Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.

What Is The Role Of Preventative HIV Medicines?

Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".

In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.

HIV In Japan

Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.

Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.

What Are The Challenges In Implementation?

The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.

Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.

Better Healthcare Support

Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.

Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.

What Is The Way Ahead?

Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.

However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.

In a major policy shift, schools and colleges across India are set to introduce comprehensive sex education after the Centre informed the Supreme Court that a nationwide programme on health, safety, relationships and reproductive awareness will soon be rolled out.

The move comes nearly two years after the apex court directed the government to create a structured national framework to improve awareness about sexuality, reproductive health, consent, personal safety and child sexual abuse prevention.

Appearing before a bench of Justices BV Nagarathna and R. Mahadevan, Additional Solicitor General Aishwarya Bhati said the Centre has accepted the recommendations of a 26-member national expert committee. The government plans to implement the curriculum nationwide after the Supreme Court grants its formal approval.

The bench also observed that "sex education is not a Western concept incompatible with Indian societal values," noting that misconceptions have led some states to oppose or ban such programmes despite their public health importance.

What Will Be Taught?

The expert panel has recommended making comprehensive sex education a mandatory part of the school curriculum under NEP 2020. Specially trained teachers would conduct brief 15–20 minute sessions twice a week, with lessons tailored to each age group.

Primary school: Personal hygiene, body awareness, and safe and unsafe touch.

Middle and higher classes: Puberty, hormonal changes, consent, personal boundaries, recognising unsafe situations, seeking help, and reproductive and sexual health.

Experts Call It A Long-Overdue Reform

Health experts lauded the move and reiterated that comprehensive sex education is not about encouraging sexual activity. Instead, it equips children with the knowledge and life skills needed to stay safe, make informed decisions and build healthy relationships.

Speaking to HealthandMe, Dr. Ishwar Gilada, the President Emeritus of the AIDS Society of India (ASI) and a Governing Council member of the International AIDS Society (IAS), called the apex Court's directions a landmark moment after decades of advocating for scientific sex education.

He noted that "early sex education can help prevent child sexual abuse among both girls and boys", and also prevent sexually transmitted diseases (STDs) and HIV.

A key myth about sex education is that it will encourage sexual activity. Busting the myth, Dr. Arti Anand, Senior Consultant, Clinical Psychology, Sir Ganga Ram Hospital, said that "comprehensive sex education is about providing children with the right information at the right age, not encouraging sexual activity".

The experts noted that in the absence of accurate information, children often rely on friends or the internet, where myths and misinformation are common.

Instead, Dr Arti said that a good sex education can:

• Protect children from abuse
• Reduce bullying
• Prevent unhealthy relationships
• Build confidence
• Encourage respect and responsible decision-making
• Help children grow into emotionally healthy, safe and well-informed adults

Studies have proven that comprehensive sexuality education can:

• Reduce risky behaviors
• Lower unintended pregnancies
• Reduce sexually transmitted infections (STIs)
• Help prevent sexual abuse by enabling children to recognise inappropriate behaviour and seek help
• Promote gender equality and mutual respect.

Dr. Amit Prakash Singh, Consultant – Internal Medicine, CK Birla Hospital, Delhi, described comprehensive sex education as an essential life-skills programme that goes beyond reproductive health.

Dr. Singh told HealthandMe that the curriculum will help children understand:

• Puberty
• Consent
• Healthy relationships
• Personal safety
• Gender respect
• Digital safety.

A new study has challenged long-held beliefs about dementia, suggesting that your location may have a significant impact on whether you may or may not develop neurodegenerative disease.

How Was The Study Conducted?

Researchers from the University of Southern California studied health data from more than 214,000 adults across 21 countries.

They found that while many well-known dementia risk factors are universal, their impact can vary significantly depending on a person's country.

The findings suggest that prevention strategies should be customised to local populations rather than relying on a one-size-fits-all approach.

Also read: Healthy Lifestyle Changes Improve Memory, Thinking In Older Adults At Dementia Risk: The Lancet

What Did The Researchers Find?

The researchers discovered that factors like education, obesity, hearing loss, smoking, hypertension, diabetes, depression, and physical inactivity do not contribute equally to dementia risk across the globe.

In some countries, less education emerged proved to be a strong factor, while in others, cardiovascular health or mental health played a larger role.

"Our findings show that dementia prevention isn't one-size-fits-all," the researchers said, emphasizing that risk profiles differ substantially between countries and should inform future public health policies.

Despite these regional differences, the study also identified encouraging similarities. Several modifiable risk factors consistently influenced dementia risk across multiple countries, reinforcing the importance of maintaining healthy lifestyles while allowing governments to prioritize interventions based on local needs.

"Reducing dementia risk requires not only individual action but also supportive systems and policies that shape people's everyday lives," the WHO says.

Also read: Radio Broadcaster Paul Gambaccini Reveals Alzheimer's Disease Diagnosis

The new research strengthens that message by suggesting that a country's healthcare system, education policies, environmental conditions, and socioeconomic circumstances may all influence how dementia develops within its population.

Experts say that these findings could help in designing effective prevention strategies.

For example, countries where hearing loss has a stronger association with dementia may benefit from expanding hearing screening and access to hearing aids, while others might achieve greater impact by improving cardiovascular care, promoting physical activity, or expanding mental health services.

Previous research has estimated that nearly 45% of dementia cases could potentially be delayed or prevented by addressing modifiable risk factors, including controlling blood pressure, managing diabetes, staying physically active, treating hearing loss, avoiding smoking, and maintaining social life.

What Is Dementia?

Dementia is an umbrella term used to describe a significant decline in mental function that is serious enough to affect everyday life.

It commonly impacts memory, thinking, and reasoning skills. Dementia itself is not a single disease, but a collection of symptoms caused by underlying conditions such as Alzheimer’s disease or vascular dementia.

Common signs include:

• Memory problems
• Confusion
• Difficulty finding words
• Changes in mood or behavior
• Trouble completing familiar tasks

The findings come as dementia continues to pose a growing global health challenge. According to the World Health Organization (WHO), dementia affects more than 55 million people worldwide, with nearly 10 million new cases diagnosed each year.

WHO also notes that factors like poverty, limited access to education, healthcare inequality, and employment opportunities can significantly shape an individual's dementia risk.

South Korea is experiencing a sharp rise in sleep disorders across all age groups, but the fastest increase is among its youngest population.

New government data suggests that the number of children under the age of 10 who are undergoing treatment for sleep disorders spiked by 67.5% over the past four years, compared to teenagers and adults.

Alarming Rate Of Sleep Disorder Cases In South Korea’s Children

The surprising trend has raised concerns among pediatricians and sleep experts, who warn that poor sleep habits in early childhood can have permanent effects on physical growth, learning, intelligence, emotional well-being, and mental health.

According to figures released by South Korea's Health Insurance Review and Assessment Service (HIRA), more than 1.34 million people sought treatment for sleep disorders last year, which showed an increase of about 24% compared to 2021

While adults in their 50s, 60s, and 70s still account for the largest share of patients, the fastest growth has been recorded among children less than 10 years of age. Teenagers also experienced a notable increase of more than 32% during the same period.

Also read: Obesity-Driven CKM Syndrome A Growing Public Health Threat, Warns American Heart Association

Why Are Children In South Korea Facing Sleep Disorders?

Excessive Screentime

Health experts say that there are factors that are likely driving the surge. One of the biggest contributors is the widespread and rampant use of smartphones, tablets, and other digital devices before bedtime.

Research states that exposure to blue light suppresses the production of melatonin, the hormone that regulates the body's sleep-wake cycle, making it harder for children to fall asleep.

Increased screen time is also replacing physical activity and playtime outdoors, both of which are essential for healthy nighttime sleep.

Academic Pressure

Academic pressure could also affect children’s sleep. Many children under 10 attend after-school academies called hagwons, spend long hours studying, and have increasingly structured schedules that leave little to no time for adequate rest.

Combined with irregular bedtime and stress, these factors can disrupt normal sleep patterns.

Also read: Chronic Fatigue: More Than Just Lack of Rest

Growing Stress And Anxiety

Experts also point to growing levels of stress and anxiety among children. Family pressures, highly competitive educational environments, and lifestyle changes following the COVID-19 pandemic have all been linked to increasingly poor sleep quality in children.

Mental health problems like anxiety can both contribute to and result from chronic sleep disturbances, creating a cycle that becomes difficult to break.

Insomnia

Insomnia remains the most common sleep disorder diagnosed in South Korea. Previous research has shown that the prevalence of diagnosed sleep disorders in the country nearly doubled between 2011 and 2020, highlighting that the current increase among children is part of a broader national trend.

Poor sleep during childhood could lead to poor attention, memory, learning, emotional regulation, and immune function. Children who consistently sleep too little may also face a higher risk of obesity, depression, and behavioral problems later in life.

Sleep specialists stress that parents should establish consistent bedtime routines, reduce evening screen exposure, encourage regular physical activity, and seek medical evaluation if symptoms like prolonged insomnia, loud snoring, or excessive daytime sleepiness continue.