Pakistan continues to be dealing with a polio outbreak as four fresh cases have emerged, pushing the national tally to 37 this year, according to health officials on October 19, 2024. Health officials said that the regional reference laboratory for polio eradication at the National Institute of Health in Islamabad confirmed wild poliovirus type-1 (WPV1) in two children-one from each Balochistan and Khyber-Pakhtunkhwa.

In recent cases, a girl has been affected from Pishin, and two boys from Chaman and Noshki of Balochistan, and a girl from Lakki Marwat in KP. These are the first detections of the virus within Noshki and Lakki Marwat this year; isolated cases of poliovirus were previously reported within Chaman and Pishin. The province of Balochistan was the worst hit with 20 cases, Sindh had 10, Khyber Pakhtunkhwa had five, and Punjab and Islamabad had one case each.

A gigantic fight against polio has been on going in Pakistan- especially in Balochistan and southern KP-over the last two years. Immunisation campaigns have often been suspended or delayed because of local protests, insecurity, and community boycotts. Consequently, quite a number of children did not get the necessary vaccinations, making existing patches of vulnerability for the virus to flow within those pockets.

Noshki, located near Afghanistan's border, and Lakki Marwat have also recently reported some positive environmental samples that confirm the virus is present here, said a local reference laboratory official. Samples of latest cases are currently under genetic sequencing for checking spread of virus and origin.

As the threat of polio continues to grow, Pakistan has vowed to mount a nationwide campaign against it beginning from October 28. With the zeal to tackle the menace in the most effective manner, over 45 million children under the age of five will be vaccinated across the country.

Today, Afghanistan and Pakistan remain one of the few countries where polio has not yet been eradicated. The WHO said the virus remains a potential serious public health threat in areas with low vaccination coverage and weak surveillance.

India On Alert Against Polio

The country declared itself polio-free since 2014 and has kept the disease on bay almost a decade with very robust vaccination programs; however, two cases of vaccine-derived poliovirus cases reported in recent days from Meghalaya create some amount of doubts over a possible resurgence. Experts observe that in India, despite these detections taking place, strong coverage of vaccination at 90-95% and mandatory surveillance measures keep the risk of this widespread outbreak at bay.

The experts point out, however, that such stable situation in India requires continued surveillance. "Countries like Pakistan and parts of Africa remain at a high risk because vaccination rates in those areas are much lower," Dr. Siddharth, public health expert, said. Vaccination is an indispensable act in order to avoid the spread of this incapacitating disease that manifests most importantly as a nervous system affliction leading to the paralysis of a long period.

With concerted efforts from health authorities, there is hope someday that the scourge of polio will be completely eradicated from the face of the earth and future generations will never suffer from its effects.

The US Food and Drug Administration (FDA) has approved updated COVID vaccines from Moderna, Pfizer-BioNTech and Novavax-Sanofi for the 2026-27 season, the companies said.

Four COVID vaccines have been approved for use in the US after an advisory panel recommended that the shots target the dominant XFG variant.

What Are The New COVID Vaccines?

Moderna: mNEXSPIKE and Spikevax

• Spikevax: Approved for people aged 6 months through 64 who have an underlying condition, and anyone aged 65 or older.
• mNEXSPIKE: Approved for people aged 12 through 64 who have an underlying condition, and anyone aged 65 or older.

Pfizer-BioNTech: Comirnaty

It is approved for:

• All adults aged 65 and older.
• People aged 5 through 64 who have a condition that raises their risk of severe illness.

Novavax-Sanofi: Nuvaxovid

• Nuvaxovid is the only protein-based COVID vaccine available in the US. It is approved for everyone aged 65 and older and for those aged 12 through 64 who have underlying conditions.

The vaccine targets the JN.1 strain.

When Will The Updated Shots Be Available?

All manufacturers had previously said they could make the updated shots in time for the 2026-27 immunization season, although Novavax could take longer to manufacture its vaccine.

The Donald Trump administration had shelved the universal COVID vaccine recommendation. It now recommends that everyone aged 6 months and older consult a healthcare provider before getting the shot.

In May, eight of the committee's nine experts voted in favor of targeting the XFG variant for the 2026-27 campaign.

For the 2025-26 season, the FDA had recommended that COVID shots target LP.8.1, a subvariant of the JN.1 strain. The CDC has yet to make an official recommendation for this year's vaccines.

Experts say the vaccines should begin reaching pharmacies and doctors' offices in September, CNN reported.

What Is The Current COVID Situation In The US?

The CDC's latest respiratory illness data, updated August 21, shows that national and regional COVID-19 activity is increasing, although overall acute respiratory illness causing people to seek healthcare remains very low.

Doctors have been reporting an increase in patients testing positive through the summer. But some physicians are noticing a change in how the illness is presenting.

Reports have emerged stating that COVID is resurfacing with new symptoms including nausea, vomiting and diarrhoea.

COVID-19-related visits to the emergency room are also increasing.

Recent reports from doctors in Georgia describe patients arriving with gastrointestinal symptoms alongside, or sometimes instead of, the more familiar respiratory symptoms.

Although these symptoms may seem unusual compared with the classic COVID presentation, nausea, vomiting and diarrhoea are not new symptoms of COVID-19.

The CDC has included nausea, vomiting and diarrhoea among the possible symptoms of COVID-19 for years.

Dr James Black, medical director of emergency services at Phoebe Putney Memorial Hospital in Albany, Georgia, said doctors are still seeing fever, cough and upper-respiratory symptoms, but added, “A lot of people are coming in with gastrointestinal symptoms - nausea, vomiting, diarrhea, sometimes to the point of mild dehydration.”

Even as the Ebola outbreak caused by the rare Bundibugyo Ebola virus continues to spread, a new case study has revealed a striking finding: the lesser-known virus can remain at very high levels in a patient’s throat.

Ebola viruses are primarily known to attack the vascular system, damaging blood vessel integrity and disrupting the body’s ability to clot. This can lead to severe fluid loss, organ failure and, in some cases, internal or external bleeding.

However, a case study of a 39-year-old American healthcare worker infected with Bundibugyo Ebola virus in the Democratic Republic of the Congo (DRC) found that his throat carried more than 10 times as much viral RNA as his blood.

The patient was later medically evacuated to Germany, where he received experimental treatment at a high-level isolation unit in Berlin.

Throat Carried 10 Times More Virus

On day five of illness, testing showed:

• Throat: About 90 million viral RNA copies/mL
• Blood plasma: About 7 million copies/mL
• Difference: The throat had more than 10 times the viral RNA found in blood.

The case was published in Nature Medicine by researchers from Charité – Universitätsmedizin Berlin, with collaborators including the CDC, US Department of State, Robert Koch Institute, Emory University and Congo’s Institut National de Recherche Biomédicale.

How Was He Exposed?

The healthcare worker had performed an ultrasound nine days before symptoms began.

Eight days before symptoms, he performed two surgeries using standard personal protective equipment and reported no specific high-risk exposure.

He voluntarily isolated himself when symptoms began. His early symptoms included:

• Severe muscle pain and malaise
• 38.9°C fever despite acetaminophen
• Positive pan-Ebola PCR on plasma by day two

By day three, he developed abdominal pain, vomiting, confusion and orthostatic symptoms.

Experimental Treatment Was Given

Bundibugyo Ebola virus has so far caused three recorded outbreaks, but there are currently no licensed vaccines or specific treatments for the disease.

The patient had received a dose of rVSV-ZEBOV 41 months earlier, but that vaccine targets the Zaire species.

He received the investigational antibody cocktail MBP134 on day four, along with a 200 mg loading dose of remdesivir off-label.

He reached Berlin on day five with thrombocytopenia, lymphopenia and elevated liver enzymes.

Viral RNA Cleared From Most Samples

By day 13, viral RNA was below detection levels in his:

• Plasma
• Throat
• Urine
• Stool

However, the virus was still detected in semen on day 20 but was gone by day 25. Three laboratories failed to culture live virus from throat, plasma or semen samples, the report said.

The researchers cautioned that this cannot be directly attributed to MBP134 because pre-treatment culture data were unavailable. The patient was discharged 22 days after symptom onset.

His Immune System Also Responded

Researchers found rising antibodies against the virus between days five and six, along with virus-specific IgM and IgA, suggesting that his own immune system mounted a response despite receiving monoclonal antibodies.

However, the researchers stressed that the case does not prove MBP134, remdesivir or their combination works. Larger studies are needed.

Congo Ebola Outbreak

Congo declared the outbreak in Ituri Province on May 15, 2026, followed by a WHO public health emergency of international concern two days later.

As of August 22, the ECDC reported:

• 5,514 confirmed cases
• 2,642 deaths
• 4,607 cases and 2,065 deaths in Ituri

The Cyclospora outbreak ongoing in the US since May this year has reached 17,180 cases, compared with 1,180 cases through August last year, according to the latest figures released by the Centers for Disease Control and Prevention (CDC).

The cases, reported across 48 states plus the District of Columbia, include two deaths, while 922 people have been hospitalized.

In addition, the CDC is investigating 11,844 additional cases that have not yet been laboratory-confirmed. The federal agency added that the true number of people sick with cyclosporiasis is likely higher because some people recover without medical care and are not tested for Cyclospora.

“Recent illnesses may not yet be reported due to the time it takes to identify and report Cyclospora cases. It can take about six weeks from the start of symptoms to when CDC receives the case information,” the CDC said.

Cyclospora Cases Expected To Dwindle

Historically, the cyclosporiasis season in the United States runs from May 1 through August 31, so cases should dwindle as summer ends, the CDC said.

The largest outbreak this summer was reported in Michigan. Last week, Michigan noted a 3% increase in cases, bringing the state's total to 14,277 cases.

Outbreak Linked To Iceberg Lettuce

The outbreak has been linked to iceberg lettuce, particularly lettuce produced by Taylor Farms de Mexico. The lettuce was sold at stores and at Taco Bell restaurants across the US before it was recalled.

Cyclosporiasis is caused by a parasite that spreads through food and water contaminated with infected human feces.

The Food and Drug Administration, which oversees food safety, has said it is “confident that all recalled iceberg lettuce related to this specific Cyclospora outbreak is off the market.”

While an average American reportedly eats about 18.3 pounds of lettuce each year, consumers purchased about 7.6 million fewer pounds of lettuce during the four weeks ending July 18 compared with the same period last year, according to The Wall Street Journal.

Is It Safe To Eat Lettuce Right Now?

Food safety experts noted that people can eat lettuce now, but should choose their greens wisely.

“Consumers should make informed choices rather than avoiding leafy greens altogether,” said Darin Detwiler, a professor at Northeastern University, Food & Wine reported.

Because the recalls so far are tied to specific products from one producer and have not expanded to include other lettuce producers, other products are likely OK, Detwiler said.

“Consumers should follow FDA and CDC recall information rather than assuming every leafy green product is unsafe,” he said.

Wade Syers, an extension specialist for food safety at Michigan State University Extension, said the ongoing Cyclospora investigation “does not mean all lettuce or all leafy greens are unsafe.”

How To Prevent Cyclospora Infection

To reduce the risk of infection, the CDC recommends:

• Wash your hands before handling food.
• Wash fresh produce under running water before eating, preparing or cooking it.
• Cook food to at least 158°F (70°C) to kill Cyclospora.
• Follow CDC and FDA recall notices and avoid recalled products.
• Avoid bagged salad mixes.