“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

Cancer Postcode Lottery will soon be put to an end by the UK Government. Reports say that it will enable the rural population access to cancer specialists and treatments. Before getting into how it will help the rural population and people living in coastal areas to find it easier to see a cancer doctor, let us first understand what postcode lottery means.

What Is Cancer Postcode Lottery?

The term cancer postcode lottery refers to a situation where a cancer patient’s access to the latest and most effective treatments depends on where they live or which hospital they are treated at, rather than purely on medical need.

Based on the information you shared, senior cancer doctors in England are warning that this is happening because of bureaucratic hurdles within the NHS. Even though cancer care is supposed to be equitable across the country, in practice, not all hospitals can easily offer the same treatments.

How Does This Postcode Lotter Work?

Doctors say that some cutting-edge cancer treatments such as advanced radiotherapy techniques and newer immunotherapy drugs require separate funding approvals. Individual cancer centers often have to apply to NHS England for permission and money to use these treatments.

Larger, better-funded hospitals with more administrative resources are often able to navigate this complex system more easily. Smaller or less well-resourced units may struggle, meaning patients treated there may not get access to the same options.

For instance, Stereotactic Ablative Body Radiotherapy (SABR). SABR is a highly precise form of radiotherapy that delivers strong radiation doses directly to small tumors in areas such as the lungs, liver, brain and lymph nodes. Although SABR is a well-established treatment and can be life-saving for certain patients, the Royal College of Radiologists (RCR) says some cancer units still have to apply for special funding to use it. This leads to situations where a patient in one area can receive SABR, while another patient with the same cancer elsewhere cannot.

What Is The Government Planning To Do With Postcode Lottery?

As per the official website of UK Government, this will allow people "living in rural and coastal communities will find it easier to see a cancer specialist as part of plans to tackle the current postcode lottery."

The website notes that most deprived parts of the country have fewer cancer consultants, which leaves patients waiting longer for essential care. These same areas also face highest economic inactivity, with long waits for diagnosis and treatment keeping people out of work and holding back local economies. This is why the government is now introducing "new training places targeted at trusts with biggest workforce gaps, prioritising rural and coastal areas".

Working with the Royal Colleges, the government will encourage more doctors to train in clinical and medical oncology to increase the number of cancer specialists in underserved areas.

These steps will be outlined in the upcoming National Cancer Plan, which aims to speed up diagnosis and treatment, reduce inequalities, and support the goal of making England a global leader in cancer survival, while building a future-ready NHS.

A treatment already popular in the US for skin care, pain relief, and faster healing may soon be known for something far more serious. A new study suggests red light therapy could help protect football players’ brains from chronic inflammation caused by repeated hits to the head.

Experts say the findings are early but promising, especially in the ongoing search for ways to reduce long term brain damage in contact sports.

What Is CTE?

Chronic traumatic encephalopathy, or CTE, is a degenerative brain disease linked to repeated head injuries. It is commonly found in former football players, boxers, and military personnel exposed to blast injuries. Over time, the condition can cause memory loss, confusion, mood changes, aggression, and eventually problems with movement, speech, swallowing, and breathing. There is currently no cure, and doctors still do not know how to slow its progression.

Why inflammation matters in CTE

For now, the only proven way to lower CTE risk is to reduce repeated brain trauma through better helmets, rule changes, and fewer hits to the head. But with more than 100 former NFL players diagnosed with CTE after death and many more suspected cases, experts agree that prevention tools alone are not enough.

Researchers believe chronic inflammation in the brain plays a major role in how CTE develops and worsens over time. If that inflammation can be reduced early, it could potentially limit long term damage.

Red light therapy, also known as photobiomodulation, has already been shown to reduce inflammation in other parts of the body. It works by stimulating energy production inside cells and improving blood flow, which helps tissues repair and recover.

Inside the football study

To see whether the therapy could help the brain, researchers at the University of Utah Health studied 26 collegiate football players during a full season. Half received active red light therapy using a light emitting headset and a small device placed inside the nose. The other half used an identical looking device that did not emit light.

Players completed three 20 minute sessions each week over 16 weeks. Brain scans were taken before and after the season.

Read: 21-year-old Billy Vigar Of Chichester City Dies Of Sustaining Brain Injury

The results were striking. MRI scans showed that players in the placebo group experienced a significant increase in brain inflammation by the end of the season. In contrast, those using red light therapy showed little to no increase, with protection seen across most brain regions.

Why experts are paying attention

Specialists who reviewed the findings say the results align with what scientists already understand about inflammation and brain injury. Reducing the inflammatory response after repeated impacts could help limit the damage that builds up over time.

Another advantage is that the therapy is non invasive and does not involve medication. Most users report no major side effects, which makes it especially appealing for athletes.

That said, experts caution against buying over the counter red light devices. The therapy requires very specific wavelengths that can penetrate skin and tissue effectively. Many consumer products do not meet those standards.

Researchers stress that more studies are needed to confirm long term safety and effectiveness. A large Department of Defense funded trial is already planned, involving 300 people with persistent concussion or traumatic brain injury symptoms, including veterans and first responders.

If future research continues to show benefits without harm, red light therapy could one day become part of how teams protect athletes’ brains, not just in football, but across many sports.

Nicole "Snooki" Polizzi opened up about a cancer scare. Now, 38, the Jersey Shore star, posted on her TikTok an emotional video, where she explained that she has been dealing with abnormal pap smear results. She said that it has been about four year since the precancerous cells were found. Because of that she had to undergo an "uncomfortable" colposcopy and biopsy.

She said that when the results came back, the doctor informed her that her cervix is "Not looking great". The doctor had found cancerous cells on the top of her cervix. She said that she would soon need a cone biopsy under anesthesia for further testing. "I am terrified. It is scary, but we have to get it done because cervical cancer is nothing to joke about."

She said, "But whatever to keep me healthy and safe to be here for my kids that I have now," referring to her three children with her husband Jionni LaValle.

In her TikTok video, she said that she is scared and freaking out. She also said that she hopes to find community on social media with other women who have been through the same.

She also agreed to delaying her routine examination because of fear. "I waited on my appointments because I knew I might not get great results but also because I didn't want to feel the pain. I didn't want to deal with the stress of having to deal with all of this," she said.

Talking about her TikTok video, she said, “Just making this video to spread awareness to make sure you get your pap smears. And if your doctor calls you to do it again, do it, Make sure you are fine and prevent all the bad things that could happen, like cervical cancer." She said she was nervous but also shared that she received a lot of support from her friends and family. "Being a woman is not easy and is definitely a scary thing. I know I am going to be fine. It is just scary."

Read: Oncologist Reveals 5 Subtle Cervical Cancer Signs That You May Miss

What Is Cervical Cancer?

Cervical cancer develops in a women's cervix (uterus opening) due to abnormal cell growth, primarily caused by persistent HPV infection, a common infection that's passed through sexual contact.

When exposed to HPV, the body's immune system typically prevents the virus from causing damage however, in a small percentage of people, the virus can survive for years and pave the way for some cervical cells to become cancerous.

Treatment involves surgery, radiation, and chemotherapy, with early detection significantly improving outcomes, though it remains a major cancer in low-income countries. Cervical cancer can also be prevented through vaccination and regular screening (Pap/HPV tests).

Dr Ninad Katdare told News18: "In its early stages, it is often more of a whisper than a shout. As a cancer surgeon who has treated hundreds of women with gynaecological cancers, I can say with confidence that recognizing these subtle cues can lead to earlier diagnosis and significantly better outcomes."