Is 'Sticky Gunk' In Your Brain The Reason Behind Alzheimer's Disease?

Updated Mar 20, 2025 | 08:53 AM IST

SummaryThe new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years.
Alzheimer's Disease

Credits: Canva

An experimental treatment happens to be the solution to delay Alzheimer's symptoms in some people. These people are the ones who are genetically destined to get the disease in their 40s or 50s. These new findings form ongoing research has now been caught up in Trump administration funding delas. The early results of the study has been published on Wednesday and the participants too are worried that politics could cut their access to a possible lifeline.

One of the participants had said, "It is still a study but it has given me an extension to my life that I never banked on having." The participant is named Jake Henrichs, form New York City, who is 50 years old. He is one of them to be treated in that study for more than a decade now and has remained symptom-free despite inheriting an Alzheimer's-causing gene that had killed his father and brother around the same age.

Slowing Down The Symptoms

Two drugs which can modestly slow down early-stage Alzheimer's are sold in the United States. These drugs clear the brain of one of its hallmarks, a sticky gunk-like part called the amyloid. However, there have not been any hints that removing amyloid far earlier, way many years before the first symptoms appear, may postpone the disease.

How Was The Research Conducted?

The research is led by Washington University in St Louis, which involved families that passed down rare gene mutation as participants. This meant it was almost guaranteed that they will develop symptoms at the same age their affected relatives did.

The new findings is based on a subset of 22 participants who received amyloid-removing drugs the longest, on average eight years. Long-term amyloid removal cut in half their risk of symptom onset. The study is published in the journal Lancet Neurology.

Washington University's Dr Randall Bateman, who directs the Dominantly Inherited Alzheimer's Network of studies involving families with these rare genes says, "What we want to determine over the next five years is how strong is the protection. Will they ever get the symptoms of Alzheimer’s disease if we keep treating them?”

The researchers before though did not know what exactly caused Alzheimer's which affects nearly 7 million Americans, most of them in their later life. However, it is clear that these silent changes occur in the brain at least two decades before the first symptom shows up. The big contributor. At some point amyloid buildup can trigger a protein named tau that then starts to kill neurons, which can lead to cognitive decline.

Researchers are now thus studying the Tau-fighting drugs and are looking into other factors, like inflammation, brain's immune cells and certain virus.

The National Institute of Health (NIH) has expanded its focus as researchers have found more reasons for Alzheimer's. In 2013, the NIH's National Institute on Aging funded 14 trials of possible Alzheimer's drugs over a third targeting amyloid. By last fall, there were 68 drugs and 18% of them target amyloid. However, there are scientists too who think that amyloid is not everything and their is way more in the brain tissue, immune cells, and more which can be studied.

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New Research Challenges The One-Night Sleep Apnea Test Doctors Have Relied On For Decades

Updated Jul 8, 2026 | 04:00 PM IST

SummaryThe diagnosis of Obstructive Sleep Apnea commonly relies on the single-night sleep study, which, according to recent research, could give inaccurate results.
New Research Challenges The One-Night Sleep Apnea Test Doctors Have Relied On For Decades

Credit: AI

The single overnight sleep study, usually conducted to diagnose obstructive sleep apnea (OSA) may not be accurate enough, according to a recent study. Sleep patterns change significantly from one night to the next, meaning current one-night testing could underdiagnose or overestimate the condition in some patients.

The study, published in the journal npj Digital Medicine, challenges the long-standing practice of relying on a single overnight sleep study, also known as polysomnography, to diagnose OSA.

How Was The Study Conducted?

Obstructive sleep apnea is a common sleep disorder in which breathing repeatedly stops and starts during sleep due to blockage of the upper airway. If left untreated, it has been linked to serious health problems, including high blood pressure, cardiovascular disease, type 2 diabetes, stroke, and reduced quality of life.

To investigate whether a single sleep study accurately reflects a person's condition, researchers studied about 100 adults for suspected sleep apnea.

Participants underwent standard overnight polysomnography, a gold-standard diagnostic test. Simultaneously, they also had their sleep monitored repeatedly over several weeks in their home environment.

The researchers then compared the results from the one-night test with the average findings collected across multiple nights.

Read more: Bryan Johnson Battles Autoimmune Gastritis: Which Parts Of His Longevity Guide Are Actually Worth Copying?

Is The Single-Night Sleep Apnea Test Reliable?

The analysis revealed significant night-to-night variation in sleep apnea severity. In many cases, the severity measured during one laboratory night did not match the average severity recorded over multiple nights.

As a result, some patients could get classified into the wrong severity category due to the one-night test, particularly those whose sleep apnea naturally fluctuates or whose sleep is easily affected by the unfamiliar environment.

Lead author Dr Bastien Lechat, a sleep expert at FHMRI Sleep Health, said, “Our findings show that sleep apnea can vary considerably from one night to the next, so if you only measure it once, you may not capture the true severity of the condition. In some participants, we saw clear differences between the single-night result and the average across multiple nights, which suggests current diagnostic approaches may under- or overestimate disease severity in some individuals.”

The researchers also found that patients whose classifications changed between the types of tests often experienced poorer sleep during laboratory testing. This indicated that an unfamiliar sleep environment may alter sleep quality and influence results.

Senior author Professor Sutapa Mukherjee, Professor of Respiratory and Sleep Medicine at Flinders University and Senior Consultant at Southern Adelaide Local Health Network (SALHN), said, “Our findings show that sleep apnea is a dynamic disorder, and by capturing how it changes over time, we can build a much more accurate and clinically meaningful picture of a patient's condition.”

The researchers also believe that monitoring sleep on multiple nights can help doctors assess a patient's future health risks and course of treatment in a better way.

While further research is needed before multi-night monitoring becomes routine clinical practice, the authors believe the study marks an important step toward modernizing sleep apnea diagnosis.

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How This Viral 'Squishy' Toy Left Several Children With Severe Burns? Doctors Issue Warning To Parents

Updated Jul 8, 2026 | 03:00 PM IST

SummaryThe popular NeeDoh Nice Cube and similar squishy toys sparked an alarming number of burn cases in children across the US, UK and Australia due to a viral social media trend.
Viral 'Squishy' Toy Trend Leaves Children With Severe Burns; Doctors Issue Urgent Warning To Parents

Credit: AI

Doctors and health experts across the United States, the United Kingdom and Australia are warning parents about a dangerous social media trend involving gel-filled "squishy" sensory toys, including the popular NeeDoh Nice Cube.

This trend has children microwaving the toys after watching viral online videos that claim it makes them softer. In many cases, the toys exploded, spraying scalding gel that caused severe burns, permanent scarring, and hospitalization in some cases.

The Viral Squishy Toy Trend

The viral challenge got children to microwave, heat or even freeze sensory toys before squeezing them.

The thick gel inside these toys can rapidly build pressure when heated. When the toy bursts, it ejects extremely hot, sticky gel that clings to the skin, making burns deeper and more difficult to treat.

The danger is particularly high as the skin of children is thinner. Additionally, they often hold the toy close to their faces.

Alarming Incidents Across Countries

Several children around the world have suffered serious injuries due to the trend. One of the most widely reported cases was 9-year-old Caleb Chabolla from Illinois, who microwaved a NeeDoh Nice Cube after believing it would become softer.

As he removed it from the microwave, the toy exploded, leaving him with second-degree burns to his face and hands. He was taken to a specialized burn center.

In Australia, 10-year-old Violet Zerbst suffered severe facial burns after microwaving the toy. When she squeezed it, boiling gel splashed across her face. Her father shared the traumatic experience to warn other parents.

Also read: Recurring UTIs In West Bengal Toddler Reveal Rare Metabolic Disorder - Cystinuria; Here's What Parents Should Know

Another recent case involved 7-year-old Livi Barnard in the UK, whose mother says a NeeDoh toy leaked hot liquid onto her hands, causing painful burns and blisters that required repeated hospital dressing changes.

In one case, the toy exploded without being microwaved. In West Virginia, a teenager was burned after a squishy toy that had been left inside a hot car exploded, releasing hot sticky material onto her legs.

Doctors at the Royal Hospital for Children in Glasgow have seen multiple children with similar burn injuries over recent months, with some requiring skin grafts and long-term care.

Doctors Issue Urgent Warning To Parents

Burn specialists say that these injuries are far more serious than they seem. The hot gel sticks to the skin, continuing to transfer heat for a longer time even after the initial explosion.

In severe cases, while children have required skin grafts, some have been placed in medically induced comas to protect their airways after extensive facial burns.

Medical experts are urging parents to:

  • Never allow children to microwave, heat, or freeze squishy toys.

  • Warn children about dangerous viral social media challenges.

  • Keep sensory toys away from hot cars and other high-temperature environments.

  • Seek immediate medical attention if a burn occurs, especially if the gel sticks to the skin or affects the face or eyes.

The manufacturer of NeeDoh, Schylling, has already put warnings on product packaging stating that the toys should never be heated, microwaved, or frozen.

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At 2026 NATO Summit, Trump's Neck Rash and Bruised Hand Draw Attention; White House Responds

Updated Jul 8, 2026 | 02:00 PM IST

SummaryDuring the summit's welcome ceremony, Turkish President Recep Tayyip Erdoğan, 72, was seen taking Trump by the arm and guiding him into position. The White House has continued to insist that the 80-year-old president, the oldest America has ever had, remains in good health.
At 2026 NATO Summit, Trump's Neck Rash and Bruised Hand Draw Attention; White House Responds

Credit: AP Pics

US President Donald Trump was seen with a visible neck rash and a bruised right hand that appeared to be covered with makeup during the 2026 NATO Summit in Türkiye, drawing renewed attention to his health. However, the White House has continued to insist that the 80-year-old president, the oldest America has ever had, remains in good health.

The 2026 NATO Summit was held at the Beştepe Presidential Complex in Ankara, Türkiye, from July 7 to 8.

Trump's Bruised Hand And Neck Rash Spark Attention

The back of Trump's right hand—visible beneath white sleeves fastened with presidential cufflinks—looked noticeably darker than the surrounding skin, suggesting it may have been covered with makeup, The Independent reported.

The recurring discoloration has attracted attention in recent months. Similar bruising, often accompanied by visible cosmetic coverage, has been photographed during Trump's appearance at a UFC event at the White House in June and after a meeting with coal miners in February. Some photographs have also appeared to show similar markings on his left hand.

A neck rash was also visible above the president's shirt collar. Trump additionally appeared unsteady on his feet, particularly while using stairs.

Also read: Donald Trump Posts AI Video of Himself Treating Critics for 'Derangement Syndrome'

Erdoğan Seen Guiding Trump At Welcome Ceremony

During the summit's welcome ceremony, Turkish President Recep Tayyip Erdoğan, 72, was seen taking Trump by the arm and guiding him into position.

Both Trump, 80, and Erdoğan have faced public scrutiny over their physical and cognitive health. Trump has drawn attention for rambling speeches, apparent dozing during public events, and the recurring bruising on his hands. Erdoğan has similarly been the subject of discussion over verbal stumbles, moments of confusion, and a slower walking pace.

White House Dismisses Health Concerns

Read More: New Book Examines Donald Trump's Health, Age Concerns; White House Responds

The White House has repeatedly dismissed concerns, attributing the bruising to the physical demands of Trump's public schedule.

"President Trump is the sharpest, most accessible, and energetic president in American history," White House spokesperson Davis Ingle said in a statement provided to The Independent. "The President is a man of the people and he meets more Americans and shakes their hands on a daily basis than any other President in history."

In February, White House Press Secretary Karoline Leavitt also said the bruising resulted from frequent handshaking.

Following Trump's most recent medical examination in May, White House physician Dr. Sean Barbabella said the bruising was consistent with "minor soft tissue irritation related to frequent handshaking" while the president was taking aspirin as a preventive measure against cardiovascular disease.

After his check-up at Walter Reed, Trump wrote on Truth Social that "everything" had "checked out PERFECTLY."

Public attention has also focused on other aspects of Trump's appearance in recent months. A swelling around his ankles and occasions during official events when he appeared to keep his eyes closed for extended periods have been raising health concerns.

The White House has previously said the ankle swelling is caused by blood pooling in the lower legs, describing it as a common condition among older adults.

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