“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

The US Centers for Disease Control and Prevention (CDC) has confirmed that the Salmonella outbreak that infected 34 people in 13 states in the country is linked to backyard poultry.

The CDC, in its latest report, noted that backyard poultry, like chickens and ducks, can carry Salmonella germs even if they look healthy and clean. To date, no deaths have been associated with this outbreak, which started on February 26 and lasted up to March 31. However, 13 people have been hospitalized, the federal agency said.

Notably, the CDC analysis revealed that the Salmonella strain may be resistant to the antibiotic fosfomycin. Samples from eight of those patients showed there could be resistance to other antibiotics commonly used in Salmonella infections.

States Reporting Salmonella Outbreak

Michigan has the most cases, with six, followed by Wisconsin and Ohio, each of which has five cases.

Indiana, Kentucky, and Maine each have three cases. Florida, Illinois, Mississippi, New Hampshire, and Tennessee have each confirmed a single case.

Children Under Age 5 More Affected

Forty-one percent of case-patients in this outbreak are under the age of 5 years, and of the 29 people interviewed by investigators, 23 (79%) reported contact with backyard poultry in the days prior to illness.

“Children younger than 5 years old shouldn't handle the birds (including chicks and ducklings) or anything in the area where the birds live and roam. They are more likely to get sick from Salmonella,” the CDC said.

“Of 14 people who reported owning backyard poultry, 13 (93%) bought or obtained poultry since January 1, 2026,” the CDC said. “People reported getting their poultry from various places, including agricultural retail stores.”

The CDC said it will continue to investigate the hatcheries associated with cases.

What Can You Do To Be Safe?

• Always wash your hands for 20 seconds after touching birds, their supplies, or collecting eggs.
• Use a pair of dedicated shoes or boots for your coop and don't wear them inside your house.
• Keep birds and supplies outside the house to prevent spreading germs into your house.
• Children younger than 5 years old shouldn't handle the birds (including chicks and ducklings) or anything in the area where the birds live and roam. They are more likely to get sick from Salmonella.

The CDC also advised businesses to

• Source poultry from hatcheries that take steps to reduce Salmonella contamination.
• Clean and sanitize poultry display areas between shipments of new poultry.
• Provide handwashing stations or hand sanitizers next to poultry display areas and tell customers to wash their hands right after leaving these areas.
• Display poultry out of reach of customers, especially chil­dren, so they cannot easily touch the poultry.

What is Salmonella?

As per the US Food and Drug Administration (FDA), Salmonella is a group of bacteria that can cause gastrointestinal illness and fever called salmonellosis. It can be spread by food handlers who do not wash their hands and/or the surfaces and tools they use between food preparation steps. It can also happen when people consume uncooked and raw food. Salmonella can also spread from animals to people.

The FDA notes that people who have direct contact with certain animals, including poultry and reptiles, can spread the bacteria from the animal to food if hand washing hygiene is not practiced.

Pets, too, could spread the bacteria within the home environment if they eat food contaminated with Salmonella.

Most people infected with Salmonella develop diarrhea, fever, and stomach cramps 6 hours to 6 days after being exposed to the bacteria.

The illness usually lasts 4 to 7 days, and most people recover without treatment.

In some people, the illness may be so severe that the patient is hospitalized.

Children younger than 5, adults 65 and older, and people with weakened immune systems are more likely to have severe illness.

US President Donald Trump-backed decision by the Centers for Disease Control and Prevention (CDC) to stop recommending giving infants a dose of the hepatitis B vaccine within 24 hours after birth is likely to lead to hundreds more infections, deaths, and millions of dollars in higher costs, according to new research.

The research, published in JAMA Pediatrics, comes as federal vaccine advisers to Health Secretary Robert F. Kennedy Jr. voted in December 2025 to reverse the long-standing recommendation to delay the first shot until at least two months of age for infants born to mothers who test negative for the virus.

While pediatricians, public health experts, and dozens of medical groups warned that it could harm children and their families, the new JAMA studies modelled the potential impact of the policy.

What Did The Studies Predict?

The first study estimated that delaying the first hepatitis B vaccine dose by two months for babies born in a single year to mothers who tested negative — about 80 percent of the 3.6 million US births annually — would increase lifetime health-care costs by at least $16 million, The Washington Post reported.

If vaccination were delayed by seven months, it would cost an additional $19.8 million.

The second study modeled what would happen if only 10 per cent of babies born to unscreened mothers received a birth dose; an additional 628 babies would get infected.

“One of the most concerning implications is how many more infected Hep B babies will we see,” said co-author Rachel Epstein, a pediatric and adult infectious diseases clinician at Boston Medical Center.

“A universal birth dose helps prevent a substantial number of infections in babies of a lifelong condition that we do not have a cure for,” she added.

CDC Had No evidence To Overturn Hepatitis B Vaccine Policy

Since 1991, all infants born in the US have received the first dose of hepatitis B vaccine within 24 hours of birth, a strategy that led to close to a 99 percent decline in infections among children.

Calling the universal birth-dose policy "a safety net", public health and medical experts noted that nearly 15 percent of pregnant women miss recommended hepatitis B screening. More than half of those who test positive do not receive appropriate follow-up care.

Delaying the initial dose also decreases the likelihood that a child will complete the three-shot series needed for full protection, hepatitis experts have said.

The authors argued that the CDC advisory panel departed from standards established for over three decades and failed to weigh key evidence.

“We noticed that the committee did not have the evidence they needed to inform their decision,” co-author Eric Hall, an assistant professor of epidemiology at Oregon Health and Science University, was quoted as saying to The Post.

“But this group kind of blew past all that and didn’t make any effort to fill the evidence gaps that they might have had. They just went ahead anyway.”

Also read: Hepatitis Infections Claims 1.3 Million Lives Worldwide, India Among Top Contributors: WHO

What is Hepatitis B?

Hepatitis B is a viral infection that affects the liver. It is highly contagious and spreads when blood, semen, or other bodily fluids from a person who carries the virus enter the body of someone who is not infected.

Hepatitis B can also pass from an infected mother to her baby during childbirth, whether through a vaginal delivery or a C-section. It is the most common route of transmission.

Vaccination is the most reliable way to prevent hepatitis B. The shots offer strong protection in infancy and continue to shield individuals well into adulthood.

Babies usually receive a three-dose series. A scientific review by the Vaccine Integrity Project found that 95 percent of healthy infants develop enough immunity after the third dose. The vaccine also lowers the risk of infection by nearly 70 percent in babies born to mothers who have hepatitis B.

A biryani feast followed by a serving of watermelon proved deadly for a family of four in Mumbai on Sunday. The incident was reported from the Pydhonie area, where an entire family passed away after eating biryani for dinner and some watermelon before calling it a night. They had watermelon around 1.00 am or 1.30 am, and their condition started to deteriorate around 5.00 am. They all experienced diarrhoea and nausea and eventually passed away. The mystery now remains: was it a case of accidental watermelon poisoning or something else? Abdullah Dokadia (40), his wife Nasreen Dokadia (35), and their two daughters, Ayesha (16) and Zainab (13), lost their lives, and the police are currently suspecting it to be a case of food poisoning. But can eating watermelon really kill you? Let us find out.

What are the signs of watermelon poisoning?

Watermelon is a popular summer fruit that people enjoy eating during the hotter months. It is 70 per cent water, highly hydrating, and also beneficial for weight loss. However, going overboard is discouraged by doctors, as overeating or consuming adulterated watermelon can lead to abdominal discomfort and digestive distress. Watermelon-related food poisoning can occur because of E. coli or salmonella infections. It can cause rapid dehydration, diarrhoea, cramps, fever, weakness, and, in extreme cases, even death.

What happens when you eat too much watermelon?

Dr Aarti Ullal, Physician and Diabetologist at Gleneagles Hospital, Parel, in an interaction with Health and Me, said, “Eating too much watermelon may lead to bloating, stomach discomfort, or loose motions, mainly because of its high water and natural sugar content. In some individuals, especially those with sensitive digestion, it can also cause acidity or mild cramps and disturb their peace of mind.”

Dr Ullal also stated that watermelon poisoning can occur when the fruit is contaminated with pesticides, chemicals, or bacteria due to poor handling or improper storage. The symptoms may include nausea, vomiting, abdominal pain, diarrhoea, and weakness. These are typically short-term digestive issues but may require medical attention if severe or if they interfere with daily routine. However, questions also arise regarding watermelon allergies. Watermelon allergy is rare and may cause itching in the mouth, swelling, rashes, or stomach upset soon after consumption.

How to check if your watermelon is adulterated?

To check if a watermelon is adulterated, look for an unnaturally bright red colour, cracks, a chemical smell, or an overly soft texture. Always wash the outer surface, as it may contain pesticides or chemicals, before cutting. Make sure to buy from trusted sources to avoid any health issues. Watermelon is safe and healthy to consume, but moderation and proper hygiene are key.

Can eating a watermelon kill you?

Conclusively, it can be said that eating a watermelon specifically should not cause deaths. However, if you bring the fruit home, it is advised to check it for signs of adulteration before consuming. It helps eliminate the possibility of side effects, just in case. However, if you experience food poisoning-like symptoms, consult a doctor immediately.