Study Says Combined Drugs Can Shrink Tumour By 60 Percent In Bowel Cancer

Updated Jul 25, 2024 | 06:09 PM IST

SummaryA new study has found that combining the use of botanciiimab and balstilumab can reduce tumours caused by bowel cancer by 60%, marking the first time a durable response to immunotherapy has been reported in patients suffering from this condition.
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A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.

What Are The Drugs Involved

The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.

The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.

These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.

What Could This Mean For Bowel Cancer Treatment In The Future

The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.

All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.

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US Surgeon General Issues Advisory To Limit Children's Screen Time

Updated May 23, 2026 | 06:00 AM IST

Summary​Health and Human Services Secretary Robert F. Kennedy Jr. said evidence of risks to children’s physical and mental health is “mounting,” even though screens can also provide some benefits.
US Surgeon General Issues Advisory To Limit Children's Screen Time

Credit: iStock

Excessive screen time use is harming sleep, mental health, learning, and development of children, according to a new advisory by the US surgeon general’s office, which urged parents to limit children’s screen time.

Even as President Donald Trump's nominee for surgeon general awaits confirmation, the "Harms of Screen Use" bulletin warns that children and teens are spending more time on their digital devices than on sleep or school, the USA Today reported.

It noted that excessive screen use is linked to heavy or compulsive screen use

  • anxiety,
  • depression,
  • poor academic performance,
  • behavioral problems
  • developmental delays.

Health and Human Services Secretary Robert F. Kennedy Jr. said evidence of risks to children’s physical and mental health is “mounting,” even though screens can also provide some benefits.

The advisory promotes the slogan “Live real life,” encouraging children and families to replace excessive screen use with in-person activities and healthier routines.

Alongside the report, the officials also released a toolkit recommending steps for parents, schools, healthcare providers, and policymakers to help reduce screen dependence and encourage safer technology habits among young people.

The advisory also links excessive and "compulsive" screen use to

  • poor sleep and school performance,
  • mental health issues like anxiety and depression,
  • behavioral and social issues, substance abuse, and developmental disruptions.

The report aligns with recent studies, which show how too much screen time affects developing minds.

Recent findings from the All India Institute of Medical Sciences, Delhi, suggest that early digital exposure to children before the age of one increases the baby's risk of autism.

The findings led by the Department of Pediatric Neurology showed that infants exposed to high levels of digital media at around one year of age are significantly more likely to display autistic signs by the time they reach age three.

India has also issued pediatric and education guidelines advising parents to limit screen exposure for young children, though there is no nationwide ban. States like Karnataka and Andhra Pradesh have also taken up action against social media use and screen time.

Countries banning screen time

While countries are not fully “banning” screen time, several of them have introduced restrictions, guidelines, or proposed laws aimed at reducing children’s screen time, especially around smartphones and social media in schools.

  • France banned smartphones in primary and middle schools in 2018 and has tested stricter “digital pause” policies for students under 15.
  • China has some of the world’s toughest rules, including limits on video game play for minors, restrictions on nighttime gaming, and proposed limits on smartphone use for children.
  • South Korea introduced laws targeting gaming addiction among minors, including past shutdown rules that blocked late-night gaming for children.
  • Netherlands and Finland have encouraged schools to restrict phones in classrooms to improve concentration and learning.
  • Australia has debated stronger social media age restrictions, and several states have tightened school phone bans.
  • United Kingdom schools widely enforce smartphone bans, while lawmakers continue discussing stricter online safety rules for children.
  • Sweden has pushed for reduced screen exposure in early childhood education, emphasizing printed books and traditional learning methods.

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India Digitalizes Health Records Of 100 Crore People Under Ayushman Bharat

Updated May 22, 2026 | 10:00 PM IST

SummaryUttar Pradesh emerged as the leading contributor with over 15.03 crore ABHA-linked health records, followed by Andhra Pradesh with over 11.95 crore linked records. Bihar, Rajasthan, and Gujarat also linked over 7.37 crore, 6.32 crore, and 4.77 crore health records, respectively.
India Digitalizes Health Records Of 100 Crore People Under Ayushman Bharat

Credit: AI generated image

India has successfully linked the health records of more than 100 crore people with Ayushman Bharat Health Accounts (ABHA) under the Ayushman Bharat Digital Mission (ABDM), the Ministry of Health and Family Welfare said today.

Implemented by the National Health Authority, the milestone marks a major step towards building an integrated, citizen-centric, and interoperable digital healthcare ecosystem in the country.

“The linking of over 100 crore health records with ABHA is an important milestone in the journey of Ayushman Bharat Digital Mission. ABHA-linked health records empower citizens with secure and consent-based access to their health information and support continuity of care across the healthcare ecosystem,” said Dr. Sunil Kumar Barnwal, CEO, NHA.

The Growing Adoption Of ABDM

According to the Ministry, more than 450 public and private health technology solutions have integrated with the ABDM ecosystem, enabling digitisation and seamless exchange of health records across healthcare facilities.

The ministry said ABDM doubled the number of linked health records from 50 crore in February 2025 to over 100 crore in just 15 months.

Nearly 10 crore health records are now being linked every two to three months. From fewer than 1,000 linked records during its initial phase to over 100 crore today, ABDM has evolved into one of the world’s largest digital health ecosystems.

Uttar Pradesh emerged as the leading contributor with over 15.03 crore ABHA-linked health records, followed by Andhra Pradesh with over 11.95 crore linked records.

Bihar, Rajasthan, and Gujarat also recorded major progress by linking over 7.37 crore, 6.32 crore, and 4.77 crore health records, respectively.

Also read: Preeclampsia Is Preventable & Treatable. Yet It’s India’s 3rd Leading Cause Of Maternal Deaths, Says AIIMS doctor

Programs Contributing To The Milestone

Among the major government programs and digital platforms contributing to the milestone are:

  • Non-Communicable Disease Program
  • CoWIN
  • Pradhan Mantri Jan Arogya Yojana
  • Uttar Pradesh government’s eKavach platform
  • Andhra Pradesh health programs
  • Reproductive and Child Health (RCH) program
  • eHospital by National Informatics Centre
  • eSushrut by Centre for Development of Advanced Computing
  • Gujarat government’s TeCHO platform
  • Rajasthan government’s iHMS platform

Private health technology partners and ABDM-enabled digital solutions have also contributed significantly towards the creation and linkage of ABHA-linked health records.

What Is ABHA?

ABHA is a unique digital health identity that allows citizens to securely link and access their health records across hospitals, clinics, laboratories, and healthcare providers.

Through ABDM’s consent-based health information exchange mechanism, citizens can digitally share their medical records with registered healthcare providers while maintaining the privacy and security of personal health information.

“ABDM is designed to place citizens at the center of the digital health ecosystem. With consent-based sharing of health records, individuals can access their medical information whenever required and share relevant records with healthcare providers digitally. This will help make healthcare delivery more accessible, efficient, and patient-centric,” Barnwal said.

Key Digital Building Blocks Of ABDM

The Ayushman Bharat Digital Mission is creating the digital public infrastructure required for an interoperable healthcare ecosystem through key digital building blocks such as:

  • Ayushman Bharat Health Account (ABHA)
  • Healthcare Professionals Registry (HPR)
  • Health Facility Registry (HFR)
  • Health Information Exchange and Consent Manager (HIE-CM)
  • Unified Health Interface (UHI)
  • National Health Claims Exchange (NHCX)

With over 100 crore health records now linked with ABHA, ABDM has marked another milestone towards creating longitudinal digital health records for citizens and enabling a more connected, paperless, efficient, and patient-centric healthcare ecosystem in the country.

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Ebola Outbreak: Kerala To Keep Visitors From Affected Countries Under Surveillance For 21 Days

Updated May 22, 2026 | 09:00 PM IST

SummaryThe state government of Kerala has taken several steps to prevent an Ebola outbreak in the state. Among the new guidelines, the state has mentioned a monitoring period of up to 21 days for those travelers who came from the nations affected by Ebola.
Ebola Outbreak: Kerala To Keep Visitors From Affected Countries Under Surveillance For 21 Days

Credit: Canva

Amid the rising cases of Ebola virus infection in nations like the Democratic Republic of the Congo, Uganda, and South Sudan, the whole world has gone to an alert mode. The state government of Kerala has declared that it will keep the visitors from the countries flagged by the World Health Organization (WHO) under mandatory health surveillance for up to 21 days after arrival.

The government of India has already issued an advisory on this important issue. In accordance with the direction, the state government of Kerala has also taken some strict steps to protect the general public from this infectious virus. On Thursday, at the meeting of the State Rapid Response Team, Health Minister K. Muraleedharan said the measure was being adopted as an additional precaution.

The Union Health Ministry has also propagated a stricter stance on preventing the virus outbreak in the country. The ministry emphasizes its stance by issuing orders to strictly follow the special health guidelines.

As per the new norms, the travelers from Ebola-affected nations are asked to report to the health authorities at the airport if they feel symptoms commonly associated with Ebola, like fever, headache, fatigue, vomiting, diarrhoea, muscle pain, sore throat, or bleeding. Those who had any contact with confirmed or suspected Ebola patients have also been informed by the health authorities.

The state government has made screening of passengers stricter in the international airports and seaports.

In addition to that, the authorities have also searched isolation wards and intensive care facilities throughout the state to find those who require treatment or observation.

The health minister of the state ordered ample training of healthcare personnel in infection prevention and control. There is also emphasis on the use of PPE kits, proper treatment protocols, and critical care management.

What is Ebola?

Ebola is a severe and, in most cases, deadly disease caused by viruses predominantly found in Africa. The spread of the disease happens through contact with infected body fluids.

Some symptoms can indicate a possible infection. This includes fever, weakness, headache, muscle pain, vomiting, diarrhea, sore throat, and unexplained bleeding. This eventually leads to severe complications like bleeding, organ failure, and death. The hosts of the virus are animals like bats, primates, and antelopes.

WHO Says Vaccine Could Take Months

Meanwhile, Tedros Adhanom Ghebreyesus, WHO Chief said he was “deeply concerned about the scale and speed of the epidemic”. He noted that the numbers are expected to rise given the time taken to detect the virus.

The WHO says it could take up to nine months before a vaccine against this particular species of Ebola is ready.

Two possible "candidate vaccines" against the Bundibugyo species are being developed, but neither has gone through clinical trials yet, WHO advisor Dr. Vasee Moorthy said, according to the BBC.

Speaking to journalists in Geneva, Tedros said 51 cases have been confirmed in the Democratic Republic of Congo — where the first case was reported — and two in neighboring Uganda.

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