Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.
Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.
Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.
If left untreated, TTTS can have devastating consequences. Medical research indicates that:
TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.
Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.
Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.
Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:
Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.
Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.
Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.
According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.
When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.
Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.
Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."
Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.
Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.
The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.
Credit: AI
The Ebola outbreak in the Democratic Republic of the Congo (DRC) has reached another concerning milestone. With a surging number of deaths and confirmed infections, the healthcare workers in the affected regions have threatened to declare a strike due to nonpayment of dues, making it challenging to contain a deadly and aggressive outbreak.
According to Reuters, the total confirmed number of deaths due to Bundibugyo Ebola has reached 600, with 1,759 confirmed infections as of July 9.
This comes amid protests demonstrated by healthcare workers in the affected regions, who have threatened to walk off the job due to months of unpaid wages and unsafe working conditions.
The outbreak initially affected Ituri, North Kivu and South Kivu provinces, but authorities are now investigating suspected cases in Tshopo province, including Kisangani, sparking concerns that new areas may be affected.
The outbreak, caused by the Bundibugyo species of the Ebola virus, has been spreading rapidly since it was declared on May 15.
Unlike the Zaire strain, there is currently no approved vaccine or specific treatment for Bundibugyo Ebola virus, making containment and treatment efforts particularly challenging. Currently, experimental therapies are being examined through ongoing clinical trials.
The worsening outbreak could be even more challenging to contain as the frontline healthcare workers, including treatment staff, laboratory personnel, and burial teams, have been protesting nonpayment of salaries, insufficient protective equipment, and difficult working conditions.
According to several reports, many workers say they have not been paid since the outbreak began nearly two months ago. While some have already stopped working, others have warned that a mass walkout could further weaken the country’s Ebola response.
The administrative disruption significantly threatens critical epidemic operations like patient care, lab testing, contact tracing, and safe burial procedures, all of which are essential for slowing transmission and effectively containing the outbreak.
The World Health Organization has repeatedly warned that the outbreak remains in an “expansion phase” due to several reasons, including overwhelmed treatment facilities, population movement, and delays in identifying and isolating infected individuals.
WHO also said that the treatment centers in some of the hardest-hit regions are operating near 90% capacity. Infection cases among healthcare workers are another concern that highlights the risks faced by frontline responders.
Misinformation about the disease has been rife in several Congolese communities. According to the Council on Foreign Relations, there have been reports that some local communities believe that the disease is a hoax or was brought into the country by Western aid workers who wanted to make a profit.
While Ebola is not a new disease, the current outbreak poses a significant threat because it is caused by a rare strain of the virus, Bundibugyo. The rarity of the strain has created scientific and emergency public health challenges, as there is currently no licensed vaccine to protect against the Bundibugyo Ebola virus.
Credit: iStock/Novo Nordisk
Danish pharmaceutical giant Novo Nordisk has launched Awiqli (insulin icodec) in India, introducing the world's first once-weekly basal insulin for adults with diabetes.
Individuals with Type 2 diabetes require daily insulin to manage their blood glucose when diet, exercise, and oral medications are no longer sufficient.
The daily basal insulin injections are typically taken once every 24 hours. But Awiqli is designed to provide background insulin support throughout the week, reducing the number of injections from 365 per year to 52, Novo said.
More than 101 million people in India are living with diabetes, while another 136 million have prediabetes, Novo said in a statement.
Insulin initiation in India is delayed by an average of 7-9 years, partly due to fear of injections, anticipated pain, and cost concerns, it said.
"We believe Awiqli will reduce the psychological and physical barriers to insulin initiation," Novo Nordisk India Managing Director Vikrant Shrotriya said.
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Awiqli (insulin icodec) is a long-acting basal insulin designed to help adults with diabetes maintain stable blood sugar levels with just one injection every week. It is administered using the Awiqli FlexTouch pen on the same day each week.
The treatment is intended to simplify insulin therapy, potentially improving treatment adherence among people who struggle with daily injections.
Earlier this year, the US Food and Drug Administration (FDA) approved Awiqli (insulin icodec-abae) 700 units/mL as the first and only once-weekly basal insulin for adults with type 2 diabetes. The therapy is indicated as an adjunct to diet and exercise to improve glycemic control.
The approval offers a new treatment option for patients seeking an alternative to daily basal insulin, allowing diabetes care to be tailored to different lifestyles and treatment preferences.
"Awiqli may address challenges associated with the frequency of daily basal injections by reducing them from seven to one per week. It is an important advancement for adults with type 2 diabetes who may benefit from an alternative treatment option," said Anna Windle, Group Vice President, Clinical Development, Medical & Regulatory Affairs at Novo Nordisk Inc.
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The therapy has now been launched in India. Awiqli has also received regulatory approval in the US, the European Union, and 13 other countries, with indications varying according to local regulatory approvals.
The approval is supported by Novo Nordisk's ONWARDS Phase 3a clinical program, which enrolled nearly 2,680 adults with uncontrolled type 2 diabetes across four randomized, active-controlled trials.
The studies compared once-weekly Awiqli with daily basal insulin and demonstrated effective reductions in HbA1c, a key measure of long-term blood sugar control. The overall safety profile was found to be consistent with existing daily basal insulin therapies.
Awiqli is prescribed for adults with diabetes and should be used exactly as directed by a healthcare professional.
Patients should inject the medicine once every week on the same day. The dosage should not be adjusted without medical advice, the company said.
Like other insulin therapies, Awiqli may cause side effects, including:
Patients are advised to monitor their blood sugar regularly and seek immediate medical attention if they experience symptoms of severe allergic reactions or persistent hypoglycemia.
Do not take Awiqli if you:
Credit: iStock
Global cancer cases could reach nearly 35 million a year by 2050, without urgent action to improve cancer prevention, early diagnosis and access to treatment, according to the World Health Organization (WHO) Global Status Report on Cancer 2026.
The report warns that cancer remains the world's second leading cause of death, claiming more than 26,000 lives every day and nearly 10 million annually.
The report, jointly released by the WHO and the International Agency for Research on Cancer (IARC), warned that major inequalities in cancer prevention, diagnosis, treatment and supportive care continue to leave millions of people without access to life-saving services.
It also noted that ageing populations, population growth and persistent health inequalities are driving the cancer cases.
"Cancer is a deeply personal disease that touches nearly all of us. But whether a person survives cancer should never depend on where they were born or what they earn," said WHO Director-General Dr Tedros Adhanom Ghebreyesus.
"The inequities documented in this report are not inevitable; they are the consequence of choices, and they can be reversed through stronger and unified action."
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The report highlights major disparities in cancer outcomes.
Beyond its health impact, cancer also creates significant economic and emotional challenges.
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The report shows that the burden of cancer varies significantly across regions.
Although home to only about 9% of the world's population, Europe accounts for:
Many African countries continue to experience comparatively lower cancer incidence but disproportionately higher mortality because of delayed diagnosis and limited access to treatment.
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According to the WHO report:
The report estimates that almost 40% of cancer cases worldwide are linked to preventable risk factors, including:
The WHO has urged governments, health organizations, researchers and the private sector to work together to strengthen cancer care through three broad priorities:
Better capabilities
Better protections
Better value
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