Cigarettes with ultralow nicotine levels are now being called the game-changer in the fight against smoking. If you are having trouble in quitting smoking, then, it is for you, that soon the Biden White House is expected to formally propose a plan that will order cigarette nicotine levels to be reduced, reports The Washington Post. For now though, it has been a failure, as these cigarettes, also known as VLN cigarettes that stands for very low nicotine are only available in 5,100 stores in 26 states. This is a very small fraction of the overall market for cigarettes. The company that makes it, 22nd Century, is struggling not because of the low supply, but also from the advocates who have long believed slashing nicotine levels altogether.
Nicotine is a chemical that is produced naturally from tobacco that makes the cigarette and also keeps people hooked. While it is believed that it makes people alert, and get the "hit" to keep them going, it exposes the users to harmful substances, carcinogens, and increases the risk of heart disease, lung cancer, and other illness.
Ultralow-nicotine cigarettes, like the VLN brand, contain about 95% less nicotine than the regular cigarettes. The idea is quite simple: without the addictive grip of nicotine, smokers will find it easier to quit. Research too has shown some promise. For instance, the studies funded by the National Institute on Drug Abuse revealed that very low nicotine cigarettes reduced addiction potential significantly without having users to increase their smoking frequency. However, the problem is, why would anyone choose for a low-nicotine that does not make them feel the same way, when the high-nicotine cigarette is right next to it, making them feel the same way, with the same alertness, sold at the same price.
“It’s very hard to imagine someone actively choosing to continue to use a low-nicotine product for the same price when a high-nicotine product is right next to it,” said Eric Donny, a Wake Forest University School of Medicine nicotine researcher.
No wonder, the experiment with low nicotine product by Philip Morris' Next cigarettes in the 1980s and Vector Tobacco's Quest brand in the early 2000s, flopped.
The Food and Drug Administration (FDA) has supported the development of such products, even allowing VLN cigarettes to be marketed as lower-risk options. However, these products remain a niche market, available in only a fraction of U.S. stores.
Recently, the Biden administration has considered a bold step—mandating a dramatic reduction in nicotine levels for all cigarettes sold in the United States. Supporters believe this move could save millions of lives, while critics, including tobacco companies, warn of potential unintended consequences.
Resistance from Big Tobacco Companies: They could argue that slashing nicotine levels could backfire. Their claim is, smokers will turn to black markets or smoke more to satisfy their cravings, which may lead to greater exposure to harmful substances.
Consumer Reluctance: History is proof to the instances of smokers being hesitant to embrace the low-nicotine products.
Political Hurdle: It may face political roadblocks, as under the Trump administration, plans to cut nicotine were shelved.
Advocates believe that ultralow-nicotine cigarettes could be a game-changer, comparing them to decaf coffee or non-alcoholic beer—products that reduce harm while offering a similar experience.
Some experts warn that a black market for traditional cigarettes could undermine these efforts. They also stress the need for safer alternatives, such as vaping products, to support smokers transitioning away from traditional cigarettes.
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Europe is enduring an unprecedented June heatwave, with temperatures reaching as high as 43.8°C and several countries breaking national records. The extreme weather has forced authorities to issue red alerts, restrict public activities, deploy cooling centers, limit alcohol sales and warn of worsening health risks.
France has been among the worst-hit countries. On June 24, it recorded its hottest day on record, with an average national temperature of 30.0°C, surpassing previous records set in July 2019 and August 2003, according to Météo-France. Temperatures peaked at 43.8°C in the western town of Pulluau, while overnight temperatures also set a new national record.
A record 58 French departments were placed under the highest-level red alert as officials warned of an elevated risk of forest fires amid worsening drought conditions. Forty people reportedly died in drowning accidents during the intense heat, UN News reported.
Spain also recorded its hottest June days on record on June 23 and 24, with temperatures exceeding 40°C in several locations.
In the UK, the Met Office issued a red extreme heat warning and reported a provisional June record of 36.1°C at Gosport in southern England.
Germany issued widespread red alerts, including for Bonn, Frankfurt and Cologne, while Swiss cities such as Geneva, Basel and Zurich were also placed under red alert.
Also read: Heatwave Linked To 212 Deaths In Spain: How Does Heat Impact Health?
According to the World Meteorological Organization (WMO), the heatwave is expected to spread across Western, Central and Southern Europe over the next two weeks. The agency said temperatures are forecast to remain between 3°C and 10°C above average, with daily highs exceeding 35°C across many areas and locally crossing 40°C.
The WMO also warned of more frequent "tropical nights," when temperatures remain above 20°C overnight, preventing the body from recovering from daytime heat.
The worsening conditions have disrupted healthcare services, with media reports saying hospitals have had to postpone critical imaging scans after sensitive equipment overheated. Cities have also opened emergency cooling centers to protect vulnerable residents.
In Paris, authorities have announced temporary bans on public alcohol consumption and takeaway alcohol sales to ease pressure on hospitals. Public drinking will be prohibited from noon to 7 a.m. over the weekend, while takeaway alcohol sales will be banned between 6 p.m. and 7 a.m. Licensed bars and restaurants are exempt.
French Prime Minister Sébastien Lecornu said the country's highest health alert level had been activated to boost hospital staffing and protect vulnerable people.
"We are reaching a saturation point in hospital facilities," said Paris police chief Patrice Faure, while speaking to local media.
Faure has also asked organizers of the Pride march and the Solidays music festival to cancel their events because of the continuing heatwave.
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The extreme temperatures have also reached the sporting world. Formula 1's governing body, the FIA, has declared another "heat hazard" ahead of the Austrian Grand Prix weekend at Spielberg's Red Bull Ring, triggering additional measures to protect drivers, teams and spectators.
"Europe's savage heatwave has the fingerprints of the climate crisis all over it", said United Nations climate chief Simon Stiell. He has called for "a faster shift to renewables, protecting forests and boosting climate resilience".
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The Ebola outbreak in the Democratic Republic of Congo continues to worsen, with cases rising to 1,155 and deaths climbing to 304, as per the latest government data.
The figures represent the total confirmed cases as of June 24, according to a situation report which documented 37 new cases and five new deaths in the previous 24 hours. Ituri, North Kivu and South Kivu remain the most affected provinces in Congo.
Also read: Ebola Outbreak: The Unique Symptoms Seen In Patients Infected With Bundibugyo
The US is now providing doses of an experimental Ebola treatment developed by Mapp Biopharmaceutical for clinical trials in Congo.
The experimental therapy, known as MBP134, was developed by San Diego-based Mapp Biopharmaceutical. While the US had previously kept its stockpile for potential use in exposed American citizens, it is now making doses available to support clinical research in Congo. This is the first time Washington has publicly committed stockpiled supplies of the treatment for a broader international trial.
According to the World Health Organization, researchers will test MBP134 both on its own and alongside the antiviral drug remdesivir, marketed as Veklury. Remdesivir became widely known during the COVID-19 pandemic and is being evaluated to see whether it can improve outcomes when combined with the antibody treatment.
The ongoing outbreak is being driven by the rare Bundibugyo strain, for which no approved vaccine or treatment exists. However, scientists racing to develop vaccines and therapies are hampered by the lack of a viable sample of the virus.
“There’s nothing like having the authentic isolate,” said Thomas Geisbert, Professor of microbiology and immunology at the University of Texas Medical Branch in Galveston, who helped develop previous Ebola vaccines, Bloomberg reported.
“Despite so many cases, the global scientific community has not obtained a clinical sample to isolate the virus for the needed animal challenge studies,” added Jennifer Serwanga, head of immunology at the Uganda Virus Research Institute, the report said.
Further, as per a new WHO modelling study published in The Lancet, the growing Congo Ebola outbreak, which has already spread to Uganda, has a 70 per cent chance of reaching South Sudan soon.
The study combined epidemic modelling with spillover estimation to quantify regional risks associated with the 2026 Ituri outbreak using laboratory-confirmed case data from WHO Situation Reports (33 cases as of May 18, 2026, to 598 cases as of June 8, 2026), with projections extending 12 weeks from May 18 to Aug. 10, 2026. It also integrates operational preparedness considerations relevant for neighboring countries.
The report showed that even with the intensified response within DR Congo, uncertainty remains around reported case numbers due to the low rate of contact tracing.
“Sustained control nonetheless remains the primary determinant of regional risk: importation into Uganda is already established, and South Sudan must continue to reinforce infection prevention and control, rapid response capacity, and cross-border surveillance under International Health Regulations 2005,” said researchers from the WHO Regional Office for Africa, Nairobi, Kenya.
The report called for:
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The United States is now providing doses of an experimental Ebola treatment developed by Mapp Biopharmaceutical for clinical trials in the Democratic Republic of Congo, where a growing outbreak of the Bundibugyo strain has infected more than 1,000 people and claimed over 250 lives. The decision marks a significant shift from the U.S. government's earlier stance, which limited access to the drug to Americans considered at high risk of exposure.
Health officials are racing to find effective ways to contain the outbreak, as there are currently no approved vaccines or treatments specifically designed for the Bundibugyo strain of Ebola. A small number of cases and deaths have also been reported in neighboring Uganda, raising concerns about the disease spreading further across the region.
The experimental therapy, known as MBP134, was developed by San Diego-based Mapp Biopharmaceutical. While the U.S. had previously kept its stockpile for potential use in exposed American citizens, it is now making doses available to support clinical research in Congo. This is the first time Washington has publicly committed stockpiled supplies of the treatment for a broader international trial.
According to the World Health Organization, researchers will test MBP134 both on its own and alongside the antiviral drug remdesivir, marketed as Veklury. Remdesivir became widely known during the COVID-19 pandemic and is being evaluated to see whether it can improve outcomes when combined with the antibody treatment.
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The confirmed cases in the Ebola outbreak in the Democratic Republic of Congo (DRC) have reached the highest total ever recorded during the first month of an outbreak in Africa, according to the World Health Organization (WHO).
As of June 22, confirmed Ebola cases in Congo had risen to 1,094 and deaths to 277, according to the DRC Ministry of Health. The WHO raised concerns about the rapid spread of the deadly virus and the challenges facing containment efforts.
“This is the largest number of confirmed cases in the first month of an Ebola disease outbreak in Africa,” said Dr Abdirahman Mahamud, Director, Health Emergency Alert and Response Operations at WHO, during a press briefing in Geneva.
"What is important is we need to scale up and this outbreak is moving faster than us," he told reporters after returning from Bunia last week.
Mahamud also noted signs of hope, highlighting a quick increase in the number of Ebola beds to over 500 in the past fortnight and signs that community resistance and violent resistance to Ebola responders was beginning to abate.
As of June 24, Uganda had recorded 20 confirmed Ebola cases, including two fatalities. The latest infection was identified on June 21, with no additional cases reported afterward. Of the confirmed infections, 15 were linked to travel from the Democratic Republic of the Congo (DRC), while five resulted from local transmission. Among the nine cases with available location data, eight were detected in Kampala and one in the neighboring Wakiso District.
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