A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.

What Are The Drugs Involved

The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.

The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.

These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.

What Could This Mean For Bowel Cancer Treatment In The Future

The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.

All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.

One of the central healthcare issues surrounding the November 3 US midterm elections were abortion rights.

Voters in Virginia, Nevada and Missouri supported measures that protect access to abortion, while voters in Idaho voters rejected a proposal that could have formed new policies for reproductive healthcare freedom.

The results show how differently abortion access is being shaped across states after the US Supreme Court decided to overturn the constitutional right in 2022.

When Abortion Became A State-Level Issue In The US?

In 1973, the US Supreme Court recognised a constitutional right to abortion access in its landmark Roe v. Wade ruling. This meant states could not ban abortion before fetal viability, which is the point at which a foetus can survive outside the uterus.

That changed in June 2022, when the Supreme Court overturned Roe v. Wade through its ruling in Dobbs v. Jackson Women’s Health Organization.

The decision removed the federal constitutional protection and granted significant authority to regulate abortion rights to individual states.

Since then, US states have adopted different laws to control abortion rights. Some have introduced near-total bans, while others have added constitutional protections for abortion and enabled reproductive healthcare.

Also read: 2026 US Election Results: What Annie Andrews And Amy Acton’s Wins Could Mean For Healthcare In America

Virginia Voters Approve Constitutional Protection For Abortion

Virginia voters approved Question 1, a constitutional amendment protecting reproductive freedom, which includes access to abortion, contraception, prenatal care, childbirth, postpartum care, miscarriage management and fertility treatment.

The amendment also protects patients and healthcare professionals from punishment for their decisions related to reproductive healthcare.

It allows the state to regulate abortion during the third trimester, while granting exceptions when the pregnant person's health is at risk.

This has cemented Virginia's position as a pro-choice state, protecting reproductive healthcare access, particularly in the South, where several other states have imposed strict abortion regulations. The amendment is expected to take effect on January 1, 2027.

Also read: US Midterms 2026: 125 Doctors, Nurses And Health Experts Join Election Battle

Nevada Voters Supported Abortion Protection

Nevada voters approved Question 6, a measure that establishes constitutional right to abortion until fetal viability. After that point, abortion would remain permitted when necessary to protect the pregnant person's life or health.

The measure had also received voter approval in 2024. Nevada requires constitutional amendments to be approved in two successive elections before they can become part of the state constitution. The latest vote therefore clears the second hurdle.

Abortion was already legal in Nevada up to 24 weeks under a state law approved by voters in 1990. Question 6 provides an additional layer of protection by placing abortion rights in the state constitution, making them harder to change in the future.

Also read: US Midterm Elections 2026: Abortion, Medicaid, Measles And Healthcare Issues At Stake

Missouri Voters Reject Attempt To Roll Back Abortion Protections

Missouri voters rejected Amendment 3, which sought to repeal reproductive freedom protections approved by voters in 2024.

The proposed amendment would have significantly restricted abortion access, allowing it in very limited circumstances involving medical emergencies, fetal anomalies, and pregnancies resulting from rape or incest within the first 12 weeks.

With approximately 55% voting against the measure, the 2024 constitutional protections remain in place.

The result marks a second significant vote on abortion rights in Missouri in two years. In 2024, voters had approved the constitutional amendment that helped overturn the state's near-total abortion ban.

Idaho Voters Reject Proposal That Support Reproductive Freedom

Idaho voters rejected Proposition 1, which would have established a statutory right to make reproductive healthcare decisions, including abortion until fetal viability.

The proposal also covered contraception, fertility treatment, pregnancy-related care, childbirth and miscarriage treatment. It sought to create exceptions to the state's near-total abortion ban.

According to reports 55.4% voted against the measure and 44.6% voted in favour after about 85% of votes had been counted. With the proposal defeated, Idaho's existing near-total abortion ban remains in place.

The results do not just affect if abortion is legally available in a state, they also shape how patients and doctors navigate pregnancy healthcare. Restrictions can create uncertainty for doctors, especially when a pregnancy threatens a patient's health but does not clearly meet the legal definition of an emergency. This can affect time-sensitive treatment decisions related miscarriage management.

The climate crisis is also a major health crisis, but six proven measures could help prevent 1.6 million deaths every year, according to the World Health Organization (WHO).

A new WHO report, released ahead of COP31, highlights six climate and health interventions that could save lives while delivering trillions of dollars in economic and fiscal benefits.

“The climate crisis is a health crisis, but much of the harm it causes can be prevented with tools we already have,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General.

“This report shows that scaling up proven, affordable actions could save millions of lives, with the greatest gains in the countries that need them most. As governments prepare for the next round of climate negotiations, protecting health must be at the centre of climate action,” he added.

What Are The 6 Measures That Could Save 1.6 Million Lives?

Also read: Big Lancet Report: Heat-Related Deaths Rise 36% Since Paris Climate Agreement, Global Warming Blamed

The report estimates that scaling up the six actions globally could prevent 1.6 million deaths annually, equivalent to one in every 40 deaths, based on modelled projections.

The six measures include:

• Heat-health warning systems
• Climate-resilient drinking-water services
• Basic sanitation services
• Hygiene and handwashing facilities
• Cleaner household fuels and technologies for cooking and heating
• Efficient fossil fuel pricing policies

Together, these actions could also help avoid 16.7 billion tonnes of CO₂ emissions, equivalent to 31% of global annual greenhouse gas emissions, excluding land use, land-use change and forestry.

6 Climate Actions Could Deliver Trillions In Economic Benefits

Read More: Climate Change And Gut Health: How Heat, Drought And Unsafe Water Raise Risks, Global Experts Warn

Heat-health warning systems were the most cost-beneficial intervention assessed, generating an estimated US$835 in benefits for every US$1 invested. However, estimates varied across different scenarios and sensitivity analyses, ranging from US$364 to US$1,272 for every US$1 invested, the WHO said

Meanwhile, efficient fossil fuel pricing policies were estimated to deliver the largest overall economic welfare benefits, at US$3,041.10 billion. Estimates across different scenarios and sensitivity analyses ranged from US$690.59 billion to US$5,342.64 billion.

These policies were also projected to generate US$5,440.93 billion in fiscal benefits, with estimates ranging from US$3,442.96 billion to US$5,440.93 billion, the WHO said. The policies are also estimated to prevent 1.2 million deaths annually.

COP31: Health To Be A Key Focus

The 2026 United Nations Climate Change Conference, commonly known as COP31, will take place in Antalya, Türkiye, from November 9 to 20. The conference's dedicated COP31 Health Day will be held on November 9, the first day of the conference.

Governments are expected to share their climate reports and discuss ways to advance climate-resilient and environmentally sustainable health systems.

Former British Olympic sprinter Beth Dobbin, diagnosed with myalgic encephalomyelitis (ME), spends more than 22 hours a day in bed because of the debilitating condition. She is urging UK Prime Minister Andy Burnham to meet her and commit to increased government funding for ME research.

Following Dobbin's October 21 appeal, 360 sportspeople have signed a letter backing her campaign. The group includes 114 Olympians and Paralympians, who have won a combined 77 medals.

In a post on X, Dobbin expressed surprise at the response, saying: “I can’t believe 360 people signed in just 1 week, so many amazing names and messages still coming in of people wanting to add theirs (so feel free to message to add yours, we’re keeping on the pressure!!!)”

The 32-year-old retired from athletics in April 2026, describing her illness as “serious” and “life-changing”, BBC Sport reported. She had reached the 200m semi-finals at the Tokyo Olympics in 2021 and won bronze in the 4x200m relay with Scotland at the 2022 Commonwealth Games in Birmingham.

360 Sportspeople Back Beth Dobbin's Call For ME Research Funding

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Among the signatories are Everton manager David Moyes, United States women's national football team manager Emma Hayes, former Chelsea and England centre-back Millie Bright, athletes Laura Muir, Eilish McColgan and Adam Gemili, Olympic sprinter Dina Asher-Smith and diver Tom Daley.

The letter calls on Burnham to “level the playing field” for ME research funding compared with other illnesses and “give hope to the many affected that something is being done about this life-destroying, much-ignored illness and its spiralling impact”.

It highlights the disparity in government research funding between ME and other conditions.

“Between 2019 to 2024, UK government research funders committed just £6.6m in funding for research into ME, compared to £79.1m for Parkinson's and £496.4m for dementia,” the letter states.

It adds that biomedical research funding for ME was “almost non-existent” before this period and that the lack of investment has contributed to the absence of approved treatments.

How Did Beth Dobbin Develop ME?

Dobbin's health began deteriorating after back-to-back COVID-19 and glandular fever infections during the winter of 2021-22, she told BBC Sport.

She experienced worsening fatigue, slower running times and soreness in the glands in her neck and armpits. Initial tests by British Athletics doctors failed to identify the cause.

Despite her symptoms, she continued training in 2022. At the European Championships, she false-started after losing all feeling in her legs while in the starting blocks.

Her condition continued to worsen. She struggled to stand and spent most of her time in bed. After consulting four or five specialists, she was diagnosed with ME.

Dobbin has since been largely confined to her home and bed. Even conversations, bright lights and loud sounds can trigger a “crash” lasting days or, in severe cases, months. According to BBC Sport, she has left her house just five times this year, mainly for medical appointments and blood tests.

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What Is Myalgic Encephalomyelitis (ME)?

ME, also known as chronic fatigue syndrome (CFS), is a complex, chronic illness that can cause severe fatigue, pain, sleep disturbances and problems with thinking and memory.

Symptoms do not improve with rest and can fluctuate in severity. While some people can continue working or studying, others experience severe disability and may require round-the-clock care or tube feeding.

There is no known cure or specific approved treatment for ME. More than 400,000 people in the UK are thought to have the condition, although the actual number could exceed one million.

A Department of Health and Social Care spokesperson previously told BBC Sport: “Myalgic encephalomyelitis (ME) can have a devastating impact on people's lives, and we are determined to accelerate progress in understanding and treating this debilitating condition.”