“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

A six-year-old boy died after his health worsened during an MRI scan at a private Greater Noida diagnostic centre. His family alleged medical negligence and claimed that he was administered a wrong or heavy dose injection.

As per the boy's father, Prashant Kasana, his son was taken to the centre for some test and was given an injection before the MRI procedure. The family said that during the MRI scan, the child was administered a heavy dose. Due to which his condition worsened and he also lost consciousness.

The family also said that when they asked for information about the child's condition and his medical report, they were not given any satisfactory answers. They also claimed that the doctors gave another dose to the child. The child's condition did not improve and the family had to rush the child to another nearby private hospitals. This is where the doctors declared him dead.

Six-year-old Child Dies of Medical Negligence: What Happened?

After this incident, family members accused the staff of the KB Healthcare Centre, where the child was first taken for an MRI scan. Villagers and workers of the Bharatiya Kisan Union also reached the spot and staged a protest.

The state spokesperson of the Bharatiya Kisan Union, Pawan Khatana, stated that the child was brought to the centre at 10.30am, and was in normal condition. As per the spokesperson, doctors did not disclose the quantity of the dose administered to the child.

As per Khatana, even after half an hour, the child did not gain consciousness and when the doctors checked him again, he was unresponsive and cold. The family took to another private hospital where he was declared dead. Khatana also alleged that there are many such unauthorized screening and imaging centres operating in Greater Noida and demanded a thorough probe.

Six-year-old Child Dies Of Medical Negligence: What Are The Authorities Saying?

Police on reaching the spot received the information, while protesters demanded for a fair investigation and strict action against those responsible. The Station House Officer of Neta 2 police station said the child was a resident of Reelkha in Dankaur. He was brought to a private pathology lab in Sector P3 for an MRI scan. As per the officer, the doctor administered the child with anesthesia for an MRI. After this, the child's health started to deteriorate.

Police has sent the body for post-mortem after completing the necessary legal formalities.

Six-year-old Child Dies of Medical Negligence: How Much Anesthesia Is Safe For A Child During MRI?

As per the National Institutes of Health (NIH), US and a study by the Yeungnam University Journal of Medicine (YUJM), drugs for deep sedation or general anesthesia for pediatric MRI are:

(I) Chloral hydrate: a sedative hyptonic agent with no analgesic properties

The study notes that the recommended dose of chloral hydrate is 50 to 100 mg/kg, or up to a maximum of 2g. The success rate of chloral hydrate sedation for pediatric MRI varies from 78% to 100%.

The United Kingdom (UK) National Institute for Clinical Excellence (NICE) also recommends the use of oral chloral hydrate with a wide margin of safety in children under 15 kg.

The study also notes that children "may be encouraged to take at least clear fluids 2 hours before the procedure for successful sedation without breaking institutional fasting protocols for chloral hydrate sedation".

(II) Pentobarbital: a medium duration barbiturate that provides potent sedation with no analgesic property.

As per the study, this can be administered via an oral or intravenous or IV route. The oral dose is administered between 4 to 8mg per kg and IV dose of 2 to 3 mg per kg.

(III) Midazolam: it is a short-acting water soluble benzodiazepine that has anxiolytic, sedative, amanestiec, and muscle relaxant properties.

It is administered through various routes, but IV is preferred. When administered through IV, it is given at the dose of 0.1mg per kg.

Anesthetic agents include propofol and sevoflurane.

Note: This article is not a substitute for medical consultation or prescription. The information is based on reports and research articles available online for public.

President Donald Trump’s slurred speech at a recent event has sparked renewed concerns for his health. During a White House ceremony, where President Trump was being crowned the “Undisputed Champion of Coal”, his speech briefly slurred and he mispronounced the word, “undisputed.”

A video clip of him saying “And I'm proud to officially name the undithpuut... When did this come out, Mr speaker.” has been making rounds on social media platforms like X. Speculations about President Trump’s dementia and memory loss have been taking over the internet. People are also drawing between the supposed email mentioned in the Epstein files that also mentioned Trump’s supposed memory loss and the continued rumors about his dementia.

Also read: Epstein Files Raise Questions About Trump’s Memory Decline

Is Slurred Speech A Sign of Dementia?

According to Harvard Health, yes, slurred speech can be a sign of dementia, more specifically vascular dementia. While many people associate dementia primarily with memory loss seen in Alzheimer’s, vascular dementia has a different cause and set of symptoms.

Vascular dementia is the second most common form of the condition. It is caused by reduced blood flow to the brain, often due to cholesterol-clogged vessels or a series of "silent" mini-strokes.

Health Conditions That Can Cause Slurred Speech?

Harvard health also explains that slurred speech typically appears in two scenarios

Following a Major Stroke

A significant blockage can cause an abrupt mental shift, often paired with physical symptoms like paralysis or slurred speech.

As a Core Symptom

Because symptoms depend on which specific area of the brain is damaged, some individuals may experience slurred speech and confusion even if their memory remains relatively intact.

Also Read: Donald Trump Alzheimer’s Speculation Rises After Niece Notices Worrying Sign

Trump’s Dementia Speculations

With the influx in conversation surrounding the health of President Donald Trump, it is important to remember that these are not proven claims. On social media, people often point to these "fumbles" as evidence of the president’s cognitive decline or dementia. However, we must understand that the situation is much more complex than that

The White House maintains that the President is in "excellent overall health" and has even released MRI results to back that up. Trump himself often pushes back aggressively against the media for questioning his fitness.

While the public is quick to speculate, experts like neurologists and specialists in aging, say we should be careful. They argue it is impossible, and unprofessional, to diagnose someone just by watching them on TV.

Other Reasons Why Trump’s Health Made News

In 2025, public debate frequently centered on President Trump’s physical health, sparked by visible signs like hand bruising and swollen ankles.

Hand Bruising

Health doubts had been sparked when a bruise on Trump’s hand was highlighted. However, the White House clarified that the bruising on his right hand was a common side effect of daily Aspirin use for heart health, potentially worsened by frequent handshaking.

Swollen Ankles

Similarly, his swollen ankles during the ASEAN summit were attributed to Chronic Venous Insufficiency (CVI), a condition where leg veins struggle to pump blood back to the heart, in an official report from the White House.

MRI Scan

Official MRI results of President Trump also described his cardiovascular and abdominal health as "excellent,". This was shared by Dr. Sean Barbabella, the White House physician, who said that the scans were routine checkups for a 79-year-old and were exceptional for his age.

Cognitive Screening

Trump claimed he "aced" an IQ test, but experts identified it as the MoCA dementia screening. This basic 10-minute exam checks for cognitive impairment rather than measuring a person's general intelligence.

Nipah virus Outbreak In India: After two cases of Nipah virus were confirmed in Kolkata, one of the nurses who has recovered from Nipah virus died of a cardiac arrest. Health and Me previously reported on the male nurse being discharged.

Nipah Virus Outbreak In India: What Happened With The Nurse?

The 25-year-old nurse who recovered from Nipah virus infection died of cardiac arrest on Thursday. As per the official statement given to news agency PTI, "She died of cardiac arrest this afternoon. Though she had recovered from Nipah infection, she was suffering from multiple complications."

The reports show that she also developed a lung infection and contracted a hospital-acquired infection during treatment. The official said, "She was trying to regain consciousness, move her limbs, and speak before her condition suddenly deteriorated. She died at around 4.20pm."

The nurse fell ill in early January after returning home on December 31 for the New Year holidays and was initially admitted to Burdwan Medical College and Hospital before being shifted to the private hospital in Barasat.

Nipah Virus Outbreak In India: What Is Nipah Virus?

As per the World Health Organization (WHO), Nipah virus infection is a zoonotic illness that is transmitted to people from animals, and can also be transmitted through contaminated food or directly from person to person.

In infected people, it causes a range of illnesses from asymptomatic (subclinical) infection to acute respiratory illness and fatal encephalitis. The virus can also cause severe disease in animals such as pigs, resulting in significant economic losses for farmers.

Although Nipah virus has caused only a few known outbreaks in Asia, it infects a wide range of animals and causes severe disease and death in people.

Nipah Virus Outbreak In India: What Are The Common Symptoms?

• Fever
• Headache
• Breathing difficulties
• Cough and sore throat
• Diarrhea
• Vomiting
• Muscle pain and severe weakness

Nipah Virus Outbreak In India: What Are Experts Saying?

Dr Krutika Kupalli, a Texas-based expert who formerly also worked with the World Health Organization (WHO), told The Daily Mail that the possibility of Nipah virus outbreak is 'absolutely' something the Centers for Disease Control and Prevention (CDC) should be 'closely monitoring'.

Read: Experts Reveal Risks Of Nipah Virus Outbreak In The US, CDC On Alert

“Nipah virus is a high-consequence pathogen, and even small, apparently contained outbreaks warrant careful surveillance, information sharing, and preparedness. Outbreaks like this also underscore the importance of strong relationships with global partners, particularly the WHO, [which] plays a central role in coordinating outbreak response and sharing timely, on-the-ground information," she said.

A CDC spokesperson told The Daily Mail that the agency is in 'close contact' with authorities in India. "CDC is monitoring the situation and stands ready to assist as needed."