Stomach cancer (credit: canva)
Stomach cancer is a type of cancer that develops in the lining of the stomach. Also, known as Gastric cancer, it affects the elderly more than the adult. According to the American Cancer Society, about 6 of every 10 people diagnosed with stomach cancer each year are 65 or older. Also, the lifetime risk of developing stomach cancer is higher in men (about 1 in 101) than in women (about 1 in 155).
A health expert, speaking to a leading media house, emphasized five common symptoms of stomach cancer that should not be ignored:
1. Unexplained weight loss: Losing weight without trying or experiencing an unexplained drop in appetite, which may signal cancer progression.
2. Pain in the upper part of the abdomen: Persistent or occasional pain in the stomach area, often after eating, can become more severe as the condition progresses.
3. Frequent vomiting after meals: Nausea, sometimes accompanied by vomiting, may occur especially after meals and is linked to cancer blocking or irritating the stomach.
4. Vomiting blood, which may appear coffee-colored: This can indicate bleeding in the stomach, often caused by ulcers or tumors, and requires immediate medical attention.
5. Black, tarry stools: This occurs when blood from the stomach is digested and passed through the intestines, signaling potential internal bleeding
There are also other concerning signs that should not be overlooked such as jaundice, unexplained weight loss, early onset of diabetes, dark stools, and loss of appetite. Health experts strongly advise seeking immediate medical attention if you notice any of these symptoms. If you or a loved one experience these signs, it's crucial to visit a physician for a thorough evaluation to rule out serious underlying health conditions.
Oncologist Dr Pankaj Kumar Pande, Director–Surgical Oncology, Max Super Specialty Hospital, Shalimar Bagh, Delhi explained that this form of cancer spreads through three main pathways: Direct spread, lymphatic spread, and bloodstream.
1. Direct Spread: In its early stages, stomach cancer can invade nearby tissues and grow into the deeper layers of the stomach or spread to surrounding organs such as the oesophagus, liver, pancreas, or intestines.
2. Lymphatic Spread: Cancer cells can travel through the lymphatic system. The most common areas affected are the regional lymph nodes near the stomach, particularly those around the liver and diaphragm.
3. Bloodstream: "Cancer cells can enter the bloodstream and travel to distant parts of the body," which is a common route for stomach cancer to metastasize to distant organs.
He further explained that cancerous cells spread from the original tumour to other parts of the body through a process called Metastasis. The most common sites for the spread are the liver, lymph nodes, peritoneum, lungs, bones, and ovaries.
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The US Food and Drug Administration (FDA) has announced to hold a public hearing on the potential therapeutic use of psychedelic drugs, as the Donald Trump administration pushes to accelerate research and development of these treatments for serious mental illnesses.
The hearing, it said, will examine their potential use in supervised and supportive settings, including patient safety, provider training, access and data collection.
In a statement, the FDA said it is collaborating with federal partners and holding “this public hearing to obtain feedback and perspectives on issues associated with the potential future therapeutic use of drug products containing a psychedelic drug substance in supervised and supportive settings”.
Also read: Ibogaine: Why Donald Trump Is Pushing US FDA To Fast-track This Psychedelic
The hearing will focus on what would be needed for the potential therapeutic use of psychedelic drugs in supervised and supportive settings.
Key areas include:
Emerging research shows psychedelics can help improve mental health, especially in conditions where traditional treatment approaches have not been useful. However, these drugs also come with several health risks that cannot be overlooked.
The hearing is part of broader US efforts to increase clinical trial participation, data sharing and real-world evidence on psychedelic drugs. The FDA hearing does not amount to approval of psychedelic treatments. Instead, it could help shape how the US approaches their potential future use in medical care.
The FDA has already taken steps to speed up the development of psychedelic treatments for mental health conditions.
In April 2026, the agency issued national priority vouchers to companies studying psilocybin for treatment-resistant depression (TRD), psilocybin for major depressive disorder (MDD), and methylone for post-traumatic stress disorder (PTSD).
The FDA has also granted Breakthrough Therapy designation to psychedelic drug programs involving MDMA for PTSD and psilocybin for TRD and MDD.
Research over the past decade has suggested that MDMA-assisted therapy may help reduce PTSD symptoms, while psilocybin-assisted therapy has shown promise for treatment-resistant depression in clinical studies.
For people who do not get lasting relief from existing treatments such as antidepressants and psychotherapy, psychedelic-assisted therapy could potentially offer another treatment option.
However, these designations and regulatory steps do not mean that these drugs have been approved as safe or effective treatments. Neither a national priority voucher nor Breakthrough Therapy designation is a substitute for FDA marketing approval.
The push has expanded beyond the FDA. In 2026, the White House, Congress and the Department of Veterans Affairs (VA) have also become involved in efforts to accelerate research into psychedelic treatments, including psilocybin, MDMA and ibogaine.
The US Department of Health and Human Services (HHS) has partnered with the VA to accelerate the development of psychedelic-assisted therapies for veterans with conditions including PTSD, depression and traumatic brain injury.
Separately, a bipartisan group of lawmakers introduced a bill that would require the US Department of Defense to evaluate whether ongoing psychedelic research, particularly involving psilocybin, could benefit active-duty service members and veterans transitioning to civilian life.
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A total of 1,370 mpox cases and seven deaths were reported globally in July, according to the World Health Organization (WHO), which continues to assess the global public health risk from the multi-country outbreak as moderate.
The WHO external situation report, published today, is based on data from 32 countries across four WHO regions. The case fatality ratio (CFR) was 0.5%.
About three-quarters of the cases were reported in the WHO African Region.
Madagascar reported the highest number of cases, with 703 cases and seven deaths, followed by Angola (138), China (88), the Democratic Republic of the Congo (85) and Kenya (55).
Between July 6 and August 16, Madagascar reported 785 cases, while deaths remained at seven. Angola reported 184 cases, Kenya 94, the Democratic Republic of the Congo 41 and Cameroon 28.
The WHO noted that Congo's figures may be affected by delays in mpox reporting as the country focuses on its response to the Bundibugyo virus disease outbreak.
From January 1, 2025, to July 31, 2026, a total of 65,784 mpox cases and 264 deaths were reported across 105 countries.
“WHO conducted a global mpox rapid risk assessment in August 2026; the overall global public health risk associated with the mpox multi-country outbreak was again assessed as moderate,” the WHO said.
“WHO continues to consider the ongoing multi-country mpox outbreak a graded emergency, with new outbreaks reported in multiple countries and over a thousand confirmed cases reported every month,” it added.
The WHO urged countries and partners to maintain mpox surveillance, notification and coordinated preparedness and response activities.
The WHO Director-General's standing recommendations on mpox have been extended until August 2027.
Mpox transmission continues to affect key populations, largely through sexual transmission, followed by household spread and community outbreaks. All clades of monkeypox virus (MPXV) continue to circulate.
In July, the African Region reported more confirmed cases than in June, while the Americas, Western Pacific, European and South-East Asia regions reported fewer cases. The Eastern Mediterranean Region reported no confirmed cases.
Eleven African countries reported active transmission between July 6 and August 16, with 1,153 confirmed cases and seven deaths.
Chile and Hungary reported clade Ib MPXV for the first time. Several European countries, including the UK, have reported community transmission of clade Ib.
The first human trial of BNT166a, an mRNA-based mpox vaccine developed by BioNTech, showed encouraging early results.
The vaccine was generally safe and well tolerated and triggered strong antibody responses across all dose levels, including in people who had and had not previously received vaccination against related viruses.
The trial involved 64 adults and was primarily designed to assess safety and immune responses, rather than whether the vaccine prevents infection.
“These findings are an important step forward in the development of a new generation of vaccines against mpox. We’ve shown that this mRNA vaccine approach can safely generate strong immune responses in people, which is very encouraging," said Professor Saul Faust, UK Chief Investigator for the trial.
The vaccine is now progressing to a larger trial to assess its effectiveness in real-world settings.
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Lung cancer is the leading cause of cancer cases and deaths worldwide, with an estimated 2.5 million new cases and 1.8 million deaths in 2022.
Lung cancer is often diagnosed at later stages, when five-year survival rates are lowest. Now, two drugs developed by pharma giants GSK and BioNTech have shown promising results in major clinical trials.
Data presented at the ongoing International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC) in Seoul, South Korea, showed that the drugs could improve survival and produce high tumour response rates in patients with certain types of non-small cell lung cancer (NSCLC).
GSK's Jideytro Shows 94% Response Rate
GSK announced positive results from the ARROS-1 trial evaluating Jideytro (zidesamtinib) in patients with ROS1-positive NSCLC who had not previously received treatment with a tyrosine kinase inhibitor.
Among patients who had not previously received a tyrosine kinase inhibitor (TKI), an oral targeted therapy, Jideytro triggered an objective response in 88 patients, giving an objective response rate of 94%.
These patients were allowed to have received up to one prior line of chemotherapy, with or without immunotherapy, before entering the study.
GSK reported that 90% of patients remained progression-free at 12 months. Notably, 70% of patients with brain metastases saw complete clearance of detectable tumors.
With the promising results, the company said it will apply for a supplemental New Drug Application to the US Food and Drug Administration later this year to expand Jideytro's approval into first-line use.
Jideytro was already approved in July 2026 for previously treated patients with advanced ROS1-positive NSCLC.
German biopharmaceutical company BioNTech said its experimental immunotherapy gotistobart (BNT316/ONC-392) produced a significant overall-survival benefit in the Phase 3 PRESERVE-003 trial in previously treated metastatic squamous NSCLC.
Gotistobart is an investigational immunomodulator that targets CTLA-4 and is designed to selectively enhance regulatory T-cell depletion in the tumor microenvironment.
According to the company, median overall survival was 18.5 months with gotistobart, compared with 10.0 months with standard-of-care docetaxel chemotherapy, nearly doubling median survival in this patient population.
The findings suggest potential for gotistobart as a chemotherapy-free treatment approach in previously treated patients with squamous NSCLC.
“The magnitude of the survival benefit observed with gotistobart as a chemotherapy-free treatment approach in the PRESERVE-003 clinical trial is highly encouraging. If confirmed in the pivotal portion of the Phase 3 trial, these findings could transform the standard of care in a setting where new therapies are urgently needed,” said Rama Balaraman, Principal Investigator and medical oncologist at Ocala Oncology Center, Florida, US.
Lung cancer is a serious disease and remains a major public health challenge worldwide due to its high incidence and mortality.
Lung cancer occurs when abnormal cells grow uncontrollably in the lungs. Treatment depends on a person's medical history and the stage of the disease.
The two main types of lung cancer are non-small cell lung cancer (NSCLC), which accounts for around 85% of cases, and small cell lung cancer (SCLC), which is less common but typically more aggressive.
With a five-year relative survival rate of 15% and a median overall survival of 11 months in the United States between 2000 and 2017, squamous NSCLC is a devastating disease with limited treatment options.
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