(Credit-Canva)
The current measles outbreak has gripped US states like Texas and New Mexico leaving people worried whether it would become a new pandemic. According to the Texas Department of State Health Services as of February 21, 90 cases were diagnosed in the last month in the South Plains area, with at least 77 of them were reported in children and teens under 17.
Measles is highly contagious and can be deadly. The outbreak, which started spreading in late January, has resulted in multiple hospitalizations, with at least nine confirmed cases and three probable cases as of early February. Health officials caution that at least one in five infected individuals will have to be hospitalized, highlighting the severity of the situation.
Misinformation surrounding vaccines and with the new Trump administration anti-vaccine campaigs, has causing parents to hesitate or refuse vaccination.
Furthermore, the country down under Australia is also witnessing a surge in measles cases as health officials in Sydney have issued an urgent alert, urging residents to watch for measles symptoms after an infected individual visited several places in Sydney over the last seven days.
Authorities report that the traveller had returned from South East Asia where there are ongoing outbreaks of measles.
Key symptoms of measles include fever, a runny nose, sore eyes, and a cough. Typically, a red, blotchy rash appears three to four days later, spreading from the head down to the body. Symptoms can manifest between 7 and 18 days after exposure.
Anyone who experiences these symptoms after potential exposure should immediately contact their doctor or emergency department. It is crucial to call ahead before visiting to avoid potentially exposing others in the waiting room. Dr. Selvey also highlighted that ongoing measles outbreaks are occurring in various parts of the world, making awareness and prompt action essential.
According to CDC everyone should get the MMR vaccine. It protects you from measles, mumps, and rubella. Getting vaccinated helps stop these diseases from spreading. There are two safe MMR vaccines available. They work the same way, so it doesn't matter which one you get. Kids can also get a shot that protects against chickenpox too, but this is only for children.
All children should get two MMR shots. The first shot should be given when they are between 12 and 15 months old. The second shot should be given when they are between 4 and 6 years old. If needed, the second shot can be given earlier, but it must be at least 28 days after the first shot.
Students going to college or other schools after high school, need two shots if they are not already immune. The shots must be at least 28 days apart.
Most adults need at least one MMR shot. Some adults need two shots, especially those who work in healthcare, travel a lot, or go to college. These people should get two shots, with 28 days between them.
Anyone traveling to other countries should make sure they are protected. Babies 6 to 11 months old should get one shot before traveling. Kids 12 months and older, teens, and adults need two shots, with 28 days between them.
People who work in healthcare should have proof that they are immune to measles, mumps, and rubella. If they are not immune, they need two MMR shots, spaced 28 days apart.
Women who might get pregnant should talk to their doctor about the MMR vaccine. It's safe to get the shot while breastfeeding.
Credit: X
A wearable device developed by Zomato founder Deepinder Goyal has sparked a massive social media debate among doctors over its scientific claims and validity.
Called Temple, the gadget, worn on the forehead, is designed to track physiological signals linked with blood flow in the brain and generate a metric called 'Entropy', which, according to Goyal, is a measure of the body's real-time energy expenditure.
Priced at Rs 85,000, one of the factors that has sparked arguments, the device is now available pre-orders in India. However, medical experts have questioned whether the technology can accurately measure what it claims to and whether its readings offer meaningful insights into brain health, ageing or longevity.
The controversy intensified after Goyal defended the project against criticism from doctors. In a post on X, he said the development had cost $30 million, including $20 million of his personal money. He also said further research was underway.
“We have a number of new research breakthroughs coming up (especially Entropy), and are validating them as we speak,” Goyal wrote on November 6.
Also read: This Easily Available Nutrient Can Also Slow Down Ageing
One of the main concerns is the device's sensor placement. Temple uses optical sensors based on photoplethysmography (PPG), positioned near the temple. These detect changes in blood flow through superficial blood vessels.
However, the superficial temporal artery supplies blood to the scalp and face. The brain receives its blood supply primarily through the internal carotid and vertebral arteries. A signal detected from a superficial vessel cannot automatically be interpreted as a measurement of blood circulation inside the brain.
Dr. Cyriac Abby Philips, widely known online as The Liver Doc, is one of the many doctors who challenged Goyal's claims about Temple on social media post.
He wrote, "Deepinder's Temple device is very much like Baba Ramdev's Coronil. Only one difference. Former is scienceploitation, latter is pseudoscience and both are harmful in their own ways. Learn to identify a scam and fraud when you see one."
Dr Jason Philip, in an X post, called the research behind the device "pseudoscience". He said that the gravity ageing hypothesis is a flawed concept. Ageing is a result of many factors like metabolic factors, genomic instability, mitochondrial dysfunction, chronic inflammation and more.
Many also slammed Goyal for selling the device without solid research or clinical outcomes.
Dr Rishabh Jain responded to Goyal's post, saying that doctors asking for scientific evidence is a legitimate demand. He also said that Goyal's response to clinical questions are mostly commerce-based and does not "constitute scientific validation".
Dr Kapil Singhal, Director of Neurology at the Institute of Neurosciences, Medanta, Noida, told Mint, “Temple appears to be measuring blood flow in the superficial temporal artery, which supplies blood to the scalp, not the brain. The brain receives blood through the internal carotid and vertebral arteries. These are not the same.”
Dr Praveen Gupta, Chairman of Marengo Asia International Institute of Neuro & Spine, Gurugram, also cautioned against treating a reading from one location as representative of the entire brain.
A device may detect physiological changes near the forehead but establishing that these reflect cerebral blood flow requires comparison with established clinical measurements and independent validation.
Also read: Mental Health And Longevity: The Mind-Body Connection To Aging Gracefully
Goyal has described Entropy as a new biomarker that measures how hard the body is working to sustain itself. The score is influenced by factors like sleep, exercise, stress, food and meditation.
However, doctors say that a metric responding to changes in activity does not establish what biological function it measures.
Neurologist Dr Sudhir Kumar told India Today that the idea was interesting but required stronger evidence.
“The idea of developing a novel physiological metric from signals recorded over the temple region is certainly intriguing, and advances in wearable technology have the potential to improve our understanding of human physiology. However, extraordinary claims require extraordinary evidence,” he said.
He added, “The key questions are not whether the signal changes with exercise, stress, or meditation, but whether it reliably measures what it claims to measure, whether it adds information beyond existing metrics, and whether acting on it improves health outcomes.”
In other words, doctors want to know how Entropy is calculated, what it represents biologically and whether it has been independently shown to improve health outcomes.
Temple is also associated with Goyal's Gravity Ageing Hypothesis which proposes that gravity and prolonged periods spent upright may affect blood circulation to the brain and contribute to ageing.
However, the brain has a mechanism called cerebral autoregulation that helps maintain relatively stable blood flow despite changes in posture and blood pressure.
Dr Gupta told The Indian Express, “The brain automatically adjusts the size of its blood vessels and regulates blood supply to ensure that it continues to receive enough oxygen and nutrients, even when we change positions, stand up or exercise.”
He added that there is no established scientific evidence that everyday exposure to gravity progressively damages the brain or accelerates ageing.
Goyal has said that Temple is a wellness and research product rather than a medical device. He has also argued that its claims will be independently verifiable and that more research will be shared soon.
However, doctors say the difference between detecting a physiological signal and demonstrating its clinical significance is crucial. Temple's ability to track certain readings would not, by itself, establish that it can diagnose neurological conditions, predict cognitive decline or measure longevity.
Credit: iStock
Kidney cancer, often considered as a disease associated with older adults, has been increasing in people under 50, according to latest data released by NHS England. The data shows that diagnoses in people under 50 have increased in one year as the number of cases in this age group increased by 12% between 2023 and 2024, prompting experts to highlight symptoms that can easily be mistaken for less serious health problems.
According to the figures, 1,227 people under 50 were diagnosed with kidney cancer in 2024, compared to 1,095 in 2023. Although kidney cancer remains more common in older adults, the increase sparks concerns about recognising early warning signs in younger people.
A study published in BJC Reports, which analysed more than 200,000 kidney cancer cases in England between 1985 and 2020, found that incidence among people under 50 had increased substantially. The rise was 157% among men and 133% among women.
Researchers said some of the increase may be linked to certain changing risk factors, including rising obesity rates, but other explanations still remain unclear.
One challenge is that kidney cancer may not cause obvious symptoms in its early stages. When symptoms do appear, they can resemble common conditions like muscle strain, urinary infections or other causes of back pain.
Andrew Greaves, general manager of Kidney Cancer UK, told the Daily Mail, “It’s very easy to miss, notoriously so.”
Back or side pain, chronic fatigue and night sweats are among the symptoms that can be overlooked. Greaves said around a third of patients report pain in the back, side or flank before diagnosis, while approximately one in four experience persistent fatigue and one in six report night sweats.
Blood in the urine, also known as haematuria, is one of the key warning signs. Greaves said that these symptoms are not limited to cancer. “Even if you said, I’ve got all four of those symptoms, it could still be highly unlikely that it’s kidney cancer, but it might be.”
According to the NHS, kidney cancer may cause:
Kidney cancer can sometimes be discovered incidentally when a person undergoes screening for another health problem. This can make diagnosis challenging because early-stage disease may present few or no symptoms.
Greaves said that more than half of kidney cancers are now found during scans conducted for other reasons.
He also explained that kidney cancer is often diagnosed late as symptoms are initially attributed to other medical conditions. Around a quarter of patients surveyed by Kidney Cancer UK said they had initially been treated for another condition before getting diagnosed with kidney cancer.
Credit: AI
An experimental bird flu vaccine designed by researchers using artificial intelligence (AI) has shown significant promise. It provided complete protection against multiple virus variants in animal-based trials. It outperformed existing vaccines stockpiled by governments for a human outbreak.
Developed by researchers at the University of Cambridge and its spin-off company DIOSynVax, the broad-spectrum vaccine protected mice and ferrets against various variants of bird flu virus that were genetically diverse. In comparison, the existing vaccine used in the study protected only around 50% of the animals exposed to the same variants.
The findings were published in the journal Cell Reports Medicine recently. The researchers say the findings could help improve preparedness for future influenza outbreaks. The vaccine is yet to be tested in humans.
“Rather than providing immunity to a single variant of bird flu, our new broad-spectrum vaccine is protective against a huge range of variants. It’s designed to counteract viral evolution, rather than reacting to it,” said Professor Jonathan Heeney, who led the research at the University of Cambridge's Department of Veterinary Medicine.
Also read: Bird Flu In Humans: 2 Cases, 1 Death In Washington; Experts Warn Of H5N1 Spread And Viral Evolution
Traditional vaccines often target specific virus strains that have already emerged and infected humans. However, influenza viruses can mutate rapidly, which could reduce the effectiveness of vaccines made for earlier variants.
The researchers collected genetic sequence data from bird flu viruses recorded through global surveillance programmes to tackle this challenge. These included samples from wildlife, livestock and infected humans.
They then used AI to analyse the large datasets and identify antigen features shared across different viruses. Antigens are the components of a vaccine that stimulate the immune system to identify and respond to a pathogen.
The researchers then used this information to design synthetic antigens, which were screened in laboratory tests before the most promising candidate was selected for animal trials.
“Using AI vastly speeds up the process of vaccine design, and then we can test the vaccine candidates in the lab to make sure they’re robust and safe,” Heeney said.
Dr Sneha Vishwanath, a member of the research team, explained that the vaccine's antigens were designed to target multiple stages of the virus's lifecycle. “By instructing the immune system to target different stages of the viral lifecycle, we can induce an immune response blocking several crucial steps in its replication,” she said.
Also read: AI-Created Virus Injected Into A Human For The First Time To Fight Antibiotic Resistance
The experimental bird flu vaccine provided complete protection to mice and ferrets that were exposed to various genetically diverse bird flu variants. These variants have all been linked with human infections and are considered major pandemic threats.
By comparison, only around 50% of the animals survived exposure when they were given the World Health Organization's existing bird flu vaccine.
The researchers said the findings suggest that a vaccine designed to target features shared across multiple virus variants could offer better protection than one developed against a particular strain.
The vaccine has only been tested in animal trials. Human clinical trials are the next step in the protocol. Its safety and effectiveness in people will need to be established before it can be considered for use.
Bird flu, also known as avian influenza, is an infectious disease caused by influenza viruses that primarily affect birds but can sometimes infect mammals, including humans. Some human infections can be mild while other variants have caused severe illness and deaths.
The researchers believe developing vaccines that protect against a wider range of variants could help reduce the risks posed by emerging infections.
“It’s when bird flu adapts to live in the airways of mammals that we start to get really nervous,” Heeney said. “If we can make better animal vaccines, then we can better protect human health as well.”
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