A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.

What Are The Drugs Involved

The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.

The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.

These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.

What Could This Mean For Bowel Cancer Treatment In The Future

The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.

All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.

Malaria Alert in Germany: Frankfurt Airport Worker Dies After Suspected ‘Mosquito Arrives on Plane’; 5 Infected

In an unusual case, an employee at Germany’s Frankfurt Airport has died from malaria, while five others have contracted the potentially serious infection after mosquitoes suspected of arriving on an aircraft were found at the airport.

The airport operator, Fraport, confirmed the employee’s death and said the five other infected people are receiving medical treatment.

Authorities have installed mosquito traps at the airport. Captured mosquitoes will be analysed in laboratories to determine their species and, where possible, establish their origin.

Fraport said its focus is now on information and prevention. Employees have been advised to seek medical attention if they develop malaria-like symptoms and to inform doctors that they work at the airport.

“Sadly, we must confirm that one employee has died as a result of the infection,” a Fraport spokesperson told the BBC.

The company said it had provided information to employees and urged them to consult a doctor if they develop symptoms.

What Happened?

According to Germany's Robert Koch Institute (RKI), four airport employees developed malaria between 4 and 6 July. The institute said mosquitoes were brought to the airport by aircraft from a malaria-endemic region in July.

Malaria transmission within Germany is extremely rare. The RKI says malaria cases in the country almost exclusively occur among people who have travelled to malaria-endemic areas.

The absence of a travel history can make diagnosis more difficult. A delayed diagnosis can increase the risk of severe disease.

The RKI also noted that the last airport-associated malaria case in Germany occurred at Frankfurt Airport in 2023.

What Is Malaria?

Malaria is a potentially life-threatening disease caused by Plasmodium parasites, which are transmitted to humans through the bites of infected female Anopheles mosquitoes.

Common symptoms include fever, chills and headache. More severe malaria can cause confusion, seizures, difficulty breathing and other life-threatening complications.

Symptoms generally begin around 10–15 days after the bite of an infected mosquito, although the timing can vary.

People at increased risk of severe malaria include young children, pregnant women, travellers without immunity and people with HIV/AIDS.

Malaria is not normally transmitted directly from person to person. However, transmission can occur through infected blood, including in rare circumstances through blood transfusion or contaminated needles.

Global Malaria Burden

According to the World Health Organization's World Malaria Report 2025, an estimated 282 million malaria cases and 610,000 deaths occurred worldwide in 2024 across 80 malaria-endemic countries.

The WHO African Region accounted for approximately 94% of global malaria cases and 95% of malaria deaths in 2024.

WHO estimates that malaria-prevention tools, including recommended vaccines and other interventions, helped avert approximately 170 million cases and 1 million deaths in 2024.

The report noted that WHO approved the world’s first malaria vaccines in 2021, and 24 countries have now added them to their regular immunisation schedules.

Despite the setbacks, there have been encouraging developments. So far, 47 countries and one territory have received malaria-free certification from WHO. Cabo Verde and Egypt were declared malaria-free in 2024, followed by Georgia, Suriname, and Timor-Leste in 2025.

COVID-19 is rising across the US again. Doctors have been reporting an increase in patients testing positive through the summer. But some physicians are noticing a change in how the illness is presenting.

Reports have emerged stating that COVID is resurfacing with new symptoms including nausea, vomiting and diarrhoea.

The CDC's latest respiratory illness data, updated August 21, shows that national and regional COVID-19 activity is increasing, although overall acute respiratory illness causing people to seek healthcare remains very low. COVID-19-related visits to the emergency room are also increasing.

Recent reports from doctors in Georgia describe patients arriving with gastrointestinal symptoms alongside, or sometimes instead of, the more familiar respiratory symptoms.

Nausea, Vomiting And Diarrhoea Are Uncommon COVID Symptoms

Although these symptoms may seem unusual compared with the classic COVID presentation, nausea, vomiting and diarrhoea are not new symptoms of COVID-19.

The CDC has included nausea, vomiting and diarrhoea among the possible symptoms of COVID-19 for years. What appears to be attracting attention now is that some doctors are seeing more patients presenting with these gastrointestinal symptoms during the current summer rise.

Dr James Black, medical director of emergency services at Phoebe Putney Memorial Hospital in Albany, Georgia, said doctors are still seeing fever, cough and upper-respiratory symptoms, but added, “A lot of people are coming in with gastrointestinal symptoms - nausea, vomiting, diarrhea, sometimes to the point of mild dehydration.”

Also read: Exclusive With Leading Pulmonologist: When Should You Worry About H1N1 Symptoms?

Why COVID Affects The Digestive System?

The digestive system contains ACE2 receptors, which the virus can use to enter cells. Infection and the body's inflammatory response can therefore contribute to symptoms like nausea, vomiting and diarrhoea.

Gastrointestinal symptoms can occur with respiratory symptoms or sometimes before them, which can make COVID harder to distinguish from stomach infections or food poisoning. That is why doctors say testing remains essential, especially when COVID is active in a certain area.

Also read: ‘Scromiting’: Cannabis-Linked Vomiting Cases Rising Again In US, Says CDC Report

What Are The Other Symptoms?

Doctors say people should not focus only on gastrointestinal symptoms. Common COVID symptoms include:

• Fever or chills
• Cough
• Sore throat
• Congestion or runny nose
• Fatigue
• Headache
• Muscle or body aches
• Shortness of breath
• Nausea or vomiting
• Diarrhoea

Also read: US CDC Says COVID ‘Growing’ In Nearly Every State: What You Should Know

When Should You Take A COVID Test?

If nausea, vomiting or diarrhoea occur alongside fever, cough, sore throat, congestion, fatigue or body aches, COVID should be considered, particularly when infections are increasing in the community. Testing can be especially important for people at higher risk of severe disease because antiviral treatment works best when started early.

Dr Gurinder Singh Sidhu, US antiviral medical lead and senior director at Pfizer, said, "People at higher risk should seek medical advice promptly rather than waiting for symptoms to become severe."

Severe vomiting or diarrhoea can also cause dehydration, so people should seek medical care if they cannot keep fluids down, are becoming unusually weak or dizzy, are urinating much less than usual, or develop breathing difficulties.

What if an old plastic bottle could become part of your next snack? Scientists at Southern Illinois University Carbondale have created a process that converts plastic and agricultural waste into ingredients for protein-rich, 3D-printed cookies.

The unusual food, called µBites, is being developed as part of NASA’s project to explore ways to produce food in environments where there are limited resources like long deep-space missions.

The researchers say that the technology could also have applications in disaster-afflicted zones and areas where there are acute food shortages.

Can Plastic Be Turned Into Food?

The process starts with polyethylene terephthalate (PET), the type of plastic commonly used to make water and soft-drink bottles.

Researchers first break down PET, along with discarded corn stalks and leaves, using a process called oxidative hydrothermal dissolution.

It uses water and oxygen at high temperatures and pressures to turn the tough waste materials into smaller molecules that microbes can use.

The researchers then use specially programmed yeast as tiny biological factories. The yeast converts compounds derived from the waste into proteins, fats, acids, vitamins and flavouring molecules.

The resulting mixture is mixed with ingredients like fibre, starch and sweetener before being moulded into cookies using a 3D printer.

Also read: Microplastics Found In Anchovies’ Edible Muscle: What It Means For Brain Health

Researchers Say The Idea Came From Two Global Problems

Associate Professor Lahiru Jayakody, who leads the project, said the team was initially looking for ways to turn plastic waste into more valuable products. “Why not focus on making food? Because plastic is carbon and food is carbon,” Jayakody said.

He added that the researchers are using microbes to solve problems created by humans. He said, “Microbes are very clever. So, we are using their traits to solve the problems we created.”

The approach could possibly tackle two problems simultaneously — plastic pollution and the need for reliable food sources in environments where conventional agriculture is impossible.

Also read: Brazilian Woman Dies After 6 Cosmetic Procedures In 8 Hours: How Can Beauty Treatments Go Wrong?

Could These Cookies Actually Be Safe To Eat?

The researchers say their current data show that the µBites are safe to eat, but they have not yet undergone human taste testing. The research team is awaiting approval before conducting human trials.

Preliminary smell evaluations were promising. Most participants said they would be willing to eat the product in an environment where there is no food source. That distinction matters because turning plastic into food ingredients does not mean people are eating plastic itself.

The PET is chemically broken down first, and microbes then use its carbon-containing components to produce new biological molecules.

Also read: Paris Jackson Undergoes ‘Painful’ ECT for Depression: Can Electroconvulsive Therapy Reduce Suicide Risk?

Why NASA Is Interested In Plastic-Based Food?

Long-duration space missions present a particularly difficult food challenge.

Astronauts cannot realistically carry unlimited supplies of fresh food, while growing enough crops in space requires substantial water, energy and equipment.

A system capable of turning waste materials into food ingredients could therefore help reduce the amount of food and raw materials that need to be transported from Earth.

The researchers envision the technology eventually being useful in submarines, disaster-response situations and other isolated environments, in addition to space exploration.