Credits: Canva
An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
Credit: AI
The Clarence High School in Bengaluru's Richards Town has suspended offline classes temporarily after more than 500 students and 21 staff members reported flu-like symptoms.
According to reports, at least two students have tested positive for H1N1 and one staff member is undergoing treatment at Bangalore Baptist Hospital. The school has been shut down as a precautionary measure as health officials continue to investigate the outbreak.
But before panicking, it is important to understand that 500-plus people falling sick suddenly does not mean there are 500 H1N1 cases. Many of those affected have reported common flu-like symptoms like fever, cough, cold, and body aches, and testing is needed to determine the exact cause.
H1N1 is a subtype of influenza A virus. Patients with H1N1 may present common flu-like symptoms like fever, cough, sore throat, runny or blocked nose, headache, fatigue, and body aches. Some children may also experience gastrointestinal symptoms like vomiting or diarrhoea.
The contagious infection spreads mainly through respiratory droplets that get released when an infected person coughs, sneezes or talks. Crowded spaces like classrooms, school buses, and playgrounds can provide plenty of opportunities for virus transmission.
Children may spread the virus to others before realising they are sick, making it difficult to contain an outbreak.
Also read: H1N1 Flu Rising in India: Why Heart Patients Need to Watch
School settings are particularly prone to respiratory infections as children spend hours together indoors and frequently share objects and touch common surfaces.
In the Bengaluru case, school authorities have also raised concerns about sanitation and waste accumulation around nearby street-food vendors, although this has not been established as the cause of the H1N1 infections.
It is important to understand that not every seasonal flu is caused by H1N1 virus. But isolate your child if he or she child presents the following symptoms:
Please note that not every child with flu will develop a fever. So the absence of fever does not necessarily rule out influenza.
While most children recover without serious complications, some are at greater risk of severe influenza, including very young children and those with conditions like asthma, diabetes, heart disease, or neurological disorders.
Also read: Why Humidity Can Worsen Sinus Symptoms Even Without An Infection?
Certain symptoms should not be dismissed as 'just the flu'. Seek urgent medical attention if a child develops the following symptoms as they can indicate complications like pneumonia, severe dehydration, or other serious effects of influenza.
India's National Centre for Disease Control lists breathlessness, chest pain, drowsiness, falling blood pressure and bluish discolouration among warning signs that warrant urgent medical attention.
Also read: Delhi Sees Nearly 6x Rise In H1N1 Cases: How Is It Different From Other Respiratory Infections?
Not every child with a cough or fever needs an H1N1 test. Testing decisions should be made by a doctor based on the child's symptoms, exposure, and risk factors.
Parents should also avoid administering antibiotics on their own. Remember that H1N1 is a viral infection, so antibiotics is not the right course of treatment.
If a child develops flu-like symptoms, the most important step is not to send them to school. Parents should also:
Credit: Instagram
American model and actress Paris Jackson has opened up about battling depression and dealing with suicide attempts.
In a recent podcast, Jackson revealed that she underwent electroconvulsive therapy (ECT), which she said helped her. While describing the treatment as “painful,” she said it was not a “barbaric” experience.
The 28-year-old said she underwent nine ECT sessions over three weeks, with each session performed under general anesthesia.
Paris Jackson Describes Her ECT Experience
Jackson recalled that she had to replace the metal from her facial piercings with plastic earrings before undergoing the treatment.
“You go in, you get your hospital gown, they knock you out, strap you down, put a bite guard on your mouth [and] electrocute you,” she said while describing the procedure.
“It helps with the neuroplasticity in your brain,” Paris continued. “If I’m not mistaken, it’s still the leading most effective form of depression treatment.”
She said the first couple of sessions were “painful” and that she experienced significant side effects.
“The first time I woke up, and it was the most sharp pain I have ever experienced inside of my head,” she recalled, describing it as soreness after being electrocuted. She also said there were days when she felt “completely not in my head at all.”
Jackson Tried Several Treatments Before ECT
Jackson has previously opened up about her suicide attempts, describing her experience of self-hatred, low self-esteem and feelings that she was not worthy of living.
She has also spoken about engaging in behaviours she felt were inappropriate for her age and trying to grow up too quickly.
Before undergoing ECT, Jackson said she had tried “everything,” including multiple medications and treatment at “five different institutions.”
She also tried CBD, dialectical behavioral therapy (DBT) and eye movement desensitization and reprocessing (EMDR).
She recalled trying different forms of therapy, saying, “I had talked to the empty chair, held the pillow, beat the things with bats while screaming.”
Jackson also underwent transcranial magnetic stimulation (TMS), which she said “helped a little bit with [her] OCD but had no effect on [her] depression.”
Her psychiatrist subsequently brought up ECT as another treatment option.
Jackson now focuses on “holistic health” to make her recovery “sustainable” and sees a behavioral specialist for her OCD.
What Is Electroconvulsive Therapy?
Electroconvulsive therapy (ECT) is a procedure performed under general anesthesia. During the treatment, small electric currents are passed through the brain, intentionally triggering a brief seizure.
According to Mayo Clinic, ECT appears to cause changes in brain chemistry that can quickly improve symptoms of certain mental health conditions.
When May ECT Be Recommended?
ECT is known to rapidly improve severe symptoms of several mental health conditions. It may be used for:
ECT may be considered when a person cannot tolerate medicines or has not found relief from other forms of treatment.
Can ECT Reduce Suicide Risk?
ECT can be used for severe depression accompanied by suicide risk and is known for rapidly improving severe depressive symptoms.
However, ECT is not a universal treatment for suicidal thoughts or behaviour. Its use depends on the individual's condition, medical history and response to other treatments, and it is administered under medical supervision.
ECT Side Effects
Jackson also spoke about amnesia as one of the side effects of ECT.
“Friends visited me, and I don’t remember even seeing them [even though] I have evidence. … I don’t remember the conversations,” she said.
Memory problems are a known side effect of ECT and can affect a person's ability to recall events around the time of treatment.
Credit: iStock
Amid a rise in infectious diseases, particularly measles, a new report from the US Centers for Disease Control and Prevention (CDC) shows that kindergarten vaccination rates declined during the 2025-26 school year.
The report also shows an increase in vaccine exemptions among children.
The CDC report showed that coverage for key childhood vaccines, including measles, mumps and rubella (MMR), diphtheria, tetanus, and pertussis (DTaP), polio and varicella, decreased in more than half of US states.
The CDC, in a statement, said the data showed a 0.1% decline in vaccination coverage among children entering kindergarten.
Further, the data showed that about 280,000 kindergartners attended school without documentation of completing the MMR vaccine series during the 2025-26 school year.
Exemptions from one or more vaccines among US kindergartners increased to 4.2% during the 2025-26 school year, up from 3.6% in the previous school year, the CDC said.
Exemptions rose in 41 states and Washington, D.C. Of these, 24 states reported exemption rates exceeding 5%. The number of kindergartners exempt from one or more vaccines was about 155,000.
The decline in vaccination rates comes amid continued debate over the Donald Trump administration's vaccine policies and controversial changes to childhood vaccination recommendations.
Importantly, the period has seen measles cases reach levels not seen in more than three decades, threatening the US's measles elimination status.
With 38 new outbreaks reported in 2026, there have been 2,566 confirmed measles cases reported in the US as of August 13.
In comparison, a total of 2,289 confirmed measles cases were reported in the US during the full year of 2025. There were 48 outbreaks reported in 2025.
In 2026, nearly 20% of measles cases, or 497 cases, were reported among children under 5 years of age. Of these, 10% were hospitalized due to the highly infectious disease. The highest number of cases was reported among children aged 5 to 19 years, with 1,222 cases, or 48%, followed by adults aged over 20, with 835 cases, or 33%.
In total, 93% of measles cases occurred among people without vaccination, and 7% were hospitalized.
According to public health officials, overall measles vaccination rates should remain above 95% to maintain herd immunity.
"When it comes to vaccination rates, however, anything less than achieving an A+ grade is not good enough. For some diseases like measles, even a small decrease in vaccination rates can lead to more outbreaks of disease because community immunity requires over 95% of susceptible individuals to be immunized," said Dr. Andrew Racine, President of the American Academy of Pediatrics (AAP), in a statement.
He added, "This risk is real: The United States is experiencing a 35-year high for measles cases as federal officials continue to elevate misleading and disproven information about vaccines, inserting unnecessary fear and confusion into families’ decision-making. And we are seeing the results. More than a quarter of a million children started kindergarten last year without protection from the MMR vaccine."
Meanwhile, Trump signed an executive order last week calling for fewer childhood vaccinations by limiting the inoculation schedule to 11 immunizations. The order also recommended splitting the MMR vaccine into three shots taken at separate visits.
© 2024 Bennett, Coleman & Company Limited