Credits: Canva
Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.
Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".
In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.
Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.
Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.
The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.
Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.
Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.
Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.
Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.
However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.
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Anchovies are tiny fish packed with major health benefits, including high amounts of heart-healthy omega-3 fatty acids (EPA and DHA), lean protein, selenium, niacin, iron and calcium. However, a new study by Andhra University researchers detected microplastics in the edible muscle tissue of anchovies, which form a significant part of the local seafood chain.
The finding, published in the International Journal of Environmental Sciences, raises concerns about potential exposure to microplastics and their possible impact on cognitive function.
While the detection of microplastics in muscle tissue suggests the particles may move beyond the digestive system and potentially expose humans through contaminated seafood, researchers led by Prof C Manjulatha from the Department of Zoology and Gondu Chandrika from the Department of Environmental Sciences stressed the need for further assessment.
Polyamide and PET were among the dominant polymers, pointing to multiple possible sources of contamination, such as synthetic fibers, plastic waste and fishing-related materials.
“These findings emphasize the need for proper disposal and treatment of plastic waste,” the researchers said.
Microplastics are small pieces of plastic, ranging from one nanometer to five millimeters — a fraction of the width of a human hair to about the size of a grain of rice. These have now been detected in human blood, placenta, liver, kidneys and the brain. The study also prompted questions about whether consuming microplastics could have implications for brain health.
In a post on X, Dr Sudhir Kumar, Neurologist at Apollo Hospitals, Hyderabad, explained that although the gastrointestinal tract had the highest load, muscle contamination is what reaches your plate.
“Microplastics tend to accumulate in fat-rich tissue like the brain's myelin sheath, the insulation around neurons. Animal studies show microplastic exposure can trigger oxidative stress and inflammation that disrupt neurotransmission and impair cognition. Human data is still emerging, but the biological plausibility is real,” Dr Sudhir said.
He stressed that it “is a concerning signal, not yet a confirmed verdict”.
“Plastic pollution entering the sea fragments into particles small enough for marine life to absorb; fish take it up through feeding, we take it up by eating the fish. The Vizag study flags exactly this: sewage discharge, urban runoff, and fishing waste feeding this cycle,” the expert said.
The expert advised people to:
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The number of measles cases in Sweden linked to the Urkult Festival has climbed to 21, according to the latest data from the country’s Public Health Agency.
So far, all known cases have been directly linked to the festival, which took place from July 30 to August 2 in Näsåker, in Sollefteå municipality. The majority of those infected are children under 18 years of age, the report said.
Acting State Epidemiologist Erik Sturegård called the rapidly growing number of cases “very unusual” in Sweden, Sweden Herald reported. “It is a disease that can cause very serious illness, even in otherwise healthy children,” Sturegård said.
Also read: US Kindergarten Vaccination Rates Decline, Exemptions Rise as Measles Cases Hit 35-Year High
Sweden’s childhood vaccination program includes the measles vaccine and has 95 percent coverage.
Sturegård said the high vaccination rate means Sweden may not currently be at risk of a major outbreak in the wider population.
However, unvaccinated people, as well as those with underlying conditions that may prevent the vaccine from providing adequate protection, remain at risk of serious illness.
Sturegård noted that most of those infected had not been vaccinated against measles.
“Even though we have 95 percent vaccination coverage in the childhood vaccination program, we have small pockets of people who, for various reasons, have not been reached by the vaccination, or who have chosen not to vaccinate themselves. Then you get a local minor outbreak very easily when measles is so extremely contagious,” Sturegård said.
The cases have been reported from the following regions:
Read More: US Measles Cases Soars; RFK Jr Takes U-Turn, Urges Families to Vaccinate Kids
Measles is highly contagious, making contact tracing time-critical. The Public Health Agency, which has overall responsibility for infectious disease control in Sweden, is in daily contact with the affected regions.
“We have daily meetings with the relevant infection control departments to keep a full overview of what is happening and be able to provide the support needed,” Sturegård said.
Measles is an extremely contagious viral illness that spreads through respiratory droplets when an infected person coughs or sneezes. It can also spread through contact with contaminated surfaces.
The illness typically causes high fever, cough, runny nose, red and watery eyes and a characteristic rash that usually begins on the face and spreads downward across the body.
Other symptoms can include sneezing and small white spots inside the mouth. Measles can cause serious and sometimes fatal complications, including pneumonia and encephalitis, or inflammation of the brain.
READ: Why Are 1.7 Million People Still Vulnerable To Measles Despite Australia’s Elimination Status?
According to the European Centre for Disease Prevention and Control’s latest July 2026 report, nine European countries reported 188 measles cases in June. The highest number of cases was reported by:
In the 12 months through June 30, 2026, 30 EU/EEA Member States reported a total of 2,472 measles cases.
Of these, 717 cases (29.0%) were among children under five years of age, while 1,261 (51.0%) were among people aged 15 years and older.
The highest notification rates were recorded among infants under one year of age, at 62.9 cases per million, followed by children aged 1–4 years, at 30.8 cases per million.
Among cases with known age and vaccination status, 1,602 (74.0%) were unvaccinated, 323 (14.9%) had received one dose of a measles-containing vaccine, and 198 (9.1%) had received two or more doses. Another 41 cases (1.9%) had an unknown number of vaccine doses.
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Children living in London showed faster lung growth after the city introduced restrictions on traffic pollution, according to a new study.
Researchers observed more than 3,400 children aged 6 to 9 in London and Luton for five years, comparing lung development in the two locations. The study was led by researchers from Queen Mary University of London and the University of Oxford and was published in The Lancet Public Health.
London introduced its Ultra Low Emission Zone (ULEZ) in 2019, initially covering central London. The scheme restricts older, more polluting vehicles by charging drivers whose vehicles do not meet emissions standards.
At the beginning of the study, children living in London had poorer lung function than those in Luton. Researchers then tracked the development of their lung as pollution levels changed following the introduction of the ULEZ.
The main measure was FEV1, or forced expiratory volume in one second. It measures how much air a person can forcefully breathe out in one second and is commonly used to assess lung function.
The London children's FEV1 increased by approximately 10 millilitres more per year than that of children in Luton.
By the end of the study, the difference in lung function between the two groups had largely disappeared.
Also read: Christy Knowings Dies At 46 After Asthma Attack: When Can It Turn Fatal?
The improvement in children’s lung development coincided with a greater reduction in exposure to nitrogen dioxide (NO₂), a pollutant strongly associated with vehicle exhaust, particularly from diesel engines.
Researchers found that children's exposure to NO₂ fell more than twice as much in London as in Luton during the study period.
There was also a reduction in the proportion of London children with clinically impaired lung function, from 14% to 9%. In Luton, the proportion fell from 9% to 7%.
Also read: Legionnaires’ Disease Outbreak Investigation In Toronto After 6 Cases Surface: What We Know
Professor Chris Griffiths, senior author of the study, said the speed of the improvement was unexpected. He said, “I was absolutely stunned when I first saw the results.”
He said the “speed of catch up in lung capacity” among London children was particularly striking and suggested that ambitious clean-air measures could help reverse some pollution-related effects on children's lungs.
Lead author Dr Helen Wood, a research fellow at Queen Mary University of London, said, "We already knew that the ULEZ reduced air pollution but now we know that children’s lung health has improved at the same time, which is a really important finding for children and parents living in London."
Children are particularly vulnerable to air pollution because their lungs and respiratory systems are still developing. Long-term exposure to traffic-related pollutants has previously been associated with reduced lung growth.
If children fail to reach their expected lung capacity during development, it may potentially increase their vulnerability to respiratory problems like asthma and COPD (chronic obstructive pulmonary disease), which includes conditions such as emphysema and chronic bronchitis, cardiovascular and metabolic disease, as well as early death.
Reducing exposure to pollution while lungs are still developing could help with growth. The researchers credit improved air quality, associating it with the introduction of ULEZ and better lung development. However, the study cannot prove that ULEZ alone caused improvement.
Other factors may have changed during the five-year period, including travel habits, physical activity, and pollution levels unrelated to the emissions zone. The COVID-19 pandemic also dramatically changed traffic and pollution patterns during part of the study period.
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