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Low-dose CT chest scans could help detect pneumonia in at-risk patients while exposing them to only small amounts of radiation, a new study has found. The research, published in Radiology: Cardiothoracic Imaging, shows that ultra-low-dose scans can effectively detect pneumonia in patients with compromised immune systems, enabling doctors to treat the infection before it becomes life-threatening. According to the researchers, these scans expose patients to just 2% of the radiation dose used in a standard CT scan.
"This study paves the way for safer, AI-driven imaging that reduces radiation exposure while preserving diagnostic accuracy,” lead researcher Dr Maximiliano Klug, a radiologist with the Sheba Medical Center in Ramat Gan, Israel, said in a news release. He added that CT scans are the gold standard for detecting pneumonia but there are concerns regarding the risk posed by repeated exposure to radiation. There is a solution- ultra-low-dose CT scan. However, the problem is that these scans can be grainy and hard to read, researchers said.
Study Gives Solution To This
To overcome that, Klug's team developed an AI program that could help "de-noise" low-dose scans, making them sharper and easier to read. Between September 2020 and December 2022, 54 patients with compromised immune systems who had fevers underwent a pair of chest CT scans -- a normal dose scan and an ultra-low-dose scan. The AI program cleaned up the low-dose scan, and then both sets of images were given to a pair of radiologists for assessment. Radiologists had 100% accuracy in detecting pneumonia and other lung problems with the AI-cleaned low-dose scans, but 91% to 98% accuracy in examining the scans that hadn’t been improved through AI, results show.
"This pilot study identified infection with a fraction of the radiation dose," Klug said. "This approach could drive larger studies and ultimately reshape clinical guidelines, making denoised ultra-low dose CT the new standard for young immunocompromised patients.
How Can You Detect Pneumonia?
Pneumonia is a lung infection that causes the air sacs in the lungs to fill with fluid or pus and can be caused by bacteria, viruses, or fungi. The symptoms can range from milk to severe, which includes:
Coughing with or without cough
Fever
Chills
Trouble breathing
Chest pain, especially when breathing deeply or coughing
Sweating or chills
Rapid heart rate
Loss of appetite
Bluish skin, lips, and nails
Confusion.
How to detect Pneumonia in coughing newborns and toddlers?
Pneumonia can severely affect newborns and young children as their lungs are comparatively more sensitive. As per Dr Goyal, young children can cough for various reasons including seasonal infections and tonsillitis, which is very common in this age group. But if they look visibly irritable and have poor sleep patterns, then parents must reach out to an expert. "I am not saying that parents must visit a hospital but any local paediatrician would be able to detect pneumonia in your kid.
Credit: X/Instagram
Longevity expert and millionaire Bryan Johnson has revealed that he has been diagnosed with autoimmune gastritis (AIG), a condition in which the immune system attacks the stomach lining.
In a post on X, Johnson, known for his radical experiments, including receiving blood transfusions from his teenage son, said he believes years of eating sugary cereals, drinking soda, consuming fast food and experiencing chronic stress contributed to the development of his autoimmune conditions.
Calling it a "bad news", the millionaire said: "I have an autoimmune disease. My stomach is eating itself". He added that "2–5% of people have this, too. Likely more, because it hides".
“As a kid, I ate sugar cereal, drank sugary soda, and gobbled down fast food. I had a few healthy years in my early 20s, but then became a young father of three and began building a business. Juggling that stress and grind, I let my health slip and gained 40 lbs,” he wrote.
He added that he later developed chronic depression and believes that during this period, his body began an autoimmune process affecting both his thyroid and stomach lining.
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Johnson said he was diagnosed with hypothyroidism at the age of 21 during a routine blood test. He has since managed the condition with levothyroxine and Armour Thyroid.
“They are the hormones my body should be producing on its own, but wasn’t. By taking these pills daily, my body was able to operate as though my thyroid was functioning properly.”
He said his stomach had also begun attacking itself, but the condition went undetected because he had no symptoms. It was only discovered in May.
Johnson noted that autoimmune gastritis can cause irreversible damage, including nutritional deficiencies, anemia, and an increased long-term risk of stomach cancer.
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Johnson said he had persistently low ferritin levels for the past 11 years despite not having anemia.
“We continually tried to raise my iron levels with food and supplementation, but nothing would work.”
He said he followed a plant-based diet, trained intensely, used a sauna and hyperbaric oxygen therapy, and took iron supplements, but his iron levels remained low.
A colonoscopy ruled out slow gastrointestinal bleeding, while an upper endoscopy with five stomach biopsies revealed early autoimmune gastritis. The biopsies showed early atrophy confined to the stomach's acid-producing lining, while
the rest of the stomach remained unaffected.
“So this was never one problem. It was three, linked to one another: the iron deficiency, the autoimmune gastritis driving it, and the autoimmune thyroid disease alongside it.”
Johnson said he has undergone a large blood draw to sequence more than one million individual immune cells.
According to him, the goal is to identify the specific immune cell clones attacking his stomach lining. He compared immune cells to soldiers carrying unique "keys," explaining that the advanced sequencing technology can identify the rogue immune cells responsible for autoimmune gastritis.
Johnson said that once those immune cells are identified, the findings will help determine the most appropriate therapy to target and suppress the autoimmune attack.
Autoimmune gastritis (AIG) is a long-term autoimmune disorder in which the body's immune system mistakenly attacks the stomach's parietal cells, which produce stomach acid, as well as intrinsic factor, a protein essential for absorbing vitamin B12. Over time, this damages the stomach lining and reduces the body's ability to absorb iron and vitamin B12, increasing the risk of nutrient deficiencies.
In many people, symptoms are caused more by these nutritional deficiencies than by inflammation of the stomach itself.
Common symptoms include:
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The Ebola outbreak in DR Congo has risen to 1,427 cases, while the death toll has climbed to 440, according to the latest government data.
More than 609 patients are hospitalized in Congo, while many have also recovered. Uganda has so far reported 20 confirmed cases and two deaths. There has also been one case in France and another in a US citizen medically evacuated to Germany, both believed to have been imported from areas affected by the ongoing outbreak.
The Ebola virus disease, caused by the Bundibugyo strain, has no approved vaccine or treatment.
"Even without approved therapeutics, people are recovering from this disease, but, of course, we could save many more lives with safe and effective therapeutics in our toolkit," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General.
He said this while announcing the launch of the clinical trial of two therapeutics, with the enrolment of the first patient.
"The PARTNERS trial will evaluate the monoclonal antibody MBP134 and the antiviral drug remdesivir, alone and in combination," he added.
Also read: Donald Trump Posts AI Video of Himself Treating Critics for 'Derangement Syndrome'
The study is being coordinated by the DRC's National Institute for Biomedical Research, supported by a coalition of partners including WHO, and conducted in close cooperation with the affected communities.
According to Tedros, patients who enroll in the trial will receive comprehensive supportive care and close follow-up.
"We are also working to ensure they have access to the two drugs should they prove safe and efficacious in the trial."
In addition, the WHO has granted emergency use listing to the first molecular diagnostic test for Bundibugyo virus.
Further, the antiviral drug remdesivir, marketed as Veklury is also expected to start. Remdesivir became widely known during the COVID-19 pandemic and is being evaluated to determine whether it can improve outcomes when combined with the antibody treatment.
As per experts, it could take months, and possibly as many as 1,000 study participants, to determine whether either drug works.
Currently, the study is being offered only at one Ebola treatment center in Congo's Ituri province. The region has been heavily affected by violence, including attacks on healthcare workers responding to a virus spread through contact with infected patients' bodily fluids. Officials plan to expand the trial to other locations once it is safe to do so.
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Tedros said that despite the progress, significant challenges remain, including mistrust and violence.
This week, an Ebola treatment center in Ituri province was attacked, resulting in the deaths of two people. The center was set on fire, and patients fled.
Such acts not only endanger patients and health workers but also impede efforts to stop transmission and save lives.
He added that the complexity of the outbreak requires close coordination across the United Nations system.
Ebola is a severe and often fatal viral hemorrhagic fever first identified in 1976. Since then, more than 30 outbreaks have been recorded, primarily in Central and West Africa.
Common Symptoms of Ebola
Credit: Trump/Truth Social
Amid increasing conversations about Donald Trump suffering from dementia, the US President posted an AI-generated video of himself as a doctor diagnosing celebrities with what he calls "Trump Derangement Syndrome (TDS)."
The clip features AI recreations of Hollywood actors and celebrities, including Whoopi Goldberg, Robert De Niro, Julia Roberts and Rosie O'Donnell, all of whom have previously criticized Trump.
"Have you or someone you know been diagnosed with TDS?" the AI Trump asks at the start of the clip posted on Truth Social.
Calling the "symptoms relentless," the 80-year-old President said that "fortunately, I'm Doctor Trump, and I have a treatment plan," The Independent reported.
The AI-generated Trump then invited viewers to hear from some of his "patients."
"I couldn't eat, I couldn't sleep, constantly angry…" the fake De Niro said. "I made everyone miserable around me."
"I feel like I've aged 20 years in the last two years," added the AI version of Roberts, claiming that she was starting to "worry about her future."
The fake O'Donnell claimed that she had been "suffering for over a decade," while the AI Goldberg said she believed she was a "lost cause."
Other stars spoofed in the 90-second clip include actors Edward Norton and John Leguizamo, both of whom have criticized the president.
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At the end of the video, "Doctor Trump" revealed his "treatment" plan: "Turn off fake news."
He further instructed the AI patients to: "Say your prayers and, if you ever feel anxious, just have a Diet Coke like me and you're gonna see a remarkable difference in your life."
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Trump has often labeled his detractors as having Trump Derangement Syndrome, even claiming in the Oval Office that he had heard it "actually is a disease."
The term is an adaptation of "Bush Derangement Syndrome," which was coined by columnist Charles Krauthammer in 2003.
Krauthammer described the term as "the acute onset of paranoia in otherwise normal people in reaction to the policies, the presidency—nay—the very existence of George W. Bush."
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Trump, who became the oldest US president in history after turning 80 this year, has faced growing public scrutiny over his health.
Recent public appearances have prompted speculation after observers noted swollen ankles, bruising on his hands, verbal slips and occasional episodes in which he appeared drowsy during meetings and international summits.
Some physicians have also publicly expressed concerns about the president's physical and cognitive health, although none have diagnosed him with dementia.
But Trump has repeatedly rejected allegations of cognitive decline or other serious health issues. His most recent annual physical examination also concluded him to be "in excellent health."
The White House also maintains that: "President Trump is the sharpest and most accessible President in American history who is working nonstop to solve problems and deliver on his promises."
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