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After mpox outbreak, Africa is under the threat of yet another virus outbreak, this is the Marburg virus outbreak in Rwanda. So far, six people have died from the outbreak, confirmed the health minister. Most victims were the healthcare workers in the hospital's intensive care unit. As per reports, 20 cases have been identified since the outbreak was confirmed on Friday.
With the fatality rate of 8% it is the same virus family as Ebola. The main carrier is from fruit bats which spreads to humans then through the contact of bodily fluids of infected individuals, it spreads to others.
The common signs and symptoms of the Marburg virus include fever, pain, diarrhoea, vomiting and in the case of extreme blood loss, death too can happen.
So far, there is no specific treatment or vaccine for the virus. However, treatments like drugs and immune therapy are being developed as per the World Health Organisation (WHO).
Rwanda says that it has intensified its contact tracing, surveillance and testing to contain the spread. It has also tracked about 300 people who had come into contact with individuals affected by the Marburg virus.
The health minister has urged people to stay vigilant and avoid any physical contact and to wash their hands with clean water, soap or sanitiser and report any suspected case.
As of now, most of the cases have spread to the capital in Kigali. In light of this, the US Embassy in the city has advised its employees to work remotely for the next week.
This is the first time Rwanda has confirmed for Marburg cases, before this, in 2023, Tanzania confirmed the outbreak, whereas three people had died of this in Uganda in 2017.
As per WHO, this virus kills half of the people it infects. In the previous outbreaks, it has killed between 24% to 88% of the patients.
The virus was first detected in 1976 after 31 people were infected, out of which 7 died in simultaneous outbreak in Marburg and Frankfurt in Germany, and Belgrade in Serbia.
The source was traced to African green monkeys who were imported from Uganda. However, other animals too are linked to the virus spread, including bats.
In the past, the virus outbreaks have happened in countries like Equatorial Guinea, Ghana, the Democratic Republic of the Congo, Kenya, South Africa, Uganda, and Zimbabwe. In 2005, this virus killed 300 people in Angola.
However, for the rest of the world, only two people have died from the virus in the rest of the world, with one of them being in Europe, and the other in the US. These both have been on expeditions to caves in Uganda.
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Kratom is a plant-based product sometimes used as a natural way to boost energy, manage pain or ease opioid withdrawal. It is is showing up frequently among patients in addiction clinics across the US.
According to STAT, at Boulder Care, a telehealth addiction clinic, the number of new patients using kratom increased from 3% in September 2025 to 8% in July 2026, before reaching 14% in August.
Clinicians say the growing problem is not only traditional kratom leaf. Increasingly, patients are using products containing high concentrations of 7-hydroxymitragynine, or 7-OH, a potent compound associated with opioid-like effects.
Dr Ayesha Appa, head of medical affairs at Boulder Care described "the increase as quite an explosion.”
Kratom is made from the leaves of the Mitragyna speciosa tree, which is found in Southeast Asia. The leaves have traditionally been used for their stimulant and pain-relieving effects. They are now sold in the US as powders, capsules, teas, extracts and other products.
At lower doses, kratom can produce stimulant-like effects, including increased alertness and energy. At higher doses, its effects can become more sedating and produce opioid-like effects.
The plant's main alkaloid is mitragynine. Another compound, 7-OH, occurs naturally in trace amounts in kratom leaf.
Kratom can interact with opioid receptors in the brain, which are involved in pain, reward and dependence. Regular use can therefore make the brain adapt to the substance.
When someone who has developed dependence suddenly stops taking it, withdrawal symptoms can occur, like irritability, restlessness, muscle aches, fatigue, sweating and other flu-like symptoms.
The FDA says epidemiological evidence suggests that some people develop substance use disorder after using kratom, although it also notes that the abuse potential of kratom has not been fully characterised in well-designed human studies.
Also read: Warning Letter Sent To Companies Selling Illegal Opioid Compound
7-OH is different from the small amounts naturally present in ordinary kratom leaf. Some products now sold as kratom contain concentrated 7-OH, including tablets, gummies, drink shots and other products.
The FDA describes these products as potent opioids, warning that they have not been proven safe or effective for any medical use.
The American College of Medical Toxicology says clinical experience has linked 7-OH with opioid-like effects, including intoxication, respiratory depression, dependence and withdrawal.
CDC data show that kratom-related poison-center reports increased dramatically over the past decade. US poison centers recorded 3,434 kratom exposure reports in 2025, compared with 258 in 2015, an approximately 1,200% increase. Hospitalisations following single-substance kratom exposures also rose from 43 in 2015 to 538 in 2025.
The shift toward concentrated products is another concern. Poison Centers reported 901 exposures involving 7-OH between January and June 2026, compared with 593 during all of 2025.
Traditional kratom leaf contains a mixture of naturally occurring alkaloids, including mitragynine and small amounts of 7-OH. Commercial 7-OH products can contain far higher concentrations of the compound.
The stronger products may produce more pronounced opioid-like effects and carry greater risks of dependence and withdrawal.
Kratom is also not an FDA-approved treatment for pain, opioid withdrawal or any other medical condition. Its long-term effects remain vague.
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The US measles outbreak is showing no signs of slowing down as it has reached new locations. A new case was recently reported in Wisconsin's Chippewa County, outside the state's main southwestern outbreak area, while Philadelphia health officials are warning of a possible measles exposure at the city's international airport.
The developments are crucial as measles cases continue to increase across the US, with Pennsylvania reporting hundreds of cases and Wisconsin recording 171 confirmed cases so far in 2026.
Wisconsin's Department of Health Services confirmed one measles case in Chippewa County on September 22. According to reports, the case has been attributed to out-of-state travel.
It means that it may not be connected to southwestern Wisconsin outbreak, where cases are concentrated. The state said no public exposure sites have been identified so far. The Chippewa County Health Department is working with the infected person and healthcare providers to identify anyone who may have been exposed.
“Measles is highly contagious, so confirming a case in our community is concerning,” Chippewa County Health Officer Brittnay Herrick said. “Our public health team is working closely with partners to identify potential exposures and ensure those affected have the information and guidance they need.”
Wisconsin has reported cases in Grant, Iowa, Lafayette, Marathon and Vernon counties since August. The state's largest cluster remains in southwestern Wisconsin, where 161 confirmed and six possible cases had been reported by September 18.
On the other hand, Philadelphia health officials are also warning travelers about a separate possible measles exposure at Philadelphia International Airport. According to health officials, an infected person walked through Terminals B and F, as well as areas connecting to Terminals C, D and E, between 7:25 p.m. on September 13 and 12:05 a.m. on September 14.
The person remained inside the airport and did not leave the premises. Health officials said the airport exposure is not connected to a separate measles exposure reported recently at Children's Hospital of Philadelphia.
Philadelphia Health Commissioner Dr. Palak Raval-Nelson said, “This week's measles exposures are a reminder of how important it is for all of us to be up to date on our vaccinations.” She added that fully vaccinated people are not at high risk from the suspected exposures.
People who were at the airport during the exposure period are being advised to check whether they are immune.
Those who are unvaccinated or unsure of their vaccination status, along with infants, pregnant people who are not immune and people with weakened immune systems, should contact a healthcare provider.
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Measles is among the most contagious infectious diseases. The virus spreads through the air when an infected person coughs, sneezes or breathes, and can remain in the air for up to two hours after the person has left an area.
Early symptoms typically include fever, cough, runny nose and red, watery eyes, followed several days later by a characteristic rash. Serious complications can include pneumonia, brain inflammation and, in some cases, death.
The Philadelphia Health Department says measles can be transmitted from four days before through four days after the rash appears, meaning an infected person can spread the virus before realizing they have measles.
People who may have been exposed should first find out if they are immune. Two documented doses of the MMR vaccine provide strong protection against measles. People who are not immune may be eligible for post-exposure treatment, depending on when the exposure happened.
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The Trump administration has canceled Obamacare health insurance enrollments covering more than 760,000 people, claiming the policies were linked to unauthorized enrollment. The move is part of a crackdown on fraud in the Affordable Care Act Marketplace.
The Centers for Medicare & Medicaid Services (CMS) said it canceled approximately 315,000 Marketplace enrollments on August 31, after investigations with insurers confirmed that the enrollments were unauthorized. The agency estimates that it will return about $2.2 billion in federal premium subsidies.
The administration is also investigating another 419,000 to 450,000 enrollees to determine whether they meet citizenship or immigration and income requirements. These people have not been found ineligible yet and are undergoing additional verification.
The authorities says it is targeting fraudulent, unauthorized and improper enrollments, rather than trying to eliminate Obamacare coverage itself.
CMS said it found that some people were enrolled without their knowledge, while others had unresolved identity, citizenship or immigration-status information. The agency also found applications missing information such as Social Security numbers.
Vice President JD Vance said the canceled group includes “a mix of both phantom people, but also real people who just don’t meet the eligibility requirements,” including some people who he said were enrolled by brokers without their knowledge.
CMS Administrator Mehmet Oz said some enrollees were classified as “phantoms” because officials believe they either did not exist or did not know they had coverage.
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The administration says the 760,000 people were covered by enrollments that CMS determined were unauthorized. But it does not mean every individual has committed fraud.
Some cases involve alleged actions by insurance agents or brokers. CMS says it found applications submitted without required applicant information and evidence that some consumers may have been enrolled without their authorization.
CMS has issued notices to 569 agents and brokers that it intends to terminate their agreements over applications that allegedly lacked key information. The agency says 66 had already received termination notices.
The administration has identified another group of approximately 419,000 to 450,000 people for additional verification.
Officials say they want to establish whether these enrollees are legally eligible for Marketplace coverage and whether they meet the income requirements for the federal subsidies.
CMS says newly registered brokers for the 2026 plan year accounted for a disproportionate share of the fraudulent Obamacare enrollments.
According to the agency, enrollments handled by these newer brokers were 2.8 times more likely to have unresolved income-verification issues, 2.7 times more likely to be missing Social Security numbers and 2.6 times more likely to have unresolved citizenship or immigration-status verification issues compared with brokers registered before 2026.
CMS has therefore imposed a temporary moratorium on new broker registrations for the 2027 plan year for agents and brokers without an active 2026 Exchange Agreement.
The move does not end the Affordable Care Act or eliminate Marketplace insurance. Instead, it represents a major tightening of how the federal government verifies who is enrolled and who qualifies for subsidies.
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