Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.
Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.
Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.
If left untreated, TTTS can have devastating consequences. Medical research indicates that:
TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.
Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.
Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.
Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:
Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.
Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.
Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.
According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.
When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.
Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.
Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."
Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.
Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.
The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.
Credit: AI generated image
Sexually transmitted infections (STIs) such as gonorrhea and syphilis have hit record levels in Europe in over a decade, according to new data from the European Centre for Disease Prevention and Control (ECDC).
As per the agency’s latest Annual Epidemiological Reports, there has been a sharp surge in bacterial STIs across Europe. It showed that the notifications of gonorrhea and syphilis, alongside congenital syphilis in 2024, reached their highest levels in over a decade, reflecting sustained transmission across multiple countries.
The ECDC blamed the "widening gaps in testing and prevention” behind the spike in STIs. It also called for urgent targeted action to prevent further spread, including among women of reproductive age.
The data for 2024 show that:
Bruno Ciancio, Head of Unit, Directly Transmitted and Vaccine-Preventable Diseases, said that left untreated, “these infections can cause severe complications, such as chronic pain and infertility and, in the case of syphilis, problems with the heart or nervous system”.
“Most distressingly, between 2023 and 2024, we have seen a near doubling of congenital syphilis, where infections pass directly to newborns, leading to potentially lifelong complications,” Ciancio added.
Transmission trends vary significantly across different population groups, the ECDC said.
Men who have sex with men remain the most disproportionately affected group, with the steepest long-term increases in gonorrhea and syphilis.
Among heterosexual populations, syphilis is rising, particularly among women of reproductive age, the consequences of which are a near doubling of congenital syphilis cases from 78 in 2023 to 140 in 2024 across 14 countries reporting data.
Reversing increasing trends in STI cases requires accessible prevention services, easier access to testing, faster treatment, and stronger partner notification to stop onward transmission.
The ECDC urged public health authorities to urgently update national STI strategies and strengthen surveillance systems to better monitor the impact of prevention efforts.
“Protecting your sexual health remains straightforward. Use condoms with new or multiple partners, and get tested if you have symptoms, such as pain, discharge, or an ulcer,” Ciancio said.
In the wake of increasing gonorrhea cases, the UK in 2025 rolled out a new vaccine. The vaccine, available at sexual health clinics across England, is being offered to people who are at the highest risk of getting gonorrhea.
This includes gay and bisexual men who have recently had multiple sexual partners and another bacterial STI within the last year. This new program is expected to protect thousands of people and save the NHS over £7.9 million in the next decade.
Gonorrhea is also increasing in the US, with the 2025 data from the Centers for Disease Control and Prevention showing that reported cases of gonorrhea, chlamydia, and syphilis have climbed by nearly 90 per cent since 2004. In 2023 alone, the country recorded more than 2.4 million cases of sexually transmitted infections.
The United States Food and Drug Administration (FDA) in December last year approved two new oral antibiotics to treat gonorrhea: Zoliflodacin and Gepotidacin. These approvals represent the first entirely new gonorrhea treatments in more than three decades.
Retatrutide has not yet received FDA approval. (Photo credit: AI generated)
Retatrutide, Eli Lilly’s new weight-loss drug, is in the final stages of its clinical trial, and the results seem very promising, the drugmaker said on Thursday. In a news release, they disclosed that the brand-new drug helped people lose up to 30 per cent of their body weight, which is about 85 pounds. The results are on a par with bariatric surgery, which helps people shed approximately 25 to 35 per cent of their total body weight within one to two years. Doctors say that this is the largest weight loss ever witnessed in a medical trial. While Lilly has not yet filed for approval from the Food and Drug Administration, the pharma giant says that it expects to file this year.
Retatrutide is similar to drugs like Zepbound and Wegovy that mimic the GLP-1 hormone. Retatrutide, however, along with GLP-1, mimics glucagon as well, thereby working like a triple agonist. This is unlike Zepbound, which is a double agonist. Researchers said that they have witnessed the impact of semaglutide and tirzepatide. However, Retatrutide's results went beyond the current weight-loss drugs on the market.
Dr Shauna Levy, medical director of the Tulane Weight Loss Center, explained that the current GLP-1s are not good enough to induce weight loss in people dealing with severe obesity and those who have a BMI of 35. Bariatric surgery can provide the same, but it seems that Retatrutide will be far more effective for people living with a high BMI who are trying to achieve a healthy weight.
Read more: Meet Retatrutide: The Unapproved Cousin Of Ozempic That Supports Weight Loss Differently
Retatrutide was in the third phase of its trials involving 2,300 obese or overweight participants. While the full results have not yet been released in a medical journal, participants who took the highest dose of the drug lost 28 per cent of their body weight, approximately 70 pounds. Furthermore, nearly half of the participants lost over 30 per cent of their body weight. The trial continued for 80 weeks, and a small group of severely obese patients took the drug for 104 weeks and lost about 85 pounds on average. Alternatively, patients who took high doses of Zepbound lost around 21 per cent of their body weight in 72 weeks. Wegovy users lost about 15 per cent of their weight in 68 weeks.
On the downside, there were some side effects too. Retatrutide users experienced the following side effects:
These have, however, been seen with GLP-1 drugs.
Retatrutide might be the next big weight-loss drug set to hit the market soon. It aims to maximise weight-loss results with fewer side effects for users. If approved, it could be helpful for patients who are struggling to lose weight on the current versions of GLP-1 drugs.
Credit: AI generated image
Amid rising cases of the Ebola virus in the Democratic Republic of Congo and Uganda, India and the US have stepped up airport screening.
The latest outbreak, caused by the Bundibugyo Ebola virus, has so far affected nearly 600 people and has caused 139 suspected deaths, as per the latest update by the World Health Organization (WHO). The global health agency has also determined that the deadly outbreak is a “Public Health Emergency of International Concern (PHEIC)”.
India today issued a health advisory for passengers arriving from or transiting through Ebola-affected nations. Passengers with symptoms or exposure history should immediately report to the airport health authorities before immigration clearance.
The advisory, issued by the Directorate General of Health Services (DGHS), specifically mentions travelers coming from the Democratic Republic of Congo, Uganda, and South Sudan, all of which have been categorized as "high-risk countries" by the WHO.
The advisory is displayed at the Delhi airport by the Airport Health Organization (APHO). It advises passengers to watch out for symptoms such as:
It also asks travelers who had direct contact with blood or body fluids of a suspected or confirmed Ebola patient to immediately report to the airport health officer or the health desk.
According to the APHO, any traveler developing symptoms within 21 days of arrival should seek immediate medical care and inform authorities about their travel history.
On Wednesday, India’s Health Secretary Punya Salila Srivastava chaired a high-level review meeting with health secretaries of all states and Union territories to assess preparedness and response measures for Ebola.
Officials clarified that “no case of Ebola has been detected in India so far”.
However, after the WHO declared Ebola a Public Health Emergency, the Indian government has proactively strengthened surveillance and preparedness measures across the country as an abundant precaution, official sources had said. During the meeting, states and Union territories were advised to ensure readiness at all levels.
The 2026 India-Africa Forum Summit, scheduled for May 28 to 31, was also postponed due to the "evolving health situation in parts of Africa", India's Ministry of External Affairs announced today.
The decision was made in recognition of “the importance of ensuring the full participation and engagement of African leaders and stakeholders, and mindful of the emerging public health situation on the continent", said a joint statement issued by the Indian Ministry of External Affairs and the African Union.
Meanwhile, the Centers for Disease Control and Prevention (CDC) has also been enhancing public health screening and traveler monitoring amid a growing Ebola outbreak, and non-US passport holders face entry restrictions if they have been to Uganda, the Democratic Republic of Congo, or South Sudan in the previous 21 days.
“To the American public, the risk to the United States remains low,” said Satish Pillai. “Travelers to the region should avoid contact with sick people, report symptoms immediately, and follow our travel guidance.”
A US missionary doctor infected with the Ebola virus while treating patients in DR Congo has been admitted to Charité hospital in Berlin. The patient was flown to Berlin on a special medical aircraft and then transported to the hospital in a specially designed vehicle escorted by police. The aircraft also carried six other people who had contact with the infected man.
Tedros Adhanom Ghebreyesus said he was “deeply concerned about the scale and speed of the epidemic”. He noted that the numbers are expected to rise given the time taken to detect the virus.
The WHO says it could take up to nine months before a vaccine against this particular species of Ebola is ready.
Two possible "candidate vaccines" against the Bundibugyo species are being developed, but neither has gone through clinical trials yet, WHO advisor Dr. Vasee Moorthy said, according to the BBC.
Speaking to journalists in Geneva, Tedros said 51 cases have been confirmed in the Democratic Republic of Congo — where the first case was reported — and two in neighboring Uganda.
© 2024 Bennett, Coleman & Company Limited