Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.

Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.

Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.

Potential Risks of TTTS

If left untreated, TTTS can have devastating consequences. Medical research indicates that:

• 90% of the cases of untreated TTTS lead to loss of one or both twins.
• Despite treatment, only a 70% survival rate for both twins is assured.
• Severe forms can result in preterm labor, cardiac failure in the recipient twin, and organ failure in the donor twin.
• Complications in long-term survivors include neurological damage and developmental delay in surviving infants.

TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.

Why Identical Twin Pregnancies Are More Complicated

Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.

Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.

Other Twin Pregnancy Health Risks

Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:

1. Premature Birth

Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.

2. Gestational Hypertension and Preeclampsia

Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.

3. Anemia

Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.

4. Birth Defects

According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.

5. Amniotic Fluid Imbalances

When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.

6. Postpartum Hemorrhage

Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.

Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."

Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.

Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.

The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.

Singapore is seeing a significant rise in COVID-19 cases, driven by the NB.1.8.1 variant from the Omicron family, nicknamed “Nimbus”.

According to a statement from the Communicable Diseases Agency, the number of COVID cases in Singapore rose to 12,700 in the week of May 10 to May 16, compared with 8,000 in the previous week.

The country is also seeing a rise in the number of daily COVID hospitalizations — from 56 to 73 during the same period, with one case in the intensive care unit daily on average, the CDA said.

NB.1.8.1 Variant Driving COVID Surge: Should People Be Worried?

The NB.1.8.1 variant is currently the dominant strain circulating in Singapore and accounts for more than half of locally sequenced cases.

The CDA noted that people at extremes of age, such as those aged 60 years and above, including those staying in aged care facilities, and medically vulnerable people aged six months and above, are at increased risk of severe COVID infection and should stay updated with vaccinations.

Calling the increase a “periodic wave” of COVID that “is expected throughout the year”, the agency said it is monitoring the spike.

“There is no indication that the variants circulating locally are more transmissible or cause more severe disease compared with previously circulating variants,” it added.

The CDA noted that the surge in cases may be due to waning population immunity, and stated that the currently available vaccine in the country continues to be effective for protection against this variant..

Also read: Child Mortality Rates In US Saw A Massive 6.6% Rise In Just 3 Years, Study Finds

All About The NB.1.8.1 Variant

NB.1.8.1 was first detected in January 2025. It is a “recombinant” variant, meaning it formed when two or more older variants mixed their genetic material.

On May 23, 2025, the World Health Organization (WHO) classified NB.1.8.1 as a “Variant Under Monitoring” (VUM). Scientists have identified changes in the virus that could affect how it spreads or infects people, although evidence is still evolving.

Previous laboratory studies also suggest the variant binds more tightly to human cells, indicating it may infect people more effectively than earlier variants.

Symptoms Linked To NB.1.8.1

People infected with NB.1.8.1 commonly report:

• Sore throat
• Cough
• Fever
• Muscle aches
• Stuffy or runny nose

Some patients also experience:

• Nausea
• Diarrhoea
• Fatigue
• Mild cough
• Nasal congestion

One unusual symptom linked to the variant is a severe “razor blade” sore throat, where people report sharp pain while swallowing food or beverages.

Read More: Europe Sees Record Surge In Gonorrhea, Syphilis Cases In Over A Decade: ECDC

How To Protect Yourself From Severe COVID-19

Vaccination remains the best protection against severe illness, especially for:

• Older adults
• Immunocompromised individuals
• People with underlying medical conditions
• Medically vulnerable individuals aged six months and above

Other Safety Measures

Authorities advised the public to continue basic preventive practices such as:

• Washing hands regularly
• Covering the nose and mouth while coughing or sneezing
• Wearing masks when symptomatic
• Avoiding unnecessary social interactions when unwell.

During the hot days of the year, amid a severe heatwave, it is only natural to feel irritable and anxious. But according to psychologists, some simple household chores will not just give you a sense of calm but will also work like meditation. Experts have found that manual chores like clearing away clutter, sweeping, and mopping prevent the mind from wandering while giving a concrete sense of accomplishment. Psychologists say that the process of cleaning is meditative and calming.

Experts and Zen monks often say that before enlightenment, one must carry water and chop wood. And even after enlightenment, the same process must be repeated. Repetitive activities like these can regulate the nervous system, as these acts are structured, predictable, and give a sense of completion at the end.

How does mopping help?

Zen monks and psychologists recommend mopping the floor, as this activity gives a sense of grounding and control. Additionally, one can immediately see the results of one's work, which is more satisfying than cognitive and emotional tasks that have slow results. "Unsui" monks spend most of their time tidying and cleaning. In A Monk's Guide to a Clean House and Mind, a monk wrote that they sweep dust to remove worldly desires and scrub dirt to free themselves from attachment. This time spent cleaning everything carefully, they say, is extremely fulfilling.

The mental health benefits of cleaning

Psychologists say that people who dread cleaning or find it daunting can engage in the activity to improve focus rather than stress about a to-do list. People who see cleaning as drudgery often feel that the shift is less about forcing oneself to enjoy it than about changing the way one engages with the activity. But the key here is not to rush through the process — experts say that it is imperative to pay attention to the rhythm of the physical movement or to things like water temperature.

When slowed down, it helps one focus on the sensory aspects, and it can start to function like a mindfulness exercise. Cleaning is an opportunity to free the mind and care for oneself and the world. For monks, cleaning is not just about fixing a room; it is a way to expand oneself and nurture one's relationship with the world. Therefore, instead of looking for a perfect result, it is important to embrace incompletion without anxiety.

When one feels overwhelmed, it is not about the task but about what the task represents. This could be self-judgement, time pressure, or anxiety, for instance. Breaking a task down into small and defined actions can reduce barriers. Therefore, instead of getting engrossed in the activity, one must try to break the task down into smaller and defined actions that reduce barriers. Start by choosing one room or surface to clean. Start with baby steps and then ease into the process. This awareness will give you a sense of peace similar to what one finds in temples.

The Union Ministry of Health and Family Welfare today notified the inclusion of the drug “Pregabalin” under Schedule H1 of the Drugs Rules, 1945, to strictly regulate the painkiller amid rising concerns over its misuse and abuse, particularly among youth.

Pregabalin, sold under the brand names Axalid and Lyrica, is a prescription medication used to treat epilepsy, neuropathic (nerve) pain, fibromyalgia, and generalized anxiety disorder. It was earlier regulated under Schedule H.

The ministry noted that the drug has reportedly been misused for its sedative, euphoric, and dissociative effects. Authorities have reported seizures of illegally stocked and unauthorized sale of Pregabalin from parts of the country.

Thus, the move to add it to Schedule H1 aims to:

• Curb easy access
• Enhance prescription monitoring
• Strengthen supply chain accountability
• Safeguard public health

In a gazette notification, the ministry said Pregabalin can now be sold only after a registered medical practitioner’s prescription.

The revised classification mandates that:

• Retailers must maintain a separate register recording details of prescriptions and sales
• Manufacturers shall prominently display the prescribed “Schedule H1 Drug Warning” label on product packaging
• Violations and non-compliance will attract penal action under the Drugs and Cosmetics Act, 1940, and Rules thereunder

All stakeholders, including manufacturers, distributors, wholesalers, retailers, and pharmacists, are advised to ensure strict compliance with the provisions of the notification.

Also read: India Cracks Down On Injectable Cosmetic Procedures In Beauty Clinics

Can Pregabalin Cause Heart Failure?

A 2025 study led by researchers at Columbia University Irving Medical Center linked Pregabalin with a surprisingly large increase in the risk of heart failure among older patients with known heart disease.

The study found that Pregabalin was associated with a 48 per cent higher risk of developing heart failure.

For patients with an existing history of heart disease, the risk jumped to 85 per cent. In absolute terms, the researchers estimated around six additional cases of heart failure per 1,000 people taking Pregabalin each year, compared to those not on the drug.

What Should Patients Do?

Like all medicines, Pregabalin carries side effects. Common ones include headaches, nausea, diarrhoea, blurred vision, and memory issues. Rarely, it can trigger a life-threatening allergic reaction called anaphylaxis.

If you take Pregabalin, do not stop it suddenly. Stopping abruptly can cause withdrawal-like symptoms. Instead, book an appointment with your GP or specialist to discuss the risks and benefits in your specific case.

If you have a history of heart disease, a heart condition, or new symptoms such as increased breathlessness, persistent swelling, or faintness, mention them promptly.

Pregabalin helps many people with otherwise disabling nerve pain, but like any tool, it must be used with care and attention to context. For older adults and those with heart disease, a conversation with a clinician could be the difference between control and complication.

Earlier this week, the Central Drugs Standard Control Organisation tightened rules around cosmetic use, amid growing concerns that injectable aesthetic procedures are gaining popularity as “cosmetic” treatments in beauty clinics and wellness centers across the country.

In a new public notice issued this week, the CDSCO stated that cosmetic products that come in injectable form do not fall under the definition of cosmetics under the law. It said that such products are not permitted for use by consumers, professionals, or aesthetic clinics.