Having Trouble Quitting Smoking? Cigarettes With Low Nicotine Levels Could Be The Solution

Updated Jan 15, 2025 | 09:01 AM IST

SummaryNicotine is a chemical that is produced naturally from tobacco that makes the cigarette and also keeps people hooked. While it is believed that it makes people alert, and get the "hit" to keep them going, it exposes the users to harmful substances, carcinogens, and increases the risk of heart disease, lung cancer, and other illness.
Low-nicotine level of cigarettes

Cigarettes with ultralow nicotine levels are now being called the game-changer in the fight against smoking. If you are having trouble in quitting smoking, then, it is for you, that soon the Biden White House is expected to formally propose a plan that will order cigarette nicotine levels to be reduced, reports The Washington Post. For now though, it has been a failure, as these cigarettes, also known as VLN cigarettes that stands for very low nicotine are only available in 5,100 stores in 26 states. This is a very small fraction of the overall market for cigarettes. The company that makes it, 22nd Century, is struggling not because of the low supply, but also from the advocates who have long believed slashing nicotine levels altogether.

The Advent and ideation

Nicotine is a chemical that is produced naturally from tobacco that makes the cigarette and also keeps people hooked. While it is believed that it makes people alert, and get the "hit" to keep them going, it exposes the users to harmful substances, carcinogens, and increases the risk of heart disease, lung cancer, and other illness.

Ultralow-nicotine cigarettes, like the VLN brand, contain about 95% less nicotine than the regular cigarettes. The idea is quite simple: without the addictive grip of nicotine, smokers will find it easier to quit. Research too has shown some promise. For instance, the studies funded by the National Institute on Drug Abuse revealed that very low nicotine cigarettes reduced addiction potential significantly without having users to increase their smoking frequency. However, the problem is, why would anyone choose for a low-nicotine that does not make them feel the same way, when the high-nicotine cigarette is right next to it, making them feel the same way, with the same alertness, sold at the same price.

“It’s very hard to imagine someone actively choosing to continue to use a low-nicotine product for the same price when a high-nicotine product is right next to it,” said Eric Donny, a Wake Forest University School of Medicine nicotine researcher.

No wonder, the experiment with low nicotine product by Philip Morris' Next cigarettes in the 1980s and Vector Tobacco's Quest brand in the early 2000s, flopped.

FDA's Role in the Push

The Food and Drug Administration (FDA) has supported the development of such products, even allowing VLN cigarettes to be marketed as lower-risk options. However, these products remain a niche market, available in only a fraction of U.S. stores.

Recently, the Biden administration has considered a bold step—mandating a dramatic reduction in nicotine levels for all cigarettes sold in the United States. Supporters believe this move could save millions of lives, while critics, including tobacco companies, warn of potential unintended consequences.

What Could Be The Challenges?

Resistance from Big Tobacco Companies: They could argue that slashing nicotine levels could backfire. Their claim is, smokers will turn to black markets or smoke more to satisfy their cravings, which may lead to greater exposure to harmful substances.

Consumer Reluctance: History is proof to the instances of smokers being hesitant to embrace the low-nicotine products.

Political Hurdle: It may face political roadblocks, as under the Trump administration, plans to cut nicotine were shelved.

Could Low-Nicotine Cigarettes Be The Solution?

Advocates believe that ultralow-nicotine cigarettes could be a game-changer, comparing them to decaf coffee or non-alcoholic beer—products that reduce harm while offering a similar experience.

Some experts warn that a black market for traditional cigarettes could undermine these efforts. They also stress the need for safer alternatives, such as vaping products, to support smokers transitioning away from traditional cigarettes.

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Ozempic/Wegovy Vs Zepbound/Mounjaro: Which Weight Loss Drug Is More Likely To Cause Hair Loss? Study Finds

Updated Aug 19, 2026 | 07:00 PM IST

SummaryA recent study compared effects of Ozempic, Wegovy, Zepbound and Mounjaro to understand which GLP-1 medication caused the maximum amount of hair loss.
Ozempic Vs Zepbound: Which Weight Loss Drug Is More Likely To Cause Hair Loss? New Study Finds

Credit: AI

Hair loss is one of the recent and increasingly discussed concerns among people taking popular weight-loss medicines like Ozempic and Zepbound.

A new study has compared hair loss risk linked with these two drugs to obtain a clear picture of whether one drug is more likely to trigger shedding than the other.

The study, published in the Journal of the American Academy of Dermatology, examined the risk of new-onset hair loss among people taking semaglutide or tirzepatide, the active ingredients in Ozempic/Wegovy and Zepbound/Mounjaro, respectively.

The findings emerge at a time when hair loss due to GLP-1 treatment is widely discussed. Even though the findings indicate, the absolute risk of hair loss due to GLP-1 remains relatively low.

Ozempic Vs Zepbound: Which Drug Poses Higher Risk?

The study compared people who were prescribed semaglutide and tirzepatide and looked at newly diagnosed hair loss. The researchers found an association between use of both medications and hair loss, including conditions like telogen effluvium, a form of temporary shedding that can occur after a major physical or metabolic stress.

However, the researchers say that the findings not be interpreted as proof that either drug directly damages hair follicles. The study was based on electronic health data, which helped researchers identify an association but could not establish that the medication itself was the cause of hair loss.

Also read: Nestlé Customizes Drinks For Ozempic, Wegovy Consumers: What Are Protein And Nutrition Needs of GLP-1 Users?

Why Can Weight-Loss Drugs Cause Hair Shedding?

One of the leading explanations suggests that the hair loss has more to do with the rapid change in metabolic health which helps with the weight loss. Researchers have not found evidence that the drug directly attacks the hair follicles.

When the body undergoes a sudden metabolic change, more hair follicles can prematurely enter the resting phase of the hair-growth cycle. Several months later, those hairs can shed. This effect is known as telogen effluvium.

Reduced food intake can also mean some people consume less protein, iron and other nutrients which are essential for for healthy hair growth. These factors could contribute to shedding during a phase of major weight loss.

Previous clinical data have reported hair loss in around 3% of adults taking Wegovy compared with 1% taking placebo, while Zepbound trials reported hair loss in about 4%-5% of users compared with 1% with placebo.

Also read: Paris Jackson Undergoes ‘Painful’ ECT for Depression: Can Electroconvulsive Therapy Reduce Suicide Risk?

Temporary Hair Loss Due To Metabolic Shift

Telogen effluvium is generally a temporary form of hair shedding. Hair follicles remain intact, meaning they can return to their normal growth cycle once the rapid weight loss stabilises.

Hair shedding may become noticeable several months after weight loss begins, rather than immediately after starting the medication. Regrowth can then take several additional months.

However, not every case of hair loss during GLP-1 treatment is necessarily telogen effluvium. Other forms of alopecia can have different causes and require different treatment.

The new findings come amid growing scrutiny of hair loss as a potential adverse effect of GLP-1 medicines.

A separate large study published in The BMJ in July 2026 also found that adults with type 2 diabetes taking GLP-1 receptor agonists had a slightly higher risk of alopecia compared with people taking other diabetes medicines.

Researchers have stressed that more research is needed to understand whether the medicines themselves contribute to hair loss or whether the shedding is related to rapid weight loss and metabolic or nutritional changes.

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Human H1N2v Swine Flu Case Detected In China: Should You Worry?

Updated Aug 19, 2026 | 04:50 PM IST

Summary​H1N2v differs from seasonal human H1N2 influenza. The “v” stands for variant, indicating a virus of swine origin. According to the US CDC, illness caused by variant influenza viruses has generally been mild, with symptoms similar to seasonal flu.
Human H1N2v Swine Flu Case Reported In China: Should You Worry?

Credit: iStock

China has reported a rare human case of H1N2v swine flu, underscoring the risk of zoonotic transmission and the importance of continued surveillance of swine-origin influenza viruses.

Swine flu is caused by type A influenza viruses that mainly infect pigs. Human infections are rare and usually occur after close contact with infected pigs. When these viruses infect humans, they are known as variant viruses.

H1N2v differs from seasonal human H1N2 influenza. The “v” stands for variant, indicating a virus of swine origin.

China Reports Human H1N2v Case

China reported its first human H1N2v infection in a 2-year-old boy from Yunnan province.

China notified WHO on February 3, 2026, after the infection was laboratory-confirmed on February 2. The child developed mild illness on January 20 and had reported exposure to domestic pigs before becoming ill.

A study by Chinese CDC researchers, published in Frontiers in Public Health on July 29, found:

  • The boy lived near pigs, chickens and pigeons.
  • A pig owned by his great-uncle died around the time the child became ill.
  • Influenza A was detected in samples from the child and the deceased pig.
  • Investigators considered the pig a plausible source, although the exact transmission route could not be established.
  • 30 close contacts were monitored; none tested positive or developed influenza-like illness.
  • No secondary infections were identified, with no evidence of human-to-human transmission.

No Evidence Of Sustained Human Spread

Dr Amit Prakash Singh, Consultant – Internal Medicine at CK Birla Hospital, Delhi, told HealthandMe that H1N2v is a swine-origin influenza virus that can occasionally infect humans, usually after exposure to infected pigs or contaminated environments.

“As no secondary cases or sustained human-to-human transmission were identified, this should not currently be viewed as a pandemic threat,” he said.

People with frequent pig exposure, young children, older adults, pregnant women and those with underlying health conditions may need greater caution, he added.

Prevention includes avoiding close contact with sick animals, practicing hand hygiene and respiratory precautions, and seeking medical attention for persistent or severe flu-like symptoms.

Previous H1N2v Cases

H1N2v infections have been reported sporadically in the US and Europe, particularly following exposure to pigs.

  • CDC surveillance lists 44 confirmed H1N2v infections in the US since 2010 through May 2026.
  • During the 2024–25 influenza season, one H1N2v infection was reported in an adult from Iowa. The patient was hospitalized and recovered.
  • CDC reported two H1N2v infections during the 2025–26 season by May 2026.

Human H1N2v infections remain rare. Greater concern would arise if there were evidence of sustained person-to-person transmission or changes that allow the virus to spread more efficiently among humans.

H1N2v Symptoms

According to the US CDC, illness caused by variant influenza viruses has generally been mild, with symptoms similar to seasonal flu. These can include:

  • Fever
  • Tiredness
  • Loss of appetite
  • Cough
  • Runny nose
  • Sore throat
  • Eye irritation
  • Nausea
  • Vomiting
  • Diarrhea

However, serious illness requiring hospitalization and, in some cases, resulting in death has also been reported.

How Is H1N2v Diagnosed And Treated?

Variant influenza A infection can be diagnosed through respiratory testing. Four antiviral drugs are recommended in the US for treating influenza: oseltamivir, peramivir, zanamivir and baloxavir, the CDC said.

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Harvard Agrees To Pay 53 Million Settlement After Former Morgue Manager Stole And Sold Donated Body Parts

Updated Aug 19, 2026 | 06:00 PM IST

SummaryThe civil lawsuit against Harvard University concerning theft and sale of parts from bodies donated for education and research is about to come to an end after the institution agreed to pay $53 million settlement.
Harvard Agrees To Pay $53 Million Settlement After Former Morgue Manager Stole And Sold Donated Body Parts

Credit: AI

Harvard University has agreed to pay $53 million (Rs 507 crore) to settle lawsuits brought by families whose loved ones donated their bodies to Harvard Medical School for education and research, only to have parts of those remains stolen and sold.

The settlement stems from Cedric Lodge's acts, the former morgue manager of Harvard Medical School, who was sentenced to eight years in prison after he pleaded guilty to stealing and selling human remains on the black market.

A Massachusetts court has granted preliminary approval to the settlement. The final approval is expected in December this year.

The case has not only raised disturbing questions about Lodge's actions, but also about how donated human remains are protected inside a reputed medical institution.

Deeper Glimpse Into The Case

Lodge worked at Harvard Medical School's morgue and had access to bodies donated to the school under their Anatomical Gift Program.

Federal prosecutors said that between 2018 and March 2020, instead of disposing remains according to the agreement, Lodge removed "heads, brains, skin and bones", and other body parts from donated cadavers after they had been used for teaching and research.

He allegedly transported the remains from the Harvard morgue in Boston to his home in New Hampshire, where he and his wife, Denise Lodge, sold them to buyers in different states. Some of the buyers subsequently resold the parts.

According to a statement from the US Attorney's Office, "At times, Cedric Lodge allowed [others] to enter the morgue at Harvard Medical School and examine cadavers to choose what to purchase."

Also read: Organ Donation: The Gift Of Life

When Did The Scandal Become Public?

The scandal came to light in 2023, when Lodge and several others were charged in the trafficking scheme. Lodge sentenced to eight years in federal prison in December 2025, while his wife, Denise Lodge, received a sentence of one year and one day for her involvement.

Other people who purchased remains from Lodge have also pleaded guilty and been sentenced. Katrina Maclean from Massachusetts, and Joshua Taylor from Pennsylvania, allegedly purchased body parts from Lodge.

According to the charging statement, in October 2020, Ms Maclean purchased dissected faces for $600 that she intended to have tanned into leather.

Ms Maclean owns a store called Kat's Creepy Creations. The business's social media page showed she specialised in up-cycling dolls into blood-soaked, horror novelties.

It is not confirmed if the cadaver parts were used in her products. The indictment alleges she stored and sold human remains at the store.

Mr Taylor allegedly bought several stolen body parts from Ms Lodge over the course of four years, worth more than $37,000. The indictment included a particularly grim reference to a PayPal memo for a purchase of $1,000 (£790) that allegedly read, "head number 7".

United States Attorney Gerard M. Karam said, "Some crimes defy understanding." He added, "The theft and trafficking of human remains strikes at the very essence of what makes us human."

George Q. Daley, Dean of the Faculty of Medicine at Harvard University, said he was "appalled to learn that something so disturbing could happen on our campus".

He said in a statement, "We are so very sorry for the pain this news will cause for our anatomical donors' families and loved ones, and Harvard Medical School pledges to engage with them during this deeply distressing time."

He also confirmed that Cedric Lodge was terminated on May 6.

Also read: World Organ Donation Day 2026: Too Old Or Too Sick To Donate Organs? Doctors Bust Key Myths

Families Questioned Harvard's Moral Responsibility

The criminal case against Lodge is separate from the civil lawsuits against Harvard. The families who donated the remains of their loved ones argued that Harvard had a responsibility to properly safeguard those bodies. Their lawsuits accused the university and medical school of negligence and breach of their duties toward donors and their families.

The case is particularly sensitive because body donation depends heavily on trust and respect. People who donate their remains generally do so with the expectation that they will be treated respectfully and used for legitimate medical education or research.

In October 2025, Massachusetts' highest court allowed the lawsuits against Harvard to proceed after an earlier dismissal, clearing the way for the settlement.

What Does The $53 Million Settlement Include?

The financial settlement will compensate families financially involved in the lawsuits. But Harvard has also agreed to certain non-financial compensation.

The institution will hold a live webinar with affected families and publicly acknowledge that Lodge's actions were “morally reprehensible” and inconsistent with Harvard's standards for treating anatomical donors and their loved ones.

Harvard also plans to create an annual scholarship for medical students, beginning in the 2027-28 academic year, in honour of people who donated their bodies to the school's Anatomical Gift Program.

Harvard Medical School Dean George Daley and Dean for Medical Education Bernard Chang said the settlement would allow the university and families to avoid prolonged litigation, while acknowledging the devastating impact of the scandal.

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