Is 'Sticky Gunk' In Your Brain The Reason Behind Alzheimer's Disease?

Updated Mar 20, 2025 | 08:53 AM IST

SummaryThe new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years.
Alzheimer's Disease

Credits: Canva

An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.

One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.

Slowing Down The Symptoms

Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.

How Was The Research Conducted?

The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.

The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.

Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”

The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.

Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.

The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.

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Ebola Outbreak: Kerala To Keep Visitors From Affected Countries Under Surveillance For 21 Days

Updated May 22, 2026 | 09:00 PM IST

SummaryThe state government of Kerala has taken several steps to prevent an Ebola outbreak in the state. Among the new guidelines, the state has mentioned a monitoring period of up to 21 days for those travelers who came from the nations affected by Ebola.
Ebola Outbreak: Kerala To Keep Visitors From Affected Countries Under Surveillance For 21 Days

Credit: Canva

Amid the rising cases of Ebola virus infection in nations like the Democratic Republic of the Congo, Uganda, and South Sudan, the whole world has gone to an alert mode. The state government of Kerala has declared that it will keep the visitors from the countries flagged by the World Health Organization (WHO) under mandatory health surveillance for up to 21 days after arrival.

The government of India has already issued an advisory on this important issue. In accordance with the direction, the state government of Kerala has also taken some strict steps to protect the general public from this infectious virus. On Thursday, at the meeting of the State Rapid Response Team, Health Minister K. Muraleedharan said the measure was being adopted as an additional precaution.

The Union Health Ministry has also propagated a stricter stance on preventing the virus outbreak in the country. The ministry emphasizes its stance by issuing orders to strictly follow the special health guidelines.

As per the new norms, the travelers from Ebola-affected nations are asked to report to the health authorities at the airport if they feel symptoms commonly associated with Ebola, like fever, headache, fatigue, vomiting, diarrhoea, muscle pain, sore throat, or bleeding. Those who had any contact with confirmed or suspected Ebola patients have also been informed by the health authorities.

The state government has made screening of passengers stricter in the international airports and seaports.

In addition to that, the authorities have also searched isolation wards and intensive care facilities throughout the state to find those who require treatment or observation.

The health minister of the state ordered ample training of healthcare personnel in infection prevention and control. There is also emphasis on the use of PPE kits, proper treatment protocols, and critical care management.

What is Ebola?

Ebola is a severe and, in most cases, deadly disease caused by viruses predominantly found in Africa. The spread of the disease happens through contact with infected body fluids.

Some symptoms can indicate a possible infection. This includes fever, weakness, headache, muscle pain, vomiting, diarrhea, sore throat, and unexplained bleeding. This eventually leads to severe complications like bleeding, organ failure, and death. The hosts of the virus are animals like bats, primates, and antelopes.

WHO Says Vaccine Could Take Months

Meanwhile, Tedros Adhanom Ghebreyesus, WHO Chief said he was “deeply concerned about the scale and speed of the epidemic”. He noted that the numbers are expected to rise given the time taken to detect the virus.

The WHO says it could take up to nine months before a vaccine against this particular species of Ebola is ready.

Two possible "candidate vaccines" against the Bundibugyo species are being developed, but neither has gone through clinical trials yet, WHO advisor Dr. Vasee Moorthy said, according to the BBC.

Speaking to journalists in Geneva, Tedros said 51 cases have been confirmed in the Democratic Republic of Congo — where the first case was reported — and two in neighboring Uganda.

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Post-Pandemic Effect: Why 30-Something Delhi-ites Are Struggling With High BP

Updated May 22, 2026 | 08:00 PM IST

SummaryThe increasing number of hypertensive individuals in Delhi has brought to light the fact that lifestyle-related ailments are not only common but also manifest at an earlier age.
High BP (1)

Hypertension is largely a lifestyle condition which can be prevented with simple daily life choices. (Photo credit: AI generated)

In the recent past, there has been an increase in the prevalence of hypertension among the young urban population of Delhi, especially after the pandemic. Medical practitioners and public health specialists note that people in their late twenties and thirties are now experiencing higher levels of high blood pressure, which used to affect mostly middle-aged and older people. This has become a silent cardiovascular disease problem among young professionals due to the fast-paced lifestyle and post-pandemic stress.

In an interaction with Health and Me, Dr Tushar Tayal, Associate Director, Internal Medicine, CK Birla Hospital, Gurugram, spoke about the rising incidence of high BP cases in 30-something Delhi locals.

Lifestyle Changes Due to the Pandemic Situation

The coronavirus pandemic brought about significant changes in people’s lifestyles. Working from home became the norm for most companies, leading to less physical exercise, more screen time, and the blurring of lines between work and private life. Young adults living in Delhi experienced disrupted sleeping schedules, spent less time outside, and consumed processed foods delivered to them regularly. These unhealthy practices have persisted even after offices reopened.

Stress and Uncertainty Persist

Moreover, life after the pandemic has also brought emotional and financial stress for many city-based working individuals. Fears surrounding job stability, the increasing cost of living, loneliness, and burnout have had an adverse effect on individuals’ mental well-being. Stress leads to the activation of the body’s “fight or flight” response, causing increased heart rates and the tightening of blood vessels. Eventually, constant physiological stress results in long-term high blood pressure. Young adults might not be aware of how stress impacts their bodies physically until something goes wrong.

Urban Life in Delhi Puts People at Risk

Furthermore, other aspects of urban life in Delhi also increase the risk of developing cardiovascular diseases. Factors such as long commutes, traffic pollution, poor air quality, lack of proper sleep, and the consumption of convenience foods have contributed to poor heart health among people. The reliance of most professionals on caffeine, processed food, and unhealthy eating habits has made people more prone to high blood pressure problems.

How Hypertension in the 30s is Hazardous

The early onset of high blood pressure predisposes an individual to various cardiovascular diseases in the future, including stroke, kidney disease, heart disease, and other metabolic problems. In most cases, high blood pressure remains unnoticed for quite a long time due to the absence of any obvious signs and symptoms. Therefore, some patients perceive headaches, fatigue, anxiety, or sleeplessness as mere side effects of stress. Nevertheless, hypertension in one’s thirties poses a threat of vascular damage in the coming decade.

Hypertension in Young Urban Adults

It seems curious that urban youth demonstrate sufficient physical activity on their Instagram accounts while being incapable of sustaining cardiovascular balance. The issue stems from the fact that regular exercise performed in the gym or during weekends cannot totally compensate for the impact of constant psychological stress, an unhealthy dietary regime, and stressful work. Specialists indicate that blood pressure is regulated not just by one’s body mass index but also by neurological factors and lifestyle stability.

Awareness Regarding Prevention from Hypertension

According to experts, individuals aged over 25 years need to monitor their blood pressure levels regularly, especially when engaged in stressful jobs. Other preventive measures, such as walking daily, reducing sodium consumption, practicing yoga and meditation, getting adequate sleep, and managing stress, will greatly contribute towards mitigating risks. Initiatives by corporate organisations, as well as government campaigns, might be instrumental in raising awareness regarding the prevention of hypertension among the youth in Delhi.

The post-pandemic period has clearly shown that stress, lack of physical activity, and the challenges of living in cities have a great bearing on cardiovascular disorders.

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Singapore Reports 12,700 COVID Cases: Know All About NB.1.8.1 Variant

Updated May 22, 2026 | 06:00 PM IST

SummaryThe NB.1.8.1 variant is currently the dominant strain circulating in Singapore and accounts for more than half of locally sequenced cases. The variant was classified as a “Variant Under Monitoring” (VUM) by the World Health Organization in May 2025.
Singapore Reports 12,700 COVID Cases: Know All About NB.1.8.1 Variant

Credit: iStock

Singapore is seeing a significant rise in COVID-19 cases, driven by the NB.1.8.1 variant from the Omicron family, nicknamed “Nimbus”.

According to a statement from the Communicable Diseases Agency, the number of COVID cases in Singapore rose to 12,700 in the week of May 10 to May 16, compared with 8,000 in the previous week.

The country is also seeing a rise in the number of daily COVID hospitalizations — from 56 to 73 during the same period, with one case in the intensive care unit daily on average, the CDA said.

NB.1.8.1 Variant Driving COVID Surge: Should People Be Worried?

The NB.1.8.1 variant is currently the dominant strain circulating in Singapore and accounts for more than half of locally sequenced cases.

The CDA noted that people at extremes of age, such as those aged 60 years and above, including those staying in aged care facilities, and medically vulnerable people aged six months and above, are at increased risk of severe COVID infection and should stay updated with vaccinations.

Calling the increase a “periodic wave” of COVID that “is expected throughout the year”, the agency said it is monitoring the spike.

Singapore Reports 12,700 COVID Cases: Know All About NB.1.8.1 Variant

“There is no indication that the variants circulating locally are more transmissible or cause more severe disease compared with previously circulating variants,” it added.

The CDA noted that the surge in cases may be due to waning population immunity, and stated that the currently available vaccine in the country continues to be effective for protection against this variant..

Also read: Child Mortality Rates In US Saw A Massive 6.6% Rise In Just 3 Years, Study Finds

All About The NB.1.8.1 Variant

NB.1.8.1 was first detected in January 2025. It is a “recombinant” variant, meaning it formed when two or more older variants mixed their genetic material.

On May 23, 2025, the World Health Organization (WHO) classified NB.1.8.1 as a “Variant Under Monitoring” (VUM). Scientists have identified changes in the virus that could affect how it spreads or infects people, although evidence is still evolving.

Previous laboratory studies also suggest the variant binds more tightly to human cells, indicating it may infect people more effectively than earlier variants.

Symptoms Linked To NB.1.8.1

People infected with NB.1.8.1 commonly report:

  • Sore throat
  • Cough
  • Fever
  • Muscle aches
  • Stuffy or runny nose

Some patients also experience:

  • Nausea
  • Diarrhoea
  • Fatigue
  • Mild cough
  • Nasal congestion

One unusual symptom linked to the variant is a severe “razor blade” sore throat, where people report sharp pain while swallowing food or beverages.

Read More: Europe Sees Record Surge In Gonorrhea, Syphilis Cases In Over A Decade: ECDC

How To Protect Yourself From Severe COVID-19

Vaccination remains the best protection against severe illness, especially for:

  • Older adults
  • Immunocompromised individuals
  • People with underlying medical conditions
  • Medically vulnerable individuals aged six months and above

Other Safety Measures

Authorities advised the public to continue basic preventive practices such as:

  • Washing hands regularly
  • Covering the nose and mouth while coughing or sneezing
  • Wearing masks when symptomatic
  • Avoiding unnecessary social interactions when unwell.

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