Is 'Sticky Gunk' In Your Brain The Reason Behind Alzheimer's Disease?

Updated Mar 20, 2025 | 08:53 AM IST

SummaryThe new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years.
Alzheimer's Disease

Credits: Canva

An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.

One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.

Slowing Down The Symptoms

Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.

How Was The Research Conducted?

The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.

The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.

Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”

The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.

Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.

The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.

End of Article

Adenovirus Cases Rise In UK, Health Authorities On Alert

Updated Dec 25, 2025 | 09:08 PM IST

SummaryAfter a harsh superflu season, adenovirus has emerged as a fresh concern in the UK. The highly contagious virus causes cold or flu-like symptoms but can trigger stomach illness and complications. Though there is no specific treatment, hygiene helps. Reassuringly, recent lab data shows adenovirus cases are currently declining nationwide overall now.
Adenovirus Cases Rise In UK, Health Authorities On Alert

Credits: Canva

Adenovirus, or what some people are calling the mystery disease is going to be the next worry in the UK, after superflu had already grappled the healthcare system. Along with H3N2 and its variant superclade K, people are now worrying about this mystery disease.

Adenovirus is highly contagious and causes mild cold or flu-like symptoms, though severe cases could lead to stomach flu and vomiting. Many describe this virus as 'heartier' than others. The reason is that the virus can survive longer on surfaces and even resist the common disinfectants used. This is what makes it highly transmissible.

Is There Any Treatment For Adenovirus?

As of now, there is no treatment for adenovirus, it could however be managed and monitored. What helps is regular handwashing and thorough cleaning of surfaces.

The good news is that cases of adenovirus are actually dropping in the UK, as confirmed lab reports. The cases last week were 1.2 per cent, whereas the week prior, it was at 1.7 per cent, as also reported by the Independent.

What Are The Symptoms Of Adenovirus?

While a lot of the symptoms mimics of those in flu or COVID, including shortness of breath, a sore throat and or a runny nose. However, there are certain unique symptoms of adenovirus that include:

  • Diarrhea
  • Pink Eye or conjunctivitis
  • Ear infection or otitis media
  • Swollen lymph nodes
  • Pneumonia
  • Stomach pain
  • Nausea
  • Vomiting

Other rare symptoms could also include impact on your bladder or nervous system. As viruses in your bladder can also cause urinary tract infections, and the same virus in your nervous system can cause condition that can affect your brain. These conditions also include encephalitis and meningitis.

The symptoms usually start to subside within two days, however, if the symptoms stay even after three days without any relief, it might be a red flag. The best thing to do during such a situation is to go consult your GP.

Also Read: Unique Symptoms Of Mysterious Adenovirus And How Long Infection Now Last

Is Adenovirus Spreading Faster Than Flu and Covid?

Experts have noted that due to its ability to stay longer in the environment and being highly transmissible, it is in fact, spreading faster than flu and COVID. Eric Sachinwalla, Jefferson Health's medical director said that this virus is still unfamiliar and thus not much can actually be done to treat adenovirus. Speaking to PhillyMad, he said, "It is pretty contagious because it is heartier than other viruses - soap and water, or everyday disinfectant, won't kill it, so it tends to live in the environment longer."

What Are The Ways To Stay Safe From Adenovirus?

Since adenovirus spreads through close contact and is resistant to many everyday disinfectants, hygiene remains the key. The best way to stay safe is by avoiding close contact, especially with those who are unwell. You may also keep an eye on your symptoms, including your body temperature and take steps to prevent the virus from spreading by taking precautions, as well as getting the flu jab.

End of Article

WHO Approves Two COVID-19 Rapid Antigen Tests, Check The Details Here

Updated Dec 25, 2025 | 10:12 AM IST

SummaryWHO has fully prequalified two COVID-19 rapid antigen tests—SD Biosensor STANDARD Q and ACON Flowflex—after their earlier emergency use during the pandemic. The move confirms long-term quality, safety and accuracy, enabling bulk procurement and wider access. With COVID-19 still circulating, these tests remain crucial, especially in low-income countries with limited testing.
WHO Approves Two COVID-19 Rapid Antigen Tests, Check The Details Here

Credits: iStock

The World Health Organization (WHO) on December 24 prequalified two rapid antigen diagnostic tests (Ag-RDTs) for SARS-CoV-2. This virus is known to have caused COVID-19. As per the WHO, these two tests are called SD Biosensor STANDARD Q COVID-19 Ag Test and the ACON Biotech Flowflex SARS-CoV-2 Antigen Rapid Test (Self-Testing).

At first these tests got temporary emergency approval from the WHO during the pandemic. This was done so the countries could start using them quickly even though long-term data was limited. This emergency approval helped the tests reach over 100 countries when they were urgently needed.

What Has Changed Now?

The WHO has now given these tests full prequalification, which means it has a stronger and long-term approval. This means that the WHO has thoroughly checked and confirmed that the tests consistently meet global standards for quality, safety, and accuracy.

Why Does This Matter?

  • The tests can now be officially bought and used by global organizations and governments
  • They can be included in bulk purchasing to lower prices and increase supply
  • This makes reliable COVID-19 testing more affordable and accessible, especially in low-and middle-income countries

COVID-19 Is Far From Being Over

Even though WHO officially ended COVID-19 emergency phase over two years ago, the virus is still circulating globally. In fact, this year, we have seen variants of COVID-19 circulating around, causing the most unique symptoms, including razor-blade like throat. Variants like JN.1, Stratus, Nimbus, LP8.1, and BA.3.2 were all that we saw in 2025.

While the good news is that infection levels are relatively stable, but the virus has not completely disappeared and testing is still necessary, especially in poorer countries.

Many low-income countries do not have easy access to labs or expensive PCR testing. So there is still a need for a strong, but cheaper and reliable way to detect COVID-19, and these tests may as well do that.

Why Rapid Antigen Test Matters

  • Give results in 15–30 minutes
  • Cost less than PCR tests
  • Don’t require labs or specialized equipment
  • This means they can be used in small clinics, community centers, mobile vans, or remote areas, where lab testing isn’t practical.

However, it is important to note that rapid antigen tests are not replacement for PCR tests. They simply complement the PCR tests by allowing faster, on-the-spot decisions, especially when the lab capacity is limited.

What Makes It Essential Today?

Rapid antigen tests could help with spotting and stopping local outbreaks quickly, protecting high-risk people and healthcare workers, and staying prepared for future respiratory pandemics.

The WHO is also pushing for decentralized, quality-checked testing as part of universal healthcare and global health security, so countries aren’t caught unprepared when the next outbreak happens.

When Is It A Right Time To Get Yourself Checked For COVID-19?

If you notice these following symptoms as noted by the Centers for Disease Control and Prevention (CDC), it is best that you get yourself a COVID-19 test:

  • Fever or chills
  • Cough
  • Shortness of breath or difficulty breathing
  • Sore throat
  • Congestion or runny nose
  • New loss of taste or smell
  • Fatigue
  • Muscle or body aches

End of Article

Singapore, UK and Canada Issue Health Advisory Over Delhi’s Air Pollution

Updated Dec 25, 2025 | 04:00 AM IST

SummaryAs Delhi’s air pollution worsens, Singapore, the UK and Canada have issued health advisories for their citizens travelling to the capital, warning of serious health risks. Despite GRAP Stage 4 measures and official reviews, Delhi’s air quality remains very poor to severe, with high AQI levels affecting residents and travellers alike.
Singapore, UK and Canada Issue Health Advisory Over Delhi’s Air Pollution

Credits: iStock

As Delhi's air quality levels and pollution continues to worsen, and people struggle to breathe, countries like Singapore, the United Kingdom, and Canada issued advisories for their citizens travelling to the capital city. However, the capital city's crisis continues to remain ignore, though CM Rekha Gupta did hold a review meeting on the same on Monday, with a follow-up scheduled on Thursday.

Singapore Travel Advisory On Delhi's Air Pollution

Singapore High Commission issued an advisory, which stated:

On 13 December 2025: The Indian Central Pollution Control Board invoked Stage 4, the highest level, of the Graded Response Action Plan (GRAP) in the Delhi National Capital Region. Under GRAP 4, construction and industrial activities are heavily restricted, and schools and offices are encouraged to shift to hybrid format. The Delhi authorities have urged residents to stay indoors, especially children and those with respiratory or cardiac ailments, and to use masks if stepping out. In this regard, the High Commission urges Singapore nationals in the Delhi National Capital Region to pay heed to this advice.

We also note that given the low visibility, flights to and from the Delhi National Capital Region are likely to be affected. The Indira Gandhi International Airport and several airlines have issued advisories. Travellers should take note of this, and check with the respective airlines for updates.

UK And Canada Too Issue Advisories On Delhi Pollution And Its Impact On People

UK's Foreign, Commonwealth & Development Office (FCDO) warned that air pollution could lead to serious health threats for those living in northern India, especially between the months of October and February. The UK advisory also stressed on the health of pregnant women and people with any heart or respiratory. The advisory noted that they must seek medical advice before travelling to India.

The statement read: Children, the elderly and those with pre-existing medical conditions may be especially affected. If you’re pregnant or have a respiratory or heart condition you may wish to consult a medical practitioner before you travel.

Canada too issued a similar notice, advising, especially those who are already struggling with respiratory issues and to continuously monitor air quality levels. The notice also highlighted the pollution that is caused by fog and smoke trends that are increasing in urban areas like Delhi, especially during the winters.

The advisory read: Smoke haze and other types of air pollution can be extremely hazardous in urban areas and cities such as Delhi. It’s typically at its worst in winter. In rural areas, air quality can be affected by agricultural burning. Dust storms also occur across northern India. Monitor air pollution levels, which change quickly, especially if you suffer from respiratory ailments or have pre-existing medical conditions.

As of today, Delhi's air quality remained in "very poor" category, and the AQI stood at 342 at 8am, as per the Central Pollution Control Board. The 24-hour average AQI was logged at 412 under the "severe" category on Tuesday evening when Delhi's quality peaked to record the fourth severe air day in the month of December.

End of Article