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An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
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With the launch of generic versions of Ozempic, Wegovy, and Mounjaro, the demand for these weight loss and diabetes medications is skyrocketing in India. Amid the rising demand, there is also a surge of counterfeit jabs—often sold through unregulated online vendors—that can endanger lives.
According to a Reuters report, Indian drug regulators have seized more than 260 suspected counterfeit pens of Eli Lilly's popular obesity and diabetes drug Mounjaro, worth Rs 7 million, from the northern state of Haryana.
The suspected fake pens were recovered from a vehicle on the outskirts of New Delhi, and were kept under improper temperature conditions and appeared in different font sizes compared with the original product, which raised suspicion of being counterfeit.
The Haryana Food and Drug Control Administration has also arrested two people accused of making and selling the drugs. The primary accused did not have a pharmaceutical license and made the products at a private property, Drug Control Officer Amandeep Chauhan told Reuters. They had ordered peptides used in the drugs and other raw materials from vendors on the Chinese e-commerce platform Alibaba.
The arrested duo also sold the pens on the online marketplace IndiaMART at a 27 per cent discount to the original drug's price, Chauhan said.
While samples have been sent to government-run laboratories for confirmation, Eli Lilly and Company (India) spokesperson issued a statement welcoming the action against illicit medicines.
Noting that it "takes patient safety extremely seriously", the company stated that it's "actively supporting the investigation and will continue to work with regulatory and law enforcement authorities worldwide to protect patients from the risks of counterfeit products".
Also read: Lehengas, Diets & Now Mounjaro: The New Must-Have For Indian Brides?
The short answer: extremely. The risks go far beyond inefficacy. Some fake jabs contain:
Read More: Can Weight Loss Jabs Surge Divorce Rates? What Experts Are Saying
Counterfeit products may have
These are indicators that the medicine has not been produced by the original manufacturer or is being illegally sold in the wrong market.
Further, counterfeit drugs are often sold on social media platforms like Instagram, TikTok, or salon backrooms.
Also read: India To Strictly Inspect GLP-1 Drugs To Curb Misuse: Govt Flags Risks Amid Weight-loss Hype
Another major lure of counterfeit Ozempic/Mounjaro is the price tag—black-market versions are often heavily discounted. But remember: this comes at the cost of your health, safety, and potentially, your life.
If you’re unsure about a product, consult your pharmacist or primary care provider. Always ensure that any medication you take has been prescribed by a qualified healthcare provider and obtained from a licensed source.
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As Bangladesh grapples with a surge in highly infectious measles cases, neighboring Indian states Meghalaya and Tripura are strengthening preventive measures by ramping up vaccination drives and intensifying surveillance, particularly in border districts, to curb any potential spillover and contain the spread of the disease.
As per media reports, Bangladesh is reporting more than 1,100 suspected infections in a single day. The vaccine-preventable measles has also claimed the lives of 98 children in the country’s one of the worst outbreaks.
To strengthen early detection and response in Indo-Bangla border areas, the Meghalaya government conducted an orientation-cum-preparedness meeting last week at the Amlarem Sub-Divisional Office with district administration and health department officials, the Border Security Force, community leaders, and grassroots workers, including ASHAs and Anganwadi workers.
Dr A Khonglah, sub-divisional medical and health officer, Amlarem, informed of a few suspected cases in the state, The Times Of India reported. Khonglah noted there was “no cause for panic”, but stressed that early reporting was critical for timely testing and treatment.
In a notification issued on Monday, Meghalaya’s state health department called for stepping up surveillance in East Khasi Hills District.
“Immediate corrective measures are required in response to ongoing measles outbreaks in Bangladesh and the heightened risk in border districts and blocks. It is imperative to strengthen surveillance, early detection, reporting, and response mechanisms across all sectors in East Khasi Hills District,” the notification said.
The state health department directives include:
Similarly, Health officials in Tripura are also assessing the prevailing measles and rubella situation, with a focus on vaccination coverage and containment measures.
The officials in a review meeting focused on evaluating infection trends, immunization progress, and the effectiveness of ongoing containment strategies, Northeast Today reported.
Mission Director of the National Health Mission (NHM), Saju Vaheed A on Sunday visited Unakoti district to assess the prevailing measles and rubella situation, with a focus on vaccination coverage and containment measures.
The director reviewed data on vaccination coverage and stressed the need for close monitoring of vulnerable areas.
Also read: Measles Again On The Rise Globally: Is India At Risk?
Since the beginning of the year, India is seeing sporadic outbreaks of measles. Madhya Pradesh's Gwalior reported three outbreaks, and Morena six.
Over January and February 2026, 41 children were diagnosed with measles in Tikari village in Madhya Pradesh.
However, swift action by health authorities with proactive frontline engagement and data-driven rapid response prevented an escalation into large measles outbreaks. These sporadic outbreaks also highlighted the critical importance of measles-rubella (MR) vaccination in protecting children and communities.
As per official data, till April 19, Bangladesh recorded 3,443 confirmed measles cases and more than 23,600 suspected infections.
While over 12,000 patients have recovered, the outbreak has resulted in at least 36 confirmed deaths and 181 deaths among suspected cases, MNTV reported.
In response, Bangladesh has vaccinated more than 1.9 million children against measles and rubella in an emergency nationwide campaign.
Health Minister Sardar Md Sakhawat Husain said the situation has begun to stabilize due to early intervention, adding that vaccine supplies remain sufficient to sustain the campaign through June.
Measles is a highly contagious virus that spreads through direct contact or through the air when an infected person coughs or sneezes. It is a vaccine-preventable disease that can cause devastating complications, including blindness, pneumonia, encephalitis, and long-term immune dysfunction.
Symptoms typically appear seven to 14 days after exposure and may include:
To safeguard against measles, individuals should ensure timely vaccination, especially for children.
Maintaining good hygiene, such as frequent handwashing and covering the mouth while coughing or sneezing, helps reduce transmission.
Avoiding close contact with infected individuals and ensuring proper nutrition to boost immunity are also important.
Public awareness and community health programs play a crucial role in prevention.
Mindless use of weight loss drugs can cause the weight to return later. (Photo credit: iStock)
Weight loss drugs appeal to many for their convenience, but according to some experts, there are a number of noteworthy side effects. From rapid weight gain to sagging skin, several side effects of weight loss drugs have been identified through studies. Now, new research has found that weight loss drugs can cause more muscle loss than clinical expectations. The results, presented at the American College of Physicians Internal Medicine (ACP-IM) meeting in San Francisco, add to existing evidence on the possible adverse effects of GLP-1.
When a person loses a considerable amount of weight, they also lose bone mass, muscle mass, and some connective tissue. Experts at the University of North Carolina at Chapel Hill found that no studies directly associate muscle loss with a decline in physical function or strength. However, this clinical gap underscores the need to assess strength and mobility alongside weight loss in patients receiving this therapy. The systematic review identified 36 randomised clinical trials that measured changes in muscle mass and fat among adults using incretin-based obesity medications such as tirzepatide, dulaglutide, or semaglutide.
Each study measured body composition using MRI, CT scans, and bioelectrical impedance analysis. Most of them used DEXA along with other methods to obtain information about lean muscle mass, bone mineral density, and the distribution of body fat. The average age of participants ranged from 20 to 63.7 years. Only four studies included participants aged 60 years and above. None of the studies focused on adults aged 65 years or older.
Researchers noted a concerning trend: patients’ estimated muscle loss exceeded the 25 per cent threshold. Clinicians had expected a 25 per cent reduction, but not more than that. Experts also found that 68 per cent of people who used the drugs exceeded the 25 per cent benchmark, compared to 50 per cent of those who relied on placebos and lifestyle interventions. None of the studies measured whether the loss of muscle mass was correlated with function or strength loss.
Despite being a concerning side effect of weight loss drugs, muscle mass is likely to diminish anyway with age. Additionally, the loss is more significant in older adults. Therefore, doctors advise caution when prescribing these drugs to individuals who are more prone to losing muscle function at an advanced age. Ideally, doctors should recommend exercise or physical therapy to patients taking weight loss medications.
The final word
According to experts, weight loss drugs do have a positive side — and that extends beyond obesity treatment. These drugs are also beneficial for diabetes and help reduce the risk of cardiovascular disease. However, it is important to support treatment with the right kind of diet and a proper exercise regimen. Solely depending on the medication can lead to weight gain once it is discontinued. Therefore, for healthy weight loss, it is best to rely on sustainable methods for long-lasting results.
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