Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.

What Is The Role Of Preventative HIV Medicines?

Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".

In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.

HIV In Japan

Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.

Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.

What Are The Challenges In Implementation?

The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.

Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.

Better Healthcare Support

Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.

Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.

What Is The Way Ahead?

Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.

However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.

With the launch of generic versions of Ozempic, Wegovy, and Mounjaro, the demand for these weight loss and diabetes medications is skyrocketing in India. Amid the rising demand, there is also a surge of counterfeit jabs—often sold through unregulated online vendors—that can endanger lives.

According to a Reuters report, Indian drug regulators have seized more than 260 suspected counterfeit pens of Eli Lilly's popular obesity and diabetes drug Mounjaro, worth Rs 7 million, ‌from the northern state of Haryana.

The suspected fake pens were recovered from a vehicle on the outskirts of New Delhi, and were kept under improper temperature conditions and appeared in different font sizes compared with the original product, which ⁠raised suspicion of being counterfeit.

The Haryana Food and Drug Control Administration has also arrested two people accused of making and selling the drugs. The primary accused did not have a pharmaceutical license and made the products at a private property, Drug Control Officer Amandeep Chauhan told Reuters. They had ordered peptides used in the drugs and other raw materials from vendors on the Chinese e-commerce platform Alibaba.

The arrested duo also sold the pens on the online marketplace IndiaMART at a 27 per cent discount to the original drug's price, ⁠Chauhan said.

While samples have been sent to government-run laboratories for confirmation, Eli Lilly and Company (India) spokesperson issued a statement welcoming the action against illicit medicines.

Noting that it "takes patient safety extremely seriously", the company stated that it's "actively supporting the investigation and will continue to work with regulatory and law enforcement authorities worldwide to protect patients from the risks of counterfeit products".

Also read: Lehengas, Diets & Now Mounjaro: The New Must-Have For Indian Brides?

Can Fake Ozempic/Mounjaro Pens Turn Dangerous?

The short answer: extremely. The risks go far beyond inefficacy. Some fake jabs contain:

• Insulin – Can dangerously drop blood sugar, leading to seizures or coma.
• Toxic substances – Seized products have been found to contain mercury, cement, and rat poison.
• Bacteria – Due to non-sterile production environments, leading to infections.
• Wrong or mixed medications – Including none of the intended drug at all.

Read More: Can Weight Loss Jabs Surge Divorce Rates? What Experts Are Saying

How To Identify Counterfeit Ozempic/ Mounjaro Pens?

Counterfeit products may have

• spelling errors,
• instruction leaflets not in English,
• unsealed packaging,
• changes in the size, shape, or appearance of medicine

These are indicators that the medicine has not been produced by the original manufacturer or is being illegally sold in the wrong market.

Further, counterfeit drugs are often sold on social media platforms like Instagram, TikTok, or salon backrooms.

Also read: India To Strictly Inspect GLP-1 Drugs To Curb Misuse: Govt Flags Risks Amid Weight-loss Hype

Another major lure of counterfeit Ozempic/Mounjaro is the price tag—black-market versions are often heavily discounted. But remember: this comes at the cost of your health, safety, and potentially, your life.

If you’re unsure about a product, consult your pharmacist or primary care provider. Always ensure that any medication you take has been prescribed by a qualified healthcare provider and obtained from a licensed source.

As Bangladesh grapples with a surge in highly infectious measles cases, neighboring Indian states Meghalaya and Tripura are strengthening preventive measures by ramping up vaccination drives and intensifying surveillance, particularly in border districts, to curb any potential spillover and contain the spread of the disease.

As per media reports, Bangladesh is reporting more than 1,100 suspected infections in a single day. The vaccine-preventable measles has also claimed the lives of 98 children in the country’s one of the worst outbreaks.

Measles: Response In Meghalaya

To strengthen early detection and response in Indo-Bangla border areas, the Meghalaya government conducted an orientation-cum-preparedness meeting last week at the Amlarem Sub-Divisional Office with district administration and health department officials, the Border Security Force, community leaders, and grassroots workers, including ASHAs and Anganwadi workers.

Dr A Khonglah, sub-divisional medical and health officer, Amlarem, informed of a few suspected cases in the state, The Times Of India reported. Khonglah noted there was “no cause for panic”, but stressed that early reporting was critical for timely testing and treatment.

In a notification issued on Monday, Meghalaya’s state health department called for stepping up surveillance in East Khasi Hills District.

“Immediate corrective measures are required in response to ongoing measles outbreaks in Bangladesh and the heightened risk in border districts and blocks. It is imperative to strengthen surveillance, early detection, reporting, and response mechanisms across all sectors in East Khasi Hills District,” the notification said.

The state health department directives include:

• All fever with rash cases (suspected measles) in any age group should be reported immediately to the nearest health facility/ANM/medical officer.
• Ensure close coordination with the health department and World Health Organization (WHO) for timely investigation and response.
• Any child suspected of measles should be strictly restricted from attending school/AWC until complete recovery.
• The measles-suspected child should remain isolated at home with minimal contact to prevent further transmission.
• Sensitize teachers and Anganwadi Workers to identify symptoms of fever with rash.

Tripura: Closely Monitoring Measles Trends

Similarly, Health officials in Tripura are also assessing the prevailing measles and rubella situation, with a focus on vaccination coverage and containment measures.

The officials in a review meeting focused on evaluating infection trends, immunization progress, and the effectiveness of ongoing containment strategies, Northeast Today reported.

Mission Director of the National Health Mission (NHM), Saju Vaheed A on Sunday visited Unakoti district to assess the prevailing measles and rubella situation, with a focus on vaccination coverage and containment measures.

The director reviewed data on vaccination coverage and stressed the need for close monitoring of vulnerable areas.

Also read: Measles Again On The Rise Globally: Is India At Risk?

Measles: Sporadic Outbreaks In India

Since the beginning of the year, India is seeing sporadic outbreaks of measles. Madhya Pradesh's Gwalior reported three outbreaks, and Morena six.

Over January and February 2026, 41 children were diagnosed with measles in Tikari village in Madhya Pradesh.

However, swift action by health authorities with proactive frontline engagement and data-driven rapid response prevented an escalation into large measles outbreaks. These sporadic outbreaks also highlighted the critical importance of measles-rubella (MR) vaccination in protecting children and communities.

Measles in Bangladesh

As per official data, till April 19, Bangladesh recorded 3,443 confirmed measles cases and more than 23,600 suspected infections.

While over 12,000 patients have recovered, the outbreak has resulted in at least 36 confirmed deaths and 181 deaths among suspected cases, MNTV reported.

In response, Bangladesh has vaccinated more than 1.9 million children against measles and rubella in an emergency nationwide campaign.

Health Minister Sardar Md Sakhawat Husain said the situation has begun to stabilize due to early intervention, adding that vaccine supplies remain sufficient to sustain the campaign through June.

What Is Measles?

Measles is a highly contagious virus that spreads through direct contact or through the air when an infected person coughs or sneezes. It is a vaccine-preventable disease that can cause devastating complications, including blindness, pneumonia, encephalitis, and long-term immune dysfunction.

Symptoms typically appear seven to 14 days after exposure and may include:

• high fever,
• cough,
• runny nose,
• red eyes,
• rashes across the body.

To safeguard against measles, individuals should ensure timely vaccination, especially for children.

Maintaining good hygiene, such as frequent handwashing and covering the mouth while coughing or sneezing, helps reduce transmission.

Avoiding close contact with infected individuals and ensuring proper nutrition to boost immunity are also important.

Public awareness and community health programs play a crucial role in prevention.

Weight loss drugs appeal to many for their convenience, but according to some experts, there are a number of noteworthy side effects. From rapid weight gain to sagging skin, several side effects of weight loss drugs have been identified through studies. Now, new research has found that weight loss drugs can cause more muscle loss than clinical expectations. The results, presented at the American College of Physicians Internal Medicine (ACP-IM) meeting in San Francisco, add to existing evidence on the possible adverse effects of GLP-1.

Why does muscle loss occur during weight loss?

When a person loses a considerable amount of weight, they also lose bone mass, muscle mass, and some connective tissue. Experts at the University of North Carolina at Chapel Hill found that no studies directly associate muscle loss with a decline in physical function or strength. However, this clinical gap underscores the need to assess strength and mobility alongside weight loss in patients receiving this therapy. The systematic review identified 36 randomised clinical trials that measured changes in muscle mass and fat among adults using incretin-based obesity medications such as tirzepatide, dulaglutide, or semaglutide.

Each study measured body composition using MRI, CT scans, and bioelectrical impedance analysis. Most of them used DEXA along with other methods to obtain information about lean muscle mass, bone mineral density, and the distribution of body fat. The average age of participants ranged from 20 to 63.7 years. Only four studies included participants aged 60 years and above. None of the studies focused on adults aged 65 years or older.

Average muscle loss on weight loss drugs

Researchers noted a concerning trend: patients’ estimated muscle loss exceeded the 25 per cent threshold. Clinicians had expected a 25 per cent reduction, but not more than that. Experts also found that 68 per cent of people who used the drugs exceeded the 25 per cent benchmark, compared to 50 per cent of those who relied on placebos and lifestyle interventions. None of the studies measured whether the loss of muscle mass was correlated with function or strength loss.

Muscle mass diminishes with age

Despite being a concerning side effect of weight loss drugs, muscle mass is likely to diminish anyway with age. Additionally, the loss is more significant in older adults. Therefore, doctors advise caution when prescribing these drugs to individuals who are more prone to losing muscle function at an advanced age. Ideally, doctors should recommend exercise or physical therapy to patients taking weight loss medications.

The final word

According to experts, weight loss drugs do have a positive side — and that extends beyond obesity treatment. These drugs are also beneficial for diabetes and help reduce the risk of cardiovascular disease. However, it is important to support treatment with the right kind of diet and a proper exercise regimen. Solely depending on the medication can lead to weight gain once it is discontinued. Therefore, for healthy weight loss, it is best to rely on sustainable methods for long-lasting results.