Credits: Canva
An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
Harish Rana, the 32-year-old resident from Ghaziabad who had been in vegetative condition for the last 13 years is now waiting for his last few moments. A landmark judgment allowed for passive euthanasia in Rana's case. This means without any active intervention, he will be able to exercise his right to die with dignity. As a result he has been taken off ventilator and other life support systems and shifted to a normal bed. His water tube was removed along with a cap being placed on his feeding tube. Health and Me had previously reported on how AIIMS Delhi has prepared to conduct India's first passive euthanasia.
However, it has been over a week since Rana's food and water supply has been cut off. Reports note that he, along with his parents are facing anxiety after he has been denied food and water for over a week.
On March 23, it marks 10 days since Rana has been shifted to AIIMS. Doctors note that every minute Rana spends in AIIMS is crucial for him, and special care is being taken to ensure he does not suffer during this time. His condition is being monitored and doctors are still administering medications to soothe his brain.
Manish Jain, who represented Rana in Supreme Court and played a key role in securing legal aid for him told NDTV that when the verdict was being announced the entire court was packed. "From the courtroom to the gallery, there was a crowd everywhere, everyone was eagerly waiting to see what the Supreme Court would decide. Both judges became emotional while delivering the verdict; the expression was clearly visible on their faces... I was very disappointed myself. But the family felt that if the verdict came in their favor, it would be a great relief for the patient."
He told the media outlet that when the verdict was being announced the entire court went silent for 10 to 15 minutes and everyone was emotional.
Before the verdict was delivered, both judges met with Harish's family and obtained information from the doctor about every aspect of the case.
Read: Harish Rana Taken Off Ventilator, Shifted To Normal Bed At AIIMS Delhi
Jain describes the verdict saying: "I lost even after winning". He said he had seen Harish himself a several times and knew that he was going through a lot of pain. "13 years is no small thing," he notes. "The way his parents and family cared for him is beyond words. But now the only solace is that the court also understood the situation and gave a verdict that will set an example in the history of the country's judiciary."
It was in 2013 when he suffered severe head injuries after he fell from the fourth floor from his PG accommodation while he was studying at Panjab University. He had been bedridden ever since, and survived on feeding tube. His father filed a petition seeking passive euthanasia under the guidelines Supreme Court had laid down in 2018 under Common Cause judgment. This is the second time the parents have approached the apex court.
In 2024, the court also suggested that Rana could receive home-based care with support from the Uttar Pradesh government. The home-based care includes periodic visits by doctors and physiotherapists. The court suggested that in case home care was not feasible, he could be moved to Noida's district hospital. However, his parents have noted that his condition continued to worsen. Family advocate Rashmi Nandakumar also informed the bench that "nothing seems to be working out".
"He is falling ill quite often and is repeatedly admitted to hospital," she said. The advocate further added that the family only sought passive euthanasia, which is withdrawal of treatment, and not any active intervention.
Justice Pardiwala also read medical reports and observed, "Just look at the condition of the boy. It's pathetic."
Recent court ruling on this case involves a bench comprising Justice JB Pardiwala and Justice KV Viswanathan that allowed the withdrawal of life support for Harish Rana, a resident of Ghaziabad, who has been in a coma and kept alive on tubes for breathing and nutrition after sustaining severe head injuries following a fall from a building in 2013 in Chandigarh.
Credits: Instagram
Perez Hilton thanked doctors and nurses after his care at the Southern Hills Hospital in Las Vegas. He was hospitalized for 21 days after he experienced complications with the medicines he was taking for flu. In a video, he said, "My stupidity landed me in the hospital;". The celebrity blogger explained that he was taking medications on an empty stomach that led to serious health complications.
He posted a video on March 23 on his YouTube channel and said, "It was the worst and best thing that's ever happened to me". The 48-year-old, whose real name is Mario Armando Lavandeira Jr, and goes by Perez Hilton said that he had flu for "about a week" and started to take his medications to get better.
However, the biggest mistake he did was taking those medications on an empty stomach. Though, he shares that he has never had food before any of his medications.
Turns out, the medications were hard on his stomach and intestines. After a week of taking the medications on an empty stomach, he developed an ulcer, a perforation and sepsis that led him to be admitted in a hospital with intense stomach pains.
“The first few days were a lot of pain and constant tests,” Perez recalled. “Because they couldn't find where the perforation was.” He added: “Eventually, after five days, I ended up having laparoscopic surgery. Surgery where they don’t cut you up, but they miraculously make these incisions.”
He aid that surgeons used cameras to "literally flip around all of my organs, trying to find the perforation first. Then after flipping around all of my organs, washing me our 'cause I had so much infection in there. So much infection". He also said that his lungs had to be drained out and that his body "kept falling apart". He was also put on heart medication because his "heart got out of control".
Read: World Tuberculosis Day 2026: Theme, Origin, And Significance
Due to his long hospital stay, he developed another infection and for two weeks he could not eat normal food. “It was such a slow process,” Perez shared. “Two weeks of just sickness and then another week of getting better before I was released. The last week was hell, because I had already been in the hospital two weeks by then.”
Perez is now at home and would continue to receive his medication intravenously through a PICC line in his arm for 10 days. He said it is more effective than oral medications. “When I saw my kiddos—who had visited me—but when we got home we had the biggest, most cathartic group hug. And tears and tears and tears. They were so worried for their dad," he said.
He also said that he learned from his experience of being hospitalized and hopes that his video works as a "cautionary tale" to those who are watching. He said, "I hope this video can be a cautionary tale to some of you. Take medication with food. That's very important. Take medication with food. Don't have it on an empty stomach. Don't end up like me in the hospital for 21 days.”
Credits: Canva
Every year on March 24, World Tuberculosis (TB) Day is observed. According to the World Health Organization (WHO) data, 10.7 to 10.8 million people fell ill with TB, globally in 2023-2024. This has made TB the world's top infectious killers. While many countries have been able to successfully reduce the cases of TB, there has been resurgence of the disease in Indonesia, Myanmar and the Philippines. While in the United States and in high-income European nations, the infection levels remain low, however, the disease has not been fully eradicated.
This is why, this year's theme is 'Yes! We can end TB!' As per the WHO, this is a bold call to action and a message of hope that affirms that it is possible to get back on track and turn the tide on the TB epidemic, even in a challenging global environment. With decisive country leadership, increased domestic and international investment, rapid uptake of new WHO recommendations and innovations, accelerated action, and strong multisectoral collaboration, ending TB is not just aspirational - it is achievable.
The Centers of Disease Control and Prevention (CDC) notes that it was on March 24, 1882, when Dr. Robert Koch announced the discovery of Mycobacterium tuberculosis, the germ that causes tuberculosis (TB). A century later, in 1982, the global health community recognized March 24 as World TB Day.
In 1882, the disease killed one in seven people in the US and Europe, however, Koch's discovery was significant in the elimination of TB disease.
The CDC also notes that TB germs may have been around as long as 3 million years. During ancient times, TB had several names, for instance, it was called:
World TB Day is held annually on March 24 to raise awareness, mobilize funding, reduce stigma, and accelerate global efforts to end the tuberculosis epidemic. This disease kills thousands daily and is thus a critical call for action on prevention and treatment is important.
As per a Singapore Government Agency Website called Communicable Disease Agency or CDA, TB is an infectious airborne disease caused by Mycobacteirum tuberculosis.It primarily affects the lungs but can also affect other parts of your body, such as the brain, lymph nodes, kidneys, bones, and joints.
The disease is transmitted through the air when an infected person coughs or sneezes and usually requires close and prolonged contact with an infectious individuals. It cannot spread through touch or kissing.
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