“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

California mushrooms poisoning has led to four deaths and three people who required liver transplant. This happened after people consumed the death cap mushroom that is proliferating in California following a rainy winter.

The California Department of Public Health has urged people to avoid mushroom foraging altogether as death cap mushrooms could easily be confused with the safe and edible ones.

California Mushroom Poisoning: How Many Cases So Far?

Since November 18, 2025, there have been more than three dozens cases of death cap poisoning. This included three people getting liver transplants, confirmed the health department. Among the cases, four were also reported to be dead. Some of whom sought medical attention suffered from rapidly evolving acute liver injury and liver failure. Other patients were required to be admitted in intensive care units. The patients age ranged from 19 months to 67 years old.

California Mushroom Poisoning: What Is The Death Cap Mushroom?

The death cap mushroom is the most poisonous mushrooms in the world. It is part of a small group of mushrooms that contain amatoxins, which are highly potent compounds and cause 90% of fatal mushroom poisoning globally. They could be found in city parks, forests, and often under oak trees.

Dr Craig Smollin, medical director for the San Francisco Division of the California Poison Control System tells PBS News that in a year, there are between two to five death cap poisonings.

"The main thing this year is just the magnitude, the number of people ingesting this mushroom," Smollin said. "Having almost 40 is very unusual."

With warm temperature along with early rains, a 'super bloom' of death caps in California could be seen.

Experts point out that eating even a small amount could be fatal. The confusing part is that the color is usually not a reliable way to detect toxicity. Furthermore, whether the mushroom is consumed raw, dried or cooked, does not make a difference.

California Mushroom Poisoning: A Case Study

Speaking to San Francisco Chronicle, Laura Marcelino, 36, said that her family in the Northern California town of Salinas gathered mushrooms that looks like the ones she and her husband used to forage in their native Oaxaca. "We thought it was safe".

However, the next day, her husband felt dizzy, but Marcelino was fine. They ate the mushrooms again, heating them up in a soup with tortillas. Her kids do not like mushrooms, so they were safe, as they did not have any. The next day, she and her husband became ill with vomiting, and stayed home form work.

Marcelino spent five days in a hospital, while her husband underwent a liver transplant.

In an email response to The Associated Press, the US Poison Centers said that the cases of mushroom exposure have increased, and not just the death cap. This increase was noted from September through January by 40% from the same period in the previous year. Exposure do not always result in illness or poisoning.

California Mushroom Poisoning: Common Symptoms

• Cramping
• Nausea
• Diarrhea
• Vomiting

Experts point out that early symptoms could go away within a day, but serious to fatal liver damage can still develop within 2 to 3 days

Two people have suffered burn injuries in Mumbai after a cluster of gas-filled balloons exploded and turned into a ball of fire inside a residential building’s lift earlier this week.

The incident occured at Anmol Towers, a residential building opposite a petrol pump in Mumbai's Goregaon West and police have registered a case against the balloon vendor, according to NDTV.

CCTV footage shows a woman entering the lift with a small trolley, followed by a man carrying several balloons packed in a large bag. Moments later, the balloons mysteriously caught fire, leading to the blast inside the elevator.

Despite flames briefly covering the CCTV camera, the woman and two men were seen running out of the elevator seconds later. In the end, the clip shows the elevator doors shutting as flames erupt at the centre of the lift.

It was unclear what type of gas was used to inflate the balloons. However, while many consumers assume decorative balloons are filled with helium, a non-combustible gas, authorities and safety experts suggest that it is highly possible that hydrogen was used instead.

Mumbai police have urged the public to exercise caution and warned balloon sellers against using flammable gases, particularly in residential buildings and enclosed areas.

Why Is Hydrogen Dangerous?

Hydrogen has a very wide range of flammability in air (4-75 percent by volume) and requires very low energy to ignite. It often causes explosions rather than just fires, especially in confined spaces.

In high concentrations in enclosed areas, hydrogen acts as a simple asphyxiant by displacing oxygen, which can lead to dizziness, unconsciousness, or death. Additionally, hydrogen fires burn with a nearly invisible, pale blue flame, making them almost impossible to detect with the naked eye during daylight.

Moreover, hydrogen gas also burns faster than most conventional fuels, increasing the risk of deflagration (subsonic) or detonation (supersonic).

On the other hand, as a noble gas, helium has a completely filled outer shell of electrons, meaning it does not react with other elements or catch fire in the presence of oxygen and heat.

Along with this, unlike hydrogen, which is also lighter than air but highly explosive, helium will not ignite even if exposed directly to a flame or spark and it can can act as a buffer and actually suppress flames by displacing oxygen in the immediate area.

What To Do If You Suffer From Burns?

For minor burns, immediately run cool (not cold) water over the area for 10–20 minutes, remove jewelery or tight clothing near the injured area and cover with a sterile bandage. A minor burn might need emergency care if it affects the eyes, mouth, hands or genitals.

However, for serious and large burns, protect the burned person from further harm and ensure that they are breathing. Loosely cover the area with gauze or a clean cloth and raise the burned area above heart level, if possible.

As you call emergency services, watch for symptoms of shock which include cool, clammy skin, weak pulse and shallow breathing.

Seek immediate care for burns, which:

• May be deep, involving all layers of the skin.
• May cause the skin to be dry and leathery.
• May appear charred or have patches of white, brown or black.
• Are larger than 3 inches (about 8 centimeters) in diameter.
• Cover the hands, feet, face, groin, buttocks or a major joint, or encircle an arm or a leg.
• Are accompanied by smoke inhalation.
• Begin swelling very quickly.

Globally, about 10 million people experience burns and about 180,000 die from them each year.

A woman with no travel history has died from Nipah virus in Bangladesh, the World Health Organization has confirmed.

The patient, aged between 40 and 50, developed a fever and headache-like symptoms consistent with the virus, followed by hypersalivation, disorientation and convulsion on 21 January.

The case was reported in the northern Naogaon district, Sharmin Sultana, senior scientific officer at the Institute of Epidemiology, Disease Control and Research, later said.

She died on January 28 and was confirmed to be infected with the virus the day after. Although she had no travel history, she regularly consumed raw date palm sap, reports suggest.

The WHO said all 35 people who had contact with the now-deceased patient were being monitored and have tested negative for the virus. No new cases had been detected to date.

Since its emergence in 2001, Bangldesh has reported cases of Nipah virus in humans every year. In 2025, four laboratory-confirmed fatal cases were reported in the country.

What's Happening In India?

The Nipah virus outbreak began in West Bengal, India in January with two hospital nurses at AIIMS, Kolkata, testing positive for the infection and being quarantined, prompting widespread testing. Soon after, five cases, including a doctor and a staff member, were confirmed and over 100 people were quarantined.

However, one of the nurses, a 25-year-old unidentified man has now made a recovery and revealed his experience with the virus, claiming that despite irritation in the throat and uncertainty about what lay ahead, he had faith in his doctors and fellow nurses.

In an interview with the Metro, he said: “After I was taken off ventilation and regained consciousness, I came to know that I have Nipah. I still had the tube in my mouth, and there was irritation. Despite the irritation and my fear, I had faith in the doctors and nurses.

“I have suffered and I know the symptoms. I will tell people when they should get checked for the Nipah virus. I want to raise awareness about the virus and its symptoms.

“I am not sure how I came in contact with the deadly virus. Maybe it was while treating a patient. But I will continue to work as a nurse. I am waiting to rejoin the hospital,” he added.

The unidentified healthcare professional remains very weak physically and is undergoing physiotherapy to regain his strength. “I was bedridden for over a month. I am still very weak and have an unstable gait. So, I am undergoing physiotherapy,” he said.

The other nurse, a woman, remains in a coma but has been taken off ventilation support, a hospital official confirmed this week.

Nipah Virus: What Is It And What Are Its Symptoms?

According to WHO, Nipah virus is a zoonotic illness which means it is mostly transmitted from animals to humans through bats. However, it can also spread through fruits that have been contaminated by the saliva, urine or droppings of infected bats. Human-to-human transmission can also occur through close contact with an infected person or their bodily fluids.

The illness has a 75 percent fatality rate, and there are no vaccines to protect the public.

The virus was first identified in 1998 during an outbreak among pig farmers in Malaysia and soon made its way to India and Bangladesh in 2001, with cases often involving family members or caregivers tending to the infected patient.

READ MORE: _{Nipah vs Bird Flu in India: Which Virus Poses A Greater Threat To Humans?}

Although the Nipah virus has caused only a few known outbreaks in Asia, it infects a wide range of animals and causes severe disease and death in people. Some of its common symptoms include:

• Fever
• Headache
• Breathing difficulties
• Cough and sore throat
• Diarrhea
• Vomiting
• Muscle pain and severe weakness

Samples collected from the patient’s home and workplaces, including pets and partially eaten fruits dropped by bats, all tested negative for the virus, and the exact source of the infection could not be identified.