“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

Northern Ireland is set to restrict price promotions on unhealthy foods as part of its long-term strategy to curb rising obesity rates,

With this move, the country has joined the UK who has been making efforts to create healthier food environments.

The proposed policy is expected to limit promotions like multi-buy offers and other incentives on foods high in fat, salt and sugar (HFSS).

It could make healthier choices more accessible, reducing the influence of marketing on consumer behavior.

The policy forms part of Northern Ireland's Healthy Futures: Tackling Obesity strategy, which emphasizes prevention alongside better treatment services.

The Department of Health has recently announced the rollout of a Regional Obesity Management Service, but public health experts say clinical services alone will not reverse the obesity epidemic without stronger preventive policies.

Can This Policy Help?

Obesity remains one of Northern Ireland's biggest public health challenges. Around 65% of adults in Northern Ireland are overweight or living with obesity, while about one in four children are affected.

Excess weight significantly increases the risk of type 2 diabetes, heart disease, stroke, certain cancers and other chronic illnesses.

Policymakers and health advocates argue that supermarkets' rampant discounts and volume-based promotions on calorie-dense processed foods encourage unnecessary purchasing and higher consumption, particularly among families with constrained budgets.

Also read: Not Just The Heart, Obesity In Midlife Could Be Just As Harmful To The Brain: Study

Expectations From The Policy

The proposed restrictions are expected to target promotions on HFSS foods, including multi-buy deals such as "buy one, get one free", volume-based discounts, and other promotional tactics that encourage purchasing larger quantities of unhealthy foods.

The initiative complements broader UK policies that are already being implemented, including restrictions on junk food advertising before 9 p.m. on television and a ban on paid online advertising for unhealthy foods.

These measures aim to reduce children's exposure to unhealthy food marketing and encourage healthier eating habits.

Also read: Smoking, Diabetes, High Blood Pressure May Fuel the Most Dangerous Type of Artery Plaque, Study Finds

Reactions

Northern Ireland's plans have received strong backing from public health organizations and health advocates.

Fearghal McKinney, Head of the British Heart Foundation Northern Ireland, said, "While we welcome the announcement of the first phase of the obesity programme as a significant step forward to support people living with obesity, this alone does not go far enough in providing a long-term and multi-department government solution."

He added, "Obesity is a major risk factor for cardiovascular disease and a leading cause of the increasing number of deaths in Northern Ireland."

McKinney also said, "This announcement must be accompanied by urgent delivery of actions within the Healthy Futures obesity strategy, including publishing a consultation to restrict price promotions on unhealthy foods."

Across the UK, governments are increasingly focusing on reducing consumption of unhealthy food through marketing tactics rather than focusing on individual behavior change.

Announcing England's advertising restrictions, Health Minister Ashley Dalton said, "By restricting adverts for junk food before 9pm and banning paid adverts online, we can remove excessive exposure to unhealthy foods, making the healthy choice the easy choice for parents and children."

Northern Ireland's proposed promotion restrictions are still going through implementation stages, but health experts view them as positive step towards broader obesity prevention strategy.

Combined with better medical services, education and healthier food environments, policymakers hope the measures will reduce obesity rates, lower the burden of chronic disease and ease pressure on the healthcare system.

The World Health Organization (WHO) has warned that West Nile virus infections are increasing across parts of Europe, with hotter temperatures, longer summers, and changing weather patterns creating ideal conditions for mosquito-borne disease transmission.

The warning comes as Europe grapples with intense heatwaves and widespread wildfires, which experts say are contributing to the spread of disease-carrying mosquitoes.

Cases Rising Across Southern Europe

Greece has recorded the sharpest recent increase, with 21 confirmed human cases as of July 22, including 14 reported in the previous week alone.

Of these, 20 patients developed neuroinvasive disease, such as encephalitis or meningitis, and 13 remain hospitalized.

Italy has reported the widest geographic spread, with 21 confirmed cases across 17 different areas as of July 15. Locally acquired infections have also been reported in North Macedonia (2 cases), Romania (2), and Spain (2).

The WHO noted that while the risk remains low for most people, it may turn deadly for some.

"West Nile virus is not a new threat, but the conditions driving its spread are changing rapidly," said Dr. Hans Henri P. Kluge, WHO Regional Director for Europe.

“Most infections are mild, but roughly 1 in 150 people who contract the virus will develop a severe infection affecting the central nervous system, which can be life-threatening,” he added.

Kluge added that warmer temperatures and longer summers are giving mosquitoes more time and a wider geographic range to transmit the virus.

What Is West Nile Virus?

West Nile virus is spread primarily through the bite of an infected mosquito. Mosquitoes become infected after feeding on infected birds and can then transmit the virus to humans and other animals.

In Europe, infections typically occur during the mosquito season—from late spring through autumn—with transmission peaking between July and September.

Although rare, the virus has also been transmitted through blood transfusions, organ transplantation, pregnancy, and breastfeeding. There is no evidence of person-to-person transmission through everyday contact.

Currently, there is no licensed vaccine for humans and no specific antiviral treatment. Care focuses on relieving symptoms, while severe cases may require hospital-based supportive treatment.

Symptoms to Watch For

Around 70–80% of infected people develop no symptoms.

Those who do become ill may experience:

• Fever
• Headache
• Fatigue
• Body aches
• Nausea or vomiting
• Skin rash
• Swollen lymph nodes

In severe cases, the infection can affect the nervous system, causing:

• High fever
• Neck stiffness
• Disorientation
• Tremors
• Convulsions
• Muscle weakness
• Paralysis
• Coma

Anyone who develops symptoms after returning from an area where the virus is circulating should seek medical attention promptly. People with severe symptoms require urgent medical care.

West Nile virus infection can be confirmed through laboratory tests that detect virus-specific antibodies or viral RNA, depending on the stage of illness.

How to Protect Yourself

As there is no vaccine or specific treatment, WHO says prevention depends on avoiding mosquito bites and reducing mosquito breeding sites.

WHO recommends:

• Wear light-colored clothing that covers the arms and legs.
• Limit outdoor activities during dawn and dusk, when mosquitoes are most active.
• Apply mosquito repellents containing approved ingredients according to the manufacturer's instructions. Adults should apply repellent to young children and avoid the eyes, mouth, and hands.
• Install window and door screens to keep mosquitoes out of homes.
• Sleep in air-conditioned rooms, use fans, or sleep under mosquito nets where needed.
• Eliminate standing water from flowerpots, buckets, bird baths, clogged gutters, and other containers where mosquitoes can breed.

Israel’s military is facing an alarming mental health crisis as prolonged geopolitical conflict continues to take a psychological toll on its soldiers.

Recently, two female Israeli soldiers died by suicide within days of each other, bringing the number of active-duty military suicides this year to at least 16, according to Israeli media.

The deaths in the force have reignited concerns over whether the military personnel are receiving necessary trauma and mental health care

The latest cases involved a combat soldier from the Bardelas Battalion and an intelligence officer. Military Police have launched investigations, while the Israel Defense Forces (IDF) has acknowledged the incidents, saying that the affected units are being supported in every way.

Mental Health Crisis In Israel's Military

According to Israel’s Defence Ministry, cases of post-traumatic stress disorder (PTSD) among soldiers have increased by nearly 40% since 2023.

Of more than 22,000 personnel receiving treatment for war-related injuries, around 60% are being treated primarily for psychological trauma.

“Soldiers are grappling not only with fear for their own lives, but also with moral injury resulting from witnessing or participating in traumatic events,” clinical psychologist Ronen Sidi of Emek Medical Center told Reuters.

Also read: Many US Veterans With Suicidal Thoughts May Not Be Receiving Mental Health Treatment, Study Finds

What Is Moral Injury?

Unlike PTSD, which is often linked to fear-based traumatic experiences, moral injury refers to when patients feel they have violated deeply held moral or ethical beliefs, or witnessed events that violate those values.

Military psychologists say constant exposure to civilian casualties, loss of troops, and conflicting decisions on the battlefield can leave lasting emotional wounds that last for a long time.

Ground Reality

The two recent suicides are not isolated incidents. Earlier this year, Israeli media reported that many soldiers on active duty had taken their own lives after returning from their deployments.

Some reports also said that soldiers who were discharged are struggling with severe PTSD, depression and social isolation after leaving service. Researchers say many continue to battle mental health issues long after their duty ends.

Veterans’ organisations have increasingly called for comprehensive and effective rehabilitation services, saying that untreated trauma may surface months or even years after military service ends.

Also read: US Government Backs Psychedelic Therapies Research For Veterans With PTSD and Depression

Are Mental Health Support Systems Enough?

The Israeli Defence Ministry says it has expanded mental health services, funding and introduced alternative therapies to improve mental health recovery for soldiers who are struggling.

However, some recent reports have questioned whether those services are reaching troops quickly enough. Critics have pointed to shortages of field psychologists, cancelled mental health support days and unsuccessful recognition of warning signs.

Mental health specialists also say that stigma remains another barrier. Despite growing awareness, many soldiers hesitate to seek help because they believe that doing so could affect their careers or be viewed as a sign of weakness.

For Israel, the growing number of soldier suicides is becoming a stark reminder that the cost of war is measured not only in physical casualties, but also in the invisible wounds that reflect through mental health issues.