Study Says Combined Drugs Can Shrink Tumour By 60 Percent In Bowel Cancer

Updated Jul 25, 2024 | 06:09 PM IST

SummaryA new study has found that combining the use of botanciiimab and balstilumab can reduce tumours caused by bowel cancer by 60%, marking the first time a durable response to immunotherapy has been reported in patients suffering from this condition.
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A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.

What Are The Drugs Involved

The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.

The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.

These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.

What Could This Mean For Bowel Cancer Treatment In The Future

The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.

All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.

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Football Legend Kevin Keegan Reveals Fighting Stage Four Cancer

Updated Jun 2, 2026 | 01:00 PM IST

SummaryFormer England captain and manager, football legend Kevin Keegan, reveals his ongoing struggle with stage four cancer. He addressed his fans at the Tyne Theatre and Opera House.
Football Legend Kevin Keegan Reveals Fighting Stage Four Cancer

Credit: AI Generated Image

One of the beloved football legends, Kevin Keegan, has revealed his ongoing fight with stage four cancer. The news of his health condition has brought on massive support and love from across the football-loving community. The man who inspired generations and contributed both as a player and manager comes forth and reveals that he is getting diagnosed with stage four stomach cancer, and the lethal disease has spread to his other body parts.

The news carried huge value as the former England captain himself talked about his health condition with his usual honesty and humor. The player hailed by his fans as "King Kev" addressed a huge audience in Newcastle. The 75-year-old veteran footballing genius unraveled his journey through the difficult times. His supporters also listened to his self-reflection on the situation completely in silence.

Former Newcastle forward and manager, standing at the Tyne Theatre and Opera House, said, "I was in a car accident and, through that, I had to have an operation. Whilst having the scan for the operation, they found out I had cancer. They said they had an absolute top doctor for fighting what you have got, which is stage four cancer."

"So I went to meet him. He's a Liverpool supporter, so I knew I wouldn't walk alone," he added and continued, "He said, 'Kevin, this new treatment, I've got a tremendous strike rate'. I said, "'What's your strike rate?' He said, '33%'. I thought it would be 80%, 90%. 33%!"

Keegan enjoyed great spells at Scunthorpe United, Liverpool, Hamburg, Southampton, and Newcastle during his illustrious career. Later, he led Newcastle, Fulham, England, and Manchester City.

The player, also popular for his perm hairstyle, was a famous face in British television as a guest on shows and part of an advertisement campaign. He also took part in a public information short-film teaching youngsters how to cross the road. He also brought several pop singles and had a memorable appearance on the television show Superstars.

Also Read: Potential 'Functional Cure' For Hepatitis B: Trial Give Hope To Millions

How To Reduce The Risk Of Cancer?

Consuming a healthy and balanced diet rich in fruits, vegetables, whole grains, and lean proteins can reduce cancer risk.

Regular physical activity keeps the body fit and reduces the risk of breast, colon, and endometrial cancers.

Smoking and alcohol consumption should be avoided.

Skin cancer is one of the most preventable types of cancer. Applying sunscreen with high SPF, finding shade, and avoiding tanning beds would save you from harmful ultraviolet rays.

Also Read: Space Grown Stem Cells: How Are Expedition 74 Astronauts Helping To Fight Cancer?

Long-term stress can weaken the immune system and may contribute to an increased risk of cancer. Incorporating stress-relief techniques such as mindfulness, practising deep-breathing exercises, and engaging in enjoyable hobbies can enhance overall well-being.

Exposure to environmental elements like pesticides, pollutants, and workplace chemicals can increase the risk of cancer. To avoid this risk, wearing protective gear, opting for organic produce, and ensuring adequate ventilation in living or working areas can greatly assist.

By vaccinating against Hepatitis B and HPV, individuals can protect themselves against infections closely linked to liver and cervical cancers; apart from vaccination, adopting proper hygiene practices and steering clear of high-risk activities can help prevent the risk of cancer-causing infections.

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Bangladesh's Measles Crisis Deepens: Nearly 600 Children Dead Since March, Infections Set To Surge

Updated Jun 2, 2026 | 11:00 AM IST

SummaryThe outbreak began in January in Rohingya refugee camps near the Myanmar border and has now reached 58 of Bangladesh’s 64 districts.
Bangladesh's Measles Crisis Deepens: Nearly 600 Children Dead Since March, Infections Set To Surge

Credit: iStock

Bangladesh’s deadliest measles outbreak is showing no signs of abating. Since March, the highly infectious disease has claimed nearly 600 children, while suspected cases have crossed 72,000.

What is more worrying is that there are no signs of a slowdown despite nationwide vaccination efforts, and experts believe infections could surge further following increased transmission during the Eid Al-Adha homecoming period.

“Over the weekend, Bangladesh documented more than 1,300 suspected measles cases and two deaths, pushing the country’s tally to nearly 71,000 infections and 585 fatalities since the outbreak began in mid-March,” according to the Bangladeshi Directorate General of Health Services (DGHS).

As many as 56,886 suspected measles patients have been hospitalized in Bangladesh since March 15, of whom 52,841 have recovered, according to the DGHS, United News of Bangladesh reported.

“There is no sign of a downtrend in measles infection rate across the country,” Dr. Ariful Bashar from Mohakhali Contagious Disease Hospital told Arab News.

“Measles is a highly contagious disease, even six times more than COVID-19. Unless 95 percent immunity is achieved through vaccination, there will be no downtrend in the infection rate,” he added.

Also read: Measles Again On The Rise Globally: Is India At Risk?

Notably, millions of Bangladeshis travelled to their hometowns last week to celebrate Eid Al-Adha.

Bashar said that “as health protocols were not maintained properly”, the country is likely to “witness a future increase in the infection rate”.

The expert noted that Bangladesh also lacks facilities for efficient contact tracing of measles patients, which could further increase the spread of what he described as “the most contagious disease in the world”.

Hospitals Overwhelmed

Since March, hospitals across the country have been overwhelmed as they struggle to isolate and treat hundreds of children admitted every day.

Dr. Mirza Ziaul Islam, director of the Bangladesh Shishu Hospital and Institute, told Arab News that “during the Eid travel period, it was not possible to keep infected patients isolated”, increasing the risk of further transmission.

Also read: India Concerned Over Measles Outbreak, Action Underway: Dr N K Arora| Exclusive

Most Cases And Deaths Among Young Children

Four out of five measles patients are younger than five years, according to The New York Times. The vast majority of deaths have also occurred in this age group, which is highly vulnerable to the airborne virus.

According to the United Nations International Children's Emergency Fund (UNICEF), Bangladesh had largely contained measles outbreaks since the 1990s through vaccination campaigns. However, immunization efforts were disrupted in 2024 after student-led protests overthrew the government.

The interim administration that governed Bangladesh until elections in late February did not conduct a supplementary mass vaccination campaign as recommended.

Last week, UNICEF said it had repeatedly warned the country’s interim government, led by Muhammad Yunus, through written communications and meetings with Health Ministry officials about vaccine shortages that could trigger a major health crisis, local media reported.

Vaccination Drive Underway

In April, Bangladesh’s new government launched an emergency campaign to vaccinate 20 million children.

Although the campaign has reportedly achieved 110 percent of its target and remains ongoing, experts note that only one of the two doses required for strong and durable immunity has been administered so far.

In addition, it takes four to six weeks for immunity to develop after vaccination.

Outbreak Spreads Nationwide

The outbreak began in January in Rohingya refugee camps near the Myanmar border and quickly spread nationwide. It has now reached 58 of Bangladesh’s 64 districts, causing more than 21,000 hospitalisations.

In an April 23 update, the World Health Organization (WHO) warned of a “considerable risk” of spread to Myanmar, where civil strife has disrupted immunisation efforts, and to India, which remains vulnerable. WHO described the outbreak as “a reversal from Bangladesh’s previous progress towards measles elimination.”

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Meet Vaxira: The Cuban Vaccine Against Deadly Lung Cancer

Updated Jun 2, 2026 | 10:22 AM IST

Summary​According to the Cuban Embassy in the US, the vaccine "works by mimicking a molecule found on cancer cells but almost entirely absent in healthy human tissue". It also targets tumors with remarkable precision and has very few side effects.
Meet Vaxira: The Cuban Vaccine Against Deadly Lung Cancer

Credit: @EmbaCubaUS/X

Scientists in Cuba have developed a novel vaccine against lung cancer that has shown the potential to improve survival rates among people living with the disease.

The vaccine, chemically known as racotumomab, has been developed in collaboration with scientists from Argentina. Vaxira has been approved in Cuba and Argentina for advanced non-small cell lung cancer (NSCLC).

How Does Vaxira Work?

It helps the immune system recognize and destroy lung cancer cells.

According to the Cuban Embassy in the US, the vaccine "works by mimicking a molecule found on cancer cells but almost entirely absent in healthy human tissue". It also targets tumors with remarkable precision and has very few side effects.

While advanced NSCLC has limited curative options and poor survival rates, clinical trials of Vaxira showed a significant improvement in survival.

Notably, "one-year survival among patients receiving the vaccine nearly doubled compared with the control group," the post said.

"Real-world data shows median survival of up to 24.5 months in maintenance therapy," it added.

Improved Survival And Minimal Side Effects

Importantly, the vaccine has demonstrated minimal side effects and is considered suitable for long-term use.

The embassy described the vaccine as affordable and accessible compared with many immunotherapies.

In 2025, Vaxira also received Cuba's National Technological Innovation Award.

The commercial rollout of Vaxira is being facilitated by the international public-private consortium ReComBio, linking Havana's Center of Molecular Immunology (CIM) with Argentina's Elea Laboratories.

Also read: Potential 'Functional Cure' For Hepatitis B: Trial Give Hope To Millions

What Is Lung Cancer?

Lung Cancer is one of the most common and serious types of cancer. It is also the leading cause of cancer-related deaths worldwide, with approximately 2.5 million new cases and 1.8 million deaths reported in 2022.

According to the American Cancer Society, lung cancer mainly occurs in older people. Most people diagnosed with lung cancer are 65 or older; a very small number of people diagnosed are younger than 45.

The average age of people when diagnosed is about 70.

It is also the leading cause of cancer death in the US, accounting for about 1 in 5 of all cancer deaths.

The two main types of lung cancers are:

Non-small-cell lung cancer (NSCLC): This is the most common form, making up about 80–85% of all cases. NSCLC includes three subtypes:

  • Squamous cell carcinoma
  • Adenocarcinoma
  • Large-cell carcinoma

Small-cell lung cancer (SCLC): Less common than NSCLC, this type tends to grow and spread more quickly.

Early Signs and Symptoms to Look Out For

Lung cancer symptoms can mimic less serious conditions, which is why they’re often dismissed or misdiagnosed. If you experience the following symptoms persistently, don’t ignore them—regardless of your age or smoking history:

  • Chest pain or discomfort
  • Unexplained shortness of breath
  • Persistent cough or wheezing
  • Shoulder, back, or rib pain
  • Fatigue or sudden weight loss
  • Blood in sputum (though not always present).

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