“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

In 2018, Google released around three million specially bred male mosquitoes in one trial town to see if disease-causing pests could be controlled. As a result, the local mosquito population fell by approximately 95%.

Google’s parent company, Alphabet, is now also seeking approval for running similar trials in the United States, where mosquito-borne diseases like dengue, Zika and West Nile virus pose continuing public health challenges. Their aim is to reduce mosquito population without relying solely on chemical insecticides.

How Does Releasing Mosquitoes Help Control Them?

Also read: Bangladesh Dengue Outbreak: 90,000 Hospitalized, 281 Dead

The project, known as Debug, focuses on Aedes aegypti, a mosquito species that can transmit dengue, Zika, chikungunya and yellow fever. The method uses male mosquitoes carrying a naturally occurring bacterium called Wolbachia.

When these males mate with wild females that do not carry a compatible strain, the resulting embryos fail to develop. Over time, this reproductive incompatibility can suppress the local mosquito population.

Male mosquitoes do not bite humans or transmit mosquito-borne diseases. Researchers therefore release large numbers of these males to increase the likelihood that wild females will mate with them rather than produce viable offspring.

The Australian field surveys began in 2015, with the mosquito release taking place in 2018. Around three million male mosquitoes were released over 20 weeks across three treatment towns in Queensland. Researchers compared mosquito populations in these locations with those in towns where no mosquitoes were released.

The results, published in 2021, showed that mosquito numbers began declining within four weeks. In one town, monitoring found only a handful of Aedes aegypti mosquitoes 12 months later, representing approximately 95% population suppression.

US Is Considering The Same Approach

Also read: Florida Reports First Dengue Death In Nearly A Century As Cases Surge To 152

Alphabet’s Debug programme has applied to release up to 32 million male mosquitoes in California and Florida, according to a July 2026 report in The Guardian.

A separate US Environmental Protection Agency filing describes proposed experimental releases of up to 16 million mosquitoes annually in New Jersey, California and Florida.

The EPA’s April 2026 notice invited public reactions on the application. The proposed trials are intended to assess whether the released males can mate with wild mosquitoes and suppress their populations.

Additionally, an executive order signed on September 29, 2026, directed federal agencies to develop non-chemical and technology-enabled methods to control invasive mosquitoes and ticks.

Could This Help Reduce Disease Transmission?

Reducing the population of a disease-carrying mosquito species could help lower the risk of transmission. However, fewer mosquitoes do not automatically translate into an equivalent reduction in human infections. The outcome also depends on local mosquito ecology, movement between areas, the diseases circulating, and how consistently the activity is implemented.

The trial results in Australia are promising, but success is not guaranteed. Mosquito behaviour, environmental conditions, population movement and the ability to release enough numbers of males can affect outcomes. Researchers must also ensure that only males are released, since female mosquitoes bite and can transmit disease. The Australian project used specialised technology to separate male and female mosquitoes.

The United States Secretary of Health and Human Services Robert F. Kennedy Jr. recently announcing new measures to expand investigation into health problems and other side effects reported after vaccination.

The initiative includes a new National Institutes of Health (NIH) clinic, payments to doctors for reporting suspected injuries related to vaccines, and changes to the systems used to collect safety data.

Announced on October 8, 2026, the initiative aims to understand possible complications related to vaccines. However, it has also raised questions about whether increased reporting could distort public concern about vaccine safety without sufficient evidence of causation.

“We must listen to patients and families who report vaccine injuries—not dismiss or gaslight them,” Kennedy said in a statement from the Department of Health and Human Services (HHS). “President Trump and I are building a health system that takes them seriously, follows the evidence, and uses what we learn to make vaccines safer. This is how we earn back trust in our public health institutions.”

What Changes Were Proposed By US Health Secretary?

The HHS initiative includes four major measures:

• A new NIH clinic: Opened on October 5, the clinic will study and provide care for people experiencing health problems after vaccination.
• Payments for reporting: The Centers for Medicare and Medicaid Services has proposed reimbursing doctors for reporting suspected vaccine-related injuries to the Vaccine Adverse Event Reporting System (VAERS).
• Electronic health records: The government intends to access electronic health records to track adverse events after vaccination.
• Modernising VAERS: The system will be updated to simplify reporting and improve the tools available to researchers and healthcare professionals. VAERS, jointly managed by the US Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA), already accepts reports from patients, family members, healthcare providers and vaccine manufacturers.

Also read: Nearly 4,000 Measles Cases In US: CDC Director Says MMR Vaccine Is ‘Absolutely Safe’

What Are The Benefits Of Vaccine-Injury Reporting?

Vaccines can occasionally cause adverse side effects. Most reported side effects are mild, but in rare cases, serious events may occur. Identifying these reactions is key for improving vaccine safety.

Expanding reporting could help researchers detect unusual risk factors and identify adverse events. Trials involving relatively small numbers of participants may not always detect very rare complications that can emerge only after a vaccine is administered to millions of people.

More complete electronic health records could also help clinicians identify patterns across different settings, while a dedicated NIH clinic could provide care to patients whose symptoms require further investigation.

Also read: Plague Treatable, CDC Monitoring US Arrivals From Russia After Worker’s Death, Says Director Erica Schwartz

What Are The Risks?

More reports do not automatically mean more vaccine injuries. VAERS accepts reports of health problems occurring after vaccination, even when the person reporting them is unsure whether the vaccine caused the problem.

The CDC explicitly states that a VAERS report does not establish causation. Reports may be incomplete, contain errors or describe illnesses unrelated to vaccination. Establishing a causal link requires further investigation, including clinical assessment and analysis of other possible explanations.

The CDC also warns that media attention and increased public awareness can lead to more reports, complicating efforts to identify genuine safety signals. If raw reporting numbers are presented as proof that vaccines are dangerous, they can create misleading impressions and contribute to mistrust in vaccine.

The proposal to reimburse doctors for reporting suspected injuries also raises questions about how these incentives will be designed, monitored and interpreted. More reports may improve surveillance, but the value of the system will depend on the quality of the information.

Since July 2025, at least 52 maternity units across the United States have been shut down. Eight more closures were announced recently, raising concerns that upcoming federal Medicaid cuts could further restrict access to pregnancy and neonatal care, especially in rural communities and regions with limited healthcare resources.

The closures come as hospitals prepare for changes under the HR1 bill, which will reduce federal Medicaid funding and introduce stricter eligibility rules and work requirements. Although the legislation's impact is expected to be felt in 2027, some hospitals have already cited the anticipated changes as a reason for ending maternity services.

US Maternity Units Are Closing

Also read: High BP in Pregnancy Linked to 42,000 Maternal Deaths, 500,000+ Stillbirths, Newborn Deaths: WHO

Maternity wards are expensive to operate because they require round-the-clock staff, special equipment and teams trained for emergencies. Low reimbursement rates, staffing shortages, and declining birth rates have already placed financial pressure on hospitals. Reduced Medicaid funding could make it harder for some hospitals to keep these services.

Erin Jones, senior director of legislative and strategic counsel at the nonprofit March of Dimes, warned that the changes could worsen existing healthcare problems.

“We’re deeply concerned that these changes already have and will continue to worsen an already serious maternity care crisis,” she said. “Reduced funding and restrictions on how states finance Medicaid will put additional pressure on state budgets and hospitals, increasing the risk that communities lose essential maternity services and specialized providers close to home.”

Hospitals that have permanently closed maternity wards include Centra Southside Community Hospital in Virginia and St Mary’s Sacred Heart Hospital in rural northeastern Georgia. Both mentioned upcoming federal Medicaid policy changes as the reasons for their decisions.

Impact Of Medicaid Cuts On Pregnant Women

Also read: American Academy of Pediatrics Warns Of Raw Milk Risks, Calls For Ban

Medicaid is a major source of health coverage for low-income Americans, paying for approximately 40% of births in the country. Changes to the program could affect hospitals’ finances as well as patients’ ability to receive health coverage.

Although pregnant women are supposed to be exempt from the new work requirements, eligibility rules could still create difficulties for some patients.

Benjamin Sommers, a professor of healthcare economics at Harvard University’s T.H. Chan School of Public Health, said the law would “absolutely” affect pregnant women and pregnancy care facilities.

“It’s not true that this law in any way protects Medicaid for pregnant mothers, for low-income parents. It adds financial strain to the providers and the insurance program that they rely on,” he said.

Sommers warned that some pregnant women are enrolled through Medicaid expansion rather than a pregnancy-specific category. If state authorities do not know that a beneficiary is pregnant, she may not be automatically protected from the new requirements.

“Someone could be enrolled through Medicaid expansion, they could get pregnant and they could mistakenly think – because they heard it on the news that this law doesn’t affect pregnant people – [they’re] fine, and it turns out the state doesn’t know they’re pregnant and they lose coverage."

Rural Communities At Risk

The consequences of maternity unit closures can impact other aspects other than childbirth. Pregnant women may have to travel farther for antenatal appointments, emergency obstetric care and delivery, adding transport costs and making timely treatment more difficult.

March of Dimes has identified 31 rural hospitals with labour and delivery services that could be at risk. If these units close, 96 counties could lose their remaining local delivery services, Jones warned. “Losing these services means fewer places to deliver safely and fewer options for pregnancies requiring specialized care,” she added.

The organisation’s 2026 report found that 34.6% of US counties were maternity care deserts, meaning they had no obstetric clinicians or birthing facilities. These areas are home to approximately 2.4 million women of reproductive age.