After mpox outbreak, Africa is under the threat of yet another virus outbreak, this is the Marburg virus outbreak in Rwanda. So far, six people have died from the outbreak, confirmed the health minister. Most victims were the healthcare workers in the hospital's intensive care unit. As per reports, 20 cases have been identified since the outbreak was confirmed on Friday.

What Is Marbug Virus?

With the fatality rate of 8% it is the same virus family as Ebola. The main carrier is from fruit bats which spreads to humans then through the contact of bodily fluids of infected individuals, it spreads to others.

Common Signs And Symptoms

The common signs and symptoms of the Marburg virus include fever, pain, diarrhoea, vomiting and in the case of extreme blood loss, death too can happen.

So far, there is no specific treatment or vaccine for the virus. However, treatments like drugs and immune therapy are being developed as per the World Health Organisation (WHO).

Call Of Action

Rwanda says that it has intensified its contact tracing, surveillance and testing to contain the spread. It has also tracked about 300 people who had come into contact with individuals affected by the Marburg virus.

The health minister has urged people to stay vigilant and avoid any physical contact and to wash their hands with clean water, soap or sanitiser and report any suspected case.

As of now, most of the cases have spread to the capital in Kigali. In light of this, the US Embassy in the city has advised its employees to work remotely for the next week.

This is the first time Rwanda has confirmed for Marburg cases, before this, in 2023, Tanzania confirmed the outbreak, whereas three people had died of this in Uganda in 2017.

History Of Marburg

As per WHO, this virus kills half of the people it infects. In the previous outbreaks, it has killed between 24% to 88% of the patients.

The virus was first detected in 1976 after 31 people were infected, out of which 7 died in simultaneous outbreak in Marburg and Frankfurt in Germany, and Belgrade in Serbia.

The source was traced to African green monkeys who were imported from Uganda. However, other animals too are linked to the virus spread, including bats.

In the past, the virus outbreaks have happened in countries like Equatorial Guinea, Ghana, the Democratic Republic of the Congo, Kenya, South Africa, Uganda, and Zimbabwe. In 2005, this virus killed 300 people in Angola.

However, for the rest of the world, only two people have died from the virus in the rest of the world, with one of them being in Europe, and the other in the US. These both have been on expeditions to caves in Uganda.

Joshua, 27, was diagnosed with autism at two and a half. He was nonverbal and experienced severe anxiety, while getting a full night's sleep remained a struggle for years.

An experimental drug called L1-79, touted as ‘Ozempic Of Autism' has reportedly brought significant improvements in his condition, according to the Daily Mail, raising interest in its potential to address core features of autism spectrum disorder (ASD).

How Did The Drug L1-79 Help Joshua?

Developed by Yamo Pharmaceuticals, L1-79 is an oral drug designed to target core symptoms of autism.

Joshua’s psychiatrist of eight years, Dr. Eric Bartky, an autism specialist involved in the US FDA trial of L1-79, asked his parents Linda and Jim Turteltaub to consider trying the drug.

The decision involved uncertainty. Taking part in the trial required Joshua to stop all his other medications, and the potential side effects of the new treatment were not fully known. Despite these concerns, his parents decided in 2015 to give it a try.

“We just wanted something to address the issues, to try and get him better so that he can at least communicate with us,” Linda said.

According to the report, Joshua showed his first notable improvement within a week of beginning treatment.

Also read: Autism Care Begins Early: Why the First 1,000 Days Matter Most, Says AIIMS Expert

How Does L1-79 Work?

Yamo Pharmaceuticals describes L1-79 as a selective inhibitor of tyrosine hydroxylase, an enzyme involved in the production of dopamine and norepinephrine.

The drug is intended to lower the production of these chemical messengers in an effort to regulate pathways that may contribute to sensory overload and social withdrawal in people with autism.

Dr. Bartky said the drug differs from existing approaches because it aims to address core features of autism, including social interaction and communication.

“What makes L1-79 different is that L1-79 treats the core symptoms of autism, things like socialization and communications, things that go along with that like eye contact, reciprocal conversation, nonverbal communication, such as reading social nuance. These are things that are extremely important for a person's emotional growth and functioning in society.”

The response to treatment has varied among Dr. Bartky's patients, reflecting the wide range of symptoms associated with ASD.

What Is The Status Of L1-79 Clinical Trials?

Read More: Stem Cell Therapy For Autism: What India’s New Advisory Means For Patients

There is currently no single medication that treats all the core features of autism spectrum disorder. Several medications are prescribed to manage particular behavioral patterns and associated conditions.

L1-79 is being investigated as a potential treatment that could address autism's underlying neurological features. The Daily Mail reported that 116 patients had participated in L1-79's three clinical trials.

The drug has received Fast Track designation from the US Food and Drug Administration (FDA). This program is intended to facilitate the development and review of treatments for serious conditions that address unmet medical needs.

Although the designation does not shorten the clinical trial process, it can make a drug eligible for priority review. Under this pathway, the FDA aims to complete its review within six months, compared with the standard 10-month timeline.

Are There Any Safety Concerns?

Dr. Bartky also pointed to what he described as L1-79's safety profile.

Some existing medications can cause serious side effects, including dyskinesia, which involves involuntary movements that can sometimes be permanent; metabolic syndrome, a group of conditions associated with increased risks of heart disease, stroke and type 2 diabetes; and hypertension. Dr. Bartky said L1-79 had “not had one single serious side effect.”

Are you among those who ditch plastic straws in favor of paper ones? A new South Korean study suggests that switching to paper may not be as environmentally beneficial as it seems.

Commissioned by South Korea's Ministry of Climate, Energy and Environment, the study found that paper straws had 6.33 times the carcinogenic impact of conventional plastic straws. They also had 2.04 times the impact on environmental acidification, which can make soil and water more acidic and potentially harm plants, animals and ecosystems.

What Did The Study Find?

Researchers compared the environmental impacts of conventional plastic straws made from polypropylene (PP), paper straws, biodegradable plastic straws and non-biodegradable bio-based polyethylene (bio-PE) straws.

The assessment, conducted from May last year to April this year, examined four types of straws across 16 environmental impact categories.

Traditional plastic straws had a lower environmental footprint in 10 of the 16 categories, including climate change, air pollution and human toxicity. Paper straws performed worse in categories including carcinogenic impact and environmental acidification.

Meanwhile, bio-PE straws had the highest environmental impact in 10 categories, including ozone depletion, environmental acidification and smog formation.

The findings highlight how the environmental footprint of everyday products can vary depending on the materials used to make them and how they are manufactured and disposed of.

Also read: Can Panty Liners Pose A Cancer Risk? What Science Says

How Was The Environmental Impact Assessed?

Researchers assessed each type of straw across its entire life cycle, from raw material production and manufacturing to disposal.

The analysis assumed that nearly 74% of discarded straws would be incinerated, while the remaining 26% would end up in landfills, The Korean Herald reported.

The results showed that conventional plastic straws performed better than the alternatives in several environmental categories. However, this does not mean they are the most environmentally friendly option in every respect.

Why Are Paper Straws Difficult To Recycle?

Despite being promoted as recyclable alternatives to plastic, paper straws can be difficult to recycle in practice.

Their small size makes them harder for recycling facilities to separate, while coatings and adhesives used in their manufacture can complicate the recycling process.

Paper straws have become commonplace in bars and fast-food outlets as the hospitality industry has moved away from plastic amid consumer concerns about plastic pollution. Although paper generally breaks down more readily than conventional plastic, its overall environmental impact depends on several factors, including production and disposal.

Paper Straws May Contain More 'Forever Chemicals'

Read More: 485 'Inactive' Chemicals In US Pesticide Products Linked To Breast Cancer

A previous study by researchers at the University of Antwerp in Belgium found that paper straws contained per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, more frequently than plastic straws.

These chemicals can persist in the environment for decades, contaminate water supplies and are associated with several health concerns. However, detecting PFAS in a product does not, by itself, establish the level of exposure or the risk to human health from using it.

Trump Administration Moves To Phase Out Paper Straws

In March 2025, the Trump administration launched an effort to phase out paper straws in federal government operations, releasing a White House report titled National Strategy to End the Use of Paper Straws.

The report argued that paper straws were more expensive, less effective and potentially more harmful than conventional plastic alternatives.

President Donald Trump described paper straws as a “pulpy, soggy mess” and raised concerns about the presence of PFAS, chemicals associated with cancer and other health problems, The Daily Mail reported.

Avian influenza, or bird flu, is caused by Type A influenza viruses found naturally in wild birds. The virus can spread to poultry and mammals, including dairy cattle. Humans can become infected through contact with infected animals or contaminated environments. While sustained human-to-human transmission of H5N1 has not been established, continued outbreaks and the virus's potential to evolve are raising concerns about the risk of a future pandemic, experts warn.

Early this month, a resident of Yakima County in Washington tested positive for avian influenza after exposure to infected dairy cattle, the Yakima Health District and Washington State Department of Health announced. The resident is isolating at home and has not developed severe illness or required hospitalization.

H5N1 In Humans: What Do We Know?

According to the Pan American Health Organization (PAHO), 1,002 laboratory-confirmed human H5N1 infections and 479 deaths were reported across 25 countries between 2003 and August 7, 2026. In 2026 alone, nine cases, including two deaths, were reported worldwide.

The H5N1 clade 2.3.4.4b circulating among US dairy cattle has been less lethal to humans than some other H5N1 infections. The US has reported at least 72 human cases since the virus spread to dairy cattle, with two deaths. Most patients had contact with infected animals, The Telegraph reportedd.

Symptoms include fever, cough, sore throat, muscle aches and conjunctivitis. Mild infections may resemble COVID-19 or the common cold, potentially leaving cases undetected.

Migrant dairy workers may also avoid voluntary testing over fears of contact with law enforcement.

“If people don’t feel safe coming forward for testing or care, we risk missing early signs of spread, especially in high-risk populations like dairy farm workers,” Dr Krutika Kuppalli, associate professor in the division of infectious diseases at the University of Texas Southwestern, previously told The Telegraph.

H5N1 Detected In Mink On US Farm

H5N1 has been detected in at least six captive mink on a Utah farm, according to the US Department of Agriculture (USDA).

Scientists are monitoring the virus in mammals because some species can support viral replication and transmission. Mink are of particular concern because they are susceptible to respiratory viruses, and crowded farms could create conditions for viruses to spread and evolve.

"It is REALLY dangerous to let bird flu spread unchecked through mammals, especially minks, which have similar susceptibility & respiratory physiology to humans. The virus can adapt to human hosts by adapting to the respiratory tract of minks," virologist Dr Angela Rasmussen said, in a post on X.

"We don't know if H5N1 will ever make that evolutionary leap or not. We know that it could. But I hope we don't find out. A worst-case bird flu pandemic could literally kill hundreds of millions of people & cause agricultural, ecological, & economic collapse," she added.

How H5N1 Spread From Birds To Dairy Cattle

Marc Johnson, a molecular virologist and professor, shared a timeline of H5N1's spread on X. A new variant spread across the US in early 2022, causing substantial bird mortality and spilling over into several mammal species.

In late 2023 or early 2024, the virus began appearing in dairy cattle's mammary tissue. By the time the outbreak was identified, it had spread to herds across the country.

Johnson said bulk milk testing and strict quarantines could have helped contain the outbreak, warning that the virus continues to circulate among cattle.

"Pasteurization kills H5N1," he said, adding no human cases have been linked to drinking pasteurized milk.

Could H5N1 Trigger Another Pandemic?

Scientists are concerned that continued circulation in mammals could allow H5N1 to evolve and become better adapted to mammalian hosts, potentially increasing the risk to humans.

Johnson warned that "continued spread gives the virus more opportunities to evolve". While sustained human-to-human transmission has not been established, a future pandemic remains inevitable.

How Can You Reduce Your Risk?

People who work closely with animals, including agricultural workers, backyard flock owners, hunters and wildlife workers, face a higher risk.

• Avoid touching sick or dead animals, wild birds, bird droppings and potentially contaminated surfaces.
• Use appropriate personal protective equipment (PPE) when handling infected animals and report suspected animal infections.
• Wear disposable gloves when handling harvested birds and practice good hygiene.
• Ask a healthcare provider about seasonal flu vaccination. It does not prevent bird flu but may reduce the risk of simultaneous infection with human and avian influenza viruses.