Cigarettes with ultralow nicotine levels are now being called the game-changer in the fight against smoking. If you are having trouble in quitting smoking, then, it is for you, that soon the Biden White House is expected to formally propose a plan that will order cigarette nicotine levels to be reduced, reports The Washington Post. For now though, it has been a failure, as these cigarettes, also known as VLN cigarettes that stands for very low nicotine are only available in 5,100 stores in 26 states. This is a very small fraction of the overall market for cigarettes. The company that makes it, 22nd Century, is struggling not because of the low supply, but also from the advocates who have long believed slashing nicotine levels altogether.

The Advent and ideation

Nicotine is a chemical that is produced naturally from tobacco that makes the cigarette and also keeps people hooked. While it is believed that it makes people alert, and get the "hit" to keep them going, it exposes the users to harmful substances, carcinogens, and increases the risk of heart disease, lung cancer, and other illness.

Ultralow-nicotine cigarettes, like the VLN brand, contain about 95% less nicotine than the regular cigarettes. The idea is quite simple: without the addictive grip of nicotine, smokers will find it easier to quit. Research too has shown some promise. For instance, the studies funded by the National Institute on Drug Abuse revealed that very low nicotine cigarettes reduced addiction potential significantly without having users to increase their smoking frequency. However, the problem is, why would anyone choose for a low-nicotine that does not make them feel the same way, when the high-nicotine cigarette is right next to it, making them feel the same way, with the same alertness, sold at the same price.

“It’s very hard to imagine someone actively choosing to continue to use a low-nicotine product for the same price when a high-nicotine product is right next to it,” said Eric Donny, a Wake Forest University School of Medicine nicotine researcher.

No wonder, the experiment with low nicotine product by Philip Morris' Next cigarettes in the 1980s and Vector Tobacco's Quest brand in the early 2000s, flopped.

FDA's Role in the Push

The Food and Drug Administration (FDA) has supported the development of such products, even allowing VLN cigarettes to be marketed as lower-risk options. However, these products remain a niche market, available in only a fraction of U.S. stores.

Recently, the Biden administration has considered a bold step—mandating a dramatic reduction in nicotine levels for all cigarettes sold in the United States. Supporters believe this move could save millions of lives, while critics, including tobacco companies, warn of potential unintended consequences.

What Could Be The Challenges?

Resistance from Big Tobacco Companies: They could argue that slashing nicotine levels could backfire. Their claim is, smokers will turn to black markets or smoke more to satisfy their cravings, which may lead to greater exposure to harmful substances.

Consumer Reluctance: History is proof to the instances of smokers being hesitant to embrace the low-nicotine products.

Political Hurdle: It may face political roadblocks, as under the Trump administration, plans to cut nicotine were shelved.

Could Low-Nicotine Cigarettes Be The Solution?

Advocates believe that ultralow-nicotine cigarettes could be a game-changer, comparing them to decaf coffee or non-alcoholic beer—products that reduce harm while offering a similar experience.

Some experts warn that a black market for traditional cigarettes could undermine these efforts. They also stress the need for safer alternatives, such as vaping products, to support smokers transitioning away from traditional cigarettes.

Dave Coulier is battling tongue cancer, only months after sharing that he had overcome lymphoma. The “Full House” actor spoke about the diagnosis during an appearance on the “Today” show, describing the news as “a shock to the system.”

The 66-year-old clarified that this illness is “totally unrelated” to his earlier non-Hodgkin’s lymphoma. “This is a new cancer. I said, ‘Are you kidding me?’” he recalled. Doctors told him it may have developed from an HPV infection that could have been present for decades, which later “activated and turned into a carcinoma.”

Despite the shocking news, Coulier said the cancer is “very treatable” and comes with a “90 percent curability rate.” He added that his care team plans to begin radiation right away and that his prognosis is strong.

Dave Coulier Cancer: Dave Coulier Reveals Tongue Cancer Diagnosis

Dave Coulier is navigating another health setback soon after beating stage 3 non-Hodgkin lymphoma. Speaking on Today, the Full House star shared that he has been newly diagnosed with p16 squamous carcinoma, a form of head and neck cancer. He explained that the finding came after a routine visit and PET scan.

“Totally unrelated to the previous cancer that I had,” he said, as per PEOPLE. “So in October of this year, I went in for a PET scan, just a routine check-up, and something lit up on the scan. It turned out that I have p16 squamous carcinoma at the base of my tongue. So I asked the doctors, ‘Did this happen because of the lymphoma?’ And they said, ‘Totally unrelated.’”

What Does Tongue Cancer Look Like?

Tongue cancer can show up as a sore that refuses to heal, a red or white patch (known as erythroplakia or leukoplakia), a lump or area of thickened tissue, or a small growth on the tongue. These changes may come with bleeding that has no clear cause, numbness, pain while swallowing or talking, or a sensation of fullness in the throat. Anyone who notices these issues should speak to a doctor for proper evaluation, as explained by Mayo Clinic.

Tongue cancer develops when cells on the tongue begin growing out of control. Several forms of cancer can affect the tongue, but the most common is squamous cell carcinoma (SCC).

When the front part of the tongue is involved (the part you can see), it is called oral cancer or oral tongue cancer. When it forms on the back of the tongue, deeper in the throat, it is known as oropharyngeal cancer or base-of-tongue cancer. Mayo Clinic notes that this cancer is relatively rare, making up less than 1 per cent of new cases in the United States. Still, it is one of the more frequent head and neck cancers, occurring twice as often in men and most commonly in people aged 40 and above.

Early Symptoms Of Tongue Cancer

Early signs of tongue cancer may include long-lasting sores or ulcers, red or white patches, and a lump or thicker area on the tongue. Other symptoms can include persistent pain, trouble swallowing or speaking, and numbness or tingling inside the mouth.

Tongue Cancer Risk Factors

Researchers have identified several factors that raise the risk of tongue cancer. These are conditions or habits that can increase your likelihood of developing it. The strongest links are heavy smoking and high alcohol intake. The risk becomes much higher when both are present.

Ibuprofen is a commonly available over-the-counter painkiller that you can pick up from nearly any pharmacy or supermarket. Known for its effectiveness, it helps relieve various aches, pains, inflammation, and even symptoms linked to colds, flu, or coronavirus.

However, it’s important to remember that ibuprofen isn’t suitable for everyone. The NHS advises that people in eight key situations should avoid this anti-inflammatory (NSAID) medication, and anyone unsure should check with a pharmacist or doctor.

Ibuprofen Warning: Who Should Avoid It?

The NHS advises the following people should avoid taking ibuprofen:

• Anyone who has had an allergic reaction to ibuprofen, aspirin, or another NSAID
• Those with a stomach ulcer or a history of ulcers
• People with asthma or allergies (such as hay fever)
• Individuals with chickenpox
• Anyone with heart, liver, or kidney problems
• People with blood clotting issues
• Anyone who has previously had a stroke
• Those who are pregnant or trying to conceive

People who have had allergic reactions to ibuprofen, aspirin, or similar NSAIDs like naproxen should avoid it entirely, as should expectant mothers. Those with kidney problems, asthma, or a history of stomach ulcers should always seek medical advice before using ibuprofen, including topical forms.

The NHS adds: “How you take your medicine and the dose you use depends on the type of ibuprofen and how much it contains. Always read the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for guidance if you’re unsure about how to take it or encounter any problems. If a doctor prescribes ibuprofen, follow their instructions carefully.”

Typically, adults can take one or two 200mg ibuprofen tablets or capsules up to three times a day, leaving at least six hours between doses. In some cases, a higher dose may be prescribed, but only under a doctor’s supervision.

Medicines That Require Extra Caution

If you’re taking certain medications, consult a doctor before using ibuprofen. These include:

• Anticoagulants (such as warfarin)
• Steroid medicines
• Antidepressants
• Blood pressure-lowering medicines

The NHS has also noted: “If you’re taking ibuprofen for short-term pain, like a toothache or period pain, you may only need it for a day or two. Long-term conditions, such as rheumatoid arthritis, may require longer courses.”

Who Needs to Consult a Doctor Before Taking Paracetamol?

Paracetamol isn’t suitable for everyone either. The NHS advises that certain groups should get medical guidance before taking it:

• People on certain medications
• Anyone who has had an allergic reaction to paracetamol or another medicine
• Individuals with liver or kidney issues
• People who regularly drink more than the recommended 14 units of alcohol per week
• Those weighing less than 50kg (eight stone) may need a lower dose

Official NHS guidance, as reported by the Mirror, states: “Most people aged 16 and over can take paracetamol. It is also safe during pregnancy and breastfeeding. Paracetamol can take up to an hour to start working and its effects typically last about five hours.”

A weight-loss doctor has issued an urgent alert as people desperate to shed pounds turn to illegal “Godzilla” fat jabs circulating on social media—some of which have been traced back to counterfeit factories and unregulated online sellers. With the party season approaching, pressure grows to look slimmer for family photos, office events and festive gatherings.

Experts warn that this rush is pushing people toward fake versions of retatrutide, a powerful triple-hormone drug still in clinical trials and not approved anywhere in the world. Recent reports from the UK revealed that more than £250,000 worth of counterfeit weight-loss pens labelled as tirzepatide and retatrutide were seized from a covert Northampton factory.

Retatrutide Warning: Experts Flag Rise of Fake Weight-Loss Jabs

Authorities caution that social media has become a “wild west” for buyers chasing dramatic pre-Christmas results. Professor Franklin Joseph, founder of Dr Frank’s Weight Loss Clinic, explains that seasonal pressure combined with unrealistic expectations is driving some toward dangerous, unregulated products. “This is the time of year when people panic."

Professor Joseph said. “They want to show up on Christmas Day or New Year’s Eve looking slimmer, and viral posts convince them there’s a quick fix. But these so-called ‘Godzilla jabs’ being sold online are fake, untested and potentially dangerous.”

What Is A Godzilla Jab?

The term "Godzilla jabs" is a nickname for retatrutide, a potent experimental weight-loss drug still undergoing clinical trials. It is not approved for human use, and regulators have warned against purchasing counterfeit black-market versions.

Retatrutide: Why Are Experts Giving Warning?

Retatrutide, also referred to as the “Godzilla” or “Triple-G” jab due to early trials showing significant weight loss is still strictly experimental. Despite this, counterfeit versions are circulating through online stores, social media channels, Telegram groups and private accounts, often with no medical supervision, no quality control and no legal oversight.

Professor Joseph notes that the festive season makes the risk even greater. “December is a perfect storm,” he said. “People have one event after another, clothes feel tighter, and family members they haven’t seen all year are coming together. Then an influencer tells them they can lose a stone in a month. It’s an illusion—and scammers know exactly how to exploit it.”

Dangers of Fake Retatrutide

Fake jabs may contain:

• Incorrect doses
• No active ingredient at all
• Contaminated mixtures
• Completely different drugs, including insulin, which can trigger dangerous hypoglycaemia

Authorities have repeatedly stressed that buying unlicensed medicines online is not only illegal but can also carry severe health risks. “Most people think the worst that could happen is the jab won’t work,” Professor Joseph said. “But the real danger is what’s actually inside that pen.”

Scientists anticipate that the results from ongoing clinical trials will be available next year, after which they plan to seek formal medical approval. Meanwhile, organised crime groups are increasingly turning to selling illicit medicines online, sometimes as an alternative to traditional street drugs like cocaine. Purchasing these medications without a proper prescription or guidance from a qualified doctor greatly raises the risk of side effects and serious health complications.

Weight-loss injections are carefully tailored to each patient’s body size and medical condition. Taking an excessive or unmonitored dose can be extremely dangerous.