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An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.
One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.
Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.
The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.
The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.
Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”
The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.
Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.
The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.
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Fiji has declared a national HIV emergency after recent reports and estimates showed that around one in every 60 adults may now be living with HIV.
The estimate has sparked concern as it marks a sharp rise from about one in 167 adults five years ago.
Fiji recorded more than 2,000 new HIV diagnoses in 2025. Health officials have attributed the grim development to unsafe injecting practices, lack of sterile equipment and major gaps in HIV treatment and prevention.
Health Minister Dr Atonio Lalabalavu said the scale and reach of the epidemic required a response that is more effective than existing outbreak measures.
“The findings also show the seriousness of the epidemic and the gaps we must close in prevention, treatment and continuing care. We have acted on that evidence. An outbreak-level response is no longer sufficient. The Ministry of Health cannot meet this challenge alone. It requires coordinated action across Government, alongside communities and our partners.”
Health officials and HIV experts have identified injectable drug use, especially meth, as a major driver of the current surge.
The concern is not methamphetamine abuse itself transmitting HIV. The risk arises when people who inject drugs share needles and syringes to ingest the drugs.
Dr Jason Mitchell, chair of Fiji’s National HIV Outbreak and Cluster Response Taskforce, said, “Fiji is currently navigating the fastest-growing HIV epidemic in the world, and what is driving this epidemic now is risky injecting drug use of people who currently inject methamphetamines.”
He added, “The unavailability of sterile needles and syringes has resulted in people who use drugs sharing needles, syringes and drug-mixing equipment.”
UNAIDS has previously highlighted the scale of the change. It reported that new HIV infections in Fiji had increased tenfold since 2014, while only 36% of people living with HIV were estimated to know their status in 2024 and just 24% were receiving treatment.
Also read: Thailand’s HIV Cases Cross 550,000 In 2026; Over 25,000 Among 15–24s
Finding people with HIV is only the first step. They need to remain connected to treatment to contain transmission.
Recent reports found that the proportion of diagnosed people receiving antiretroviral therapy had fallen from more than 98% before 2021 to around 56%.
“We are now finding people faster than we are able to keep them in care,” Mitchell said.
Antiretroviral therapy suppresses HIV in the body and allows people living with HIV to lead long, healthy lives.
When treatment reduces the virus to an undetectable level, people do not sexually transmit HIV, a principle known as U=U, or undetectable equals untransmittable.
The government says its response will include expanded HIV testing and treatment, greater access to pre-exposure prophylaxis (PrEP) and the introduction of a formal needle and syringe programme.
It also plans to strengthen its follow-up care system so people diagnosed with HIV remain connected to treatment.
The emergency declaration comes as HIV prevalence among women attending antenatal care has reached around 2%, or about one in 50 pregnant women.
That figure raises the concern of mother-to-child transmission. HIV can be transmitted during pregnancy, childbirth or breastfeeding, but effective treatment and preventive care can dramatically reduce this risk.
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Delhi has reported 121 dengue cases so far in September, taking the city’s total this year to 432, according to recent data from the Municipal Corporation of Delhi (MCD).
September has recorded the highest number of dengue cases in a single month so far this year, accounting for more than a fourth of the total cases as the monsoon season continues.
The month has also recorded the highest number of malaria cases so far this year, with no malaria-related deaths reported, according to MCD data.
The Delhi reported 90 dengue cases in August. Malaria cases rose from 17 in July to 53 in August, taking the cumulative malaria tally to 119 by the end of August, according to the MCD.
Also read: ICMR Study Shows Pune Dengue Mosquitoes Resistant To Insecticides: What It Means for Public Health
According to the MCD’s weekly vector-borne disease report, the national capital recorded 71 new dengue infections over the past week alone.
West Delhi has reported the highest number of dengue cases this year, with 57 cases, followed by Central Delhi with 54 and Shahdara North with 50.
Delhi had reported 619 dengue cases during the corresponding period in 2025, compared with 709 in 2024, 2,097 in 2023 and 295 in 2022.
Delhi has recorded 183 malaria cases so far this year, including 64 cases in September, the highest monthly figure reported this year. However, no malaria-related deaths have been reported, the MCD data showed.
The capital has also recorded 24 chikungunya cases so far this year, compared with 46 during the corresponding period in 2025. Two chikungunya cases have been reported in September so far.
Temperature and other environmental conditions can affect mosquito survival, reproduction and biting behaviour, as well as how quickly the dengue virus develops inside the mosquito.
Warmer conditions can create more favourable conditions for dengue transmission and potentially expand the areas where dengue-carrying mosquitoes can survive.
Recently released WHO's Global Public Health Situation Analysis – El Niño 2026 also identified India among countries facing high or very high health risks as El Niño event is on its way to alters weather patterns across South Asia.
El Niño is a periodic warming of surface waters in the central and eastern tropical Pacific Ocean that can disrupt weather patterns around the world.
As per the WHO assessment identified India is at high or very high risk, with most of South Asia, for a drier-than-normal conditions and above-normal heat during August-October.
Such changes in temperature and rainfall can influence mosquito populations and the transmission of vector-borne diseases.
READ: Dengue Is Spreading Beyond Monsoons And Into New Regions Across India, Says Expert
To lower your risk of dengue and other mosquito-borne diseases:
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Pakistan-made skin lightening creams that Indian regulators warned consumers against are still showing up on online marketplaces. This has raised concerns about how unauthorised cosmetics are reaching buyers despite regulatory restrictions.
The Central Drugs Standard Control Organisation (CDSCO) has issued a public health alert against Goree Beauty Cream and Chandni Whitening Cream, both produced in Pakistan.
The regulator said the creams were not registered for import into India and contained excessive heavy metals beyond specified limits, which could have toxic effects.
Some of the products listed on marketplaces including Amazon, Flipkart, Meesho, Tata 1mg and Snapdeal reportedly described the products as “Made in India”, while manufacturer or seller information was incomplete or obscured.
The concern is particularly serious because mercury can be absorbed through the skin. Mercury is sometimes added illegally to skin-lightening products because it interferes with melanin production, producing a faster whitening effect. But the same process exposes users to a toxic heavy metal.
Dr. Surendra VHH, Senior Consultant - Dermatologist, Apollo Hospitals, Bangalore, spoke to HealthandMe about how long-term use of mercury-laced toxic cosmetics can cause harm.
He says, “The quick lightening effect may seem appealing, but it can come at a serious health cost. Mercury suppresses melanin production and may also cause rashes, skin thinning, sensitivity, and lasting pigmentation changes.”
Talking about the extreme side-effects of using these creams, he said that long-term exposure can allow mercury to accumulate in the body, particularly the kidneys. It has been associated with kidney damage, neurological problems and immune-system effects.
He says, “Mercury-laced skin-lightening creams are not harmless beauty products. Repeated use can expose the body to mercury, can get absorbed especially damaged unhealthy which may affect the kidneys and nervous system, causing symptoms such as headaches, weakness, numbness, tremors and changes in mood or memory. The risk is particularly concerning for pregnant women, breastfeeding mothers and children because of its potential impact on neurological development.”
Agreeing with Dr Surendra, Dr Ruben Bhasin Passi, Senior Consultant - Dermatology, CK Birla Hospital, Gurgaon, told also HealthandMe that mercury-infused cosmetics come at a long-term health cost.
Warning about the same, she explained, “Prolonged exposure may damage the skin’s natural protective barrier, cause persistent discolouration, and allow mercury to accumulate in the body, potentially affecting the kidneys and nervous system. No promise of lighter skin is worth exposing yourself to a substance that can silently compromise your health.”
A 2024 study published in Kidney International found a strong association between prolonged use of mercury-containing skin-lightening creams and membranous nephropathy, a kidney disorder in which the filtering units of the kidneys become damaged and leak excessive amounts of protein into urine.
The World Health Organization has also warned that mercury exposure can severely affect the kidneys, brain and nervous system, and says there is no known safe level of exposure to mercury.
CDSCO has advised consumers not to purchase or use Goree Beauty Cream, Chandni Whitening Cream or similarly named products.
The regulator has also reminded consumers that imported cosmetics must have the required registration and that legally marketed products should carry details like the manufacturer's information, manufacturing license, batch number, manufacturing and expiry dates and, for imported cosmetics, a registration number.
The warning comes after Maharashtra authorities separately banned Goree Beauty Cream following testing that found toxic mercury in the product. Officials had also received complaints involving users who developed kidney-related problems after prolonged use.
Cautioning the users, Dr Surendra said, “Consumers should be wary of products without a clear ingredient list, manufacturer details, batch information or regulatory information. Claims such as “instant whitening” or “herbal” do not automatically mean a product is safe. Anyone concerned about mercury exposure should stop using the product and consult a doctor, especially if symptoms such as tremors, swelling or changes in urination occur. Skin care should focus on healthy skin—not changing its natural colour through potentially harmful shortcuts.”
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