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An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
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AIIMS New Delhi launched free cervical cancer screening through January as a public interest drive. In India, in every 8 minutes, 1 woman loses her life to cervical cancer, however, doctors say that it is highly preventable. Thus, as part of the Cervical Cancer Awareness Month, Preventative Oncology at the Institute of Rotary Cancer Hospital and the National Cancer Institute, in collaboration with the College of Nursing, is offering the WHO-recommended HPV testing, follow-up care, and vaccination.
Dr Pallavi Shukla, Associate Professor of Preventative Oncology, AIIMS, who is coordinating the programme said, "This is one cancer which is absolutely preventable. Women should not neglect their health at any age, we must make earnest efforts to eliminate cervical cancer from India."
Also Read: Every Two Minutes, One Woman Loses Her Life To Cervical Cancer: UN
Cervical Cancer is a type of cancer that develops in layers of the cervix. It is caused by abnormal cell growth that can spread to another part of your body. There are two main types of cervical cancer. These are squamous cell carcinoma and adenocarcinoma.
Cervix is located in the pelvic cavity, about 3 to 6 inches inside the vaginal canal. It serves as the entrance to the uterus to the vagina. As per the World Health Organization (WHO), almost all cervial cancer are linked to human papillomaviruses (HPV) which are transmitted through sexual contact.
Cervical cancer has no symptoms in the early days and therefore, is hard to detect until it has spread.
Cervical cancer is largely preventable and, when detected early, highly treatable. The World Health Organization recommends HPV vaccination for girls aged 9 to 14, before they become sexually active, along with regular cervical screening from age 30, or 25 for women living with HIV.
Despite this, unequal access to vaccination, screening and treatment continues to drive higher rates of illness and deaths in regions such as sub-Saharan Africa, Central America and Southeast Asia.
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Pilot project to provide menstrual cups to school and college students in selected districts of Karnataka has been successfully implemented and now the Department of Health and Family Welfare has decided to expand the scheme across the state. The Government order noted a revised administrative approval which granted to provide 10,38,912 menstrual cups at a cost of more than Rs 61 crores through Karnataka State Medical Supplies Corporation Limited (KSMSCL) under the Swachh Bharat Abhiyan.
This decision is said to cut government expenditure on sanitary napkins by Rs 10 crores. The government spend Rs 71 crores to purchase 2,35,74,084 sanitary napkins annually to provide to beneficiaries of the Shuchi scheme. The revised order states that the department will continue distributing sanitary napkins for the next three months, after which students will be provided one menstrual cup for the following academic year.
Menstrual cups are a small, reusable intimate product used to collect period blood. It is not only good for maintaining menstrual hygiene but is also good for the environment.
Learning to use a menstrual cup properly might take some time and practice. If you have questions about which cup to choose or how to use it, your gynecologist can provide guidance. It's common to have some difficulty during the first few uses, but most people become comfortable by their third menstrual cycle. Here is how you insert it for use:
The problem arose because the menstrual cup wasn't sitting where it is supposed to be. The cup was pressing on the tube that carries urine from the kidney to the bladder, essentially blocking the flow. This blockage led to pain and other symptoms for the woman. While this is a very rare occurrence, it emphasizes the importance of understanding how the cup interacts with your body.
Lancet health explains that a poorly fitted menstrual cup can cause issues like leakage from improper fit or fullness, pain or minor injuries from insertion, rare allergic reactions, and possible urinary problems due to urethral irritation or blockage. Though infrequent, IUD dislodgement has been reported, but it's difficult to definitively link it to cup use. Infections, including the very rare toxic shock syndrome (TSS), are possible if cups aren't properly cleaned, but studies suggest they may be less risky than tampons or pads. Overall, while complications are possible, they are generally infrequent.
The size of the cup, how it's placed, how long it's used, and each person's unique body shape all play a role. Even though this kind of complication is unlikely with regular use, it's a good reminder to pay attention to how you use menstrual cups and to be aware of potential issues.
The size of the cup, how it's placed, how long it's used, and each person's unique body shape all play a role. Even though this kind of complication is unlikely with regular use, it's a good reminder to pay attention to how you use menstrual cups and to be aware of potential issues.
Credits: iStock and Wikimedia Commons
South Korean president Lee Jae Myung directed his government to consider expanding country's health insurance coverage for hair loss treatment. He remarked that hair loss has now become "a matter of survival". He calls baldness the new enemy and is quite worried by this.
As per The Chosun Daily, during a policy briefing on Tuesday, December 16, Lee asked, "Isn't hair loss part of a disease? I hear young people use a lot of hair loss medication - has there been a review?"
South Korea's national health insurance currently covers treatment for hair loss, but only those that are caused by medical conditions like alopecia areata. Most treatments for common male pattern baldness are not included in the insurance scheme, confirmed the South Korean Minister of Health and Welfare, Jeong Eun-Kyeong. Jeong explained that "genetic hair loss is not covered by health insurance due to its weak association with medical treatment". She also explained that hereditary hair loss is not covered because it is not life-threatening. Jeong explained that hair loss is considered a cosmetic concern.
However, Lee said, "Hair loss medication seems widely used—wouldn’t designating it under medical insurance lower drug prices?" He further added: "Hair loss was once seen as a cosmetic issue, but now it’s perceived as a survival matter. If costs are too burdensome, consider reviewing limits on frequency or total amounts.”
He also asked the same to be reviewed for obesity. “The same applies to obesity —are we reviewing drug treatments?” he asked. Lee also said that "there may be young people who think it’s unfair that they only pay insurance premiums and can’t receive benefits."
The Ministry of Health and Welfare has begun reviewing support for the proposal after a directive from the president, The Chosun Daily reported. This is not the first time Lee has raised the idea. He had promised insurance coverage for hair loss treatment during his unsuccessful 2022 presidential campaign, a pledge that drew criticism as populist.
Read: Why Is Your Hairline Receding?
In 2018, a local company was asked to not discriminate against aspiring job seekers for being bald-headed. The National Human Rights Commission of Korea had to intervene and said any discrimination against bald men in employment is in violation of people's rights to equality. This recommendation came after a South Korean man filed a petition in August 2015, contending he failed to land a job at a building facility management company due to his baldness.
Also Read: Are Young Men Losing Hair Over Modern Lifestyle?
Yonhap News Agency reported, that while the company denied the allegation and said the applicant failed to meet certain requirements, the commission concluded that baldness may have been the primary factor in the hiring decision. It also noted that the applicant had been asked to wear a wig during the interview.
"(Having a) bald head is a natural phenomenon that cannot be reversed by individuals. Thus any discrimination over baldness cannot be considered reasonable," the National Human Rights Commission of Korea said.
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