Smokers who make the decision to quit will experience immediate health benefits, including a rapid reduction in their risk of atrial fibrillation (A-Fib), according to new research published in JACC: Clinical Electrophysiology. The study, conducted by Dr. Gregory Marcus, a cardiologist at the University of California, San Francisco, offers compelling evidence for smokers to quit, showing that it’s never too late to avoid the damaging effects of smoking on heart health.

Dr. Marcus, the senior author of the study, emphasized that A-Fib can be prevented even in individuals who have smoked for years. "The findings provide a compelling new reason to show current smokers that it’s not too late to quit, and that having smoked in the past doesn’t mean you’re ‘destined’ to develop A-Fib," Marcus explained. "Even for the current and longtime smoker, A-Fib can still be avoided."

What is Atrial Fibrillation (A-Fib)?

"There’s strong evidence that smoking increases the risk of A-Fib," Marcus said. "But the benefits of quitting smoking have been less certain." With this in mind, his team sought to determine whether quitting could significantly lower a person’s risk of developing A-Fib, or if the risk would remain the same.

The research team analyzed data from over 146,700 current and former smokers, tracking their smoking habits and health over a 12-year period using data from the UK Biobank database. The results were promising: former smokers had a 13% lower risk of developing A-Fib compared to current smokers, while those who quit during the study saw an 18% reduction in their risk.

"This is likely a testament to the potency of reducing atrial fibrillation risk pretty shortly after quitting," Marcus said in a statement from the American College of Cardiology.

The findings highlight the importance of quitting smoking, not only for general health but specifically for reducing the risk of serious heart conditions like A-Fib.

Tips for Quitting Smoking

Quitting smoking is one of the most effective ways to lower the risk of A-Fib and improve overall heart health. While it can be challenging, the benefits of quitting are clear and immediate. Here are some tips to help you quit smoking successfully:

1. Choose a specific date to quit smoking and stick to it. Prepare yourself mentally and physically for this change.

2. Reach out to family, friends, or a support group to help keep you accountable. Sharing your goals with others can provide encouragement.

3. Options like nicotine patches, gum, or lozenges can help ease withdrawal symptoms and reduce cravings.

4. Identify situations that make you want to smoke, such as stress or social gatherings, and find healthy ways to cope with them.

5. Regular exercise can help distract you from cravings and improve your mood during the quitting process.

6. Drinking water can help flush nicotine out of your system faster, reducing cravings.

7. Activities like yoga, meditation, or deep breathing exercises can help manage stress, a common trigger for smoking.

Quitting smoking offers immediate and significant benefits, particularly in reducing the risk of atrial fibrillation. The latest research provides smokers with more motivation to quit, showing that it's never too late to take control of their heart health.

Philadelphia Eagles quarterback Jalen Hurts is expected to miss the remainder of the 2026 NFL season after being diagnosed with deep vein thrombosis (DVT) and blood clots in both lungs.

In a statement on October 19, the team said the 28-year-old was clinically stable with no significant functional limitations. However, he needs blood thinners and cannot participate in contact sports while taking them.

His diagnosis raises questions about how blood clots travel from the legs to the lungs, why they are dangerous and how to reduce the risk.

What Happened To Jalen Hurts?

Hurts was initially diagnosed with a superficial blood clot in his left calf after reporting discomfort following a cleat injury during the October 4 game against the Los Angeles Rams.

Although doctors initially cleared him to play, a follow-up ultrasound in Philadelphia and further testing identified DVT and blood clots in both lungs, known as bilateral pulmonary emboli.

The team said his treatment would involve anticoagulants, or blood thinners. He can resume football activities once he stops taking the medication.

Also read: Hours Of Sitting, Gaming And Binge-Watching OTT? Doctors Warn Of Blood Clot Risk In Young People

What Is Deep Vein Thrombosis?

Deep vein thrombosis occurs when a blood clot forms in a deep vein, usually in the leg. If part of the clot breaks away and travels to the lungs, it can cause a pulmonary embolism (PE), a potentially life-threatening condition.

Prolonged sitting, hospitalization, bed rest, injuries and certain genetic factors can increase the risk of developing blood clots.

How Can A Leg Clot Travel To The Lungs?

A clot can break away from a deep vein in the leg, travel to the right side of the heart and then enter the arteries supplying the lungs. There, it can block blood flow and strain the heart.

“You have a clot in your leg. The problem is it can travel up the veins and go to your heart, and from there, go to your lungs, and block the blood vessels in your lungs,” CBS News chief medical correspondent Dr. Jon LaPook, who is not treating Hurts, told CBS Mornings.

“That's very serious,” he added.

Why Are Athletes At Risk Of Blood Clots?

Read More: World Thrombosis Day: Can An Unexplained Blood Clot Be The First Sign Of Cancer? Experts Explain

Hurts is not the first high-profile athlete to experience blood clots. Tennis star Serena Williams has a history of clots, while NBA Hall of Famer Chris Bosh retired early following blood-clot-related complications.

Fitness does not eliminate the risk. Injuries and prolonged immobility, including during long-haul flights, can slow blood flow and contribute to clot formation.

DJ Corey, director of Northeastern University’s EMT program, said extended periods of sitting during air or road travel can increase the risk because leg muscles help maintain blood circulation.

The US Centers for Disease Control and Prevention (CDC) also warns that limited mobility during long-distance travel can increase the risk of venous thromboembolism (VTE), which includes DVT and pulmonary embolism.

How Can Travellers Reduce Their Risk?

To improve circulation during long journeys, the CDC recommends:

• Moving the legs frequently while seated.
• Walking periodically when it is safe to do so.
• Avoiding prolonged immobility.
• Consulting a doctor about preventive measures if you have additional risk factors.

Compression stockings may help some travellers at increased risk, depending on their medical needs.

What Are The Warning Signs Of Blood Clots?

DVT symptoms can include leg swelling, pain, tenderness, warmth and skin discoloration. Some people may have no obvious symptoms.

Pulmonary embolism warning signs include sudden breathlessness, chest pain, a rapid heartbeat, lightheadedness and coughing up blood.

Sudden breathing difficulties, chest pain or fainting require immediate medical attention, as a pulmonary embolism can be life-threatening.

More than 20 vials of compounded tirzepatide, a GLP-1 medication containing the same active ingredient as Eli Lilly’s Mounjaro and Zepbound, have been recalled in the US over sterility concerns, according to the Food and Drug Administration (FDA).

The recall, issued by Apothecary Pharma, also includes a vial of NAD+ injection.

The FDA classified the recall as Class II, meaning the affected products could cause temporary or medically reversible adverse health consequences, while the likelihood of serious harm is considered low.

The recall follows a December 2025 FDA warning letter to Apothecary Pharma, which cited serious deficiencies in the North Carolina company’s sterile drug production practices.

The recalled injections are compounded versions of tirzepatide. Unlike FDA-approved, brand-name medications, compounded drugs are custom-prepared by pharmacies to meet specific patient needs.

Which Compounded GLP-1 Injections Were Recalled?

Also read: US FDA May Allow Pharmacies To Make Unapproved Peptide Injections: What Are the Safety Concerns?

The affected tirzepatide product is a prescription injection with a concentration of 18 mg/mL, supplied in a 4 mL multidose vial. Its National Drug Code (NDC) number is 85091-001-18.

The recalled lot numbers are AP-202622 through AP-202625 and AP-202627 through AP-202644. The products have beyond-use dates ranging from October 7 to November 26, 2026.

The recall also includes one vial of NAD+ injection.

What Should You Do If You Have a Recalled Vial?

The FDA and Apothecary Pharma have not issued a public statement clarifying what patients should do with the affected vials. Some customers have reported receiving requests through their prescribers to return or dispose of the products or contact the manufacturer directly.

NewLife Rx, a pharmaceutical fulfillment service that distributed some of the recalled vials, reportedly told certain customers that Apothecary had described the recall as a documentation issue.

According to a notice reviewed by USA TODAY, the recall was conducted at the retail level and did not extend to patients or require them to stop using or return their medications.

However, neither the FDA nor Apothecary Pharma has publicly clarified the reason for the recall or the safety of the affected products.

Although a Class II classification indicates a relatively low likelihood of serious harm, it does not mean a product is entirely risk-free.

If you have an affected lot, consult your prescriber or healthcare provider before using it again and follow their instructions.

Read More: Retatrutide Driving Peptide-Linked Emergency Hospital Admissions In Australia: What Are The Risks?

What Are the Risks of Compounded GLP-1 Drugs?

A compounded drug is a medication prepared by a compounding pharmacy to meet an individual patient's specific medical needs. This may include removing an allergen, adjusting a dosage, or preparing a formulation that is not commercially available.

While these medications can serve specific medical needs, they are not FDA-approved in the same way as branded drugs. The FDA does not review compounded formulations for safety, effectiveness, and quality before they are marketed.

Demand for GLP-1 medications for weight loss skyrocketed worldwide between 2022 and 2025, leading to shortages of semaglutide and tirzepatide.

During these shortages, compounding pharmacies were legally allowed under specific circumstances to prepare several versions of these medications.

Many patients turned to compounded GLP-1s because they were often affordable, available, and easier to buy online.

Potential risks of compounded GLP-1 drugs include:

• Inaccurate Dosing
• Sterility Concerns
• Different Ingredients
• Limited Safety Data
• Counterfeit or Unregulated Products

The US Food and Drug Administration (FDA) has approved Hibsago (bepirovirsen), a first-of-its kind treatment for certain adults with chronic hepatitis B. The drug controlled virus activity in some patients after stopping all treatment.

Announced on October 20, 2026, the approval makes Hibsago the first FDA-approved antisense oligonucleotide for chronic hepatitis B.

It is approved for certain adults without cirrhosis who have already been taking antiviral medication for at least six months, have suppressed levels of hepatitis B virus (HBV) and meet specific criteria for hepatitis B surface antigen (HBsAg).

In clinical trials, 19% of patients receiving Hibsago maintained viral control 24 weeks after stopping all hepatitis B treatment. No amount of HBsAg was detected in their blood. The treatment is meant to offer an alternative for some patients who otherwise need long-term antiviral medication.

“For many people living with chronic hepatitis B, treatment can mean taking antiviral medication for years to keep the virus suppressed,” said Wendy Carter, DO, acting director of the Office of Infectious Diseases in the FDA’s Center for Drug Evaluation and Research.

“Hibsago provides a new treatment approach that gives some patients the possibility of maintaining control of the virus after all chronic HBV treatment has ended. This approval represents an important advance for people living with this serious disease.”

How Does Hibsago Work?

Hibsago targets the genetic aspects the hepatitis B virus targets. By reducing viral RNA and hepatitis B surface antigen, the drug helps the immune system control the infection even after after treatment ends.

The drug is administered as an injection under the skin for up to 24 weeks, alongside a patient's existing hepatitis B medication. Patients continue their treatment for at least 24 weeks after the final Hibsago injection. They can then stop all treatment if they meet specified clinical and laboratory criteria.

The FDA also authorised a diagnostic test to help identify eligible patients and monitor them during treatment.

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What Did The Clinical Trials Find?

The approval was supported by two Phase 3 trials, B-Well 1 and B-Well 2, which compared Hibsago with a placebo in adults receiving established antiviral treatment.

Across the trials, 24% of patients receiving Hibsago met the criteria to stop their existing antiviral medication, compared to none in the placebo groups.

At 24 weeks after stopping all treatment, 19% of patients receiving Hibsago maintained viral control. Hepatitis B surface antigen was also no longer detectable in their blood.

The outcome means the virus remains controlled without ongoing treatment according to specified laboratory criteria.

Also read: H. pylori, HPV Among Five Infections Behind 1 In 8 Cancers Worldwide: Lancet

What Are The Risks?

Hibsago carries a warning for serious liver reactions and thrombocytopenia, or low platelet counts, which can increase the risk of life-threatening bleeding.

Other warnings include poor kidney function and inflammatory reactions like vasculitis. Patients require regular blood tests and medical monitoring before and during treatment.

The FDA granted Hibsago Fast Track and Breakthrough Therapy designations, along with Priority Review. The drug was approved for GSK plc.

The treatment is not suitable for everyone with chronic hepatitis B. Eligibility depends on liver health, existing treatment, viral suppression and laboratory results.