Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.

What Is The Role Of Preventative HIV Medicines?

Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".

In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.

HIV In Japan

Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.

Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.

What Are The Challenges In Implementation?

The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.

Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.

Better Healthcare Support

Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.

Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.

What Is The Way Ahead?

Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.

However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.

Even as India’s flagship health insurance program, Ayushman Bharat–Pradhan Mantri Jan Arogya Yojana (AB PM-JAY), has significantly benefited cancer patients in the country, oncologists and health economists led by the All India Institute of Medical Sciences in a new study have urged for including early cancer detection in its coverage.

AB PM-JAY has, since its launch in 2018, provided crucial financial protection and timely access, reducing financial burden as well as out-of-pocket expenditure for people from poor and vulnerable families suffering from the deadly condition.

However, the study, led by Dr. Abhishek Shankar, an assistant professor in the department of radiation oncology at AIIMS, Delhi, flagged a huge gap between current and required funding.

While AB PM-JAY currently allocates about Rs 7,700 crore per year for cancer, the full five-year Standard of Care (SoC) for cancer, including diagnostics, surgery, targeted drugs, radiotherapy, and follow-up, would require an estimated Rs 33,000 crore annually, revealed the study.

"Better cancer care is not only about spending more, but it is also about spending smarter, especially where early detection and diagnosis and well-designed coverage can prevent both late-stage suffering and catastrophic costs,” said Dr. Shankar.

"This will be a useful strategic shift away from purely increasing budgets toward optimizing care pathways and resource allocation, and also prioritizing early detection," he added.

How AB PM-JAY Has Benefitted Cancer Patients In India

AB PM-JAY, the world’s largest publicly funded health insurance scheme, was launched in 2018 to provide health cover to 55 crore people, corresponding to 12.34 crore poor and vulnerable families.

The government covers up to 5 lakh rupees for treatment such as chemotherapy for breast, ovarian, colorectal, cervical and bone cancers.

As per the latest data from the Health Ministry, India has seen a significant rise in the cancer burden, with the cases rising to 1,569,793 in 2025.

AB PM-JAY has reportedly provided cover for over 68 lakh cancer treatments, worth around Rs 13,000 crore.

What The Study Proposes

1. The study proposed to add the five-year Standard of Care (SoC) for cancer under the AB-PMJAY program. It said that, including diagnosis and treatment:

• will save about Rs 1,500 crore annually
• lead to 1,560 additional survivors per year

2. A five-year "revolving ceiling" of Rs 25 lakh per family, instead of the current Rs 5 lakh annual cap

3. A top-up facility of Rs 10 lakh for high-stage cancers

4. Adding diagnostic coverage and screening support

5. Integrating screening and diagnostics via Health and Wellness Centers under the National Health Mission

"India needs a more balanced framework for evaluating cancer innovations, one that considers not only cost but also the value delivered to patients, society and the health system," said Dr Monika Puri, Public Health Expert.

"Eligible funds for cancer patients should be advanced in the first year itself so that they can complete the intensive treatments and therapies required during the initial phase," said Dr. Sudha Chandrashekhar, Former Executive Director, National Health Authority. She suggested that such support could later be adjusted against entitlement in subsequent years.

Changes in environmental conditions are driving bee sting deaths in India’s northeastern state Assam, warned a scientist at the Indian Council of Medical Research (ICMR).

While rare and preventable, Assam sees about 15–20 deaths every year due to bee envenomation, Dr. Surajit Giri, a snakebite specialist and researcher with the ICMR Zero Snakebite Death Project, was quoted as saying to The Sentinel.

"A massive bee attack can cause instant death. Although Assam does not have accurate statistics, various sources suggest that approximately 15–20 people die every year in the state from such incidents. Importantly, many of these deaths are preventable — if both the public and healthcare providers remain alert and informed," Dr. Giri said.

He added that “changing environmental conditions are pushing bee attack cases” in the state.

Bee Sting Deaths In India: Why The Cases Are Rising?

In February, a 65-year-old umpire died while several players were injured after a swarm of bees attacked them during a cricket match in Uttar Pradesh’s Unnao district.

In 2025, a 62-year-old man in Kolkata’s Durgapur died after being stung by a swarm of bees 890 times. There are several such cases being reported from different parts of the country.

The mounting cases are an ecological warning and is directly linked to environmental stress, Dr. Ankit Upadhyaya, an entomologist at the Chandra Shekhar Azad University of Agriculture and Technology, Kanpur, was quoted as saying to the Hindustan Times.

“Bees are struggling to find food,” he explained, even as "soaring temperatures and erratic rainfall" due to climate change have severely disrupted the “flowering cycle".

Fewer blooms mean nectar shortages, which leave bee colonies "starved, hypersensitive and primed for defense".

In such a scenario, disturbance by pedestrians, by traffic, by construction, and by birds results in aggression.

What Happens In Case Of A Bee Sting? How To Treat

A 2021 study, published in the BMJ Case Reports, explained that a bee sting typically leads to anaphylaxis -- a severe, rapid, and potentially fatal systemic allergic reaction occurring within seconds or minutes of exposure to venom.

Other major complications include

• acute renal (Kidney) failure,
• intravascular coagulation (abnormal blood clotting),
• rhabdomyolysis (rapid skeletal muscle breakdown)
• acute pulmonary oedema (excess fluid buildup in lungs)

Dr. Giri said that a bee sting can turn fatal rapidly because stingers left in the skin continue to inject venom slowly even after the attack ends. He urged the need to sensitize healthcare workers, especially those working in rural areas, about medication for bee sting patients.

Dr. Giri advised that if anyone gets caught in a bee attack:

• Do not jump into a water body as bees will continue to wait above the surface.
• Seek shelter in dense vegetation
• Use fingernails to remove stingers, opposite to their angle of entry.
• Do not squeeze or forcefully pull stingers, as this can inject more venom.
• Wash affected areas gently with soap and water,
• Seek medical care immediately,
• Remain under observation for at least 24 hours.

More than 150 people on board a Princess cruise ship which was touring the Caribbean have become ill with norovirus. The Centers of Disease Control and Prevention (CDC) confirmed the total number to be 153, The CDC noted that 104 of them were passengers, while 49 were crew members. The outbreak was reported on Wednesday.

CDC noted that the Star Princess was a one-week voyage that ended Sunday and passengers and crew members were experiencing symptoms like diarrhea and vomiting.

Princess Cruises noted additional rounds of cleaning and disinfection which were done and ill passengers and crew members were isolated. Staff also consulted with CDC on best practices for eliminating the highly contagious and long-lasting virus - norovirus.

What Is Norovirus?

Also called the bug outbreak, it is caused by the group of viruses that cause severe vomiting and diarrhea. As per the UK Health Security Agency, data for the 2024-25 season in England shows that norovirus laboratory reports are notably higher than the 5-season average.

The data also shows that norovirus typically increases through autumn and into winter, however, this year, an unusual rise has been noticed. The Hospital Norovirus Outbreak Reporting System (HNORS) is showing more outbreaks than average.

Dr Luke Powles, Associate Clinical Director, Health Clinics Bupa Global and UK also explained that this virus is also called the winter vomiting bug and is "one of the most common stomach bugs in the UK. It is highly contagious, so spreads easily". The doctor also notes that while the name suggest 'winter', you can get it any time of the year, though it is most common in colder months.

How Do You Get The Virus?

For most people, having norovirus is unpleasant, but mild and recovery could be made in 1 to 2 days. However, it could be more serious for babies, older people and anyone with any existing health condition.

Anyone can get the virus by accidentally getting particles of virus in your mouth and ingesting it. These particles are from feces or vomit from infected people, or can be transmitted via contaminated food and water. It could also spread by touching unclean surfaces like door handles or cutlery.

It is also the No.1 cause of foodborne illness in the US and first occurred in Norwalk, Ohio, in a school in 1968. This is why the first strain is named after the location and is called the Norwalk virus.

It is the main cause of gastroenteritis. The common symptoms include:

• Nausea
• Projectile vomiting
• Watery diarrhea

Usually it lasts for up to 2 days, though for anyone as mentioned above with an existing health condition, or babies who do not yet have a fully developed immune systems, children and older people may be at more risk. If your symptoms are not relieved in 2 days, or it worsens, or you have a serious illness, it is best to consult your doctor.