Pakistan continues to be dealing with a polio outbreak as four fresh cases have emerged, pushing the national tally to 37 this year, according to health officials on October 19, 2024. Health officials said that the regional reference laboratory for polio eradication at the National Institute of Health in Islamabad confirmed wild poliovirus type-1 (WPV1) in two children-one from each Balochistan and Khyber-Pakhtunkhwa.

In recent cases, a girl has been affected from Pishin, and two boys from Chaman and Noshki of Balochistan, and a girl from Lakki Marwat in KP. These are the first detections of the virus within Noshki and Lakki Marwat this year; isolated cases of poliovirus were previously reported within Chaman and Pishin. The province of Balochistan was the worst hit with 20 cases, Sindh had 10, Khyber Pakhtunkhwa had five, and Punjab and Islamabad had one case each.

A gigantic fight against polio has been on going in Pakistan- especially in Balochistan and southern KP-over the last two years. Immunisation campaigns have often been suspended or delayed because of local protests, insecurity, and community boycotts. Consequently, quite a number of children did not get the necessary vaccinations, making existing patches of vulnerability for the virus to flow within those pockets.

Noshki, located near Afghanistan's border, and Lakki Marwat have also recently reported some positive environmental samples that confirm the virus is present here, said a local reference laboratory official. Samples of latest cases are currently under genetic sequencing for checking spread of virus and origin.

As the threat of polio continues to grow, Pakistan has vowed to mount a nationwide campaign against it beginning from October 28. With the zeal to tackle the menace in the most effective manner, over 45 million children under the age of five will be vaccinated across the country.

Today, Afghanistan and Pakistan remain one of the few countries where polio has not yet been eradicated. The WHO said the virus remains a potential serious public health threat in areas with low vaccination coverage and weak surveillance.

India On Alert Against Polio

The country declared itself polio-free since 2014 and has kept the disease on bay almost a decade with very robust vaccination programs; however, two cases of vaccine-derived poliovirus cases reported in recent days from Meghalaya create some amount of doubts over a possible resurgence. Experts observe that in India, despite these detections taking place, strong coverage of vaccination at 90-95% and mandatory surveillance measures keep the risk of this widespread outbreak at bay.

The experts point out, however, that such stable situation in India requires continued surveillance. "Countries like Pakistan and parts of Africa remain at a high risk because vaccination rates in those areas are much lower," Dr. Siddharth, public health expert, said. Vaccination is an indispensable act in order to avoid the spread of this incapacitating disease that manifests most importantly as a nervous system affliction leading to the paralysis of a long period.

With concerted efforts from health authorities, there is hope someday that the scourge of polio will be completely eradicated from the face of the earth and future generations will never suffer from its effects.

The UK government has confirmed a case of hantavirus infection in Tristan da Cunha, a remote British Overseas Territory in the South Atlantic Ocean, World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus has said.

In a post on social media platform X, Tedros said the patient had previously been classified as a probable case and had been exposed aboard the MV Hondius.

“As of June 10, the total number of confirmed cases remains 13, including three deaths,” he said. “No new deaths have been reported since May 2,” when a cluster of severe respiratory illnesses linked to the Dutch-flagged cruise ship MV Hondius was reported to the WHO.

While the outbreak aboard the luxury vessel had raised concerns about wider transmission. However, the WHO has assessed the overall risk to the public as low. The global health body recommended active health monitoring for all evacuated passengers for 42 days from their last exposure date, either in designated quarantine facilities or at home. The monitoring period is scheduled to continue until June 21.

The outbreak, which claimed three lives and infected 13 people, was driven by the Andes strain, which carries a risk of human-to-human transmission. There is currently no specific antiviral drug or vaccine for the Andes virus.

Study Suggests Potential Treatment

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A recent study published in The Lancet Infectious Diseases reported early promising results for tocilizumab as a treatment for severe hantavirus pulmonary syndrome (HPS).

The study is based on a case series involving 10 hantavirus patients treated at Hospital Zonal de Bariloche, Argentina, between June 1, 2024, and May 6, 2026.

Tocilizumab is an immunosuppressive medication used to treat severe inflammatory conditions, including severe COVID-19 and autoimmune diseases such as rheumatoid arthritis.

Researchers from San Carlos de Bariloche, Argentina, said that under an ethical framework allowing the emergency use of unproven medications outside clinical trials when no satisfactory alternatives exist, tocilizumab was administered to five eligible patients with laboratory-confirmed severe hantavirus pulmonary syndrome.

Five other patients received standard supportive care without tocilizumab because they were too sick or the medication was unavailable when treatment was being considered. The researchers said tocilizumab warrants further evaluation as a treatment for severe hantavirus pulmonary syndrome.

What Is Hantavirus?

According to the WHO, hantaviruses are zoonotic viruses that naturally infect rodents and are occasionally transmitted to humans.

Globally, an estimated 100,000 to 200,000 hantavirus infections occur each year. The majority of these cases are in Asia, particularly China. Most are sporadic or occur in small clusters linked to contact with infected rodents.

Infection in people can result in severe illness and often death, although the diseases vary by type of virus and geographical location.

The WHO has confirmed that the Andes strain of hantavirus—the only strain known to spread from person to person—is responsible for the outbreak. There is currently no vaccine available for the strain.

Notably, the WHO has not specified the type of hantavirus or syndrome involved in the cruise ship incident, but it did mention respiratory risks.

How Does Hantavirus Spread?

Hantavirus is primarily spread by rodents through:

• Exposure to rodent urine
• Exposure to rodent droppings
• Exposure to rodent saliva
• Less commonly, through a rodent scratch or bite.

Two orphaned babies have died of Ebola in the Democratic Republic of Congo, in an outbreak that could rival the worst on record.

Baby Buswaza was brought to a church-run orphanage in eastern Congo after her mother died in late May. The newborn was running a fever and, within days, died from what was later found to be Ebola, Reuters reported.

Buswaza was buried in late May in a sealed, waterproof body bag to prevent the spread of the disease.

More Suspected Cases at Orphanage

Six more babies have been identified as suspected Ebola cases at the orphanage of 69 children in Bunia, a city in Ituri province at the epicentre of the outbreak in Congo.

They were taken to hospital, where five of them later tested negative and were discharged from an isolation tent at the Evangelical Medical Centre (CME) by medics.

Another baby—an orphaned triplet girl nicknamed "Cherie" or "darling" who was less than a year old—with confirmed Ebola died on June 10, Dr. Freddy Kibwana, head of the CME, told Reuters. "The child has left us," he said.

How Children Can Be at Risk of Ebola

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Children and babies can easily become vectors for the disease through bodily fluids like vomit, faeces and saliva, which are highly infectious when people have Ebola.

"This epidemic has hit an area already in humanitarian crisis," said Babou Rukengeza, a senior health adviser with Save the Children aid group. "This place is the only refuge for these children."

“This outbreak is moving at a terrifying speed. I have responded to several Ebola outbreaks over the years, but this is the fastest spread I have ever seen. Children are paying a devastating price," he added.

The expert noted that “when parents die, children suddenly lose the biggest support system they could possibly have and face fear, grief, stigma, and social exclusion".

Can Ebola Be Passed From Mother to Child?

In addition to fluids like blood and saliva, Ebola has also been detected in amniotic fluid and the placenta, as per the World Health Organization, so it is possible Buswaza's mother transmitted the virus to her in the womb or during childbirth.

If the mother caught the virus after giving birth, she may also have transmitted it to her child through breastmilk, where the virus has also been detected.

Ebola Cases And Death Toll Climb

According to the US CDC, the confirmed cases in Congo have risen to 635, while there are 127 confirmed deaths. In Uganda, there are 19 confirmed cases and two confirmed deaths, along with one probable case and one probable death.

Using genetic fingerprinting, the illnesses have been identified as Bundibugyo virus, one of the four types of orthoebolaviruses that cause Ebola disease in people. There is no vaccine for Bundibugyo virus, and treatment consists of supportive care.

Ebola Outbreak: WHO Raises Risk Assessment

Meanwhile, the WHO has revised the risk assessment in Congo and Uganda. The risk has been revised to “very high at the national level in DRC and high for Uganda,” the WHO said.

It is also high for countries sharing land borders with DRC and Uganda, while low for the rest of the Africa region and at the global level.

The WHO explained that the risk in DRC remains very high because “the outbreak has continued to expand rapidly in terms of numbers of cases and geographical spread with more areas affected. Epidemiological links and the full chain of transmission are not yet clearly established, and the source of the outbreak remains under investigation”.

Moreover, the ongoing conflict is restricting movement of frontline responders and surveillance teams, while community fear and misinformation are hindering case detection, contact tracing and isolation, and potentially facilitating disease spread.

There are also other challenges such as limited healthcare infrastructure and delays in laboratory confirmation, although these are being scaled up by DRC with support from partners, the WHO said.

Health authorities in Kerala have reported a positive case of Nipah virus infection in a man from Kozhikode, triggering precautionary measures across the district.

The patient tested positive in a preliminary test conducted in Kozhikode and is currently undergoing treatment at Kozhikode Medical College Hospital, officials said.

With the fresh scare, health authorities have initiated extensive contact tracing and surveillance measures to prevent any potential spread of the infection.

According to officials, the patient arrived at the hospital through the outpatient department and is believed to have interacted with several people before being identified as a suspected Nipah case.

While the initial test indicated the presence of the virus, confirmation from a specialized virology laboratory is still awaited. Despite the pending confirmatory result, the state government has activated containment protocols as a precaution. Close contacts of the patient are being identified, monitored, and assessed as part of the standard public health response.

Kerala Health Minister Says No Need for Panic

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Kerala Health Minister K. Muralidharan said the patient had extensive contacts but stressed that there was no reason for panic at this stage. The minister noted that the patient had visited multiple departments of the private hospital where he first sought treatment, raising concerns about possible exposure to others.

As a precautionary measure, hospital staff who may have come into contact with the patient have been asked to undergo quarantine and monitoring.

What Is Nipah Virus?

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According to the World Health Organization, Nipah virus is a zoonotic disease, meaning it can spread from animals to humans. It can also be transmitted through contaminated food and, in some cases, directly from person to person.

In humans, Nipah infection can range from asymptomatic illness to severe respiratory disease and fatal encephalitis (brain inflammation). The virus can also infect animals such as pigs, causing significant economic losses for farmers.

Although only a limited number of outbreaks have been reported in Asia, the virus is known for its high fatality rate and potential to cause severe disease.

How Does Nipah Spread?

• Animal-to-Human Transmission: During the first recognized outbreak in Malaysia, which also affected Singapore, most human infections were linked to direct contact with infected pigs or their contaminated tissues. Transmission was believed to occur through exposure to respiratory secretions or bodily fluids of infected animals.

• Bat-Contaminated Food: In later outbreaks in Bangladesh and India, the most likely source of infection was the consumption of fruits or fruit products—particularly raw date palm sap—contaminated by saliva or urine from infected fruit bats.

• Human-to-Human Transmission: Human-to-human transmission has also been documented, particularly among family members and healthcare workers caring for infected patients.

Nipah Virus: Symptoms

Symptoms of Nipah virus infection may include:

• Fever
• Headache
• Breathing difficulties
• Cough and sore throat
• Diarrhea
• Vomiting
• Muscle pain
• Severe weakness
• Dizziness
• Altered consciousness in severe cases
• Encephalitis (brain inflammation)

Why Is Nipah A Concern?

Nipah virus is considered a major public health threat because of its high mortality rate, ability to spread through close contact, and the absence of a specific antiviral treatment or approved vaccine for widespread use.

Early detection, isolation of suspected cases, contact tracing, and strict infection-control measures remain the most effective tools for preventing outbreaks.