“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

As many as 125 doctors, nurses and public health professionals are contesting the November 3 US midterm elections, marking an unprecedented level of participation by healthcare professionals in electoral politics, according to a media report.

Among the prominent candidates are Dr Amy Acton, Dr Abdul El-Sayed and former US Health and Human Services (HHS) Secretary Xavier Becerra.

Many of these candidates entered the political spotlight during or after the COVID-19 pandemic. They are now seeking elected office to influence public health funding, vaccination policies, healthcare access, and the Trump administration’s approach to science and medical research.

“I haven’t seen anything exactly like this before,” historian Dr Kristoffer Shields, director of the Eagleton Center on the American Governor at Rutgers University, told CNN. “The link between science and politics has always been sort of weak.”

A separate review by Becker’s Hospital Review identified at least 58 physicians, nurses and other clinicians running for governor or Congress. The group includes 29 physicians, 16 nurses, four pharmacists, four dentists and five other healthcare professionals. Of these, 46 are contesting House seats, eight are running for the Senate and four are seeking governorships.

Few Healthcare Professionals In US Congress

Healthcare professionals currently remain a small minority in American politics. The US Senate has four doctors, all Republicans: John Barrasso of Wyoming, Bill Cassidy of Louisiana, Roger Marshall of Kansas and Rand Paul of Kentucky.

The House of Representatives includes 17 physicians, four dentists, two pharmacists, one nurse practitioner, one optometrist and one rehabilitation therapist.

Also read: EXCLUSIVE: Ex-CDC Vaccine Advisor Says Measles Outbreak Bigger Than Reported, Slams RFK Jr’s ‘No-See Evil’ Approach

Concerns Over Science and Public Health

Concerns about the Trump administration’s approach to science and public health have become a key reason for healthcare professionals to seek political office.

Other important concerns include the dismissal of federal doctors and scientists, cuts to research funding, removal of government datasets and public health websites, and changes affecting measures such as water fluoridation and childhood vaccination.

“Our country should be great. Our country should be pro-science, pro-innovation, and science keeps us safe. It protects us. It leads to wonderful discoveries, and this administration has completely burned all of that down,” Dr Kristin Hook, a former staffer at the National Institutes of Health (NIH) and the US Government Accountability Office, told CNN.

Hook, who lost her 2024 bid as a Democrat for Texas’ 21st Congressional District, is contesting the same seat again this year.

Becerra, contesting the California gubernatorial election against Republican candidate Steve Hilton, warned that weakening public health institutions could make the country more vulnerable to natural disasters and pandemics.

“HHS is not a place for science deniers or science skeptics. Why would you get rid of some of our best scientists and doctors and health professionals?” he told CNN.

Read More: CDC Survey Shows Nearly 3 In 4 American Adults Are Tired: Who Is Most Affected?

How COVID-19 Changed Health and Politics Equation

The COVID-19 pandemic brought public health officials into the political spotlight, as decisions on restrictions, vaccines and other health measures became subjects of intense public debate.

Some officials also faced threats and harassment, while others left their positions, prompting healthcare professionals to consider a more direct role in policymaking.

The death of Irish Olympic runner and European champion Ciara Mageean at the age of 34 has sparked concerns about bowel cancer among young people. In fact, Bowel Cancer Ireland has urged the national bowel cancer screening age to be lowered for early detection and prevention.

Mageean died on November 1, 2026 after being diagnosed with stage four bowel cancer in July 2025. The athlete had collaborated with Bowel Cancer Ireland after her diagnosis to spread awareness about the disease.

Bowel Cancer Risk In Young People

Around one in 10 bowel cancer diagnoses in Ireland occur in people under the age of 50. However, the country's national BowelScreen programme currently offers screening to people aged 57 to 71.

Brendan Donlon, chair of Bowel Cancer Ireland, told RTÉ's Morning Ireland that the screening age needs to be lowered and that the country must implement more policies to improve early detection.

"The death of Ms Mageean is a strong reminder that you can never be too fit or too young to be affected by bowel cancer," he said.

Donlon also spoke about the difference in screening ages in Ireland and other countries. He said the screening age was 45 in Australia, 50 in the UK and 45 in the US, compared with 57 in Ireland.

Although Ireland's Minister for Health has approved a recommendation to extend screening to people aged 50 to 54, Donlon said there was no clear timeline, budget or sufficient testing capacity to implement the change.

Also read: Olympian Ciara Mageean Dies At 34 After Bowel Cancer Battle: Warning Signs In Young Adults

Ireland Being Urged To Lower Its Bowel Cancer Screening Age

Bowel Cancer Ireland has been campaigning for earlier screening as cases among younger adults become an increasing concern. BowelScreen provides a free, at-home bowel screening test every two years to eligible people aged 57 to 71. The test is designed to detect signs of bowel cancer before symptoms develop.

In April 2026, Ireland's Minister for Health approved a recommendation to extend screening for people aged 50 to 54. However, the Health Service Executive (HSE) has said that the expansion depends on completing the current programme expansion and increasing healthcare capacity. The proposed timeline assumes implementation from 2031.

The expansion is expected to make more than 400,000 additional people eligible for screening and could require more than 2,700 additional colonoscopies each year.

Donlon said the availability of colonoscopy services was already a concern, pointing to 6,700 people who were waiting for urgent colonoscopy in the previous year. He also said that bowel cancer screening is essential as it can identify precancerous growths that can be removed before they develop into cancer.

He said, "It (bowel cancer) is a very survivable cancer. It's one of the most treatable cancers if caught early and unfortunately one of the most lethal when caught late. That's why we have to focus our attention on raising awareness of symptoms, but also getting the Government to focus on lowering the screening age."

Also read: IBS Is Not Just A Gut Problem: Lancet Review Explains The Gut-Brain Connection

Bowel Cancer Symptoms In Younger Adults May Be Overlooked

Bowel Cancer Ireland has urged people to recognise warning signs and seek medical advice rather than dismissing certain symptoms. According to Donlon, symptoms that should be assessed include:

• Blood in the stool, which may appear red or make stools look black
• Constant changes in bowel habits, including changes in stool consistency, size, shape or frequency
• Weight loss due to no reason
• Constant abdominal pain or bloating
• Tiredness that does not go away with rest or sleep

He advised people to seek medical attention if changes in bowel habits continue for three weeks.

He also raised concerns that symptoms in younger women may sometimes be attributed to premenstrual syndrome (PMS) or irritable bowel syndrome (IBS), which could delay further investigation.

"Unfortunately, most of the women in our group went to their GPs and particularly if they're under 50, they're told, you're fine, it's IBS, it's PMS, go away and come back," he told RTÉ.

Bowel cancer, also known as colorectal cancer, develops in the colon or rectum. It can often be treated successfully when detected at an early stage, but treatment becomes more difficult when the disease has spread to other parts of the body.

Screening is meant for people who do not have symptoms. Anyone experiencing possible warning signs should contact a healthcare professional rather than waiting until they become eligible for routine screening.

People who are battling anxiety may not be able to access anti-anxiety sold by Whole Foods, a popular brand in the United States. 365 Whole Foods Market Standardized + Full Spectrum Blend Ashwagandha Capsules by Vitality Works were voluntarily recalled recently over possible Salmonella contamination.

According to the Food & Drug Administration, manufacturers found the contamination during routine testing. The potentially contaminated drug has been on shelves since October 20 and will be available for purchase until November 24. Here is everything you need to know about the recall:

Which Product is Affected?

Ashwagandha is a popular herbal supplement widely used to help the body manage stress and anxiety.

The recall affects a specific batch of 365 Whole Foods Market Standardized + Full Spectrum Blend Ashwagandha Capsules (120-count size). The pills are sold on Amazon and at Whole Foods outlets. No illnesses have been reported due to the recalled pill so far.

To see if your bottle is part of the recall, check the bottom of the white plastic container for these specific details:

• Brand: 365 Whole Foods Market
• Product: Standardized + Full Spectrum Blend Ashwagandha Capsules, 120-count
• Lot Number: 2025-26227
• Expiration Date: 10/13/2028
• UPC: 9948252099

Also read: US FDA Recalls Thousands Of Blood Pressure Drugs Over Excess Drug Levels, Failed Quality Tests

Is Salmonella Dangerous?

Salmonella is a group of bacteria that can cause a foodborne illness called salmonellosis. While it is most commonly linked to contaminated foods like poultry, eggs, or unpasteurized milk, it can occasionally turn up in dry goods and medicines if raw ingredients are exposed to the bacteria during harvesting or processing.

When someone ingests salmonella, the bacteria irritate the lining of the intestines. Symptoms usually show up anywhere from six hours to six days after exposure. Salmonella infection may cause:

• Diarrhea (which can sometimes be bloody)
• Fever
• Stomach cramps and abdominal pain
• Nausea and vomiting

Most healthy people recover within a week without any medical treatment. However, the infection can be much more severe and occasionally dangerous for young children, older adults, and individuals with compromised immune systems.

The bacteria can occasionally enter the bloodstream and cause more severe infections. The CDC has warned that the actual number of infections may be higher than reported because some people recover without seeking medical care or getting tested.

Also read: Amgen & AstraZeneca's New Treatment Combination Cuts Advanced Lung Cancer Death Risk By 58% In Trial

What Should Consumers Do?

If you have a bottle of these ashwagandha capsules, take a quick look at the lot number. It is recommended to stop taking them immediately if they match the batch number that was recalled.

You could bring it back to the seller and get a refund by bringing your receipt. You could also discard the product safely in the trash if the seller does not accept returns.

If you have already taken these capsules and are feeling healthy, do not panic. Keep monitoring yourself for symptoms of infection. However, if you develop a sudden and persistent fever, severe stomach pain, or signs of a stomach bug in the days after ingesting the capsules, reach out to your healthcare provider.