“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

Millionaire longevity entrepreneur Bryan Johnson has launched a new $2.6 million women's health research project focused on his partner, Kate Tolo's menstrual blood.

Known for his unconventional longevity experiments, Johnson is now aiming to better understand women's reproductive health by preserving and studying Kate's menstrual blood.

“Kate’s period blood is in my -80 °C freezer. Around 10 mL,” he shared in a post on social media platform X.

He added that “menstrual blood is valuable and underutilized,” as it contains “endometrial cells, immune cells and stem cells.”

Why Is Bryan Johnson Studying Menstrual Blood?

Calling both himself and Kate "science experiments," Johnson said the 100-day project aims to:

• Look for diseased tissue
• Measure microplastics
• Measure endocrine disruptors
• Measure PFAS (per- and polyfluoroalkyl substances)

“It’s a non-invasive look into the uterus. This is great because you get the data without surgical biopsy, it can be repeated every single cycle, and it measures the uterine environment directly instead of inferring it from a standard blood draw,” Bryan said.

Also read: Bryan Johnson Plans To Create 'Bryan In A Dish' Living Lab To Test Experimental Autoimmune Treatments

Inside the $2.6 Million 100-Day Project

The project requires Kate to follow an intensive 24/7 routine designed to create what the couple says will be the most detailed dataset ever collected on the female menstrual cycle.

Her minute-by-minute schedule includes more than 100 daily tasks, 50 monitoring devices, and an experimental "techno tampon," generating an estimated 14 million data points under the supervision of a 12-person medical team.

"I am going to be the world's most measured women in this process," Kate shared in in a video posted on Instagram.

The project, backed by the couple's company Immortals, costs an estimated $2.6 million a year.

Kate will collect approximately 14 million data points on her menstrual cycle.

Read More: Bryan Johnson Blames Sugary Cereals, Soda and Stress for His Autoimmune Disease; Shares Treatment Plan

Kate Tolo's Health Conditions

Kate has previously revealed that she has endometriosis, polycystic ovary syndrome (PCOS), and adenomyosis—painful gynecological conditions that she hopes this ambitious research project will help better understand and eventually treat.

“I’m measuring 1,900 biomarkers over the next 100 days to better understand female biology,” she said.

“This will be the most quantified menstrual cycle ever. And this is just to collect baseline measurements. Once we’re done with the 100 days, we’ll start trying interventions. We’ll post all results, including the good, bad and ugly, in addition to sharing all the practical insights,” Bryan added on X.

Earlier, Bryan claimed his team diagnosed Kate's endometriosis “in 42 days… which is 57x faster than average.” The condition affects approximately 10% of women of reproductive age globally and takes an average of 10 years to diagnose.

According to Bryan, his team diagnosed her “without surgery. Via ultrasound, blood test, and MRI.”

Bryan Johnson's Goal

Bryan, who has said he is living with the autoimmune condition autoimmune atrophic gastritis (AIG) and is undergoing treatment, believes advances in AI and biotechnology could help find treatments for both his condition and Kate's endometriosis.

“My sincere goal is to try and heal the sick. With AI and biotech, we no longer have to concede to disease. We don’t need to wait for big, billion-dollar companies to do it for us. I’ll cure my AIG, and we will cure Kate’s endo, and then make the same available to others.”

Amid as many as 45 states in the US battling Cyclospora parasite infections, the UK has now reported a sharp rise in watery diarrhea-causing infections among travelers returning from Mexico.

The UK Health Security Agency (UKHSA) clarified that cyclospora, caused by the parasite Cyclospora cayetanensis, does not naturally occur in the UK and cannot spread from person to person.

The agency has advised travelers to take precautions while abroad, including maintaining good food and water hygiene to reduce their risk of infection.

According to the latest data, 67 cases were reported between April 30 and July 15, among returning travelers in

• England (30),
• Scotland (27),
• Wales (10).

The agency noted that travel information was available for 52 of the 67 cases. Of these, 48 people had traveled to Mexico, with one also reporting travel to the US. One case involved travel only to the US, while another had traveled to Kenya.

Among those who visited Mexico, cases reported staying at various hotels in the Riviera Maya and Cancún regions and consuming a range of foods and drinks as part of all-inclusive holiday packages. Investigations into the source of the infections are ongoing, the UKHSA said.

"We have recently detected a rise in Cyclospora infections among travelers returning from Mexico. These infections are caused by a parasite and can affect the stomach and intestines," said Dr. Philip Veal, Consultant in Travel Health at UKHSA.

"If you develop symptoms after returning from travel, such as watery diarrhoea, loss of appetite, weight loss, stomach cramps or pain, bloating, increased wind, nausea, fatigue or other flu-like symptoms, please seek medical attention and inform your healthcare professional of your travel history," he added.

Cyclospora Outbreak In US: The Mexico Connection

Also read: Michigan Cyclosporiasis Outbreak Nears 10,000 Cases: Is Your Lettuce Safe?

The US is experiencing its largest Cyclospora outbreak, with infections reported across 45 states. The US Food and Drug Administration (FDA) has linked the outbreak to iceberg lettuce grown by Taylor Farms in central Mexico, prompting the company to initiate a recall on July 17.

As per the Centers for Disease Control and Prevention's (CDC) weekly update on July 28, there have been 6,707 laboratory-confirmed cases of the illness, recorded in 45 states, since May 1. In addition, more than 11,500 additional cases, primarily in Michigan and Ohio, have not yet been confirmed by laboratories, the CDC said.

There have been 423 hospitalizations and no deaths, per the agency.

Foods Travelers Should Avoid

Dr. Philip Veal advised travelers to Mexico to avoid foods that may be contaminated with Cyclospora, particularly:

• Fresh, uncooked berries
• Fresh herbs
• Unpeeled fruits
• Raw salad items
• Ice in drinks
• Smoothies and juices that may contain raw fruits or vegetables

Read More: UK, France Brace for Another Heatwave: How Hot Weather Can Affect Medicines

Further, to reduce the risk of infection, the UKHSA also recommended:

• Washing hands regularly with soap and clean water. Use alcohol-based hand sanitizer only when handwashing facilities are unavailable.
• Drinking bottled or boiled water where tap water is unsafe, including for brushing teeth.
• Choosing fruit that can be peeled, such as bananas and oranges.
• Opting for pasteurized dairy products.
• Eating freshly cooked food served hot.
• Following good food and water hygiene practices, even when staying at high-end all-inclusive resorts.

What Is Cyclospora?

Cyclospora is a parasite that infects the stomach and intestines and is typically acquired by consuming contaminated food or water.

Symptoms include:

• Frequent watery diarrhoea
• Abdominal cramps
• Bloating
• Nausea
• Excessive gas (flatulence)
• Low-grade fever
• Loss of appetite
• Weight loss

Most cases are mild and resolve within a few days without treatment. However, the illness can be more severe or prolonged in people with weakened immune systems, who may require antibiotic treatment.

Vibrio vulnificus, a rare "flesh-eating" bacterium, has claimed its first life of 2026 in the US state of Florida, according to state health officials.

Florida health data show that, as of July 30, the state has reported 12 confirmed cases this year, including one death in an elderly person in Palm Beach County. In 2025, Florida recorded 33 Vibrio vulnificus infections and five deaths linked to the bacterium.

What Is Vibrio Vulnificus?

Vibrio vulnificus is a naturally occurring bacterium found in warm saltwater or brackish water, which is a mix of salt and freshwater. It thrives particularly well during the hotter months, which is why infections spike from May through October.

According to the Centers for Disease Control and Prevention (CDC), the bacterium is halophilic, meaning it needs salt to survive.

While rare, the infection can cause necrotizing fasciitis. It is a condition where flesh-eating bacteria could destroy the tissue under the skin and can lead to death in just a few days if left untreated.

How People Get Infected?

The bacterium earned its "flesh-eating" moniker from its ability to cause an infection called vibriosis that damages or "eats away" at skin and tissue.

According to Dr. Norman Beatty, an infectious disease specialist and associate professor at the University of Florida, as reported by WUSF, there are two main ways people typically contract Vibrio vulnificus.

“We can consume it through contaminated shellfish, specifically oysters,” Beatty said. If ingested, the bacteria can cause symptoms like nausea, vomiting, diarrhea, and abdominal cramps.

But the more dangerous and more common route, he explains, is through open wounds. “If someone with a cut or scrape enters brackish or saltwater contaminated with Vibrio vulnificus, the bacteria can enter the body through the skin and cause serious infection,” he warned.

Also read: Rare Tick-Borne Bourbon Virus Case Detected In New York For The First Time

Symptoms To Watch For

Symptoms often appear quickly; sometimes within hours of exposure. Early signs include redness, pain, and swelling around the wound. As the infection progresses, it can cause skin ulcers, blisters, and even tissue death. Systemic symptoms like fever, chills, and low blood pressure may also follow.

“A delay in treatment can lead to serious complications, including amputations or even death,” Dr. Beatty cautioned.

Who’s Most at Risk?

People with weakened immune systems, liver disease, or chronic health conditions are at greater risk of developing severe infections. But Dr. Beatty emphasized that even healthy individuals aren’t immune.

“I’ve seen otherwise healthy people who got a small cut while fishing or kayaking and ended up battling this infection,” he said.

How to Stay Safe?

Read More: Milestone In Kala-Azar Treatment: WHO Updates Treatment Guidelines, Recommends Shorter & Safer Regimens

With summer in full swing and more people spending time in and around water, doctors urge caution. If you have an open wound, avoid wading or swimming in warm seawater or brackish water. If exposure happens accidentally, clean the wound immediately with soap and bottled water. Covering healing wounds with waterproof bandages can also reduce the risk of infection.

If symptoms develop after being in such water or consuming raw seafood, particularly oysters, seek medical attention immediately and inform the doctor of your recent exposure.

A Persistent Health Threat

An average of 100 to 200 cases of vibriosis caused by Vibrio vulnificus are reported in the United States each year, with most of them in Gulf Coast states, according to CDC data. “This is not a bacteria to take lightly. With increased awareness and a bit of caution, we can lower the risk and save lives,” Dr. Beatty said.