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After mpox outbreak, Africa is under the threat of yet another virus outbreak, this is the Marburg virus outbreak in Rwanda. So far, six people have died from the outbreak, confirmed the health minister. Most victims were the healthcare workers in the hospital's intensive care unit. As per reports, 20 cases have been identified since the outbreak was confirmed on Friday.
With the fatality rate of 8% it is the same virus family as Ebola. The main carrier is from fruit bats which spreads to humans then through the contact of bodily fluids of infected individuals, it spreads to others.
The common signs and symptoms of the Marburg virus include fever, pain, diarrhoea, vomiting and in the case of extreme blood loss, death too can happen.
So far, there is no specific treatment or vaccine for the virus. However, treatments like drugs and immune therapy are being developed as per the World Health Organisation (WHO).
Rwanda says that it has intensified its contact tracing, surveillance and testing to contain the spread. It has also tracked about 300 people who had come into contact with individuals affected by the Marburg virus.
The health minister has urged people to stay vigilant and avoid any physical contact and to wash their hands with clean water, soap or sanitiser and report any suspected case.
As of now, most of the cases have spread to the capital in Kigali. In light of this, the US Embassy in the city has advised its employees to work remotely for the next week.
This is the first time Rwanda has confirmed for Marburg cases, before this, in 2023, Tanzania confirmed the outbreak, whereas three people had died of this in Uganda in 2017.
As per WHO, this virus kills half of the people it infects. In the previous outbreaks, it has killed between 24% to 88% of the patients.
The virus was first detected in 1976 after 31 people were infected, out of which 7 died in simultaneous outbreak in Marburg and Frankfurt in Germany, and Belgrade in Serbia.
The source was traced to African green monkeys who were imported from Uganda. However, other animals too are linked to the virus spread, including bats.
In the past, the virus outbreaks have happened in countries like Equatorial Guinea, Ghana, the Democratic Republic of the Congo, Kenya, South Africa, Uganda, and Zimbabwe. In 2005, this virus killed 300 people in Angola.
However, for the rest of the world, only two people have died from the virus in the rest of the world, with one of them being in Europe, and the other in the US. These both have been on expeditions to caves in Uganda.
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The UK Health Security Agency (UKHSA) has declared a national outbreak of Salmonella in the UK, with health officials suspecting a possible link to imported eggs.
According to the UKHSA, 207 confirmed cases were detected between August 11, 2025, and August 1, 2026, with the majority reported in 2026. Of those affected, 38% were admitted to hospital, and one person has died.
Cases have been reported across the UK:
Among cases in England, London reported 47 cases, the highest number, followed by Yorkshire and the Humber with 38 cases.
The UKHSA identified an increase in Salmonella Enteritidis infections caused by a single strain through whole-genome sequencing (WGS) data.
The agency has launched an investigation to identify the source of the outbreak. Initial findings suggest that the outbreak may be linked to eggs imported from outside the UK. However, the source has not been definitively established, and investigations are continuing.
Dr Kathleen O'Reilly, Associate Professor at the London School of Hygiene & Tropical Medicine, said the investigation involves identifying additional cases and examining possible common sources of infection.
Dr Damien Tully, Associate Professor at the Medical Research Council at LSHTM's Uganda Research Unit, added that the number of confirmed cases is likely to be “just the tip of the iceberg.”
Salmonella is a bacterial infection that commonly causes diarrhea and gastrointestinal illness.
Common symptoms include:
Salmonella is generally a self-limiting infection. However, young children, older adults and people with weakened immune systems can develop more severe complications.
These may include bloodstream infections, infections at other sites, sepsis and multiorgan failure.
The UKHSA stated that Salmonella Enteritidis is the most common Salmonella serovar in England and a leading cause of salmonellosis.
Like other non-typhoidal Salmonella infections, it can spread through contaminated food, including:
The bacteria can also spread through contact with contaminated environments or from person to person.
Dr O'Reilly advised fully cooking eggs before eating them and maintaining good food hygiene.
Key precautions include:
People who develop diarrhea or stomach cramps should rest and drink plenty of fluids. Young children, older adults and other vulnerable people who become ill should seek medical advice.
The US is also experiencing a Salmonella outbreak linked to eggs. The US Food and Drug Administration (FDA) upgraded the recall to its highest risk level and classified nearly 1.6 million dozen eggs as “Class I.” The agency defines a Class I recall as a situation in which there is a reasonable probability that exposure to the affected product could cause serious adverse health consequences or death.
The FDA said illness usually occurs 12 to 72 hours after consuming food contaminated with Salmonella, with symptoms typically lasting four to seven days.
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For people living with alopecia areata, hair loss can be unpredictable, persistent, and difficult to treat. Now, amid lack of a definitive cure, a medicine originally developed for inflammatory diseases such as rheumatoid arthritis, is showing striking results in patients with severe alopecia areata.
Two large Phase III clinical trials involving 1,399 adults and adolescents found that the drug upadacitinib significantly improved scalp hair regrowth compared with placebo. The trial’s findings were published in JAMA Dermatology.
The results are both striking and promising as alopecia areata is an autoimmune condition, in which the immune system mistakenly attacks hair follicles.
Upadacitinib, sold under the brand name Rinvoq, belongs to a class of medicines called JAK inhibitors.
JAK proteins help transmit signals that are involved in immune and inflammatory responses. In alopecia areata, abnormal immune response contributes to the attack on hair follicles.
By blocking JAK1 signaling, upadacitinib can slow down some of these immune responses, potentially allowing damaged or suppressed hair follicles to resume producing hair for some time.
The drug is already used for other autoimmune conditions including rheumatoid arthritis, Crohn's disease and ulcerative colitis.
Its potential use in alopecia is an example of drug repurposing, where an existing medicine gets used for a completely different disease.
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The Phase III programme included two parallel trials, UP-AA1 and UP-AA2, involving adults and adolescents with severe alopecia areata.
After 24 weeks, about 45% of patients taking 15 mg of upadacitinib achieved at least 80% scalp hair coverage. More than 54% of those taking 30 mg reached the same threshold.
In comparison, only about 2% of placebo recipients achieved that level of regrowth.
Researchers also reported improvements in eyebrow and eyelash hair and indirectly in quality of life
Strikingly, benefits were seen in people with severe disease, rather than only those with a few small bald patches. Severe alopecia areata in the trials was defined as hair loss affecting at least half of the scalp.
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Alopecia areata currently has no guaranteed permanent cure. And this trial does not mean that the condition can be cured.
The disease can follow a relapsing and unpredictable course, with hair growing back and then falling out again.
The new findings show that upadacitinib can promote substantial hair regrowth while patients are receiving treatment. They do not prove that the underlying autoimmune disease can be permanently eliminated.
There are already approved JAK inhibitors for alopecia areata, including baricitinib, ritlecitinib and deuruxolitinib, so upadacitinib would not be the first drug in this category.
The safety findings in the trials were consistent with the known safety profile of upadacitinib, and researchers reported no new safety concerns during the study period.
Common adverse events included upper respiratory infections, acne, increased creatine phosphokinase and nasopharyngitis.
But JAK inhibitors are powerful medicines that regulates immune system and are not something people should take simply because they are experiencing hair loss. Their risks and benefits need to be assessed by a doctor.
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The Karnataka government has launched a QR code-based grievance system that allows consumers to lodge food and drug safety complaints directly with authorities. The move is aimed at making food and drug safety-related violations easier to report.
The Integrated Public Grievance Redressal System (IPGRS) was launched by Karnataka Health Minister U T Khader on August 17. The system has been developed by the state’s Food Safety and Drugs Administration (FSDA) in coordination with the Centre for e-Governance.
QR codes will be displayed at hotels, restaurants, eateries and drug stores, allowing customers to scan them and register complaints. They will also be able to track the status of complaints, according to officials.
The system is designed to cover both food and medicine-related violations. For food establishments, consumers can report:
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The QR system comes as Karnataka's food safety authorities ramp up inspections across the state. In one recent operation, inspections at government facilities reportedly uncovered food safety problems, while canteens at Vidhana Soudha and the health department headquarters in Bengaluru were sealed after officials found expired food and unhygienic conditions, including cockroaches.
The move came after complaints about unhygienic food handling and the use of artificial colours in shawarma and kebabs.
During the checks, 61 samples were collected, with nine shawarma samples and one kebab sample subsequently declared unsafe. Officials said legal action is now being initiated against those responsible.
The department also turned its attention to food warehouses used by e-commerce platforms, inspecting 236 facilities and initiating proceedings against 44 for violations. Eight of these warehouses were fined a total of Rs 1.97 lakh after officials found unhygienic conditions.
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Concerns were also raised over milk and dairy products entering the state. Of the 25 samples collected from batches coming into Karnataka from Tamil Nadu, one was found to be substandard.
In Bengaluru Urban, inspection teams visited more than 60 three- and five-star hotels, eight warehouses and four international restaurants.
The inspections also uncovered large quantities of expired, spoiled and improperly labelled food. Officials seized 429 kg of mutton and chicken, 203 kg of fish, and 200 kg of vegetarian food that had been stored alongside non-vegetarian items.
The seized material also included 76 kg of rotten or mouldy vegetables, 45 litres of expired milk and curd, and 12 kg of expired bakery products. Another 67 kg of cereals and other food products were confiscated for being expired or mislabelled, while 49 litres of used or non-compliant cooking oil were also seized.
Traditionally, consumers had to go through a complex complaint-lodging process to report an unsafe restaurant, suspicious food product or expired or harmful medicines. The new system essentially puts a digital window to lodge complaints right at the place where the problem is discovered.
A customer who notices poor hygiene at a restaurant, for example, can scan the QR code displayed at the establishment and submit the complaint without having to separately search for the relevant authority. The system is also intended to make complaints easier for officials to monitor and follow up on.
The state government has described the initiative as the first of its kind in India, with the system integrated with the government's Centre for e-Governance.
That could become particularly useful in a state where food is sold through a huge network of restaurants, street vendors, hotels, pharmacies and institutional kitchens.
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