“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

One of the most debated claims that sunscreen may significantly increase the risk of skin cancer is putting an old study back in focus. We took a closer look at the research and it shows a far more complicated picture than social media noise.

Study On 470,000 Participants

The controversy stems from a 2023 study based on data from more than 470,000 UK Biobank participants.

The research studied how genetic and environmental factors interact to impact the risk of skin cancer. It found that people who used sunscreen frequently had higher observed rates of melanoma, basal cell carcinoma, and cutaneous squamous cell carcinoma.

Compared to people who rarely or never reported using sunscreen, those who always used it had an observed relative risk of about 3.92 for invasive melanoma, 2.40 for basal cell carcinoma, and 2.26 for squamous cell carcinoma.

Can Sunscreen Use Contribute To Risk Of Skin Cancer?

The the crucial part of the study is that it did not establish that sunscreen directly causes skin cancer.

The observational research was primarily designed to investigate gene-environment interactions, not to test whether sunscreen causes skin cancer.

The authors themselves described the sunscreen association as surprising and discussed several possible explanations. One of them is “sunscreen paradox.”

Also read: Scientists Find Rare Contagious Skin Cancer In Fish From US, Canada: Should Humans Worry?

What Is The 'Sunscreen Paradox'?

People who spend more time outdoors, have accumulated more UV exposure, or already have a higher risk of skin cancer may be more likely to use sunscreen in the first place. Sunscreen use can therefore become a marker of higher sun exposure rather than the cause of the cancer.

Lead author Ivan Litvinov told AAP FactCheck that the viral interpretation had misrepresented the findings. “The post misinterpreted the results of our study,” he said.

Litvinov also explained that sunscreen can create a false sense of security when people use too little, fail to reapply it or treat it as permission to stay in the sun longer. This indirectly contributes to the risk of skin cancer. “When sunscreen is used as a ‘permission to tan’, problems arise,” he said.

Should You Stop Using Sunscreen?

Current evidence does not support the conclusion that one must stop using sunscreen to avoid skin cancer.

A randomized trial based on 1,621 adults in Australia found that regular sunscreen use was linked with fewer melanomas over long-term follow-up. Invasive melanoma was substantially lower among those assigned to daily sunscreen use.

More recently, a 2026 review of photoprotection concluded that daily sunscreen use reduces actinic keratoses and cutaneous squamous cell carcinoma in high-risk people, although evidence for basal cell carcinoma and melanoma prevention is more heterogeneous.

Also read: How Vitamin D Helps Protect Your Skin And Lower Cancer Risks Naturally

How Can You Protect Your Skin Without Using Sunscreen?

While sunscreen is important, one must follow some other steps to ensure complete protection. Here are some tips you should remember according to American Academy of Dermatology Association.

Find Your Shade

The sun's rays are most powerful between 10 a.m. and 2 p.m. During these hours, it's best to seek shade. A good rule of thumb: if your shadow is shorter than you are, the sun is very strong, and you should definitely look for some cover.

Dress For Sun Protection

Whenever you can, wear sun-protective clothing. This means choosing things like a lightweight, long-sleeved shirt, long pants, a wide-brimmed hat, and sunglasses with UV protection.

For even better defense, look for clothing labels that have an Ultraviolet Protection Factor (UPF) number, which tells you how much UV radiation the fabric blocks.

Say No To Tanning Beds

Both the sun and tanning beds give off harmful ultraviolet (UV) light, which can cause skin cancer and wrinkles. It's best to avoid tanning beds completely.

If you want to have a tanned look, consider using a self-tanning product instead, but remember to still use sunscreen along with it for actual sun protection.

Be Extra Careful Near Reflective Surfaces

You need to be especially cautious when you're near water, snow, or sand. These surfaces are highly reflective, meaning they bounce back the sun's damaging rays, which can significantly increase your chance of getting a sunburn.

COVID-19 is surging in some parts of California as wastewater surveillance showing a sharp rise in the amount of virus circulating in the surrounding communities.

The latest data comes as California health officials warn that the state’s COVID-19 pattern appears to be shifting, with summer outbreaks becoming more prominent than winter ones.

According to the California Department of Public Health data cited by the San Francisco Chronicle, COVID-19 outbreak expanded in June, rose through July and continued rising in August. Hospital admissions are also increasing, although they remain relatively low compared to previous outbreaks.

WastewaterSCAN data showed that COVID-19 concentrations across monitored Bay Area sites were 136% higher in July than in June. By early August, nearly 54% of monitored sites were classified as having “high” levels, with San Francisco, San Jose, Sunnyvale, San Rafael, Vallejo and Napa among the communities reporting high levels of cases.

“Monitoring wastewater can act as an early warning system for health officials and the public,” said Amanda Bidwell, WastewaterSCAN’s scientific program manager.

Wastewater Surveillance Reveals COVID-19 Resurgence

Wastewater surveillance looks for traces of SARS-CoV-2 in sewage. Because infected people can shed the virus even when they have mild or no symptoms, wastewater can provide an early picture of infections spreading through a community.

The CDC says wastewater trends can detect viruses earlier than clinical testing and can also capture infections that never result in a doctor's visit. An increase in wastewater viral activity may therefore signal a higher risk of infection in the community.

California is currently one of only four U.S. states where COVID-19 wastewater activity is classified as moderate or high by the CDC, according to the Los Angeles Times. The CDC also says COVID-19 is growing or likely growing in 43 states.

Also read: BMJ Public Health Retracts Controversial COVID Vaccine Study Cited In US Senate Hearing

Is A Dangerous New COVID Variant Causing The Surge?

Wastewater monitoring suggests several variants are circulating rather than one strain. In the Bay Area, XFG, also known as “Stratus,” remains prominent, while NB.1.8.1, or “Nimbus,” is also circulating.

Stanford infectious disease expert Dr. Abraar Karan said there is currently no evidence suggesting a dangerous or different virus or a variant that is expected to cause a major increase in hospitalizations or causalties.

Experts say the current wave should not be confused with the severe COVID-19 surges of the pandemic's early years. According to recent data and reports, hospitalizations remain comparatively low compared to previous outbreaks.

However, California health officials are urging people who have not received the 2025-26 COVID-19 vaccine to consider getting it now rather than waiting for the updated vaccine expected later this year.

“Summer is really the bigger peak,” California Public Health Officer Dr. Erica Pan said. “Go ahead and get it now, given the surge.”

The timing could become important as schools reopen and people spend more time in crowded indoor settings. In 2025, California's summer COVID-19 wave peaked later in the season, meaning the current increase may not be over yet.

V, a member of K-pop sensation BTS, has revealed that he has been dealing with hearing loss in one ear for about two and a half years.

V, whose real name is Kim Tae-hyung, opened up about the condition for the first time during a livestream amid the band's highly anticipated world tour.

"If the hearing in my left ear is at 100, it's only about 30 in my right," V said.

The 30-year-old singer said his hearing became worse while he was serving in the military. However, he initially ignored the problem, believing it was "a matter of mental strength," BBC reported.

He said he is now taking medication and visiting the hospital regularly.

V Reveals Risk Of Stress Fracture

V also admitted to pushing through pain during BTS' current tour, revealing that he is dangerously close to developing a stress fracture in his leg.

“My shin is right at the point just before a stress fracture. Even today on stage, my heart was set on running around, but it hurt too much at points and I couldn’t," he was quoted as saying by Channel News Asia.

Doctors have warned him about inflammation and early bone damage.

“It hasn’t reached a stress fracture yet, but there’s a lot of inflammation in my shin, and I think there’s some microdamage to the bone. I’ll be careful with myself so I can finish this tour properly,” he added.

BTS is currently halfway through its massive Arirang world tour, which will stop in Singapore in December and conclude in the Philippines in March 2027.

What Is Hearing Loss?

Hearing loss can happen when any part of the ear is not working in the usual way. This includes:

• The outer ear
• The middle ear
• The inner ear
• The hearing or acoustic nerve
• The auditory system in the brain

Hearing loss is a growing health concern worldwide. According to the WHO, more than 1.5 billion people—nearly 20% of the world's population—live with some degree of hearing loss. Of these, approximately 430 million people have disabling hearing loss requiring rehabilitation.

Hearing loss can have a significant impact on a person's life, affecting education and job prospects.

What Causes Hearing Loss?

Hearing loss can occur at any time during life. Causes can range from genetic factors to conditions such as Down syndrome or Usher syndrome.

Other factors include:

• Maternal infections during pregnancy
• Complications after birth
• Spending five days or more in a neonatal intensive care unit (NICU)
• Severe jaundice requiring a blood transfusion

How To Prevent Hearing Loss

To help prevent hearing loss in adults:

• Limit exposure to loud noises above 85 decibels.
• Wear ear protection, such as foam plugs or earmuffs, around heavy machinery or at concerts.
• Keep personal headphone use at safe volumes.
• Manage chronic health conditions such as high blood pressure.
• Avoid putting objects such as cotton swabs inside the ears.