Credits: Canva
An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
Credit: Canva
The US Food and Drug Administration (FDA) has issued new guidance urging veterinary drug makers to define the duration of antibiotic use in livestock.
The February 2026 guidance, published by the FDA’s Center for Veterinary Medicine (CVM), aims to mitigate the development of antimicrobial resistance and protect public health. It is consistent with previous recommendations by the federal agency that promoted the judicious use of medically important antimicrobial drugs in animals.
The FDA said that the guidance is intended for sponsors of approved new animal drug applications (NADAs) and abbreviated new animal drug applications (ANADAs) containing antimicrobial drugs.
The guidance provides recommendations on how to add duration limits to medically important antibiotics used in or on the medicated feed of food-producing animals.
"The framework outlined in this guidance is intended to facilitate voluntary changes to have all medically important antimicrobial new animal drugs administered in alignment with the principles of judicious use,” the FDA said.
"This guidance provides specific recommendations on how sponsors may facilitate changes to the approved conditions of use of affected products in support of ongoing efforts to mitigate the development of antimicrobial resistance,” it added.
Currently, no limit has been set for the approved treatment in food-producing animals. As a result, farmers can use the antibiotics in animal feed for extended periods of time.
The proposed guidelines for “appropriately defined duration of use” labelling will ensure that the drug is used only when animals need it.
The regulator also called the industry to “revise the labeling to include appropriate criteria regarding when to begin and end feeding of the antimicrobial drug.”
The nonbinding guidance also suggests sponsors avoid instructions like “feed until market weight” to define the duration of use.
"The scope of this guidance is limited to those drugs that are approved for use in or on animal feed because all the approved uses of medically important antimicrobial drugs in other (non-feed) dosage forms already have appropriately defined durations of use," the FDA said.
Antibiotic use in livestock and poultry globally is intended to treat, control, and prevent bacterial infections.
However, their overuse and misuse in food-animal production threaten both animal and human health. It is because these promote the emergence and spread of antimicrobial resistance (AMR).
AMR in livestock is a major driver of the 700,000 to over 1 million annual human deaths linked to drug-resistant infections globally.
With roughly 70 per cent of global antibiotics used in agriculture, this misuse contributes to food-borne resistant pathogens and is projected to drive up to 10 million annual human deaths by 2050, as per the World Organisation for Animal Health.
FDA On Antibiotic Use In Livestock
The 2017 guidance issued by the FDA limited the over-the-counter use of medically important antibiotics on livestock.
It also required a prescription and veterinary oversight for all antibiotic use.
Later in 2018, the CVM called for all antibiotics used in the feed and drinking water of food -producing animals to have “an appropriately targeted duration of use”.
Credits: Canva
A shortage of prescription-strength co-codamol is set to continue until at least June, leaving thousands of chronic pain patients across the UK uncertain about how they will manage daily symptoms. The Scottish government has confirmed limited availability of the strongest 30/500mg tablets, while health boards warn alternative medicines may not fully cover demand.
The shortage is linked to delays in authorization by the Indian government for exporting key codeine-based ingredients needed to manufacture the drug.
Many patients say they first learned of the disruption through calls from local health services. Some have already been advised to slowly reduce their dose to avoid withdrawal symptoms.
Jocelin Harrison, who has relied on the medication for more than three decades after five spinal surgeries, said she was contacted by NHS Lanarkshire and instructed to cut down gradually.
“The only advice I’ve been given so far was to reduce the tablets and try to manage my withdrawal symptoms,” she said, as reported by the BBC.
“I was not offered any other advice or possible replacement pain killers and it’s a great worry for me and other chronic pain sufferers throughout Scotland and the UK.”
Doctors warn that abruptly stopping co-codamol can trigger headaches, nausea, sweating and a sudden increase in pain, particularly for long-term users.
Co-codamol combines paracetamol with the opioid codeine and is commonly prescribed after surgery or for persistent musculoskeletal conditions. It comes in three strengths: 8mg, 15mg and 30mg of codeine with 500mg paracetamol.
The lowest strength is available over the counter, but the stronger forms require a prescription and are widely used by patients with chronic pain. Because codeine can cause dependence, tapering rather than stopping suddenly is considered essential.
Health boards say supplies of alternative strengths are also limited, making it difficult to simply switch everyone onto another version.
Guidance issued locally states patients, except those undergoing cancer treatment, should gradually reduce usage until stopping completely. No new patients will be started on the medication until supplies stabilize.
NHS Grampian has urged pharmacists to prioritize existing stock carefully. However, it stopped short of telling patients to immediately begin cutting back, highlighting variation in local guidance.
Officials acknowledge substitutes exist, but warn they cannot meet the expected rise in demand from patients switching medicines.
Scotland’s chief pharmaceutical officer Alison Strath said the issue ultimately sits with UK-wide medicine supply systems but confirmed discussions are ongoing.
“Supply issues are expected until June 2026 and we are in regular contact with the UK government to seek assurances they are doing all they can to resolve this,” she said, adding that affected patients will be contacted directly about alternative treatment options.
The UK Department of Health and Social Care said most medicines remain readily available and manufacturers are working to restore production.
The shortage highlights the global nature of generic drug manufacturing. Medicines such as co-codamol 30/500mg are typically produced using ingredients sourced from India and China, meaning regulatory or production delays overseas can quickly affect patients at home.
For now, patients are being urged not to contact GP practices unless advised and to wait for further instructions from their health providers.
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Measles Outbreak In UK: A measles outbreak has been confirmed in London's north east area, noted the BMJ. As per the medical journal, the outbreak is among the unvaccinated children. The medical journal also noted that there have been 96 laboratory confirmed cases of measles in England between January 1 to February 9, 2026 and more than a third, which is 34 cases are from Enfield. BMJ also noted that Enfield is also the area with lowest vaccination rates.
As per the data by the UK Health Security Agency or the UKHSA, only 64.3% of 5 year-olds Enfield received both doses of the measles, mumps, and rubella or the MMR vaccine in 2024 and 2025. The majority (74 of 96, 77%) of measles cases confirmed in the UK so far this year were in children aged 10 and under. Some 64% of cases have been in London, 26% in the West Midlands, and 4% in the East Midlands.
Read: Unique Symptoms Of Measles In 2026 And How Long Does The Infection Last?
Last month, the World Health Organization revoked the United Kingdom’s measles elimination status after the virus was found to be circulating continuously for over a year.
In 2025, a child in Liverpool died after contracting measles, prompting renewed pressure on the NHS and government to address its return. England recorded 959 laboratory-confirmed cases that year. Although lower than the 2,911 cases in 2024, it still marked the highest annual total since 2012.
Vaccine uptake has steadily declined over the past 12 years. Only 84.4% of children in the UK receive both doses of the MMR vaccine by age five, far below the 95% coverage needed for herd immunity.
In late 2023, measles outbreaks were reported in the UK, which led to a surge in cases in 2024. Vaccination uptake at the end of 2024 was 92% for the first dose, however, for the second dose, it was below 82%.
Dr Vanessa Saliba, consultant epidemiologist at UKHSA said, "Infections can return quickly when childhood vaccine uptake falls - measles elimination is only possible if all eligible children receive two MMRV doses before school. The NHS is making vaccination easier, including offering the second MMRV dose earlier at a new 18-month appointment to boost uptake and support elimination goals."
Read: UK Loses Measles Elimination Status: Why Is This Disease Making A Comeback?
She also noted that children and adults must get vaccinated as NHS also offers catch-up jabs.
Dr Baharat Pankhania, from the University of Exeter, as reported by the BBC said, "Measles is an infection that can be prevented by vaccine - and it's extremely concerning that in the UK we now have pockets of low or no vaccine uptake. We urgently need to remedy this situation." Pankhania also noted that there is a need to make the access to GPs easier, and for an effort that could immunize babies in their homes and counter wrong information around vaccine safety.
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