A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.

What Are The Drugs Involved

The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.

The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.

These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.

What Could This Mean For Bowel Cancer Treatment In The Future

The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.

All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.

Police in Guinea-Bissau raided the Bandim Health Project on Monday, October 19, and seized a batch of hepatitis B vaccines intended for a controversial trial involving 14,000 newborns, according to an official statement.

The project’s Danish researchers, Peter Aaby and Christine Stabell Benn, are at the center of the dispute. The study received $1.6 million from the US Centers for Disease Control and Prevention (CDC), matched by the Pershing Square Foundation and the Bluebell Foundation, bringing total funding to $3.2 million. US Health and Human Services Secretary Robert F. Kennedy Jr. has praised the researchers’ work.

The police search took place on Monday, involving “investigative procedures aimed at clarifying the circumstances related to the said batch of vaccines”, according to the social media post, which was translated from Portuguese. The announcement noted that seizing the immunizations did not point to “irregularities in the quality, safety, or effectiveness of the vaccines”, The Guardian reported.

Why Is the Hepatitis B Vaccine Trial Controversial?

The proposed trial would randomly divide 14,000 newborns into two groups: one would receive the hepatitis B vaccine at birth, while the other would receive it six weeks later.

The WHO recommends hepatitis B vaccination within 24 hours of birth to prevent mother-to-child transmission.

Why Is Delaying Vaccination a Concern?

Also read: Hepatitis B Infections Could Rise 83% If US Changes Newborn Vaccine Policy: Study

Hepatitis B is highly endemic in Guinea-Bissau, affecting more than 12% of adults. Infants infected at birth have about a 90% chance of developing chronic infection, which can lead to cirrhosis, liver failure and liver cancer.

Stig Børsen Hansen, a member of the University of Southern Denmark’s ethics committee, resigned after the committee narrowly approved the updated protocol. He warned that the trial would expose some newborns to potentially serious infections by delaying vaccination.

What Is the Study Investigating?

Rather than testing the vaccine’s established efficacy, the study aims to investigate the proposed “non-specific effects” of vaccines — potential health effects beyond protection against targeted infections.

Critics argue that delaying a recommended birth dose to investigate these hypotheses exposes newborns to avoidable risks. Former Guinea-Bissau Health Minister Magda Robalo and other critics have also raised concerns about conducting such research in a vulnerable population.

What Have Authorities Said?

The Bandim Health Project published an approval letter from Guinea-Bissau’s national ethics committee, dated July 14. A Danish research ethics committee also approved the study earlier this month.

However, transitional government Health Minister Quinhin Nantote disputed reports that the trial would proceed, telling The Guardian: “This is not even remotely true.”

WHO spokesperson Tarik Jašarević said a study denying newborns the vaccine would be “unethical” and expose them to “serious and potentially irreversible harm.” The WHO is advising Guinea-Bissau’s Ministry of Health on introducing the vaccine and assessing the study’s potential impact.

Why Is RFK Jr. Backing the Researchers?

Anthropologist Peter Aaby founded the Bandim Health Project in 1978. It is now co-led by his wife, epidemiologist Christine Stabell Benn.

Kennedy has called the pair “the deities of vaccine research” at an anti-vaccine conference and cited their research on the diphtheria-tetanus-pertussis (DTP) vaccine. A subsequent study by the researchers produced different results.

Kennedy also called Aaby a “very famous” researcher on Joe Rogan’s podcast in 2023 and cited his work when he halted US funding to Gavi, the Vaccine Alliance.

Stabell Benn served on the hepatitis B working group of the US Advisory Committee on Immunization Practices (ACIP) and presented evidence before the committee voted to end the universal hepatitis B birth-dose recommendation. A federal judge subsequently stayed the decision.

With digital innovation, expanding healthcare access, and a growing focus on self-reliance driving transformation in India's healthcare sector, the Times Network India Health Summit & Awards 2026 is set to return for its third edition.

The event, to be held on October 28th, will bring together policymakers, healthcare leaders, clinicians, researchers, innovators, and industry stakeholders to discuss the future of India's healthcare ecosystem.

Centered on the theme, “The Blueprint for a Future-Ready Healthcare Ecosystem – Innovation. Access. Self-Reliance,” the summit will explore emerging healthcare innovations, collaborations, and policy approaches, culminating in an awards ceremony recognizing excellence across the sector.

As India is advancing in artificial intelligence (AI), digital health, biotechnology, medical technology (MedTech), and indigenous manufacturing, these areas will also be central to discussions on strengthening the country's healthcare ecosystem.

Summit At A Glance

Anupriya Patel, Union Minister of State for Health and Family Welfare and Minister of State for Chemicals and Fertilizers, is expected to attend as the chief guest.

The second edition of the Times Network India Health Summit & Awards 2026 will feature:

• 30+ speakers
• 400+ delegates
• 12+ knowledge sessions

Six Key Healthcare Discussion Areas

The summit will feature six panel discussions covering key areas of healthcare innovation, access, and policy.

• Advanced Healthcare Infrastructure And Clinical Excellence: Scaling advanced care through AI, Centres of Excellence, and digital innovation.
• Fertility And Reproductive Healthcare: Exploring reproductive technologies, precision medicine, and patient access.
• India's Biopharma Growth: Advancing research, therapeutics, and resilient manufacturing.
• Precision Diagnostics: Leveraging AI, genomics, and personalized care.
• Integrative Healthcare: Strengthening scientific research and AYUSH integration.
• Healthcare Financing: Improving affordability, access, and sustainability through insurance and public-private partnerships.

The summit is being held in association with Onextel Communications Media, co-powered by Novartis and supported by HealthandMe. It will conclude with a felicitation ceremony recognizing excellence across the healthcare sector.

Philadelphia Eagles quarterback Jalen Hurts is expected to miss the remainder of the 2026 NFL season after being diagnosed with deep vein thrombosis (DVT) and blood clots in both lungs.

In a statement on October 19, the team said the 28-year-old was clinically stable with no significant functional limitations. However, he needs blood thinners and cannot participate in contact sports while taking them.

His diagnosis raises questions about how blood clots travel from the legs to the lungs, why they are dangerous and how to reduce the risk.

What Happened To Jalen Hurts?

Hurts was initially diagnosed with a superficial blood clot in his left calf after reporting discomfort following a cleat injury during the October 4 game against the Los Angeles Rams.

Although doctors initially cleared him to play, a follow-up ultrasound in Philadelphia and further testing identified DVT and blood clots in both lungs, known as bilateral pulmonary emboli.

The team said his treatment would involve anticoagulants, or blood thinners. He can resume football activities once he stops taking the medication.

Also read: Hours Of Sitting, Gaming And Binge-Watching OTT? Doctors Warn Of Blood Clot Risk In Young People

What Is Deep Vein Thrombosis?

Deep vein thrombosis occurs when a blood clot forms in a deep vein, usually in the leg. If part of the clot breaks away and travels to the lungs, it can cause a pulmonary embolism (PE), a potentially life-threatening condition.

Prolonged sitting, hospitalization, bed rest, injuries and certain genetic factors can increase the risk of developing blood clots.

How Can A Leg Clot Travel To The Lungs?

A clot can break away from a deep vein in the leg, travel to the right side of the heart and then enter the arteries supplying the lungs. There, it can block blood flow and strain the heart.

“You have a clot in your leg. The problem is it can travel up the veins and go to your heart, and from there, go to your lungs, and block the blood vessels in your lungs,” CBS News chief medical correspondent Dr. Jon LaPook, who is not treating Hurts, told CBS Mornings.

“That's very serious,” he added.

Why Are Athletes At Risk Of Blood Clots?

Read More: World Thrombosis Day: Can An Unexplained Blood Clot Be The First Sign Of Cancer? Experts Explain

Hurts is not the first high-profile athlete to experience blood clots. Tennis star Serena Williams has a history of clots, while NBA Hall of Famer Chris Bosh retired early following blood-clot-related complications.

Fitness does not eliminate the risk. Injuries and prolonged immobility, including during long-haul flights, can slow blood flow and contribute to clot formation.

DJ Corey, director of Northeastern University’s EMT program, said extended periods of sitting during air or road travel can increase the risk because leg muscles help maintain blood circulation.

The US Centers for Disease Control and Prevention (CDC) also warns that limited mobility during long-distance travel can increase the risk of venous thromboembolism (VTE), which includes DVT and pulmonary embolism.

How Can Travellers Reduce Their Risk?

To improve circulation during long journeys, the CDC recommends:

• Moving the legs frequently while seated.
• Walking periodically when it is safe to do so.
• Avoiding prolonged immobility.
• Consulting a doctor about preventive measures if you have additional risk factors.

Compression stockings may help some travellers at increased risk, depending on their medical needs.

What Are The Warning Signs Of Blood Clots?

DVT symptoms can include leg swelling, pain, tenderness, warmth and skin discoloration. Some people may have no obvious symptoms.

Pulmonary embolism warning signs include sudden breathlessness, chest pain, a rapid heartbeat, lightheadedness and coughing up blood.

Sudden breathing difficulties, chest pain or fainting require immediate medical attention, as a pulmonary embolism can be life-threatening.