“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

Sri Lanka is facing a meningitis outbreak, and according to the Health Promotion Bureau of Sri Lanka, 200 people have been infected by this virus. As of now, about 50 people are getting treatment at the hospitals across four districts.

The disease was first found among a group of school goers in the Deniyaya area before spreading to other areas, including Diyatalawa, Welimada, and Rikillagaskada. The health authorities of the island nation have already issued special guidelines to stop the spread of the disease.

The authorities there said the disease mainly spreads through contaminated food and water, and it can also be transmitted through droplets released when an infected person coughs or sneezes, as well as through close contact. The citizens were also asked to drink boiled water and avoid crowded places.

The Health Ministry of Sri Lanka has appointed a special team consisting of virologists and epidemiologists to conduct observations on the viral meningitis condition reported from the Central and Southern provinces and to identify its viral transmission pattern.

“Though the cases show signs of meningitis, they have rarely progressed to encephalitis, a potentially life‑threatening inflammation of brain tissue, as the virus itself is self-limiting, allowing the immune system to overcome the ailment,” the deputy minister, Dr. Wijeyamuni, said.

What Is Meningitis?

Meningitis is an infection of the protective membranes around the spinal cord and the brain. It can become very serious if not treated or diagnosed in time. It is a consequence of bacterial or viral infection. Despite being a rare occurrence, the infection can spread through coughs, sneezes, a cold, or physical contact in the form of kissing.

Understanding the symptoms, causes, and treatment options is important for early diagnosis and timely medical care.

Also Read: Does Meningitis Always Cause Fever?

Symptoms Of Meningitis

Health officials urged the public to remain alert to the warning signs of meningococcal meningitis. Common symptoms include:

• Rash
• Headache
• Neck stiffness
• Fever
• Drowsiness
• Nausea or vomiting
• Increased sensitivity to light

How is Meningitis Diagnosed?

Physicians diagnose meningitis using a combination of clinical presentation, laboratory examinations, and imaging tests. Important diagnostic tests are Lumbar Puncture (Spinal Tap), Blood Cultures, and Imaging (CT or MRI Scans).

US President Donald Trump has declared himself to be in good health after undertaking the third annual medical check-up in his second term as the oldest American President.

Trump, who turns 80 next month, saw his doctors at the Walter Reed National Military Medical Center for a routine health check up on May 26.

“Everything checked out PERFECTLY,” Trump wrote on social media. He has, however, offered no details about what doctors observed.

The White House hasn't so far released details from Trump’s health check up to support his claim, or clarify what tests the president had undergone as part of the clinical exam.

As per an earlier statement from the White House, the visit involved “routine annual dental and medical assessments as part of his regular preventive health care,” but did not offer additional details on the medical exam.

His previous annual check-up was in April 2025. In October, he underwent another check-up.

“You have five doctors sitting there and … the questions are very easy at the beginning, then pretty easy, then pretty hard by the time you get to the end, there are not a lot of people in the room who can get them, believe me,” Trump informed the crowd at a rally in New York state last week about the impending test, The Times reported.

“So the first question was, you have a bear, a snake, an elephant, and a horse. Name the horse. That’s the horse. The second question is a little tougher,” he said.

“Toward the end, they had a question like, pick a number, sir, any number. OK. 203. Multiply times nine, divided by two, add 1324, subtract 1292. Sir, multiply it out one more time by 19. What is the answer, sir? I got it right … and the one doctor said, I’ve been doing this test for 20 years, I’ve never seen anybody ace it. … So I’ve taken it, and I’ve aced it all three times, I’ll tell you, because it is a positive thing.”

Trump In ‘Excellent Health’

Also read: ‘Sea Or See?’ Donald Trump's Remark Sparks Fresh Cognitive Health Speculation

The president’s health has been the subject of intense scrutiny — ranging from his mental state to visible bruising around his hands.

Trump — who has frequently criticized former President Joe Biden over age-related health and fitness issues — has recently remarked on how good he feels despite his age.

Trump said he feels the same as he did 50 years ago. “I feel literally the same,” he said at an Oval Office event. “I don’t know why. It’s not because I eat the best foods,” AP reported.

Read More: Russia's New Ebola Vaccine To Protect Against Rare Bundibugyo Strain, Says Health Minister

He also joked about his exercise regimen, saying that he works out “like about one minute a day, max.”

According to a White House summary of his previous annual medical examination in April last year, Trump was found to be in “excellent cognitive and physical health”.

“A comprehensive neurological examination revealed no abnormalities in his mental status, cranial nerves, motor and sensory functions, reflexes, gait, and balance. Cognitive function, assessed using the Montreal Cognitive Assessment (MoCA), was normal with a score of 30 out of 30,” his White House physician, Captain Sean Barbabella, wrote.

There were tests for depression and anxiety, and Trump recorded a score “within the normal range for both,” although numbers were not given.

Scans in October also demonstrated that Trump is in “excellent overall health”.

Amid the rising heatwave conditions in India, Prime Minister Narendra Modi today expressed his concerns and advised the citizens to stay hydrated.

In a post shared on the social media platform X, PM Modi asked people to take precautions as well as help fellow citizens by offering drinking water.

"Temperatures are continuously rising in different parts of the country, and along with this, the many difficulties caused by the heat in daily life are also increasing. I urge all my fellow citizens to take as many precautions as possible. Please keep yourselves hydrated and carry water with you when stepping out of your homes,” the Prime Minister said.

“In such weather, your sensitivity also becomes a great source of support. If possible, do offer a glass of water to anyone who is thirsty. I also appreciate those people who keep water in pitchers outside their homes and shops so that anyone can drink from them,” he added.

Temperatures Are Rising Throughout The Nation

The post comes as the temperature is increasing throughout the country.

According to the Indian Meteorological Department (IMD), the maximum temperature is expected to reach around 45°C on Wednesday, while the minimum may stay close to 28°C.

This extreme heat has become a serious public health challenge, as it affects everything from hydration levels in the body to digestion, the health of your skin, heart, and even mental well-being.

The department has issued a clear warning for a “heatwave.” Strong surface winds are also expected during the afternoon and evening. Humidity levels on May 27 are forecast to vary between 40 per cent at the highest and 25 per cent at the lowest.

Authorities have cautioned that the heatwave may be accompanied by strong, hot winds later in the day. People are advised to stay indoors during peak afternoon hours, remain hydrated, and take necessary measures to avoid direct exposure to sunlight.

Speaking to HealthandMe, Dr. L.K Jha, Associate Director & Head Unit-II– Cardiology, Asian Hospital, Faridabad, said how extreme heat levels can increase heart conditions such as palpitations.

“Dehydration contributes to palpitations associated with heatwaves significantly due to excessive sweating, fluid loss, and critical electrolyte loss, which all play key roles in maintaining normal heart rhythm and health of the cardiovascular system. Dehydration causes decreases in blood pressure, forcing the heart to increase its rate during periods of heat exposure if an individual is dehydrated”.

Read Also: Heatwave Hacks: A Complete Survival Plan for Extreme Indian Summer

How To Stay Fit During a Heat Wave?

• Drink water consistently at regular intervals instead of gulping large quantities at once. Electrolyte-rich fluids like coconut water, lemon water with a pinch of salt, or buttermilk are healthy, affordable options to soothe parched throats.

• Add items like curd, rice, cucumber, and bottle gourd to your diet and avoid red meat and fried foods during peak summer days.

• Extreme temperatures put additional stress on the cardiovascular system, especially in people with hypertension, diabetes, or heart conditions. Make sure to take all prescribed medications exactly as advised—don’t skip doses even if you experience heat-induced nausea. If you feel dizzy or experience palpitations or severe fatigue, consult your doctor as soon as possible.

• Air conditioning is helpful, but overexposure can lead to dry skin, headaches, and respiratory discomfort. Once every two or three hours, step away from your desk for a few minutes. Walk or stand, and sip some water.