A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.
What Are The Drugs Involved
The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.
The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.
These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.
What Could This Mean For Bowel Cancer Treatment In The Future
The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.
All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.
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The vaccine-preventable measles is surging worldwide, especially in the US. The outbreaks that began in Texas last year are now spreading to several other states, with Utah being the new center of the highly contagious disease.
The US, which eliminated measles in 2000, is also at great risk of losing its status, as the CDC reported 1,748 confirmed cases across 33 jurisdictions between January 1 and April 16, 2026. Over 94 per cent of these cases are linked to ongoing outbreaks, the CDC said.
While the best way to prevent infection remains the measles, mumps, and rubella (MMR) vaccine, anti-vaxxers, goaded by Health and Human Services Secretary Robert F. Kennedy Jr., have stayed away from the vaccine.
However, watching an outbreak rip through their state has made the deadly realities of the disease more concrete.
Amid the soaring cases, Bloomberg News reported a quiet change among anti-vaxxers, as they have started to question their own deeply held beliefs and the conspiracy theories that fueled them.
Many of them have taken the MMR vaccination and then also posted emotional TikTok videos aimed at the anti-vax crowd, saying, “You can change your mind”.
Read More: Measles Again On The Rise Globally: Is India At Risk?
In several measles hotspots, there has been an uptake in the MMR shot that is slowing down the outbreaks, the report said.
The health department in South Carolina saw a nearly 170 per cent increase in MMR immunizations at free clinics in January from the year prior and is close to declaring its outbreak over.
MMR vaccines jumped 15 per cent in Texas last year before the state declared its outbreak over in August. Utah’s health department has also recorded a bump in immunizations since last summer, a hopeful sign for the country’s most active current outbreak.
The report cited that doctors are playing a key role in trying to build trust with no pressure or judgment. They are easing the anti-vaxxers' concerns and giving them the crucial assurance that their choice is deeply personal and private.
“For whatever reason, they have different information,” Stuart Simko, a pediatrician in Greer, South Carolina, was quoted as saying.
“You don't have to tell anybody you gave your child any sort of vaccine,” Simko added.
Lisa Carroll, a physician in South Carolina and professor at the Edward Via College of Osteopathic Medicine, helps run a weekly outreach program at a local food pantry where she’s increasingly encountered more families asking about the MMR. Many of them aren’t explicitly anti-vaccine; they just don’t know much about the shot or where to get it, she said. It was just easier for some of them to sign an exemption form, the report said.
In these cases, education on the true risk and safety of the MMR has led to that change of mindset, Carroll said.
How Effective Is the Measles Vaccine? Who Needs A Booster Shot?
Also read: Vaccinated And Still Worried? Truth About Measles Vaccine Safety And Effectiveness
One dose of the MMR vaccine gives about 95 per cent protection against measles. If a second dose is given—usually between 4 and 6 years old—protection shoots up to about 99 per cent.
The vaccine is also 99 per cent effective against rubella and 88 per cent against mumps after the second dose. This is the reason why the two-dose schedule is the international norm. Indeed, measles vaccination alone is responsible for more than 60 per cent of all childhood lives saved by vaccines worldwide over the past 50 years.
In general, a measles vaccine booster may be advisable for:
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The UK Parliament has passed a “landmark bill” to ban smoking among children who were born on or after 1 January 2009.
Under the new Tobacco and Vapes Bill, people aged 17 or younger face a lifelong ban on buying cigarettes.
Both the House of Commons and Lords settled on a final draft of the legislation that aims to create a smoke-free generation.
Once it gets the royal assent, ministers will be able to regulate tobacco, vaping, and nicotine products, including their flavors as well as packaging.
“This afternoon marks the end of this bill’s journey throughout parliament. It is a landmark bill; it will create a smoke-free generation,” Health minister Baroness Merron told the House of Lords on Monday.
“It is, in fact, the biggest public health intervention in a generation, and I can assure all noble Lords it will save lives.”
Noting that the Bill “does upset a great many people in that industry”, including retailers", Lord Naseby, a Conservative former MP, called for "a proper understanding of how we educate people not to take up smoking”.
It was first proposed by former UK Prime Minister Rishi Sunak On 4 October 2023 at the Conservative Party conference in Manchester. He shared plans to phase out cigarette smoking in the UK by raising the minimum age to purchase cigarettes from 18 each year, every year, until eventually no person can legally buy cigarettes. A similar proposal was made by the Labour Party earlier that year.
Plans for the Tobacco and Vapes Bill, legislation implementing such a ban, were announced in the King's Speech during the 2023 State Opening of Parliament.
The bill passed its first reading on 20 March 2024 and its second reading on 16 April 2024.
Also read: Banning Tobacco Can Save 1.2 million Lives By 2095
On 24 October 2024, the new government announced a ban on the sale of single use vapes, effective from June 2025, in an effort to address environmental concerns and the rising prevalence of vaping among children.
Under the new Bill,
Also read: UK Bans Disposable Vape: Will This Really Stop Young People And Reduce Waste?
Smoking is the most common risk factor and the single biggest cause of preventable death for a host of diseases, ranging from respiratory diseases to tuberculosis to cancer.
Smoking damages the human body and causes
There are safer alternatives to aluminium foil. (Photo credit: iStock)
People use aluminium foil as a common cooking tool and food storage solution, which studies show to be safe for most people when used occasionally. The proper method of use determines whether it functions as the best solution for storing food over extended periods. People can store dry, uncooked items in foil because it creates fewer safety risks than keeping reactive foods for extended periods. Ms Aditi Prasad Apte, Senior Clinical Nutritionist at Aster RV Hospital, Bangalore, in an interview with Health and Me, spoke about the dangers of storing food in aluminium foil. The expert also shared alternatives that are safer and can be helpful.
People who eat food processed with aluminium may ingest small amounts of aluminium through their meals. The likelihood of this occurrence increases when particular conditions exist, which include using food that contains heat, acid, salt, or strong spices. These include tomatoes, citrus, vinegar, and strongly flavoured foods. Heat increases the transfer, which means that wrapping hot food directly in foil produces higher transfer rates than covering leftovers for short periods. One should understand that storing hot food in foil can create food safety issues because of aluminium contamination.
The use of foil creates an incomplete airtight seal, which results in insufficient cooling and creates unsafe storage conditions when food remains at dangerous temperatures for extended periods. The health risks connected to long-term excessive aluminium exposure have remained a topic of scientific discussion for many years. The bodies of healthy people process and remove aluminium consumed through food mainly via the kidneys.
People who have kidney problems must handle aluminium exposure with special caution. Research has studied the links between high aluminium exposure and neurological and bone problems, but has found no proof that using foil for daily activities leads to these medical issues. The larger issue requires people to take steps to reduce their exposure to unnecessary risks whenever possible.
Safer alternatives for routine storage include glass containers, stainless steel containers, ceramic storage, and food-grade silicone options. These products provide specific benefits for storing hot leftovers, acidic foods, and items that need to be kept in refrigerators for extended periods. Parchment paper may also be a better barrier than foil in some cooking situations.
There are also several myths worth clarifying. Some people believe that aluminium foil contains harmful substances that make it unsafe to use. Normal, occasional use is not the same as dangerous exposure. Another myth is that foil always reacts with food; in reality, reaction risk depends heavily on the type of food, temperature, and duration of contact.
The fact is that foil works better for wrapping food and providing temporary coverage than it does as a standard storage method. The best approach requires people to use aluminium foil appropriately in cooking situations. People should not store acidic or hot food in foil for extended periods, and they should not consume food that has come into contact with damaged foil. The safest approach for regular home use is to use foil only when necessary, while understanding which materials work better in specific situations.
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