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An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
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A US Senate committee has voted to hold former National Institute of Allergy and Infectious Diseases (NIAID) Director Dr. Anthony Fauci in contempt of Congress.
Also read: Lab Leak 'More Likely' Origin of COVID-19, Says Former Biden Adviser Dr. Ashish Jha
The committee voted along party lines to refer Fauci to the US Justice Department, which will decide whether to investigate or pursue contempt charges over his refusal to answer questions after being directed to do so under a congressional subpoena, The Washington Post reported.
The referral does not automatically result in prosecution. It is now up to the Justice Department to determine whether to pursue the case.
Ahead of the vote, Senator Rand Paul said the issue before lawmakers was Fauci's refusal to answer questions—not his views or his handling of the pandemic.
"The chair directed Anthony Fauci to answer. He refused. That is what we are voting on today—not his opinions, not his policies, not anything he said from the podium six years ago," Paul said.
"We are voting on whether a witness who has received the benefit of a federal pardon can be ordered by this committee to answer questions and then defy that order without consequence," he added.
Fauci, 85, said the decision not to answer questions "pained" him but that he was following the advice of his legal counsel. The Fifth Amendment protects individuals from being compelled to incriminate themselves under most circumstances.
Read More: Severe COVID-19 Can Reactivate Dormant Viruses, May Fuel Long COVID Symptoms: Study
As the contempt proceedings moved forward, the Senate committee said it had obtained a backup copy of Fauci's government-issued iPhone, which he used during his tenure as NIAID director, including while leading the Trump administration's response to the COVID-19 pandemic in 2020, The Wall Street Journal reported.
Senator Ron Johnson (R-Wisconsin), chairman of the Senate Homeland Security Permanent Subcommittee on Investigations, said the phone records could provide additional information.
"Hopefully, this device will address many of the questions he refused to answer at last week's hearing."
The hearing is the latest development in the long-running political debate over the origins of the COVID-19 pandemic.
Fauci's legal team noted that he had appeared before congressional committees at least 20 times since the COVID-19 pandemic began and had continued testifying even after retiring in mid-2024. They argued there had been no major COVID-19 developments since then that warranted further testimony.
For years, Fauci has been accused of attempting to conceal the virus's origins and of supporting research at the Wuhan Institute of Virology in China, where some believe the pandemic may have begun through a laboratory leak.
In June, former US Director of National Intelligence Tulsi Gabbard released previously undisclosed communications and documents alleging that Fauci funded research at the Wuhan Institute of Virology that contributed to the pandemic.
Most scientists, however, continue to believe that transmission from an infected animal remains the more likely origin of the virus.
Recently, former White House COVID-19 Response Coordinator Dr. Ashish Jha, in a media interview, said that he believes the COVID-19 pandemic was "more likely" caused by an accidental lab leak than by natural transmission.
"My view on COVID origins isn't new — I've held it since my time at the White House," Jha, who also served as an adviser to former President Joe Biden, wrote on social media platform X.
"Here's the truth: no one in America knows for sure. Anyone telling you they do is selling you something. Based on strong circumstantial evidence I've seen, I think a lab leak is much more likely," he wrote while sharing a clip of his CNN interview.
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TikTok creator Sydney Towle has died at the age of 26 after a three-year battle with cholangiocarcinoma, a rare and aggressive bile duct cancer.
Her family announced her death on social media on Wednesday (Aug. 5), sharing a photo of Towle standing on a mountain peak alongside the message: "Rest in Peace Sydney Elizabeth Towle. An endless ray of sunshine. A daughter, a sister and friend to so many."
"We will always love you so much, Sydney. I am so proud of how hard you fought. I love you," read the caption.
Her older brother, Austin Towle, also shared the tribute on his TikTok account, calling her the "best sister ever."
A day before announcing her death, Austin revealed that Sydney had entered hospice care. The post showed family and friends gathered around her hospital bed.
"Sydney has been moved to hospice and is surrounded by her friends and family. Thank you all for your love and support❤️," he wrote.
Also read: Candida auris: US CDC Reports 3,437 Cases of Deadly Superbug In 27 States
Towle was diagnosed with cholangiocarcinoma at the age of 23, a rare cancer that develops in the bile ducts and is most commonly diagnosed in people over 50.
Her diagnosis followed a lump and a burning sensation in her abdomen in 2023. Initially believed to be a hernia, it was later confirmed to be bile duct cancer.
Following her diagnosis, Towle documented her cancer journey on social media, saying that sharing her experience gave her a "purpose." She built a community of more than one million followers across TikTok and Instagram. Over the course of her illness, she underwent several surgeries, multiple rounds of chemotherapy and immunotherapy, and participated in clinical trials.
In an interview with TODAY.com in November 2024, Towle said five months of chemotherapy and immunotherapy had reduced the size of her tumor, allowing surgeons to remove most of it. However, some cancer remained lining her liver, and doctors planned regular scans to monitor it.
A later MRI revealed a lesion that doubled in size within a month.
She later moved to New York City, where she began working with a new medical team to develop another treatment plan.
Read More: Severe COVID-19 Can Reactivate Dormant Viruses, May Fuel Long COVID Symptoms: Study
In a TikTok video posted on May 17, 2026, Towle revealed that the cancer had spread to her peritoneum, the membrane lining the abdomen and pelvis.
Two days later, she said her oncologist recommended stopping active treatment and transitioning to end-of-life care.
"I said, 'No.' So, we are switching hospitals," Towle said. "We're not at the point where we're giving up."
On June 8, she shared that doctors had found tumors in her lungs. Despite undergoing further surgery, chemotherapy and immunotherapy over the following weeks, her health continued to decline. On July 21, she revealed she had been hospitalized for about a month while waiting to learn whether her treatments were working.
Her social media accounts fell silent soon after. On Aug. 4, her brother announced she had been moved to hospice care. A day later, her family confirmed that she had died, surrounded by loved ones.
Cholangiocarcinoma is a rare cancer that develops in the bile ducts—the slender tubes that carry bile, a digestive fluid, from the liver to the gallbladder and small intestine.
According to the Mayo Clinic, the disease occurs most often in people over the age of 50, although it can develop at any age. It is frequently diagnosed at an advanced stage, making treatment more challenging.
Signs and Symptoms include
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The US has reported 3,437 cases of the drug-resistant fungus Candida auris across 27 states so far this year, according to the latest data from the US Centers for Disease Control and Prevention (CDC).
The figure is about 1,000 fewer than the 4,290 cases reported during the same period last year.
The states reporting the highest number of cases this year are:
The CDC clarified that an increase in reported cases does not necessarily mean the fungus is spreading more rapidly than usual.
"An increasing number of cases does not mean the fungus is transmitting at a more rapid pace than usual," the CDC said.
The agency added that while C. auris cases continue to rise every year, the rate of increase has slowed since 2022.
A CDC analysis published earlier this year, based on 8,033 C. auris samples collected in 2022 and 2023, found:
Candida auris is a type of fungus that can cause serious infections in the human body. It was first identified in 2009.
The CDC said that the drug-resistant fungus continues to pose a major challenge for hospitals, nursing homes, and other healthcare facilities because it is difficult to treat and control.
"Candida auris is an emerging yeast that is frequently resistant to antifungal drugs. C. auris can cause invasive infections associated with high mortality and can colonize patients asymptomatically, which facilitates transmission in health care settings," the CDC said.
"Since it was first reported in the United States in 2016, C. auris has been identified in multiple states, with increasing numbers of cases reported annually. Monitoring national trends in cases identified through clinical testing and screening for colonization is critical to guide infection prevention and control efforts," it added.
Unlike many other infections, Candida auris spreads easily through contaminated medical equipment and direct person-to-person contact. It can also survive for long periods on surfaces and is resistant to many commonly used disinfectants, making outbreaks difficult to contain once the fungus enters a healthcare facility.
Health officials say the steady rise in cases each year points to ongoing transmission in healthcare settings.
Candida auris can infect:
Symptoms vary depending on the site and severity of the infection. Some people may carry the fungus without showing any symptoms.
The CDC noted that most people who develop Candida auris infections are already seriously ill, making it difficult to determine how much the fungus contributes to death compared with their underlying medical conditions.
The fungus is particularly concerning in hospitals and nursing homes because it can survive on surfaces such as doorknobs, counters, and bed rails. Its resistance to multiple antifungal drugs makes infections difficult to treat and eliminate.
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