Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.

What Is The Role Of Preventative HIV Medicines?

Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".

In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.

HIV In Japan

Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.

Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.

What Are The Challenges In Implementation?

The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.

Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.

Better Healthcare Support

Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.

Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.

What Is The Way Ahead?

Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.

However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.

Reducing sugar intake during pregnancy and the first two years of a child’s life could have life-changing benefits for brain health, particularly in lowering the risk of Alzheimer’s disease.

According to a new study, limiting sugar intake could reduce the risk Alzheimer’s by more than 45% in the future.

The research, published in npj Aging, found that people exposed to lower sugar intake during the first 1,000 days of life, from conception until age two, had a 46% lower risk of Alzheimer’s disease, a 27% lower risk of dementia, an 11% lower risk of depression, and a 20% lower risk of anxiety in later life.

Researchers analysed health and brain imaging data from more than 60,000 participants in the UK Biobank.

They used Britain’s World War II sugar rationing period as a natural experiment, comparing people born when sugar availability was restricted with those born after rationing ended.

Why The First 1,000 Days Matter?

Scientists say that early life is a critical phase for the brain, metabolism, and immune system. Nutrition during this period can shape long-term health, influencing disease risk of neurodegenerative disease decades later.

“Our findings suggest that limiting sugar intake during the first 1,000 days of life may have long-lasting benefits for brain health,” the researchers noted, adding that the effects appear to persist well into older adulthood.

Dr. Bing Zhang, a geriatric medicine researcher involved in the study, said the results support the idea that nutrition in early life can shape lifelong brain health through metabolic programming during critical stages of development.

The study also found key structural differences in the brain. MRI scans showed that participants who had lower sugar exposure early in life had brains that appeared approximately 0.4 years younger biologically.

Their brains showed greater grey matter volume and fewer signs of white matter damage that is often linked to healthier cognitive ageing.

Also read: Can Your Child’s Diet Shape Future Diabetes Risk? Study Links Ultra-Processed Foods To Early Insulin Responses

Does Sugar Cause Dementia?

The researchers found an association, not proof that sugar directly causes Alzheimer’s or dementia. Since the study is observational, other factors like overall diet, access to healthcare facilities and services, and lifestyle may also have contributed to the findings.

Dr. Sara Rodrigues of Alzheimer’s Research UK, who was not involved in the research, cautioned that while the results are compelling, they do not establish cause and effect. However, they add to the growing evidence that healthy eating throughout life plays an important role in maintaining brain health.

Ultra-Processed Foods Linked To Early Insulin Response

This comes after a recent study suggested that children who who consume higher amounts of ultra-processed foods may already be showing subtle changes in the way their bodies regulate insulin, potentially increasing the risk for type 2 diabetes in the future.

According to a new study published in the journal Nutrients, children who have higher amounts of in ultra-processed foods (UPFs) had reduced insulin sensitivity and higher insulin secretion, even though they did not have diabetes.

Researchers from Texas A&M University–San Antonio, University of Texas Health San Antonio, University of Texas Rio Grande Valley, and Wake Forest University School of Medicine discovered that the metabolic changes linked to diabetes may begin much earlier in life than previously thought.

The Democratic Republic of the Congo’s (DRC) Ebola outbreak has become the second-largest Ebola epidemic ever recorded, overtaking the country’s devastating 2018-2020 outbreak.

The current epidemic has also underscored the growing global concern over the rapid spread of the deadly disease.

Second-Largest Ebola Outbreak In DR Congo

According to the latest official figures released by the DRC health authorities and the European Centre for Disease Prevention and Control (ECDC), the country has reported 3,442 confirmed Ebola cases and 1,521 deaths as of July 29, 2026.

However, more recent updates indicate the outbreak has continued to worsen rapidly, with 3,532 confirmed cases and 1,556 deaths reported by July 31, 2026.

The only Ebola outbreak larger than the current epidemic remains the 2014-2016 West Africa outbreak, which infected more than 28,000 people and resulted in the deaths of over 11,300 lives.

Also read: Milestone In Kala-Azar Treatment: WHO Updates Treatment Guidelines, Recommends Shorter & Safer Regimens

Ebola Outbreak Caused By Rare Bundibugyo Virus

Unlike many previous Ebola outbreaks caused by the Zaire ebolavirus, the ongoing epidemic is caused by the Bundibugyo virus, a rarer species of Ebola virus for which there is currently no approved vaccine or licensed treatment.

The World Health Organization (WHO) said the outbreak remains active with heightened community transmission, particularly in eastern DRC, where insecurity, mistrust, population displacement and limited healthcare access continue to hamper outbreak containment efforts.

WHO Warns

In its latest Disease Outbreak News update, WHO said, “The outbreak remains active, with sustained transmission.”

The UN health agency noted that inside conflict, population displacement, community mistrust and restricted access to affected areas continue to affect contact tracing, surveillance, and containment and treatment activities.

WHO has also stressed that although the global risk remains low, the regional risk is high because of frequent cross-border movement between the DRC and neighbouring countries.

A major challenge in controlling the epidemic is the absence of a licensed vaccine or targeted therapy against the Bundibugyo virus.

According to WHO, while the Ebola vaccine used against the Zaire strain has shown limited experimental cross-protection in animal studies, there is currently inadequate evidence to recommend its use against Bundibugyo virus disease.

Also read: Uganda Declared Ebola-Free As Congo Outbreak Grows To 3,262 Cases, 1,437 Deaths

First Volunteer Receives Experimental Bundibugyo Vaccine

Amid the worsening outbreak, researchers have reached an important milestone in Ebola vaccine development.

The first volunteer has received an experimental vaccine targeting the Bundibugyo strain of Ebola, marking the world's first Phase I clinical trial for this virus, according to the University of Oxford.

The vaccine, ChAdOx1 BDBV, developed in collaboration with Serum Institute of India (SII), is designed specifically to protect against the Bundibugyo strain of Ebola.

It uses the same viral vector platform that powered the Oxford-AstraZeneca COVID-19 vaccine.

The vaccine uses a genetically modified chimpanzee adenovirus (ChAdOx1)—a harmless virus that normally causes the common cold in chimpanzees—as a delivery vehicle.

"We welcome the start of the phase 1 clinical trial of an investigational vaccine against Ebola Bundibugyo virus disease—an important step to assess the safety and immune responses generated by the vaccine," said WHO Director-General Tedros Adhanom Ghebreyesus on X.

Health authorities, supported by WHO, Africa CDC and international partners, continue to strengthen surveillance, laboratory testing, infection prevention, community engagement and patient care.

The growing popularity of GLP-1 weight loss drugs like Ozempic, Wegovy and Mounjaro has brought another side effect into focus.

After the widely discussed 'Ozempic Face,' dermatologists are now warning about 'Ozempic Hair,' a term used to describe excessive hair shedding that can occur after rapid and weight loss.

Experts say the condition is not caused by the medication directly damaging hair follicles. Instead, it is largely linked to rapid weight loss, nutritional deficiencies, and the body's metabolic response to sudden calorie restriction.

Why Are GLP-1 Users Facing Excessive Hair Loss?

According to Dr. Gaurav Garg, Senior Dermatologist, Hair Transplant Surgeon, Dermato-Surgeon and Medical Director at Dermalife Skin and Hair Clinic, New Delhi, cases have become increasingly common in dermatology clinics.

"We are seeing a significant rise in patients complaining of excessive hair shedding after taking GLP-1 weight loss medications. Around 40% of the weight loss drug users visiting our clinics are experiencing mild to significant hair loss, with many noticing hair falling out in large clumps while washing or combing. In most cases, the medication itself is not directly damaging the hair. The problem is rapid weight loss, nutritional deficiencies and the metabolic shock experienced by the body," Dr. Garg said.

He added that the increasing use of these medications without proper medical supervision is further contributing to the problem.

"Ozempic isn't the enemy of your hair; malnutrition and metabolic shock are. By ensuring gradual weight loss and proper nutritional support under expert guidance, many of these problems can be prevented," he said.

Also read: UK Woman Spends £4,000 On Wegovy, Mounjaro, But Loses Less Than 14 Pounds In 15 Months

What Is 'Ozempic Hair'?

'Ozempic Hair' is not a medical diagnosis but a popular term for telogen effluvium, a temporary phase of hair loss due to stress. Rapid weight loss acts as a physical stressor, causing a larger number of hair follicles to enter the resting phase prematurely.

Hair shedding usually becomes noticeable three to four months after a user starts taking GLP-1 drugs. Reduced appetite during treatment may also result in deficiencies of all the nutrients that are important for hair growth. For example, protein, iron, zinc and biotin.

Also read: GLP-1 Microdosing: People Are Experimenting With Weight Loss Drugs & What Do Experts Have To Say About It?

Experts Warn Against Self-Medication

Dr. Garg cautioned that weight loss injections are increasingly being used for cosmetic purposes rather than for legitimate medical conditions.

"One of the biggest concerns today is that these weight loss injections are increasingly being viewed as quick-fix cosmetic solutions rather than prescription medicines meant for specific medical conditions. Many people begin taking them after watching social media content or on the advice of friends, without understanding the nutritional consequences. Hair shedding in most cases is temporary, but prevention is always better than treatment. These medications should never be used casually or without expert supervision," he said.

He stressed that people undergoing medical weight loss should receive appropriate dietary counselling, consume adequate protein, and undergo regular monitoring to reduce nutritional complications.

Echoing these concerns, Dr. Ramanjeet Singh, Director, Department of Dermatology, Medanta Hospital, said the trend reflects the risks of unsupervised use of GLP-1 medications.

"The emerging trend of 'Ozempic Hair' highlights the risks associated not only with rapid weight loss but also with the indiscriminate use of these medications without proper medical evaluation. We are increasingly seeing individuals obtaining weight loss drugs without specialist consultation or using them beyond recommended doses in pursuit of faster results. Hair shedding in such cases usually represents telogen effluvium triggered by rapid metabolic changes and nutritional deficiencies rather than permanent damage to the hair follicles," Dr. Singh said.

He added that the condition is generally reversible with timely intervention, balanced nutrition and medically supervised weight management.

Dermatologists advise people considering prescription weight loss medications to undergo a medical evaluation before starting treatment.

Maintaining adequate protein intake, avoiding crash diets, correcting iron and vitamin deficiencies where necessary, and seeking early dermatological care if excessive hair shedding develops may help reduce the severity and duration of hair loss.