Credits: Canva
An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
Credits: Canva
Cancer Postcode Lottery will soon be put to an end by the UK Government. Reports say that it will enable the rural population access to cancer specialists and treatments. Before getting into how it will help the rural population and people living in coastal areas to find it easier to see a cancer doctor, let us first understand what postcode lottery means.
The term cancer postcode lottery refers to a situation where a cancer patient’s access to the latest and most effective treatments depends on where they live or which hospital they are treated at, rather than purely on medical need.
Based on the information you shared, senior cancer doctors in England are warning that this is happening because of bureaucratic hurdles within the NHS. Even though cancer care is supposed to be equitable across the country, in practice, not all hospitals can easily offer the same treatments.
Doctors say that some cutting-edge cancer treatments such as advanced radiotherapy techniques and newer immunotherapy drugs require separate funding approvals. Individual cancer centers often have to apply to NHS England for permission and money to use these treatments.
Larger, better-funded hospitals with more administrative resources are often able to navigate this complex system more easily. Smaller or less well-resourced units may struggle, meaning patients treated there may not get access to the same options.
For instance, Stereotactic Ablative Body Radiotherapy (SABR). SABR is a highly precise form of radiotherapy that delivers strong radiation doses directly to small tumors in areas such as the lungs, liver, brain and lymph nodes. Although SABR is a well-established treatment and can be life-saving for certain patients, the Royal College of Radiologists (RCR) says some cancer units still have to apply for special funding to use it. This leads to situations where a patient in one area can receive SABR, while another patient with the same cancer elsewhere cannot.
As per the official website of UK Government, this will allow people "living in rural and coastal communities will find it easier to see a cancer specialist as part of plans to tackle the current postcode lottery."
The website notes that most deprived parts of the country have fewer cancer consultants, which leaves patients waiting longer for essential care. These same areas also face highest economic inactivity, with long waits for diagnosis and treatment keeping people out of work and holding back local economies. This is why the government is now introducing "new training places targeted at trusts with biggest workforce gaps, prioritising rural and coastal areas".
Working with the Royal Colleges, the government will encourage more doctors to train in clinical and medical oncology to increase the number of cancer specialists in underserved areas.
These steps will be outlined in the upcoming National Cancer Plan, which aims to speed up diagnosis and treatment, reduce inequalities, and support the goal of making England a global leader in cancer survival, while building a future-ready NHS.
Credits: Canva
A treatment already popular in the US for skin care, pain relief, and faster healing may soon be known for something far more serious. A new study suggests red light therapy could help protect football players’ brains from chronic inflammation caused by repeated hits to the head.
Experts say the findings are early but promising, especially in the ongoing search for ways to reduce long term brain damage in contact sports.
Chronic traumatic encephalopathy, or CTE, is a degenerative brain disease linked to repeated head injuries. It is commonly found in former football players, boxers, and military personnel exposed to blast injuries. Over time, the condition can cause memory loss, confusion, mood changes, aggression, and eventually problems with movement, speech, swallowing, and breathing. There is currently no cure, and doctors still do not know how to slow its progression.
For now, the only proven way to lower CTE risk is to reduce repeated brain trauma through better helmets, rule changes, and fewer hits to the head. But with more than 100 former NFL players diagnosed with CTE after death and many more suspected cases, experts agree that prevention tools alone are not enough.
Researchers believe chronic inflammation in the brain plays a major role in how CTE develops and worsens over time. If that inflammation can be reduced early, it could potentially limit long term damage.
Red light therapy, also known as photobiomodulation, has already been shown to reduce inflammation in other parts of the body. It works by stimulating energy production inside cells and improving blood flow, which helps tissues repair and recover.
To see whether the therapy could help the brain, researchers at the University of Utah Health studied 26 collegiate football players during a full season. Half received active red light therapy using a light emitting headset and a small device placed inside the nose. The other half used an identical looking device that did not emit light.
Players completed three 20 minute sessions each week over 16 weeks. Brain scans were taken before and after the season.
Read: 21-year-old Billy Vigar Of Chichester City Dies Of Sustaining Brain Injury
The results were striking. MRI scans showed that players in the placebo group experienced a significant increase in brain inflammation by the end of the season. In contrast, those using red light therapy showed little to no increase, with protection seen across most brain regions.
Specialists who reviewed the findings say the results align with what scientists already understand about inflammation and brain injury. Reducing the inflammatory response after repeated impacts could help limit the damage that builds up over time.
Another advantage is that the therapy is non invasive and does not involve medication. Most users report no major side effects, which makes it especially appealing for athletes.
That said, experts caution against buying over the counter red light devices. The therapy requires very specific wavelengths that can penetrate skin and tissue effectively. Many consumer products do not meet those standards.
Researchers stress that more studies are needed to confirm long term safety and effectiveness. A large Department of Defense funded trial is already planned, involving 300 people with persistent concussion or traumatic brain injury symptoms, including veterans and first responders.
If future research continues to show benefits without harm, red light therapy could one day become part of how teams protect athletes’ brains, not just in football, but across many sports.
Credits: Wikimedia Commons
Nicole "Snooki" Polizzi opened up about a cancer scare. Now, 38, the Jersey Shore star, posted on her TikTok an emotional video, where she explained that she has been dealing with abnormal pap smear results. She said that it has been about four year since the precancerous cells were found. Because of that she had to undergo an "uncomfortable" colposcopy and biopsy.
She said that when the results came back, the doctor informed her that her cervix is "Not looking great". The doctor had found cancerous cells on the top of her cervix. She said that she would soon need a cone biopsy under anesthesia for further testing. "I am terrified. It is scary, but we have to get it done because cervical cancer is nothing to joke about."
She said, "But whatever to keep me healthy and safe to be here for my kids that I have now," referring to her three children with her husband Jionni LaValle.
In her TikTok video, she said that she is scared and freaking out. She also said that she hopes to find community on social media with other women who have been through the same.
She also agreed to delaying her routine examination because of fear. "I waited on my appointments because I knew I might not get great results but also because I didn't want to feel the pain. I didn't want to deal with the stress of having to deal with all of this," she said.
Talking about her TikTok video, she said, “Just making this video to spread awareness to make sure you get your pap smears. And if your doctor calls you to do it again, do it, Make sure you are fine and prevent all the bad things that could happen, like cervical cancer." She said she was nervous but also shared that she received a lot of support from her friends and family. "Being a woman is not easy and is definitely a scary thing. I know I am going to be fine. It is just scary."
Read: Oncologist Reveals 5 Subtle Cervical Cancer Signs That You May Miss
Cervical cancer develops in a women's cervix (uterus opening) due to abnormal cell growth, primarily caused by persistent HPV infection, a common infection that's passed through sexual contact.
When exposed to HPV, the body's immune system typically prevents the virus from causing damage however, in a small percentage of people, the virus can survive for years and pave the way for some cervical cells to become cancerous.
Treatment involves surgery, radiation, and chemotherapy, with early detection significantly improving outcomes, though it remains a major cancer in low-income countries. Cervical cancer can also be prevented through vaccination and regular screening (Pap/HPV tests).
Dr Ninad Katdare told News18: "In its early stages, it is often more of a whisper than a shout. As a cancer surgeon who has treated hundreds of women with gynaecological cancers, I can say with confidence that recognizing these subtle cues can lead to earlier diagnosis and significantly better outcomes."
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