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Headaches are a common symptom of a stressful lifestyle, your body not feeling well and other issues. While headaches can be dealt with easily, migraines are not so easy to handle. Migraines are a type of headache that feels like severe throbbing and pulsing sensation, almost like you are hearing your own heartbeat in your brain, usually on one side of the brain. Many people believe that migraines are not that big of a deal because you just have to deal with the pain, but that is not all migraine is, some people find it very difficult to do their daily tasks as they experience dizzying spells, nausea and extreme sensitivity to light and sound! These attacks can last hours and make it difficult for people to go about their daily lives as well. While there are medications available for migraine patients, these medications need time to take effect, so you may be in a lot of pain, but there are not many quick reliefs you can have in place other than learning the symptoms of a migraine attack and taking medication before it happens. But a new approval by the FDA may change this!
The U.S. Food and Drug Administration (FDA) has approved Symbravo, a new medicine to treat acute migraine attacks in adults. This means adults can now use Symbravo to get relief from their migraine symptoms. The FDA's decision was based on the results of three big studies, called Phase 3 trials. These trials involved over 21,000 migraine attacks, so the FDA has a lot of information about how well Symbravo works and how safe it is. The FDA only approves medicines that have been shown to be both safe and effective through a thorough testing process.
"Migraine attacks can happen suddenly and really mess up people's lives. It's estimated that over 39 million people in the U.S. alone get migraines," said Herriot Tabuteau, M.D., CEO of Axsome Therapeutics told US News. This shows how common migraines are and how important it is to have good treatments. "Symbravo gives patients and doctors a new option that can quickly stop a migraine attack, keep it away, and let people get back to their normal activities, all with just one dose." Having a medicine that can give fast and long-lasting relief from migraine pain is a big deal for millions of people. This new treatment is a real step forward in how we treat migraines.
The trials took place in 3 steps, the Momentum trial study focused on people whose migraines had moderate to severe pain. The results showed that a lot more people taking Symbravo felt pain-free two hours after taking the medicine compared to those who took a placebo which is a dummy pill. Even better, many people felt relief for up to 24 and even 48 hours after just one dose. This long-lasting relief is really important for people with migraines because it means they can get back to their normal lives without worrying about the pain coming back. The study also looked at how many people were free from their worst symptom, like sensitivity to light or sound, or nausea. Symbravo worked better than the placebo in this area too.
While the intercept trial looked at people who took Symbravo when their migraine pain was still mild. Even when the pain was just starting, Symbravo was effective. The results were similar to the MOMENTUM trial, with many people getting pain relief and relief from their worst symptoms. Treating migraines early is often better because it can stop the pain from getting really bad.
And lastly the Movement trial which was to see how safe the medication is when people take it regularly. This study followed 706 people who had at least two migraines a month. The most common side effects people experienced were sleepiness and dizziness. While these side effects are important to know about, the study showed that Symbravo is generally safe for people to use on a regular basis.
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More than a year after Dawson’s Creek star James Van Der Beek revealed that he had been diagnosed with stage 3 colorectal cancer, the actor has shared a new update on how the illness has changed his outlook on life in unexpected ways. Speaking to host Craig Melvin on the December 19 episode of Today, James reflected on the moment he first heard the diagnosis.
“As soon as I found out, I remember thinking, ‘This might end up being the best thing that ever happened to me,’” he said. “There was this quiet voice in my head telling me that this diagnosis would push me to make changes I would never have made otherwise.”
As James Van Der Beek opens up about his health journey, many are asking: what kind of cancer was he diagnosed with?
James Van Der Beek was diagnosed with stage 3 colorectal cancer after he began noticing changes in his bowel habits in the summer of 2023. At first, he brushed off the symptoms, assuming they were linked to his coffee intake. However, when the changes did not go away, he decided to consult a doctor.
A colonoscopy later confirmed the cancer diagnosis. The news came as a shock, especially since Van Der Beek had no known family history of colorectal cancer and believed he was in excellent health due to his active lifestyle and balanced diet.
Colorectal cancer develops in the colon or rectum and often begins as small, non-cancerous growths known as polyps. Over time, some of these polyps can become cancerous, interfering with digestion and the body’s ability to process waste.
It is one of the more common forms of cancer and can be difficult to detect early because symptoms may not appear right away. When they do, they often include blood in the stool, persistent changes in bowel habits, abdominal discomfort, and unexplained weight loss. According to the Mayo Clinic, early screening plays a critical role in detecting the disease when it is most treatable, and lifestyle choices can significantly influence risk and outcomes.
As colorectal cancer often shows no symptoms in its early stages, routine screening is essential. Colonoscopies allow doctors to spot and remove precancerous polyps and detect cancer before it spreads. Early intervention has been shown to lower both the number of cases and deaths associated with the disease.
Data from the CDC highlights the importance of early detection, with survival rates varying widely by stage. While stage I colorectal cancer has a five-year survival rate of about 91 percent, that number drops sharply to around 14 percent for stage IV cases, according to the American Cancer Society. Health experts recommend beginning regular screening at age 45, or earlier for people with higher risk factors. Colonoscopy remains the most effective screening tool, as it examines the entire colon and allows for immediate removal of suspicious growths.
James Van Der Beek’s outlook following his stage 3 colorectal cancer diagnosis has been described as cautiously hopeful. His cancer was identified while still localized, a category associated with a significantly higher survival rate. According to the American Cancer Society, localized colorectal cancer has a five-year survival rate of approximately 91 percent.
James Van Der Beek has chosen not to share detailed information about the specific treatments he has received for his stage 3 colorectal cancer. In general, treatment for this stage of the disease typically involves surgery followed by chemotherapy, and in some cases, radiation therapy.
Nutritional support also plays an important role, particularly because colorectal cancer and its treatments can affect digestion. While Van Der Beek has kept the details private, he has emphasized that he is actively addressing his diagnosis and prioritizing his overall health as part of his recovery.
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President Donald Trump on Thursday signed an executive order aimed at speeding up the reclassification of cannabis, a move that would allow the Food and Drug Administration to more closely examine its potential medical uses. The order states that the administration’s policy is to expand research on medical marijuana and CBD so patients and doctors have clearer, evidence-based guidance.
It also stresses the need to narrow the gap between widespread use and limited scientific understanding of possible benefits and risks, according to NBC News. Under the proposed change, cannabis would be moved to Schedule III, placing it in the same category as certain commonly prescribed pain medicines, including Tylenol with codeine.
President Donald Trump has signed an executive order that marks one of the most notable shifts in U.S. marijuana policy in decades. On December 18, he instructed federal agencies to stop treating marijuana as a Schedule I substance, a category reserved for drugs considered highly dangerous, such as heroin, LSD, and ecstasy.
The Drug Enforcement Administration defines Schedule I drugs as having no accepted medical use and a high likelihood of abuse. Trump directed that marijuana instead be placed under Schedule III, which the DEA describes as substances with recognized medical uses and a moderate to low risk of physical or psychological dependence. If implemented, this change would move marijuana away from the same legal framework as heroin and LSD and align it more closely with medicines that have established therapeutic value, such as certain acetaminophen and codeine combinations.
Schedule III drugs are regulated substances that are permitted for specific medical purposes under federal law. While their manufacture, distribution, and use are tightly controlled, they can be prescribed by licensed healthcare professionals. These rules also spell out penalties for illegal trafficking. Examples of Schedule III drugs include ketamine, anabolic steroids, and some acetaminophen-codeine medications.
Marijuana has long been listed as a Schedule I drug, a classification that assumes it is highly dangerous, addictive, and lacking medical value. Reclassifying it would shift cannabis into a category that allows lawful medical prescribing.
Marijuana has remained a Schedule I substance since the passage of the Controlled Substances Act in 1970, according to CBS News.
In the United States, Schedule III drugs are recognized for medical use and are considered less likely to be abused than Schedule I or II substances, though they may still cause moderate physical or high psychological dependence. This group includes anabolic steroids, ketamine, certain opioid combinations containing codeine or hydrocodone, such as Tylenol with Codeine, and barbiturates like pentobarbital. These medications are subject to strict rules around prescribing, dispensing, and storage to balance their medical benefits with the risk of misuse.
Once the reclassification is finalized, it is expected to make research easier by reducing funding and regulatory barriers for clinical trials. Pharmaceutical companies would also find it simpler to seek FDA approval for cannabis-based medicines. Because marijuana has been listed as Schedule I, many drug makers have avoided pursuing trials due to heavy bureaucracy and high costs. Moving it to Schedule III would lower these hurdles and allow the FDA to properly study its medical potential. This could eventually expand access to cannabis-based treatments for groups such as seniors and veterans, regardless of differing state laws.
Although the change would not legalize marijuana outright, it could bring meaningful practical effects, including clearer medical access and fewer legal uncertainties for consumers and businesses. Trump also made clear that he does not support recreational legalization. He warned that using powerful controlled substances for non-medical reasons is unsafe and said that unless a doctor recommends a drug for medical purposes, people should avoid using it, according to NBC News.
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Life saving blood transfusion for thalassemia left four children HIV-positive, in India's Madhya Pradesh. The children are now confronted with lifetime illness, social stigma, and uncertainty.
The children had thalassemia, which is a genetic blood disorder that requires regular transfusion to manage severe anemia and sustain life. The authorities of central state of Madhya Pradesh, on Wednesday, said that five children with thalassemia, aged three to 15 have tested positive for HIV. Out of the five children, one of them had both of their parents were HIV positive. This has prompted concerns over blood transfusion practices and a committee has now been set up to investigate these cases.
Read: How Widespread Is Thalassemia In India—And What Can Be Done?
The families of the patients come from Satna district While the infections had been detected during a routine checkup between January and May 2025, the media attention came only earlier this week, after local media reports were released on the same.
This is not the first time this has happened. Similar case was seen from the eastern state of Jharkhand. This is where five children, all under the age of eight were also found to have contracted HIV after blood transfusions. All of them had thalassemia, and received blood transfusion at a state-run hospital.
Earlier, in 2011, Gujarat authorities launched an investigation after 23 children with thalassemia tested HIV positive following regular blood transfusions at a public hospital.
HIV or human immunodeficiency virus spreads to unprotected sex, unsafe medical practices, including infected blood transfusion, using used needles for tattooing, or from mother to child during pregnancy, childbirth, and breastfeeding. While the disease is not fatal, it does requires lifetime management. In India, more than 2.5 million people have HIV and 66,400 new infections have come up each year. As per the government data, 1.6 million people are on lifelong treatment at antiretroviral therapy (ART) centers.
Satna district collector Satish Kumar S said the five children had received blood transfusions at different centres, involving multiple donors, reported BBC. Health officials confirmed that the transfusions took place at both government hospitals and private clinics, and said all the children are currently undergoing treatment.
In one case, both parents of a three-year-old child were found to be HIV positive. In the remaining cases, the parents tested negative, ruling out mother-to-child transmission.
Satna’s chief medical and health officer, Manoj Shukla, said children who require repeated blood transfusions are treated as a high-risk group and are routinely screened for HIV. “Once the infection was detected, treatment was started immediately and is continuing. At present, the children are stable,” he said.
Dr Shukla added that every unit of blood issued by the district hospital’s blood bank is tested according to government protocols and released only after a negative report. However, he noted that in rare instances, donors in the very early stage of HIV infection may not be detected during initial screening but may test positive later.
Last week, thalassemia patients urged Parliament to pass the National Blood Transfusion Bill 2025, saying it would strengthen oversight of blood collection, testing and transfusion practices. Campaigners, including patients who contracted HIV through unsafe transfusions, described the proposed law as a long-overdue step towards ensuring safe and quality-assured blood for those who depend on frequent transfusions.
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