A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.
What Are The Drugs Involved
The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.
The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.
These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.
What Could This Mean For Bowel Cancer Treatment In The Future
The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.
All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.
Credit: X
Two people have suffered burn injuries in Mumbai after a cluster of gas-filled balloons exploded and turned into a ball of fire inside a residential building’s lift earlier this week.
The incident occured at Anmol Towers, a residential building opposite a petrol pump in Mumbai's Goregaon West and police have registered a case against the balloon vendor, according to NDTV.
CCTV footage shows a woman entering the lift with a small trolley, followed by a man carrying several balloons packed in a large bag. Moments later, the balloons mysteriously caught fire, leading to the blast inside the elevator.
Despite flames briefly covering the CCTV camera, the woman and two men were seen running out of the elevator seconds later. In the end, the clip shows the elevator doors shutting as flames erupt at the centre of the lift.
It was unclear what type of gas was used to inflate the balloons. However, while many consumers assume decorative balloons are filled with helium, a non-combustible gas, authorities and safety experts suggest that it is highly possible that hydrogen was used instead.
Mumbai police have urged the public to exercise caution and warned balloon sellers against using flammable gases, particularly in residential buildings and enclosed areas.
Hydrogen has a very wide range of flammability in air (4-75 percent by volume) and requires very low energy to ignite. It often causes explosions rather than just fires, especially in confined spaces.
In high concentrations in enclosed areas, hydrogen acts as a simple asphyxiant by displacing oxygen, which can lead to dizziness, unconsciousness, or death. Additionally, hydrogen fires burn with a nearly invisible, pale blue flame, making them almost impossible to detect with the naked eye during daylight.
Moreover, hydrogen gas also burns faster than most conventional fuels, increasing the risk of deflagration (subsonic) or detonation (supersonic).
On the other hand, as a noble gas, helium has a completely filled outer shell of electrons, meaning it does not react with other elements or catch fire in the presence of oxygen and heat.
Along with this, unlike hydrogen, which is also lighter than air but highly explosive, helium will not ignite even if exposed directly to a flame or spark and it can can act as a buffer and actually suppress flames by displacing oxygen in the immediate area.
For minor burns, immediately run cool (not cold) water over the area for 10–20 minutes, remove jewelery or tight clothing near the injured area and cover with a sterile bandage. A minor burn might need emergency care if it affects the eyes, mouth, hands or genitals.
However, for serious and large burns, protect the burned person from further harm and ensure that they are breathing. Loosely cover the area with gauze or a clean cloth and raise the burned area above heart level, if possible.
As you call emergency services, watch for symptoms of shock which include cool, clammy skin, weak pulse and shallow breathing.
Seek immediate care for burns, which:
Globally, about 10 million people experience burns and about 180,000 die from them each year.
A woman with no travel history has died from Nipah virus in Bangladesh, the World Health Organization has confirmed.
The patient, aged between 40 and 50, developed a fever and headache-like symptoms consistent with the virus, followed by hypersalivation, disorientation and convulsion on 21 January.
The case was reported in the northern Naogaon district, Sharmin Sultana, senior scientific officer at the Institute of Epidemiology, Disease Control and Research, later said.
She died on January 28 and was confirmed to be infected with the virus the day after. Although she had no travel history, she regularly consumed raw date palm sap, reports suggest.
The WHO said all 35 people who had contact with the now-deceased patient were being monitored and have tested negative for the virus. No new cases had been detected to date.
Since its emergence in 2001, Bangldesh has reported cases of Nipah virus in humans every year. In 2025, four laboratory-confirmed fatal cases were reported in the country.
The Nipah virus outbreak began in West Bengal, India in January with two hospital nurses at AIIMS, Kolkata, testing positive for the infection and being quarantined, prompting widespread testing. Soon after, five cases, including a doctor and a staff member, were confirmed and over 100 people were quarantined.
However, one of the nurses, a 25-year-old unidentified man has now made a recovery and revealed his experience with the virus, claiming that despite irritation in the throat and uncertainty about what lay ahead, he had faith in his doctors and fellow nurses.
In an interview with the Metro, he said: “After I was taken off ventilation and regained consciousness, I came to know that I have Nipah. I still had the tube in my mouth, and there was irritation. Despite the irritation and my fear, I had faith in the doctors and nurses.
“I have suffered and I know the symptoms. I will tell people when they should get checked for the Nipah virus. I want to raise awareness about the virus and its symptoms.
“I am not sure how I came in contact with the deadly virus. Maybe it was while treating a patient. But I will continue to work as a nurse. I am waiting to rejoin the hospital,” he added.
The unidentified healthcare professional remains very weak physically and is undergoing physiotherapy to regain his strength. “I was bedridden for over a month. I am still very weak and have an unstable gait. So, I am undergoing physiotherapy,” he said.
The other nurse, a woman, remains in a coma but has been taken off ventilation support, a hospital official confirmed this week.
According to WHO, Nipah virus is a zoonotic illness which means it is mostly transmitted from animals to humans through bats. However, it can also spread through fruits that have been contaminated by the saliva, urine or droppings of infected bats. Human-to-human transmission can also occur through close contact with an infected person or their bodily fluids.
The illness has a 75 percent fatality rate, and there are no vaccines to protect the public.
The virus was first identified in 1998 during an outbreak among pig farmers in Malaysia and soon made its way to India and Bangladesh in 2001, with cases often involving family members or caregivers tending to the infected patient.
READ MORE: Nipah vs Bird Flu in India: Which Virus Poses A Greater Threat To Humans?
Although the Nipah virus has caused only a few known outbreaks in Asia, it infects a wide range of animals and causes severe disease and death in people. Some of its common symptoms include:
Samples collected from the patient’s home and workplaces, including pets and partially eaten fruits dropped by bats, all tested negative for the virus, and the exact source of the infection could not be identified.
Credits: Canva
Wet Wipes Waring: 59 people have fallen ill, with one dead, after using non-alcoholic, non-sterile, infected wet wipes in UK. The UK Health Security Agency (UKHSA) and Medicines and Healthcare products Regulatory Agency (MHRA) issued a warning, and said that there is still "an ongoing risk of infection associated with their use". The bacteria that is causing this infection is burkholderia stabilis or B. stabilis.

The UKHSA also in its warning included names of four different wet wipes and asked people to avoid using them.
The Pharmaceutical Journal noted that the UKHSA and MHRA published a joint statement that warned people that they should not use non-sterile, non-alcoholic wipes in their homes and first-aid kits.
After an outbreak investigation conducted by MHRA in 2025, four products were identified to be contaminated with Burkholderia stabilis. “There have been 59 confirmed cases of Burkholderia stabilis associated with some non-sterile alcohol-free wipe products — identified in an outbreak in the United Kingdom from January 2018 to 3 February 2026,” the statement said.
“A small number of cases continue to be detected. These have included some serious infections which have required hospital treatment and one death has been attributed to Burkholderia stabilis infection.”
UKHSA and MHRA is telling people to look out for wipes marked 'sterile' to be used on wounds or broken skin.
UKHSA on its official website notes: 'Burkholderia are a type of bacteria found naturally in the environment, including in soil and water. Burkholderia stabilis is one species within this group. While many people never encounter problems with this type of bacteria, it can cause serious infections in certain circumstances, particularly among vulnerable individuals.'
Read: Does Bigger Penis Help You Ski Better? Why Olympians Are Injecting Hyaluronic Acid - Explained
The UKHSA notes: "The risk of acquiring infection is generally very low. Infections can occur through contact with contaminated products on broken or damaged skin, or through introduction of bacteria through medical devices such as intravenous lines."
© 2024 Bennett, Coleman & Company Limited