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Weight loss is usually considered a good thing, unexpected and extreme weight loss can be a sign of something in your body going very wrong. There could be some underlying issues that are causing your body to pull weight and nutrition from your muscles and body fat to keep you going. As you grow old, your limbs grow weaker, and same for your muscles, so you do lose some weight as you age, but losing a lot of it too quickly could be a sign of something much worse, Dementia. A recent study published in JAMA Network Open 2025 Cardiometabolic Trajectories Preceding Dementia in Community-Dwelling Older Individuals, has identified potential early indicators of dementia, including significant weight loss and specific digestive changes, appearing years before noticeable cognitive decline.
The study showed that people who later got dementia had their Body Mass Index, or BMI, go down faster than those who stayed healthy. BMI is a way to see if someone's weight is healthy for their height. This drop in BMI started happening many years before they were told they had dementia, sometimes as early as 11 years ago. Also, these people often started with a lower BMI to begin with. So, even though everyone's weight might change a little as they get older, the people who developed dementia had a much bigger and faster weight loss.
Along with their BMI, the size of their waist also changed. People who ended up with dementia had smaller waist sizes, and this difference was noticeable about 10 years before they were diagnosed. This means that their bodies were changing in ways that showed up long before they or their doctors noticed any problems. So, not only was there weight loss, but also a loss of abdominal fat. This measurement is important because fat around the waist can be related to other health issues.
The study also found changes in their blood. Specifically, the "good" cholesterol, called HDL, went up in people who developed dementia. This increase happened about five years before they were diagnosed. It's tricky because HDL is usually seen as a good thing for your heart. But in this case, it seems like it might be a sign of changes happening in the brain. Scientists are still trying to understand why this happens.
When we see that people with dementia lose weight, it's easy to think that the weight loss is what caused dementia. But experts think it's the other way around. They call this "reverse causation." This means that the brain changes that cause dementia also cause people to lose weight. The brain changes can affect things like appetite, how the body uses food, and how people go about their daily lives. For example, people might forget to eat, have trouble making meals, or move around less.
While the study revealed a lot about different indicators of dementia and bodily changes, there are many limitations to the study. Everyone loses some weight as they get older. So, it's hard to know when weight loss is just a normal part of aging and when it's a sign of dementia. The study found that people with dementia lost weight faster, but it's still tricky to tell the difference in everyday life. Doctors need to look at other things, like memory tests, to figure out if someone's weight loss is a cause for concern.
If someone is losing weight without trying, and they're also having problems with their memory or thinking, it's important to talk to a doctor. It's not just about the weight loss; it's about the whole picture.
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Most women who've had preeclampsia remember it as something that happened during pregnancy. The blood pressure spiked, doctors kept a close watch, the baby arrived, and everything went back to normal.
Case closed, or so it seems. But there's a quieter part of this story that doesn't get told nearly enough - what preeclampsia might mean for a woman's heart years down the line.
It's a condition that can happen after the 20th week of pregnancy, when blood pressure rises sharply and starts putting pressure on organs like the kidneys or liver. During preeclampsia, the lining of blood vessels - the endothelium - becomes inflamed and doesn't relax and dilate the way it normally should.
This is the same vessel dysfunction we see in the early stages of coronary artery disease, just decades ahead of schedule. Doctors usually catch it through routine checks - protein in the urine, sudden swelling, or blood pressure readings that don't sit right.
Once the baby is delivered, blood pressure almost always comes back down. That "return to normal," though, doesn't mean the story is over.
Also read: Vitamin D & Pregnancy: Could Vitamin D Deficiency Increase Risk Of Premature Birth?
Think of preeclampsia as an early stress test that the heart didn't quite pass. It is associated with increased risk of hypertension in future and also increase the risk of heart failure, stroke and cardiovascular diseases. And this isn’t a risk that shows up only in old age, in some cases, death happens within the first 10 years after pregnancy.
The risk of heart failure also increases by four-fold and the risk of coronary heart disease by two folds in patients with preeclampsia. The risk of ischemic heart disease and hypertension is elevated too. The risk increases further if preeclampsia occurred early in pregnancy, during multiple pregnancies, or alongside other factors like obesity or a family history of heart disease.
It highlights the importance of life law monitoring of cardiovascular rest factors in a woman who has history of preeclampsia.
Also read: PMOS Isn't Just About Periods Or Pregnancy: Why Women Need To Think Beyond Fertility
Once the baby is here, attention naturally shifts entirely toward the newborn - and a new mother's own follow-ups tend to fall away quietly, usually right after that standard six-week check. That's the gap, we need to close in postpartum care. Women with a preeclampsia history should regularly monitor their blood pressure, cholesterol and blood sugar, and actually bring these numbers up during the consultation.
None of this means preeclampsia guarantees heart disease down the road. It just means the risk picture has shifted, and that's worth knowing. Staying active, eating well, keeping weight in check, and staying away from smoking helps reduce the risk.
More obstetricians and cardiologists are starting to treat preeclampsia as something to track for life, not just for nine months. That shift in thinking could end up protecting a lot of hearts long after the pregnancy itself is over.
By Dr Waseem Farooqui, Consultant, Interventional Cardiology, Cardiac Care, Medanta Hospitals, Noida
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After a brain bleed, controlling blood pressure is crucial—but is it enough to prevent another stroke? Neurologists explain why consistent BP monitoring, regular medicines, lifestyle changes, and follow-ups matter after discharge. They also share warning signs families should never ignore and when sudden BP rises require urgent medical attention.
Dr Shubha Subramanian - Senior Consultant - Neurology - Kauvery Hospital, Vadapalani, Chennai told Health and Me, "After a brain bleed, controlling BP is extremely important, but this is only for spontaneous intracerebral haemorrhage, not in cases of an AV malformation, an aneurysm-related bleed, or a traumatic bleed, where the aetiology is different." He added, "In case of idiopathic spontaneous intracerebral haemorrhage, probably because of BP fluctuations or high BP, in that case, for secondary prevention, there will be a reduced number of bleeds if the BP is well controlled. Consistent control is very, very important."
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After a brain bleed, patients should regularly monitor blood pressure and pulse, with diabetics also checking blood sugar at home. Periodic blood tests and ECGs may be advised. Families should watch for confusion, seizures, weakness, changes in speech, or facial drooping. Recognising these warning signs early and maintaining consistent BP control can help prevent another bleed.
"Common mistakes include missing medications, not monitoring blood pressure regularly, stopping follow-up visits when they are feeling better, smoking and consuming too much alcohol, and returning too soon to strenuous activity," said Dr. Soniya Tambe, Consultant, Neurology, Fortis Hospital, Bannarghetta Road, Bengaluru. She added, "Patients also may ignore symptoms such as severe headache, weakness, speech difficulty, or vision changes. These signs should never be dismissed."
Recovery after a brain bleed doesn’t stop when a patient leaves the hospital. The steps taken at home are equally important in reducing the risk of another stroke. Along with taking medicines as prescribed and keeping blood pressure under control, patients should focus on making healthy, long-term lifestyle changes rather than following temporary restrictions.
A balanced, low-salt diet can support recovery, while smoking and alcohol should be avoided. Patients should ease back into physical activity gradually and only with their doctor’s advice, especially in the early recovery period. Getting enough sleep, maintaining a healthy weight, and managing stress are also important. Regular follow-ups help monitor blood pressure and other heart-related risk factors.
Dr. Praveen Chander, Senior Consultant Neurology, Gleneagles Chennai, told Health and Me, "Families should also recognise sudden weakness or numbness, difficulty speaking, confusion, loss of balance, severe headache, or sudden vision changes as possible warning signs. These symptoms require immediate medical attention rather than waiting for them to settle."
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Alcohol use among US adults has declined for the first time since the COVID-19 pandemic began, driven largely by Gen Z and millennials, a new study found.
However, alcohol use remains above pre-pandemic levels, according to the findings published in the Annals of Internal Medicine.
"It’s encouraging to see alcohol use decline for the first time since the start of the pandemic,” said Brian P. Lee, a hepatologist and liver transplant specialist with Keck Medicine at the University of Southern California and principal investigator of the study.
“However, use remains above pre-pandemic levels and certain groups continue to have concerning trends," he added.
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Researchers analyzed National Health Interview Survey data from 114,352 US adults between 2018 and 2024.
Heavy drinking was defined as five or more drinks per day or 15 or more drinks per week for men, and four or more drinks per day or eight or more per week for women, in the 12 months before the survey.
From 2022 to 2024, any alcohol use fell by nearly 2%, while heavy drinking declined by more than 8%.
Researchers said this was the first confirmed reduction in alcohol consumption since the pandemic began, following increases in drinking reported in previous studies.
The biggest decline in any alcohol use was among Gen Z adults, whose consumption fell by more than 5%.
Millennials recorded the largest drop in heavy drinking, at 17% between 2022 and 2024.
The study did not examine why younger adults reduced their drinking, though researchers noted that changing social attitudes toward alcohol may be one explanation.
In contrast, alcohol use increased among adults aged 50-64. From 2018 to 2024, any alcohol use in this group rose by nearly 4%, while heavy drinking increased by more than 36%.
According to Lee, the increase is particularly concerning because older adults face higher risks of alcohol-related conditions, including liver disease, certain cancers and cardiovascular disease.
"Heavy drinking among ages 50-64 is up by more than a third since 2018, a concerning trend because this age group faces some of the greatest risks of harm from alcohol, including cirrhosis and alcohol-related cancers,” Lee said.
Men saw a larger decline in any alcohol use than women, 2.4% versus 1.1%. However, heavy alcohol use fell more among women than men, 9% versus 7.7%.
Lee noted that understanding differences in drinking patterns could help develop more effective prevention and treatment strategies.
Read More: Heart Diseases, Mental Disorders And Cancer Among 62 Health Risks Linked To Alcohol Use: Study
Excessive alcohol consumption is one of the leading preventable causes of illness and death in the US, according to the Centers for Disease Control and Prevention.
Alcohol accounts for approximately half of all liver-related deaths, while alcohol-associated cirrhosis has become the leading cause of liver transplants, according to Lee.
The World Health Organization says health risks begin with the first drop of alcohol, meaning no level of consumption is completely safe or risk-free.
Although the decline in alcohol use is a positive development, "we cannot assume alcohol-related harms will decline automatically,” said Lee. “Continued attention to screening, prevention and treatment will be critical, particularly among groups where alcohol use remains elevated.”
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