(Credit-Canva)
Headaches are a common symptom of a stressful lifestyle, your body not feeling well and other issues. While headaches can be dealt with easily, migraines are not so easy to handle. Migraines are a type of headache that feels like severe throbbing and pulsing sensation, almost like you are hearing your own heartbeat in your brain, usually on one side of the brain. Many people believe that migraines are not that big of a deal because you just have to deal with the pain, but that is not all migraine is, some people find it very difficult to do their daily tasks as they experience dizzying spells, nausea and extreme sensitivity to light and sound! These attacks can last hours and make it difficult for people to go about their daily lives as well. While there are medications available for migraine patients, these medications need time to take effect, so you may be in a lot of pain, but there are not many quick reliefs you can have in place other than learning the symptoms of a migraine attack and taking medication before it happens. But a new approval by the FDA may change this!
The U.S. Food and Drug Administration (FDA) has approved Symbravo, a new medicine to treat acute migraine attacks in adults. This means adults can now use Symbravo to get relief from their migraine symptoms. The FDA's decision was based on the results of three big studies, called Phase 3 trials. These trials involved over 21,000 migraine attacks, so the FDA has a lot of information about how well Symbravo works and how safe it is. The FDA only approves medicines that have been shown to be both safe and effective through a thorough testing process.
"Migraine attacks can happen suddenly and really mess up people's lives. It's estimated that over 39 million people in the U.S. alone get migraines," said Herriot Tabuteau, M.D., CEO of Axsome Therapeutics told US News. This shows how common migraines are and how important it is to have good treatments. "Symbravo gives patients and doctors a new option that can quickly stop a migraine attack, keep it away, and let people get back to their normal activities, all with just one dose." Having a medicine that can give fast and long-lasting relief from migraine pain is a big deal for millions of people. This new treatment is a real step forward in how we treat migraines.
The trials took place in 3 steps, the Momentum trial study focused on people whose migraines had moderate to severe pain. The results showed that a lot more people taking Symbravo felt pain-free two hours after taking the medicine compared to those who took a placebo which is a dummy pill. Even better, many people felt relief for up to 24 and even 48 hours after just one dose. This long-lasting relief is really important for people with migraines because it means they can get back to their normal lives without worrying about the pain coming back. The study also looked at how many people were free from their worst symptom, like sensitivity to light or sound, or nausea. Symbravo worked better than the placebo in this area too.
While the intercept trial looked at people who took Symbravo when their migraine pain was still mild. Even when the pain was just starting, Symbravo was effective. The results were similar to the MOMENTUM trial, with many people getting pain relief and relief from their worst symptoms. Treating migraines early is often better because it can stop the pain from getting really bad.
And lastly the Movement trial which was to see how safe the medication is when people take it regularly. This study followed 706 people who had at least two migraines a month. The most common side effects people experienced were sleepiness and dizziness. While these side effects are important to know about, the study showed that Symbravo is generally safe for people to use on a regular basis.
Credit: AI generated image
The hantavirus outbreak, which began late in April aboard the MV Hondius cruise ship, is now stable, according to the World Health Organization (WHO).
Sharing opening remarks at the 159th session of the Executive Board today, WHO Director-General Tedros Adhanom Ghebreyesus said that no new cases and deaths of the rat-borne virus have been reported.
“The hantavirus outbreak is now stable, with one new case in the past two weeks, and no new deaths since May 2,” he said.
The outbreak resulted in 12 total cases (10 confirmed, 2 probable) and 3 deaths.
“All passengers and crew remain in quarantine and under close monitoring to ensure they receive care if needed,” the WHO Chief added.
All the passengers have been repatriated and will be monitored until the quarantine period ends on June 21. The crew will also be quarantined until June 29.
A Dutch couple is believed to have been first exposed to the virus while visiting a birdwatching site in Argentina.
“There is no sign that we are seeing the start of a larger outbreak. But of course, that could change, and we urge all affected countries to continue monitoring the passengers and crew carefully. I thank the many countries involved in the response,” Tedros said.
Also read: WHO Chief Warns Ebola Epidemic ‘Outpacing Us’; India Intensifies Screening At Airports
The current outbreaks of Ebola and hantavirus remind us that the next pandemic will not wait for us, he noted, urging countries to work on making the Pandemic Agreement operational.
The WHO has confirmed that the Andes strain of hantavirus — the only strain known to spread from person to person — is behind the outbreak. The strain has no vaccine.
Meanwhile, the Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. said he signed a targeted Public Readiness and Emergency Preparedness Act declaration “to support the development and deployment of medical countermeasures related to the Andes virus” strain of hantavirus.
“This action helps remove barriers to research and response efforts while we continue monitoring the recent outbreak linked to the South Atlantic cruise ship,” Kennedy said in a statement posted to social media. “HHS is taking this situation seriously and will continue working to protect public health and support the safe development of potential treatments and countermeasures.”
As per the WHO, hantaviruses are zoonotic viruses that naturally infect rodents and are occasionally transmitted to humans.
Globally, an estimated 100,000 to 200,000 hantavirus infections occur each year. The majority of these cases are in Asia, particularly China. Most are sporadic or occur in small clusters, linked to contact with infected rodents.
Infection in people can result in severe illness and often death, although the diseases vary by type of virus and geographical location.
Notably, the WHO has not specified the type of hantavirus or syndrome in the cruise incident, but did mention respiratory risks.
The hantavirus is primarily spread by rodents through
Credit: iStock
The ongoing Ebola outbreak "is spreading rapidly" and "outpacing us", said Tedros Adhanom Ghebreyesus, Director General of the World Health Organization, today.
At the Virtual Ministerial Briefing on the Bundibugyo Ebola Outbreak today, he stated that "more than 900 suspected cases have been identified so far, including 101 confirmed cases".
Echoing concern, he noted that the epidemic is outpacing us.
"We are urgently scaling up operations, but at the moment the epidemic is outpacing us," Tedros said, adding that countries bordering the Democratic Republic of Congo, the epicenter of the outbreak, should take immediate action.
Officials informed that Uganda reported two more Ebola cases, taking its total number of confirmed cases to seven. The deadly virus has reportedly killed at least 220 people so far.
Tedros added that the "delay in detecting the outbreak means that we are now playing catch-up with a very fast-moving epidemic".
Ebola disease is a severe viral hemorrhagic fever with a high mortality rate.
Also read: Why Ebola Does Not Spread Like COVID-19: Experts Explain
The mounting cases of Ebola virus in the Democratic Republic of Congo and Uganda has kept India on alert mode.
The Union Minister of Health and Family Welfare, Jagat Prakash Nadda, today held another review meeting to check the country's preparedness and surveillance measures for Ebola disease.
“India has not reported any case of Bundibugyo Ebola disease to date," the Union Health Minister said.
The country has also issued a travel advisory for citizens to avoid non-essential travel to the Democratic Republic of the Congo, Uganda, and South Sudan.
The Union Health Ministry earlier issued Standard Operating Procedures (SOPs) on public health preparedness and response to Ebola disease, encompassing protocols for screening, quarantine, clinical management, laboratory testing, and infection prevention practices.
In addition, guidelines have been issued for hospital infection control, isolation facility preparedness, and for safe and dignified handling of human remains of Ebola patients.
Integrated Disease Surveillance Program (IDSP) units and Airport Health Organizations have been instructed to maintain heightened vigilance for unexplained febrile illness among international travelers and ensure prompt reporting and management of any suspected case.
Meanwhile, states like Maharashtra, Kerala, Andhra Pradesh, and Gujarat have intensified screening of passengers arriving from Ebola-affected countries like Uganda, Congo, and South Sudan.
The Union government has asked states to identify designated isolation facilities, arrange dedicated ambulances, and ensure availability of trained healthcare personnel, personal protective equipment (PPE), laboratory support, and critical care capacity.
An advisory is displayed at the Delhi airport by the Airport Health Organization (APHO) , advising passengers to watch out for symptoms such as:
According to the APHO, any traveler developing symptoms within 21 days of arrival should seek immediate medical care and inform authorities about their travel history.
Read More: Ebola Outbreak: University of Glasgow Researcher Explains Why Bundibugyo Virus Is Concerning
Even though the new Bundibugyo strain has no vaccine or antiviral, the WHO has recommended prioritizing two monoclonal antibodies for clinical trials.
"We are also recommending the evaluation of the antiviral obeldesivir in a clinical trial as post-exposure prophylaxis for people who are high-risk contacts," the WHO chief said.
This clinical trial is now being developed jointly with Africa CDC and the Collaborative Open Research Consortium on filoviruses, he noted.
Credit: AI generated image
As Delhi and most of North India continue to face rising temperatures, doctors have raised concerns over worsening air pollution, warning that the combination is placing severe stress on the human body, even among otherwise healthy individuals.
HealthandMe spoke to experts to understand how the overlap of heatwaves and polluted air can affect health.
According to experts, extreme heat and pollution together are no longer just an environmental issue, but are emerging as a serious urban health emergency.
Also Read: AYUSH Ministry Shares Yoga, Ayurveda Tips To Beat Heatwave Stress
Dr. Amit Kumar Mandal, Senior Director - Pulmonology at Paras Health, explained that extreme heat combined with pollution forces multiple organs to work harder simultaneously.
“People often think heatwaves only affect the skin or cause dehydration, but when extreme heat combines with high pollution levels, the body starts functioning as if it is constantly under attack,” he said.
The expert explained that "the lungs are forced to work harder to filter hot, polluted air, while the heart simultaneously struggles to regulate body temperature. This invisible overload can quietly trigger inflammation, breathing distress, sudden BP fluctuations, and cardiac strain, even in people who otherwise consider themselves healthy".
Also read: What Is The Best Low-Cost Solution For Panic Attacks?
Dr. Amit further noted that the subtle symptoms in the beginning often go unnoticed, making the combination even more dangerous.
The symptoms increasingly being seen during such weather conditions include
“Heat and pollution together are no longer just an environmental issue; they are emerging as a serious urban health emergency. Preventive care during summers now has to go beyond avoiding the sun; people need to actively protect their respiratory and cardiovascular health as well,” Dr. Amit told HealthandMe .
Dr. Rahul Punj, Senior Consultant - Internal Medicine at Yatharth Super Speciality Hospital, told HealthandMe that prolonged exposure to high temperatures and poor air quality can affect multiple systems in the body.
“Rising heat and increasing pollution levels are becoming major health concerns, especially in urban areas. Prolonged exposure to extreme temperatures and poor air quality can lead to dehydration, heat exhaustion, breathing difficulties, allergies, skin issues, and can even worsen heart and lung diseases. Children, elderly people, pregnant women, outdoor workers, and patients with asthma, COPD, or other chronic illnesses need to be extra cautious during this period,” he said.
Read More: Ebola Cases Cross 900, Death Toll Tops 200; 10 Countries On High Alert
Dr. Rahul advised people to take preventive measures seriously during heatwave conditions. Preventive measures that can help reduce health risks include:
Residents in Delhi continue to struggle against soaring temperatures and blazing sunshine. The India Meteorological Department (IMD) has issued a yellow alert for the next three days, warning of continued heatwave conditions along with strong surface winds during the afternoons and evenings.
The maximum temperatures are expected to increase by a further 1°C-2°C within the next 24 hours and are forecast to stay high until May 27.
The national capital recorded a maximum temperature of 43.6 degrees Celsius on Sunday, around 3.4 degrees above the seasonal average. The minimum temperature settled at 28.4 degrees Celsius in the morning, nearly two degrees above normal.
Last week, the Commission for Air Quality Management (CAQM) invoked Stage 1 of the Graded Response Action Plan (GRAP) across Delhi-NCR after the city’s air quality slipped into the ‘poor’ category.
© 2024 Bennett, Coleman & Company Limited