“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

Police in Guinea-Bissau raided the Bandim Health Project on Monday, October 19, and seized a batch of hepatitis B vaccines intended for a controversial trial involving 14,000 newborns, according to an official statement.

The project’s Danish researchers, Peter Aaby and Christine Stabell Benn, are at the center of the dispute. The study received $1.6 million from the US Centers for Disease Control and Prevention (CDC), matched by the Pershing Square Foundation and the Bluebell Foundation, bringing total funding to $3.2 million. US Health and Human Services Secretary Robert F. Kennedy Jr. has praised the researchers’ work.

The police search took place on Monday, involving “investigative procedures aimed at clarifying the circumstances related to the said batch of vaccines”, according to the social media post, which was translated from Portuguese. The announcement noted that seizing the immunizations did not point to “irregularities in the quality, safety, or effectiveness of the vaccines”, The Guardian reported.

Why Is the Hepatitis B Vaccine Trial Controversial?

The proposed trial would randomly divide 14,000 newborns into two groups: one would receive the hepatitis B vaccine at birth, while the other would receive it six weeks later.

The WHO recommends hepatitis B vaccination within 24 hours of birth to prevent mother-to-child transmission.

Why Is Delaying Vaccination a Concern?

Also read: Hepatitis B Infections Could Rise 83% If US Changes Newborn Vaccine Policy: Study

Hepatitis B is highly endemic in Guinea-Bissau, affecting more than 12% of adults. Infants infected at birth have about a 90% chance of developing chronic infection, which can lead to cirrhosis, liver failure and liver cancer.

Stig Børsen Hansen, a member of the University of Southern Denmark’s ethics committee, resigned after the committee narrowly approved the updated protocol. He warned that the trial would expose some newborns to potentially serious infections by delaying vaccination.

What Is the Study Investigating?

Rather than testing the vaccine’s established efficacy, the study aims to investigate the proposed “non-specific effects” of vaccines — potential health effects beyond protection against targeted infections.

Critics argue that delaying a recommended birth dose to investigate these hypotheses exposes newborns to avoidable risks. Former Guinea-Bissau Health Minister Magda Robalo and other critics have also raised concerns about conducting such research in a vulnerable population.

What Have Authorities Said?

The Bandim Health Project published an approval letter from Guinea-Bissau’s national ethics committee, dated July 14. A Danish research ethics committee also approved the study earlier this month.

However, transitional government Health Minister Quinhin Nantote disputed reports that the trial would proceed, telling The Guardian: “This is not even remotely true.”

WHO spokesperson Tarik Jašarević said a study denying newborns the vaccine would be “unethical” and expose them to “serious and potentially irreversible harm.” The WHO is advising Guinea-Bissau’s Ministry of Health on introducing the vaccine and assessing the study’s potential impact.

Why Is RFK Jr. Backing the Researchers?

Anthropologist Peter Aaby founded the Bandim Health Project in 1978. It is now co-led by his wife, epidemiologist Christine Stabell Benn.

Kennedy has called the pair “the deities of vaccine research” at an anti-vaccine conference and cited their research on the diphtheria-tetanus-pertussis (DTP) vaccine. A subsequent study by the researchers produced different results.

Kennedy also called Aaby a “very famous” researcher on Joe Rogan’s podcast in 2023 and cited his work when he halted US funding to Gavi, the Vaccine Alliance.

Stabell Benn served on the hepatitis B working group of the US Advisory Committee on Immunization Practices (ACIP) and presented evidence before the committee voted to end the universal hepatitis B birth-dose recommendation. A federal judge subsequently stayed the decision.

With digital innovation, expanding healthcare access, and a growing focus on self-reliance driving transformation in India's healthcare sector, the Times Network India Health Summit & Awards 2026 is set to return for its third edition.

The event, to be held on October 28th, will bring together policymakers, healthcare leaders, clinicians, researchers, innovators, and industry stakeholders to discuss the future of India's healthcare ecosystem.

Centered on the theme, “The Blueprint for a Future-Ready Healthcare Ecosystem – Innovation. Access. Self-Reliance,” the summit will explore emerging healthcare innovations, collaborations, and policy approaches, culminating in an awards ceremony recognizing excellence across the sector.

As India is advancing in artificial intelligence (AI), digital health, biotechnology, medical technology (MedTech), and indigenous manufacturing, these areas will also be central to discussions on strengthening the country's healthcare ecosystem.

Summit At A Glance

Anupriya Patel, Union Minister of State for Health and Family Welfare and Minister of State for Chemicals and Fertilizers, is expected to attend as the chief guest.

The second edition of the Times Network India Health Summit & Awards 2026 will feature:

• 30+ speakers
• 400+ delegates
• 12+ knowledge sessions

Six Key Healthcare Discussion Areas

The summit will feature six panel discussions covering key areas of healthcare innovation, access, and policy.

• Advanced Healthcare Infrastructure And Clinical Excellence: Scaling advanced care through AI, Centres of Excellence, and digital innovation.
• Fertility And Reproductive Healthcare: Exploring reproductive technologies, precision medicine, and patient access.
• India's Biopharma Growth: Advancing research, therapeutics, and resilient manufacturing.
• Precision Diagnostics: Leveraging AI, genomics, and personalized care.
• Integrative Healthcare: Strengthening scientific research and AYUSH integration.
• Healthcare Financing: Improving affordability, access, and sustainability through insurance and public-private partnerships.

The summit is being held in association with Onextel Communications Media, co-powered by Novartis and supported by HealthandMe. It will conclude with a felicitation ceremony recognizing excellence across the healthcare sector.

Philadelphia Eagles quarterback Jalen Hurts is expected to miss the remainder of the 2026 NFL season after being diagnosed with deep vein thrombosis (DVT) and blood clots in both lungs.

In a statement on October 19, the team said the 28-year-old was clinically stable with no significant functional limitations. However, he needs blood thinners and cannot participate in contact sports while taking them.

His diagnosis raises questions about how blood clots travel from the legs to the lungs, why they are dangerous and how to reduce the risk.

What Happened To Jalen Hurts?

Hurts was initially diagnosed with a superficial blood clot in his left calf after reporting discomfort following a cleat injury during the October 4 game against the Los Angeles Rams.

Although doctors initially cleared him to play, a follow-up ultrasound in Philadelphia and further testing identified DVT and blood clots in both lungs, known as bilateral pulmonary emboli.

The team said his treatment would involve anticoagulants, or blood thinners. He can resume football activities once he stops taking the medication.

Also read: Hours Of Sitting, Gaming And Binge-Watching OTT? Doctors Warn Of Blood Clot Risk In Young People

What Is Deep Vein Thrombosis?

Deep vein thrombosis occurs when a blood clot forms in a deep vein, usually in the leg. If part of the clot breaks away and travels to the lungs, it can cause a pulmonary embolism (PE), a potentially life-threatening condition.

Prolonged sitting, hospitalization, bed rest, injuries and certain genetic factors can increase the risk of developing blood clots.

How Can A Leg Clot Travel To The Lungs?

A clot can break away from a deep vein in the leg, travel to the right side of the heart and then enter the arteries supplying the lungs. There, it can block blood flow and strain the heart.

“You have a clot in your leg. The problem is it can travel up the veins and go to your heart, and from there, go to your lungs, and block the blood vessels in your lungs,” CBS News chief medical correspondent Dr. Jon LaPook, who is not treating Hurts, told CBS Mornings.

“That's very serious,” he added.

Why Are Athletes At Risk Of Blood Clots?

Read More: World Thrombosis Day: Can An Unexplained Blood Clot Be The First Sign Of Cancer? Experts Explain

Hurts is not the first high-profile athlete to experience blood clots. Tennis star Serena Williams has a history of clots, while NBA Hall of Famer Chris Bosh retired early following blood-clot-related complications.

Fitness does not eliminate the risk. Injuries and prolonged immobility, including during long-haul flights, can slow blood flow and contribute to clot formation.

DJ Corey, director of Northeastern University’s EMT program, said extended periods of sitting during air or road travel can increase the risk because leg muscles help maintain blood circulation.

The US Centers for Disease Control and Prevention (CDC) also warns that limited mobility during long-distance travel can increase the risk of venous thromboembolism (VTE), which includes DVT and pulmonary embolism.

How Can Travellers Reduce Their Risk?

To improve circulation during long journeys, the CDC recommends:

• Moving the legs frequently while seated.
• Walking periodically when it is safe to do so.
• Avoiding prolonged immobility.
• Consulting a doctor about preventive measures if you have additional risk factors.

Compression stockings may help some travellers at increased risk, depending on their medical needs.

What Are The Warning Signs Of Blood Clots?

DVT symptoms can include leg swelling, pain, tenderness, warmth and skin discoloration. Some people may have no obvious symptoms.

Pulmonary embolism warning signs include sudden breathlessness, chest pain, a rapid heartbeat, lightheadedness and coughing up blood.

Sudden breathing difficulties, chest pain or fainting require immediate medical attention, as a pulmonary embolism can be life-threatening.