“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

India's National Viral Hepatitis Control Program (NVHCP) has screened more than 210.6 million people and treated over 612,000 patients as of March 2026, according to the Ministry of Health and Family Welfare ahead of World Hepatitis Day 2026.

Viral hepatitis remains a major public health challenge. The World Health Organization (WHO) estimates that hepatitis caused 1.34 million deaths globally in 2015, a toll comparable to tuberculosis. In India, an estimated 40 million people live with Hepatitis B, while 6-12 million have Hepatitis C.

According to the 2021 HIV Sentinel Surveillance:

• 0.85% tested positive for Hepatitis B
• 0.29% tested positive for Hepatitis C

This is roughly equivalent to 1 in 118 people testing positive for Hepatitis B and 1 in 345 for Hepatitis C among those surveyed.

India's Plan to Eliminate Hepatitis

Launched in 2018, the National Viral Hepatitis Control Program aims to:

• Eliminate Hepatitis C by 2030
• Reduce infections, illness and deaths caused by Hepatitis B and C
• Prevent complications such as cirrhosis and liver cancer
• Reduce the burden of Hepatitis A and E

"Since 2018, India's National Viral Hepatitis Control Program has offered free screening and treatment for Hepatitis B and C nationwide. Smart use of local funding, cheaper generic drugs, and existing health programs has helped expand this care further," the government said in an official statement.

"Services are now moving from district hospitals down to local health centers, bringing testing and treatment closer to everyone," it added.

How Does It Work?

• Covers Hepatitis A, B, C, D and E
• Free testing and medicines for Hepatitis B and C
• Digital patient monitoring through the NVHCP-MIS portal
• Focus on prevention, awareness, screening and treatment
• The NVHCP is integrated with several health programs to expand access to prevention and care.
• Universal screening of pregnant women for Hepatitis B
• Hepatitis B birth dose for every newborn
• HBIG for infants born to Hepatitis B-positive mothers within 24 hours
• Screening of high-risk groups for Hepatitis B and C
• Hepatitis B vaccination for healthcare workers and eligible high-risk groups
• Uses existing TB molecular testing machines for hepatitis diagnosis
• Refers Hepatitis B and C-positive blood donors for treatment

What Is Hepatitis?

Hepatitis is inflammation of the liver caused by viruses, alcohol, certain drugs, toxins, or autoimmune diseases. Hepatitis B and C are the most common causes of chronic liver disease and can lead to cirrhosis and liver cancer if left untreated.

World Hepatitis Day 2026

World Hepatitis Day is observed each year on 28 July to raise awareness of viral hepatitis.

The World Hepatitis Day 2026 theme, “Hepatitis: Let’s break it down,” is a call to remove the barriers that stand between people and the services that can save their lives. Viral hepatitis continues to be a major cause of preventable illness and death worldwide.

Europe is battling an intense heatwave and fast-spreading wildfires, with soaring temperatures and prolonged dry conditions fueling blazes across the continent. France and Spain are among the hardest hit, with more than 360,000 people evacuated.

The crisis follows weeks of extreme heat, with temperatures exceeding 40°C (104°F) across several countries. A European Commission official said the wildfire season, which began in April, could last until early November. European Commissioner for Crisis Response Hadja Lahbib warned that wildfire damage this year could surpass previous records.

According to the World Health Organization (WHO), wildfires burned 2.2 million hectares across the WHO European Region last year, up from 1.4 million hectares in 2022.

"New data reveals a sharp rise in wildfires across parts of the WHO European Region between January and July this year. Portugal and Spain have seen reported wildfires increase by more than 100% compared with the same period in 2025," said Dr. Hans Kluge, WHO Regional Director for Europe.

France and Spain Bear the Brunt

France

• More than 250,000 people evacuated
• Fires on the Cap Ferret peninsula have burned over 42,000 hectares and spread toward Bordeaux.
• A rare fire thunderstorm in Gironde generated its own winds and lightning, making the blaze highly unpredictable.

The wildfire is "unlike any we have ever seen in France" because it is "following its own logic rather than any known pattern," said Nouvelle-Aquitaine prefect Sophie Brocas. "The fire is not over and remains extremely dangerous," she warned.

Spain

• More than 116,000 people evacuated
• Around 4,300 hectares burned in Castellón province.
• More than 153,000 hectares have burned nationwide this year.

Spain's meteorological agency Aemet warned that a new heatwave beginning July 29 is expected to last until at least August 2, with temperatures nearing or exceeding 40°C in several regions.

The agency also warned of a "significant or even extraordinary" fire risk, particularly for outdoor workers, older adults, and people with cardiovascular disease.

Belgium Worst Mortality Rate

Belgium recorded Europe's highest excess mortality during the late-June heatwave, according to EuroMOMO.

Data from Belgium's public health institute Sciensano showed more than 2,000 additional deaths, with excess mortality reaching 48%, compared with 23% in France and 13% in the Netherlands.

Canada Also Facing Severe Wildfires

Canada is also battling its own wildfire emergency after nearly 34,000 lightning strikes in a week ignited multiple fires across British Columbia. Authorities have issued 25 evacuation orders, while smoke has drifted into parts of the United States.

Climate Change Behind Extreme Fires

"As climate change drives a warming world, we need to prepare for more frequent and intense wildfires," said Dr. Hans Kluge.

He noted that Europe is the world's fastest-warming region, where heat has claimed more than 200,000 lives over the past four years, while heat-related deaths have increased by 30% over the past two decades.

What Are the Health Risks?

Extreme heat and wildfire smoke can seriously affect health, especially among:

• Older adults
• Children
• Pregnant women
• People with heart disease
• People with chronic lung conditions

"Smoke can travel long distances, worsening heart and respiratory conditions and affecting mental health. Fires can also disrupt access to healthcare and other public services," Kluge said.

Health Effects of Wildfire Smoke

Exposure to wildfire smoke can cause:

• Eye, nose, and throat irritation
• Persistent coughing and breathing difficulties
• Reduced lung function
• Bronchitis
• Asthma flare-ups
• Increased risk of heart attacks and strokes
• Premature death in severe cases

Fine particulate matter (PM2.5) can penetrate deep into the lungs and bloodstream, increasing the risk of long-term heart and lung disease.

WHO Safety Advice

The WHO recommends:

• Follow evacuation orders immediately.
• Limit outdoor activities when air quality is poor.
• Wear a well-fitting mask if exposure to smoke is unavoidable.
• Seek immediate medical attention if you experience chest pain, severe shortness of breath, or worsening respiratory symptoms.

A new study suggests that when you eat may be just as important as what you eat to support brain health as you age.

Researchers have found that restricting food intake to an 8 to 9-hour window each day and avoiding food for at least four hours before bedtime may help reduce age-related cognitive decline, particularly among older adults living with overweight or obesity.

The findings were presented at the American Society for Nutrition's NUTRITION 2026 annual meeting. The study supports the notion that fixed mealtimes could support healthy ageing beyond weight loss.

What Did The Study Find?

Led by researchers at Rutgers University, the study is based on 47 women aged 50 to 79 years who were overweight or obese.

All participants were enrolled in a six-month weight-loss programme and asked to consume 500 fewer calories per day. They were then divided into two groups:

Time-restricted eating group: Ate all meals within an 8 to 9-hour window, typically between 10 am and 6 pm.

Control group: Spread meals across a more conventional 12-hour eating window.

Both groups lost around 6.8 to 7 kg over six months. However, participants who followed the shorter eating window performed significantly better on tests assessing spatial planning, problem-solving, and executive function.

Researchers also noticed that they also committed fewer memory and learning errors.

Why Could Meal Timing Matter?

Also read: Scientists Say Changes In Brain In Your 40s & 50s May Influence Dementia Risk

Following fixed meal times can regulate the body's circadian rhythm, the internal biological clock that keeps sleep in check, metabolism, hormone release, and other essential brain functions.

Eating earlier in the day and avoiding late-night meals may improve metabolic health, reduce inflammation, enhance insulin sensitivity, and support healthier brain function over time. These factors are known to lower risk of cognitive decline.

Lead investigator Professor Sue Shapses, nutritional scientist at Rutgers University and Rutgers-RWJ Medical Center, said, "Losing weight alone will ward off some of the aging-related cognitive decline, and these data suggest that there may be additional benefits if you stop eating four hours before going to sleep and reduce food intake to 8 to 9 hours per day, compared with the usual eating window of 12 hours per day."

She added, "These outcomes suggest a better ability to remember information during everyday tasks and reducing mistakes related to memory, attention and problem-solving. Reductions in the eating window predicted greater improvements."

Can It Influence Dementia Risk?

Also read: Japanese PM Sanae Takaichi Sleeps 3 Hours A Night: How Much Sleep Do You Really Need?

The researchers stress that the study does not prove that a 9-hour eating window prevents dementia. Instead, it suggests that meal timing could become one of several lifestyle strategies to support cognitive health.

Dementia risk is influenced by multiple factors including age, genetics, obesity, diabetes, hypertension, physical activity, sleep, and diet. Time-restricted eating may eventually become part of a broader prevention approach if future research confirms these findings.

Dementia Risk Gets Influenced During Midlife

A recent study found that brain undergoes immune changes during 40s and 50s that could influence the risk of dementia.

Researchers found that the hippocampus, the brain region responsible for learning and memory, experiences a major shift in its immune cells during the 40s and 50s.

Once this immune environment changes, it may make the brain more vulnerable to inflammation and cognitive decline.

The findings suggest that this change could lead to chronic inflammation associated with Alzheimer's disease and other forms of dementia in the future .