Study Says Combined Drugs Can Shrink Tumour By 60 Percent In Bowel Cancer

Updated Jul 25, 2024 | 06:09 PM IST

SummaryA new study has found that combining the use of botanciiimab and balstilumab can reduce tumours caused by bowel cancer by 60%, marking the first time a durable response to immunotherapy has been reported in patients suffering from this condition.
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A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.

What Are The Drugs Involved

The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.

The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.

These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.

What Could This Mean For Bowel Cancer Treatment In The Future

The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.

All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.

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DR Congo Ebola Outbreak Becomes World’s Second Largest As Death Toll Surpasses 1,500

Updated Aug 2, 2026 | 09:00 PM IST

SummaryCongo is currently in the midst of the second largest Ebola epidemic in the history of outbreaks. With its number of cases past 3,500, its death has surpassed 1,500.
DR Congo Ebola Outbreak Becomes World’s Second Largest As Death Toll Surpasses 1,500

Credit: AI

The Democratic Republic of the Congo’s (DRC) Ebola outbreak has become the second-largest Ebola epidemic ever recorded, overtaking the country’s devastating 2018-2020 outbreak.

The current epidemic has also underscored the growing global concern over the rapid spread of the deadly disease.

Second-Largest Ebola Outbreak In DR Congo

According to the latest official figures released by the DRC health authorities and the European Centre for Disease Prevention and Control (ECDC), the country has reported 3,442 confirmed Ebola cases and 1,521 deaths as of July 29, 2026.

However, more recent updates indicate the outbreak has continued to worsen rapidly, with 3,532 confirmed cases and 1,556 deaths reported by July 31, 2026.

The only Ebola outbreak larger than the current epidemic remains the 2014-2016 West Africa outbreak, which infected more than 28,000 people and resulted in the deaths of over 11,300 lives.

Also read: Milestone In Kala-Azar Treatment: WHO Updates Treatment Guidelines, Recommends Shorter & Safer Regimens

Ebola Outbreak Caused By Rare Bundibugyo Virus

Unlike many previous Ebola outbreaks caused by the Zaire ebolavirus, the ongoing epidemic is caused by the Bundibugyo virus, a rarer species of Ebola virus for which there is currently no approved vaccine or licensed treatment.

The World Health Organization (WHO) said the outbreak remains active with heightened community transmission, particularly in eastern DRC, where insecurity, mistrust, population displacement and limited healthcare access continue to hamper outbreak containment efforts.

WHO Warns

In its latest Disease Outbreak News update, WHO said, “The outbreak remains active, with sustained transmission.”

The UN health agency noted that inside conflict, population displacement, community mistrust and restricted access to affected areas continue to affect contact tracing, surveillance, and containment and treatment activities.

WHO has also stressed that although the global risk remains low, the regional risk is high because of frequent cross-border movement between the DRC and neighbouring countries.

A major challenge in controlling the epidemic is the absence of a licensed vaccine or targeted therapy against the Bundibugyo virus.

According to WHO, while the Ebola vaccine used against the Zaire strain has shown limited experimental cross-protection in animal studies, there is currently inadequate evidence to recommend its use against Bundibugyo virus disease.

Also read: Uganda Declared Ebola-Free As Congo Outbreak Grows To 3,262 Cases, 1,437 Deaths

First Volunteer Receives Experimental Bundibugyo Vaccine

Amid the worsening outbreak, researchers have reached an important milestone in Ebola vaccine development.

The first volunteer has received an experimental vaccine targeting the Bundibugyo strain of Ebola, marking the world's first Phase I clinical trial for this virus, according to the University of Oxford.

The vaccine, ChAdOx1 BDBV, developed in collaboration with Serum Institute of India (SII), is designed specifically to protect against the Bundibugyo strain of Ebola.

It uses the same viral vector platform that powered the Oxford-AstraZeneca COVID-19 vaccine.

The vaccine uses a genetically modified chimpanzee adenovirus (ChAdOx1)—a harmless virus that normally causes the common cold in chimpanzees—as a delivery vehicle.

"We welcome the start of the phase 1 clinical trial of an investigational vaccine against Ebola Bundibugyo virus disease—an important step to assess the safety and immune responses generated by the vaccine," said WHO Director-General Tedros Adhanom Ghebreyesus on X.

Health authorities, supported by WHO, Africa CDC and international partners, continue to strengthen surveillance, laboratory testing, infection prevention, community engagement and patient care.

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After ‘Ozempic Face’, Experts Warn of ‘Ozempic Hair’; Why Are GLP-1 Users Facing Hair Loss?

Updated Aug 2, 2026 | 07:00 PM IST

SummaryGLP-1 users have been facing excessive hair loss three to four months after starting the drugs. Experts talk about the emerging trend, focusing on how to prevent it.
After ‘Ozempic Face’, Experts Warn of ‘Ozempic Hair’; Why Are GLP-1 Users Facing Hair Loss?

Credit: AI

The growing popularity of GLP-1 weight loss drugs like Ozempic, Wegovy and Mounjaro has brought another side effect into focus.

After the widely discussed 'Ozempic Face,' dermatologists are now warning about 'Ozempic Hair,' a term used to describe excessive hair shedding that can occur after rapid and weight loss.

Experts say the condition is not caused by the medication directly damaging hair follicles. Instead, it is largely linked to rapid weight loss, nutritional deficiencies, and the body's metabolic response to sudden calorie restriction.

Why Are GLP-1 Users Facing Excessive Hair Loss?

According to Dr. Gaurav Garg, Senior Dermatologist, Hair Transplant Surgeon, Dermato-Surgeon and Medical Director at Dermalife Skin and Hair Clinic, New Delhi, cases have become increasingly common in dermatology clinics.

"We are seeing a significant rise in patients complaining of excessive hair shedding after taking GLP-1 weight loss medications. Around 40% of the weight loss drug users visiting our clinics are experiencing mild to significant hair loss, with many noticing hair falling out in large clumps while washing or combing. In most cases, the medication itself is not directly damaging the hair. The problem is rapid weight loss, nutritional deficiencies and the metabolic shock experienced by the body," Dr. Garg said.

He added that the increasing use of these medications without proper medical supervision is further contributing to the problem.

"Ozempic isn't the enemy of your hair; malnutrition and metabolic shock are. By ensuring gradual weight loss and proper nutritional support under expert guidance, many of these problems can be prevented," he said.

Also read: UK Woman Spends £4,000 On Wegovy, Mounjaro, But Loses Less Than 14 Pounds In 15 Months

What Is 'Ozempic Hair'?

'Ozempic Hair' is not a medical diagnosis but a popular term for telogen effluvium, a temporary phase of hair loss due to stress. Rapid weight loss acts as a physical stressor, causing a larger number of hair follicles to enter the resting phase prematurely.

Hair shedding usually becomes noticeable three to four months after a user starts taking GLP-1 drugs. Reduced appetite during treatment may also result in deficiencies of all the nutrients that are important for hair growth. For example, protein, iron, zinc and biotin.

Also read: GLP-1 Microdosing: People Are Experimenting With Weight Loss Drugs & What Do Experts Have To Say About It?

Experts Warn Against Self-Medication

Dr. Garg cautioned that weight loss injections are increasingly being used for cosmetic purposes rather than for legitimate medical conditions.

"One of the biggest concerns today is that these weight loss injections are increasingly being viewed as quick-fix cosmetic solutions rather than prescription medicines meant for specific medical conditions. Many people begin taking them after watching social media content or on the advice of friends, without understanding the nutritional consequences. Hair shedding in most cases is temporary, but prevention is always better than treatment. These medications should never be used casually or without expert supervision," he said.

He stressed that people undergoing medical weight loss should receive appropriate dietary counselling, consume adequate protein, and undergo regular monitoring to reduce nutritional complications.

Echoing these concerns, Dr. Ramanjeet Singh, Director, Department of Dermatology, Medanta Hospital, said the trend reflects the risks of unsupervised use of GLP-1 medications.

"The emerging trend of 'Ozempic Hair' highlights the risks associated not only with rapid weight loss but also with the indiscriminate use of these medications without proper medical evaluation. We are increasingly seeing individuals obtaining weight loss drugs without specialist consultation or using them beyond recommended doses in pursuit of faster results. Hair shedding in such cases usually represents telogen effluvium triggered by rapid metabolic changes and nutritional deficiencies rather than permanent damage to the hair follicles," Dr. Singh said.

He added that the condition is generally reversible with timely intervention, balanced nutrition and medically supervised weight management.

Dermatologists advise people considering prescription weight loss medications to undergo a medical evaluation before starting treatment.

Maintaining adequate protein intake, avoiding crash diets, correcting iron and vitamin deficiencies where necessary, and seeking early dermatological care if excessive hair shedding develops may help reduce the severity and duration of hair loss.

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'Nasha Mukt Yuva' Campaign Launched: PM Modi Kicks Off 100-Week Nationwide Drive Against Substance Abuse

Updated Aug 2, 2026 | 03:00 PM IST

SummaryPM Narendra Modi recently launched Nasha Mukt Yuva for Viksit Bharat Sankalp Abhiyan, a 100-week campaign aimed at curbing substance abuse among younger population.
'Nasha Mukt Yuva' Campaign Launched: PM Modi Kicks Off 100-Week Nationwide Drive Against Substance Abuse

Credit: AI

On Sunday, Prime Minister Narendra Modi launched the 'Nasha Mukt Yuva for Viksit Bharat Sankalp Abhiyan'.

It is a nationwide 100-week campaign aimed at discouraging young people from substance abuse through community participation, awareness activities and various other initiatives.

About Nasha Mukt Yuva for Viksit Bharat Sankalp Abhiyan

Launched via video conferencing, the campaign seeks to transform young Indians into ambassadors of a drug-free society. The campaign has weekly events scheduled every Sunday across the country.

More than 10,000 locations joined the launch virtually, bringing together MY Bharat volunteers, National Service Scheme (NSS) members, schools, colleges, universities, NGOs, industry associations and over 125 spiritual organisations.

Addressing the gathering, Prime Minister Modi said that a healthy and drug-free youth population is essential for building a developed India (Viksit Bharat).

The Prime Minister said, "A drug-free youth is the greatest strength of Viksit Bharat. This campaign should reach every village, every town and every city through Jan Bhagidari."

He also said that substance abuse not only destroys individual lives and families but can also become a tool used by hostile enemy forces to weaken the country's future.

He also said, "Drugs destroy families, careers and the future of young people. Parents, teachers and society must come together to protect our youth from this menace." A healthy youth is the greatest strength of a Viksit Bharat. If our young generation stays fit physically and mentally, no force can stop India's progress."

Also read: Healthcare In India No Longer A Privilege, Becoming A Right: PM Modi

What Will Happen Over The Next 100 Weeks?

Unlike one-day awareness campaigns, the initiative is designed as a long-term public movement. Every Sunday, communities across India will organise activities such as:

  • Walkathons and cycling events
  • Sports competitions
  • Meditation and yoga sessions
  • Nukkad nataks and cultural programmes
  • Art and poster competitions
  • Community discussions and awareness drives

The government hopes the sustained weekly engagement will encourage behavioural change, especially among adolescents and young adults, while strengthening grassroots participation.

Also read: PM Modi Pledges 7.5 million For Cancer Moonshot Initiative: What Is It

A Broad Anti-Drug Strategy

The campaign builds on a series of youth-focused initiatives launched this year under the 'Nasha Mukt Yuva for Viksit Bharat' umbrella, including the National Nasha Mukti Quiz, awareness programmes in educational institutions, the Nasha Mukti Anthem initiative and youth conclaves across the country.

These efforts are part of the broader Nasha Mukt Bharat Abhiyaan, which has been expanded nationwide to curb drug problem through prevention, awareness and community engagement.

Officials say the latest campaign aims to create a society-level movement by bringing together educational institutions, youth organisations, society groups, corporate bodies and spiritual organisations on a common platform.

With one crore youth also taking the Nasha Mukti pledge during the launch, the government hopes the campaign will evolve into one of India's largest community-led efforts to prevent substance abuse.

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