“I'm not great at the advice. Can I interest you in a sarcastic comment?”

This is what ‘Friends’ actor Matthew Perry’s character Chandler Bing was known for. He was known for being funny. However, he had his own struggles in his personal life and those struggles were acute depression. He was treating it with ketamine infusion therapy which is legal in the US and the UK.

What is Ketamine infusion therapy?

Ketamine is an anaesthetic used to treat depression, anxiety and pain under supervised and controlled medical settings. However, it does have its side effects, which can lead to distortion of sight, sound and time. It can also produce calming and relaxing effects.

Ketamine increases a person’s heart rate and blood pressure. If overdosed, it can leave users confused and agitated and can cause them to hurt themselves without even realising it. It can also lead to liver damage and bladder problems.

However, when used in moderation and under the supervision of medical doctors, it can treat depression where traditional antidepressants have failed.

Prof Rupert McShane, a University of Oxford psychiatrist who runs an NHS ketamine treatment clinic told BBC that ketamine “probably turns off the area of the brain that is involved in disappointment.”

Can Ketamine Infusion Therapy Kill Someone?

In simple terms, it cannot, be if the dosage is given in a controlled setting and as prescribed. Ketamine infusion therapy uses drugs in small doses than those used for anaesthesia. It acts faster than traditional anti-depressants, but the effects also wear off way quickly. Which is why it is important to monitor patients’ mental state for relapsing back into depression and discouraging them from overdosing on it.

There are ways of giving people ketamine. One of the ways is through “infusing”, which means to use an IV drip. However, injections, nasal sprays and capsules are also methods used to give people ketamine.

Since the dosage of ketamine used in the infusion treatment is small, it being the reason of actor Perry’s death was ruled out. The medical examiner also noted that Perry’s last ketamine infusion therapy session happened more than a week before his death, which means by the time he had died, it must have worn off.

So, What Happened To Perry?

Though Perry’s last session was more than a week before, his post-mortem showed that his blood contained a high concentration of ketamine. He had died of the “acute effects” of ketamine.

If it was not his session, then how did he get ketamine?

Prosecutors alleged that his assistant gave him at least 27 shots of ketamine in four days before his death, reported BBC.

Perry has been open about his personal struggles and this is what the doctors and dealers used against him. Martin Estrada, the US attorney for California’s Central District told the BBC that people took advantage of his condition. They charged him 165 times more than what vials of ketamine cost.

Names that have come up include Dr Salvador Plasencia, drug dealers “Ketamine Queen” aka Jasveen Sangha and Eric Fleming, and Perry’s live-in assistant Kenneth Iwamasa.

Who Are These Names And What Did They Do?

Ketamine Queen or Sangha supplied drugs that led to Perry’s death. Her home was a “drug-selling emporium,” said Estrada. More than 80 vials of ketamine, and thousands of pills including methamphetamine, cocaine and Xanax were allegedly found in her house known as the “Sangha Stash House.”

Sangha is known to deal with high-end celebs and was a “major source of supply for ketamine to others as well as Perry,” said Estrada.

Dr Plasencia called Perry a “moron” while charging him $2,000 for vials that cost only $12. He sold Perry 20 vials of ketamine between September and October 2023, costing $55,000.

He was the one who taught Iwamasa, who had no medical knowledge to inject the drug. This is after he knew that “Perry’s ketamine addiction was spiralling out of control,” as per what the investigators told the BBC.

Another dealer Fleming was told by Sangha to “delete all our messages.” While Fleming pleaded guilty to conspiring to distribute drugs unlawfully, he also allegedly messaged Sangha: “Please call...Got more info and want to bounce ideas off you. I’m 90% sure everyone is protected. I never dealt with [Perry] only his assistant. So the assistant was the enabler.”

The court documents also revealed that he asked Sangha on whether the ketamine stays in your system or “is it immediately flushed out.”

Dr Pepper, Bots, Cans

The people who allegedly exploited Perry used coded language for ketamine and called it “Dr Pepper”, “bots”, or “cans.”

Selling overpriced drugs, taking advantage of Perry’s mental condition and falsifying medical records to make the drugs given to him look legitimate by Dr Plasencia is what took Perry’s life.

Iwamasa is said to have administered more than 20 shots of ketamine and three on the day Perry died. Whereas ketamine is only administered by a physician. Authorities also found that weeks before Perry’s death, Dr Plasencia allegedly bought 10 vials of ketamine and intended to sell to Perry.

He also injected Perry with a large dose, two days later. This caused him to “freeze up” and spiked his blood pressure.

When I Die, I Want Helping Others To Be The First Thing That’s Mentioned

Perry had always been open about his drug addictions, struggles with alcohol and his depression. He said that his openness would help others who are also struggling and wanted to be remembered by his quote which also is on the homepage of the Mattew Perry Foundation that helps others struggling with the disease of addiction: “When I die, I want helping others to be the first thing that’s mentioned.”

Five arrests have been made in the case so far.

Wegovy pill by Novo Nordisk is now under scrutiny after the US Food and Drug Administration (FDA) raised concerns over a television advertisement. FDA said that the commercial includes "false and misleading" claims about the obesity drug's benefits.

In a letter (reported first by Bloomberg) dated February 5, the FDA said the advertisement misbrands the oral weight loss drug. FDA said that it made its distribution a potential violation of federal law. FDA has asked the Danish drugmaker to take immediate corrective action, which include:

• Pulling the ad
• Revising all advertisements that contain misleading statements

Wegovy Pill: FDA Questions Claims of Superiority and Emotional Benefits

As per the letter, the FDA found that the ad misleadingly suggests the Wegovy pill offers superior benefits when compared to other approved GLP-1 weight loss drugs. The regulator flagged phrases such as “live lighter” and “a way forward,” saying they imply greater weight loss and added advantages without evidence to support those claims.

The FDA also took issue with what it describes as emotional and psychological messaging, saying that the ad appears to imply benefits beyond physical weight loss, including emotional relief, reduced psychological burden, hope, or direction in life. FDA notes that this claim positions the drug as a solution to broader life challenges rather than just a treatment to obesity.

Furthermore, FDA said that the ad failed to adequately present risk information in both audio and text formats, which is mandatory requirement for television drug advertising.

Wegovy Pill: Novo Nordisk Responds To FDA Notice

Novo Nordisk confirmed on Monday that it has received the FDA’s letter. The company clarified that while the advertisement has been running since the pill’s launch, it is not linked to its Super Bowl advertising.

“We take all regulatory feedback seriously and are in the process of responding to the FDA to address their concerns regarding the advertisement’s presentation,” said Liz Skrbkova, Novo Nordisk’s head of US media and stakeholder relations, in a statement.

Novo Nordisk is already under pressure to defend its position in the weight loss market, as it is facing a stiff competition from rival Eli Lilly. Furthermore, on Monday, Novo also filed a lawsuit against telehealth company Hims & Hers, seeking to block the mass marketing of compounded versions of its Wegovy pill and injections.

Read: Wegovy Pills Now Available At Your Pharmacies, Here's What To Know About Its Usage

Wegovy Pill: How Effective Is It?

After injection by Novo Nordisk, of the same name, Wegovy, which has been on the market since 2021, its popularity grew so much that it was in short supply until February 2025. The pill version has now come out, which many experts believe will expand its accessibility. As the monthly supply of pill is expected to be cheaper than the monthly supply of the weight loss injection.

A study published in the New England Journal of Medicine show that a 25 milligram Wegovy pill led to 13.6% reduction in weight on average over 64 weeks. When compared to placebo, the result was only 2.2% of weight loss. Novo Nordisk says that those who stayed on the treatment and reduced their calorie intake, it would lead to a loss of 16.6% of their weight.

Wegovy Pill: What Are The Side Effects?

Digestive problems such as nausea and vomiting remain the most common side effects of GLP-1 drugs. These issues were also reported in studies of the pill versions. Around 7 percent of participants taking the Wegovy pill stopped treatment because of side effects, compared with 6 percent in the placebo group. In orforglipron’s trial, up to 10 percent of patients discontinued treatment, compared with 3 percent on placebo.

One key difference lies in how the medications are used. The Wegovy pill must be taken on an empty stomach with a small amount of water. Patients are advised not to eat, drink, or take other medicines for at least 30 minutes afterward. Doctors say this requirement has limited the use of Rybelsus, the pill form of semaglutide approved for diabetes, compared with Ozempic.

Two years before Jeffrey Epstein killed himself in his New York jail cell, he claimed that US President Donald Trump may be suffering from dementia.

The United States Department of Justice recently released more of the harrowing Epstein Files that lift the lid on years' worth of horrific crimes committed by the convicted American child sex offender, serial rapist and human trafficker.

Among the files, eagle eyed readers found an email sent to journalist and Trump biographer Michael Wolff on Dec. 29, 2017, where Epstein claimed that Trump has begun showing signs of memory loss during his first presidency after he failed to recognize some of his own friends.

In the email to the Landslide author, the convict wrote: "Some at dinner with donald last night, were concerned about dementia. tons of makeup. did not recognize old friends.”

And Epstein isn't alone. Former White House chief strategist and Trump associate, Steve Bannon allegedly believed the president had "early-stage dementia," according to former 60 Minutes producer Ira Rosen’s book Ticking Clock.

Bannon claimed that Donald “had no attention span, didn't read, and now doesn't listen. He said Donald repeats himself a lot, telling the same story minutes after he told it before," per Rosen's account, which the former chief strategist later denied.

The producer also claimed in the book that “Bannon tried to build support to have Trump removed” from office due to his concerns.

Family Members Say Trump Has Dementia

Mary Trump, a well-known critic of her uncle who frequently speaks about him on her YouTube channel, has implied that he could be suffering from Alzheimer's disease, noting similarities to her late grandfather, who also suffered from the neurodegenerative disease.

As per UK Express, Mary highlighted that she has seen resemblances to Fred Trump, Donald's late father and former real estate magnate, who battled Alzheimer’s before passing away in 1999 at the age of 93.

Speaking last year, Mary recounted witnessing her grandfather’s decline and suggested that Donald sometimes doesn’t seem “oriented,” pointing to a particular look. Talking about her grandfather, she told New York Magazine: "One of the first times I noticed it was at some event where he was being honored. And I looked at him and saw this deer-in-the-headlights look, like he had no idea where he was."

In further remarks, Mary said she now notices what the publication described as “flashes” of her grandfather in her uncle when she sees him on stage, pointing out the same “deer-in-the-headlights” expression.

She added: "Sometimes it does not seem like he's aware of time or place. And on occasion, I do see that deer-in-the-headlights look."

Trump Rejects Memory Loss Claims

Despite multiple reports, Trump and his team have consistently rejected such claims, noting that he has “aced” three cognitive tests and there is no possibility of him having Alzheimer's disease.

In a conversation with the New York Magazine, Trump also reflected on his father’s diagnosis: "He had one problem. At a certain age, about 86, 87, he started getting what do they call it?"

His press secretary, Karoline Leavitt, supplied the term for Trump, who referred to it as an “Alzheimer’s thing,” asserting that he did not “have it.” The health of the 79-year-old has been the subject of much public speculation recently, with observers noting bruises on his hands, what appear to be swollen ankles, and rambling speech.

READ MORE: New FDA Approved Blood Test Can Predict Alzheimer’s Disease Before Symptoms Appear

What Is Alzheimer’s Disease?

Alzheimer's disease is one of the most common forms of dementia and mostly affects adults over the age of 65.

About 8.8 million Indians aged 60 and above are estimated to being living with Alzheimer's disease. Over seven million people in the US 65 and older live with the condition and over 100,00 die from it annually.

Alzheimer's disease is believed to be caused by the development of toxic amyloid and beta proteins in the brain, which can accumulate in the brain and damage cells responsible for memory.

Amyloid protein molecules stick together in brain cells, forming clumps called plaques. At the same time, tau proteins twist together in fiber-like strands called tangles. The plaques and tangles block the brain's neurons from sending electrical and chemical signals back and forth.

Over time, this disruption causes permanent damage in the brain that leads to Alzheimer's disease and dementia, causing patients to lose their ability to speak, care for themselves or even respond to the world around them.

While there is no clear cause of Alzheimer's disease, experts believe it can develop due to genetic mutations and lifestyle choices, such as physical inactivity, unhealthy diet and social isolation.

Early symptoms of Alzheimer's disease include forgetting recent events or conversations. Over time, Alzheimer's disease leads to serious memory loss and affects a person's ability to do everyday tasks.

There is no cure to this progressive brain disorder and in advanced stages, loss of brain function can cause dehydration, poor nutrition or infection. These complications can result in death.

Health officials in Washington, D.C. are warning that confirmed cases of measles may have spread during this year’s National March for Life rally and related events held in the capital late January. The annual anti-abortion gathering drew thousands of people to the National Mall and surrounding areas, raising concerns about potential large-scale exposure.

The D.C. Department of Health said it is actively working to identify individuals who may be at risk after learning that several people who later tested positive for measles were present in the city while contagious.

“DC Health was notified of multiple confirmed cases of measles whose carriers visited multiple locations in the District while contagious,” the agency said in a statement on Sunday. Officials are now contacting people who were at those locations during the exposure window.

Measles In DC: Transit Hubs and Campuses Among Exposure Sites

According to DC Health, potential exposure sites span a wide range of busy public locations between January 21 and February 2. These include Ronald Reagan Washington National Airport, Union Station, an Amtrak Northeast Regional train, and multiple stops within the city’s Metro subway system.

Health officials also flagged visits to the Basilica of the National Shrine of the Immaculate Conception and Catholic University as part of the exposure timeline. Given the volume of visitors moving through these spaces daily, authorities say the risk of wider spread cannot be ruled out.

Measles In DC: Hospital Issues Public Health Notice

Children’s National Hospital has also issued a public health notice after a confirmed measles patient from Virginia visited its Emergency Department on February 2 while infectious. The hospital said it is coordinating with public health authorities to identify and notify anyone who may have been exposed during that time.

Measles is highly contagious and can remain airborne for up to two hours after an infected person leaves an area, making hospital settings particularly vulnerable.

Measles In DC: Surge Across the United States

The situation in Washington comes as the United States faces its largest measles outbreak in decades. According to the Centers for Disease Control and Prevention, 733 confirmed cases have been reported across 20 states so far this year. The CDC says about 95 percent of those cases involve people who were unvaccinated or whose vaccination status is unknown.

South Carolina remains one of the hardest-hit states. Its outbreak began in October 2025 and has now surpassed earlier outbreaks elsewhere in the country. State health officials reported 44 new cases on Friday, bringing the total to 920. While the pace of new cases has slowed slightly, officials continue to warn of possible exposure at public places such as a Target store in Taylors and a Social Security Administration office in Spartanburg, where the outbreak is centered.

Measles In DC: Vaccination Urged Amid Global Concern

Speaking on CNN’s State of the Union, Centers for Medicare and Medicaid Services Administrator Mehmet Oz urged Americans to get vaccinated against measles. While recent federal policy changes have rolled back recommendations for some vaccines, guidance on measles immunization remains unchanged.

International health authorities are also watching closely. The World Health Organization’s Pan American Health Organization has invited U.S. officials to a meeting in April to review the country’s measles elimination status, which is now under threat.

D.C. health officials are urging anyone who may have been exposed and is not fully vaccinated, pregnant, or immunocompromised to contact a healthcare provider immediately.