Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.

Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.

Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.

Potential Risks of TTTS

If left untreated, TTTS can have devastating consequences. Medical research indicates that:

• 90% of the cases of untreated TTTS lead to loss of one or both twins.
• Despite treatment, only a 70% survival rate for both twins is assured.
• Severe forms can result in preterm labor, cardiac failure in the recipient twin, and organ failure in the donor twin.
• Complications in long-term survivors include neurological damage and developmental delay in surviving infants.

TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.

Why Identical Twin Pregnancies Are More Complicated

Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.

Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.

Other Twin Pregnancy Health Risks

Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:

1. Premature Birth

Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.

2. Gestational Hypertension and Preeclampsia

Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.

3. Anemia

Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.

4. Birth Defects

According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.

5. Amniotic Fluid Imbalances

When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.

6. Postpartum Hemorrhage

Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.

Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."

Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.

Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.

The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.

Pakistan-made skin lightening creams that Indian regulators warned consumers against are still showing up on online marketplaces. This has raised concerns about how unauthorised cosmetics are reaching buyers despite regulatory restrictions.

The Central Drugs Standard Control Organisation (CDSCO) has issued a public health alert against Goree Beauty Cream and Chandni Whitening Cream, both produced in Pakistan.

The regulator said the creams were not registered for import into India and contained excessive heavy metals beyond specified limits, which could have toxic effects.

Some of the products listed on marketplaces including Amazon, Flipkart, Meesho, Tata 1mg and Snapdeal reportedly described the products as “Made in India”, while manufacturer or seller information was incomplete or obscured.

Why Are Mercury-Laced Face Creams Dangerous?

Also read: India’s Hidden Stillbirth Burden: Lancet Study Finds 2.2 Lakh Pregnancy Losses Missed By Current Reporting Method

The concern is particularly serious because mercury can be absorbed through the skin. Mercury is sometimes added illegally to skin-lightening products because it interferes with melanin production, producing a faster whitening effect. But the same process exposes users to a toxic heavy metal.

Dr. Surendra VHH, Senior Consultant - Dermatologist, Apollo Hospitals, Bangalore, spoke to HealthandMe about how long-term use of mercury-laced toxic cosmetics can cause harm.

He says, “The quick lightening effect may seem appealing, but it can come at a serious health cost. Mercury suppresses melanin production and may also cause rashes, skin thinning, sensitivity, and lasting pigmentation changes.”

Talking about the extreme side-effects of using these creams, he said that long-term exposure can allow mercury to accumulate in the body, particularly the kidneys. It has been associated with kidney damage, neurological problems and immune-system effects.

He says, “Mercury-laced skin-lightening creams are not harmless beauty products. Repeated use can expose the body to mercury, can get absorbed especially damaged unhealthy which may affect the kidneys and nervous system, causing symptoms such as headaches, weakness, numbness, tremors and changes in mood or memory. The risk is particularly concerning for pregnant women, breastfeeding mothers and children because of its potential impact on neurological development.”

Also read: MIT Student Exposed To One Of The World’s Deadliest Chemicals: Why Is Dimethylmercury Toxic Even In Tiny Amounts

Agreeing with Dr Surendra, Dr Ruben Bhasin Passi, Senior Consultant - Dermatology, CK Birla Hospital, Gurgaon, told also HealthandMe that mercury-infused cosmetics come at a long-term health cost.

Warning about the same, she explained, “Prolonged exposure may damage the skin’s natural protective barrier, cause persistent discolouration, and allow mercury to accumulate in the body, potentially affecting the kidneys and nervous system. No promise of lighter skin is worth exposing yourself to a substance that can silently compromise your health.”

A 2024 study published in Kidney International found a strong association between prolonged use of mercury-containing skin-lightening creams and membranous nephropathy, a kidney disorder in which the filtering units of the kidneys become damaged and leak excessive amounts of protein into urine.

The World Health Organization has also warned that mercury exposure can severely affect the kidneys, brain and nervous system, and says there is no known safe level of exposure to mercury.

Indian Regulator Issues Alert

CDSCO has advised consumers not to purchase or use Goree Beauty Cream, Chandni Whitening Cream or similarly named products.

The regulator has also reminded consumers that imported cosmetics must have the required registration and that legally marketed products should carry details like the manufacturer's information, manufacturing license, batch number, manufacturing and expiry dates and, for imported cosmetics, a registration number.

The warning comes after Maharashtra authorities separately banned Goree Beauty Cream following testing that found toxic mercury in the product. Officials had also received complaints involving users who developed kidney-related problems after prolonged use.

Cautioning the users, Dr Surendra said, “Consumers should be wary of products without a clear ingredient list, manufacturer details, batch information or regulatory information. Claims such as “instant whitening” or “herbal” do not automatically mean a product is safe. Anyone concerned about mercury exposure should stop using the product and consult a doctor, especially if symptoms such as tremors, swelling or changes in urination occur. Skin care should focus on healthy skin—not changing its natural colour through potentially harmful shortcuts.”

India’s burden of stillbirths may be larger than what existing official numbers suggest. A new study published in The Lancet Regional Health – Southeast Asia estimates that 565,900 babies were stillborn in India in 2023 when stillbirth is counted from 22 weeks of pregnancy onwards. That comes out to be roughly one stillbirth every minute.

But when the count is restricted to 28 weeks or later, the estimate falls to 347,300. That gap of nearly 220,000 stillbirths has become the focus of the study, casting a doubt on the current method of counting and reporting.

Researchers say India’s true burden of stillbirths is being underestimated as many earlier fetal deaths are being left out of the count.

Definition Of Stillbirth Gestational Age

Stillbirth does not have one universal gestational-age definition. The WHO’s ICD-11 definition uses 22 weeks of gestation or more, while India’s routine reporting and several international comparisons have traditionally focused on losses at 28 weeks or later.

Even though the difference may sound like a technical detail, it changes how many deaths are counted and how many get left out of the database.

The new study found that India's stillbirth rate was 25.9 per 1,000 births at 22 weeks or later, and 16.1 per 1,000 when only deaths at 28 weeks or later. In other words, using the latter threshold captured only part of the real picture.

Researchers also found that the burden was not evenly distributed. Stillbirth rates varied more than four-fold between states, from 9.3 per 1,000 births in Mizoram to 38.2 per 1,000 in Uttar Pradesh. Uttar Pradesh and Bihar together accounted for nearly half of India's total estimated stillbirths.

Also read: After Lindsay Clancy Trial, Massachusetts Pushes Stronger Postpartum Mental Health Screening

India’s Numbers May Be Missing More Than Babies

The researchers compared their estimates with India's Sample Registration System (SRS) and found substantial under-reporting. The national late-gestation stillbirth rate from SRS was 2.3 times lower than the GBD estimate.

Earlier research has also highlighted the same problem. An analysis comparing India's National Family Health Survey with SRS found that the NFHS stillbirth rate was 2.6 times higher than the SRS figure between 2016 and 2020.

Researchers have pointed to incomplete reporting, differences in gestational-age cut-offs and confusion between stillbirth and early neonatal death as possible reasons.

The latest Lancet analysis therefore argues that better surveillance is essential, particularly with routine reporting from 22 weeks onwards.

Also read: 22-Year-Old Frozen Embryo Produced A Healthy Baby: Does An Embryo Have An Expiry Date?

What Is Stillbirth?

Stillbirth is not caused by one single condition. Complications related to the placenta, fetal growth, maternal infections, hypertension, diabetes, congenital abnormalities and complications during pregnancy or labour can all contribute.

Maternal anaemia is another risk factor that has been receiving attention lately. A large Indian study published in August 2026, involving nearly 220,000 pregnancies across 10 cohorts, found that moderate and severe maternal anaemia were associated with a higher risk of stillbirth after 28 weeks. The findings are particularly relevant in India, where NFHS-5 data showed that about 52% of pregnant women were anaemic.

The study calls for stronger antenatal care, intrapartum monitoring, emergency obstetric services and strong healthcare systems, along with better data on the causes and risk factors behind stillbirth.

As study author Rakhi Dandona wrote while discussing the research: “every stillbirth deserves to be counted, understood, and learned from.”

India’s medical industry has backed Maharashtra Food and Drugs Administration (FDA) Commissioner Tukaram Mundhe’s concerns about the sharp gap between procurement prices and maximum retail prices (MRPs) of several medical devices and hospital consumables, with patients ultimately bearing the burden.

IV Set: At Rs 11.05, MRP Rs 325

In a post on social media platform X, Mundhe said the most expensive part of a hospital bill may never touch the hospital, but patients bear the brunt as they have the least information to evaluate, compare prices, or seek alternatives.

This is because “a patient admitted for care has no way of knowing whether the price on a medical consumable reflects its actual cost or a markup fixed long before it ever reached the ward," said the IAS officer, who has previously led several food safety enforcement measures in the country.

He flagged the information gap as a core public health issue.

He shared how a survey of hospital consumables in Maharashtra found an IV infusion set with a trade price of Rs 11.05 carrying a printed MRP of Rs 325, a markup of 2,841%. A syringe procured at Rs 6.75 carried an MRP of Rs 57.20, while a catheter procured at Rs 29.41 carried an MRP of Rs 310.

He noted that “the MRP is often fixed upstream by manufacturers and distributors, disconnected from the trade price by a wide, unexplained margin. The result is a system where the party bearing the cost has the least information to evaluate it”.

Also read: High Sugar, Salt Or Fat? India May Mandate Red Hexagon Labels On Food Packs

Experts Call For Scientific Costing

“Piecemeal assessment of pricing will not serve any purpose. Hospitals get reimbursed under CGHS and PMJAY for procedures at below operating cost. We do not look at that. It is time that we carry out a scientific costing exercise on delivery of healthcare,” Dr Girdhar Gyani, AHPI Director, told HealthandMe.

“Patients deserve fair prices, not 2,800% markups, and ethical manufacturers deserve a level playing field and a fair opportunity to provide affordable, fair-priced medical devices,” added Rajiv Nath, Forum Coordinator, Association of Indian Medical Device Industry (AiMeD).

Maharashtra FDA Flags Regulatory Gap

Mundhe also flagged the structural regulatory gap. He noted that “scheduled medicines are capped under the Drugs (Prices Control) Order, 2013. Most medical devices and consumables are not leaving both the pricing and the information around it almost entirely unmonitored”.

He called on the Department of Pharmaceuticals and the NPPA to “review” these findings and lay down “clear guidelines on the permissible gap between trade procurement price and declared MRP”.

“It's a step toward closing not just a pricing gap, but the information gap patients are left to bear alone”.

Industry Seeks Fair Pricing Policy

Welcoming the timely intervention by Mundhe, AiMeD said it has consistently cautioned that the current regulatory framework under the Drugs (Prices Control) Order, 2013 is inadequate for medical devices.

“Patients, who cannot bargain or choose devices, are left vulnerable to inflated MRPs, while ethical manufacturers and importers are forced to either play within a distorted system or exit the market. This situation penalises both consumers and responsible suppliers, eroding trust and competitiveness”, it said.

AiMeD has long advocated for a Fair Pricing Policy tailored to medical devices, with transparent trade-margin caps based on ex-factory or landed import prices. Such a system would ensure affordability for patients, encourage ethical competition and strengthen the “Make in India” vision.