Stomach cancer (credit: canva)
Stomach cancer is a type of cancer that develops in the lining of the stomach. Also, known as Gastric cancer, it affects the elderly more than the adult. According to the American Cancer Society, about 6 of every 10 people diagnosed with stomach cancer each year are 65 or older. Also, the lifetime risk of developing stomach cancer is higher in men (about 1 in 101) than in women (about 1 in 155).
A health expert, speaking to a leading media house, emphasized five common symptoms of stomach cancer that should not be ignored:
1. Unexplained weight loss: Losing weight without trying or experiencing an unexplained drop in appetite, which may signal cancer progression.
2. Pain in the upper part of the abdomen: Persistent or occasional pain in the stomach area, often after eating, can become more severe as the condition progresses.
3. Frequent vomiting after meals: Nausea, sometimes accompanied by vomiting, may occur especially after meals and is linked to cancer blocking or irritating the stomach.
4. Vomiting blood, which may appear coffee-colored: This can indicate bleeding in the stomach, often caused by ulcers or tumors, and requires immediate medical attention.
5. Black, tarry stools: This occurs when blood from the stomach is digested and passed through the intestines, signaling potential internal bleeding
There are also other concerning signs that should not be overlooked such as jaundice, unexplained weight loss, early onset of diabetes, dark stools, and loss of appetite. Health experts strongly advise seeking immediate medical attention if you notice any of these symptoms. If you or a loved one experience these signs, it's crucial to visit a physician for a thorough evaluation to rule out serious underlying health conditions.
Oncologist Dr Pankaj Kumar Pande, Director–Surgical Oncology, Max Super Specialty Hospital, Shalimar Bagh, Delhi explained that this form of cancer spreads through three main pathways: Direct spread, lymphatic spread, and bloodstream.
1. Direct Spread: In its early stages, stomach cancer can invade nearby tissues and grow into the deeper layers of the stomach or spread to surrounding organs such as the oesophagus, liver, pancreas, or intestines.
2. Lymphatic Spread: Cancer cells can travel through the lymphatic system. The most common areas affected are the regional lymph nodes near the stomach, particularly those around the liver and diaphragm.
3. Bloodstream: "Cancer cells can enter the bloodstream and travel to distant parts of the body," which is a common route for stomach cancer to metastasize to distant organs.
He further explained that cancerous cells spread from the original tumour to other parts of the body through a process called Metastasis. The most common sites for the spread are the liver, lymph nodes, peritoneum, lungs, bones, and ovaries.
Credit: AI
Your eyes may explain a lot about how your brain handles attention. A new Indian study suggests that tiny fluctuations in the pupils may provide a physiological clue to attention related differences in children with ADHD.
Researchers from the Indraprastha Institute of Information Technology Delhi analysed eye-tracking data from 50 children aged 10 to 12, including 28 children with combined-type ADHD and 22 without a neurodevelopmental diagnosis. These findings were published in Scientific Reports.
Instead of just looking at the size of the pupils, researchers examined how pupil responses shifted from one trial to another while children performed a working-memory task.
During the experiment, children watched dots appear on a grid and had to remember their positions while ignoring distractions. An eye tracker recorded their pupil diameter 1,000 times per second.
After accounting for age, IQ and memory-task difficulty, the researchers estimated that unmedicated children with ADHD had about 23% greater trial-to-trial variability in their pupil responses than children in the control group.
Among the unmedicated children with ADHD, greater pupil variability was also associated with poorer accuracy on the task.
The pattern was, however, more complicated. Within individual trials, pupil variability was actually lower in the ADHD group. This suggests that different measures of pupil dynamics may capture different aspects of attention and brain activity.
Also read: Increased Screen Timings Have Lead to ADHD: Key Symptoms
The researchers also looked at 17 children with ADHD who completed the task both after taking their usual methylphenidate medication and after stopping it for 24 hours.
When the children were taking medication, their pupils showed a stronger response during the task and less variation between trials. Their overall pupil-response pattern also became more similar to that of the control group. But the researchers caution against interpreting this as proof that medication normalising attention span.
Methylphenidate can itself influence physiological systems that affect pupil size, meaning the study could not completely separate the drug's direct effects on the pupils from changes related to attention.
Also read: Using AI Apps To Manage ADHD? How They Can Help And Why Experts Urge Caution
There is no single biological test for ADHD currently. Diagnosis involves clinical assessment, developmental history and behavioural symptoms across different settings and circumstances.
The study itself has several limitations. For instance, it was based on a small sample, used existing eye-tracking data and involved a controlled laboratory task rather than everyday environments like classrooms.
Although the statistical model found greater trial-to-trial pupil variability, the direct participant-level difference between the ADHD and control groups did not remain statistically significant after correction for multiple comparisons.
The researchers therefore describe pupil dynamics as a useful source of additional physiological information, rather than a diagnostic test.
First author Saumya Yadav said, "It is still too early to consider pupil measurements as a clinical diagnostic tool.”
Larger studies will need to determine whether these pupil patterns can reliably distinguish ADHD from other conditions and whether they remain consistent outside laboratory settings.
Credit: AI
A recent AI analysis of more than 400,000 Reddit posts about popular GLP-1 drugs like Ozempic, Wegovy, Mounjaro and Zepbound revealed several side effects that researchers may not have fully recorded in clinical trials.
The study, published in Nature Health, analysed 410,198 Reddit posts from May 2019 through June 2025. Researchers identified 67,008 people who self-reported using semaglutide or tirzepatide, with 43.5% reporting at least one side effect.
The findings do not prove that the drugs caused the symptoms. Instead, they did identify patterns in patients' own accounts that may need further investigation.
As expected, the analysis found gastrointestinal symptoms in majority. Among GLP-1 users who reported side effects, the most common were:
Researchers also found abdominal pain, reduced appetite, acid reflux, bloating, headache and dizziness among commonly reported symptoms.
But two groups of symptoms stood out as they may be less represented in existing clinical-trial data and drug information. They are reproductive symptoms and complaints associated with temperature.
Nearly 4% of people who reported side effects described reproductive symptoms, including irregular menstrual cycles, bleeding between periods and heavy bleeding.
GLP-1 drug users also described chills, feeling unusually cold, hot flashes and fever-like sensations.
Also read: GLP-1 Drugs Mounjaro, Zepbound Show Promise For 1 Billion With Sleep Apnea
The study was based on self-reported social-media posts, so researchers cannot establish whether semaglutide or tirzepatide directly caused menstrual changes, chills or hot flashes.
Other factors may also influence these symptoms. People taking GLP-1 drugs may experience substantial weight loss, changes in food intake, metabolic changes or other health changes that could effect these symptoms.
The researchers therefore describe these findings as safety signals, rather than confirmed adverse effects.
Clinical trials help in determining whether a medication is effective. They also help in identifying its potential side-effects. But once millions of people begin using a drug, patients may describe symptoms in everyday settings that were uncommon or not specifically investigated during trials.
Reddit provides researchers with a huge data collection of real-world experiences. AI can quickly scan hundreds of thousands of posts for recurring symptom patterns that would be extremely difficult to identify manually.
However, Reddit users are not representative of all people taking GLP-1 drugs. The researchers noted that the population studied was younger, more likely to be male and disproportionately based in the US.
The study does not provide evidence that people should stop Ozempic, Mounjaro or other GLP-1 medications. Instead, it shows how AI-assisted analysis of patient experiences could help in addition to traditional drug-safety trials and monitoring.
Common symptoms of GLP-1 medications remain nausea, vomiting, diarrhoea and constipation as they are backed by extensive research and clinical trials.
The newly highlighted symptoms, particularly menstrual and temperature-related changes, need clinical research to determine whether they are genuinely caused by the drugs.
Credit: AI
Globally renowned beauty and haircare brand L’Oréal is in the midst of a new legal battle in the US over allegations that it did not warn consumers possible potential cancer risks linked with its chemical hair-relaxer products.
Arizona Attorney General Kris Mayes filed a consumer fraud lawsuit against L’Oréal USA, its parent company and SoftSheen, accusing the companies of selling chemical hair relaxers without disclosing alleged links to ovarian and uterine cancers. Arizona is the first US state to bring such a lawsuit against L’Oréal over the products.
The lawsuit alleges that the products were primarily marketed to African American women and, in some cases, children.
The state is seeking damages and penalties, including warnings if the brand wants to keep selling the products.
Chemical hair relaxers are highly alkaline products designed to permanently straighten textured hair. They work by breaking and reforming the disulfide bonds in keratin, which gives hair its natural shape.
According to the Arizona lawsuit, some chemical relaxer products contain substances including phthalates, parabens, and other chemicals classified as probable carcinogens.
The complaint states that repeated use can increase exposure as these products are applied directly onto the scalp.
However, the presence of a potentially hazardous chemical does not establish that using a particular product will cause cancer. Cancer risk depends on factors including the substance, dose, duration, and route of exposure.
Also read: Prostate Cancer: What's Fact, What's Fiction
The legal action follows years of scientific research that examined links between chemical hair relaxers and cancers related to hormones.
A 2022 study from the US National Institutes of Health found that women who reported frequent use of chemical hair-straightening products had more than twice the risk of developing uterine cancer compared with women who did not use them frequently.
The researchers, however, found an association, not proof that hair relaxers directly caused these cancers.
Other research has also investigated possible links with ovarian and breast cancers, adding to concerns about repeated exposure to chemicals may cause serious health conditions.
Also read: Beyond Vaccines And Nutrition: Why Childhood Cancer Needs A Wider Conversation
According to Reuters, L’Oréal has rejected the allegations. A spokesperson for L’Oréal USA said that the company is confident in the safety of its products and considers that the claims lack legal and scientific merit.
The company said, “L’Oréal’s highest priority is the health and well-being of all our consumers. Our products are subject to a rigorous scientific evaluation of their safety by experts who also ensure that we strictly follow all regulations in every market in which we operate. We are confident in the safety of SoftSheen-Carson’s products and believe the allegations made in this lawsuit have neither legal nor scientific merit.”
L’Oréal also disputes the research underlying the litigation, saying the study cited by plaintiffs did not establish a causal connection between hair-relaxer use and the alleged health conditions and called for further research.
The Arizona lawsuit comes amid more than 12,000 similar lawsuits consolidated in a federal multidistrict litigation in Chicago involving L’Oréal, Revlon and other manufacturers. Trials in that litigation may start in 2027.
The current evidence does not mean that everyone who has used a chemical hair relaxer will develop cancer.
But repeated use is an area of ongoing scientific investigation. People who use these products can reduce unnecessary exposure by following product instructions carefully, avoiding application to irritated or damaged skin, and considering less frequent use or non-chemical alternatives.
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