Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.

Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.

Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.

Potential Risks of TTTS

If left untreated, TTTS can have devastating consequences. Medical research indicates that:

• 90% of the cases of untreated TTTS lead to loss of one or both twins.
• Despite treatment, only a 70% survival rate for both twins is assured.
• Severe forms can result in preterm labor, cardiac failure in the recipient twin, and organ failure in the donor twin.
• Complications in long-term survivors include neurological damage and developmental delay in surviving infants.

TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.

Why Identical Twin Pregnancies Are More Complicated

Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.

Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.

Other Twin Pregnancy Health Risks

Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:

1. Premature Birth

Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.

2. Gestational Hypertension and Preeclampsia

Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.

3. Anemia

Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.

4. Birth Defects

According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.

5. Amniotic Fluid Imbalances

When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.

6. Postpartum Hemorrhage

Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.

Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."

Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.

Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.

The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.

Panic has gripped the residents of two villages in Rajasthan's Salumbar district, where five children have reportedly died within five days. The reason: an unknown disease characterized by a sudden onset of fever that worsens rapidly, and claims the lives of children within 24 hours.

According to officials, the children who died were between 2 and 4 years old, and all of them developed high fever, convulsions, and vomiting before their condition worsened rapidly.

Besides the five children who died, another 8 children are reportedly showing similar symptoms of the unknown disease.

The incident has been reported from Ghata and Lalpura villages in Lasadiya block.

The Disease Yet To Be Identified

The deaths have created fear among villagers, who submitted a memorandum to the SDM and health officials, seeking immediate action and identification of the disease.

District officials, along with a medical team, have reached the villages. The District Collector has ordered an inquiry. Medical teams are currently stationed in the villages, according to local media reports. Blood samples and other tests are being conducted to check for viral infection, brain fever, or any seasonal illness.

After preliminary treatment, five of the eight children newly affected with the mystery illness were referred from Lasadiya CHC to Udaipur District Hospital. Meanwhile, three children were referred to Salumbar District Hospital.

"Seventeen teams have been deployed in Lalpura and Ghata villages. Around 562 families live in this area," said Dr. Dinesh Rai Sapela, Additional District Collector.

Health teams are also conducting door-to-door screening, as well as collecting blood samples. These samples have been sent to RNT Medical College in Udaipur for testing.

“The exact cause behind the deaths is not yet known. It could be a viral infection or a seasonal disease, but confirmation will only come after test results,” said BCMO Dr Sintu Kumawat.

Meanwhile, Gayatri Rathore, Principal Secretary of the Medical and Health Department, stated that the Chief Medical and Health Officer of the Salumbar district has been instructed to form teams of health workers to ensure intensive screening of children exhibiting fever symptoms—not only in the affected villages but also throughout Salumbar and its surrounding regions, media reports said.

“Immediate treatment will be provided to any child showing symptoms. Critically ill children are to be referred without delay to district hospitals or medical college facilities,” Rathore said.

Authorities have also initiated preventive measures against possible mosquito-borne diseases, including anti-larval activities, source reduction, and fogging operations in the affected areas.

The Delhi government has announced the expansion of the newborn screening program to improve long-term health outcomes of children.

The move is aimed at achieving near-universal screening at government health facilities and outreach centers, according to an official statement.

From the earlier mandated 1.5 lakh children, the government has expanded the Mission ANMOL (Advanced Newborn Monitoring for Optimal Lifecare) to 2.5 lakh infants to ensure early detection of congenital disorders, PTI news agency quoted the officials as saying.

“The scale-up would enable early identification and management of metabolic, endocrine, functional, and visible congenital conditions, improving long-term health outcomes,” said Health Minister Pankaj Kumar Singh.

Notably, the program will focus on timely intervention and follow-up care for conditions such as

• congenital hypothyroidism,
• congenital heart defects,
• hearing impairment,
• retinopathy of prematurity.

What Is Mission ANMOL

Mission ANMOL was announced by the Delhi government on March 24, 2026, during the Delhi Budget session 2026–27.

Under the ANMOL scheme, 56 types of tests will be conducted using a single drop of blood from newborns, completely free of cost in both public and private hospitals.

Delhi Chief Minister, while presenting the Budget, said the scheme aims to ensure that such tests are not seen as a burden.

"Children are dear to all, they are ‘anmol' (translated as invaluable). To prevent genetic disorders, which are extremely expensive to treat, we are launching this scheme," the Chief Minister said.

Also read: Cancer Is The 10th Leading Cause Of Death In Indian Children: Study

How Will Mission ANMOL Work?

Mission ANMOL will adopt a technology-driven and integrated approach aligned with national guidelines to make comprehensive newborn screening a standard practice across Delhi's public health system.

To support implementation, the government has approved 148 positions under the program, including continuation of 73 existing staff and addition of 60 staff nurses and 15 optometrists, according to officials.

The nurses will assist in sample collection, especially for pre-term and critically ill infants, and help coordinate care and transport, while optometrists will support screening for retinopathy of prematurity, they said.

The initiative will also strengthen coordination among hospitals, laboratories, and program units to ensure all newborns are screened before discharge, with special emphasis on high-delivery-load hospitals and neonatal intensive care units.

Singh said the expanded program reflects the government's commitment to strengthening neonatal healthcare and ensuring that no child is left behind.

Also read: 41 million children aged 5-19 living with high BMI in India: Study

Why Newborn Screening Is Important?

Newborn screening can find the disease before the baby looks sick, and enable early treatment and possible cure for many genetic and metabolic diseases.

Genetic disorders can be life-threatening, impact growth, and even lead to physical and intellectual disabilities. The early screening tests detect hidden conditions early, preventing irreversible brain damage or physical disabilities.

Screening within 24 to 72 hours of birth can provide early access to medical care.

The screening test typically collects a blood sample from the heel of the baby by pricking, and the sample is sent to a laboratory for a biochemical test for screening of inherited conditions.

South Africa's National Department of Health has announced that it has received a first consignment of 37,920 doses of the groundbreaking, six-monthly HIV prevention injection, Lenacapavir.

Lenacapavir is the first twice-yearly injectable pre-exposure prophylaxis (PrEP) product that can help tackle the burden of HIV worldwide.

South Africa has the world's largest HIV-positive population of approximately 8 million people, with over 6 million currently on antiretroviral treatment.

“The department will, in the next few weeks, announce the official launch of this game changer where the phased implementation plan will be outlined,” said department spokesperson Foster Mohale, in a statement.

"Lenacapavir is preventive medicine, not a vaccine, considered one of the most exciting HIV prevention advances in years," Mohale said.

The Department noted that the medicine is expected to be sustain nearly half a million people in South Africa over the next two years, the statement said, adding that is will be officially rolled out in May.

Notably, the initial phase will target high-incidence districts and vulnerable groups.

What Is Lenacapavir?

Lenacapavir is a critical tool for reaching the Global AIDS Strategy goal of ending AIDS as a public health threat by 2030.

Lenacapavir injection as an additional PrEP option offers a highly effective, long-acting alternative to daily oral pills and other shorter-acting options.

With just two doses per year, lenacapavir is a transformative step forward in protecting people at risk of HIV -- particularly those who face challenges with daily adherence, stigma, or access to health care.

Marketed under the brand name Yeztugo, lenacapavir, developed by global pharma major Gilead Sciences, costs $28,218 per person per year.

However, it is being provided to South Africa through a $29-million USD grant from the Global Fund.

The shot was tested in two major studies involving high-risk groups: one with young women and teenage girls in South Africa and Uganda, and another with gay men and gender-diverse individuals in several countries. In both cases, the results were striking.

The women who received the shot had zero new HIV infections, compared to around 2% in those on daily pills. In the second study, the twice-yearly shot proved just as effective for men and gender non-conforming individuals.

“This really has the possibility of ending HIV transmission,” said Greg Millett of amfAR, The Foundation for AIDS Research.

Lenacapavir: How Does It Work?

Yeztugo is administered as two small injections in the abdomen, forming a medication "depot" that slowly releases the drug into the body over six months.

However, people must test negative for HIV before receiving it, as it doesn’t treat existing infections or prevent other sexually transmitted diseases.

Lenacapavir: Why Access Is A Challenge?

Despite its potential, concerns remain over who will actually benefit from lenacapavir.

In the US, only about 400,000 people currently use any form of PrEP — a small fraction of those who could benefit. And structural issues like cuts to public health funding, limited insurance access, and stigma pose significant barriers.

Globally, the challenge is even greater. While Gilead has struck deals with six generic drug makers, including four Indian, to provide low-cost versions of the shot for 120 low-income countries, critics argue that middle-income nations have been left out.

UNAIDS Executive Director Winnie Byanyima noted that at current prices, the shot “will change nothing” for many who need it.