FDA Has Approved A New Medication Treatment For Migraines In Adults

Updated Feb 6, 2025 | 05:09 PM IST

SummaryMany people use the terms ‘migraine’ and ‘headache’ interchangeably. This leads many people to believe that migraines are not as serious as people make them out to be, and that cannot be more wrong, migraines have a major effect on a person’s lifestyle and the new approved medication may prove to be a great relief!
(Credit-Canva)

(Credit-Canva)

Headaches are a common symptom of a stressful lifestyle, your body not feeling well and other issues. While headaches can be dealt with easily, migraines are not so easy to handle. Migraines are a type of headache that feels like severe throbbing and pulsing sensation, almost like you are hearing your own heartbeat in your brain, usually on one side of the brain. Many people believe that migraines are not that big of a deal because you just have to deal with the pain, but that is not all migraine is, some people find it very difficult to do their daily tasks as they experience dizzying spells, nausea and extreme sensitivity to light and sound! These attacks can last hours and make it difficult for people to go about their daily lives as well. While there are medications available for migraine patients, these medications need time to take effect, so you may be in a lot of pain, but there are not many quick reliefs you can have in place other than learning the symptoms of a migraine attack and taking medication before it happens. But a new approval by the FDA may change this!

The U.S. Food and Drug Administration (FDA) has approved Symbravo, a new medicine to treat acute migraine attacks in adults. This means adults can now use Symbravo to get relief from their migraine symptoms. The FDA's decision was based on the results of three big studies, called Phase 3 trials. These trials involved over 21,000 migraine attacks, so the FDA has a lot of information about how well Symbravo works and how safe it is. The FDA only approves medicines that have been shown to be both safe and effective through a thorough testing process.

Importance of New Treatment Option

"Migraine attacks can happen suddenly and really mess up people's lives. It's estimated that over 39 million people in the U.S. alone get migraines," said Herriot Tabuteau, M.D., CEO of Axsome Therapeutics told US News. This shows how common migraines are and how important it is to have good treatments. "Symbravo gives patients and doctors a new option that can quickly stop a migraine attack, keep it away, and let people get back to their normal activities, all with just one dose." Having a medicine that can give fast and long-lasting relief from migraine pain is a big deal for millions of people. This new treatment is a real step forward in how we treat migraines.

Symbravo Trial Results, How Was It Approved

The trials took place in 3 steps, the Momentum trial study focused on people whose migraines had moderate to severe pain. The results showed that a lot more people taking Symbravo felt pain-free two hours after taking the medicine compared to those who took a placebo which is a dummy pill. Even better, many people felt relief for up to 24 and even 48 hours after just one dose. This long-lasting relief is really important for people with migraines because it means they can get back to their normal lives without worrying about the pain coming back. The study also looked at how many people were free from their worst symptom, like sensitivity to light or sound, or nausea. Symbravo worked better than the placebo in this area too.

While the intercept trial looked at people who took Symbravo when their migraine pain was still mild. Even when the pain was just starting, Symbravo was effective. The results were similar to the MOMENTUM trial, with many people getting pain relief and relief from their worst symptoms. Treating migraines early is often better because it can stop the pain from getting really bad.

And lastly the Movement trial which was to see how safe the medication is when people take it regularly. This study followed 706 people who had at least two migraines a month. The most common side effects people experienced were sleepiness and dizziness. While these side effects are important to know about, the study showed that Symbravo is generally safe for people to use on a regular basis.

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US FDA Asks Drugmakers To Set Time Limits For Antibiotic Use In Livestock

Updated Feb 18, 2026 | 11:46 AM IST

SummaryThe US FDA issued a nonbinding guidance asking veterinary drugmakers to define a time duration of antibiotic use to treat, control, and prevent bacterial infections in livestock. The guidance is aimed at curbing the rising risk of antimicrobial resistance.
US FDA Asks Drugmakers To Set Time Limits For Antibiotic Use In Livestock

Credit: Canva

The US Food and Drug Administration (FDA) has issued new guidance urging veterinary drug makers to define the duration of antibiotic use in livestock.

The February 2026 guidance, published by the FDA’s Center for Veterinary Medicine (CVM), aims to mitigate the development of antimicrobial resistance and protect public health. It is consistent with previous recommendations by the federal agency that promoted the judicious use of medically important antimicrobial drugs in animals.

The FDA said that the guidance is intended for sponsors of approved new animal drug applications (NADAs) and abbreviated new animal drug applications (ANADAs) containing antimicrobial drugs.

The guidance provides recommendations on how to add duration limits to medically important antibiotics used in or on the medicated feed of food-producing animals.

"The framework outlined in this guidance is intended to facilitate voluntary changes to have all medically important antimicrobial new animal drugs administered in alignment with the principles of judicious use,” the FDA said.

"This guidance provides specific recommendations on how sponsors may facilitate changes to the approved conditions of use of affected products in support of ongoing efforts to mitigate the development of antimicrobial resistance,” it added.

The New FDA Recommendations

Currently, no limit has been set for the approved treatment in food-producing animals. As a result, farmers can use the antibiotics in animal feed for extended periods of time.

The proposed guidelines for “appropriately defined duration of use” labelling will ensure that the drug is used only when animals need it.

The regulator also called the industry to “revise the labeling to include appropriate criteria regarding when to begin and end feeding of the antimicrobial drug.”

The nonbinding guidance also suggests sponsors avoid instructions like “feed until market weight” to define the duration of use.

"The scope of this guidance is limited to those drugs that are approved for use in or on animal feed because all the approved uses of medically important antimicrobial drugs in other (non-feed) dosage forms already have appropriately defined durations of use," the FDA said.

Why Misuse of Antibiotics In Animals Is A Concern

Antibiotic use in livestock and poultry globally is intended to treat, control, and prevent bacterial infections.

However, their overuse and misuse in food-animal production threaten both animal and human health. It is because these promote the emergence and spread of antimicrobial resistance (AMR).

AMR in livestock is a major driver of the 700,000 to over 1 million annual human deaths linked to drug-resistant infections globally.

With roughly 70 per cent of global antibiotics used in agriculture, this misuse contributes to food-borne resistant pathogens and is projected to drive up to 10 million annual human deaths by 2050, as per the World Organisation for Animal Health.

FDA On Antibiotic Use In Livestock

The 2017 guidance issued by the FDA limited the over-the-counter use of medically important antibiotics on livestock.

It also required a prescription and veterinary oversight for all antibiotic use.

Later in 2018, the CVM called for all antibiotics used in the feed and drinking water of food -producing animals to have “an appropriately targeted duration of use”.

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UK Faces Shortage Of This Common Pain Medicine Till June

Updated Feb 18, 2026 | 09:26 AM IST

SummaryPrescription-strength co-codamol will remain in short supply until June due to delays importing key ingredients from India. Patients are being told to taper doses while authorities coordinate alternatives, though health boards warn substitutes cannot meet demand fully.
UK To Face Shortage Of This Common Pain Medicine Till June

Credits: Canva

A shortage of prescription-strength co-codamol is set to continue until at least June, leaving thousands of chronic pain patients across the UK uncertain about how they will manage daily symptoms. The Scottish government has confirmed limited availability of the strongest 30/500mg tablets, while health boards warn alternative medicines may not fully cover demand.

The shortage is linked to delays in authorization by the Indian government for exporting key codeine-based ingredients needed to manufacture the drug.

Patients Told To Taper Use

Many patients say they first learned of the disruption through calls from local health services. Some have already been advised to slowly reduce their dose to avoid withdrawal symptoms.

Jocelin Harrison, who has relied on the medication for more than three decades after five spinal surgeries, said she was contacted by NHS Lanarkshire and instructed to cut down gradually.

“The only advice I’ve been given so far was to reduce the tablets and try to manage my withdrawal symptoms,” she said, as reported by the BBC.

“I was not offered any other advice or possible replacement pain killers and it’s a great worry for me and other chronic pain sufferers throughout Scotland and the UK.”

Doctors warn that abruptly stopping co-codamol can trigger headaches, nausea, sweating and a sudden increase in pain, particularly for long-term users.

Why Does This Drug Matter So Much?

Co-codamol combines paracetamol with the opioid codeine and is commonly prescribed after surgery or for persistent musculoskeletal conditions. It comes in three strengths: 8mg, 15mg and 30mg of codeine with 500mg paracetamol.

The lowest strength is available over the counter, but the stronger forms require a prescription and are widely used by patients with chronic pain. Because codeine can cause dependence, tapering rather than stopping suddenly is considered essential.

Health boards say supplies of alternative strengths are also limited, making it difficult to simply switch everyone onto another version.

Guidance issued locally states patients, except those undergoing cancer treatment, should gradually reduce usage until stopping completely. No new patients will be started on the medication until supplies stabilize.

What Are The Alternatives?

NHS Grampian has urged pharmacists to prioritize existing stock carefully. However, it stopped short of telling patients to immediately begin cutting back, highlighting variation in local guidance.

Officials acknowledge substitutes exist, but warn they cannot meet the expected rise in demand from patients switching medicines.

Authorities Now Work On Solution

Scotland’s chief pharmaceutical officer Alison Strath said the issue ultimately sits with UK-wide medicine supply systems but confirmed discussions are ongoing.

“Supply issues are expected until June 2026 and we are in regular contact with the UK government to seek assurances they are doing all they can to resolve this,” she said, adding that affected patients will be contacted directly about alternative treatment options.

The UK Department of Health and Social Care said most medicines remain readily available and manufacturers are working to restore production.

The shortage highlights the global nature of generic drug manufacturing. Medicines such as co-codamol 30/500mg are typically produced using ingredients sourced from India and China, meaning regulatory or production delays overseas can quickly affect patients at home.

For now, patients are being urged not to contact GP practices unless advised and to wait for further instructions from their health providers.

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Measles Outbreak In UK: Virus Spreads Among Unvaccinated Children In London

Updated Feb 18, 2026 | 07:11 AM IST

SummaryNorth-east London measles outbreak mainly affects unvaccinated children, with 96 cases in England and 34 in low-coverage Enfield. Most patients are under ten, as declining MMR uptake nationwide drives renewed vaccination urgency across communities.
Measles Outbreak In UK: Virus Spreads Among Unvaccinated Children In London

Credits: Canva

Measles Outbreak In UK: A measles outbreak has been confirmed in London's north east area, noted the BMJ. As per the medical journal, the outbreak is among the unvaccinated children. The medical journal also noted that there have been 96 laboratory confirmed cases of measles in England between January 1 to February 9, 2026 and more than a third, which is 34 cases are from Enfield. BMJ also noted that Enfield is also the area with lowest vaccination rates.

As per the data by the UK Health Security Agency or the UKHSA, only 64.3% of 5 year-olds Enfield received both doses of the measles, mumps, and rubella or the MMR vaccine in 2024 and 2025. The majority (74 of 96, 77%) of measles cases confirmed in the UK so far this year were in children aged 10 and under. Some 64% of cases have been in London, 26% in the West Midlands, and 4% in the East Midlands.

Read: Unique Symptoms Of Measles In 2026 And How Long Does The Infection Last?

Measles Outbreak In UK: Previous Cases And How It Made A Comeback

Last month, the World Health Organization revoked the United Kingdom’s measles elimination status after the virus was found to be circulating continuously for over a year.

In 2025, a child in Liverpool died after contracting measles, prompting renewed pressure on the NHS and government to address its return. England recorded 959 laboratory-confirmed cases that year. Although lower than the 2,911 cases in 2024, it still marked the highest annual total since 2012.

Vaccine uptake has steadily declined over the past 12 years. Only 84.4% of children in the UK receive both doses of the MMR vaccine by age five, far below the 95% coverage needed for herd immunity.

Why Has Measles Return To The UK?

In late 2023, measles outbreaks were reported in the UK, which led to a surge in cases in 2024. Vaccination uptake at the end of 2024 was 92% for the first dose, however, for the second dose, it was below 82%.

Dr Vanessa Saliba, consultant epidemiologist at UKHSA said, "Infections can return quickly when childhood vaccine uptake falls - measles elimination is only possible if all eligible children receive two MMRV doses before school. The NHS is making vaccination easier, including offering the second MMRV dose earlier at a new 18-month appointment to boost uptake and support elimination goals."

Read: UK Loses Measles Elimination Status: Why Is This Disease Making A Comeback?

She also noted that children and adults must get vaccinated as NHS also offers catch-up jabs.

Dr Baharat Pankhania, from the University of Exeter, as reported by the BBC said, "Measles is an infection that can be prevented by vaccine - and it's extremely concerning that in the UK we now have pockets of low or no vaccine uptake. We urgently need to remedy this situation." Pankhania also noted that there is a need to make the access to GPs easier, and for an effort that could immunize babies in their homes and counter wrong information around vaccine safety.

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