Is 'Sticky Gunk' In Your Brain The Reason Behind Alzheimer's Disease?

Updated Mar 20, 2025 | 08:53 AM IST

SummaryThe new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years.
Alzheimer's Disease

Credits: Canva

An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.

One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.

Slowing Down The Symptoms

Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.

How Was The Research Conducted?

The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.

The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.

Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”

The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.

Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.

The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.

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US HHS Accuses 200+ Hospitals Of Improperly Billing Over 120 Million For Gender-Related Care In Minors

Updated Aug 19, 2026 | 08:11 AM IST

SummaryThe US Department of Health and Human Services (HHS) recently accused several hospitals of fraudulent insurance coding in gender-related treatments for minors.
US HHS Accuses 200+ Hospitals Of Improperly Billing Over $120 Million For Gender-Related Care In Minors

Credit: AI

The US Department of Health and Human Services (HHS) has accused more than 200 hospitals and healthcare providers of using improper insurance billing codes to obtain coverage for gender-related medical treatments provided to minors.

The allegations are part of a new HHS report, Wolves in White Coats: How Doctors and Hospitals Pushed and Profited from the Fraud of “Gender Medicine”, released this month. The report examines insurance coding, financial incentives and the provision of what the agency calls “sex-rejecting procedures” to children.

According to HHS, its review identified nearly $120 million in insurance claims since 2019 involving treatments like puberty blockers and hormone therapy.

The agency alleges that some providers used diagnostic codes unrelated to gender dysphoria, including codes for conditions like early puberty or unspecified hormonal disorders, to secure insurance reimbursement.

Allegations By HHS

At the centre of the report is medical billing, rather than simply whether a particular treatment was provided. HHS alleges that some hospitals coded gender-related treatments under diagnoses that could make the procedures eligible for insurance coverage.

The department argues that this amounted to fraudulent or improper billing because the codes allegedly did not accurately describe why the treatment was being provided.

The report names several major healthcare institutions, including Mount Sinai Hospital and Boston Children's Hospital, according to Reuters.

HHS says the review covered procedures including puberty blockers, cross-sex hormones and surgeries. The report estimates that nearly $120 million in insurance charges were associated with the treatments examined since 2019. HHS argues that financial incentives helped drive the expansion of pediatric gender-related services.

The agency's report also claims that hospitals and physicians could benefit financially from establishing long-term treatment relationships with patients.

However, an allegation in an HHS report is not the same as a finding of fraud by a court or a final determination by an insurer. Individual billing and claims would need to be investigated to establish whether fraud actually occurred.

Also read: What Trump’s Childhood Vaccine Order Means: When Will It Take Effect?

Part Of Trump's Broader Effort To Restrict Gender-Related Treatments

The report is part of the Trump administration's broader effort to restrict gender-related medical interventions for minors.

The administration has already taken steps affecting federal funding. Earlier this month, the Centers for Medicare & Medicaid Services finalized a rule ending federal Medicaid and CHIP funding for certain gender-related procedures for children and young people.

HHS Secretary Robert F. Kennedy Jr.'s department has framed the issue as one involving both patient safety and the use of public and private healthcare funds.

Also read: Kennedy Announces Food Policy Reforms Under Trump’s MAHA Agenda: What Has Been Proposed?

Hospitals And Gender-Affirming Care Supporters React

Supporters of gender-affirming care argue that treatments such as puberty blockers and hormones can be medically appropriate for some adolescents with gender dysphoria and that access to such care can be important for mental health and wellbeing.

Reuters reported that supporters of the treatments dispute the HHS's characterization of the care. Boston Children's Hospital said it was reviewing the findings, while the American Hospital Association did not provide a comment to the news agency.

The allegations could lead to further scrutiny of hospitals' billing records and potential investigations into whether insurers or government health programmes were improperly charged.

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Congo's Ebola Outbreak Is Spreading Fast But WHO Says It Can Still Be Contained In 3 Months

Updated Aug 19, 2026 | 07:16 AM IST

SummaryA WHO official recently said that the Ebola outbreak in DR Congo can be contained within three months if they get the resources they need.
Congo's Ebola Outbreak Is Spreading Fast But WHO Says It Can Still Be Contained In 3 Months

Credit: AI

The Democratic Republic of Congo's Ebola outbreak has become the deadliest in the country's history, with more than 2,300 deaths and almost 5000 cases reported. Yet the World Health Organization (WHO) says the outbreak can still be brought under control within the next three months if they get the resources they urgently need.

The outbreak, caused by the Bundibugyo species of Ebola virus, was declared in May and has now spread to six provinces. At least 2,325 people have died among nearly 4,945 confirmed cases, according to Reuters.

It has already surpassed the previous record for deaths from Ebola in the DRC and has become the second-deadliest Ebola outbreak ever recorded globally, behind the 2014-2016 West African epidemic.

The situation has turned grim as health teams are struggling to keep pace with transmission. Around 70% to 80% of new cases have no known link to previously identified infections, suggesting that the virus is spreading through chains that surveillance teams have not yet detected.

WHO Says The Outbreak Can Still Be Contained

Despite the alarming numbers, WHO officials say the window for containment has not closed and that it can be controlled within the next few months.

Thierno Balde, WHO's regional emergency director for Africa, said the outbreak could still be brought under control within three months if sufficient resources are made available.

“About the next plan for the three months, yes, if you have the necessary resources, I think it will be possible to do that,” Balde told Reuters.

One of the biggest problems in front of the authorities is that the response is underfunded. Of the estimated $115 million needed for the next phase of the response, only about 60% has been raised.

WHO is therefore pushing for additional international support while attempting to expand surveillance, treatment and community-level response.

Also read: DR Congo Ebola Outbreak Becomes Deadliest In Country's History As Death Toll Hits 2,325

Why Is This Ebola Outbreak Challenging To Control?

One of the biggest challenges is that health workers are finding many infections outside the existing contact-tracing network.

Normally, once an Ebola case is identified, teams trace people who have been exposed, monitor them and rapidly isolate anyone who develops symptoms. That system becomes much less effective when people with Ebola have no known connection to an existing case.

Conflict and population movement are contributing to the expanding outbreak. WHO has warned that the response is taking place in a remote and densely populated setting.

Health workers are also struggling with limited resources and delayed salaries. Several reports of protests among Ebola response workers over unpaid wages also surfaced recently.

Also read: Ebola Outbreak Is Claiming 1 Life Every 30 Minutes In DR Congo: UN Humanitarian Official

Course Of Action For Next 3 Months

The current epidemic is caused by Bundibugyo virus, rather than the Zaire Ebola virus responsible for some of the largest previous outbreaks.

There is currently no approved vaccine or specific treatment for Bundibugyo Ebola, although candidate vaccines and treatments are being evaluated. WHO has said work is underway to test promising candidates.

WHO's three-month target does not mean the outbreak will automatically end in 90 days. It means health authorities believe rapidly scaling up the response could still interrupt transmission before the epidemic becomes even more difficult to control.

The response is already being expanded, with additional treatment capacity, including around 400 new beds, and more epidemiologists being deployed to affected areas.

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UK Gel Nail Ban: Why the Key Chemical Was Banned And What It Means For Salons

Updated Aug 18, 2026 | 09:57 PM IST

SummaryThe European Union banned TPO in cosmetic products from September 1, 2025. The ban follows several animal studies that linked TPO to long-term fertility damage and reproductive issues.
UK Gel Nail Ban: Why the Key Chemical Was Banned and What It Means for Salons

Credit: iStock

A key chemical used in many gel nail polish products has been banned in England, Wales and Scotland.

The “gel nail ban” applies to one ingredient — Trimethylbenzoyl Diphenylphosphine Oxide, commonly known as TPO. It is used in some gel manicures to help the polish achieve a glossy finish and cure properly.

What Is TPO?

TPO (Trimethylbenzoyl Diphenylphosphine Oxide) is a photoinitiator commonly used in UV- and LED-cured nail products. It makes the varnish more durable and helps it hold its color for longer.

When Did the Gel Nail Ban Start?

The European Union banned TPO in cosmetic products from September 1, 2025. In the UK, the ban came into effect on August 15.

The ban means manufacturers can no longer sell new products containing TPO. However, salons can continue to offer gel manicures using existing TPO-containing products until February 14, 2027, or until their stocks run out.

Nail technicians will not be able to purchase new stock containing TPO. TPO-containing products continue to be used in the US, Australia and Asia.

Why Has TPO Been Banned in the UK?

The ban follows several animal studies that linked TPO to long-term fertility damage and reproductive issues.

Caroline Rainsford, Director of Science at The Cosmetic, Toiletry and Perfumery Association (CTPA), said the EU ban was based on the chemical's hazardous properties and how a substance might behave in a “worst-case” situation when the body is exposed to a very large amount.

“This is not how TPO is used in cosmetics. The amount of this ingredient used in nail products is over a thousand times less than the amount which could have any negative effect on fertility, and these products are applied to the nail, so the potential for the ingredient to be absorbed into our bodies is even smaller,” Rainsford was quoted as saying in media reports.

What Will Salons Use Instead?

TPO is used only in some gel polishes and is not found in traditional air-dried nail polishes. There are already TPO-free gels on the market, and many salons use these products. While some alternatives may belong to the same chemical family, different compounds have different safety ratings.

TPO-free gel systems now use alternative photoinitiators that meet regulatory standards while still delivering similar results.

TPO-free options are available across:

  • Gel polish
  • Builder gels
  • BIAB-style systems
  • Extension and overlay products

How to Maintain Healthy Nails

To keep your nails strong and healthy, follow these essential tips:

  • Include foods rich in omega-3 fatty acids, lean proteins, and iron.
  • Hydrate your nails with regular moisturizing to keep them from becoming brittle.
  • Trim nails when they are soft and don't cut too far down.
  • Select non-toxic polishes and minimize use of harsh removers.
  • Replace stress-relief activities with stress balls to break nail-biting habits.
  • Smoking stains nails with nicotine and damages overall nail condition.

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