Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.
Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.
Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.
If left untreated, TTTS can have devastating consequences. Medical research indicates that:
TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.
Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.
Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.
Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:
Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.
Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.
Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.
According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.
When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.
Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.
Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."
Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.
Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.
The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.
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Amid concerns over the MMR vaccine and falling childhood vaccination rates in the US, another child has died with measles.
The death was confirmed by Lancaster County Coroner Stephen Diamantoni, who said his office was investigating the case. He said the child died “a few weeks ago” but could not confirm whether it was the death Pennsylvania Gov. Josh Shapiro referred to last week.
“We just want to cast as wide a net as possible and identify any deaths that may have occurred in individuals who had measles,” Diamantoni said.
It remains unclear whether this is the second or third measles-associated death reported in the US this year.
In late August, Pennsylvania reported two measles-associated deaths in 2026, both involving unvaccinated individuals. One was reportedly an infant, while details about the second person have not been released.
The deaths are the first measles-related deaths reported in Pennsylvania in 35 years, according to the state Department of Health.
The infant’s death has been disputed. Lancaster County Coroner said the newborn tested positive for measles but died shortly after birth from a lacerated spleen. Measles antibodies were found during postmortem testing.
“The newborn had measles” but did not “die of measles,” Parsons said, citing the coroner.
The CDC has not included the two Pennsylvania deaths in its national measles count while it reviews additional information about the circumstances and causes of death.
According to the CDC, available information does not establish whether measles caused or contributed to the deaths or whether the individuals died from other causes while infected with measles.
The Department of Health and Human Services said the deaths had not been confirmed based on the information available to the CDC.
Pennsylvania, however, maintains that it followed the standard process and provided the CDC with the required epidemiological data.
The state calls the deaths “measles-associated,” meaning there is laboratory or epidemiological evidence of measles, even if the virus is not established as the immediate cause of death.
The US CDC has 2,903 confirmed measles cases in the US in 2026, as of August 27, 2026, the highest number in 35 years.
The cases are spiraling amid anti-vaccine stance promoted by the Trump-led US government and HHS Secretary RFK Jr.
More recently, Trump also announced a split of the MMR vaccine.
Measles has been considered eliminated in the US since 2000, but the Pan American Health Organization is expected to decide in November whether the US has lost its elimination status.
Measles is one of the most contagious infectious diseases. An infected person can spread the virus to around nine out of 10 unvaccinated people exposed to it.
Most people recover, but measles can cause serious complications, including pneumonia, brain inflammation and death.
Infants, pregnant women and people with weakened immune systems are particularly vulnerable.
Early measles symptoms can resemble a common cold and include:
A distinctive sign of measles is the appearance of tiny white spots, called Koplik spots, inside the mouth. These spots typically develop two to three days after the initial symptoms begin. Their presence is an important diagnostic clue and often appears before the characteristic measles rash.
A rash appears three to five days after the initial symptoms. It usually starts as flat, red spots on the face, near the hairline, and then spreads downward to the neck, trunk, arms, legs and feet.
The spots can sometimes be slightly raised and may merge. When the rash appears, the fever may also increase significantly.
Groups at higher risk of measles complications include:
Two doses of the MMR vaccine are key to preventing measles. Te first MMR dose is recommended at 12 to 15 months, followed by a second dose at 4 to 6 years.
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UK health officials have reported the breeding of an invasive mosquito species known to spread dengue, chikungunya and Zika viruses.
While this is the fourth time Aedes aegypti has been detected in the UK, it is the first time the species has been found breeding. The mosquitoes were found reproducing in homes in east London.
The UK Health Security Agency (UKHSA) said the risk to the public is low, with no evidence of human infections linked to these mosquitoes.
Officials believe the mosquitoes may have been accidentally imported in baggage, vehicles or plants. Measures to destroy larvae, along with surveillance and trapping, have been stepped up.
Mosquito-borne diseases kill more than one million people and infect up to 700 million each year.
While Aedes aegypti mosquitoes are usually found in tropical and subtropical climates, the current risk to the UK public remains low. The species is unlikely to survive long-term in the UK's colder temperatures.
UKHSA head of medical entomology Dr Jolyon Medlock said: "There is no evidence that these mosquitoes have caused human infections and importantly, to date, there is no evidence of the mosquitoes or larvae being detected in nearby public areas."
Dr César López-Camacho of the University of Oxford called the finding "important" but said it was not a reason for alarm.
Despite recent heatwaves, the overall UK climate remains too cold for Aedes aegypti to survive long-term, UKHSA said.
The mosquitoes were detected through the Mosquito Watch scheme, which monitors invasive species.
Medlock said the UK will continue to see invasive mosquitoes and that, as the climate warms, he expects more reports of them surviving.
Globally, dengue cases are increasing across the Western Pacific and Southeast Asia. These increases are fueled by climate change, globalisation and immunological naïveté, alongside the limited impact of existing control measures.
“While the current mosquitoes are unlikely to be infected, and so the risk to people will be low, their presence may indicate a regular summer event in future years. These mosquitoes will not survive the cooler weather of autumn or winter, but new introductions next year may lead to breeding again,” Martin Hibberd, Professor of Emerging Infectious Disease at the London School of Hygiene & Tropical Medicine (LSHTM), said.
He said the mosquitoes live in and around human habitations and are well adapted to city life, requiring the right climate conditions, which the UK is now experiencing more regularly.
Dr Robert Jones, Assistant Professor in the Department of Disease Control at LSHTM, said: “Even in outbreak situations, only a fraction of mosquitoes are infected, so the risk to the public from this finding is very low.”
He advised people to make gardens and outdoor spaces less suitable for mosquitoes by removing standing water.
“Mosquitoes can lay eggs in buckets, containers, plant pots and other places where water accumulates, so removing standing water can help limit the places available for them to lay eggs and reduce the likelihood of populations becoming established.”
To lower your risk of dengue and other mosquito-borne diseases:
Mosquito detection and eradication programs are key to preventing the problem from becoming a bigger public-health risk.
Credit: Massachusetts General Hospital
A pig kidney transplanted into a US man in 2025 functioned in his body for 271 days, marking the longest dialysis-free survival reported following a porcine kidney transplant, according to Harvard Medical School.
Tim Andrews, who was 66 at the time of the xenotransplantation, did not need dialysis for 271 days before receiving a human kidney from a deceased donor.
In January 2025, Andrews, received a genetically edited pig kidney, after being on dialysis for more than two years due to end-stage kidney disease. He became the fourth worldwide to receive a pig kidney.
Andrews received the genetically engineered pig kidney under an FDA Expanded Access Investigational New Drug application.
A team of doctors monitored him for kidney function, rejection, antibody development and potential pig-to-human infection, and found that the kidney began functioning immediately. An early episode of T-cell-mediated rejection resolved with treatment, and no pig pathogen transmission was detected, revealed the case published in the journal The Lancet.
After approximately six months, immunosuppression was reduced because of an infection. The xenotransplant subsequently developed microvascular injury and inflammation that progressed to organ failure.
In January this year Andrews received a deceased-donor human kidney, which showed immediate graft function, with no evidence of sensitization during follow-up.
The findings illustrate both the promise of xenotransplantation and the areas that still need improvement before pig organs can become a broader transplant option.
Importantly, the microvascular injury seen in the porcine kidney has implications for developing immunosuppressive strategies, donor genetic engineering and monitoring approaches in future clinical transplantation studies, the researchers said.
According to the latest data from the Global Observatory on Donation and Transplantation, a record 183,896 solid organ transplants were performed globally across 96 countries. This represents a 4% increase over 2024, primarily driven by an 11% rise in donations after circulatory death (DCD) and a 4% increase in living-donor transplants.
Despite this growth, a 90% unmet need remains a critical global issue as demand continues to rise, driven by chronic conditions such as diabetes and cardiovascular disease.
In the US alone, over 109,000 people remain on the national transplant waiting list, while an average of 12 people die every day waiting for a compatible match, according to HRSA Organ Donor Statistics.
India recorded a record 20,138 transplants, yet more than 89,000 patients are actively waitlisted, according to data from NOTTO. The deceased-donor rate remains critically low at 0.77 per million people, with deceased-donor organs accounting for only 18% of the country's total transplant pool.
“The organ shortage is the greatest crisis we have right now in transplantation,” said Leonardo Riella, associate professor of surgery at Mass General and medical director for kidney transplantation at Mass General Brigham.
“We know that the best treatment option for patients with end-stage kidney disease who have developed renal failure is transplantation, but we simply don’t have enough human organs to transplant in a timely manner.”
Andrews’ case therefore offers a potential way to help bridge this gap.
“Our vision is that xenotransplantation could help address this gap — initially as a bridge to get patients off dialysis while they wait for a human donor kidney, and potentially, as we establish long-term safety and durability, as a destination therapy in its own right,” Riella said.
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