Daytime Sleepiness (Credit: Canva)
Experiencing daytime sleepiness is something that is usually perceived as a minor inconvenience, but for older adults, it could be an early warning sign of Dementia. This neurodegenerative disease leads to the progressive decline of brain cells. This eventually
affects memory, cognition, and personality, making everyday tasks more difficult. As one of the fastest-growing neurological disorders across the world, dementia poses a significant health threat to ageing populations.
For this study, researchers followed 445 older adults (average age 76) over three years, aiming to determine whether poor sleep could increase the risk of mild cognitive impairment (MCI), which often leads to dementia. At the start, none of the participants had MCI, but by the end of the study, 36 individuals had developed the condition.
The researchers discovered that participants with poor sleep were more likely to develop MCI compared to those who slept well. However, when depression symptoms were taken into account, the link between poor sleep and MCI became less pronounced, suggesting that while sleep issues are a concern, mental health also plays a key role in dementia risk.
To assess sleep quality, the Pittsburgh Sleep Quality Index (PSQI) was used, evaluating factors such as sleep duration, disturbances, and daytime alertness. Among these, "daytime dysfunction"—defined as excessive sleepiness and low energy during the day—was most strongly associated with an increased risk of MCI. Those experiencing daytime dysfunction were more than three times as likely to develop MCI as those who didn’t report such symptoms.
There are many types of dementia:
Dementia is not a specific disease. According to the Centers for Disease Control and Prevention (CDC), it is an overall term that describes a decline in mental ability that interferes with daily life. People with dementia often have symptoms like trouble remembering, thinking, or making everyday decisions. These symptoms tend to get worse over time.
Alzheimer’s disease is the most common type of dementia, and it mostly affects the elderly. Each form of dementia has a different cause. Though dementia mostly affects older adults, it is not a part of normal ageing. An estimated 6.7 million older adults have Alzheimer's disease in the United States. That number is expected to double by 2060, as per data from the CDC.
In 2022, 3.8% of men and 4.2% women in US were diagnosed with dementia. The percentage of people increase with age from 1.7% for those aged 65-74 to 13.1% for those aged 85 and older. Alzheimer's accounts for 60 to 80% of all dementia cases and it is most prevalent in California, Florida, and Texas, as these states have the highest number of people.
Credit: US FDA
The US Food and Drug Administration (FDA) has announced a recall of mangoes sold at Walmart in at least four states because they may be contaminated with Salmonella.
New York-based Panorama Produce "is recalling 302 boxes of size 9 mangoes because they may be contaminated with Salmonella", according to the recall notice.
The mangoes were sold at select Walmart stores in four states:
Also read: US FDA Recalls Injectables Over Fiberglass, Steel Particles: See Affected Drugs
The company said that the recalled mangoes are packaged in a Martina-branded case.
Individual mangoes can be identified by a light blue sticker bearing the labels Agrofepac, Produce of Mexico, PLU number 4584 and UPC 07503061948050.
The recall was initiated after FDA sampling found Salmonella in mangoes grown on the same farm, although those sampled mangoes were not distributed into US commerce.
The recalled mangoes and the sampled mangoes share the same source. Therefore, Panorama Produce initiated the recall. The company, however, stated that no illnesses have been reported to date in connection with the recalled product.
Read More: From Dog Food To Fruit Bars: Over 10 Products Recalled In US Over Contamination
The company advised consumers to use the product identifiers above to determine whether their mangoes are included in the recall.
Consumers who have the recalled mangoes should dispose of them or return them to the place of purchase. Anyone who believes they may have become ill should contact a healthcare provider.
Food safety has become a serious concern in the US in recent months, with a large number of products recalled over contamination, bacterial infections and other health risks.
The recalls involve food products ranging from rice and donuts to eggs and fruit bars, among a host of other products.
Experts blamed federal funding cuts under the Trump administration, which reduced budgets for food inspections by federal agencies and grants to state and local health departments that conduct traceback investigations to determine where outbreaks originate.
Salmonella is a bacterial infection that commonly causes diarrhea and gastrointestinal illness. Food contaminated with Salmonella bacteria does not usually look, smell or taste spoiled.
Common Symptoms
Anyone can become sick with a Salmonella infection. Most people recover without medical treatment. However, children, older adults and people with weakened immune systems may develop serious illness requiring medical care.
The bacteria can spread by eating contaminated food, through contact with contaminated environments or from person to person.
Health officials have advised consumers to follow recall instructions and avoid eating affected products.
Credit: AI
Type 2 diabetes may be the same disorder, but it may look quite different in men and women. A new study based on 28,720 people newly diagnosed with type 2 diabetes has found distinct patterns in the complications that come after diagnosis.
Men were more likely to follow a trajectory involving cardiovascular disease or end-stage kidney disease, while women were more likely to develop mental health conditions like anxiety, depression or somatoform disorders.
The study, published in PLOS Medicine, followed patients diagnosed between 2010 and 2020 using linked UK healthcare records.
Participants were followed for a median of 6.8 years, allowing researchers to examine not just which complications occurred, but also the order in which they developed.
Among men, 8.4% followed a trajectory involving cardiovascular disease or end-stage renal disease, compared with 5.3% of women. Men also tended to develop these complications earlier than women.
Hypertension, however, remained the most common complication across both sexes, affecting 21.1% of men and 20.2% of women.
The finding matters because type 2 diabetes can damage blood vessels over time, increasing the risk of cardiovascular disease and kidney problems. But the study suggests that the sequence and timing of these complications may not be identical in men and women.
Also read: US FDA Approves Eli Lilly’s Mounjaro To Reduce Cardiovascular Risk In Diabetics
8.1% of women developed a mental health condition compared with 5.3% of men. These included anxiety, depression and somatoform disorders.
Prof Ravinder Goswami, senior endocrinologist at AIIMS, told the Times of India that diabetes can affect men and women differently. He noted that men may develop diabetes at a younger age, while women with diabetes can lose the natural cardiovascular protection generally associated with the premenopausal period.
Also read: Lowering Cholesterol May Protect Your Brain As Study Links Statins To 15% Lower Dementia Risk
Sex hormones, body-fat distribution, age at diabetes diagnosis, cardiovascular risk factors and differences in seeking healthcare can all influence how complications related to type 2 diabetes emerge.
The study found that women had higher average healthcare utilisation. On the other hand, lower healthcare engagement among some men could represent a missed opportunity to detect complications earlier.
The researchers also found that people who developed a mental health condition after their diabetes diagnosis had a shorter survival trajectory. Among people following the same disease pathway, men died on average nine years younger than women.
That does not mean depression or anxiety automatically shortens a person's life by nine years. Rather, the finding highlights how the combination of diabetes and subsequent health problems can identify a particularly vulnerable group.
The researchers say their study supports sex-specific complications of diabetes and earlier intervention, rather than completely separate treatments.
For men, that could mean paying particular attention to cardiovascular and kidney health. For women, routine attention to mental health alongside physical complications is especially important.
The study is observational, so it cannot prove that being male or female directly causes a particular diabetes complication.
Credit: AI
A visit to a petting zoo usually means excited children playing around with a few goats. But in North Carolina, an ordinary animal encounter has triggered a public health warning after four baby goats linked to a mobile petting zoo tested positive for rabies.
The goats belonged to Farm Adventures, a mobile petting zoo based in Harmony, North Carolina. Three goats tested positive for rabies at the North Carolina State Laboratory of Public Health on August 28, while a fourth was not tested but was presumed infected. All the four animals were euthanised.
Health officials are now urging anyone who touched or held the baby goats between July 28 and August 27 to contact their local health department and find out whether preventive treatment is needed. The animals had appeared at events across several North Carolina counties during that period.
According to the North Carolina Department of Health and Human Services (NCDHHS), the goats were most likely exposed when a skunk entered their pen in late July.
The petting zoo said the goats were too young to receive rabies vaccinations at the time and staff did not know they had been bitten. The animals also showed no obvious signs of rabies, making the infection difficult to spot before testing.
That brings us to one of the most unsettling features of rabies. An infected animal does not necessarily look obviously sick at the time a person encounters it.
NCDHHS said the goats “may have been in direct contact with people at events while infectious” and is working with local health departments and event organisers to identify people who could have been exposed.
Also read: Bird Flu In US: Are Cats Spreading A Deadly Disease?
Rabies is caused by a virus that attacks the central nervous system. The most common route is an infected animal's bite, because the virus is present in saliva. Scratches contaminated with saliva can also pose a risk. Simply being near an infected animal does not mean you are exposed to rabies.
Once the virus enters the body, it can travel through peripheral nerves towards the brain and spinal cord. This helps explain why there can be a considerable gap between exposure and symptoms. It can last weeks to months, depending partly on where the exposure occurred and how far the virus has to travel to reach the brain.
Also read: Is There A Difference Between Zoonotic, Non-Zoonotic And Reverse Zoonotic Diseases
This is where rabies becomes particularly dangerous. In the early stage, symptoms can resemble many ordinary illnesses, including fever, weakness and headache. There may also be pain, tingling or itching around the site of the bite.
But once the virus reaches the brain, the disease can progress to encephalitis, causing confusion, agitation, hallucinations, difficulty swallowing, excessive salivation, seizures and paralysis.
The CDC states that once clinical signs of rabies appear, the disease is nearly always fatal. There. By the time neurological symptoms appear, the virus has already established itself in the nervous system, where eliminating it becomes extremely difficult.
Rabies is preventable even after an exposure, provided treatment is started promptly and before symptoms develop. Post-exposure prophylaxis, or PEP, generally includes thorough wound cleaning, rabies immune globulin for people who have never previously been vaccinated, and a course of rabies vaccine.
This is why North Carolina officials are not telling exposed visitors to wait for symptoms. Instead, NCDHHS says people who had contact with the goats should contact their local health department to determine whether medication is needed.
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