Headaches are a common symptom of a stressful lifestyle, your body not feeling well and other issues. While headaches can be dealt with easily, migraines are not so easy to handle. Migraines are a type of headache that feels like severe throbbing and pulsing sensation, almost like you are hearing your own heartbeat in your brain, usually on one side of the brain. Many people believe that migraines are not that big of a deal because you just have to deal with the pain, but that is not all migraine is, some people find it very difficult to do their daily tasks as they experience dizzying spells, nausea and extreme sensitivity to light and sound! These attacks can last hours and make it difficult for people to go about their daily lives as well. While there are medications available for migraine patients, these medications need time to take effect, so you may be in a lot of pain, but there are not many quick reliefs you can have in place other than learning the symptoms of a migraine attack and taking medication before it happens. But a new approval by the FDA may change this!

The U.S. Food and Drug Administration (FDA) has approved Symbravo, a new medicine to treat acute migraine attacks in adults. This means adults can now use Symbravo to get relief from their migraine symptoms. The FDA's decision was based on the results of three big studies, called Phase 3 trials. These trials involved over 21,000 migraine attacks, so the FDA has a lot of information about how well Symbravo works and how safe it is. The FDA only approves medicines that have been shown to be both safe and effective through a thorough testing process.

Importance of New Treatment Option

"Migraine attacks can happen suddenly and really mess up people's lives. It's estimated that over 39 million people in the U.S. alone get migraines," said Herriot Tabuteau, M.D., CEO of Axsome Therapeutics told US News. This shows how common migraines are and how important it is to have good treatments. "Symbravo gives patients and doctors a new option that can quickly stop a migraine attack, keep it away, and let people get back to their normal activities, all with just one dose." Having a medicine that can give fast and long-lasting relief from migraine pain is a big deal for millions of people. This new treatment is a real step forward in how we treat migraines.

Symbravo Trial Results, How Was It Approved

The trials took place in 3 steps, the Momentum trial study focused on people whose migraines had moderate to severe pain. The results showed that a lot more people taking Symbravo felt pain-free two hours after taking the medicine compared to those who took a placebo which is a dummy pill. Even better, many people felt relief for up to 24 and even 48 hours after just one dose. This long-lasting relief is really important for people with migraines because it means they can get back to their normal lives without worrying about the pain coming back. The study also looked at how many people were free from their worst symptom, like sensitivity to light or sound, or nausea. Symbravo worked better than the placebo in this area too.

While the intercept trial looked at people who took Symbravo when their migraine pain was still mild. Even when the pain was just starting, Symbravo was effective. The results were similar to the MOMENTUM trial, with many people getting pain relief and relief from their worst symptoms. Treating migraines early is often better because it can stop the pain from getting really bad.

And lastly the Movement trial which was to see how safe the medication is when people take it regularly. This study followed 706 people who had at least two migraines a month. The most common side effects people experienced were sleepiness and dizziness. While these side effects are important to know about, the study showed that Symbravo is generally safe for people to use on a regular basis.

The six-week-long incubation period of Hantavirus is a matter of concern, but the rat-borne disease is certainly not a large epidemic, said the World Health Organization today.

At a media briefing, the WHO Director General Dr Tedros Adhanom Ghebreyesus, expressed concerns about the time taken for the symptoms of the disease to appear.

He noted that so far the disease has been limited to the 150 people who traveled on board the MV Hondius ship. Of these, only 8 people have been infected - 3 have died, and 5 have been confirmed.

A case has been reported in a person who disembarked from the ship, without having the symptoms, and some have self-isolated to prevent the risk of spreading.

Among those on board the ship, now travelling to the Canary Islands, "currently no one is symptomatic".

However, "with a six-week incubation period, more cases are expected to be reported".

Countries involved in the contact tracing efforts of people who disembarked at St. Helena Islands include Canada, the Netherlands, Singapore, Turkey, the UK, and the US, the WHO chief said.

WHO infectious disease epidemiologist Maria Van Kerkhove reiterated that the disease spreads only among close, prolonged contacts or those providing care, as seen in the case of the doctor who got infected on board.

The WHO also noted that the disease is unlikely to become a large epidemic, as it's an isolated case occurring in a closed environment. However, public health measures like contact tracing and testing are key to preventing any further spread.

According to the WHO, the outbreak of the rat-borne disease among people aboard the MV Hondius ship after it left Argentina on April 1 was caused by the Andes strain.

Speaking to HealthandMe, Dr. Gautam Menon, Epidemiologist and Professor of Physics and Biology, Ashoka University, Delhi-NCR, said that the long incubation period is likely to complicate the spread of the hantavirus.

"What complicates matters is that incubation periods - the time between getting infected and symptoms showing - are large, up to several weeks, so passengers and their contacts will have to be quarantined for a long period before they can be declared safe." The expert said.

Is Hantavirus Similar To COVID-19?

Ven Kerkhove said that hantavirus causes severe respiratory issues, but it is still not the same as SARS-CoV-2.

This is not a new virus and is completely different from SARS-COV-2. It has caused similar outbreaks in Argentina in 2018, where contact tracing and other public health measures contained the spread.

"The outbreak of Hantavirus on a cruise ship has generated significant anxiety around the world, evoking memories of cruise ships affected by COVID-19 in the first phase of the pandemic. However, this is a different virus that is not known to spread efficiently from person to person. Its characteristics are already well-documented, unlike the SARS-CoV-2 virus, which was an unknown organism until then," Dr. Rajeev Jayadevan, Ex-President of IMA Cochin and Convener of the Research Cell, Kerala, told HealthandMe.

"The current cases do not indicate a pandemic threat, but they underline the growing importance of surveillance of zoonotic diseases. Strengthening rodent control, environmental hygiene, and early detection systems remains essential to prevent localized outbreaks and public panic. There is neither a proven treatment for its cure nor is there any vaccine," added Dr.Ishwar Gilada, Mumbai-based infectious disease expert.

How does The Hantavirus Affect The Human Body?

Hantavirus infection is caused by the hantavirus, which belongs to the Hantaviridae family. It is is rare but can be life-threatening.

The infection presents with initial symptoms resembling the flu and has a relatively high mortality of about 40%.

Even though this virus is not believed to spread very efficiently, it would have done so far more easily in the enclosed environment that the ship provided, the experts said.

Dr Neha Rastogi, Senior Consultant, Infectious Diseases, Fortis Memorial Research Institute, Gurugram, told HealthandMe that it can be contracted by coming into contact with rodent saliva, urine, and feces.

Hantavirus can cause infection - 2 syndromes: hantavirus pulmonary syndrome and haemorrhagic fever that may quickly develop into severe respiratory illness, as flu-like symptoms (fever, muscle aches, and fatigue) occur before developing serious respiratory symptoms (dyspnea) that may require respiratory assistance.

"On rare occasions, it can also spread from person to person through close contact. Rapid diagnosis and intensive medical treatment are critical for a successful outcome," Dr Rastogi said.

"Preventative measures include proper personal hygiene, avoiding contact with rodents or rodent-inhabited areas; using PPE when cleaning; and ensuring the area is well-ventilated," she added.

Although hantavirus infections can cause severe respiratory illness with high mortality, confirmed human cases globally remain relatively uncommon, Dr Gilada told HealthandMe

"The pneumonia syndrome caused by the virus is due to excessive permeability of blood vessels, resulting in fluid accumulation. It is managed with expert supportive care while the lungs recover, as there are currently no known antivirals or vaccines available for the Andes virus. By carefully tracking contacts and isolating those who might be infected, the virus can be stopped in its tracks, bringing this outbreak under control," Dr Jaydevan said.

Most people often wrap up their day at work with a sense of stress and severe exhaustion. But if you are part of the group that experiences severe headaches after office hours, it could be because of one common habit that may be causing you discomfort — chronic stress. When the mind keeps racing all day long because of deadlines, tension, and pressure, even during breaks, it leaves behind a sense of urgency. And that sense of urgency does not mitigate or come to an end when the day ends.

Why does stress build up even after work?

Several times, there are difficult or unpleasant situations at work — it could be because of unfinished tasks and conversations that play and replay in the mind. The nervous system, therefore, gets overburdened, thereby leading to headaches. According to doctors, a lot of corporate employees experience this pain after a day at their high-pressure jobs. And while it may sound like something that is out of your control, there is something that you can do.

How to deal with chronic stress after work?

Stress inherently is not bad for you, but only if it occurs in short bursts. In that case, it can improve performance, focus, and may even prepare the body to handle challenges. Problems, however, arise when stress becomes chronic. As a result, the nervous system starts to process both pain and stress at the same time, and while one is built to be highly adaptable, stress starts to respond to external and internal factors. When the brain continues to receive signals without getting ample time for recovery, the body enters a state of prolonged alertness.

In a sensitised state, situations that would otherwise be interpreted as minor may even get ignored. This can increase heart rate and muscle tension, thereby putting the nervous system into a fight-or-flight mode. In cases of constant headaches, sensitisation can lower the pain threshold. Consequently, headaches begin and become much harder to stop. Over time, this constant activation can disrupt the body's natural balance and create an environment for headaches to worsen.

Chronic stress and migraines

Chronic stress acts as a trigger for migraines — it can even worsen the discomfort. The neurological system of people experiencing migraines is more responsive to changes in hormones, environmental factors, and sleep patterns. Constant exposure to a stressor, therefore, can drive the severity and frequency of migraines. To make matters worse, muscle tension in the shoulders, neck, and scalp can also trigger headaches. Extended periods of sustained concentration and sitting can cause headaches later in the day.

Can sleep help reduce stress headaches?

Chronic stress has a debilitating impact on sleep quality as well. People who feel persistently wired at the end of the workday struggle to fall or stay asleep. As a result, the brain fails to recover properly. Poor sleep can therefore worsen the stress cycle, leading to headaches the next day as well. The loop is difficult to break, and excessive fatigue building up over time can make you feel overwhelmed. Over time, this loop leads to a decline in productivity, focus, and the ability to solve problems.

Public health officials in South Wales, UK, have issued an alert on a localized outbreak of hepatitis A, and have urged residents to maintain hygiene as well as vaccinate children.

Cases of hepatitis A involving the same strain have been identified in three separate households in Barry, according to Public Health Wales.

The health body, in a statement, said the strain’s characteristics “suggest the infection may be spreading locally.” Investigations into the “small number” of cases are ongoing.

To curb the outbreak, the officials have also issued an urgent appeal to parents to ensure their children remain “vigilant with their handwashing.”

Those infected are “receiving appropriate care and are recovering well,” Public Health Wales said. As a precaution, close contacts of the affected individuals have also been offered vaccination.

What Is Hepatitis A?

Hepatitis A is a viral liver infection caused by the hepatitis A virus (HAV). It spreads mainly through contaminated food or water, or through close personal contact with an infected person.

The infection can lead to liver inflammation, jaundice, extreme fatigue, and stomach pain. In most cases, it is a short-term illness that clears on its own without specific treatment, although severe cases can occur. Unlike hepatitis B or C, hepatitis A does not usually cause long-term liver damage.

According to the World Health Organization (WHO), vaccination remains the most effective way to prevent infection.

Also read: Hepatitis Infections Claims 1.3 Million Lives Worldwide, India Among Top Contributors: WHO

Symptoms of Hepatitis A

Symptoms usually appear a few weeks after exposure to the virus, although some people may not develop noticeable signs. According to the Cleveland Clinic, symptoms can include:

• Persistent fatigue and weakness
• Sudden nausea, vomiting, or diarrhea
• Pain or discomfort in the upper right side of the abdomen near the liver
• Pale or clay-colored stools
• Reduced appetite
• Mild fever
• Dark-colored urine
• Joint pain
• Yellowing of the skin and eyes (jaundice)
• Severe itching

Can Hepatitis A Be Prevented?

Read More: UK Parliament Bans Smoking For People Born After 2008: Know All About It

“The best way to prevent the spread of hepatitis A is to wash hands thoroughly with soap and water. This is important after using the toilet, changing nappies, and before preparing or eating food,” said Susan Mably, Consultant in Health Protection for Public Health Wales.

Vaccination against hepatitis A is also highly effective in preventing the disease.

Doctors recommend the vaccine for:

• Children older than 12 months
• Adults at risk of exposure at home or work
• Travelers visiting regions where the virus is more common
• People with existing liver conditions

• drinking boiled or bottled water,
• avoiding food from unhygienic sources,
• peeling fruits at home and not getting pre-cut from stores.

If someone in the household is infected, cleanliness becomes even more important. Surfaces should be disinfected, food prepared carefully, and personal items not shared.

Safe sexual practices also matter, as the virus can spread through oral-anal contact. On a broader level, preventing future outbreaks requires more than short-term fixes. Improving water quality, repairing sewage systems, and strengthening public health surveillance are essential to stop the cycle from repeating.