Singer Jesy Nelson recently shared an emotional update regarding the complications she is experiencing in her pregnancy with twin babies. Former Little Mix singer Jesy, who is having twins with partner Zion Foster, announced that she has been diagnosed with pre-twin-to-twin transfusion syndrome (pre-TTTS). The condition, which is present in pregnancies involving twins with a shared placenta, has serious risks involved and needs intense medical supervision. As Nelson embarks on this difficult journey, her story enlightens us about a rare but dangerous condition many expectant parents may not know much about.

Twin-to-twin transfusion syndrome is a rare but dangerous condition that arises in monochorionic twin pregnancies, in which identical twins share a single placenta. The placenta supplies the developing babies with oxygen, nutrients, and blood flow, but in TTTS, there is an imbalance of blood vessels that interconnect the twins, and thus the vital resources are not evenly distributed. One twin, or the donor twin, shares excess blood with the other, referred to as the recipient twin. This leads to one baby becoming malnourished and possibly anemic, and the other in danger of heart problems due to too much blood.

Nelson described her diagnosis in a heartfelt Instagram video, explaining that she is currently in the pre-stage of TTTS and undergoing frequent monitoring. "I am being scanned twice a week, and each time, things have gotten a little worse," she shared, expressing her fears and hopes for the health of her babies.

Potential Risks of TTTS

If left untreated, TTTS can have devastating consequences. Medical research indicates that:

• 90% of the cases of untreated TTTS lead to loss of one or both twins.
• Despite treatment, only a 70% survival rate for both twins is assured.
• Severe forms can result in preterm labor, cardiac failure in the recipient twin, and organ failure in the donor twin.
• Complications in long-term survivors include neurological damage and developmental delay in surviving infants.

TTTS usually advances in stages, beginning with minimal changes in fluid levels and worsening as one twin continues to get an unequal share of blood. In extreme cases, fetal laser surgery, referred to as the Solomon technique, can be employed to divide the blood vessels and balance the twins.

Why Identical Twin Pregnancies Are More Complicated

Identical twins may develop differently, and their own unique form of placental sharing can have a dramatic effect on pregnancy risk. Jesy Nelson's twins are considered monochorionic diamniotic (mono/di), which means they share a placenta but have two amniotic sacs. This is the type of pregnancy in about 70% of identical twin pregnancies and carries an increased risk of complications like TTTS, umbilical cord entanglement, and growth restriction.

Conversely, dichorionic diamniotic (di/di) twins both have a separate placenta and amniotic sac, which greatly diminishes the threat of TTTS. Twin pregnancy type is normally identified by early ultrasound, with physicians being able to track future complications from inception.

Other Twin Pregnancy Health Risks

Twin pregnancies, even without the presence of TTTS, entail a variety of health risks to the mother as well as infants:

1. Premature Birth

Over 60% of twin pregnancies end in premature delivery, with birth usually taking place before 37 weeks. Premature infants can have immature organs and need neonatal intensive care (NICU) assistance to assist with breathing, feeding, and infection fighting.

2. Gestational Hypertension and Preeclampsia

Pregnant women with multiples are at increased risk of having high blood pressure during pregnancy. This, if left untreated, can result in preeclampsia, a serious complication of pregnancy that can result in damage to organs, preterm labor, and in some cases, maternal or fetal death.

3. Anemia

Pregnant women carrying multiples are twice as likely to experience anemia, a condition where the body does not produce enough healthy red blood cells. This can lead to fatigue, dizziness, and complications during delivery.

4. Birth Defects

According to John Hopkins Medicine, multiple birth babies are twice as likely to have congenital abnormalities compared to single births. These can include heart defects, neural tube defects, and gastrointestinal issues.

5. Amniotic Fluid Imbalances

When twins have to share a placenta, they are more likely to have polyhydramnios (excess amniotic fluid) or oligohydramnios (not enough amniotic fluid). Both result in distress to the babies during fetal development and can result in premature labor.

6. Postpartum Hemorrhage

Twins are at increased risk of excessive postpartum hemorrhage because their uterus is larger and there are greater blood supply needs.

Jesy Nelson's openness about her challenging experience is raising awareness for TTTS, a condition that few individuals—let alone expectant mothers and fathers—might be aware of. Through her tearful video, Nelson stressed the significance of knowing about twin pregnancies aside from the thrill of having multiples. "We had no idea that this type of thing occurs when you're having twins. We just desperately want to make people aware of this because there are so many people who aren't aware."

Her case reminds us of the intricacies involved in twin pregnancy and the significance of early identification and medical management. For mothers carrying twins, frequent ultrasounds and vigilance can become a life-and-death issue for early detection and better outcomes of both babies.

Through constant medical attention and care, she and her partner Zion Foster remain positive and get ready for their babies to be born. In other parents whose situations are no different, the story of Nelson highlights awareness, medical progress, and emotional encouragement in handling complicated pregnancies.

The expecting parents of twin siblings are advised to discuss TTTS screening and possible interventions with their physicians to give their babies the best chance.

US President Donald Trump has signed an executive order aimed at changing childhood vaccine recommendations, including moving toward separating the measles, mumps and rubella (MMR) vaccine into individual shots.

The executive order, titled “Delivering Gold Standard Childhood Vaccine Recommendations for Americans,” has sparked debate over how childhood vaccines should be administered and whether combination vaccines should instead be given separately.

Amid criticism of the move, HealthandMe spoke to public health experts to understand whether splitting the MMR vaccine offers any proven health benefit and what it could mean for children and vaccination coverage.

What Does Splitting MMR Mean?

Dr. Sabine Kapasi, Global Health Strategist and a UN Advisor, told HealthandMe that combination vaccines are more than a matter of convenience.

“Combination vaccines are not simply a matter of convenience. They can reduce the number of injections and healthcare visits required, support timely vaccination and help health systems reach children who may otherwise be missed,” she said.

“The more fragmented the pathway becomes, the more important it is to understand its impact on uptake, completion and equity,” Dr. Sabine added.

Dr. Rajeev Jayadevan, former President of IMA Cochin and Convener of the Research Cell, Kerala, also highlighted the practical disadvantage of requiring parents to make additional clinic visits when vaccines that can be administered together are separated.

Is Splitting MMR Healthier?

There is currently no adequate scientific validation for the argument that giving the MMR components separately is inherently healthier, according to Dr. Rajeev.

“The argument that splitting the shots is a healthier option does not have adequate scientific validation, because the body’s immune system routinely encounters numerous antigens simultaneously and effectively in everyday life,” he told HealthandMe.

Dr. Sabine emphasized that any change to childhood immunization policy should be based on evidence rather than simply altering an established schedule.

“Any change to childhood immunization policy should therefore be grounded in transparent evidence, rigorous safety and effectiveness assessment, and real-world data on vaccination coverage and completion,” she added.

Could More Vaccine Visits Increase Hesitancy?

Separating combination vaccines could make vaccination more cumbersome for families by requiring additional visits.

Dr. Sabine said vaccination programs operate within different health systems, meaning even small changes in scheduling can have implications for access, logistics, costs and continuity of care.

“The priority should remain consistent: designing immunization systems that are evidence-led, accessible and resilient enough to protect children across populations—not simply changing the schedule for the sake of changing it,” she said.

In a post on X US Senator Bill Cassidy, a physician, also criticized the executive order and warned that breaking up combination vaccines could mean children need more shots to receive the same protection.

“It will increase hesitancy and make children less safe,” he said, urging parents to discuss vaccination decisions with their child’s pediatrician.

Former White House COVID-19 Response Coordinator Dr. Ashish Jha said European countries do not routinely split the MMR vaccine into three separate shots. “No European country splits the MMR vaccine as 3 separate shots,” he said in a post on X.

He added that Russia and Tajikistan were historical partial exceptions but have since moved to full MMR vaccination.

Are There Any Potential Advantages?

Dr. Rajeev said one potential advantage of the new approach is the separation of vaccines into essential and optional categories.

He said this could give parents greater clarity about which vaccines are considered the highest priority and potentially help address some forms of vaccine hesitancy. The expert also pointed to US policy around childhood COVID-19 and influenza vaccines, saying that making these vaccines a shared decision between doctors and parents could be viewed as a progressive step.

Dry or burning eyes are often brushed aside as side effect of ageing. But new research suggests that for postmenopausal women, the problem may be more than just eye irritation.

A recent study in Post Reproductive Health found that postmenopausal women had more severe signs of dry eye disease (DED) than both younger women and men in the same age range.

Researchers say the condition is caused largely by tear-film instability and dysfunction of the meibomian glands, the tiny glands in the eyelids that produce the oily layer of tears.

The study included 319 participants: 102 postmenopausal women, 105 age-matched men and 112 younger healthy women.

Researchers assessed symptoms, tear production, tear-film stability, damage to the eye surface and meibomian gland function.

Postmenopausal women had the highest rate of severe dry eye, affecting 24.5%, compared with 16.2% of age-matched men and 18.8% of younger women.

They also had higher scores for dry-eye symptoms, more straining of the of the ocular-surface, shorter tear-break-up time and greater meibomian gland dysfunction. 20.6% of postmenopausal women reported burning.

Effect Of Menopause On Eye Health

Also read: Experimental Menopause Drug Shows Promise Mid-Stage Trial, Reduces Hot Flashes By 83%

The connection between eyes and menopause lies in the significant hormonal changes women face as they enter menopause.

The ocular surface, lacrimal glands and meibomian glands are affected by sex hormones, including oestrogen and androgens. When hormone levels change during and after menopause, these tissues may also function differently.

One of the important consequences of menopausal hormonal shifts is the disruption of the tear film. The tear film is like a thin protective coating over the eye. It contains an oily outer layer that slows evaporation. The meibomian glands produce this oil.

When these glands do not work properly, tears can evaporate too quickly. Doctors call this condition evaporative dry eye.

Dry Eye Does Not Mean The Eyes Have Stopped Producing Tears

Also read: Post-Menopausal Women Face A Higher Risk Of Fatty Liver Disease: How Falling Oestrogen Levels Impact Liver Health

Dry eye does not necessarily mean the eyes have stopped producing tears. In many postmenopausal women, the tears may not remain stable on the eye for a long time.

As the oily layer becomes impaired, tears evaporate faster. This can increase tear concentration, trigger inflammation and damage the ocular surface, creating a cycle of dryness and irritation.

Hormonal changes during menopause may contribute to this process, although researchers are still working to understand exactly how individual hormones influence dry eye.

A 2026 review also highlights increasing evidence that hormonal changes may interact with immune and inflammatory pathways on the ocular surface, rather than simply reducing tear production.

What Symptoms Should Postmenopausal Women Watch For?

Persistent burning, itching, grittiness, redness, light sensitivity, watery eyes or fluctuating vision can all occur with dry eye disease.

The latest study also found that clinical signs of disease were more severe in postmenopausal women even though symptom scores did not always differ significantly from other groups. This finding makes eye examinations particularly important during and after menopause.

The researchers concluded that recognising these differences could improve diagnosis and help doctors better understand the hormonal contribution to dry eye disease.

About one in 20 adults in the US hospitalized with firearm injuries develop bacterial infections, according to a study.

The findings, published in JAMA Network Open as a research letter, showed that most infections occur during the initial hospitalization rather than after patients return home.

While firearm injuries are a major public health concern in the US, very little research has examined infectious complications that can occur after treatment.

"Firearm injury is a recognized risk for bacterial infection, but no large studies have described how often such infections occur and which patients are most at risk," said Jonathan D. Baghdadi, associate professor of epidemiology and public health at the University of Maryland School of Medicine (UMSOM).

Most Infections Emerged Early

To better understand the risks after gunshot injuries, researchers analyzed data from 24,024 adults hospitalized with firearm injuries at 323 hospitals across the country between January 2019 and May 2021.

The study found that 1,236 patients—about 5%—developed a bacterial infection. Most cases occurred during the initial hospitalization, with only 1.3% occurring during the 90-day follow-up period.

Researchers also found that patients who underwent surgeries involving the head, neck, spine, liver or lower abdomen faced the highest risk of developing bacterial infections.

Who Faced the Greatest Risk?

The risk was more common among patients undergoing head, neck, spine or lower-abdominal surgery were especially vulnerable to bacterial infections.

The team found that most commonly identified pathogens patients were Escherichia coli, Staphylococcus aureus and enterococci. These pathogens are known to acquire dangerous resistance, creating major challenges in hospitals and communities worldwide

Antibiotic exposure among patients who did not develop infections was generally low, which researchers said reflects current recommendations to limit preventive antibiotic use when there is no bacterial infection.

Bacterial infection was not independently linked to a higher risk of death among patients who survived at least one night in the hospital.

Study Limitations

The authors noted that the research relied on administrative hospital data and that complete follow-up information may not have been available for every patient.

Nonetheless, the large national dataset provided an opportunity to evaluate infection risk across a broad and diverse patient population.

"Recovery from firearm injuries can be complicated. Although our study focused on mortality, infections can impact recovery in multiple ways, contributing to long-term pain and disability," Baghdadi said.

"By identifying the patients most likely to develop these complications, we hope this work contributes to more informed clinical decision-making and ultimately better outcomes for patients."

Baghdadi hopes that by developing a definition to identify patients with bacterial infection after firearm injury using observational and administrative datasets, and demonstrating how to apply it, other researchers will use the approach to conduct studies targeting more specific clinical questions.