Credits: Canva
Japan could become one of the first countries in the world to end the HIV epidemic, says the president of Gilead Sciences Japan, Kennet Brysting. The idea for now could seem a little too ambitious, but it is not entirely unrealistic, given that the availability of medicines that can prevent transmission of HIV. Drugs are not the cure, but control over the spread of virus to the point where the disease is no longer a major public health threat.
Gilead's have two key drugs, Truvada and lenacapavir. These two are playing a crucial role in prevention. Truvada is taken as a daily pill, while lenacapavir requires two injections per year. It can make the virus undetectable in infected individuals and prevent transmission to those who are not infected yet. In trials, lenacapavir showed 100% efficacy in preventing HIV infections. This is why it is describe as "almost a vaccine".
In 2024, Japan also approved Truvada for HIV prevention, but the country has yet to approve lenacapavir for the same. Until now, people in Japan had been importing generic versions of Truvada or purchasing it from clinics that source it from overseas.
Up until now, Japan reported around 25,000 HIV infections, whereas 669 new cases were reported in 2023. For seven consecutive years, the number of new infections remained under 1,000. The downward trend thus shows that the virus has been controlled, however, getting to zero new infections remains the ultimate goal.
Brysting too acknowledged that simply having effective drug is not enough. What is important is to have a proper implementation, access and healthcare support to make sure that these treatments are widely available and effective.
The biggest challenges is testing rates. There is a need to increase testing rates. At this very moment, around 86% people infective with Japan have been tested, but the goal is to increase it up to 95%, with an ideal goal of 100%. Without widespread testing, many infected people may not even know that they are infected and it could transmit the virus.
Another measure issue is the cost of preventative medication. While Japan's health insurance covers treatments for diseases, it does not cover preventative drugs. Those who purchase Truvada for prevention, pay around $470 per month. Some clinics in Tokyo offer generic alternatives too, which is cheaper, but they are not ideal.
Brysting expressed concern that individuals importing medications might not be consulting doctors regularly, which is essential for monitoring HIV status and overall health. Truvada users need to be tested for HIV initially and every three months, along with screenings for other infections and kidney function checks. Without proper medical supervision, there is a risk of misuse and inadequate protection.
Gilead is in discussions with Japanese authorities to improve access and insurance coverage for Truvada, and progress is being made. Japan has shown efficiency in approving critical medicines, as seen during the COVID-19 pandemic when Gilead’s remdesivir was approved in just three days.
Gilead at this moment is not only focused on HIV and hepatitis C, but also expanding into oncology with innovative treatments like CAR-T cell therapy, which strengthens a patient's immune system to fight cancer.
However, Japan’s strict approval processes can slow down drug availability. Phase 3 clinical trials often need to be conducted within the country, and Japan tends to approve medicines much later than other regions. For instance, Truvada was approved for prevention in Japan 12 years after the U.S. and nearly 20 years after its approval for treatment. inancial factors also play a role. The Japanese government adjusts drug prices annually, often reducing them, which can make long-term investment challenging for pharmaceutical companies.
Credits: iStock
Whooping cough deaths are rising in the US, as the country sees a surge in the infection. So far, tens of thousands have been infected, with at least 13 people dead from the bacterial infection this year. While the infection rate is lower than last year it continues to remain above typical pre-pandemic years. The Scientific American reports that the number of deaths have also seen a rise.
Whooping cough or what is scientifically known as the respiratory infection called pertussis is severe, and is characterized by violent cough. It could leave people, especially infants, struggling to breath. While it is rarely fatal, it can have lingering symptoms and thus have earned the name '100-day cough'. Whooping cough is caused by the bacterium Bordetella pertussis, which emits toxins into a person's respiratory tract. This is why early treatment with antibiotics vital to managing the infection. The bacterium is easily spread between people, through direct contact and droplets from mouth or nose. This is what makes it contagious.
According to the Centers for Disease Control and Prevention, the US and its territories recorded 27,871 confirmed cases of whooping cough as of December 20 this year. By the same point last year, cases had reached 41,922, marking a sharp rebound after four pandemic years when annual infections stayed below 10,000.
Also Read: What Is Candida Auris Infection? The Deadly Superbug Spreading In US
As of now, 13 people have died of pertussis this year. As per the report from the Pan American Health Organization, and provision CDC data from last year, 10 deaths were noted in 2024, while three increased in 2025.
Public health experts worry that persistently high whooping cough cases this year, following last year’s surge, may reflect falling vaccination rates. The DTaP vaccine protects infants and young children, while Tdap covers older children and adults. CDC guidelines recommend multiple doses starting at two months, yet only 79 percent of children born in 2021 had received four DTaP doses by age two.
Whooping cough is most dangerous, especially among infants under a year old. Public health experts also recommended that pregnant people must get the Tdap vaccine to transfer the antibodies to newborns. All adults are also advised to get the Tdap vaccine in every 10 years to ensure a continued protection.
Early symptoms that can last for 1 to 2 weeks usually include:
CDC notes that later symptoms could be rapid, violent, and uncontrolled coughing fits. About one to two weeks after early symptoms begin, many people develop intense coughing spells, known as paroxysms. These fits typically last one to six weeks, but in some cases can continue for up to 10 weeks. As the illness progresses, the cough becomes more frequent and severe.
During these episodes, people may produce a high-pitched “whoop” when breathing in, vomit during or after coughing, feel extreme exhaustion, struggle to breathe, have trouble sleeping, or even fracture a rib. Many describe it as the worst cough they have ever experienced.
Credits: iStock
As 2025 ends, more and more people are falling ill. With a surge in flu cases, and mystery disease like adenovirus, thousands of people are already infected. Now, a deadly fungus, also considered a superbug due to its resistance to all types of antibiotics. This is Candida auris.
Also Read: What To Know About The Super Flu Surge In US; 'It Will Likely Get Worse', Say Experts
It is a type of invasive year that can cause deadly infections in people, especially with weakened immune system. As of now, it has infected at least 7,000 people across 27 US states, confirmed the data from the Centers for Disease Control and Prevention (CDC).
The fungus can spread easily in healthcare settings, especially in hospitals and nursing homes. It is also spreading at an "alarming" rate, says CDC. The Hill reported that some strains of the fungus are troublesome because they are resistant to all types of antibiotics that are commonly used to treat fungal infections.
Due to fungus's resistance to antibiotics, it is becoming difficult to contain. As of now, more than half of the states have reported clinical cases of Candida auris in 2025. Another factor that makes it more dangerous is that standard lab tests cannot detect it. In a CDC press release, a CDC epidemiologist Dr Meghan Lyman said, "The rapid rise and geographic spread of cases is concerning and emphasizes the need for continued surveillance, expanded lab capacity, quicker diagnostic tests, and adherence to proven infection prevention and control."
This was first discovered in 2009 in Japan from the ear canal of a patient. Since then, it has spread to many countries, including India, where it was identified as a major public health threat in 2014.
Also Read: New Year's Eve Safety Tips, Fire Departments Across US Share Ways To Welcome 2026 Safely
Healthy people could possibly fight off this infection on their own. However, the population vulnerable could find it more difficult to fight off this deadly fungus. Melissa Nolan, an assistant professor of epidemiology and biostatistics at the University of South Carolina told Nexstar, "If you get infected with this pathogen that’s resistant to any treatment, there’s no treatment we can give you to help combat it. You’re all on your own."
Like the mystery disease, adenovirus, this fungus too can survive on surfaces, said Nolan. “It’s really good at just being, generally speaking, in the environment. So if you have it on a patient’s bed for example, on the railing, and you go to wipe everything down, if in whatever way maybe a couple of pathogens didn’t get cleared, then they’re becoming resistant. And so over time, they can kind of grow and populate in that hospital environment," said Nolan.
Studies show that this superbug is not just limited to the US, but is spreading globally. It has already been found in at least 61 countries and on 6 continents. The study also found that the fungus is becoming more and more drug resistant, all due to its ability to switch from a yeast-like growth to a filament-driven spread. It also contains a cell wall that has proteins and makes it easier to stick on human skin "like glue". This is what enables it to colonize the human cells.
Credits: iStock
New Year's Eve: In just few hours, 2025 will come to an end, and many of us will be partying, most probably drinking and watching fireworks. While all this is fun, but it could turn into a health hazard very soon, if not supervised. However, fire departments from across the states in the US have shared New Year's Eve safety tips. Let's look into it to welcome 2026 safely.
Northwestern Medicine Emergency Medicine Physician Steve R Edelstein says, "The holidays are always a busy time of the year in the Emergency Department. “Conditions outside are precarious, and people are inclined to do things they normally wouldn't do.” In such a scenario, these safety tips could come in handy.
Also Read: NHS Issues Warning for People Taking Lansoprazole for Over Three Months
New Orleans Fire Department (NOFD) noted that New Year's Eve is especially cold, and urged the residents to stay warm and safe. NOFD also warned against the use of alternative heating sources like stovetops and oven and to ensure that all fire and smoke alarms are working. NOFD also will be supplying and installing 10-year lithium battery smoke alarms in the homes of any Orleans Parish resident, free of charge.
The Louisiana State Fire Marshall (LSFM) told people to keep a 200 feet distance from buildings, vehicles and flammable debris. LSFM has also warned against letting children handle fireworks, and avoid using fireworks if impaired by alcohol and drugs.
The Wilmington Fire Department (WFD) says that it is common to celebrate the New Year's Eve with fireworks, and "injuries with fireworks are actually very common", noted Wendy Giannini-King, Community Risk Production Coordinator with WFD. "There are dry leaves and pine straw all over your roofs. And if those fireworks go up and land on your roof, your home is in jeopardy."
Giannini-King recommends people to "Pay attention to the pine straw, have a bucket of water, or some way to extinguish those fireworks after they’re lit off. And then the other thought is a flat surface that’s free of any sort of debris."
Pay attention to the pine straw, have a bucket of water, or some way to extinguish those fireworks after they’re lit off. And then the other thought is a flat surface that’s free of any sort of debris.
Read: Top 4 Simple Tricks That Will Keep You Healthier In 2026
The Village of Key Biscayne Police Department reminded all residents and visitors to celebrate responsibly. The Village of Key Biscayne PD said that their officers will be "out in full force throughout the night to support an enjoyable New Year's Eve that protects everyone in our community".
Drive Safely: Driving under the influence of drugs and alcohol is illegal, if anyone spots an impaired driver, dial 911.
Buckle Up And Obey Traffic Laws: Roadways will be busy, thus allow extra time for travel.
Drink Responsibly: If you choose to drink, do it in moderation and do not provide alcohol to minors.
Firework: Be mindful when operating fireworks and do it safely.
Noise Complaints: Be considerate of your neighbors while celebrating.
Workers at the Dessin Animal Shelter note few things one can do to keep your pets safe during New Year's Eve celebrations. Linda Gambone tells WNEP to keep your pets indoors, take your pets out on walk before it is late. She also recommends turning out some kind of music or TV so they can mask the sounds of it. Ensure to keep an eye on them and keep them safe.
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