An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.

One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.

Slowing Down The Symptoms

Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.

How Was The Research Conducted?

The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.

The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.

Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”

The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.

Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.

The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.

Billy Connolly Parkinson's Disease: Martin Compston, Sottish actor and former footballer praised Sir Billy Connolly, actor, comedian and musician, for handling his Parkinson's disease in an "incredibly brave" way.

The 83-year-old comedian was diagnosed in 2013, and five years post that, in 2018, he announced his retirement. Compston who is also co-host of Hoolie In The Hydro, said that the Scottish comedian battled the disease "with a smile on his face and cracking jokes that only Billy can."

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He said, "Obviously, Billy’s been battling Parkinson’s but he’s been battling incredibly bravely and again he’s done it with a smile on his face and cracking jokes that only Billy can. I’m hoping he’s with us for a long time to come.”

Billy Connolly Health Update

In 2024, Billy made an admission about death amid his ongoing health struggles. In his 2023 autobiography, he mocked the "exaggerated" reports of his "demise". However, the actor-comedian said that he has maintained a positive outlook about his health and that he does not feel "close to death".

In an interview with The Mirror, he said that he remembers the day when he was told he had Parkinson's was the same day he was diagnosed with prostate cancer. "Yes, it was a funny week I had. On the Monday, I had hearing aids. On the Tuesday I got pills for heartburn, which I have to take all the time, and on the Wednesday, I got news that I had prostate cancer and Parkinson’s."

He shared that the best way to deal with such a news is to start thinking about the next step, which is the treatment. "You just have to think. Don't think you are being badly treated [by life] or you have the bad pick of the straws. You are one of millions. Just behave yourself and relax."

Connolly got the all-clear from prostate cancer after receiving treatment, reported the Independent.

Read: Can You Detect Dementia With An Eye Test?

As far as Parkinson's is concerned, his wife, Pamela Stephenson had said that her husband had the "most significant" symptom of the disease, which was a "couple of serious falls" that happened after his balance deteriorated due to Parkinson's.

Talking to Guardian, Billy said, "Recently I've noticed a deterioration in my balance. That was never such a problem before, but in the last year that has come and it has stayed. For some reason, I thought it would go away because a lot of the symptoms have come and gone away."

Prostate Cancer And Parkinson's Disease In Men Aged 40-50

The John Hopkins Medicine recommends screening for prostate cancer at age 55, and start their PSA screening between ages 40 to 54.

What Is Prostate Cancer? Prostate cancer is the most commonly diagnosed cancer in men and the second leading cause of cancer-related deaths in the United States. In many cases, it grows slowly, and detecting or treating it before symptoms appear may not always improve health outcomes or extend life. Learn more about prostate cancer, including screening, prevention, treatment options, research, and key statistics.

The National Institute of Neurological Disorders and Stroke says that while an average age of onset of Parkinson's disease in a person is in early to mid 60s, there could be some people who may have the disease before the age of 50.

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In fact, a 2019 study in the Journal of Parkinson's Disease notes that while the mortality rate of Parkinson's disease is higher in women, risk of developing it is twice as high in men than women.

What Is Parkinson's Disease? Parkinson’s disease is a slowly progressing disorder that affects movement and the nervous system. It develops when certain nerve cells in the brain weaken, become damaged, or die. As a result, people may experience tremors, stiffness, slowed movement, and balance problems. Over time, these symptoms can make everyday activities like walking, talking, and simple tasks more difficult.

Three children from Ottawa and Eastern Ontario have died due to flu-related complications over the past two weeks, as an unusually early and aggressive flu season grips the region. Health officials have confirmed that the cases are linked to Influenza A, a strain currently circulating widely and affecting children more severely than usual, as per CTV news.

The children were between five and nine years old. Authorities have not released further personal details about the two Ottawa cases and one case from Eastern Ontario.

What Is Influenza A?

Influenza A is a fast-spreading respiratory virus responsible for seasonal flu outbreaks and, at times, global pandemics. It changes quickly through genetic shifts, which makes new strains harder to predict and control. The virus is grouped based on surface proteins called hemagglutinin and neuraminidase, with H1N1 and H3N2 among the most common strains in circulation. It spreads mainly through coughs, sneezes, or close contact and often comes on suddenly, causing fever, cough, body pain, and extreme tiredness. In some cases, it can lead to serious complications, especially in vulnerable groups.

Influenza A: Health Officials Call Deaths a Serious Warning

Public health leaders from Ottawa and Eastern Ontario described the deaths as a troubling reminder of how dangerous the flu can be, especially for children.

“This highlights that influenza is not always a mild illness. It can lead to serious complications that require hospitalization,” medical officers of health from both regions said in a joint statement issued on Monday, as per CTV News.

Influenza A: Child Flu Deaths Rare but Not Unprecedented in Canada

While flu-related deaths among children are uncommon in Canada, they are not unheard of. During the last severe flu season in 2022, two children in Ottawa died due to influenza.

Most flu-related deaths in Canada occur among older adults. Of the estimated 3,500 flu deaths reported nationwide each year, roughly 90 percent involve people over the age of 65. However, experts say the current Influenza A strain is behaving differently.

Influenza A Hitting Children Hard This Season

The strain of Influenza A currently circulating has been linked to a sharp rise in severe pediatric flu cases globally. Health officials say the cluster of three child deaths within such a short period, and within a relatively small geographic area, is highly unusual.

This unusual pattern prompted the regional coroner to alert public health authorities after three sudden, unexpected child deaths tested positive for Influenza A.

“It’s rare for the coroner to reach out like this,” said Dr. Trevor Arnason, Ottawa’s medical officer of health. “But this season has been particularly severe.”

Influenza A: Hospitals Strained as Pediatric Cases Rise

CHEO, Ottawa’s children’s hospital, has reported high numbers of children falling seriously ill with the flu since November. Hospitalizations have continued to rise through early December.

Last week, CHEO issued an urgent request asking family doctors to extend clinic hours and assist at the hospital’s Kids Come First clinic to help manage patient volumes.

Hospital officials have also noted that many children arriving at the emergency department with severe flu symptoms had not been vaccinated.

Influenza A: Strong Push for Flu Vaccination as Cases Surge

Public health officials, including Ontario’s Chief Medical Officer of Health Dr. Kieran Moore, are urging everyone aged six months and older to get vaccinated as soon as possible.

Dr. Arnason and Dr. Paul Roumeliotis, medical officer of health and CEO of the Eastern Ontario Health Unit, stressed that vaccination is especially important for children this season.

Influenza A: Vaccine Still Effective Despite Strain Mutation

Some people have expressed concern after reports suggested this year’s flu vaccine is not a perfect match for the circulating Influenza A strain. Health officials clarified that while the virus has mutated slightly since circulating in the southern hemisphere, the vaccine still offers meaningful protection.

“The flu vaccine may not always prevent infection, but it significantly reduces the risk of severe illness, hospitalization, and complications,” officials said. They added that the vaccine takes about two weeks to become fully effective, making early vaccination crucial ahead of the holiday season, when virus spread typically increases.