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After mpox outbreak, Africa is under the threat of yet another virus outbreak, this is the Marburg virus outbreak in Rwanda. So far, six people have died from the outbreak, confirmed the health minister. Most victims were the healthcare workers in the hospital's intensive care unit. As per reports, 20 cases have been identified since the outbreak was confirmed on Friday.
With the fatality rate of 8% it is the same virus family as Ebola. The main carrier is from fruit bats which spreads to humans then through the contact of bodily fluids of infected individuals, it spreads to others.
The common signs and symptoms of the Marburg virus include fever, pain, diarrhoea, vomiting and in the case of extreme blood loss, death too can happen.
So far, there is no specific treatment or vaccine for the virus. However, treatments like drugs and immune therapy are being developed as per the World Health Organisation (WHO).
Rwanda says that it has intensified its contact tracing, surveillance and testing to contain the spread. It has also tracked about 300 people who had come into contact with individuals affected by the Marburg virus.
The health minister has urged people to stay vigilant and avoid any physical contact and to wash their hands with clean water, soap or sanitiser and report any suspected case.
As of now, most of the cases have spread to the capital in Kigali. In light of this, the US Embassy in the city has advised its employees to work remotely for the next week.
This is the first time Rwanda has confirmed for Marburg cases, before this, in 2023, Tanzania confirmed the outbreak, whereas three people had died of this in Uganda in 2017.
As per WHO, this virus kills half of the people it infects. In the previous outbreaks, it has killed between 24% to 88% of the patients.
The virus was first detected in 1976 after 31 people were infected, out of which 7 died in simultaneous outbreak in Marburg and Frankfurt in Germany, and Belgrade in Serbia.
The source was traced to African green monkeys who were imported from Uganda. However, other animals too are linked to the virus spread, including bats.
In the past, the virus outbreaks have happened in countries like Equatorial Guinea, Ghana, the Democratic Republic of the Congo, Kenya, South Africa, Uganda, and Zimbabwe. In 2005, this virus killed 300 people in Angola.
However, for the rest of the world, only two people have died from the virus in the rest of the world, with one of them being in Europe, and the other in the US. These both have been on expeditions to caves in Uganda.
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Being infected with SARS-CoV-2 two or more times may be associated with a higher likelihood of developing new health conditions. According to a study published in Canada Communicable Disease Report, repeated COVID-19 infections were associated with higher odds of new diagnoses, including respiratory, back and mental health problems.
It is well known that pre-existing health conditions can increase the risk of severe COVID-19. But the new research suggests that the relationship between COVID-19 and chronic health conditions may run in both directions.
The findings reinforce “the continued importance of public health efforts to prevent infection,” the researchers said.
For the study, researchers from the Public Health Agency of Canada and Statistics Canada analysed data collected between April 2022 and June 2023 from nearly 9,000 respondents to the Canadian COVID-19 Antibody and Health Survey and Follow-up Questionnaire.
Also read: COVID-19 Rising In 35 US States: Sore Throat, Diarrhea Among Key Symptoms
Nearly 50% of participants reported having one COVID-19 infection, while about 20% reported two or more infections.
The researchers found that people who reported two or more infections had 76% higher odds of receiving a new diagnosis than those who reported no infections.
The new health conditions included:
People with repeat infections had five times the odds of receiving a respiratory diagnosis and nearly four times the odds of developing back problems.
Participants who experienced acute symptoms that interfered with daily activities during their first infection were also 63% more likely to receive a new diagnosis.
Those who experienced symptoms three or more months after an infection had more than three times the odds of receiving a new diagnosis.
The researchers cautioned that the health information was self-reported, which means participants may not have accurately remembered the severity of their symptoms.
In addition, some people who reported having no infections may have had asymptomatic or undiagnosed COVID-19.
“Continued investigation into the long-term sequelae of SARS-CoV-2 infections, particularly reinfections, and the biological, behavioral and systemic factors that may mediate the effects of these infections is needed,” said the researchers in the paper.
“Such investigations could assist healthcare practitioners in tailoring COVID-19 vaccine recommendations and post-COVID-19 monitoring for new health conditions and guide public health practice and messaging when promoting COVID-19 vaccine uptake and personal protective measures (e.g., masking) to prevent and minimize the severity of infections, as well as the potential development of new health conditions,” they added.
Global COVID-19 transmission has experienced a distinct late-summer wave through August and September 2026. Several countries, including Canada, the US, South Korea and Japan, have reported increased COVID-19 activity.
The current circulation includes variants such as XFG (Stratus), BA.3.2 (Cicada), LF.7 and NB.1.8.1 (Nimbus). The continued circulation of SARS-CoV-2 and the possibility of repeat infections make research into the longer-term health effects of reinfection particularly relevant.
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Nearly 3 in 4 US adults felt very tired or exhausted on at least some days, according to a recent Centers for Disease Control and Prevention (CDC) survey.
The report from the National Center for Health Statistics (NCHS) analyzed data from the 2024 National Health Interview Survey, which included approximately 27,000 adults aged 18 and older.
Fatigue is generally defined as physical or mental tiredness or exhaustion that does not improve with additional sleep or rest.
However, it should be distinguished from sleepiness, which is the experience of feeling drowsy or having difficulty staying awake, the report stated.
About 1 in 6 adults experienced frequent fatigue, defined as feeling very tired or exhausted on “most days” or “every day.”
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The report showed that among adults with frequent fatigue, 69.6% reported symptoms of anxiety, 46.1% reported cognition difficulty and 45% reported symptoms of depression.
Compared with adults without frequent fatigue, those with frequent fatigue were more than three times as likely to have symptoms of depression, more than twice as likely to have cognition difficulty and twice as likely to report symptoms of anxiety.
Fatigue also affected work and social activities, with 36% of adults with frequent fatigue reporting work limitations, compared with 15.3% of those without frequent fatigue.
Meanwhile, 16.2% of adults with frequent fatigue reported some difficulty with social activities, compared with 5.3% of those without frequent fatigue.
Another 12.8% reported a lot of difficulty with social activities or said they could not engage in them at all, compared with 2.6% of adults without frequent fatigue.
“Fatigue is one of the most frequently reported health concerns in primary care,” Natalie A.E. Young, the report’s author, said.
She added that people who report regular fatigue “are at higher risk of activity limitations and disability, including permanent work disability,” while pointing out that there had not been much attention to the frequency of general fatigue symptoms in the US adult population.
While fatigue symptoms can be associated with various conditions, Young noted that some may not be linked to a specific medical condition.
“Stress can cause surges in hormones like cortisol and adrenaline, which can wear a body down. That increasing stress contributes to an uptick in fatigue,” Jennifer Caspari, a clinical psychologist licensed in Denver and Vancouver, British Columbia, was quoted as saying to NBC News.
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Pennsylvania has reported a third measles-related death amid an expanding outbreak that has infected hundreds of people across the state. The latest casualty involved a 40-year-old woman.
The woman, a resident of Jefferson County, died on Saturday from complications associated with measles, according to the county coroner. The case is now being reviewed by the Pennsylvania Department of Health.
The death comes as Pennsylvania's measles outbreak continues to expand. As of September 11, the state had recorded 676 confirmed cases across 37 counties, including 124 hospitalisations.
Measles is often perceived as primarily a childhood infection. The latest fatality of the 40-year-old reminds us that measles is not just a childhood disease.
“Many people associate measles with a childhood illness, but it can lead to severe complications in individuals of any age,” Jason Stiver, Jefferson County's chief deputy coroner and public relations officer, told WTAE.
He added, “Measles is highly contagious and can result in serious respiratory illness, hospitalization, and in rare cases like this, death. We encourage residents to stay informed, follow guidance from public health officials, and take appropriate steps to protect themselves and their families.”
The two earlier Pennsylvania deaths occurred in August and involved infants in Lancaster County. One infant died from measles infection, while the other died from a ruptured spleen, with measles listed as a significant contributing condition.
Neither infant was old enough to receive the routine measles vaccine, which is generally first given around 12 months of age.
Measles is among the world's most contagious infectious diseases. It spreads through respiratory droplets and airborne particles when an infected person coughs, sneezes or breathes.
The Pennsylvania Department of Health says two doses of the measles, mumps and rubella (MMR) vaccine are 97% effective at preventing measles. The state has identified four breakthrough infections among appropriately vaccinated people during the current outbreak.
The outbreak has been particularly concentrated in Lancaster and Mifflin counties, although infections have now been reported across more than half of Pennsylvania's counties.
The health department previously warned that nearly 20% of people who contract measles may require hospitalisation, while measles-related death occurs in roughly one to three people per 1,000 cases. Complications include pneumonia and inflammation of the brain.
Also read: World Leaders Call For Obesity & NCD Prevention At BRICS 2026 Summit: Why Focus Is Growing?
There is also an ongoing dispute over how measles-related deaths are being counted nationally. Pennsylvania health officials have counted three deaths as measles-associated in 2026.
However, the CDC's national data currently does not include these deaths, and as of September 10 it reported 3,294 confirmed measles cases in the US without listing a measles death in 2026.
Pennsylvania officials are reviewing the latest death using the state's epidemiological definition for a measles-associated death, which has also been shared with the CDC and the Council of State and Territorial Epidemiologists.
Measles was eliminated from the US in 2000. But the growing outbreak is a reminder that elimination does not mean the virus can never return. Sustained high vaccination coverage remains critical to preventing further infections.
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