Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.

What Is The Role Of Preventative HIV Medicines?

Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".

In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.

HIV In Japan

Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.

Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.

What Are The Challenges In Implementation?

The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.

Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.

Better Healthcare Support

Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.

Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.

What Is The Way Ahead?

Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.

However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.

The infant formula available on the US market is safe, according to results from the largest and most rigorous study by the Food and Drug Administration (FDA), released today.

Breast milk is widely known as the gold standard and optimal source of nutrition for infants whenever possible. However, as per the CDC, roughly 75 per cent of US infants are dependent on formula for the first six months, and for nearly 40 per cent, it is the exclusive source of nutrition.

The FDA noted that across 300 samples tested, an overwhelming majority had undetectable or very low levels of contaminants, affirming that the US infant formula supply is safe. But the federal agency plans to follow up with additional testing.

“We tested more infant formula than ever before, and the results are clear: most products meet a high safety standard—but even small exposures matter for newborns,” said Health and Human Services Secretary Robert F. Kennedy, Jr., in a statement.

“We will hold manufacturers accountable and give parents honest, transparent data they can trust. Protecting our children’s health is nonnegotiable," he added.

How Was The Study Conducted?

The study included more than 300 infant formula samples representative of products sold at retail across the US and included powders, ready-to-feed liquids, and concentrated liquids.

The samples were rigorously tested and analyzed in FDA laboratories. The results show that the overall levels of contaminants in the infant formula samples tested were low.

However, the FDA noted that it is following up with additional testing as part of the agency’s ongoing robust monitoring and oversight efforts and will take additional action where appropriate.

This includes conducting further testing, including for additional contaminants, continuing to engage with manufacturers on measures to reduce the levels of contaminants to as low as possible, and working to establish action levels for contaminants in infant formula.

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“You can judge a society by how it treats its most vulnerable members. That’s why we’re doing everything in our power to make sure our babies and infants have safe, high-quality formula options that are backed by a resilient supply chain,” said FDA Commissioner Marty Makary.

“The results of this study are encouraging. We will continue to advance formula innovation and safety for the millions of families who depend on it.”

Why Was The Baby Formula Tested?

Formula is made to imitate human breast milk and usually comes from cow milk or soy. According to the present FDA guidelines, every infant formula product is required to have 30 nutrients essential for infants in specific proportions.

Yet, the technology of infants' digestion and nutrition requirements has progressed immensely, leading experts to wonder if the standards are yet sufficient.

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In 2025, the FDA in 2025 began conducting a comprehensive review of infant formula ingredients in the face of increasing parental distrust and industry trends, which indicate that existing rules might not be completely in accordance with recent worldwide research on infant feeding.

Some of the main issues that were considered during the testing include the possibility of iron content, added sugars, and seed oils.

Australia has become the 30th country in the world to eliminate trachoma as a public health problem, announced the World Health Organization (WHO).

Trachoma is the world’s leading infectious cause of blindness, which is preventable but cannot be reversed.

According to the WHO, Australia is among a growing number of countries that have successfully eliminated trachoma, contributing to global progress towards the targets set out in the WHO road map for neglected tropical diseases (NTDs) 2021–2030.

“WHO congratulates Australia on this important achievement,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General.

“This success reflects sustained commitment, strong partnerships, and a focus on reaching populations most affected by health inequities. It brings us closer to a world free from the suffering caused by trachoma," he added.

How Australia Eliminated Trachoma

Australia has achieved the milestone after decades of targeted public health action, particularly in remote Aboriginal and Torres Strait Islander communities, where trachoma persisted despite its earlier disappearance from the rest of the country.

The country established the National Trachoma Management Program in 2006 to boost efforts to fight the disease.

The program implemented the WHO-recommended SAFE strategy:

• Surgery for trichiasis,
• Antibiotics to treat infection,
• Promotion of facial cleanliness,
• Environmental improvement.

Other measures undertaken include

• Regular screening of all communities classified as at-risk of trachoma
• Targeted treatment based on community-level data rather than mass drug administration,
• Prevention activities, including improvements in housing, water, sanitation, and hygiene,
• Strong integration with environmental health programs.

“Elimination of trachoma is a win for the eye health of communities across Australia, particularly those whose lives have been impacted by a disease that is entirely preventable,” said Mark Butler, Minister for Health and Ageing, Australia.

In addition to trachoma, Australia has several endemic NTDs, including Buruli ulcer, leprosy, and scabies.

Validation of elimination of trachoma as a public health problem marks the first time that WHO has confirmed the elimination of an NTD in Australia, which becomes the 63rd country globally and 16th in the Western Pacific Region to have eliminated at least one NTD.

What is Trachoma?

Trachoma is caused by the bacterium Chlamydia trachomatis.

It spreads through close contact with infected individuals, contaminated surfaces, and flies that carry eye and nose discharge.

Environmental risks like poor hygiene, overcrowded households, and inadequate access to water and sanitation facilities can also lead to trachoma.

Repeated infections can lead to scarring of the eyelids, turning eyelashes inward, and ultimately causing blindness if untreated.

As per the WHO, trachoma is responsible for the blindness or visual impairment of about 1.9 million people.

Blindness from trachoma is difficult to reverse.

In areas where trachoma is endemic, active (inflammatory) trachoma is common among preschool-aged children, with the proportion of such children affected sometimes being as high as 90 per cent infection becomes less frequent and shorter in duration with increasing age.

Infection is usually acquired when living in close proximity to others with active disease, and the family is the main setting for transmission.

An individual’s immune system can clear a single episode of infection, but in endemic communities, re-acquisition of the organism occurs frequently.

Trachoma is one of 21 diseases and disease groups that are regarded by the WHO as NTDs.

Together, NTDs affect more than 1 billion people worldwide, primarily in underserved populations with limited access to essential services such as clean water, sanitation, and health care.

The US Centers for Disease Control and Prevention (CDC) has confirmed that the Salmonella outbreak that infected 34 people in 13 states in the country is linked to backyard poultry.

The CDC, in its latest report, noted that backyard poultry, like chickens and ducks, can carry Salmonella germs even if they look healthy and clean. To date, no deaths have been associated with this outbreak, which started on February 26 and lasted up to March 31. However, 13 people have been hospitalized, the federal agency said.

Notably, the CDC analysis revealed that the Salmonella strain may be resistant to the antibiotic fosfomycin. Samples from eight of those patients showed there could be resistance to other antibiotics commonly used in Salmonella infections.

States Reporting Salmonella Outbreak

Michigan has the most cases, with six, followed by Wisconsin and Ohio, each of which has five cases.

Indiana, Kentucky, and Maine each have three cases. Florida, Illinois, Mississippi, New Hampshire, and Tennessee have each confirmed a single case.

Children Under Age 5 More Affected

Forty-one percent of case-patients in this outbreak are under the age of 5 years, and of the 29 people interviewed by investigators, 23 (79%) reported contact with backyard poultry in the days prior to illness.

“Children younger than 5 years old shouldn't handle the birds (including chicks and ducklings) or anything in the area where the birds live and roam. They are more likely to get sick from Salmonella,” the CDC said.

“Of 14 people who reported owning backyard poultry, 13 (93%) bought or obtained poultry since January 1, 2026,” the CDC said. “People reported getting their poultry from various places, including agricultural retail stores.”

The CDC said it will continue to investigate the hatcheries associated with cases.

What Can You Do To Be Safe?

• Always wash your hands for 20 seconds after touching birds, their supplies, or collecting eggs.
• Use a pair of dedicated shoes or boots for your coop and don't wear them inside your house.
• Keep birds and supplies outside the house to prevent spreading germs into your house.
• Children younger than 5 years old shouldn't handle the birds (including chicks and ducklings) or anything in the area where the birds live and roam. They are more likely to get sick from Salmonella.

The CDC also advised businesses to

• Source poultry from hatcheries that take steps to reduce Salmonella contamination.
• Clean and sanitize poultry display areas between shipments of new poultry.
• Provide handwashing stations or hand sanitizers next to poultry display areas and tell customers to wash their hands right after leaving these areas.
• Display poultry out of reach of customers, especially chil­dren, so they cannot easily touch the poultry.

What is Salmonella?

As per the US Food and Drug Administration (FDA), Salmonella is a group of bacteria that can cause gastrointestinal illness and fever called salmonellosis. It can be spread by food handlers who do not wash their hands and/or the surfaces and tools they use between food preparation steps. It can also happen when people consume uncooked and raw food. Salmonella can also spread from animals to people.

The FDA notes that people who have direct contact with certain animals, including poultry and reptiles, can spread the bacteria from the animal to food if hand washing hygiene is not practiced.

Pets, too, could spread the bacteria within the home environment if they eat food contaminated with Salmonella.

Most people infected with Salmonella develop diarrhea, fever, and stomach cramps 6 hours to 6 days after being exposed to the bacteria.

The illness usually lasts 4 to 7 days, and most people recover without treatment.

In some people, the illness may be so severe that the patient is hospitalized.

Children younger than 5, adults 65 and older, and people with weakened immune systems are more likely to have severe illness.