FDA Has Approved A New Medication Treatment For Migraines In Adults

Updated Feb 6, 2025 | 05:09 PM IST

SummaryMany people use the terms ‘migraine’ and ‘headache’ interchangeably. This leads many people to believe that migraines are not as serious as people make them out to be, and that cannot be more wrong, migraines have a major effect on a person’s lifestyle and the new approved medication may prove to be a great relief!
(Credit-Canva)

(Credit-Canva)

Headaches are a common symptom of a stressful lifestyle, your body not feeling well and other issues. While headaches can be dealt with easily, migraines are not so easy to handle. Migraines are a type of headache that feels like severe throbbing and pulsing sensation, almost like you are hearing your own heartbeat in your brain, usually on one side of the brain. Many people believe that migraines are not that big of a deal because you just have to deal with the pain, but that is not all migraine is, some people find it very difficult to do their daily tasks as they experience dizzying spells, nausea and extreme sensitivity to light and sound! These attacks can last hours and make it difficult for people to go about their daily lives as well. While there are medications available for migraine patients, these medications need time to take effect, so you may be in a lot of pain, but there are not many quick reliefs you can have in place other than learning the symptoms of a migraine attack and taking medication before it happens. But a new approval by the FDA may change this!

The U.S. Food and Drug Administration (FDA) has approved Symbravo, a new medicine to treat acute migraine attacks in adults. This means adults can now use Symbravo to get relief from their migraine symptoms. The FDA's decision was based on the results of three big studies, called Phase 3 trials. These trials involved over 21,000 migraine attacks, so the FDA has a lot of information about how well Symbravo works and how safe it is. The FDA only approves medicines that have been shown to be both safe and effective through a thorough testing process.

Importance of New Treatment Option

"Migraine attacks can happen suddenly and really mess up people's lives. It's estimated that over 39 million people in the U.S. alone get migraines," said Herriot Tabuteau, M.D., CEO of Axsome Therapeutics told US News. This shows how common migraines are and how important it is to have good treatments. "Symbravo gives patients and doctors a new option that can quickly stop a migraine attack, keep it away, and let people get back to their normal activities, all with just one dose." Having a medicine that can give fast and long-lasting relief from migraine pain is a big deal for millions of people. This new treatment is a real step forward in how we treat migraines.

Symbravo Trial Results, How Was It Approved

The trials took place in 3 steps, the Momentum trial study focused on people whose migraines had moderate to severe pain. The results showed that a lot more people taking Symbravo felt pain-free two hours after taking the medicine compared to those who took a placebo which is a dummy pill. Even better, many people felt relief for up to 24 and even 48 hours after just one dose. This long-lasting relief is really important for people with migraines because it means they can get back to their normal lives without worrying about the pain coming back. The study also looked at how many people were free from their worst symptom, like sensitivity to light or sound, or nausea. Symbravo worked better than the placebo in this area too.

While the intercept trial looked at people who took Symbravo when their migraine pain was still mild. Even when the pain was just starting, Symbravo was effective. The results were similar to the MOMENTUM trial, with many people getting pain relief and relief from their worst symptoms. Treating migraines early is often better because it can stop the pain from getting really bad.

And lastly the Movement trial which was to see how safe the medication is when people take it regularly. This study followed 706 people who had at least two migraines a month. The most common side effects people experienced were sleepiness and dizziness. While these side effects are important to know about, the study showed that Symbravo is generally safe for people to use on a regular basis.

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Nearly 8 In 10 US Young Adults Show Signs Of Heart, Kidney Risk: Why Early Checks Matter

Updated Sep 2, 2026 | 06:00 PM IST

SummaryYoung adults do not necessarily need extensive cardiac investigations simply because of their age. However, those who are overweight, have high blood pressure, abnormal cholesterol, diabetes or a family history of premature heart disease should consider regular health checks.
Nearly 8 In 10 US Young Adults Show Signs Of Heart, Kidney Risk: Why Early Checks Matter

Credit: American College of Cardiology Foundation and the American Heart Association

A new study found that nearly 8 out of 10, or 80%, of young adults in the US, with an average age of 23, had cardiovascular-kidney-metabolic (CKM) syndrome.

Published in Circulation: Population Health and Outcomes, the study found that these young adults had CKM syndrome at Stage 1, 2 or 3, meaning they had excess adiposity, metabolic risk factors and/or evidence of subclinical cardiovascular disease.

Young Adults Already Showing CKM Risk

The study included 1,283 young adults from large US cities. About 21% had no identifiable CKM risk factors (Stage 0), while none were in Stage 4.

More advanced CKM stages were associated with early arterial injury, including thicker carotid artery walls, an early marker of atherosclerosis, even among people in their early 20s.

Researchers said the findings highlight the need to begin prevention earlier in life. They also suggested promoting the American Heart Association’s Life’s Essential 8 early in life to improve cardiovascular health.

Life’s Essential 8 focuses on

  • healthy eating,
  • physical activity,
  • avoiding tobacco,
  • healthy sleep,
  • healthy weight,
  • healthy cholesterol,
  • healthy blood sugar,
  • healthy blood pressure.
Also read: Obesity-Driven CKM Syndrome A Growing Public Health Threat, Warns American Heart Association

What The Findings Mean For Young Adults

“The findings are important because they show that cardiovascular risk can begin building much earlier than we traditionally expect. We often associate heart disease with middle age or older adults, but risk factors such as excess weight, high blood pressure, abnormal cholesterol and elevated blood sugar can develop silently in young adults,” Dr. Gobu P, Senior Consultant Cardiology, Gleneagles Chennai, told HealthandMe.

Dr. Chetan Kumar H. B, Senior Consultant, Cardiology, Fortis Hospital, Bannerghatta Road, Bengaluru, added that heart, kidney and metabolic health issues can start much earlier than traditionally thought. While heart disease becomes more common with age, the risk factors that lead to it can begin developing in early adulthood.

The findings do not mean that these young adults already have heart disease. Rather, the association between advanced CKM risk and early arterial changes highlights the importance of identifying and addressing risk factors early.

Why Early Checks Matter

Read More: Fifth Universal Definition of Myocardial Infarction: What the 3 New Heart Attack Categories Mean

Young adults do not necessarily need extensive cardiac investigations simply because of their age. However, those who are overweight, have high blood pressure, abnormal cholesterol, diabetes or a family history of premature heart disease should consider regular health checks.

“Monitoring blood pressure, blood sugar, cholesterol and maintaining a healthy weight can help identify risks early. Early intervention through lifestyle changes, and medication when required, can significantly reduce the chances of cardiovascular disease later in life,” Dr. Gobu said.

Dr. Chetan noted that unhealthy eating habits, lack of physical activity, obesity, high blood pressure, abnormal cholesterol and rising blood sugar levels are increasingly seen at younger ages. These problems can develop silently and gradually affect the heart, kidneys and blood vessels.

“Young adults should not wait until they are symptomatic to start paying attention to their health. Simple tests like blood pressure, blood sugar, cholesterol and weight can go a long way in identifying risks early, especially in those with a family history of diabetes, hypertension, kidney or heart disease," he told HealthandMe.

The experts stressed that the findings should be viewed as a call for prevention rather than alarm. Identifying and addressing risk factors early could help protect long-term heart, kidney and metabolic health.

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New AI Toothbrush Films Inside Your Mouth, Spots Missed Areas & Targets Them: How Could It Improve Oral Health?

Updated Sep 2, 2026 | 04:14 PM IST

SummaryA newly-developed AI toothbrush lets you see your teeth while you brush and helps you cover spots you are most likely to miss.
New AI Toothbrush Films Inside Your Mouth, Spots Missed Areas & Targets Them: How Could It Improve Oral Health?

Credit: X

Gone are the days when teeth brushing involved just a toothbrush and toothpaste. It seems that the future of ultimate oral health is here as a newly developed AI toothbrush lets you see parts of your mouth to see parts that you may miss.

The electric toothbrush with a built-in camera and machine-learning technology that watches the mouth while you brush. The device is designed to identify gaps between teeth in real time and direct a targeted stream of mouth rinse into those areas.

The technology is aimed at the spaces between teeth, one of the most easily missed parts of daily oral hygiene.

How Does The Camera Toothbrush Work?

The toothbrush has a 100,000-pixel macro-lens camera built into the brush head. Its Gap Optical Targeting system analyses 28 images every second, using machine learning to detect, track and predict the position of gaps between teeth.

When it identifies a gap, the toothbrush can automatically trigger a precision conical jet of mouth rinse, directing up to 0.15ml of liquid between the teeth.

In other words, instead of simply brushing over the surfaces of the teeth, the device attempts to identify where cleaning is being missed and target those areas while you continue brushing.

The camera also streams live footage to a specifically designed app, allowing users to see their brushing technique and coverage.

Also read: Vitamin D3 Outperforms D2 In Maintaining Muscle, Heart Function, Shows ICMR Study

The Gaps Between Teeth Are Important

Brushing alone cannot adequately reach every tight space between teeth. Food particles and plaque can become trapped there, allowing bacteria to accumulate.

If plaque remains undisturbed, it can harden into tartar and contribute to gum irritation, bleeding gums, bad breath, and gum disease. Interdental cleaning, therefore, is an important part of oral hygiene alongside brushing. Rather than relying on people remembering to floss separately, the device combines brushing and targeted cleaning with a jet.

Also read: Scientists Warn Common Diabetes Drug Taken By Millions Could Cause Life-Threatening 'Diabetic Attack'

Could It Actually Improve Oral Health?

Dyson says its toothbrush, named Camerajet, has been clinically shown to improve gum health in two weeks when used with its low-foaming mouth rinse compared with a manual toothbrush.

It says its brushing system can remove up to 69% more plaque than leading electric toothbrushes. However, evidence is limited, so they should not be interpreted as proof that the device is superior to every existing electric toothbrush or professional dental care.

According to the The Guardian, the British Dental Association cautioned that expensive technology is not a replacement for maintaining consistent oral hygiene.

The Future Of Brushing?

The more interesting feature of the toothbrush is that it can respond to what it sees. Most toothbrushes provide instructions about where and how long to brush.

The AI brush attempts to take that a step further by detecting areas that need attention and directing cleaning there in real time.

Additionally, unlike traditional water flossers that typically use a needle-shaped stream, this brush uses a broader, cone-shaped jet that sprays mouth rinse across a wider area between the teeth.

But even the smartest toothbrush cannot replace regular dental check-ups, professional cleaning when needed, or a consistent oral-care routine.

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Scientists Warn Common Diabetes Drug Taken By Millions Could Cause Life-Threatening 'Diabetic Attack'

Updated Sep 2, 2026 | 01:00 PM IST

SummaryA team of Swedish researchers found that a class of common diabetes drugs increased the risk of diabetic ketoacidosis in underweight patients.
Scientists Warn Common Diabetes Drug Taken By Millions Could Cause Life-Threatening 'Diabetic Attack'

Credit: iStock

A type of common diabetes drugs prescribed to millions of diabetics has hidden, life-threatening complications, especially among those with certain risk factors.

The findings are based on a new study published in The Lancet Diabetes & Endocrinology. It studied nearly 280,000 people with type 2 diabetes treated with SGLT2 inhibitors, a class of drugs that includes dapagliflozin, empagliflozin, canagliflozin and ertugliflozin.

A research team from Karolinska Institute found that some patients were more likely to develop diabetic ketoacidosis (DKA) while taking these drugs.

The research comes after a study showed deaths from ketoacidosis are on the rise in the UK. Last year researchers from Imperial College London found ketoacidosis cases increased by a massive percentage of 81 per cent between 2015 and 2023.

What Is Diabetic Ketoacidosis And What Are Its Warning Signs?

Its symptoms can include excessive thirst, urinating frequently, stomach pain, nausea, vomiting, diarrhoea and blurred vision. More serious warning signs include deep or unusual breathing, fruity breath, extreme tiredness, sleepiness, or confusion.

Researchers said that developing an infection was the most common trigger of ketoacidosis. They also said that kidney problems, stroke and major surgery were also seen as triggers in patients who developed it.

Also read: Thailand’s HIV Cases Cross 550,000 In 2026; Over 25,000 Among 15–24s

What Are The Study's Findings?

SGLT2 inhibitors reduce blood sugar by helping the kidneys remove excess glucose through urine. They are widely used in type 2 diabetes treatment as their benefits extend to the heart and kidneys as well. Some studies have also linked them to weight loss.

However, these medicines can encourage the body to rely more heavily on fat for energy. This process can increase ketone production, increasing the risk of ketoacidosis in susceptible patients.

The study found that the risk was particularly high among people who had previously experienced ketoacidosis, had high blood sugar, were underweight, or showed signs of malnutrition.

Patients with a history of dangerously low blood sugar (hypoglycaemia) were also at increased risk.

Also read: Once-Weekly Oral Combination HIV Pill Shows Promise As Alternative to Daily Treatment

Greater Risk At The Beginning Of The Treatment

While patients faced their greatest risk during the first few months after starting an SGLT2 inhibitor, researchers found that the risk persisted for as long as they continued taking the medicine.

This finding is contradictory to previous research that has largely focused on ketoacidosis occurring soon after treatment begins.

Peter Ueda, assistant professor at the Department of Medicine at the Karolinska Institute, said the findings should not be interpreted as a reason for patients to stop their medication.

SGLT2 inhibitors provide medical benefits for many patients,” Ueda said.“Our findings are not primarily about avoiding treatment, but about improving our ability to identify high-risk patients and use these medicines more safely,” he added.

The findings can help doctors identify people who may need closer monitoring before and during treatment, particularly if they have previous ketoacidosis, are underweight or malnourished, or develop an infection.

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