Credit: Canva
Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
Credit: AI
Amid an expanding outbreak, Florida has confirmed its first dengue-related death in the Tampa Bay region. It is the first death due to dengue in Tampa Bay in almost a century, while Florida health officials have confirmed this as the state’s first dengue-related death of 2026.
The latest reports show the newest figures that indicate 152 locally acquired dengue cases as of September 12, with 134 in Hillsborough County.
Florida’s dengue outbreak has turned deadly as with health officials have confirmed the state’s first dengue-related death of 2026.
The Florida Department of Health confirmed the death on September 18. The victim was an 80-year-old Hillsborough County woman who died on September 4. Her death marks the first known dengue-related fatality in the Tampa Bay region in nearly a century.
The latest state data, covering cases through September 12, show 152 locally acquired dengue infections across Florida this year, including 134 in Hillsborough County.
That means nearly 90% of the state's locally acquired cases have been concentrated in the county, which has emerged as the epicentre of the outbreak.
“This is wildly unusual for us,” Chris Wilkerson, a spokesperson for Hillsborough County, said.
Also read: QDENGA: India’s First Approved Dengue Vaccine May Hit Shelves In 2027; How Effective Is It?
Dengue is a viral infection transmitted mainly by infected Aedes aegypti and Aedes albopictus mosquitoes. These mosquitoes are established in Florida and can spread the virus after biting an infected person.
Majority of the dengue infections reported in the continental US were linked with international travel. But Florida has increasingly recorded locally acquired infections, meaning people contracted the virus without travelling to a dengue-endemic country.
The state reported its largest number of locally acquired dengue infections in 2023, at nearly 200. With 152 cases already recorded this year, 2026 has become the state's second-highest year for locally acquired infections.
Also read: Delhi Dengue Cases Rise In September: Is Weather Fueling The Surge?
Most people infected with dengue either have no symptoms or develop a relatively short-lived illness with fever, headache, muscle and joint pain, nausea and rash. But a small number of people can develop severe dengue, particularly around the time the fever begins to subside.
Warning signs include severe abdominal pain, persistent vomiting, bleeding or unusual bruising, difficulty breathing, extreme weakness and restlessness.
Severe dengue may also cause plasma leakage, shock, severe bleeding and organ damage, which can become fatal without prompt medical care.
In the Florida woman's case, her death certificate listed dengue infection, septic shock and multi-organ failure as causes, according to the Tampa Bay Times.
Hillsborough County normally sees only a handful of dengue cases, making the current cluster seems to be highly unusual. Mosquito-control teams have increased aerial and ground surveillance and spraying, inspecting properties for stagnant water where mosquitoes can breed.
Recent mosquito sampling has not detected dengue virus in some of the latest collections, which officials say could indicate that transmission is beginning to decline. But experts caution that the mosquitoes capable of spreading dengue may still remain in Florida.
Michael von Fricken, an associate professor of environmental and global health at the University of Florida, said the state's recurring mosquito population means dengue may become “somewhat the new normal.”
Florida health officials are urging residents to use mosquito repellent, wearing long sleeves and trousers, and removing stagnant water from around homes.
Credit: X
In the trailer for the eighth season of The Kardashians, Kim Kardashian revealed that she has been diagnosed with esophagitis, a condition involving inflammation and irritation of the esophagus. The conversation sparked memories of her father Robert Kardashian, who died of esophageal cancer in 2003.
In the trailer, someone asks her, “Didn't your father ... isn't it what he died of?” to which she responds, “Yeah.”
Her mother, Kris Jenner, is also seen becoming emotional. Kardashian is shown in a hospital bed, although the trailer does not reveal the exact cause or severity of her esophagitis or any procedure she may have undergone.
But it is important to clarify that esophagitis and esophageal cancer are two different conditions.
Esophagitis is a condition in which the lining of the esophagus, the tube that carries food and liquids from the mouth to the stomach, becomes inflamed.
There are several possible causes for the inflammation of the esophagus. The most common is gastroesophageal reflux disease (GERD), a condition in which stomach acid flows back into the esophagus repeatedly. Other causes include certain medications, infections and allergic or conditions related to immune system.
Symptoms can include heartburn, chest pain, painful or difficult swallowing, coughing, hoarseness and a sore throat.
The treatment for esophagitis depends on what is causing the inflammation and can include medicines that reduce stomach acid, treatment for an infection or changes to diet and other habits. The condition is often manageable with treatment.
Esophagitis itself does not mean a person will develop esophageal cancer. The concern refers to when chronic acid reflux continues for years. Repeated exposure to stomach acid can damage the esophageal lining and, in some people, lead to Barrett's esophagus.
Barrett's esophagus involves changes in the cells lining the lower esophagus and is associated with an increased risk of esophageal adenocarcinoma, one of the major types of esophageal cancer. However, most people with Barrett's esophagus do not develop cancer.
Rather, in some people, long-standing reflux can cause chronic damage, which can lead to Barrett's esophagus, which in turn is associated with a higher cancer risk.
Also read: Busy Philipps Reveals She Had Surgery To Remove A Rare Brain Tumour: What Is Oligodendroglioma?
According to reports, Kim Kardashian's father Robert Kardashian died from esophageal cancer in September 2003 at the age of 59, only about two months after his diagnosis. This family history makes Kim's diagnosis particularly significant.
However, there is currently no public information showing that her esophagitis is hereditary or that it is connected to the cancer her father had. Her diagnosis also does not establish that she has Barrett's esophagus or esophageal cancer. The trailer does not disclose those details.
The Kardashian family has nevertheless remained involved in awareness about esophageal health since Robert's death. In 2019, the family helped establish the Robert G. Kardashian Center for Esophageal Health at UCLA, dedicated to research, treatment and education about diseases of the esophagus.
Persistent difficulty swallowing, painful swallowing, unexplained weight loss, recurrent vomiting, bleeding or discomfort in chest should not simply be dismissed as normal acidity.
Doctors may use tests such as an upper endoscopy to examine the esophagus and determine whether inflammation, structural changes or other abnormalities are present. Persistent inflammation, particularly when driven by untreated chronic reflux, can sometimes signal a problem that needs medical evaluation and follow-up.
Credit: iStock
India’s first approved dengue vaccine, QDENGA, could be available in the private market by the first half of 2027, Dr Reddy’s Laboratories said. The company is partnering with Japan’s Takeda to promote and distribute the vaccine in India.
“Subject to the completion of applicable processes with local authorities, the vaccine is anticipated to become available in the first half of 2027,” the companies said.
Also read: Delhi Dengue Cases Rise In September: Is Weather Fueling The Surge?
India’s dengue burden has risen 11-fold over the past two decades. Rapid urbanization, climate change and mosquito breeding have contributed to the growing public health challenge.
A nationwide ICMR dengue surveillance study found that all four dengue virus serotypes — DENV-1 to DENV-4 — are circulating across multiple regions. About one in 14 patients had concurrent infections with multiple serotypes.
QDENGA received market authorization from the Drug Controller General of India (DCGI) in July to prevent dengue in people aged 4 to 60 years.
According to Takeda, it can be given regardless of previous dengue infection and does not require pre-vaccination testing.
Since 2022, QDENGA has been approved in 43 countries across Asia, Latin America and Europe. It is also part of Brazil’s National Immunization Program and public immunization programs in Argentina, Colombia and Indonesia.
READ: Dengue Is Spreading Beyond Monsoons And Into New Regions Across India, Says Expert
QDENGA is designed to protect against all four dengue virus serotypes, regardless of previous dengue exposure.
The DCGI approval is supported by Takeda’s clinical program, which included 19 Phase 1, 2 and 3 trials involving more than 28,000 participants.
The pivotal Phase III TIDES trial included more than 20,000 participants across eight countries. Key findings included:
An Indian Phase III trial involving people aged 4 to 60 years also found the vaccine safe, well tolerated and immunogenic.
QDENGA (TAK-003) is a live-attenuated tetravalent dengue vaccine targeting all four dengue virus serotypes.
It is given as two 0.5 mL subcutaneous doses, three months apart. The vaccine uses a DENV-2 backbone with structural proteins from DENV-1, DENV-3 and DENV-4.
The WHO recommends QDENGA for use in dengue-endemic settings without pre-vaccination screening. It is also WHO-prequalified for procurement through agencies including UNICEF and PAHO.
Dr Reddy’s will handle promotion and distribution in the private market, while Takeda will retain rights to promote and distribute QDENGA in India’s public market.
In February 2024, Takeda partnered with Hyderabad-based vaccine maker Biological E to expand QDENGA production.
Biological E plans to manufacture 50 million doses annually, supporting Takeda’s goal of producing 100 million doses globally each year by the end of the decade.
The company’s production will focus heavily on multi-dose vials for public health sectors and National Immunization Programs in dengue-endemic countries globally.
© $2026 Times Horizon Private Limited