Stomach cancer (credit: canva)
Stomach cancer is a type of cancer that develops in the lining of the stomach. Also, known as Gastric cancer, it affects the elderly more than the adult. According to the American Cancer Society, about 6 of every 10 people diagnosed with stomach cancer each year are 65 or older. Also, the lifetime risk of developing stomach cancer is higher in men (about 1 in 101) than in women (about 1 in 155).
A health expert, speaking to a leading media house, emphasized five common symptoms of stomach cancer that should not be ignored:
1. Unexplained weight loss: Losing weight without trying or experiencing an unexplained drop in appetite, which may signal cancer progression.
2. Pain in the upper part of the abdomen: Persistent or occasional pain in the stomach area, often after eating, can become more severe as the condition progresses.
3. Frequent vomiting after meals: Nausea, sometimes accompanied by vomiting, may occur especially after meals and is linked to cancer blocking or irritating the stomach.
4. Vomiting blood, which may appear coffee-colored: This can indicate bleeding in the stomach, often caused by ulcers or tumors, and requires immediate medical attention.
5. Black, tarry stools: This occurs when blood from the stomach is digested and passed through the intestines, signaling potential internal bleeding
There are also other concerning signs that should not be overlooked such as jaundice, unexplained weight loss, early onset of diabetes, dark stools, and loss of appetite. Health experts strongly advise seeking immediate medical attention if you notice any of these symptoms. If you or a loved one experience these signs, it's crucial to visit a physician for a thorough evaluation to rule out serious underlying health conditions.
Oncologist Dr Pankaj Kumar Pande, Director–Surgical Oncology, Max Super Specialty Hospital, Shalimar Bagh, Delhi explained that this form of cancer spreads through three main pathways: Direct spread, lymphatic spread, and bloodstream.
1. Direct Spread: In its early stages, stomach cancer can invade nearby tissues and grow into the deeper layers of the stomach or spread to surrounding organs such as the oesophagus, liver, pancreas, or intestines.
2. Lymphatic Spread: Cancer cells can travel through the lymphatic system. The most common areas affected are the regional lymph nodes near the stomach, particularly those around the liver and diaphragm.
3. Bloodstream: "Cancer cells can enter the bloodstream and travel to distant parts of the body," which is a common route for stomach cancer to metastasize to distant organs.
He further explained that cancerous cells spread from the original tumour to other parts of the body through a process called Metastasis. The most common sites for the spread are the liver, lymph nodes, peritoneum, lungs, bones, and ovaries.
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The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has introduced new measures to improve how the risks of suicidal thoughts and behaviors and persistent sexual dysfunction are communicated to people taking antidepressants.
Following a review involving patients and their families, the MHRA will introduce a boxed warning in patient information leaflets (PILs), a patient safety card, and an additional safety leaflet. The term “post-SSRI sexual dysfunction” (PSSD) will also be added to the leaflets for certain antidepressants.
“Patients need clear and accessible information about the benefits and risks of medicines so they can make informed decisions,” Dr. Alison Cave, MHRA chief safety officer, said.
She said the changes would support informed discussions among patients, caregivers, and healthcare professionals. Dr. Cave added that antidepressants can effectively treat depression when used appropriately and under clinical supervision. Patients should not stop taking these medicines without first consulting their healthcare professional.
Also read: GLP-1 Drugs May Offer Mental Health Benefits, Reduce Schizophrenia Relapses: Lancet Study
Patient information leaflets will feature a boxed warning directing readers to information about suicidal thoughts and behaviors, making the guidance easier to find.
A patient safety card is expected to accompany medicine packaging, reinforcing key safety messages and explaining when and how to seek support.
For certain antidepressants, updated leaflets will include information on PSSD, highlighting the possibility that sexual dysfunction may persist after treatment ends.
The MHRA is also developing an additional safety leaflet with the wider healthcare system. Expected in 2027, it will explain the benefits and risks of antidepressant treatment to support informed decisions. It will be given to patients at their first appointment discussing antidepressants and to those already receiving treatment.
The MHRA has received four prevention of future deaths reports since 2020 concerning antidepressant prescribing and safety information. One followed the 2024 death by suicide of Thomas Kingston, husband of Lady Gabriella Kingston, at age 45.
An inquest heard that Kingston had been prescribed sertraline and later switched to citalopram after reporting that his medication was not helping. Both are selective serotonin reuptake inhibitors (SSRIs). He had also received the sleeping tablet zopiclone for sleep difficulties and had stopped taking his medication before his death.
Gloucestershire senior coroner Katy Skerrett questioned whether patients were adequately informed about the suicide risks associated with SSRIs. Kingston’s parents called for clearer communication of potential side effects to patients and their families.
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The MHRA advises healthcare professionals to:
Patients experiencing new or worsening suicidal thoughts should seek urgent medical attention, particularly when starting treatment or changing their dose. In the UK, they can contact NHS 111, their local mental health crisis team, Samaritans on 116 123, or the SHOUT text service at 85258.
Anyone concerned about sexual dysfunction during or after antidepressant treatment should contact their healthcare professional.
The MHRA said these are not new risks associated with the medicines. Patients should read the information supplied with their medication and consult their healthcare professional before stopping treatment.
Credit: AI Image
Lead poisoning is a widespread but preventable health threat that contributes to more than 3.5 million deaths globally each year and puts hundreds of millions of children at risk, the World Health Organization (WHO) said.
Marking International Lead Poisoning Prevention Week 2026, WHO urged countries to accelerate prevention efforts amid growing global momentum to tackle lead exposure.
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Children are particularly vulnerable to lead because their developing brains and nervous systems are highly susceptible to its toxic effects. Even low levels of exposure can cause irreversible harm, affecting learning, behavior and development.
“Lead poisoning should not be stealing children's potential in 2026,” said Bruce Gordon, Director a.i. of WHO’s Department of Environment, Climate Change, One Health and Migration.
“We know where many exposures come from and we know how to prevent them. Countries now need to move upstream, removing lead from products and environments before it reaches a child's bloodstream. WHO is working with governments and partners to help turn that evidence into action,” Gordon added.
There is no known safe level of lead exposure, WHO warned. Exposure can occur through paint, cookware, cosmetics, spices, informal recycling and industrial contamination, among other sources.
Lead affects multiple organs and can contribute to cardiovascular and kidney disease in adults. In children, exposure can cause lasting damage to brain function and development. Its effects may go undetected until significant harm has occurred.
Lead is distributed to the brain, liver, kidney and bones. It is stored in the teeth and bones, where it can accumulate over time. Human exposure is assessed through the measurement of lead in blood.
Fewer than half of countries had confirmed legally binding controls on lead paint, according to WHO's latest published global assessment.
This year's International Lead Poisoning Prevention Week theme, “From Detection to Prevention,” highlights the need for stronger policies, better enforcement of safety standards and greater public awareness to eliminate lead hazards at their source.
WHO Member States have recognized lead exposure as a pressing public health concern and mandated the development of a Global Action Plan on Lead Mitigation, which will be presented to the World Health Assembly in 2027.
The WHO will also launch the PREVENT Technical Package on Lead Poisoning Prevention in 2027. It will provide practical guidance to help countries identify major exposure sources, prioritize interventions, strengthen regulations and track progress.
Last year, WHO joined partners in the Lead Poisoning Prevention Initiative to strengthen laboratory capacity for blood lead testing, supporting the monitoring and early detection of exposure.
The initiative will provide technical support and build laboratory capacity in Brazil, five states in India, Nepal and six sub-Saharan African countries: Ethiopia, Ghana, Malawi, Rwanda, South Africa and the United Republic of Tanzania.
Preventing lead exposure can also reduce health care costs, improve educational outcomes and support healthier, more productive societies.
The WHO urged countries to move beyond detecting lead exposure and adopt comprehensive prevention strategies such as:
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Scottish swimmer Archie Goodburn has welcomed the UK government’s plans to review progress in brain cancer research after years of campaigning for better treatment and greater investment in research.
Goodburn, 25, revealed in 2024 that he had been diagnosed with three inoperable brain tumors. In August, he broke down during an interview on BBC Breakfast as he spoke about the challenges faced by patients with brain cancer and their families.
He appealed to the government to invest more in research, urging it to “give us a chance to fight for our lives.” His plea led to a meeting with Prime Minister Andy Burnham.
The government has now announced a new national brain cancer clinical lead and a review of progress in brain cancer research, with the aim of helping patients access treatments sooner, the BBC reported.
Goodburn thanked the prime minister, saying all three of his requests had been “promised to some extent,” although the details still needed to be worked out.
Burnham described Goodburn as an “inspiration to us all” and said he was “delighted” to welcome him to Downing Street.
“He has spoken passionately about the need for change on brain cancer, and he's right: progress hasn't been good enough, here or anywhere else. Families facing this disease can't afford to wait,” Burnham said.
According to the BBC, the review will be led by Professor Anthony Chalmers, chair of clinical oncology at the University of Glasgow. It will assess progress in brain cancer research since 2018 and identify “what is still holding progress back.”
The review will be followed by a national cancer plan aimed at getting new treatments “out of the lab and to patients faster,” Downing Street said.
The prime minister has also asked the Medicines and Healthcare products Regulatory Agency (MHRA) to complete its review of regulations for medicines used to treat rare conditions sooner.
Goodburn has urged the regulator to finish the review within two years rather than three, bringing forward potential changes that could help patients access new treatments sooner.
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Scottish First Minister John Swinney, who also recently met Goodburn, highlighted the Scottish government's commitment to supporting more clinical trials.
“We are proud to support national leadership for brain cancer through the Scottish Adult Neuro-Oncology Network,” Swinney said.
The network brings together clinicians, patients and voluntary sector representatives to improve care for people with brain cancer across Scotland.
“We will give careful consideration to any further role which Scotland could play to give people living with brain cancer a faster route from research to treatment,” he added.
READ: Survival In Aggressive Brain Tumors Improves By Up To 50% in India, Say Doctors
The Edinburgh-born swimmer sought medical tests after experiencing numbness and seizures while training for the 2024 Olympic trials. He was diagnosed with three large oligodendrogliomas, a rare type of tumor that can affect the brain and spinal cord.
He underwent chemotherapy and radiotherapy, but surgery to remove the tumors was not possible.
Despite his diagnosis, Goodburn competed at the 2026 Commonwealth Games in Glasgow, reaching the final of the 50-meter breaststroke but narrowly missing out on a medal.
Charity Brain Tumour Research has described brain tumors as the cancer most likely to kill people under 40 in the UK.
“One of my dreams is that we see a future where brain cancer isn't the biggest killer of patients under 40,” Goodburn said during the Commonwealth Games.
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