Cigarettes with ultralow nicotine levels are now being called the game-changer in the fight against smoking. If you are having trouble in quitting smoking, then, it is for you, that soon the Biden White House is expected to formally propose a plan that will order cigarette nicotine levels to be reduced, reports The Washington Post. For now though, it has been a failure, as these cigarettes, also known as VLN cigarettes that stands for very low nicotine are only available in 5,100 stores in 26 states. This is a very small fraction of the overall market for cigarettes. The company that makes it, 22nd Century, is struggling not because of the low supply, but also from the advocates who have long believed slashing nicotine levels altogether.

The Advent and ideation

Nicotine is a chemical that is produced naturally from tobacco that makes the cigarette and also keeps people hooked. While it is believed that it makes people alert, and get the "hit" to keep them going, it exposes the users to harmful substances, carcinogens, and increases the risk of heart disease, lung cancer, and other illness.

Ultralow-nicotine cigarettes, like the VLN brand, contain about 95% less nicotine than the regular cigarettes. The idea is quite simple: without the addictive grip of nicotine, smokers will find it easier to quit. Research too has shown some promise. For instance, the studies funded by the National Institute on Drug Abuse revealed that very low nicotine cigarettes reduced addiction potential significantly without having users to increase their smoking frequency. However, the problem is, why would anyone choose for a low-nicotine that does not make them feel the same way, when the high-nicotine cigarette is right next to it, making them feel the same way, with the same alertness, sold at the same price.

“It’s very hard to imagine someone actively choosing to continue to use a low-nicotine product for the same price when a high-nicotine product is right next to it,” said Eric Donny, a Wake Forest University School of Medicine nicotine researcher.

No wonder, the experiment with low nicotine product by Philip Morris' Next cigarettes in the 1980s and Vector Tobacco's Quest brand in the early 2000s, flopped.

FDA's Role in the Push

The Food and Drug Administration (FDA) has supported the development of such products, even allowing VLN cigarettes to be marketed as lower-risk options. However, these products remain a niche market, available in only a fraction of U.S. stores.

Recently, the Biden administration has considered a bold step—mandating a dramatic reduction in nicotine levels for all cigarettes sold in the United States. Supporters believe this move could save millions of lives, while critics, including tobacco companies, warn of potential unintended consequences.

What Could Be The Challenges?

Resistance from Big Tobacco Companies: They could argue that slashing nicotine levels could backfire. Their claim is, smokers will turn to black markets or smoke more to satisfy their cravings, which may lead to greater exposure to harmful substances.

Consumer Reluctance: History is proof to the instances of smokers being hesitant to embrace the low-nicotine products.

Political Hurdle: It may face political roadblocks, as under the Trump administration, plans to cut nicotine were shelved.

Could Low-Nicotine Cigarettes Be The Solution?

Advocates believe that ultralow-nicotine cigarettes could be a game-changer, comparing them to decaf coffee or non-alcoholic beer—products that reduce harm while offering a similar experience.

Some experts warn that a black market for traditional cigarettes could undermine these efforts. They also stress the need for safer alternatives, such as vaping products, to support smokers transitioning away from traditional cigarettes.

Actress Pamela Anderson has opened up about her hepatitis C diagnosis that once made her fear she had only a few years to live, highlighting how dramatically treatment for the viral infection has changed.

Speaking at the 2026 amfAR Gala Venezia during the Venice Film Festival, Anderson recalled being diagnosed with hepatitis C in 2002. She said doctors had told her she had around 10 years to live, describing the diagnosis as a “death sentence”.

Anderson has previously said she contracted hepatitis C after sharing a tattoo needle with her then-husband Tommy Lee. At the time, the diagnosis carried significant uncertainty because effective curative treatments were not yet available. But more than a decade later, Anderson announced that she had been cured of hepatitis C following antiviral treatment.

What Is Hepatitis C?

While some people clear the virus on their own, most people with hepatitis C who do not clear it develop chronic infection. Over time, chronic hepatitis C can cause liver cirrhosis, liver failure and liver cancer.

According to the World Health Organization (WHO), an estimated 47 million people were living with chronic hepatitis C globally, with about 0.9 million new infections occurring each year.

In 2024, approximately 239,000 people died from hepatitis C, mainly due to cirrhosis and liver cancer.

Also read: The Silent Killer: Why More Indians Need To Pay Attention To Liver Cancer

How Did Hepatitis C Become Curable?

The major breakthrough came with the development of direct-acting antivirals (DAAs). Before these medicines became available, hepatitis C treatment relied heavily on interferon-based therapies, which could involve prolonged treatment and significant side effects and did not cure everyone.

The first interferon-free DAA treatments were approved in 2013 and 2014, marking a major turning point in hepatitis C treatment. WHO says these medicines can cure the infection in more than 95% of people, generally within a short course of treatment.

Unlike older treatments, DAAs directly target the hepatitis C virus and prevent it from multiplying. Treatment is now usually oral, much better tolerated and considerably shorter than earlier regimens.

WHO recommends pan-genotypic DAAs for people with chronic hepatitis C, with treatment generally lasting around 12 to 24 weeks depending on the person's condition.

Also read: RFK Jr. Accepts Pennsylvania Child’s Measles Death After Questioning It: Here's Why

Access Remains A Challenge

The transformation in treatment does not mean hepatitis C has disappeared. There is currently no vaccine against hepatitis C, and millions of people remain undiagnosed.

WHO estimates that by the end of 2024, only around 36% of people who had ever been infected knew their diagnosis, while only about 20% of those diagnosed with chronic infection had received DAA treatment. This makes early testing and access to treatment critical.

Anderson's experience also reflects how quickly medicine can change the outlook of a disease. “I’m not a victim, I’m a victor,” Anderson said while accepting the amfAR Award of Courage in Venice.

Just days after questioning whether the state had correctly linked the deaths of two unvaccinated people to the ongoing measles outbreak, US Health and Human Services Secretary Robert F. Kennedy Jr. has acknowledged and accepted that measles caused the death of a six-week-old child in Pennsylvania.

The shift came after Lancaster County Coroner Stephen Diamantoni confirmed that the infant had died from measles. The child was among two people reported by Pennsylvania health officials as having died in connection with the outbreak.

Kennedy had previously questioned the state's reporting and reportedly asked the Centers for Disease Control and Prevention (CDC) to remove the two deaths from its official tally. The CDC subsequently excluded them from its public data while the deaths remained under review.

What Did The Coroner Find?

The case of the six-week-old infant became particularly controversial because initial findings appeared to raise questions about whether measles was the direct cause of death.

According to Coroner Diamantoni, a review of the infant's medical records and clinical information showed that measles was the cause of death. The child had also been diagnosed with a rare congenital condition that made the infant particularly vulnerable to infections.

The other reported death remains more complicated. In that case, a forensic pathologist found that the infant died from a ruptured spleen and did not determine that measles was the cause, although measles was present. Diamantoni also said that the immediate cause of death was a ruptured spleen, which had further complicated the debate.

The coroner had said that he did not believe measles was the cause of death, although measles was listed on the baby's death certificate as a contributing condition.

Also read: Another Child Dies From Measles In US Amid Vaccine Concerns: Why The Virus Is More Than A Fever And Rash

Kennedy Says Shapiro 'Politicized' The Death

Kennedy's acknowledgement of the infant's death comes amid a public dispute with Pennsylvania Governor Josh Shapiro.

Shapiro had criticised Kennedy after the federal health secretary questioned the state's reporting of the deaths, arguing that such statements could undermine confidence in vaccination and public health efforts.

Kennedy, meanwhile, accused Shapiro of “hastily politicizing” the deaths and argued that the state had announced them before the investigations were complete.

The dispute has now placed the focus not only on the deaths but also on how measles fatalities are investigated and recorded by state and federal health authorities.

Also read: Why Has CDC Challenged The Report Of Two Measles Deaths In Pennsylvania?

Pennsylvania's Measles Outbreak Continues

Pennsylvania has been dealing with a major measles outbreak, with hundreds of cases reported and dozens of people hospitalised. State health officials have said the two people who died were unvaccinated.

The controversy comes at a time when measles is resurging in parts of the US, with declining vaccination coverage raising concerns among public health experts.

Measles is highly contagious and can lead to serious complications, particularly in infants and people with weakened immune systems. Vaccination remains the primary method of preventing infection and transmission.

An infected person can spread the virus to around nine out of 10 unvaccinated people who are exposed. Most people recover, but measles can cause serious complications including pneumonia, brain inflammation and death.

The US Department of Health and Human Services (HHS) has terminated 16 grants worth a combined $38 million, including programmes focused on maternal and infant health, postpartum care and infant mortality, as the agency shifts funding priorities towards infertility and physical activity.

The grants, administered through HHS’ Office of Minority Health (OMH), were cancelled on August 25, according to reports. The affected programmes had already received funding for the first two years of their four-year grants.

The move has sparked criticism, particularly because some of the cancelled programmes were directly focused on supporting mothers and babies after childbirth.

HHS Shifts Focus To Infertility And Male Reproductive Health

According to the letters sent to grantees, future awards should directly support efforts aimed at “reducing overmedicalization in health care by addressing the root causes of infertility.”

The areas listed by HHS include hormonal imbalances, endometriosis, uterine fibroids, low sperm count, low testosterone levels and erectile dysfunction (ED). Programmes promoting “regular physical activity and exercise” were also listed among the priorities.

For grants dealing with maternal health, officials reportedly acknowledged that maternal and infant health remained important but said the specific projects did not advance minority health within OMH’s current priority are.

Also read: This Common Heart Attack Risk Starts Silently In Healthy People In Their 20s

Which Health Programmes Lost Funding?

Among the affected programmes was an initiative by Illuminate Colorado, which sends nurses to the homes of minority women following childbirth to check on the health of mothers and newborns.

“It was news to us that maternal and infant fatality prevention wasn’t a priority,” Jillian Fabricius, co-executive director of the organisation, told NOTUS.

Another programme administered by Housing Works and EngageWell helped people with hypertension monitor their blood pressure at home and provided fresh produce and eggs to 150 New Yorkers every two weeks.

The cancelled grants also included programmes focused on cancer screenings, suicide prevention among first responders and reducing obesity among Native American youth.

At the University of Arkansas for Medical Sciences, a programme aimed at reducing maternal and infant mortality among Black families in the Arkansas Delta could also end because of the funding loss.

Leslie Taylor, a university spokesperson, said the issue was “certainly a big issue in our state” given Arkansas’ high maternal and infant mortality rates.

Also read: Why You Suddenly Can’t Tolerate Foods You Once Ate Easily

HHS Decision Is Drawing Criticism

The cancellations come amid a bigger shift in US federal health policy under the Trump administration, with HHS increasingly emphasising infertility, chronic disease prevention, exercise and what officials describe as addressing the underlying causes of health problems.

However, critics argue that programmes addressing maternal and infant mortality are also essential preventive healthcare, particularly for minority communities that experience significant health disparities.

“It is shocking that OMH under any leadership would prioritize erectile dysfunction over the health and wellbeing of infants and new mothers,” Representative Diana DeGette, the ranking Democrat on the House Energy and Commerce health subcommittee, wrote to HHS officials.