Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.

Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.

Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.

Potential Risks of TTTS

If left untreated, TTTS can have devastating consequences. Medical research indicates that:

• 90% of the cases of untreated TTTS lead to loss of one or both twins.
• Despite treatment, only a 70% survival rate for both twins is assured.
• Severe forms can result in preterm labor, cardiac failure in the recipient twin, and organ failure in the donor twin.
• Complications in long-term survivors include neurological damage and developmental delay in surviving infants.

TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.

Why Identical Twin Pregnancies Are More Complicated

Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.

Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.

Other Twin Pregnancy Health Risks

Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:

1. Premature Birth

Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.

2. Gestational Hypertension and Preeclampsia

Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.

3. Anemia

Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.

4. Birth Defects

According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.

5. Amniotic Fluid Imbalances

When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.

6. Postpartum Hemorrhage

Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.

Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."

Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.

Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.

The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.

US Department of Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. has announced food policy reforms as part of efforts to implement President Donald Trump’s Make America Healthy Again (MAHA) initiative.

The proposed measures focus on two areas: greater oversight of food ingredients and establishing a standardized federal definition of ultra-processed foods.

As per Kennedy, “nearly 60% of the American diet is made up of ultra-processed foods, and childhood obesity now affects more than one in five American children”.

To counter this, transforming the food system is key, he said.

“These historic actions bring greater transparency to what’s in our food and stronger science to federal nutrition policy. President Trump and I promised to Make America Healthy Again, and today we are turning that promise into policy,” Kennedy said.

What Are the Proposed Changes?

HHS has proposed a rule that would require manufacturers to notify the US Food and Drug Administration (FDA) when they determine that a substance added to human or animal food is Generally Recognized as Safe (GRAS).

In addition, HHS and the US Department of Agriculture (USDA) have submitted for final review the federal government’s first proposed definition of ultra-processed foods (UPFs).

Acting FDA Commissioner Kyle Diamantas said the measures are intended to increase transparency and strengthen science-based oversight of ingredients entering the food supply.

“By proposing mandatory GRAS notifications, we are closing critical information gaps and giving the FDA greater visibility into substances entering the food supply,” Diamantas said.

He added that the proposed UPF definition could provide a stronger foundation for future nutrition research.

What Is GRAS?

GRAS stands for Generally Recognized as Safe. It refers to substances that are considered safe by qualified experts for their intended use and are therefore exempt from the standard premarket approval requirements for food additives.

Examples of GRAS ingredients include canola oil, vinegar and spices such as black pepper.

Under the proposed rule, manufacturers would be required to notify the FDA when they conclude that a substance qualifies as GRAS. The agency would also expand its public-facing inventory of submitted GRAS notices.

According to Diamantas, mandatory notifications would help close information gaps and give the FDA greater visibility into substances entering the food supply.

First Federal Definition of Ultra-Processed Foods

HHS and USDA have submitted for final review the federal government’s first proposed definition of ultra-processed foods.

Research has linked high consumption of UPFs with preventable chronic diseases, including type 2 diabetes and heart disease. However, the absence of a standardized federal definition has made it difficult to maintain consistency in research across federal agencies.

The proposed definition incorporates feedback from thousands of stakeholders, including industry representatives, consumer organizations, researchers and members of the public.

Diamantas said the definition could help “create a stronger foundation for future nutrition research.”

How Does This Support Trump’s MAHA Agenda?

The measures are part of the Trump administration’s Make America Healthy Again Strategy and build on efforts to strengthen nutrition science, improve transparency and modernize oversight of the US food supply.

HHS also encouraged Congress to build on these efforts through legislation aimed at further strengthening the safety of the American food supply.

The death toll from Ebola has crossed 2,000 in the Democratic Republic of the Congo (DRC), three months after the outbreak was officially declared in May.

The outbreak has caused 4,381 confirmed cases across five provinces, making it the fastest-growing Ebola outbreak recorded in the Central African country. The response has been complicated by strikes by unpaid health workers, misinformation and cultural practices.

Ebola Virus Outbreak Began in February

The outbreak is caused by the rare Bundibugyo strain of Ebola, for which there is currently no approved treatment or vaccine.

According to the World Health Organization (WHO), the virus first emerged in the DRC in February, about three months before the outbreak was officially declared in the DRC and neighboring Uganda on May 15.

Some early patients were reportedly treated for malaria or typhoid, which can initially cause fever, weakness, vomiting and diarrhea. Early testing also focused on the more common Zaire strain of Ebola, delaying recognition of the Bundibugyo virus.

By early May, WHO had identified an unusual cluster of severe illness and deaths in the Mongbwalu health zone in Ituri Province. An investigation covering April 15 to May 13 subsequently identified 246 suspected cases and 65 deaths across three health zones.

The response has also been affected by conditions in Ituri, including armed conflict, population displacement and poor road access. Health workers have faced shortages of protective equipment, while some healthcare facilities have been affected by workers' strikes.

Zoonotic Spillover Likely Triggered the Outbreak

A new study published in Nature Medicine suggests that the outbreak began through a zoonotic spillover event, meaning the virus jumped from animals to humans before spreading between people.

Researchers from Congo, Uganda, Belgium and other countries found that the outbreak strain was genetically distinct from Bundibugyo Ebola viruses identified during previous outbreaks in 2007 and 2012.

The findings are consistent with a new animal-to-human transmission event, followed by sustained human-to-human transmission.

The study did not identify the specific animal source. However, Ebola viruses are known to periodically spill over from infected animals into human populations.

Genetic analysis also confirmed that cases detected in Uganda were linked to the outbreak in Congo.

How Was the Study Conducted?

Bundibugyo virus disease (BVD) outbreaks were previously recorded in 2007–2008 in Bundibugyo District, Uganda, and in 2012 in Isiro, DRC.

For the 2026 outbreak, researchers generated 22 viral genomes from samples collected from patients with BVD in the DRC and Uganda.

The genomes formed a well-supported phylogenetic cluster separate from variants associated with the 2007 and 2012 outbreaks. The analysis also showed evidence of sustained human-to-human transmission.

The researchers called for greater decentralized laboratory diagnostic capacity, including pan-Orthoebolavirus testing and genomic sequencing, to improve early detection and control of future outbreaks.

How Does Ebola Spread From Animals to Humans?

Ebola can jump to humans from infected animals such as bats, monkeys and apes. Transmission can occur through contact with blood, body fluids, excrement or raw meat during hunting and butchering.

Once the virus enters the human population, it can spread from person to person through contact with infected bodily fluids.

Symptoms of Bundibugyo Virus Disease

Symptoms of Bundibugyo virus disease are similar to those caused by other Ebola viruses and can include:

• Fever
• Headache
• Muscle pain
• Weakness
• Diarrhea
• Vomiting
• Stomach pain
• Unexplained bleeding or bruising, usually in later stages of illness

What if one blood sample could detect symptoms of multiple cancers at once, while also disclosing which organ may be affected? A new study from UCLA has brought that possibility a step closer to reality.

Researchers have at UCLA have developed a blood test called MethylScan that can detect molecular signals linked to multiple cancers and other diseases by analysing DNA fragments circulating in the bloodstream.

The findings, published in the Proceedings of the National Academy of Sciences, suggest the test could offer a simpler and potentially cheaper way to screen for serious diseases like cancer before their symptoms appear.

How Can One Blood Test Detect Different Cancers?

A blood test may be able to detect multiple cancers at once due to cell-free DNA (cfDNA). Every day, billions of cells die and release tiny fragments of DNA into the bloodstream. These fragments carry information about where they came from and what is happening in that tissue.

Instead of primarily searching for cancer-causing mutations, MethylScan looks at DNA methylation, a type of chemical tags that regulate how genes behave.

Different organs have distinct methylation patterns, and those patterns can change when cells become cancerous or diseased.

“DNA methylation reflects the health status of a tissue. It’s a very informative signal,” said Dr Wenyuan Li, professor of pathology and laboratory medicine at UCLA.

The researchers also developed a method to filter out the DNA released by normal blood cells, reducing the "background noise” that can make early cancer signals difficult to detect.

Also read: Studying Live Cancer Cells Could Transform Drug Discovery; Researchers Turn Cell Biology Into ‘Live Cinema’

What Are The Study's Findings?

The researchers tested MethylScan using blood samples from 1,061 people, including patients with liver, lung, ovarian and stomach cancers, people with liver diseases and healthy participants.

At 98% specificity, the test detected about 63% of cancers across all stages. For early-stage cancers, its sensitivity was around 55%.

The test also showed promise in identifying where an abnormal signal originated. This could help as a positive blood test would still need to be followed by imaging or other diagnostic tests.

“Being able to trace signals back to their source is important because a positive blood test needs to be followed by imaging or other diagnostic procedures directed at the right organ,” Li said.

Also read: Tudriqev: US FDA Approves Replimune's Skin Cancer Drug After Rejecting It Twice

Early Cancer Detection Is Key

“Early detection is crucial,” said Dr Jasmine Zhou, the study’s senior author. “Survival rates are far higher when cancers are caught before they spread.”

The findings are promising, but larger trials will be needed to establish whether such tests can reliably detect cancers in people who have no symptoms.

Also read: Following A Western Diet? Changes In Your Gut Bacteria Could Increase Colon Cancer Risk

More Developments In The Field

The findings come as another multi-cancer test, Galleri, is designed to detect signals from more than 50 cancers from a single blood sample.

Reuters reported this month that the US FDA plans to convene an advisory panel in September to review its application for approval.

But experts continue to stress that these tests are not replacements for established screening, such as mammograms or colonoscopies.