Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.
Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.
Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.
If left untreated, TTTS can have devastating consequences. Medical research indicates that:
TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.
Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.
Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.
Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:
Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.
Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.
Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.
According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.
When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.
Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.
Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."
Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.
Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.
The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.
Credit: iStock
India must move beyond treating hemophilia—a genetic bleeding disorder—only after bleeding episodes and focus on preventing bleeding and its complications, health experts said at the UP-Hemophilia Conclave 2026.
Hemophilia is a rare bleeding disorder where blood does not clot properly, even for minor injuries. It is caused by an error in a specific gene on the X chromosome, leading to a deficiency or absence of clotting factors.
The country has the world's second-largest population of people with hemophilia, who experience spontaneous and traumatic bleeding due to low or very low levels of clotting factors.
The World Federation of Hemophilia (WFH) reported nearly 28,000 diagnosed and registered Persons with Hemophilia (PwH) in India as of 2026, including more than 24,000 with Hemophilia A. However, the estimated prevalence could be as high as 1,36,000, suggesting many cases may remain undiagnosed or misdiagnosed. In Uttar Pradesh, around 7,700 PwH are diagnosed, including approximately 5,500 with Hemophilia A.
Although India has expanded access to modern diagnosis and treatment, including gene therapy trials and non-factor therapies (NFTs) such as emicizumab, experts said preventive care needs to be strengthened.
Also read: Why India Must Shift Towards Prophylaxis Care For Hemophilia
Hemophilia patients should be able to lead normal lives and be managed like people with chronic conditions such as diabetes and hypertension, with regular replacement treatment to prevent complications, said Prof A. K. Tripathi, Clinical Hematologist and former Director, RMLIMS, Lucknow.
“At present, patients largely rely on reactive treatment, where therapy is given only after a bleeding episode. This approach is neither appropriate nor effective. They do not just need treatment when they bleed; they need treatment that prevents bleeding in the first place. The only way forward is to start prophylaxis,” he said.
Repeated joint bleeding can cause lasting damage, making it difficult to walk and, in severe cases, leaving patients chair-bound or bed-bound.
Regular replacement treatment, or prophylaxis, can protect joints and muscles and improve quality of life, said Dr S. P. Verma, Professor and Head, Department of Clinical Hematology, King George's Medical University (KGMU), Lucknow.
“Preventive treatment through regular replacement therapy (prophylaxis) has emerged as the global standard of care. This changing treatment landscape presents an opportunity to strengthen preventive care and improve long-term outcomes for patients,” said Dr Nita Radhakrishnan, Professor and HOD, Pediatric Hematology and Oncology, Post Graduate Institute of Child Health (PGICH), Noida.
Read More: Type 2 Diabetes Affects Men And Women Differently, New PLOS Study Finds
Vineet Manchanda, Secretary, Hemophilia Society, Lucknow, and Manoj, Hemophilia Federation of India (HFI) North and Agra Chapter, flagged that “Factor VIII, a clotting factor that can prevent bleeding in Hemophilia patients, is very expensive, and the government hospital’s supply is erratic, making availability a major issue".
They also stressed the importance of physiotherapy alongside newer therapies such as prophylaxis.
The experts also highlighted the financial burden of complications, including costly knee or hip replacement surgeries.
Access remains a major concern, with many patients travelling long distances for treatment. “Despite the resources, manpower and factors being invested, we are not achieving the desired results,” Prof Tripathi said.
Experts also called for better use of available budgets to identify and support patients who need treatment the most.
Organized under the aegis of the Uttar Pradesh Hematology Group (UPHG), the UP-Hemophilia Conclave 2026 was held in Lucknow under the theme ‘Uniting Care. Improving Lives.’ It brought together hematologists, physicians, researchers, pathologists, healthcare professionals from hemophilia treatment centers, policymakers and patient groups.
Credit: AI
Days after a rare cancer cluster in California's Ladera Ranch made headlines, another revelation has added to the mystery. An unusual number of children and young adults got diagnosed with Ewing sarcoma, a rare type of cancer.
According to Los Angeles Times, between 2013 and 2024, at least six cases of Ewing sarcoma surfaced, leaving the families of patients knee-deep in questions.
According to the American Cancer Society, the cancer is so rare that only 200 children and teenagers are diagnosed in the United States every year.
Just when the families of patients were looking for answers, another layer of mystery unraveled after a couple of 20-year-old handwritten notes emerged, signaling towards a probable cause behind the cancer cases.
The notes talk about an oil well at the site. According to The New York Post, the notes appear twice on the Department of Conservation permit, and state, "This well is not to be built over without further considerations."
State oil and gas supervisor William F Guerard Jr, acting state oil and gas supervisor Kenneth Henderson and deputy supervisor RK Baker signed the final report after the well was sealed on February 26, 2002.
The memos warning that no structures must be constructed above the well were reportedly written by engineer Floyd Leeson. They do not reveal why such a warning about the well was issued. Another note had an arrow pointing at the message, with the phrase: "Put on final letter."
According to Los Angeles Times, Henderson could not recall why such a warning was issued, although he believes the way the well was sealed might not be "up to the current standards." Meanwhile, the Department of Conservation said that the notes could have been a "clerical error."
Also read: Cancer Should Be Made Notifiable In India, Say Experts: Here’s Why
Symptoms can initially be easy to dismiss because they may resemble a sports injury or ordinary growing pains. They include persistent bone pain, swelling or a lump, unexplained fever, fatigue or a bone that breaks after relatively minor trauma can sometimes signal the disease.
The cancer can metastasize quickly, which is why persistent or unexplained symptoms need medical evaluation.
Also read: New Clinical Trial Shows Promise In Non-Surgical Treatment Of Early-Stage Rectal Cancer
Documents related to the abandonment of an old oil well reportedly contain a handwritten warning from about 20 years ago regarding the development of the site. This prompted fresh questions about what was known about the land before the modern community was built.
There are also concerns about possible pesticide and herbicide exposure, with residents previously urging authorities to investigate environmental factors.
However, none of these potential exposures have been shown to cause the Ewing sarcoma cases in Ladera Ranch. Even though doctors are concerned, they are of the opinion that environmental factors cannot be solely tied to Ewing sarcoma.
Credit: iStock
The US is battling one of its worst Cyclospora outbreaks in years, with tens of thousands of Americans affected. Despite the spread to nearly all states, the investigation into the source took significantly longer than expected.
Health Secretary RFK Jr claimed the outbreak was under control. However, the latest Centers for Disease Control and Prevention (CDC) data show more than 17,000 confirmed cyclosporiasis cases across 48 states and Washington, D.C., between May 1 and August 24. Another 11,844 cases may require further investigation.
Amid the outbreak and growing food safety concerns, the Trump administration is shuttering two of three US Department of Agriculture (USDA) research projects studying Cyclospora, Politico reported.
The two projects were defunded by Congress earlier this year. The third is due to move from Maryland to Iowa in the coming months as part of a broader USDA reorganisation.
Although the third project remains funded, all scientists working on Cyclospora have declined to relocate to Iowa, according to Politico, citing people familiar with the plans and internal documents.
The USDA has blamed Congress for eliminating funding for the two projects housed at the Beltsville Agricultural Research Center (BARC) outside Washington.
“None of the research has been disrupted, and research will continue without disruption,” a USDA spokesperson said, adding that Congress did not appropriate funds for the projects for fiscal year 2026.
The Agricultural Research Service is working with research leaders to ensure an orderly transition, the spokesperson said.
Also read: Mangoes Sold At Walmart Recalled In 4 US States Over Salmonella Risk
Scientists studying foodborne parasites, including Cyclospora, are retiring or leaving the USDA’s Agricultural Research Service rather than relocating or moving to other projects, the report said.
“We know so little, and I think that that’s been very frustrating to consumers,” said Kalmia Kniel, a University of Delaware professor who researches Cyclospora.
Without BARC, “no one can work very fast,” she said, citing the lack of research models and other tools needed to study the parasite.
Susan Mayne, an adjunct professor at the Yale School of Public Health, who ran the food-safety department of the Food and Drug Administration from 2015 to 2023, told CBS News that during President Trump's second term, the FDA has lost about 20% of its staff and the CDC 25%, according to the information provided.
The CDC’s team tracking food parasites has also fallen from 11 scientists to three.
Read More: From Dog Food To Fruit Bars: Over 10 Products Recalled In US Over Contamination
The Foodborne Diseases Active Surveillance Network (FoodNet), a collaboration among the CDC, FDA, USDA and 10 state health departments, tracked eight pathogens, including Cyclospora, for three decades.
Since July 1, 2025, reporting on pathogens other than Salmonella and E. coli has been optional. FoodNet now tracks only those two pathogens, meaning Cyclospora is no longer routinely monitored through the programme.
The US Preventive Services Task Force (USPSTF) has also been prevented from meeting since March 2025.
The panel was expected to issue recommendations this year on cognitive-decline screening and 13 other topics, The Guardian reported.
In addition, two panel chairs have been fired, while at least eight vacancies remain unfilled.
While Kennedy has called for stronger Alzheimer’s screening, he criticised the panel and accused the task force of being “lackadaisical and negligent for 20 years”, while saying the administration was making major investments in science to improve Alzheimer’s screening.
However, HHS spokesperson Emily Hilliard defended the department and said it remains committed to Alzheimer’s research.
© 2024 Bennett, Coleman & Company Limited