Ultra-Low-Dose CT Scans May Help Early Detection Of Pneumonia

Updated Mar 19, 2025 | 09:20 AM IST

SummaryCT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation.
Ultra-Low-Dose CT Scans May Detect Pneumonia in At-Risk Patients

Credit: Canva

Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.

"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.

Study Gives Solution To This

To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.

"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.

How Can You Detect Pneumonia?

Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:

Coughing with or without cough

Fever

Chills

Trouble breathing

Chest pain, especially when breathing deeply or coughing

Sweating or chills

Rapid heart rate

Loss of appetite

Bluish skin, lips, and nails

Confusion.

How to detect Pneumonia in coughing newborns and toddlers?

Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.

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Legionnaires’ Disease Outbreak Investigation In Toronto After 6 Cases Surface: What We Know

Updated Aug 18, 2026 | 07:11 AM IST

SummaryHealth officials are investigating a Legionnaires’ disease outbreak in Toronto after at least six people were sickened by the bacteria.
Toronto Legionnaires’ Disease Outbreak Under Investigation Near Downtown Core: What We Know

Credit: AI

Toronto Public Health is investigating a Legionnaires’ disease outbreak near the downtown core after six confirmed cases were identified among people who live, work or recently visited the area.

The cases are clustered within roughly a one-kilometre radius of Bathurst Street and Dupont Street, with patients developing symptoms between July 2 and July 26, according to Toronto Public Health. Officials are now carrying out environmental inspections and collecting samples to determine where the Legionella bacteria may have come from.

The source has not been identified yet, and Toronto Public Health said the overall risk to the public remains low because Legionnaires’ disease generally does not spread from person to person.

Did A Cooling Tower Cause Toronto's Legionnaires' Outbreak?

Also read: Legionnaire’s Disease NYC Outbreak: 3 Dead, 67 Sick; Health Authorities Have Identified ZIP Codes Linked With Cluster

Investigators believe this could be one of the possibilities but no source has been confirmed yet. Toronto Public Health is conducting on-site inspections to identify potential sources. Precautionary control measures have already been implemented.

Officials are also investigating whether the current cluster could be connected to an earlier outbreak at Castleview Wychwood Towers, a nearby long-term care facility where five cases were confirmed in July.

The possibility of a building water system is particularly relevant because Legionella grows more easily in warm, stagnant water, especially when disinfectant levels are inadequate or systems contain biofilm and sediment.

Toronto Has Already Seen A Rise In Legionella Cases

The current investigation comes against a broader increase in legionellosis in Ontario. Public Health Ontario reported 94 laboratory-confirmed cases between January 1 and June 16, 2026. Of these, 35 were linked to a cluster or outbreak, compared with an average of just 3.6 outbreak-associated cases during the same period from 2021 to 2025.

The province also recorded an earlier-than-expected increase in cases in April, when the rate was 1.8 times higher than the average for the previous five years.

For Toronto residents, however, health officials are stressing that the current investigation does not mean there is a widespread public health emergency.

What Is Legionnaires’ Disease?

Also read: Legionnaire’s Disease Outbreak Kills 2 And Sickens 58 In New York City- Know Symptoms And Risk

The bacteria become a health concern when they multiply in human-made water systems. These can include cooling towers, large plumbing systems, hot tubs, showers, humidifiers and decorative fountains.

People can become infected by breathing in tiny droplets or vapour containing the bacteria. Drinking contaminated water is not considered the usual route of infection, and people generally do not catch Legionnaires’ disease simply by being around someone who has it.

Who Is Most At Risk?

Most healthy people exposed to Legionella do not develop severe disease. However, the risk of serious illness is higher among:

  • Older adults
  • People who smoke
  • People with chronic lung disease or other underlying health conditions
  • People with weakened immune systems

Symptoms can include fever, cough, shortness of breath and muscle aches, and the infection can become severe enough to require hospitalisation. Legionnaires’ disease can also be fatal, particularly in vulnerable people.

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Nestlé Customizes Drinks For Ozempic, Wegovy Consumers: What Are Protein And Nutrition Needs of GLP-1 Users?

Updated Aug 17, 2026 | 10:00 PM IST

SummaryAppetite suppression from GLP-1 drugs can create nutritional gaps, with potential consequences such as irreversible nerve damage, including peripheral neuropathy and cognitive impairment. Unaddressed deficiencies among consumers can cause tingling, numbness, brain fog and unexplained fatigue.
Nestlé Customizes Drinks For Ozempic, Wegovy Consumers: What Are Protein And Nutrition Needs of GLP-1 Users?

Credit: AI Image

Amid increasing uptake of GLP-1 weight-loss drugs such as Ozempic and Wegovy, FMCG major Nestlé has realigned its nutritional drinks to meet the changing nutritional needs of users.

The company has announced plans to roll out new protein drinks designed for people taking GLP-1 weight-loss medications such as Ozempic and Wegovy in the US, Asia and Australia. Since these drugs curb appetite and can contribute to issues such as muscle loss and “Ozempic face,” Nestlé wants to help users stay healthy while their eating habits change, Reuters reported.

To better understand their nutritional needs, Nestlé is using AI to study clinical research and real-world consumer needs. It is also expanding its high-protein offerings to support muscle health, along with collagen-added products in its Vital Proteins line for skin and hair.

What Are the Protein and Nutrition Needs of GLP-1 Users?

Also read: World Prediabetes Day: Can ‘Food Noise’ Affect Blood Sugar And Weight?

The number of people using GLP-1 drugs is growing rapidly, with about 16 million Americans currently taking the medications for weight loss. Globally, use remains much smaller than the potential eligible population, with access and affordability still major barriers.

But do GLP-1 users need more protein?

Dr. Navin Gnanasekaran, Longevity Physician, Apollo Hospitals, told HealthandMe that for individuals on GLP-1 receptor agonists, rapid weight loss can lead to a significant reduction in both fat and lean muscle mass. Alarmingly, up to 30-40% of the total weight lost can be muscle.

“Prioritizing protein intake and structured resistance training is absolutely critical to counteract this muscle depletion,” he said.

How Much Protein Do GLP-1 Users Need?

Read More:GLP-1 Weight Loss Drugs Ozempic, Wegovy, Mounjaro Tied To Over 60 Reported Deaths In Australia

Dr. Navin said that a daily intake of at least 1.0 to 1.5 grams of high-quality protein per kilogram of body weight is recommended. Lean meats, eggs, dairy and plant-based proteins can help meet these needs.

He also recommended strength training to preserve muscle tissue. Together, adequate protein and resistance training can help support muscle mass and maintain the basal metabolic rate (BMR), which may help prevent weight regain.

Dr. Praveen Gupta, Chairman, Marengo Asia International Institute of Neuro and Spine (MAIINS), Marengo Asia Hospitals, told HealthandMe that a large number of people in India eat vegetarian diets that are already low in B12, iron and vitamin D. These nutritional gaps can quietly widen when food intake is reduced with GLP-1 drugs.

For people following vegetarian diets, familiar kitchen staples such as paneer, dal, soya chunks, hung curd, sprouts and eggs, spread across the day, can help meet protein targets without animal meat.

How Do GLP-1 Drugs Work?

Dr. Praveen said these drugs work by slowing digestion and dialing down “food noise” — the constant mental chatter around eating — which naturally cuts how much a person consumes, sometimes by half.

GLP-1 receptors are located not just in the gut but throughout the central nervous system, including regions such as the hypothalamus and hippocampus that receive direct input from GLP-1-producing neurons in the hindbrain. This is part of why appetite suppression can be so powerful: the drugs act on the brain’s hunger circuitry, in addition to slowing digestion.

Do GLP-1 Drugs Increase the Risk of Nutritional Deficiencies?

The overall appetite suppression caused by these medications can increase the risk of vitamin deficiencies. Constipation is also a common GLP-1 side effect due to decreased dietary fiber intake.

Good hydration, planned nutrient-dense meals and adequate fiber can help offset these effects.

Routine monitoring of essential micronutrients, particularly vitamin D, B12 and iron, is highly advised to ensure patients achieve sustainable, healthy weight loss without compromising their long-term nutritional well-being.

Why Protein Matters

  • Reduced food intake: Appetite suppression from GLP-1 drugs can create nutritional gaps, with potential neurological consequences.
  • Vitamin B12: Deficiency can cause irreversible nerve damage, including peripheral neuropathy and cognitive impairment.
  • Warning signs: Unaddressed deficiencies can cause tingling, numbness, brain fog and unexplained fatigue.
  • Muscle loss: A significant share of weight lost on GLP-1 medications can be lean muscle rather than fat if adequate protein intake and physical activity are not prioritised.
  • Nutrition matters: Inadequate nutrition can affect both muscle and nerve tissue, making adequate protein and essential micronutrients important during weight loss.

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Tylenol, Other Medications Linked To 400% Rise In Liver Injuries In US

Updated Aug 17, 2026 | 06:35 PM IST

SummaryFemales had higher rates of acetaminophen-associated liver injury than males. Suspected suicide was the most common reason for exposure in both sexes, as per data from poison centers.
Tylenol, Other Medications Linked To 400% Rise In Liver Injuries In US

Credit: AI Image

Liver injuries reported to US poison centres increased by nearly 400% between 2000 and 2024, with acetaminophen, sold under brand names such as Tylenol, the most frequently implicated substance, according to a study.

The study analysed poison-centre calls involving liver injuries linked to “xenobiotics”—foreign substances not naturally found in the human body. These include medications, food additives, alcohol and environmental pollutants.

Acetaminophen Among Leading Causes

Also read:‘Entirely Unverified Retatrutide’ Being Sold on Black Market: Lilly Sues 6 US Companies

Researchers identified 220,160 cases of xenobiotic-related liver injury over the 24 years. Population-adjusted exposure rates increased from 10.9 per million people to 52.9 per million.

More than 80% of the liver injury cases required inpatient care, with medications accounting for the majority of cases. Acetaminophen was the substance most frequently implicated.

“Liver injuries reported to poison centers have increased substantially over the past 25 years, with acetaminophen emerging as a growing contributor,” said Christopher P. Holstege of UVA Health.

Acetaminophen Exposure Trends

The study found that exposures involving acetaminophen-containing combination drugs decreased by 60%-85% after the US Food and Drug Administration capped the amount of acetaminophen allowed in combination prescription products.

However, potentially harmful exposures to acetaminophen alone increased steadily over the 24 years. The findings suggest that regulatory action reduced liver injuries linked to combination products, while acetaminophen alone remained a leading contributor to poison-centre-reported liver injuries.

Females had higher rates of acetaminophen-associated liver injury than males. Suspected suicide was the most common reason for exposure in both sexes.

Alcohol and Other Substances

Read More: What Trump’s Childhood Vaccine Order Means: When Will It Take Effect?

Alcohol was the second most common cause of liver injuries, although it was far less common than acetaminophen. Alcohol-related injuries were more frequent in men than women but increased in both sexes during the COVID-19 pandemic.

Researchers also identified increases in liver injuries linked to stimulants and street drugs, herbal and dietary supplements, and environmental toxins. However, these were much less common than injuries associated with acetaminophen and alcohol.

“Medications should always be taken as directed by clinicians and per pharmaceutical label instructions,” Holstege said. He also advised caution with emerging substances that are not regulated.

Why Tylenol Is Linked To Liver Injuries

  • Research shows tylenol is safe at recommended doses, but exceeding 4,000 mg per day for adults—or combining it with alcohol or other medications containing the drug—can overwhelm the liver's ability to process it safely, leading to acute liver failure.

    "Acetaminophen is widely available without a prescription, and it’s contained in many combination medications — more than 600. It’s likely that many people taking acetaminophen do not realize they’re taking too much since, for example, you take acetaminophen tablets for the achy feeling that comes with a cold and also use a combination cough medicine that contains acetaminophen," Howard E. LeWine, Chief Medical Editor, Harvard Health said.

    Tylenol and Autism Claims

    The debate has also triggered legal action, as Texas sued Kenvue over alleged failures to warn pregnant consumers, and a US appeals court this month revived more than 500 private lawsuits making similar claims.

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