Is 'Sticky Gunk' In Your Brain The Reason Behind Alzheimer's Disease?

Updated Mar 20, 2025 | 08:53 AM IST

SummaryThe new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years.
Alzheimer's Disease

Credits: Canva

An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.

One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.

Slowing Down The Symptoms

Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.

How Was The Research Conducted?

The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.

The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.

Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”

The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.

Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.

The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.

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US Humanitarian Worker Tests Positive For Ebola As Congo Outbreak Tops 1,800 Cases

Updated Jul 12, 2026 | 12:15 PM IST

SummaryAmid rising cases and slow containment efforts in Congo, a humanitarian volunteer from the United States recently tested positive for Ebola.
US Humanitarian Worker Tests Positive for Ebola as Congo Outbreak Tops 1,800 Cases

Credit: iStock

A U.S. humanitarian worker in the Democratic Republic of the Congo (DRC) has tested positive for Ebola, raising fresh concerns as the country struggles with one of the worst Ebola outbreaks.

US Humanitarian Worker In DRC Tests Positive For Ebola

On Friday, the U.S. Centers for Disease Control and Prevention (CDC) confirmed, saying it is working closely with the individual's employer, U.S. government health agencies, and Congolese health authorities to prevent further transmission by tracing contacts to identify people who may have been exposed.

According to reports, the infected individual was working for a humanitarian organization in eastern Congo, where the outbreak has continued to spread despite ongoing response efforts.

The CDC has not released details about the patient's identity or condition but emphasized that contact tracing and public health measures are underway.

A spokesperson for the U.S. State Department said it is aware of the case and is assisting the affected American.

The spokesperson said, “A U.S. citizen working for a humanitarian organization in the Democratic Republic of the Congo has tested positive for the Bundibugyo strain of the Ebola virus. The CDC is working with the patient's employing organization, other federal agencies and partners in the Democratic Republic of the Congo to help prevent further transmission and identify high-risk contacts.”

The health regulatory body further said, “The risk of Ebola spreading in the United States remains low.”

Also read: Ebola In DRC Is Still In ‘Expansion Phase’: WHO Doctor Opens About Major Challenges In Containing The Outbreak

Ebola Outbreak In DRC: Latest Updates

The case comes as the Democratic Republic of the Congo faces an escalating Ebola crisis. According to the Africa CDC, the outbreak has now reached 1,830 confirmed cases and 648 deaths, making it the fastest-growing Ebola outbreak ever recorded on the continent. The outbreak was officially declared on May 15, 2026, and has spread across multiple provinces in eastern Congo.

Health officials say this outbreak is particularly concerning because it is caused by the Bundibugyo strain of the Ebola virus, a rare variant for which there is currently no approved vaccine or specific antiviral treatment.

WHO Says Actual Number Of Cases Could Be Higher

The World Health Organization (WHO) has also warned that the official case count may significantly underestimate the true scale of the outbreak.

WHO modeling suggests that actual infections could be two to four times higher than reported because many cases are not being detected.

Nearly 80% of newly identified infections in some of the hardest-hit communities cannot be linked to known Ebola patients, indicating widespread community transmission.

The agency also reported that about 70% of deaths early in the outbreak occurred outside treatment centers, making surveillance and contact tracing even more difficult.

WHO Emergencies Director Chikwe Ihekweazu told Reuters, “Eighty percent of the new patients confirmed are coming outside of known contact lists” in Bunia, the epicenter of the outbreak, highlighting widespread undetected transmission.

He also warned, “The true scale of the outbreak is likely two to four times larger than the official figures suggest.”

The latest case highlights the dangers faced by frontline aid workers and underscores the urgency of strengthening outbreak control measures before the virus spreads further.

With no approved vaccine for the Bundibugyo strain and transmission continuing in several provinces, global health officials say rapid detection, isolation, and international cooperation remain essential to bringing the outbreak under control.

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England Confirms Third Measles Death: NHS Launches Catch-Up MMRV Vaccination Drive

Updated Jul 10, 2026 | 09:22 PM IST

Summary The Measles, Mumps, Rubella and Varicella vaccine contains weakened forms of the measles, mumps, rubella, and chickenpox viruses, which stimulate immunity without causing disease.
England Confirms Third Measles Death: NHS Launches Catch-Up MMRV Vaccination Drive

Credit: iStock

Health officials in England have confirmed that an adult with an underlying immunological condition has died from measles, marking the third measles-related death this year after two children died in June.

According to the latest figures from the UK Health Security Agency (UKHSA), England has recorded 883 confirmed measles cases between the start of the year and July 6. More than half of the cases have been reported in London, with most infections occurring in children aged 10 years and under.

All regions of England, including London (52 per cent), the West Midlands 17 per cent, and the North West 10 per cent, have now reported measles cases.

The UK was declared measles-free in 2017 but lost that status in 2019 after vaccination rates declined and outbreaks resumed.

In January, the World Health Organization (WHO) confirmed that the UK was no longer considered to have eliminated measles, citing stagnant vaccination coverage and rising case numbers.

NHS Launches Catch-Up Vaccination Drive

Also read: Experts Say US Cyclospora Parasite Outbreak Is Unusual: How To Clean Fresh Produce

In response to the surge in infections, NHS leaders have launched a nationwide catch-up campaign targeting children aged two to 11 years who have missed one or both doses of the measles, mumps and rubella (MMR) vaccine.

The program will contact around one million families whose children are not fully vaccinated.

  • GPs will contact parents of children under six.
  • Families with children aged six to 11 will be contacted through the NHS App, text message, email or letter.

Current figures show that 84.1% of five-year-olds in England had received both doses of the MMR vaccine during the first three months of the year—well below the 95% coverage recommended to prevent outbreaks.

"We urge all parents to ensure their children are up to date with their MMR or MMRV vaccines, giving them the best and safest protection against measles," said Dr Vanessa Saliba, consultant epidemiologist at UKHSA.

"Anyone who has missed their measles vaccines can catch up through their GP practice, whatever their age. Getting vaccinated also helps protect babies who are too young to be vaccinated and people who cannot receive the vaccine because of certain health conditions," Dr Saliba added.

What Is Measles?

Read More: Crusted Scabies Outbreak: UK Reports Rare Highly Contagious Skin Disease

Measles (rubeola) is one of the world's most contagious viral infections. It spreads through respiratory droplets released when an infected person coughs or sneezes and can also spread by touching contaminated surfaces before touching the eyes, nose, or mouth.

Symptoms usually develop 7 to 14 days after exposure and include:

  • High fever
  • Cough
  • Runny nose
  • Red, watery eyes
  • Small white spots inside the mouth (Koplik spots)
  • A red rash that typically starts on the face before spreading across the body

While many people recover fully, measles can cause serious complications, including pneumonia, encephalitis (brain inflammation), hearing loss, and, in rare cases, death.

All About the MMRV Vaccine

The MMRV is a safe, live-attenuated immunizations that protect against severe viral infections. The shot combines Measles, Mumps, and Rubella, and also adds protection against Varicella (chickenpox).

According to the UKHSA, children receive:

  • First dose: At 12 months, alongside MenB and pneumococcal (PCV) vaccines.
  • Second dose: At 18 months, alongside the fourth 6-in-1 vaccine.

Children who miss these doses can receive a catch-up vaccination at their 3-year and 4-month appointment. The MMRV vaccine contains weakened forms of the measles, mumps, rubella, and chickenpox viruses, which stimulate immunity without causing disease.

Two MMRV vaccines are available:

  • ProQuad (contains porcine gelatine)
  • Priorix Tetra (does not contain porcine gelatine).

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​Experts Say US Cyclospora Parasite Outbreak Is Unusual: How To Clean Fresh Produce

Updated Jul 10, 2026 | 05:25 PM IST

Summary​Experts also warned that the reported infections may represent only the "tip of the iceberg," with additional cases expected in the coming weeks, because the infection takes long to manifest.
​Experts Say US Cyclospora Parasite Outbreak Is Unusual: How To Clean Fresh Produce

Credit: iStock

An outbreak of Cyclospora, a microscopic parasite that causes prolonged watery diarrhea, has sickened more than 1,400 people across the United States, with infectious disease experts describing the surge in cases as "definitely abnormal."

While the US Centers for Disease Control and Prevention (CDC) is still investigating the source, officials believe the outbreak is likely linked to multiple sources of contamination rather than a single food product.

Health officials in Michigan have reported 1,251 Cyclospora infections, a dramatic increase from around 170 cases recorded on June 30. The state typically reports only about 50 cases annually.

Ohio has confirmed nearly 200 cases, while New York, Illinois, Indiana, North Carolina, and Texas have also reported an increase in infections. More than 40 people have been hospitalized.

Dr. Thomas Moore, an infectious disease specialist and clinical professor of medicine at the University of Kansas School of Medicine-Wichita, described the spike as "definitely abnormal" and concerning, according to The New York Times.

Keith R. Schneider, professor of food safety at the University of Florida, noted that Cyclospora infections usually increase between May and August in the United States. However, he said the current surge—particularly in Michigan—is far beyond what is normally expected.

"Something is going on right now in that area," Schneider told The New York Times.

Experts also warned that the reported infections may represent only the "tip of the iceberg," with additional cases expected in the coming weeks, because the infection takes long to manifest.

Also read: Crusted Scabies Outbreak: UK Reports Rare Highly Contagious Skin Disease

What Is Cyclospora And How Does It Spread?

Cyclospora is a microscopic parasite that infects people after they consume food or water contaminated with human feces containing the parasite's eggs (oocysts).

Unlike many foodborne bacteria, Cyclospora infections often takes two days to two weeks or more to cause illness after exposure, making it difficult for investigators to identify the original source.

Although the illness is usually not life-threatening, it can cause prolonged diarrhea, stomach cramps, nausea, fatigue, bloating, and weight loss.

Fresh produce is the most common source of infection, though contaminated water can also spread the parasite. Health officials have not advised people to avoid fresh produce, as investigators have not yet identified the exact food responsible for the current outbreak.

Yet, previous US Cyclospora outbreaks have frequently been linked to imported fresh produce, including:

  • Basil
  • Cilantro
  • Mesclun lettuce
  • Raspberries
  • Snow peas

Read More: Bryan Johnson's Autoimmune Gastritis: US Doctor Explains the Hidden Signs of Autoimmune Disease

Handwashing Matters More Than Hand Sanitizer

Experts emphasize that proper handwashing with soap and water remains one of the most effective ways to reduce the risk of infection.

Alcohol-based hand sanitizers do not kill Cyclospora, making soap and water essential after using the bathroom and before preparing or eating food.

"This type of parasite doesn't easily go away with alcohol-based hand sanitizer. So, good old handwashing is really key here," ABC News medical correspondent Dr. Darien Sutton said.

How To Clean Fresh Produce Safely

While washing produce cannot eliminate all risk, experts say it can reduce contamination. They advised washing fruits and vegetables thoroughly under clean running water, and washing hands before and after handling fresh produce.

According to the Michigan Department of Health and Human Services, cooking produce whenever possible during an active outbreak is crucial, as heating food to at least 158°F (70°C) kills Cyclospora.

For specific produce, it suggested:

  • Cilantro and basil: Separate the leaves and rinse each thoroughly under running water.
  • Green onions: Trim off the roots, remove the outer layer, and rinse well.
  • Snow peas: Rub the surface gently while washing under running water.
  • Raspberries: Because of their delicate, uneven surface, raspberries are difficult to clean thoroughly. Cooking them in pies or jams is safer. Freezing may reduce the number of parasites but is unlikely to eliminate them completely.
  • Leafy greens: If possible, choose whole heads of lettuce instead of bagged salad mixes. Discard the outer leaves and wash the remaining leaves under running water before eating.

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