Headaches are a common symptom of a stressful lifestyle, your body not feeling well and other issues. While headaches can be dealt with easily, migraines are not so easy to handle. Migraines are a type of headache that feels like severe throbbing and pulsing sensation, almost like you are hearing your own heartbeat in your brain, usually on one side of the brain. Many people believe that migraines are not that big of a deal because you just have to deal with the pain, but that is not all migraine is, some people find it very difficult to do their daily tasks as they experience dizzying spells, nausea and extreme sensitivity to light and sound! These attacks can last hours and make it difficult for people to go about their daily lives as well. While there are medications available for migraine patients, these medications need time to take effect, so you may be in a lot of pain, but there are not many quick reliefs you can have in place other than learning the symptoms of a migraine attack and taking medication before it happens. But a new approval by the FDA may change this!

The U.S. Food and Drug Administration (FDA) has approved Symbravo, a new medicine to treat acute migraine attacks in adults. This means adults can now use Symbravo to get relief from their migraine symptoms. The FDA's decision was based on the results of three big studies, called Phase 3 trials. These trials involved over 21,000 migraine attacks, so the FDA has a lot of information about how well Symbravo works and how safe it is. The FDA only approves medicines that have been shown to be both safe and effective through a thorough testing process.

Importance of New Treatment Option

"Migraine attacks can happen suddenly and really mess up people's lives. It's estimated that over 39 million people in the U.S. alone get migraines," said Herriot Tabuteau, M.D., CEO of Axsome Therapeutics told US News. This shows how common migraines are and how important it is to have good treatments. "Symbravo gives patients and doctors a new option that can quickly stop a migraine attack, keep it away, and let people get back to their normal activities, all with just one dose." Having a medicine that can give fast and long-lasting relief from migraine pain is a big deal for millions of people. This new treatment is a real step forward in how we treat migraines.

Symbravo Trial Results, How Was It Approved

The trials took place in 3 steps, the Momentum trial study focused on people whose migraines had moderate to severe pain. The results showed that a lot more people taking Symbravo felt pain-free two hours after taking the medicine compared to those who took a placebo which is a dummy pill. Even better, many people felt relief for up to 24 and even 48 hours after just one dose. This long-lasting relief is really important for people with migraines because it means they can get back to their normal lives without worrying about the pain coming back. The study also looked at how many people were free from their worst symptom, like sensitivity to light or sound, or nausea. Symbravo worked better than the placebo in this area too.

While the intercept trial looked at people who took Symbravo when their migraine pain was still mild. Even when the pain was just starting, Symbravo was effective. The results were similar to the MOMENTUM trial, with many people getting pain relief and relief from their worst symptoms. Treating migraines early is often better because it can stop the pain from getting really bad.

And lastly the Movement trial which was to see how safe the medication is when people take it regularly. This study followed 706 people who had at least two migraines a month. The most common side effects people experienced were sleepiness and dizziness. While these side effects are important to know about, the study showed that Symbravo is generally safe for people to use on a regular basis.

Prime Minister Narendra Modi, in his latest episode of Mann Ki Baat, highlighted the growing awareness of organ donations in India.

The Prime Minister lauded people who have undertaken such noble deeds.

According to the latest data from the Ministry of Health and Family Welfare, India has recorded a fourfold surge in organ transplants over the last decade. From less than five thousand in 2013, organ transplants in the country jumped to nearly 20 thousand in 2025.

“Awareness about organ donation is steadily rising in India these days. This is helping those who are in need of it. It is also strengthening medical research in the country. Many organizations and individuals are doing extraordinary work in this direction,” the PM said in the 131st episode of the monthly radio program.

The Prime Minister also paid tributes to 10-month-old Aalin Sherin Abraham, from Kerala, who lost her life in an accident but gave life to five people to become the youngest organ donor in the state.

“There is no greater sorrow for any parent than losing one’s own child. The pain of losing a very young child is deeper. Just a few days ago, we lost Aalin Sherin Abraham, a little innocent girl from Kerala. She left this world at the age of just 10 months.

PM Modi said even amidst "profound pain", Aalin's father, Arun Abraham, and mother, Sherin, decided to donate her organs.

"While on the one hand, they grieved the loss of their daughter, on the other, they were also filled with a spirit of helping others," PM Modi said.

“Aalin Sherin Abraham is no longer with us, but her name has joined the ranks of the nation's youngest organ donors,” he added.

He also mentioned the names of organ recipients -- Lakshmi Devi from Delhi, Gaurang Banerjee from West Bengal, and Ramdev Singh of Sikar, Rajasthan -- who, after receiving the transplants, got a second chance at life.

“You will come across many such inspiring examples. This proves once again that a single noble act can change the lives of countless people. I heartily commend all those who have undertaken such noble deeds,” the Prime Minister said.

Where Does India Stand In Terms Of Organ Transplants?

The National Organ and Tissue Transplant Organization (NOTTO) has recorded an unprecedented progress in organ donation, allocation, and transplantation across the country.

As per the Health Ministry, about 18 per cent of transplants are currently being performed with the organs donated from deceased donors.

In 2025 alone, more than 1,200 families came forward to donate organs of their loved ones after death. Each donor is now also a multiorgan donor, transforming the lives of many.

Since September 2023, more than 4.8 lakh citizens have registered to donate organs and tissues after death through an Aadhaar-based verification system.

Notably, India has also achieved competence in performing difficult organ transplants like the heart, lungs, and pancreas.

The country also leads the world in hand transplants and performs a greater number of hand transplants than any other country.

Prime Minister Narendra Modi, in his latest episode of Mann Ki Baat, highlighted the growing awareness of organ donations in India.

The Prime Minister lauded people who have undertaken such noble deeds.

According to the latest data from the Ministry of Health and Family Welfare, India has recorded a fourfold surge in organ transplants over the last decade. From less than five thousand in 2013, organ transplants in the country jumped to nearly 20 thousand in 2025.

“Awareness about organ donation is steadily rising in India these days. This is helping those who are in need of it. It is also strengthening medical research in the country. Many organizations and individuals are doing extraordinary work in this direction,” the PM said in the 131st episode of the monthly radio program.

The Prime Minister also paid tributes to 10-month-old Aalin Sherin Abraham, from Kerala, who lost her life in an accident but gave life to five people to become the youngest organ donor in the state.

“There is no greater sorrow for any parent than losing one’s own child. The pain of losing a very young child is deeper. Just a few days ago, we lost Aalin Sherin Abraham, a little innocent girl from Kerala. She left this world at the age of just 10 months.

PM Modi said even amidst "profound pain", Aalin's father, Arun Abraham, and mother, Sherin, decided to donate her organs.

"While on the one hand, they grieved the loss of their daughter, on the other, they were also filled with a spirit of helping others," PM Modi said.

“Aalin Sherin Abraham is no longer with us, but her name has joined the ranks of the nation's youngest organ donors,” he added.

He also mentioned the names of organ recipients -- Lakshmi Devi from Delhi, Gaurang Banerjee from West Bengal, and Ramdev Singh of Sikar, Rajasthan -- who, after receiving the transplants, got a second chance at life.

“You will come across many such inspiring examples. This proves once again that a single noble act can change the lives of countless people. I heartily commend all those who have undertaken such noble deeds,” the Prime Minister said.

Where Does India Stand In Terms Of Organ Transplants?

The National Organ and Tissue Transplant Organization (NOTTO) has recorded an unprecedented progress in organ donation, allocation, and transplantation across the country.

As per the Health Ministry, about 18 per cent of transplants are currently being performed with the organs donated from deceased donors.

In 2025 alone, more than 1,200 families came forward to donate organs of their loved ones after death. Each donor is now also a multiorgan donor, transforming the lives of many.

Since September 2023, more than 4.8 lakh citizens have registered to donate organs and tissues after death through an Aadhaar-based verification system.

Notably, India has also achieved competence in performing difficult organ transplants like the heart, lungs, and pancreas.

The country also leads the world in hand transplants and performs a greater number of hand transplants than any other country.

Women, young ones and ones holding their babies, along with some men lined up on the outskirts of Zimbabwe's capital Harare for the injections of a new HIV prevention drug. The country launched it on Thursday. This drug needs to be administered only twice a year.

Why Is This Vaccine So Important For Zimbabwe?

Zimbabwe is a country where HIV led to tens of thousands of deaths in the last two decades. It is the first country to roll out lenacapavir, which is a long-acting drug that authorities have put their hopes on to slow down the HIV infection.

Also Read: Hangover Star Ken Jeong's Wife Beats Stage 3 Breast Cancer

What Is So Special About The HIV Injections?

Clinical studies have demonstrated near-total protection for the drug and has been described as a 'turning point' for high risk groups by many experts. However, many have warned that its broad impact would require overcoming funding constraints, infrastructure gaps and the challenge of keeping patients engaged.

Immunologist at Emory University Rama Rao Amara, calls it a "wonder drug". The drug, known as lenacapavir has been approved by the Food and Drug Administration (FDA) and is made by Gilead Sciences.

How Does This Drug Differ From Earlier HIV Prevention Drugs?

In 2021, FDA approved injectable form of PrEP medication called cabotegravir, however, this required patients to take it in every two months. This was also an intramuscular dose that healthcare providers were to administer into the buttocks.

What changes with lenacapavir is its easy administration. Each dose lasts longer compared to other medications and requires to be administered twice a year.

Read: 12.4 Lakh HIV Tests In Haryana Detect 5,877 Cases

The limitation with lenacapavir is its price tag of more than $28,000 per person per year. Carmen Pérez Casas, a senior strategy leader at Unitaid, a global health initiative based in Geneva, Switzerland said, "This is unaffordable. We need to get somewhere close to what previous options cost."

However, there is hope as the researchers published an analysis in The Lancet HIV that suggested generic versions of this drug could cost a person $25 per year.

Could This Drug Reshape HIV Prevention?

At the Zimbabwe launch, Constance Mukoloka, a sex worker, was among the first beneficiaries of this roll out which has happened by donor-support across 10 African countries, as reported by PBS News.

"I am safe, I can work with confidence now," said the 27-year-old sex worker. "When I took tablets, customers would see a container of pills and leave. They would never return due to fear," she said. "They couldn't tell the difference between PrEP and treatment drugs. With the work we do, that stigma costs you money."

Daily oral PrEP has been offered in Zimbabwe for years, along with condoms, vaginal rings and shorter-acting injections. However, sticking to the regimen has been difficult, especially for people dealing with stigma or irregular daily routines.

"I work in beer halls looking for clients. Sometimes I would get drunk and forget to take my drugs," Mukoloka said. "Sometimes I would work all night and not have time. Some clients refuse protection. They say ... 'Why should I use protection when I have paid?'"