Pope Francis (Credit: X)
Pope Francis injured his right arm after suffering a fall earlier this week. According to the Vatican, while the 88-year-old pontiff did not break his arm, a sling was put on as a precaution. This incident comes just weeks after another fall on December 7, where he hit his chin on a nightstand, resulting in another, visible bruise. The pope's health has been a topic of ongoing speculation due to his age and medical history, which includes long bouts of bronchitis and mobility challenges. Often seen using a wheelchair or a cane, Francis also uses a walker within the Vatican's Santa Marta hotel, where he resides. Notably, his frailty has brought renewed attention to the risks of falls among elderly individuals and the steps one must follow to mitigate such falls.
A study published in Frontiers in Aging Neurosciences people get older, the bone density in the lower back and thigh bone decreases significantly. This raises the risk of osteoporosis (OP). Therefore it becomes pivotal to pay early attention to nutrition, exercise ability, vitamin D levels, and uric acid levels in older individuals to prevent Ostreopsis and mitigate fall risks. The risk of falls and bone injuries among elderly individuals underscores the importance of preventive measures for maintaining bone health and minimizing fall risks.
Elderly, particularly menopausal women, require a daily calcium intake of 1,200 mg, divided into two or more doses. This can be achieved through dietary sources such as dairy and non-dairy products or through supplements like calcium carbonate and calcium citrate. However, total daily calcium intake should not exceed 2,500 mg to avoid potential health risks.
Vitamin D is essential for calcium absorption and bone mineralization. While sunlight exposure helps synthesize vitamin D, older individuals often require supplements due to reduced skin synthesis and the limited availability of foods. Fortified milk and supplements containing 200–600 IU of vitamin D daily are recommended, with higher doses required for those with deficiencies. Severe cases may necessitate high-dose treatments, such as 50,000 IU weekly for up to three months, along with regular monitoring of calcium and vitamin D levels.
Regular exercise is vital for preserving bone mass and reducing fall risk. Weight-bearing activities, strength training, and balance exercises like brisk walking or skipping can enhance bone density and improve coordination. Experts recommend at least 30 minutes of moderate physical activity most days of the week, supplemented by strength training twice weekly. For individuals unable to engage in standard exercise routines, alternatives like vibrating platforms may help maintain bone health.
Falls remain a leading cause of fractures among individuals over 60. Addressing contributing factors such as balance issues, vision problems, and environmental hazards can significantly reduce risks. Preventive measures include regular vision checks, minimizing medications causing dizziness, improving home safety (e.g., installing railings and removing loose rugs), and wearing rubber-soled footwear. Hip protectors may also help mitigate the impact of falls.
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Pancreatic cancer is one of the most difficult cancers to detect in its early stages. By the time it is diagnosed, the disease may have already spread, limiting treatment options and lowering survival.
Now, a novel blood test called Panxeon, developed by researchers at City of Hope, could offer a way to detect pancreatic cancer earlier.
Panxeon is an investigational liquid biopsy designed to detect pancreatic cancer, including stage 1 and 2 disease, using a blood sample.
The test also showed potential for identifying high-grade dysplasia, a precancerous condition sometimes considered “stage 0” pancreatic cancer.
In a study of nearly 1,800 patients across the US, Europe and Asia, published in Nature Medicine, the blood test correctly identified stage 1 and 2 pancreatic cancer in 87% of cases. Its false-positive rate was 3% among people in low-risk groups and 16% among those in high-risk groups.
Panxeon also detected high-grade dysplasia more than 64% of the time. This could help doctors identify which pancreatic cysts may require closer monitoring or further intervention before invasive cancer develops.
Pancreatic cancer has one of the lowest survival rates among cancers. Only 14% of patients survive five years after diagnosis, according to the US National Cancer Institute.
Panxeon assesses three biological signals associated with pancreatic cancer: circulating microRNAs, exosomal microRNAs and a protein called CA19-9.
The test then uses artificial intelligence to combine these measurements into a single score estimating a person's risk of pancreatic cancer.
“Pancreatic cancer remains so deadly largely because we find it after the window for cure has begun to close,” said senior author Ajay Goel, chair of the Department of Molecular Diagnostics and Experimental Therapeutics at City of Hope.
“For patients, these findings represent progress toward finding pancreatic cancer before symptoms appear and while more treatment options remain available,” he added.
According to the researchers, Panxeon is the first investigational test to combine these three biomarkers into a single blood test.
However, Panxeon is not intended to replace imaging or other diagnostic tests. Instead, it could potentially help identify people at higher risk who need further evaluation, said Goel.
Read More: Former US Senator Ben Sasse Opens Up About Battle With Terminal Stage 4 Pancreatic Cancer
Early detection of pancreatic cancer has been a longstanding research challenge, with previous blood-based tests failing to provide sufficient accuracy.
The researchers said Panxeon's approach differs by combining multiple biomarkers and evaluating the test in people with risk factors such as inherited or familial risk, pancreatic cysts and chronic pancreatitis, rather than relying only on healthy controls.
“Most biomarkers tell you one part of the story. Combining multiple biological signals gives us a clearer picture of what may be happening in the pancreas,” Goel said.
People who may potentially benefit from such testing include those with an inherited risk or family history of pancreatic cancer, pancreatic cysts or chronic pancreatitis.
These groups are often monitored using imaging and other tests. A reliable blood test could eventually help identify who needs further evaluation.
“A stage shift is not just a statistic,” Goel said. “The earlier we find pancreatic cancer, the greater the chance that meaningful intervention is still possible.”
READ: Daraxonrasib: US FDA Approves Once-Daily Pill for Metastatic Pancreatic Cancer
Pancreatic cancer can begin with few or nonspecific symptoms, making early diagnosis difficult. Symptoms may become more apparent as the disease progresses.
Symptoms that should not be ignored include:
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Newly released national sexual health data shows that Australia is seeing an alarming rise in STIs like syphilis and gonorrhoea. The data from Kirby Institute at UNSW Sydney shows that diagnoses have increased by more than 50% over the past decade.
In 2025, Australia recorded 5,986 syphilis diagnoses and 42,393 gonorrhoea diagnoses, with rates of both infections shooting up by more than 50% since 2016.
Apart from the sharp rise in cases, one pattern that has drawn attention is the difference in the number of infections between men and women. Syphilis diagnoses among women increased 167% over the past decade, compared with a 39% increase among men.
Health experts say the rise is especially alarming as syphilis, when left untreated, can cause miscarriage, stillbirth, congenital syphilis and infant death.
Also read: Ferritin Face: Can Pale Skin Signal Iron Deficiency?
Syphilis is caused by the bacterium Treponema pallidum and the infection unravels in stages. The first stage causes a painless sore, called a chancre, typically at the site where the bacteria entered the body. The sore can occur around the genitals, anus, rectum, lips or mouth and may disappear on its own within weeks.
The disappearance of that sore could be misleading because when it heals, it does not mean that the infection has not necessarily gone away.
Without treatment, syphilis can progress to a second stage, which comes with a rash, swollen lymph nodes, fever, fatigue, and other symptoms. These symptoms can also eventually disappear.
If left untreated, the infection can then enter its latent stage, when a person has no visible signs or symptoms. This is what makes syphilis particularly difficult to detect.
During latent syphilis stage, the bacteria remain in the body even though the person may feel completely well. According to the US Centers for Disease Control and Prevention, untreated syphilis can remain in the body for years.
The latest Australian data show men accounted for 78% of syphilis diagnoses in 2025, but the much faster increase among women is raising particular concern because an infected pregnant woman can pass the bacteria to her unborn baby.
Dr Skye McGregor, an epidemiologist at the Kirby Institute said, “It’s really concerning because the rise among women has contributed to syphilis in pregnancy, which can cause miscarriage, stillbirth, congenital syphilis and infant deaths,” McGregor said. “These are really substantial impacts on infants, but also the community as a whole. Across that same 10-year reporting period, there were 113 congenital syphilis cases and, tragically, 40 of those infants died.”
Australia recorded 14 cases of congenital syphilis in 2025. Over the past decade, there have been 113 reported congenital syphilis cases, with 40 resulting in infant deaths.
The infection is preventable from reaching the baby when it is identified and treated during pregnancy. To curb the same, Australia has recently updated national guidelines to recommend at least three syphilis tests during pregnancy, reflecting concern about rising infections.
Not everyone with untreated syphilis develops latent-stage disease. But in some people, the infection can eventually damage multiple organs.
Tertiary syphilis can affect the heart and blood vessels, brain and nervous system, and several other organs. It can emerge 10 to 30 years after the original infection and can cause severe disability or death.
Syphilis can also affect the nervous system, eyes or ears at different stages of infection. Neurosyphilis can cause headaches, weakness, problems with movement, confusion or cognitive changes.
Ocular syphilis can cause vision problems and potentially permanent vision loss, while otosyphilis can cause hearing loss, tinnitus or dizziness.
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India’s Ministry of Health and Family Welfare has issued an advisory stating that stem cell therapy should be used as standard care only for diseases or indications approved by the Ministry.
The advisory reiterates the existing regulatory framework governing stem cell research and therapy.
The advisory directs that stem cell therapy for Autism Spectrum Disorder (ASD) be restricted to approved clinical trials.
This aligns with the National Guidelines for Stem Cell Research, 2017, issued by the Indian Council of Medical Research (ICMR) and the Department of Biotechnology (DBT), along with other applicable government instructions.
The advisory also says unproven stem cell interventions, including those for ASD, should not be offered as “routine, standard or commercial clinical services.”
“All States and Union Territories must adopt the Clinical Establishments (Registration and Regulation) Act, 2010, regarding regulation of stem cell therapy,” the Ministry said.
The directions apply to government and private clinical establishments involved in stem cell research, treatment, promotion or administration.
The Supreme Court had earlier ruled against the use of stem cell therapy for autism outside approved clinical trials. The National Medical Commission (NMC) has also warned doctors and hospitals against offering it as routine treatment for ASD.
Also read: Autism Care Begins Early: Why the First 1,000 Days Matter Most, Says AIIMS Expert
The Ministry has asked States and Union Territories to ensure that hospitals, clinics and other establishments involved in stem cell research or treatment comply with the regulatory framework.
The Supreme Court, in its January 30, 2026 judgment, said violations can lead to professional misconduct proceedings, as well as action under the Clinical Establishments Act, including cancellation of registration and penalties.
In its September 5, 2026 advisory, the National Medical Commission (NMC) said stem cell therapy can be offered as standard clinical care only for approved indications.
Unauthorized administration, prescription, promotion or advertising of stem cell therapy beyond approved indications may amount to professional misconduct, it said.
State Medical Councils have been asked to examine alleged violations and take disciplinary action where professional misconduct by a registered medical practitioner is established after due process.
Earlier this year, ICMR Director-General Dr Rajiv Bahl told the NMC that stem cell treatment could be used in regular medical practice only for 32 government-approved diseases.
These include:
The ICMR DG asked doctors not to offer stem cell therapy for diseases outside the approved list. Current international guidelines also do not recommend stem cell therapy as a treatment for ASD.
In January, a Supreme Court bench comprising Justice JB Pardiwala and Justice R Mahadevan said stem cell therapy lacks “scientific support” and has not been recognized as a sound medical practice backed by empirical evidence.
The Bench ruled that “every use of stem cells in patients outside an approved clinical trial is unethical and shall be considered as malpractice.”
The Court said stem cell therapy can still be studied through monitored clinical research trials, and patients can participate in approved and regulated trials.
Stem cell therapy, also called regenerative medicine, uses stem cells to repair or replace damaged tissues.
While stem cell therapy is used for certain blood cancers and blood disorders, there is no established scientific evidence supporting its use as a treatment for autism.
Stem cell therapy remains vastly unregulated in India, and some private labs have been making money by promising treatment for autism, according to experts.
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