Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.

"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.

Study Gives Solution To This

To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.

"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.

How Can You Detect Pneumonia?

Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:

Coughing with or without cough

Fever

Chills

Trouble breathing

Chest pain, especially when breathing deeply or coughing

Sweating or chills

Rapid heart rate

Loss of appetite

Bluish skin, lips, and nails

Confusion.

How to detect Pneumonia in coughing newborns and toddlers?

Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.

Air pollution is usually discussed in terms of lungs, heart and breathing problems. But scientists are also looking at brain that could also be taking a hit from the polluted air.

A new study has found that using a HEPA (High-Efficiency Particulate Air) air purifier at home for just one month showed better performance on an executive function test among adults aged 40 and above.

Participants in this age group completed the test about 12% faster after spending a month breathing air filtered by a HEPA purifier compared to an ordinary one.

The study was published in Scientific Reports and based on 119 people aged 30 to 74 living in Somerville, Massachusetts, an area surrounded by major highways and exposed to relatively high levels of air pollution from the traffic.

Brain May Also Ne Affected By Air Pollution

Fine particulate matter from traffic pollution is small enough to penetrate deep into the respiratory system. But its effects may not stop at the lungs.

Earlier research has linked particulate pollution with cardiovascular disease and neurological conditions like Alzheimer's and Parkinson's disease. Exposure to air pollution has also been linked with decline in cognitive function.

With this study, researchers wanted to examine whether reducing people's exposure to these harmful particles indoors could make a difference to how their brains function.

Also read: Exposure To Air Pollution May Harm Male And Female Fertility, Expert Reveals

What Did The Researchers Find?

The participants were randomly assigned to use either a real HEPA purifier or a sham purifier at home for one month. The sham device looked and operated like the real purifier but did not contain the air-cleaning filter.

After a month, participants completed tests examining different aspects of cognitive function, including visual memory, motor speed, mental flexibility and executive function. The groups then switched purifiers after a month-long break.

Among participants aged 40 and above, the researchers found that they completed the test that measured mental flexibility and executive function 12% faster after using the real HEPA purifier.

Also read: Delhi’s Air Pollution May Be Harming The Brain, Not Just The Lungs: Report

Effects Of Air Purifier On The Brain

Researchers say the exact mechanism is not known, but one possibility indicates that the particulate matter may have an effect on the brain's white matter.

White matter acts somewhat like the brain's communication wiring. It helps different brain regions communicate with one another by supporting the connections between nerve cells.

Older research has suggested that air pollution may reduce white matter and particularly affect brain regions involved in executive function and mental flexibility, the same areas in which the researchers observed improvement after air purification.

Air pollution can also affect the cardiovascular system. Since the brain depends heavily on a continuous supply of oxygen-rich blood, damage to blood vessels could indirectly affect brain function. But researchers stress that these are simply possible explanations, not findings directly established by this study.

Who Could Benefit The Most?

The study's findings were particularly based on people aged 40 and older. Researchers noted that previous evidence suggests the effects of air pollution on cognition become more evident around this age.

People living close to busy highways and major roads may also have more reason to consider indoor air filtration because traffic is one of the biggest sources of particulate pollution.

Additionally, the participants used the purifier for only one month. Researchers therefore do not yet know whether the improvement would persist, become larger or disappear with longer-term use.

India must move beyond treating hemophilia—a genetic bleeding disorder—only after bleeding episodes and focus on preventing bleeding and its complications, health experts said at the UP-Hemophilia Conclave 2026.

Hemophilia is a rare bleeding disorder where blood does not clot properly, even for minor injuries. It is caused by an error in a specific gene on the X chromosome, leading to a deficiency or absence of clotting factors.

The country has the world's second-largest population of people with hemophilia, who experience spontaneous and traumatic bleeding due to low or very low levels of clotting factors.

The World Federation of Hemophilia (WFH) reported nearly 28,000 diagnosed and registered Persons with Hemophilia (PwH) in India as of 2026, including more than 24,000 with Hemophilia A. However, the estimated prevalence could be as high as 1,36,000, suggesting many cases may remain undiagnosed or misdiagnosed. In Uttar Pradesh, around 7,700 PwH are diagnosed, including approximately 5,500 with Hemophilia A.

Although India has expanded access to modern diagnosis and treatment, including gene therapy trials and non-factor therapies (NFTs) such as emicizumab, experts said preventive care needs to be strengthened.

Experts Call For Shift To Preventive Care

Also read: Why India Must Shift Towards Prophylaxis Care For Hemophilia

Hemophilia patients should be able to lead normal lives and be managed like people with chronic conditions such as diabetes and hypertension, with regular replacement treatment to prevent complications, said Prof A. K. Tripathi, Clinical Hematologist and former Director, RMLIMS, Lucknow.

“At present, patients largely rely on reactive treatment, where therapy is given only after a bleeding episode. This approach is neither appropriate nor effective. They do not just need treatment when they bleed; they need treatment that prevents bleeding in the first place. The only way forward is to start prophylaxis,” he said.

Why Is Prophylaxis Important?

Repeated joint bleeding can cause lasting damage, making it difficult to walk and, in severe cases, leaving patients chair-bound or bed-bound.

Regular replacement treatment, or prophylaxis, can protect joints and muscles and improve quality of life, said Dr S. P. Verma, Professor and Head, Department of Clinical Hematology, King George's Medical University (KGMU), Lucknow.

“Preventive treatment through regular replacement therapy (prophylaxis) has emerged as the global standard of care. This changing treatment landscape presents an opportunity to strengthen preventive care and improve long-term outcomes for patients,” said Dr Nita Radhakrishnan, Professor and HOD, Pediatric Hematology and Oncology, Post Graduate Institute of Child Health (PGICH), Noida.

Access And Availability Remains A Concern

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Vineet Manchanda, Secretary, Hemophilia Society, Lucknow, and Manoj, Hemophilia Federation of India (HFI) North and Agra Chapter, flagged that “Factor VIII, a clotting factor that can prevent bleeding in Hemophilia patients, is very expensive, and the government hospital’s supply is erratic, making availability a major issue".

They also stressed the importance of physiotherapy alongside newer therapies such as prophylaxis.

The experts also highlighted the financial burden of complications, including costly knee or hip replacement surgeries.

Access remains a major concern, with many patients travelling long distances for treatment. “Despite the resources, manpower and factors being invested, we are not achieving the desired results,” Prof Tripathi said.

Experts also called for better use of available budgets to identify and support patients who need treatment the most.

Organized under the aegis of the Uttar Pradesh Hematology Group (UPHG), the UP-Hemophilia Conclave 2026 was held in Lucknow under the theme ‘Uniting Care. Improving Lives.’ It brought together hematologists, physicians, researchers, pathologists, healthcare professionals from hemophilia treatment centers, policymakers and patient groups.

Days after a rare cancer cluster in California's Ladera Ranch made headlines, another revelation has added to the mystery. An unusual number of children and young adults got diagnosed with Ewing sarcoma, a rare type of cancer.

According to Los Angeles Times, between 2013 and 2024, at least six cases of Ewing sarcoma surfaced, leaving the families of patients knee-deep in questions.

According to the American Cancer Society, the cancer is so rare that only 200 children and teenagers are diagnosed in the United States every year.

Mystery Behind Rare Cancer Cluster In Ladera Ranch Deepens

Just when the families of patients were looking for answers, another layer of mystery unraveled after a couple of 20-year-old handwritten notes emerged, signaling towards a probable cause behind the cancer cases.

The notes talk about an oil well at the site. According to The New York Post, the notes appear twice on the Department of Conservation permit, and state, "This well is not to be built over without further considerations."

State oil and gas supervisor William F Guerard Jr, acting state oil and gas supervisor Kenneth Henderson and deputy supervisor RK Baker signed the final report after the well was sealed on February 26, 2002.

The memos warning that no structures must be constructed above the well were reportedly written by engineer Floyd Leeson. They do not reveal why such a warning about the well was issued. Another note had an arrow pointing at the message, with the phrase: "Put on final letter."

According to Los Angeles Times, Henderson could not recall why such a warning was issued, although he believes the way the well was sealed might not be "up to the current standards." Meanwhile, the Department of Conservation said that the notes could have been a "clerical error."

Also read: Cancer Should Be Made Notifiable In India, Say Experts: Here’s Why

A Cancer So Rare That The Cases Caught Attention

Symptoms can initially be easy to dismiss because they may resemble a sports injury or ordinary growing pains. They include persistent bone pain, swelling or a lump, unexplained fever, fatigue or a bone that breaks after relatively minor trauma can sometimes signal the disease.

The cancer can metastasize quickly, which is why persistent or unexplained symptoms need medical evaluation.

Also read: New Clinical Trial Shows Promise In Non-Surgical Treatment Of Early-Stage Rectal Cancer

Can Environmental Factors Contribute To Ewing Sarcoma Risk?

Documents related to the abandonment of an old oil well reportedly contain a handwritten warning from about 20 years ago regarding the development of the site. This prompted fresh questions about what was known about the land before the modern community was built.

There are also concerns about possible pesticide and herbicide exposure, with residents previously urging authorities to investigate environmental factors.

However, none of these potential exposures have been shown to cause the Ewing sarcoma cases in Ladera Ranch. Even though doctors are concerned, they are of the opinion that environmental factors cannot be solely tied to Ewing sarcoma.