Pope Francis (Credit: X)
Pope Francis injured his right arm after suffering a fall earlier this week. According to the Vatican, while the 88-year-old pontiff did not break his arm, a sling was put on as a precaution. This incident comes just weeks after another fall on December 7, where he hit his chin on a nightstand, resulting in another, visible bruise. The pope's health has been a topic of ongoing speculation due to his age and medical history, which includes long bouts of bronchitis and mobility challenges. Often seen using a wheelchair or a cane, Francis also uses a walker within the Vatican's Santa Marta hotel, where he resides. Notably, his frailty has brought renewed attention to the risks of falls among elderly individuals and the steps one must follow to mitigate such falls.
A study published in Frontiers in Aging Neurosciences people get older, the bone density in the lower back and thigh bone decreases significantly. This raises the risk of osteoporosis (OP). Therefore it becomes pivotal to pay early attention to nutrition, exercise ability, vitamin D levels, and uric acid levels in older individuals to prevent Ostreopsis and mitigate fall risks. The risk of falls and bone injuries among elderly individuals underscores the importance of preventive measures for maintaining bone health and minimizing fall risks.
Elderly, particularly menopausal women, require a daily calcium intake of 1,200 mg, divided into two or more doses. This can be achieved through dietary sources such as dairy and non-dairy products or through supplements like calcium carbonate and calcium citrate. However, total daily calcium intake should not exceed 2,500 mg to avoid potential health risks.
Vitamin D is essential for calcium absorption and bone mineralization. While sunlight exposure helps synthesize vitamin D, older individuals often require supplements due to reduced skin synthesis and the limited availability of foods. Fortified milk and supplements containing 200–600 IU of vitamin D daily are recommended, with higher doses required for those with deficiencies. Severe cases may necessitate high-dose treatments, such as 50,000 IU weekly for up to three months, along with regular monitoring of calcium and vitamin D levels.
Regular exercise is vital for preserving bone mass and reducing fall risk. Weight-bearing activities, strength training, and balance exercises like brisk walking or skipping can enhance bone density and improve coordination. Experts recommend at least 30 minutes of moderate physical activity most days of the week, supplemented by strength training twice weekly. For individuals unable to engage in standard exercise routines, alternatives like vibrating platforms may help maintain bone health.
Falls remain a leading cause of fractures among individuals over 60. Addressing contributing factors such as balance issues, vision problems, and environmental hazards can significantly reduce risks. Preventive measures include regular vision checks, minimizing medications causing dizziness, improving home safety (e.g., installing railings and removing loose rugs), and wearing rubber-soled footwear. Hip protectors may also help mitigate the impact of falls.
Credit: University of Vermont
Scientists have identified a rare contagious skin cancer in brown bullhead catfish living in lakes across the US and Canada's Quebec, marking only the fourth known case of a naturally transmissible cancer in the animal kingdom.
A team led by the University of Vermont found that mysterious black skin lesions affecting brown bullhead catfish in Lake Memphremagog and other lakes in New England and Quebec were caused by a transmissible melanoma—the first such cancer ever identified in a freshwater fish species.
The findings, published in the journal Nature, add freshwater fish to a short list of species known to develop cancers that spread through the transfer of living cancer cells. Previously, transmissible cancers had been identified only in Tasmanian devils (facial tumor disease), dogs (canine transmissible venereal tumor), and shellfish, including clams, mussels, and other bivalve mollusks (leukemia-like transmissible cancers).
“The cancer cells behave more like parasites than conventional tumors, moving from fish to fish,” said the researchers led by the University of Vermont.
"The discovery sheds light on how cancer can spread in the wild and raises important questions about where this cancer originated, how it will affect fish health and populations—and how cancer works in all animals including humans," they added.
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Since 2012, anglers and biologists have reported increasing numbers of brown bullhead catfish with raised black skin patches in Lake Memphremagog, which straddles Vermont and Quebec. By 2014, nearly one in three fish examined had developed the dark lesions.
Initially, researchers believed the disease might be caused by a virus. They later suspected pollution or another environmental pathogen. However, further investigation revealed that the lesions were actually melanoma.
“This was surprising, and we wanted to know how a bottom-dwelling fish was getting a cancer we associate with exposure to too much sunlight,” said Julie Dragon, a scientist at the University of Vermont.
Using whole-genome sequencing, the team identified hundreds of thousands of shared genetic variants among tumor samples that were absent from the host fish, confirming that the cancer spreads between animals through living cancer cells.
Researchers are now trying to determine exactly how the cancer moves from one fish to another. They believe that the tumors appear only "in larger fish that are of spawning age".
Mark Henderson, a fish biologist and study co-leader in UVM’s Rubenstein School of Environment and Natural Resources said that it “maybe some part of spawning behavior leads to the spreading of the cancer between animals."
During spawning, brown bullhead gather closely in shallow water, allowing physical contact that could transfer tumor cells. Because the fish lack scales and spend much of their time on lake bottoms, scientists also believe sediments could harbor free-floating cancer cells.
The study also suggests that naturally occurring arsenic or hormonal changes may weaken the fish's immune system, making them more susceptible to infection.
Despite the unusual discovery, researchers stress that there is no known risk to humans.
Lake Memphremagog supplies drinking water to more than 175,000 people, but scientists say the cancer cells cannot infect or survive in another species. They also state that the fish are safe to handle for research and monitoring.
Fish remains a highly nutritious food, rich in high-quality protein, vitamin D, and omega-3 fatty acids that support heart and brain health.
Quebec's Ministry of the Environment recommends not eating fish with tumors, even though there is no evidence that doing so poses a risk to human health.
The findings raise broader questions about how pollution, habitat stress, and climate change may influence the evolution and spread of diseases in wildlife.
Credit: AI
With long COVID continuing to affect millions, a recent study has emerged, suggesting that women are more likely to bear its neurological burden than men.
According to a new study from Northwestern Medicine, female patients reported more severe neurological symptoms, poorer cognitive function, and a greater decline in quality of life.
Published in the Annals of Clinical and Translational Neurology, the study analyzed 2,329 adults evaluated at Northwestern Medicine's Neuro COVID-19 Clinic between May 2020 and August 2025. Researchers compared neurological symptoms in patients, examining differences between men and women.
Researchers found that women, on average, reported significantly more neurological symptoms about 16 months after their COVID-19 illness than men. Among the most commonly reported symptoms were:
Women also scored worse on measures of cognitive performance and reported a greater impact on their overall quality of life.
Lead author Dr. Igor Koralnik, chief of Neuroinfectious Diseases and Global Neurology at Northwestern Medicine, said, "While previous studies showed that women are more likely to develop long COVID, this is the first study demonstrating that women also experience more severe neurological symptoms, worse cognitive function and greater reductions in quality of life than men."
First author Dr. Aurore Gorenshtein added, "Recognizing these sex-specific differences is important because it may help clinicians provide more personalized care and improve treatment strategies for people living with neurological long COVID."
Even though the study did not narrow down the exact causes behind these differences, researchers believe that several biological and immune-related factors could contribute. Here are some possible explanations:
The new research aligns with earlier findings from the U.S. National Institutes of Health's RECOVER Initiative, which showed that females are generally more likely than males to develop long COVID. That analysis also suggested the risk is highest among women aged 40 to 54 years, particularly before menopause.
A study recently found out that long COVID may directly injure the brain's dopamine system, offering an explanation for symptoms like fatigue, brain fog, poor memory, slowed movement, and lack of motivation that persist long after the initial infection. The latest findings shed more light on deeper effects of long COVID on brain health.
Long COVID remains a major public health challenge, with neurological symptoms among the most persistent and disabling. Brain fog, memory problems, chronic fatigue, headaches and dizziness can significantly affect employment, education and daily life.
The latest findings suggest that healthcare providers may need to consider sex-specific approaches when evaluating and managing patients with neurological long COVID, ensuring women receive earlier recognition, cognitive assessments and personalised rehabilitation.
Credit: iStock/Canva
Montelukast, a widely prescribed medication for asthma and allergies, may cause significant psychiatric side effects that remain underdiagnosed and underreported, according to researchers.
The researchers, from the University of California, Davis in the US, and Curtin University in Australia, said many psychiatrists are still unaware of the US Food and Drug Administration's (FDA) black-box warning on the drug's mental health risks.
In 2020, the FDA had required a black-box warning for montelukast, citing the risk of serious behavior and mood-related changes, including suicidal thoughts or actions.
Writing in Psychiatry Online, the researchers said that estimates of montelukast-related neuropsychiatric events range from 5.9% to 62%.
Reported psychiatric side effects include:
Symptoms may appear soon after starting the medication, after prolonged use, or even following its withdrawal.
The researchers noted that children appear to be disproportionately affected, partly because montelukast is available as a chewable tablet that is easier for young children to take than inhaled medications.
Citing a 2016 study, they wrote that completed suicides were reported more frequently among children than among adolescents or the overall population.
Behavioral changes in children may also be mistaken for normal developmental phases, delaying recognition of a possible drug-related cause.
The researchers also highlighted testimony presented at a 2022 US National Center for Toxicological Research (NCTR) meeting, where a parent described severe behavioral changes in her three-year-old son after taking montelukast.
Many parents at the meeting said they only discovered the possible link between the medication and psychiatric symptoms by chance, despite consulting multiple healthcare providers.
Researchers said patients and clinicians frequently fail to connect psychiatric symptoms with montelukast because there is no obvious reason to suspect the medication.
They also argued that inadequate communication from drug manufacturers and health regulators has contributed to low awareness, despite safety warnings issued in several countries.
They cautioned that abruptly stopping montelukast may also worsen psychiatric symptoms, making clinical evaluation essential.
The researchers recommend that psychiatrists consider montelukast as a possible cause when psychiatric symptoms develop after the medication is started.
If a link is suspected, psychiatrists should coordinate with the patient's primary care physician to discuss alternative treatments for asthma or allergies and monitor whether psychiatric symptoms improve.
They also advise clinicians to:
The FDA states that montelukast prescribing information already includes warnings about mental health side effects, including suicidal thoughts or actions. However, it notes that many healthcare professionals and patients remain unaware of these risks.
The agency advises that:
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