Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.
Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.
Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.
If left untreated, TTTS can have devastating consequences. Medical research indicates that:
TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.
Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.
Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.
Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:
Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.
Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.
Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.
According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.
When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.
Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.
Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."
Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.
Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.
The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.
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There is no case of Ebola reported in India, said the government today, while stepping up surveillance in the country at key places such as airports and seaports.
The government has also "initiated precautionary public health measures", following the declaration of a Public Health Emergency of International Concern (PHEIC) by the World Health Organization (WHO).
A senior official in the Ministry of Health clarified that "there is no reported case of Ebola in India and the current risk to the country remains minimal".
However, India is closely monitoring the outbreak that has so far 336 suspected cases, including 88 deaths, in DR Congo; and
2 confirmed cases, and 1 death in Uganda.
"Senior officials of the Ministry, including officials from the National Centre for Disease Control (NCDC), Integrated Disease Surveillance Programme (IDSP), ICMR, and other concerned divisions, have reviewed the evolving situation and initiated precautionary public health measures," said the Ministry.
Key preparedness measures include:
"India’s public health system remains vigilant and fully prepared to respond to any emerging situation,” it said, adding that “citizens are advised to follow official updates issued by the Ministry of Health & Family Welfare and WHO”.
The official asserted that India continues to maintain close coordination with international health authorities and will take all necessary measures to safeguard public health.
On May 17, the WHO declared the Ebola outbreak in Central Africa a "public health emergency of international concern."
According to the Africa CDC, the outbreak is caused by a rare strain of the Bundibugyo virus, for which there is no vaccine available currently.
Bundibugyo virus disease is a rare and deadly illness that has caused outbreaks in several African countries in the past. It is different from other known ebolaviruses such as the Zaire ebolavirus and the Sudan ebolavirus.
The Bundibugyo virus spreads through contact with the blood or bodily fluids of a person infected with or who has died from the rare Ebola strain.
It can also spread through contact with contaminated objects such as clothing, bedding, needles, and medical equipment, or through contact with infected animals such as bats and nonhuman primates.
Historically, Bundibugyo virus outbreaks have recorded fatality rates ranging from 25 per cent to 50 per cent.
Symptoms To Watch For
Symptoms of Bundibugyo virus disease are similar to other forms of Ebola and include:
Prof Trudie Lang from the University of Oxford also described dealing with Bundibugyo as “one of the most significant concerns” in the current outbreak, the BBC reported.
Symptoms are believed to appear between two and 21 days after infection.
With no approved drugs specifically targeting the Bundibugyo virus, treatment currently depends on supportive care, including managing pain, treating secondary infections, maintaining fluids, and ensuring adequate nutrition. Early medical care improves survival chances.
Credit: iStock
The Democratic Republic of Congo is currently facing its 17th outbreak of the Ebola virus. While scientists have identified the outbreak as being caused by the rare Bundibugyo strain, a major concern is that there is currently no approved treatment or vaccine specifically targeting it.
Although highly effective vaccines such as ERVEBO exist, they are designed specifically for the Zaire strain of Ebola and do not protect against other strains like Sudan or Bundibugyo.
Now, a team of scientists at the Université de Montréal (UdeM) in Canada has identified a new family of natural molecules with strong antiviral activity, particularly against the Ebola virus.
Previously, in 2016 and again in 2020, researchers at the university’s Montreal Clinical Research Institute (IRCM) demonstrated that a plant extract rich in isoquercitrin — a flavonoid found in many plants — showed strong antiviral activity in laboratory studies.
However, the exact source of the effect remained unclear.
Researchers, including scientists from the University of Chicago, used advanced analytical methods and a rigorous bioassay-guided approach to determine that the antiviral activity did not originate from isoquercitrin itself, but rather from two previously unknown triterpenoid compounds.
Though present at only 0.4 per cent of the analyzed extract, these newly identified molecules — named dicitriosides — proved to be up to 25 times more active than the original extract against the Ebola virus under experimental conditions.
The compounds were also found to be effective against SARS-CoV-2, the virus responsible for the COVID-19 pandemic. Researchers noted that the molecules demonstrated antiviral efficacy at pharmacologically achievable concentrations.
“This discovery illustrates how compounds present in vanishingly small amounts in nature can have major therapeutic potential,” said Majambu Mbikay from the IRCM. “It also underscores the importance of carefully examining the true composition of natural products used in biomedical research.”
The scientists noted in the study that even though the findings are "still at the preclinical stage, it opens promising avenues for the discovery of new broad-spectrum antivirals derived from natural products”.
“No one knows when the next pandemic will occur, but one thing is certain: we must be prepared,” said Michel Chrétien, medical professor at UdeM. “These results demonstrate the importance of long-term fundamental research and international collaboration in anticipating the public-health challenges of the future.”
On May 17, the World Health Organization declared it a "public health emergency of international concern." The outbreak has also spread to Uganda.
According to the Africa CDC, the outbreak is caused by a rare strain of the Bundibugyo virus, for which there is no vaccine available currently.
Bundibugyo virus disease is a rare and deadly illness that has caused outbreaks in several African countries in the past. It is different from other known ebolaviruses such as the Zaire ebolavirus and the Sudan ebolavirus.
As per the US CDC, as of May 17, there are reports of 10 confirmed cases and 336 suspected cases, including 88 deaths, in DRC.
Uganda has reported 2 confirmed cases, including 1 death, among people who travelled from DRC. No further spread has been reported. These numbers are likely to increase as the outbreak evolves.
Credit: Instagram/CNN
After Eric Dane, another Grey’s Anatomy star, Russell Andrews has revealed that he has been diagnosed with amyotrophic lateral sclerosis (ALS).
The 64-year-old actor shared that he was diagnosed with the fatal disease in 2025, CNN reported.
“I am a person living with ALS,” said Andrews, known for his roles in Straight Outta Compton and Better Call Saul, alongside his fiancée, Erica Tazel.
“I was diagnosed in the late fall of last year,” he added.
ALS currently has no cure, and people diagnosed with the disease typically live three to five years after diagnosis, according to the Muscular Dystrophy Association.
However, some patients may survive for decades, like in the case of Stephen Hawking, who survived almost 40 years with a disease that usually kills people 14 months after diagnosis. Diagnosed at the age of 21, the noted astrophysicist and cosmologist lived until the age of 76.
Andrews’ co-star Eric Dane, who died earlier this year in February at the age of 53, also suffered from ALS. He died around 10 months after publicly revealing his ALS diagnosis.
Andrews shared that his initial symptoms included occasional “twitches,” which he first believed were caused by “pinched nerves” in his neck.
Soon after, “I was not able to do things that I normally do,” he said, adding, “I was dropping cups and glasses at night. It felt like things were running up and down my arm at different times, and it was the nerves.”
Andrews also revealed that he lost health insurance during the industry shutdown caused by the strikes, delaying his diagnosis because he was unable to undergo medical evaluations.
Once he regained insurance coverage, doctors quickly referred him to a neurologist, eventually leading to the ALS diagnosis. “Within 15 minutes, the primary care physician said she would like me to see a neurologist,” Andrews said.
What Is ALS?
Read More: Ebola Bundibugyo Strain: All You Should Know About The Rare Virus
Also known as Lou Gehrig's disease, ALS targets motor neurons, nerve cells in the brain and spinal cord responsible for voluntary muscle movement. When these neurons degenerate and die, the brain can no longer communicate with muscles, leading to muscle weakness, paralysis, and eventually respiratory failure.
Most individuals with ALS retain their cognitive function, but lose the ability to walk, speak, eat, and breathe without assistance. The disease progresses over time, with most patients surviving between two and five years following diagnosis.
ALS presents in unique ways from person to person. It can begin in the limbs (limb-onset) or in muscles related to speaking and swallowing (bulbar-onset). While no cure currently exists, treatment advancements have offered hope for improved quality of life and extended survival.
ALS can affect anyone, though it is most commonly diagnosed between the ages of 40 and 70. According to the CDC, around 5,000 new cases are diagnosed annually in the United States, with about 30,000 people living with the disease at any given time.
Symptoms of ALS can vary widely but often begin with muscle weakness, cramps, twitching, or difficulty with speech or swallowing. As the disease progresses, individuals may experience:
What Leads To ALS?
Though the exact cause of ALS remains unknown, genetic factors play a key role in some cases. Mutations in genes such as SOD1, C9orf72, FUS, and TARDBP are linked to the disease. Environmental triggers, like toxin exposure, viral infections, and intense physical activity, are also being studied.
ALS is diagnosed by ruling out other conditions through clinical evaluation, EMG tests, genetic screening, and imaging such as MRI. Early diagnosis is essential to access therapies and plan care.
There is no cure for ALS yet, but treatments like riluzole, edaravone, and tofersen (for those with SOD1 mutations) can slow progression.
Promising research areas include gene therapy, RNA-targeted treatments, biomarkers like Neurofilament Light Chain, and artificial intelligence for diagnosis and personalized care.
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