Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.

What Is The Role Of Preventative HIV Medicines?

Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".

In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.

HIV In Japan

Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.

Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.

What Are The Challenges In Implementation?

The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.

Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.

Better Healthcare Support

Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.

Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.

What Is The Way Ahead?

Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.

However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.

The U.S. Centers for Disease Control and Prevention on Tuesday withdrew its decades-old guidance that all newborns in the country should be vaccinated against hepatitis B at birth. Instead, the decision has now been shifted to parents, who are advised to consult a healthcare provider when deciding whether babies born to hepatitis B-negative mothers should receive the vaccine, including the birth dose.

The change follows a recommendation made by Health Secretary Robert F. Kennedy Jr.’s vaccine advisory panel, marking a significant shift in public health policy. Earlier this month, the panel suggested that the birth dose be limited to newborns whose mothers test positive for hepatitis B or whose infection status is unknown. The CDC approved this recommendation as official policy on Tuesday. Here is what this change means for newborns moving forward:

CDC Ends Guidance That All Newborns Should Get Hepatitis B Vaccine

Under the updated guidance, if parents decide against vaccinating their baby at birth but later believe the shot is necessary, the CDC now advises waiting until the child is at least two months old before administering the first dose. Since 1991, U.S. health authorities have supported universal infant vaccination against hepatitis B, with the first of three doses typically given shortly after birth. CDC recommendations influence health insurance coverage decisions and serve as a key reference point for doctors when determining vaccine schedules.

Public health experts have raised concerns that the shift toward what the CDC calls “individual-based decision-making” may leave more children vulnerable to the virus and could encourage families to skip vaccination without a strong federal directive. Kennedy, who has long opposed vaccines, has already introduced sweeping changes to the country’s vaccination policies.

CDC New Guidance On Hepatitis B Vaccine: What Does This Mean For Newborns?

Rather than advising hepatitis B vaccination for every newborn, the CDC now formally recommends that women who test negative for the virus discuss with their healthcare providers whether their babies should receive the first dose within 24 hours of birth. According to NBC News, the agency is also evaluating another proposal from the advisory panel, which suggests parents consult doctors about testing children for hepatitis B antibodies before deciding on second doses of the vaccine. Typically, the hepatitis B vaccine is administered as a three-dose series during infancy.

This policy shift stands out as one of the clearest departures from established medical consensus reflected in current CDC guidance. During discussions, the advisory committee relied on selective data and misinformation, while overlooking decades of research showing that hepatitis B vaccines are both safe and highly effective when given soon after birth.

“Removing the recommendation for newborns increases the likelihood that case numbers will rise again. This makes America sicker,” Senator Bill Cassidy, R-La., a liver specialist who has treated hepatitis B patients, wrote on X earlier this month. Despite the change, pediatricians are still expected to encourage parents to vaccinate their newborns.

The Department of Health and Human Services has stated that the updated guidance will not change insurance coverage for the vaccine. The shots will also remain available to newborns through the Vaccines for Children Program, which provides vaccines at no cost to uninsured or underinsured families.

Last month, the CDC also revised a webpage that had previously stated clearly that vaccines do not cause autism. The updated language now says studies have not ruled out a link, despite decades of scientific evidence showing no connection between vaccines and autism.

No more scribbling, notes a BBC report from October 1, 2025, where the Punjab and Haryana court tells doctors to fix their handwriting. Now, the National Medical Commission or NMC has issued nationwide order to the doctors to ensure their prescriptions are written in a clear and legible manner.

While jokes around the notoriously bad handwriting of many doctors that only can be read by pharmacist are common in India, but after the High Court's ruling, this joke is taken seriously. The High Court noted that "legible medical prescription is a fundamental right" as it can make a difference between life and death.

Also Read: Delhi Sees Rising Cancer Burden With Sharp Increase in Oral and Lung Cancers; Breast Cancer Remains Most Common

What Are The New NMC Guidelines On Doctor's Handwriting?

Under the new directive, the NMC ordered that doctors must:

• Write prescriptions in clear, legible handwriting, avoiding ambiguity.
• Arbitrary or unclear prescription writing will no longer be acceptable, as it compromises patient safety.
• Subcommittees will be formed in all medical colleges to monitor prescription practices and ensure compliance.
• Medical students will be taught the importance of clear prescription writing, making it a core part of clinical training.

The Background Of NMC Guidelines

The Punjab and Haryana High Court ordered doctors to fix their handwritings while it was looking at a case that involved allegations of rape. While checking a medico-legal report written by a government doctor who examined the woman, the court found it incomprehensible.

Also Read: Delhi Is a Gas Chamber Where Nothing Comes In or Goes Out, Says Expert; Neighboring States Not to Blame for AQI

Justice Jasgurpreet Singh Puri said, "It shook the conscience of this court as not even a word or a letter was legible".

"At a time when technology and computers are easily accessible, it is shocking that government doctors are still writing prescriptions by hand which cannot be read by anybody except perhaps some chemists," said Justice Puri.

Importance Of Clear Prescriptions

The World Health Organization (WHO) identifies medication errors as a major global patient safety challenge, contributing to avoidable injuries and deaths worldwide. Illegible prescriptions are a well-recognised cause of such errors.

A clear and readable prescription also:

Prevents misinterpretation

Poor handwriting leads to misinterpretation of the intended drug name, dosage, or instructions. Many drugs have names that look or sound alike, making clarity critical.

Ensures the right dosage

Unclear instructions when it comes to dosing result in giving out doses that are ten or one hundred times the correct amount, leading to toxicity or therapeutic failure.

Empowers patient understanding

When the patients are able to clearly read and understand the prescriptions and medication labels, they are more likely to take their medications correctly, reducing the margin for errors.

Reduces healthcare costs

Medication errors resulting from unclear prescriptions lead to increased hospital admissions, prolonged lengths of stay, and additional costs, placing a significant burden on the patient and the healthcare system.

Oral cancer cases recorded the sharpest in Delhi in 2025, as per the Union Health Ministry data presented in the Parliament. While there is no definitive explanation provided by the report by the Union Health Ministry, previous reports show that widespread use of tobacco has increased, and accounted for about 30% of all oral cancer cases in India alone.

As per the report shared by the Union Health Ministry, a 5.1% increase was scene in the reported increase of oral cancer, while lung cancer rose by 4.9% between the period 2023 and 2025.

Also Read: ‘Fix Your Handwriting’: Indian Doctors Told to Write Clear, Legible Prescriptions Under New Rules

The data showed that lung cancer increased among women, and it rose to 6.5%. In numbers, this would make 686 cases in 2025, which is up from the 644 cases recorded in 2024, and 604 in 2023. Among men, oral cancer had the highest growth, with a 5.8% increase. This led to 2,717 cases in 2025, compared to 2,569 cases in 2024 and 2,429 cases in 2023.

However, breast cancer remained the most prevalent cancer in the city. Data from the National Cancer Registry Programme indicate a steady rise in reported breast cancer cases, increasing from 3,198 in 2023 to 3,260 in 2024 and 3,321 in 2025. Oral cancer ranked as the second most common cancer overall, with combined cases among men and women reaching 3,208 in 2025.

A closer look at the data shows that oral cancer continued to rise in the city over the past three years. In 2023, Delhi reported 2,901 cases, including 2,429 among men and 472 among women. The number rose to 3,051 cases in 2024, with 2,569 cases in men and 482 in women. Among women, cases increased slightly further to 491 in 2025.

The International Journal of Research in Medical Sciences provide the tobacco use, betel quid chewing has seen a rising trend in India. Tobacco use includes chewing gutka and khaini in rural areas as well as smoking cigarettes in urban area, which continues to be the nation's leading preventable cause of cancer.

Cervical Cancer Shows a Decline

Cervical cancer followed a different pattern. Cases among women fell from 741 in 2023 to 716 in 2024, and then to 692 in 2025. This reflects a year-on-year decline of around 3.4 percent over both periods.

Rising Trends in Other Cancers Among Men

Among men, oral cancer showed the sharpest increase. Lung cancer cases also rose, climbing from 1,668 in 2023 to 1,814 in 2025. Prostate cancer followed a similar upward trend, with reported cases increasing from 1,168 in 2023 to 1,301 in 2025.

Delhi’s High Cancer Incidence Rate

The health ministry has pointed to Delhi’s relatively high Age-Adjusted Incidence Rate of cancer. Between 2015 and 2019, the AAIR stood at 146.7 per one lakh population among men and 132.5 among women. These figures are higher than those reported in cities such as Mumbai, Kolkata, Pune and Ahmedabad. The AAIR allows cancer rates to be compared fairly across regions with different age profiles.

Treatment Burden Extends Beyond Delhi

It is also important to note that Delhi attracts a large number of cancer patients from across north India and other parts of the country. Major tertiary care centres, including AIIMS and the Rajiv Gandhi Cancer Institute and Research Centre, contribute to a higher treatment load in the city.