particularly among vulnerable migrant workers.

What Is CKDu?

CKDu is a condition in which a person's kidney function progressively declines without the usual causes of chronic kidney disease.

Diabetes and high blood pressure are among the biggest causes of kidney disease globally. But CKDu presents differently as it been reported predominantly in relatively young workers who may have neither condition.

The disease can damage the kidney's filtering and tubular structures and gradually reduce its ability to remove waste and regulate fluids and electrolytes.

Currently, there are no specific tests or treatment options to tackle CKDu. Doctors generally investigate and rule out other causes of kidney damage while considering a person's occupation and environmental exposures.

Also read: Dialysis Demystified: When Is It Necessary, How Does It Work And Can It Be Avoided?

Young Workers Are At Risk

Geographical location is one of the strongest clues that helps doctors confirm CKDu diagnosis. In Central America, the disease has been particularly associated with people doing strenuous agricultural work in hot and humid conditions.

Similar concerns have emerged among outdoor workers in Texas, including people working in construction, roofing and other physically demanding jobs.

Repeated heat stress and dehydration are among the leading suspected contributors. When someone repeatedly loses large amounts of fluid through sweating and does not adequately replace it, the kidneys can come under considerable stress.

Researchers are also investigating whether pesticides, contaminated water, heavy metals, infections and frequent use of painkillers like NSAIDs could contribute. However, the definite cause of CKDu still remains unknown.

Also read: Cefepime: Antibiotic Used For Pneumonia, UTI Linked To Higher Death Risk In Adults

CKDu Remains Silent Until Significant Kidney Damage Has Occured

CKDu can be particularly dangerous because people may have few obvious symptoms during the early stages. Many affected workers discover the problem through blood or urine tests rather than because they feel seriously ill.

By the time symptoms like severe fatigue, weakness, nausea, sleep problems or breathlessness develop, kidney function may already be substantially reduced.

A US study based on patients receiving emergency dialysis at a Texas county hospital found that 17% had clinically diagnosed, suspected or possible CKDu-related kidney failure.

Climate Change Could Be Another Contributing Factor

Researchers are increasingly looking into the connection between extreme heat and kidney health. The National Institute of Environmental Health Sciences says CKDu has emerged mainly among agricultural workers in hot, humid regions and notes that rising global temperatures could increase exposure to severe occupational heat stress.

But scientists are still trying to determine exactly how heat, dehydration and other workplace exposures interact to result in last-stage kidney failure. That uncertainty is one reason why CKDu remains such a difficult disease to study.

A 2026 International Society of Nephrology report noted that proposed causes such as heat stress may contribute to kidney injury without necessarily explaining exactly how the disease begins.