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An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
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The New World Screwworm fly is a devastating tropical species that majorly infects cattle but can also be harmful to humans in some cases, and this problematic species, after being contained in the southern states of the US, is suspected to return once again, according to the officials of the United States Department of Agriculture (USDA).
This debut may cause mayhem in the cattle industry. The USDA has posted on the social platform X that it was testing a sample from a potential infestation of the fly’s flesh-eating larvae at its national veterinary lab in Iowa. The exact location of this suspected case has not been stated.
U.S. Agriculture Secretary Brooke Rollins also said on social site X that she has met with Texas officials, including Gov. Greg Abbott, about 50 cattle ranchers. She added that the potential case was “being fully contained.”
This very important announcement came just after Rollins held an online news conference to shed light on the proximity of the threat, as it was detected in Mexico, only 25 miles from the state.
New World Screwworm Fly is an invasive tropical species whose females lay eggs in open wounds or mucous membranes. These eggs then hatch and eat flesh. This trait makes them a unique flying species. This species is known to infest livestock, wild mammals, and household pets. Though it's rare, humans can also be infested by this threatening species.
The recent case of Maryland, where federal health officials confirmed that a person got infested by this fly after visiting El Salvador, but the patient recovered soon. The last large-scale infestation happened in 2016 when it spread among wild deer in Florida.
Also Read: Donald Trump: As The President Boasts Cognitive Test Score - Truth Social Posts Suggest Otherwise
The infestation of this invasive species has been done before, and the process involves breeding sterile male flies and releasing them to mate. This process completely eradicates the population. In 2024, this very species was contained in Panama by this same process.
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The USDA is very active and cautious about this possible outbreak in the states; it has dedicated 21 million US dollars to convert a fruit-fly breeding facility in southern Mexico into one for breeding screwworm flies. It has also opened a new center for dispersing sterile flies bred elsewhere in southern Texas. Along with these, the government agency is building a screwworm fly factory in Texas with 750 million.
The Agriculture Secretary was also alarmed by this possible outbreak and ceased cross-border livestock import from Mexico last year. She has stressed that pets can travel across borders with families and can get infected. The wild animal can also travel through the border and get infected with it and return. Though the US authorities have assured, stating, “Our food supply is 100 per cent safe.”
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The US Centers for Disease Control and Prevention (CDC) has given a warning on having cosmetic surgeries in foreign nations, as it can cause serious infection, even in some cases, death.
CDC, in its report, has shed light on the fact that aesthetic surgeries such as breast augmentation, liposuction, and other elective procedures are performed both within the United States and abroad. This cosmetic enhancement is causing growing concern for public health.
CDC’s journal Emerging Infectious Diseases also published a study regarding the danger and fatality surrounding the beauty enhancement surgeries. This study screened over 2,100 reports of U.S. citizens who travelled in foreign nations between 2014 and 2024.
This CDC research identifies 21 reports involving approximately 145 patients who experienced severe adverse health effects after undergoing beauty enhancement procedures within and outside the US. Notably, four out of these patients even died due to having these surgeries.
The report also mentioned the reasoning behind this alert, as many of these clinics and facilities are causing infections and even death due to their outdated and careless infection-control practices, which include improper environmental cleaning, lack of use of personal protective equipment, a shortfall in hand hygiene, and repeated use of some surgical instruments.
Kiara McNamara, a CDC nurse epidemiologist and lead author of the study, said, “More and more people are getting medical procedures outside the United States, but there are risks.”
The CDC has urged U.S. nationals to research thoroughly before having cosmetic procedures in healthcare facilities abroad.
Also Read: Donald Trump: As The President Boasts Cognitive Test Score - Truth Social Posts Suggest Otherwise
The United States is once again witnessing a surge in norovirus infections, a highly contagious gastrointestinal illness that causes severe vomiting and diarrhea.
Media reports noted that hikers along Southern California's Pacific Crest Trail have been hit by a fast-spreading outbreak of what is often referred to as the "winter vomiting disease".
At least two dozen hikers have fallen ill along the trail over the past two weeks, resulting in at least one air rescue. Health officials believe the cases are linked to norovirus, USA Today reported.
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In addition, the latest data from the US Centers for Disease Control and Prevention's National Respiratory and Enteric Virus Surveillance System also showed that norovirus cases have increased over several weeks following a sharp seasonal decline that began in March.
About 11.2 per cent of administered norovirus tests returned positive during the week ending April 28. That figure rose to 12 per cent in the week ending May 2.
Norovirus is commonly associated with the colder months, when respiratory illnesses such as flu and the common cold are widespread.
However, health experts note that late-spring increases in norovirus activity are not unusual, and outbreaks can occur throughout the year due to the virus's highly contagious nature, the report said.
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President Donald Trump is boasting about his cognitive test score and claiming he has the highest score possible, but his comments on Truth Social have started a debate that questions the test itself.
President Trump is saying that he had a perfect score of 30 out of 30 in the cognitive test at Walter Reed National Military Medical Center, which, according to him, is a sign of “extreme intelligence.” On the other hand, experts are at odds with him in this regard, as the whole test is for screening cognitive function, not for calculating intelligence.
The president is saying that he has achieved a full score in a very difficult test. He said, “Unlike other US Presidents, none of whom have ever taken an approved, high difficulty, Cognitive Test, I scored a perfect 30 out of 30, considered ‘extreme intelligence.’”
“In fact, this is my fourth such test, all PERFECT or 120 correct answers out of 120 questions asked! Anyone rarely gets a Perfect Score, especially when achieved four times in a row.” He wrote in his post.
He also demanded that the candidates for president and vice president should also go through this kind of test by saying, “In fact, this is my fourth such test, all PERFECT or 120 correct answers out of 120 questions asked! Anyone rarely gets a Perfect Score, especially when achieved four times in a row.”
Also Read: US CDC Health Alert: Deadly Risks and Infections Linked to Cosmetic Surgeries Abroad
Trump’s claims were immediately questioned by experts like Dr. Jonathan Reiner and Abby Phillip of CNN. They argued that repeated tests may not provide the same value. According to them, as the president had taken the test several times and the questions didn't change that much, it was easy. Other than that, the test is not designed to calculate intellect; it is more of a dementia screening test.
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According to experts, the physical examination lacks detailed results from tests used to assess cardiovascular health.
Barbabella’s description of Trump’s cardiac health cites results from a coronary CT angiography, an echocardiogram, and an artificial-intelligence-enhanced electrocardiogram analysis.
Jonathan Reiner, Professor of Medicine and Surgery, Interventional Cardiologist, in a post on social media platform X, questioned the need for another coronary artery CT on Trump, as he was last scanned in October.
"We don’t typically scan patients 6 months later unless we are concerned about a finding on the initial scan. What prompted the repeat CT?" he said.
Further, Trump’s cholesterol numbers and medication regimen also attracted attention from physicians who reviewed the memorandum.
According to the report, his HDL (good cholesterol) level was 70 mg/dL, while his LDL (bad cholesterol) level was 53 mg/dL.
The report said Trump takes rosuvastatin and ezetimibe for cholesterol management.
“He’s got like the best cholesterol numbers you’ll see,” said Daniel Torrent, adding that it is unusual for medication alone to achieve such favorable values. “We don’t usually manage people to the point where they’re that good.”
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