A new study has found that a combination of two drugs could enhance the immune system to treat one of the most common types of cancer in the world, bowel cancer. Also known as colorectal cancer, despite its widespread presence, the treatment options for this condition are limited. What the study specifically found was that this procedure could shrink the tumours caused by this condition by around 60%.
What Are The Drugs Involved
The trial involved the use of two immunotherapy drugs, botancilimab and balstilumab. It is a monoclonal antibody that works to stimulate the body's immune system to attack cancer. The study is a rather significant find, as it’s the first time that a consistent and durable response to immunotherapy has been reported in patients with solid MSS mCRC tumours.
The study was divided into several phases for more than 6 months. In the US trial, around around 101 patients with microsatile stable metastatic colorectal (MSS-mCRC) tumours showed a decrease . Around 61% of the patients experienced tumour shrinkage or stabilization after combined treatment with votancilumab and balstilumab. When it comes to downsides, diarrhea and fatigue were found to be the most common side effects or side effects of this drug.
These results are interesting and open to exploration. To date, immunotherapy has not been effective in patients with CNS-mCRC tumors. This study demonstrates the potential of the combination of botenlimab and balstilimab in the treatment of CNS mCRC, providing new hope for people diagnosed with colon cancer.
What Could This Mean For Bowel Cancer Treatment In The Future
The study is currently in the final stages of clinical trials, and the US Food and Drug Administration (FDA) hopes to quickly gain approval for its use because of the importance of this area that affects many people. The efficiency shown demonstrates the potential of botansilimab to contribute to broad antitumor immunity.
All in all, the combination of botensilimab and balstilimab represents a promising new direction in the treatment of colorectal cancer. This breakthrough could improve conditions for many patients worldwide and lights a new hope in the fight against this common disease. The results of this study show the effectiveness of immunotherapy in this field and how its potential to transform cancer treatment can only grow in the years to come.
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A Florida man has filed a lawsuit against OpenAI and its CEO Sam Altman, alleging that medical advice provided by ChatGPT nearly cost him his life after the chatbot repeatedly discouraged him from seeking medical care.
Scott Winters, a former pastor, filed the lawsuit in San Francisco County Superior Court, claiming ChatGPT repeatedly advised him against seeking medical help as he experienced symptoms leading up to a near-fatal pulmonary embolism—a sudden and dangerous blockage in an artery in the lungs.
"ChatGPT-4o frequently opined on and evaluated Scott's physical condition, conveying the authority and confidence of a medical professional rendering a clinical assessment and treatment recommendation, despite not having the qualifications to do so," the lawsuit states.
Winters' lawyers further allege that the platform "repeatedly and insistently misdiagnosed" him while drawing on previous discussions about religion to reassure him that he would recover.
Also read: AI Cannot Replace Doctors, It Can Only Complement, Says Dr Santosh Sivaranjani
According to the lawsuit, Winters became a regular ChatGPT user and gradually came to rely on the chatbot for medical advice, resisting repeated efforts by family members and friends to persuade him to visit a hospital.
Weeks before becoming critically ill, he consulted ChatGPT about recurring dizzy spells and "bouts of blood pressure instability."
The lawsuit claims that in one response, ChatGPT advised Winters to remain in the recliner chair to which he had become "mainly confined to" because of his worsening health.
Court documents state that Winters later suffered a "massive pulmonary embolism due to multiple blood clots in both of his lungs that brought him to the brink of death, one that his doctors stated was likely brought on because of his immobility."
Winters is seeking financial damages and is asking the court to require OpenAI to implement "reasonable safeguards that protect other users from harm."
Read More: Women Turning to AI for Health Detection: Helpful Tool or Risky Trend?
Earlier this year, OpenAI launched a new ChatGPT Health feature in the US that can analyze users' medical records to provide more personalised responses, although campaigners have raised privacy concerns.
At the time, OpenAI said more than 230 million people ask ChatGPT questions about their health and wellbeing every week. In a blog post, the company said ChatGPT Health offers "enhanced privacy to protect sensitive data."
"ChatGPT is not a doctor and should never be used as a substitute for medical care, diagnosis or treatment," OpenAI spokesperson Drew Pusateri told CBS News, reacting to allegations.
He added: "AI can make that experience better by helping them find clearer answers, organize their questions and prepare for conversations with medical professionals."
ChatGPT's terms of use state that users should not treat the chatbot as a "sole source of truth," particularly for decisions that could "have a legal or material impact on that person, such as making credit, educational, employment, housing, insurance, legal, medical, or other important decisions about them."
This is not the first lawsuit OpenAI has faced over users' health and safety.
In May, a Texas couple whose son died from an overdose after seeking information about drugs from ChatGPT sued OpenAI, alleging he would still be alive if the company had not "bypassed safety guards."
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Sri Lanka is facing its worst dengue outbreak in over a decade, with 76,044 cases and 56 deaths reported so far in 2026, according to the National Dengue Control Unit (NDCU).
With the onset of the monsoon season, infections have surged sharply. While 8,590 cases were reported in May, the number more than doubled to 21,537 in June. In the first 19 days of July alone, 20,666 cases were recorded, including 2,895 new infections on July 21, the NDCU said.
The country has reported 56 dengue-related deaths this year, with a case fatality rate of 0.07%. According to the World Health Organization (WHO), global dengue cases have risen from around 500,000 in 2000 to 14.4 million in 2024.
Western Province Worst Hit
Sri Lanka's Western Province remains the hardest-hit region, accounting for more than half of all infections nationwide. Health officials have also identified 162 high-risk areas for dengue transmission, Asia News reported.
According to the NDCU, the Ministry of Health is currently conducting surveillance programmes across 63 high-risk divisions. The country is also deploying military drones to identify stagnant water on rooftops and other mosquito breeding sites.
Public Health System Under Pressure
According to Reuters, Sri Lanka's public health services and hospitals are battling the country's worst dengue outbreak in nearly a decade, with the armed forces assisting efforts to contain the spread.
The response includes air force drones tracking rooftop pools of stagnant water after monsoon rains, while military and police personnel are helping inspect homes, construction sites and schools to eliminate mosquito breeding grounds.
Public health workers were "stretched to their limit," said Kapila Kannangara, Acting Director General of the National Dengue Control Unit.
"The number of patients is high, and the severity of the cases is high," he said, adding that about 75% of cases are linked to the more virulent DENV-2 strain, which is spreading rapidly.
Health officials expect infections to decline as monsoon rains weaken in August but warn that cases could rise again from November with the arrival of the island's second annual monsoon season.
What Is Dengue?
Dengue is a viral infection transmitted primarily by Aedes mosquitoes and is common in tropical and subtropical regions worldwide.
Most infections cause high fever and flu-like illness. However, some cases can progress to severe dengue (dengue hemorrhagic fever), which may lead to severe bleeding, shock and death.
Dengue is the most widespread viral disease transmitted by Aedes mosquitoes. More than 3.9 billion people across over 132 countries are at risk, with an estimated 96 million symptomatic cases and around 40,000 deaths reported each year globally.
Symptoms of Dengue Fever
Symptoms usually appear 4–10 days after the bite of an infected mosquito and may include:
In severe cases, dengue can cause excessive bleeding, a sudden drop in blood pressure and organ complications.
How to Prevent Dengue
Preventing dengue focuses on avoiding mosquito bites and eliminating breeding sites. Measures include:
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The US Centers for Disease Control and Prevention (CDC) and the UK Health Security Agency (UKHSA) have issued travel health advisories warning travelers about the growing risks of mosquito-borne diseases, including chikungunya and yellow fever.
The CDC has issued a Level 2 Travel Health Notice for Costa Rica following a chikungunya outbreak, while UK health authorities have alerted travelers about rising imported chikungunya cases and yellow fever activity across multiple countries.
The CDC warned American travelers to "practice enhanced precautions" after Costa Rica reported a chikungunya outbreak.
On July 1, Costa Rica's Ministry of Health declared an active outbreak in the oceanside community of Playa Langosta in the western province of Guanacaste..
An epidemiological survey identified 45 suspected cases, of which four were laboratory confirmed, while 17 others were considered likely linked to the outbreak.
According to the US Embassy in Costa Rica, the cases include both Costa Rican nationals and foreign visitors. The embassy said local transmission means the virus is now circulating among the local mosquito population rather than being limited to infected travelers.
Costa Rica has reported 16 total cases this year, with the previous reported case dating back to 2017.
The UK Health Security Agency issued a warning for holidaymakers travelling to affected regions as imported chikungunya cases continue to rise.
"Are you, or someone you know, heading off on a tropical trip? It's worth being aware of chikungunya, a mosquito-borne virus that can cause severe joint pain. Check out our blog post to learn how to stay protected," the UKHSA said in a post on X.
UKHSA reported 112 confirmed and probable chikungunya cases among travelers returning to England, Wales and Northern Ireland in 2024—almost one and a half times the number reported in 2023.
"Travel to India accounted for the majority of these cases, followed by travel to Pakistan and Brazil – all popular destinations for people travelling from the UK," the agency added.
The UK government-backed Travel Health Pro has also warned travelers about increasing yellow fever activity.
Since the beginning of 2026, 95 confirmed yellow fever cases have been reported globally.
Confirmed cases have been reported in:
Chikungunya is a mosquito-borne viral disease transmitted primarily by Aedes aegypti and Aedes albopictus mosquitoes, the same mosquitoes that spread dengue fever.
Symptoms usually appear three to seven days after an infected mosquito bite and include:
Unlike dengue, chikungunya can leave lingering effects, with joint pain and fatigue lasting for weeks, months or even years.
People at higher risk of severe illness include:
The mosquitoes responsible for spreading chikungunya commonly breed in stagnant water found in overhead tanks, coolers and unused containers.
Yellow fever is a viral disease transmitted through the bite of infected mosquitoes. The infection can be severe and may become fatal in some cases if not managed appropriately. Vaccination is recommended before travelling to certain affected regions.
Initial Symptoms
Severe Symptoms
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