Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.

Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.

Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.

Potential Risks of TTTS

If left untreated, TTTS can have devastating consequences. Medical research indicates that:

• 90% of the cases of untreated TTTS lead to loss of one or both twins.
• Despite treatment, only a 70% survival rate for both twins is assured.
• Severe forms can result in preterm labor, cardiac failure in the recipient twin, and organ failure in the donor twin.
• Complications in long-term survivors include neurological damage and developmental delay in surviving infants.

TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.

Why Identical Twin Pregnancies Are More Complicated

Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.

Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.

Other Twin Pregnancy Health Risks

Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:

1. Premature Birth

Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.

2. Gestational Hypertension and Preeclampsia

Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.

3. Anemia

Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.

4. Birth Defects

According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.

5. Amniotic Fluid Imbalances

When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.

6. Postpartum Hemorrhage

Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.

Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."

Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.

Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.

The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.

Breast cancer has quietly become one of India’s most pressing public health challenges. Today, it is the most commonly diagnosed cancer among Indian women and a leading cause of cancer-related deaths.

Data from the Global Cancer Observatory shows that nearly 1.9 lakh women are diagnosed with breast cancer in India each year. This works out to one new case every four minutes. The death toll is equally worrying. On average, a woman in India dies of breast cancer every eight minutes, highlighting how urgently the country needs stronger awareness, early diagnosis, and sustained care.

One factor that sets India apart is the age at which women are affected. Almost half of all breast cancer patients in the country are younger than 45. This is a much higher proportion than seen in many Western nations, where the disease is usually detected later in life.

Breast Cancer: A Rising Burden Across The Country

Cancer surveillance data from GLOBOCAN and Indian registries under the Indian Council of Medical Research point to a steady rise in breast cancer cases. Rapid urbanisation, changing lifestyles, delayed pregnancies, shorter periods of breastfeeding, rising obesity, and limited screening practices have all played a role.

Late diagnosis continues to be one of the biggest challenges. Many women seek medical help only when the disease has progressed to advanced stages, making treatment more difficult and outcomes less certain. Fear, social stigma, lack of awareness, and limited access to screening services, especially in rural and semi-urban areas, often contribute to these delays.

For some women, the risk of recurrence can be significant, depending on the type and stage of cancer. Living with this uncertainty takes a lasting toll on mental and emotional wellbeing.

Novartis 'Take Charge' Campaign Focuses On Life Beyond Diagnosis

To address these gaps, Novartis has launched the ‘Take Charge’ campaign in collaboration with Times Network. The initiative aims to move the conversation beyond diagnosis and medication, encouraging women and their families to play an active role in decisions about care, recovery, and quality of life.

Speaking at the Times Network India Health Summit and Awards 2025, Amitabh Dubey, Country President and Managing Director of Novartis India, underlined that effective cancer care goes far beyond medicines alone. He spoke about the need for personalised treatment, open conversations between doctors and patients, and long-term support throughout the cancer journey.

According to Amitabh Dubey, advances in medical science have changed the way many cancers are managed. In breast cancer, better imaging, improved diagnostics, genomics, and targeted therapies now allow doctors to tailor treatment to the biology of each patient rather than relying on a uniform approach.

'Take Charge' By Novartis Highlights Need For Early Awareness

Awareness remains a central pillar of the ‘Take Charge’ initiative. Many women hesitate to speak openly about breast health or postpone seeing a doctor even after noticing symptoms. Encouraging routine self-examinations, timely screenings, and honest conversations about warning signs is especially important for younger women, who may not believe they are at risk.

The campaign also places strong emphasis on caregivers and families. Emotional support, access to reliable information, and timely medical advice can make a meaningful difference to both treatment outcomes and recovery.

Breast Cancer Awareness: Closing Gaps In Access And Affordability

Although government schemes such as Ayushman Bharat and various state cancer programmes have improved access to care, health insurance coverage in India remains limited, reaching only about 38 percent of the population. As a result, newer and more advanced treatments are still beyond the reach of many patients.

Novartis has been working with government agencies and local health systems to improve referral pathways, strengthen early detection efforts, and train frontline health workers. Community-based initiatives involving ASHA workers, awareness drives, and structured referrals aim to ensure that women with early symptoms reach appropriate care without unnecessary delays.

Breast cancer does not have to signal the end of a woman’s life or identity. With early diagnosis, personalised treatment, and continued support, many women go on to live full and meaningful lives. Campaigns like Take Charge seek to reinforce this message and remind women that they can remain active decision-makers in their own health journeys.

As Amitabh Dubey noted at the launch, taking charge is not only about fighting disease. It is about having the knowledge, confidence, and support to ask the right questions, make informed choices, and live well beyond cancer.

Schizophrenia (SCZ), bipolar disorder (BD) and major depressive disorder may share the same genetic roots, a Nature study shows.

While experts have long classified each of these mental disorders as individual illnesses with their own causes, researchers from across China have discovered that these three diseases share about 70 percent common genetic and environmental risk factors.

Schizophrenia is a severe, chronic brain disorder that can lead psychosis, hallucinations, delusions, disorganized thinking and reduced emotional expression. It can affect how a person's thinks, feels and behaves, making it hard to distinguish reality.

While bipolar disorder is a chronic mental illness which causes extreme mood swings, from emotional highs (mania/hypomania) to lows (depression), affecting the brain's energy, activity and focus levels.

On the other hand, major depressive disorder or clinical depression, is a serious mood disorder that causes persistent sadness and loss of interest in a person. It can affect feelings, thoughts and daily activities and can be identified by symptoms such as low energy, sleep/appetite changes, guilt, concentration issues and thoughts of death.

What Did The Study Find?

Using advanced techniques, they identified 238 genetic variants that raise risk across multiple disorders and showed that five major genetic patterns explain most of the differences between people with and without mental illness.

Read More: Study Shows Depression Can Accelerate The Onset Of Chronic Illnesses

Based on these genetic patterns, the disorders clustered into five broad groups: internalizing conditions such as depression, anxiety and post-traumatic stress disorder; neurodevelopmental conditions including autism and attention-deficit hyperactivity disorder; substance use disorders; compulsive conditions such as obsessive-compulsive disorder and anorexia and lastly, a fifth group that included bipolar disorder and schizophrenia.

The findings explain why many individuals are diagnosed with more than one mental health condition as many genes affect multiple brain pathways. This indicates that the same genetic changes can lead to different disorders depending on other biological and environmental factors.

Can The Same Treatment Plan Be Used For These Illnesses?

Even though medications such as antidepressants are useful in treating multiple mental illnesses including depression, anxiety and PTSD, the researchers concluded that more research is needed to understand the biology behind the genetic factors to understand the links between the disease.

One of the study’s authors compared the current system to diagnosing a patient with separate illnesses for a cough, sore throat and runny nose instead of recognizing a single underlying infection.

Nearly one in eight people globally, around 970 million individuals, were living with a mental disorder in 2021, with anxiety and depression being the most common globally.

Amazon has confirmed that 10 employees at its Coventry, UK warehouse have tested positive for tuberculosis (TB) as calls for site shutdown continue to grow.

Cases emerged at the hub, which has about 3,000 employees, in September 2025 and were found to be non-contagious. However, the retail giant acknowledged the breakout on January 16.

Officials from Amazon noted: "In line with best practice safety procedures, we immediately followed guidance from the NHS and UK Health Security Agency (UKHSA) and made all potentially affected employees aware of the situation. Out of an abundance of caution, we are currently running an expanded screening program with the NHS.

"We will continue to follow guidance from the experts in the NHS, and would respectfully remind public organizations of the need for responsible communications where matters of public wellbeing are concerned."

A spokesperson also assured that no new cases have been recorded in the area and a "screening program" being carried out amid "an abundance of caution" in collaboration with NHS and the UK Health Security Agency (UKHSA).

Are The Patients Receiving Treatment?

Since being diagnosed with TB, the unidentified patients have been receiving treatment from the UKHSA in West Midlands. Dr Roger Gajraj, consultant in health protection with UKHSA West Midlands also revealed that tests are being offered to those who may have had close contact with the patients and assured the overall risk remains low.

He told the BBC: "The small number of individuals affected by tuberculosis (TB) are responding well to treatment and are no longer infectious, so pose no onward risk.

"As a precaution, and in line with national guidance, we are offering testing to those who may have had closer contact with the affected individuals. The overall risk remains low. TB is fully treatable with antibiotics. We continue to work closely with Amazon to monitor the situation."

Read More: WHO’s Latest TB Guidelines Highlight Nutrition as Key to Treatment

Why Is TB Dangerous?

Common signs and symptoms of TB include unexplained weight loss, loss of appetite, chills and fever, fatigue, getting night sweats, weakness or fatigue. Symptoms of TB disease in the lungs may include coughing up blood or sputum, a cough lasting for more than 3 weeks and chest pain.

TB is typically diagnosed through the Mantoux Tuberculin Skin Test(TST). Here, a small amount of tuberculin is injected into the skin of the forearm and is monitored for a reaction 48 to 72 hours after the injection. A positive skin test result indicates the presence of TB and there is a need for additional tests to determine to determine if it is active or latent.

If positive, blood tests are done to determine or rule out if the patient has active or latent TB. There are two blood tests approved by the Food and Drug Administration for TB- T-SPOT TB test(T-spot) and the QuantiFERON-TB Gold-In-Tube test(QFT-GIT). Doctors may also prescribe a chest X-ray or CT scan after a positive skin test.

Despite being preventable through vaccine and and curable through antibiotics, TB remains a leading infectious killer and causes over a million deaths annually worldwide, with millions falling ill each year.

In 2024, about 10.7 million people were diagnosed with TB out of which 1.23 million died from the disease.