Headaches are a common symptom of a stressful lifestyle, your body not feeling well and other issues. While headaches can be dealt with easily, migraines are not so easy to handle. Migraines are a type of headache that feels like severe throbbing and pulsing sensation, almost like you are hearing your own heartbeat in your brain, usually on one side of the brain. Many people believe that migraines are not that big of a deal because you just have to deal with the pain, but that is not all migraine is, some people find it very difficult to do their daily tasks as they experience dizzying spells, nausea and extreme sensitivity to light and sound! These attacks can last hours and make it difficult for people to go about their daily lives as well. While there are medications available for migraine patients, these medications need time to take effect, so you may be in a lot of pain, but there are not many quick reliefs you can have in place other than learning the symptoms of a migraine attack and taking medication before it happens. But a new approval by the FDA may change this!

The U.S. Food and Drug Administration (FDA) has approved Symbravo, a new medicine to treat acute migraine attacks in adults. This means adults can now use Symbravo to get relief from their migraine symptoms. The FDA's decision was based on the results of three big studies, called Phase 3 trials. These trials involved over 21,000 migraine attacks, so the FDA has a lot of information about how well Symbravo works and how safe it is. The FDA only approves medicines that have been shown to be both safe and effective through a thorough testing process.

Importance of New Treatment Option

"Migraine attacks can happen suddenly and really mess up people's lives. It's estimated that over 39 million people in the U.S. alone get migraines," said Herriot Tabuteau, M.D., CEO of Axsome Therapeutics told US News. This shows how common migraines are and how important it is to have good treatments. "Symbravo gives patients and doctors a new option that can quickly stop a migraine attack, keep it away, and let people get back to their normal activities, all with just one dose." Having a medicine that can give fast and long-lasting relief from migraine pain is a big deal for millions of people. This new treatment is a real step forward in how we treat migraines.

Symbravo Trial Results, How Was It Approved

The trials took place in 3 steps, the Momentum trial study focused on people whose migraines had moderate to severe pain. The results showed that a lot more people taking Symbravo felt pain-free two hours after taking the medicine compared to those who took a placebo which is a dummy pill. Even better, many people felt relief for up to 24 and even 48 hours after just one dose. This long-lasting relief is really important for people with migraines because it means they can get back to their normal lives without worrying about the pain coming back. The study also looked at how many people were free from their worst symptom, like sensitivity to light or sound, or nausea. Symbravo worked better than the placebo in this area too.

While the intercept trial looked at people who took Symbravo when their migraine pain was still mild. Even when the pain was just starting, Symbravo was effective. The results were similar to the MOMENTUM trial, with many people getting pain relief and relief from their worst symptoms. Treating migraines early is often better because it can stop the pain from getting really bad.

And lastly the Movement trial which was to see how safe the medication is when people take it regularly. This study followed 706 people who had at least two migraines a month. The most common side effects people experienced were sleepiness and dizziness. While these side effects are important to know about, the study showed that Symbravo is generally safe for people to use on a regular basis.

The United States has issued a travel advisory against global polio. International travel often comes with vaccine reminder and health checks to stay safe. The Centers for Disease Control and Prevention (CDC) issued a Level 2 travel advisory for certain international destinations with circulating poliovirus. The CDC has asked travellers to ensure they are up to date on their polio vaccines.

Also Read: 500 Girls In Rajasthan Receive HPV Vaccine In First Five Days Of Prevention Drive

The Destination list for global polio travel notice includes:

• Afghanistan
• Algeria
• Angola
• Benin
• Burkina Faso
• Cameroon
• Central African Republic
• Chad
• Côte d'Ivoire (Ivory Coast)
• Democratic Republic of the Congo
• Djibouti
• Ethiopia
• Finland
• Germany
• Ghana
• Guinea
• Israel
• the West Bank and Gaza
• Niger
• Nigeria
• Pakistan
• Papua New Guinea
• Poland
• Republic of South Sudan
• Senegal
• Somalia
• Spain
• Sudan
• Tanzania, including Zanzibar
• United Kingdom, including England, Scotland, Wales, and Northern Ireland
• Yemen
• Zimbabwe

The CDC issued a 'Level 2' advisory, which means to 'practice enhanced precautions'.

Also Read: The Hidden Cost of Extreme Fitness On Women’s Bodies | Women's Day Special

The advisory suggests that children and adults should be up to date on their routine polio vaccines. Travelers are also asked to get an inactivated polio vaccine booster if they are going to the destination that has circulating poliovirus, or have completed their routine polio vaccine series; and have not already received one adult booster dose.

Types Of Notices Issued By CDC

The CDC issues four different types of notices based on the gravity of the disease spread.

Level 1 : Practice Usual Precautions

Practice usual precautions for this destination, as described in the Travel Health Notice and/or on the destination page.

Level 2: Practice Enhanced Precautions

Practice enhanced precautions for this destination. The Travel Health Notice describes additional precautions or defines a specific population at risk.

Level 3: Reconsider Nonessential Travel

Reconsider nonessential travel to this destination. The outbreak or event poses risk to travelers because limited precautions are available.

Level 4: Avoid All Travel

Avoid travel to this destination unless traveling for humanitarian aid or emergency response; there is an extreme health risk for travelers and no available precautions.

What Is Polio?

The World Health Organization (WHO) notes that it is a highly infectious disease caused by a virus that invades the nervous system and can cause total paralysis in matter of hours. The virus is transmitted by person to person spread mainly through the fecal-oral route, or less frequently, by a common vehicle, which could be either from contaminated food or water. The virus also multiplies in the intestine.

The National Institute of Health (NIH), US, notes that the virus responsible for causing Polio belongs to the Picornaviridae family.

As per the WHO, the common Polio symptoms are:

• Fever
• Fatigue
• Headache
• Vomiting
• Stiffness of the neck a
• Pain in the limbs

How Does Polio Spread?

Polio is mainly transmitted through the faecal-oral route, meaning it spreads when a person consumes food or water contaminated with the virus. It can also spread through close contact with an infected individual. The poliovirus lives in the throat and intestines of those infected, and poor sanitation, unsafe water, and inadequate hygiene greatly increase the risk of transmission, especially in communities with limited access to clean facilities.

In severe cases, polio can lead to acute flaccid paralysis, which may affect the diaphragm and throat muscles, making it difficult to breathe or swallow. Since there is no cure for polio, prevention remains the only line of defence. Raising awareness about polio vaccination is therefore essential to protect individuals, especially children, from this potentially life-threatening disease.

500 girls have received the Human papillomavirus (HPV) vaccines in the first five days of launching the cervical cancer prevention drive. A senior officer, as also reported by TOI noted that misinformation and lack of awareness could lead to a lower number of girls showing up. This is why, while the initial response is encouraging, logistics are still need to be figured out, including identification of session sites and to widen coverage and counter doubts that surround the vaccine. "The HPV vaccine helps prevent cervical caner, one of the most common cancers among women in the country. Addressing public concerns is crucial for the program's success," said the official.

Also Read: US Issues Travel Advisory For International Travelers Against Global Polio

Health officials along with public health experts will be conducting interactive sessions on social media across districts on Thursday. In Sikar, a dedicated platform will also allow experts to respond to the questions directly on HPV infections, vaccine safety, eligibility and benefits.

As of now, the program allows a single vaccine dose for girls who have completed 14 years and are yet to turn 15. As per the Health Department, around 8.32 lakh girls in Rajasthan are eligible for the vaccine annually.

Nationwide Free HPV Vaccine Drive

Prime Minister Narendra Modi on February 28 launched the nationwide Human Papillomavirus (HPV) vaccination campaign for girls aged 14 years from Rajasthan's Ajmer.

The initiative marks a decisive step towards eliminating cervical cancer through timely HPV vaccination. Cervical cancer remains the second most common cancer among women in India. Nearly 80,000 new cases and over 42,000 deaths are reported annually in the country.

Read: PM Modi Launches Nationwide Free HPV Vaccination Drive; A Landmark Step, Says WHO

"Today, I have had the opportunity to launch the HPV vaccine campaign from Ajmer. This campaign is an important step towards empowering women and daughters of this country,” PM Modi said.

“For us, this was a sensitive issue tied to the insult of our sisters and daughters, one that made them ill. That is why we resolved it at a crucial turning point in their mission,” he added.

The World Health Organization has also lauded India's mission to launch the HPV vaccine and prevent the risk of cervical cancer.

“We are leaving no stone unturned to ensure that the daughters of the country are healthy and prosperous. The objective of this initiative is the prevention of cervical cancer," the Prime Minister, earlier wrote in a post on social media platform X.

Who Can Avail The Nationwide Free HPV Vaccination Drive?

The vaccine is most effective when it is administered before exposure to HPV and before becoming sexually active. Young women aged 9 to 14 years show vaccine effectiveness of 74 to 93 per cent and this decreases with age.

Read: India Launches Nationwide Free HPV Vaccine For Adolescent Girls - Why Should Every Woman Consider It?

Girls aged 9 to 14 should get two doses of the vaccine in 6 to 12 months apart

Women aged 15 to 26 years can get three doses in 0, 2, and 6 months apart

Adults aged 27 to 45 must get it after consultation with their healthcare provider

Chile became the first country in the Americas to be verified by the World Health Organization (WHO) for the elimination of leprosy. WHO with Pan American Health Organization (PAHO), congratulated Chile for becoming the first country in the Americas and second globally to eliminate leprosy.

Leprosy (Hansen disease) was historically recorded in Chile at the end of the 19th century on Rapa Nui (Easter Island). The disease was limited in mainland Chile, with sporadic introductions, contained through isolation and treatment measures in the Island, where the last secondary cases were managed by the late 1990s.

Since then, Chile did not report locally acquired case of leprosy in more than 30 years. The last locally acquired case was detected in 1993. However, the disease was never removed from public health agenda and remained a notifiable condition and monitored through mandatory reporting, surveillance and continuous clinical readiness.

Chile Makes History In Health Care

Dr Tedros Adhanom Ghebreyesus, WHO Director-General said, “This landmark public health achievement is a powerful testament to what leadership, science, and solidarity can accomplish. Chile’s elimination of leprosy sends a clear message to the world: with sustained commitment, inclusive health services, integrated public health strategies, early detection and universal access to care, we can consign ancient diseases to history.”

PAHO Director Dr Jarbas Barbosa said, "Chile’s achievement demonstrates that eliminating leprosy is achievable and requires building strong systems that can detect, respond to, and provide comprehensive care for people affected by the disease, including those living with chronic disabilities. Being the first country in the Americas to be confirmed as eliminating leprosy sends a powerful message to the Region – that diseases strongly linked to groups living in vulnerable conditions can be eliminated, contributing to interrupt the vicious circle between disease and poverty.”

How Did Chile Achieve Elimination of Leprosy?

As per WHO between 2012 and 2023, Chile reported 47 cases nationwide, none of which were locally acquired.

WHO notes that Chile's integrated model ensures early detection and comprehensive care: primary care centers serve as the entry point for suspected cases, with timely referrals to specialized dermatology services for diagnosis, treatment, and follow-up. Clinicians receive training aligned with WHO's Towards zero leprosy strategy. The system prioritizes early intervention, disability prevention, and holistic care, including physiotherapy and rehabilitation services, ensuring that anyone affected by leprosy receives continuous support for both acute and long-term health needs to promote full recovery and social inclusion.

What Is Leprosy?

Leprosy is also known as Hansen disease. It is a chronic infectious disease that is caused by bacterium Mycobacterium leprae. It affects the skin, peripheral nerves, upper respiratory tract mucosa and eyes.

If it is not treated timely, it could lead to permanent nerve damage, disabilities and social stigma. However, the condition is fully curable with multidrug therapy and early detection could prevent further complications.