Matthew Perry Investigation: Can Ketamine Kill Someone?

Updated Aug 17, 2024 | 12:00 PM IST

SummaryNew evidence has come up in the investigation of Matthew Perry, 'Friends' Chandler Bing's death on October 28. This evidence points to an overdose of ketamine. What is ketamine and how does it affect you? Read now.
Matthew Perry Investigation Can Ketamine Kill Someone

Credits: IMDb

“I'm not great at the advice. Can I interest you in a sarcastic comment?”

Friends Actor Matthew Perry

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

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US Man Says ChatGPT's Medical Advice Nearly Killed Him: How Safe Is AI for Health Questions?

Updated Jul 25, 2026 | 02:00 AM IST

SummaryOpenAI launched ChatGPT Health feature in the US in January this year. At the time, OpenAI said more than 230 million people ask ChatGPT questions about their health and wellbeing every week.
US Man Says ChatGPT's Medical Advice Nearly Killed Him: How Safe Is AI for Health Questions?

Credit: iStock

A Florida man has filed a lawsuit against OpenAI and its CEO Sam Altman, alleging that medical advice provided by ChatGPT nearly cost him his life after the chatbot repeatedly discouraged him from seeking medical care.

Scott Winters, a former pastor, filed the lawsuit in San Francisco County Superior Court, claiming ChatGPT repeatedly advised him against seeking medical help as he experienced symptoms leading up to a near-fatal pulmonary embolism—a sudden and dangerous blockage in an artery in the lungs.

"ChatGPT-4o frequently opined on and evaluated Scott's physical condition, conveying the authority and confidence of a medical professional rendering a clinical assessment and treatment recommendation, despite not having the qualifications to do so," the lawsuit states.

Winters' lawyers further allege that the platform "repeatedly and insistently misdiagnosed" him while drawing on previous discussions about religion to reassure him that he would recover.

What Does The Lawsuit Allege?

Also read: AI Cannot Replace Doctors, It Can Only Complement, Says Dr Santosh Sivaranjani

According to the lawsuit, Winters became a regular ChatGPT user and gradually came to rely on the chatbot for medical advice, resisting repeated efforts by family members and friends to persuade him to visit a hospital.

Weeks before becoming critically ill, he consulted ChatGPT about recurring dizzy spells and "bouts of blood pressure instability."

The lawsuit claims that in one response, ChatGPT advised Winters to remain in the recliner chair to which he had become "mainly confined to" because of his worsening health.

Court documents state that Winters later suffered a "massive pulmonary embolism due to multiple blood clots in both of his lungs that brought him to the brink of death, one that his doctors stated was likely brought on because of his immobility."

Winters is seeking financial damages and is asking the court to require OpenAI to implement "reasonable safeguards that protect other users from harm."

ChatGPT Not Intended For Medical Care

Read More: Women Turning to AI for Health Detection: Helpful Tool or Risky Trend?

Earlier this year, OpenAI launched a new ChatGPT Health feature in the US that can analyze users' medical records to provide more personalised responses, although campaigners have raised privacy concerns.

At the time, OpenAI said more than 230 million people ask ChatGPT questions about their health and wellbeing every week. In a blog post, the company said ChatGPT Health offers "enhanced privacy to protect sensitive data."

"ChatGPT is not a doctor and should never be used as a substitute for medical care, diagnosis or treatment," OpenAI spokesperson Drew Pusateri told CBS News, reacting to allegations.

He added: "AI can make that experience better by helping them find clearer answers, organize their questions and prepare for conversations with medical professionals."

ChatGPT's terms of use state that users should not treat the chatbot as a "sole source of truth," particularly for decisions that could "have a legal or material impact on that person, such as making credit, educational, employment, housing, insurance, legal, medical, or other important decisions about them."

Other Health-Related Lawsuits

This is not the first lawsuit OpenAI has faced over users' health and safety.

In May, a Texas couple whose son died from an overdose after seeking information about drugs from ChatGPT sued OpenAI, alleging he would still be alive if the company had not "bypassed safety guards."

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Sri Lanka's Decade-High Dengue Toll Crosses 76,000 Cases, 56 Deaths

Updated Jul 24, 2026 | 10:45 PM IST

SummaryAbout 75% of cases in Sri Lanka are linked to the more virulent DENV-2 strain, which is spreading rapidly. According to the WHO, global dengue cases have risen from around 500,000 in 2000 to 14.4 million in 2024.
Sri Lanka's Decade-High Dengue Toll Crosses 76,000 Cases, 56 Deaths

Credit: AI generated

Sri Lanka is facing its worst dengue outbreak in over a decade, with 76,044 cases and 56 deaths reported so far in 2026, according to the National Dengue Control Unit (NDCU).

With the onset of the monsoon season, infections have surged sharply. While 8,590 cases were reported in May, the number more than doubled to 21,537 in June. In the first 19 days of July alone, 20,666 cases were recorded, including 2,895 new infections on July 21, the NDCU said.

The country has reported 56 dengue-related deaths this year, with a case fatality rate of 0.07%. According to the World Health Organization (WHO), global dengue cases have risen from around 500,000 in 2000 to 14.4 million in 2024.

Western Province Worst Hit

Sri Lanka's Western Province remains the hardest-hit region, accounting for more than half of all infections nationwide. Health officials have also identified 162 high-risk areas for dengue transmission, Asia News reported.

According to the NDCU, the Ministry of Health is currently conducting surveillance programmes across 63 high-risk divisions. The country is also deploying military drones to identify stagnant water on rooftops and other mosquito breeding sites.

Public Health System Under Pressure

According to Reuters, Sri Lanka's public health services and hospitals are battling the country's worst dengue outbreak in nearly a decade, with the armed forces assisting efforts to contain the spread.

The response includes air force drones tracking rooftop pools of stagnant water after monsoon rains, while military and police personnel are helping inspect homes, construction sites and schools to eliminate mosquito breeding grounds.

Public health workers were "stretched to their limit," said Kapila Kannangara, Acting Director General of the National Dengue Control Unit.

"The number of patients is high, and the severity of the cases is high," he said, adding that about 75% of cases are linked to the more virulent DENV-2 strain, which is spreading rapidly.

Health officials expect infections to decline as monsoon rains weaken in August but warn that cases could rise again from November with the arrival of the island's second annual monsoon season.

What Is Dengue?

Dengue is a viral infection transmitted primarily by Aedes mosquitoes and is common in tropical and subtropical regions worldwide.

Most infections cause high fever and flu-like illness. However, some cases can progress to severe dengue (dengue hemorrhagic fever), which may lead to severe bleeding, shock and death.

Dengue is the most widespread viral disease transmitted by Aedes mosquitoes. More than 3.9 billion people across over 132 countries are at risk, with an estimated 96 million symptomatic cases and around 40,000 deaths reported each year globally.

Symptoms of Dengue Fever

Symptoms usually appear 4–10 days after the bite of an infected mosquito and may include:

  • High fever
  • Severe headache
  • Pain behind the eyes
  • Joint and muscle pain
  • Nausea and vomiting
  • Fatigue
  • Skin rash appearing a few days after fever begins

In severe cases, dengue can cause excessive bleeding, a sudden drop in blood pressure and organ complications.

How to Prevent Dengue

Preventing dengue focuses on avoiding mosquito bites and eliminating breeding sites. Measures include:

  • Using insect repellents containing DEET
  • Wearing long-sleeved clothing, especially during dawn and dusk
  • Installing screens on windows and doors
  • Sleeping under mosquito nets in endemic areas
  • Removing stagnant water from flower pots, gutters and containers
  • Using mosquito traps or insecticide-treated materials in mosquito-prone areas

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US, UK Issue Travel Advisories Over Chikungunya Yellow Fever Risks

Updated Jul 24, 2026 | 10:37 PM IST

SummaryChikungunya and Yellow Fever are both mosquito-borne viral diseases transmitted primarily by Aedes aegypti.
US, UK Issue Travel Advisories Over Chikungunya, Yellow Fever Risks

Credit: AI generated

The US Centers for Disease Control and Prevention (CDC) and the UK Health Security Agency (UKHSA) have issued travel health advisories warning travelers about the growing risks of mosquito-borne diseases, including chikungunya and yellow fever.

The CDC has issued a Level 2 Travel Health Notice for Costa Rica following a chikungunya outbreak, while UK health authorities have alerted travelers about rising imported chikungunya cases and yellow fever activity across multiple countries.

CDC Issues Level 2 Travel Health Notice

The CDC warned American travelers to "practice enhanced precautions" after Costa Rica reported a chikungunya outbreak.

On July 1, Costa Rica's Ministry of Health declared an active outbreak in the oceanside community of Playa Langosta in the western province of Guanacaste..

An epidemiological survey identified 45 suspected cases, of which four were laboratory confirmed, while 17 others were considered likely linked to the outbreak.

According to the US Embassy in Costa Rica, the cases include both Costa Rican nationals and foreign visitors. The embassy said local transmission means the virus is now circulating among the local mosquito population rather than being limited to infected travelers.

Costa Rica has reported 16 total cases this year, with the previous reported case dating back to 2017.

UKHSA Warns Over Rising Chikungunya Cases

The UK Health Security Agency issued a warning for holidaymakers travelling to affected regions as imported chikungunya cases continue to rise.

"Are you, or someone you know, heading off on a tropical trip? It's worth being aware of chikungunya, a mosquito-borne virus that can cause severe joint pain. Check out our blog post to learn how to stay protected," the UKHSA said in a post on X.

UKHSA reported 112 confirmed and probable chikungunya cases among travelers returning to England, Wales and Northern Ireland in 2024—almost one and a half times the number reported in 2023.

"Travel to India accounted for the majority of these cases, followed by travel to Pakistan and Brazil – all popular destinations for people travelling from the UK," the agency added.

Yellow Fever Alert Issued for Multiple Countries

The UK government-backed Travel Health Pro has also warned travelers about increasing yellow fever activity.

Since the beginning of 2026, 95 confirmed yellow fever cases have been reported globally.

Confirmed cases have been reported in:

  • Bolivia
  • Brazil
  • Colombia
  • Ecuador
  • Peru
  • Venezuela
  • Burkina Faso
  • Central African Republic
  • Cameroon
The advisory noted that 2025 recorded a 5.6-fold increase in yellow fever cases compared with 2024.

What Is Chikungunya?

Chikungunya is a mosquito-borne viral disease transmitted primarily by Aedes aegypti and Aedes albopictus mosquitoes, the same mosquitoes that spread dengue fever.

Symptoms usually appear three to seven days after an infected mosquito bite and include:

  • Sudden fever
  • Severe joint pain
  • Headache
  • Nausea
  • Fatigue
  • Rash (in about half of cases)

Unlike dengue, chikungunya can leave lingering effects, with joint pain and fatigue lasting for weeks, months or even years.

People at higher risk of severe illness include:

  • Newborns
  • Older adults
  • People with hypertension
  • People with diabetes
  • People with heart disease

The mosquitoes responsible for spreading chikungunya commonly breed in stagnant water found in overhead tanks, coolers and unused containers.

What Is Yellow Fever?

Yellow fever is a viral disease transmitted through the bite of infected mosquitoes. The infection can be severe and may become fatal in some cases if not managed appropriately. Vaccination is recommended before travelling to certain affected regions.

Initial Symptoms

  • Fever
  • Chills
  • Severe headache
  • Back pain
  • General body aches
  • Nausea
  • Vomiting
  • Fatigue
  • Weakness

Severe Symptoms

  • High fever
  • Yellowing of the skin or eyes (jaundice)
  • Bleeding
  • Shock
  • Organ failure

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