The US Food and Drug Administration has approved TNKase or Tenecteplase, which is a thrombolytic or clot-dissolving agent, for the treatment of acute ischemic stroke in adults.

Ischemic strokes happen when a blood clot blocks a blood vessel in your brain. It can cause permanent brain damage and death. If enough brain cells die, you can also lose the abilities or body functions those cells control. They are also the most common types of stroke, with 80% of all strokes being ischemic strokes.

How is TNKase administered?

It is delivered as a single five-second intravenous bolus, which is faster than the standard of care Activase or alteplase, which is administered as an intravenous bolus followed by a 60-minute infusion. The manufacturer of TNKase, Genetech said a new 25-mg vial configuration will also be available in the coming months.

How Was TNKase approved?

The approval came at the backdrop of a study that compared TNKase to Activase in patients with acute ischemic stroke. These patients also presented with a disabling neurological deficit. Results show that TNKase was comparable to Activase in terms of efficacy and safety.

How Common Are These Strokes?

In the United States it self, it affects more than 795,000 people each year and is the leading cause of long-term disability. It is also the fifth leading cause of death. Since brain damage can happen if this progresses rapidly, one needs an immediate, fast-acting medical care.

TNKase thus provide a faster and simpler administration which can be critical for anyone. The chief medical officer and head of global product development at Genetech, Levi Garraway, MD., PhD., said, "Today's approval is a significant step forward and underscores our commitment to advancing stroke treatment options for patients."

What Are The Symptoms Of Ischemic Strokes?

Some of the most common symptoms include weakness or paralysis on one side of your face and body. You may also feel trouble speaking or have loss of speech, also known as aphasia. You may faced slurred or garbled speaking, also known as dysarthria. Other symptoms include loss of muscle control on one side of your face, or sudden worsening or loss of your senses, including vision, hearing, smell, taste, and touch.

Other symptoms include:

• Loss of coordination or clumsiness
• Blurry vision or double vision
• Dizziness or vertigo
• Nausea and vomiting
• Neck stiffness
• Mood swings or sudden personality changes
• Confusion or agitation
• Seizures
• Memory loss (amnesia)
• Headaches which are sudden and severe
• Passing out or fainting
• Coma

Are There Any Warning Signs?

While these are symptoms one has who is prone to this condition. However, often, many may confuse it with other illnesses. It is best to keep an eye out for warning signs. These could be looking out for yourself or your loved one. Note if there is a sudden loss of balance. Look out for sudden vision loss or changes in one or both eyes. Look for a droop on one or both sides of your face, especially when you smile. Raise both arms and see if one arm sags or drops in a way it usually does not. Note for your speech. Are you as fluent? Are you have trouble speaking? If you see any of such signs, start tracking it and talk to your healthcare provider.

The FSSAI recently issued notices to three food business operators over what it described as misleading claims and labelling violations. The companies that have received notices are Heritage Foods Ltd for its paneer, Dia Foods for La Casa Vegan Hazelnut Chocolate Spread, and Cipzer Nutraceuticals for its juice capsules.

FSSAI Flags Down 3 Brands Over Misleading Claims

The food regulatory body directed the companies to provide explanations within seven days why action should not be initiated under the Food Safety and Standards Act, 2006.

The move is part of the regulator's broader ongoing crackdown on deceptive food packaging and marketing claims aimed at protecting consumers.

Also read: FSSAI Targets 6 Energy Drink Brands; Experts Link Them to Obesity, Liver Problems

Heritage Foods' Fresh Paneer Under FSSAI Scrutiny

FSSAI issued a notice to Heritage Foods, objecting to the use of the term “Fresh Paneer” on the packaging. It stated that the claim term does not meet the conditions laid down under Schedule V governing the use of the word “fresh”.

According to the regulator, the label “Fresh Paneer” is liable to mislead consumers because it does not satisfy the prescribed criteria for using the term.

La Casa Vegan Chocolate Spread Accused Of Misleading Claims

FSSAI also issued a notice to Dia Foods over its La Casa Vegan Hazelnut Chocolate Spread, alleging that several claims displayed on the packaging could mislead consumers. Among the claims questioned are:

• "All Natural"

• "100% Organic"

• "Vegan"

The regulator further pointed out that the product uses the phrase "100% Organic & Vegan”, which could be misleading as it has not obtained approvals like organic and vegan food.

Further, according to FSSAI, the packaging does not display the mandatory organic certification marks, including the Jaivik Bharat logo required under Indian regulations.

It also objected to its use of “100%” as the food regulatory body has stated that it cannot be defined under FSS Act, 2006.

Also read: Popular Biscuit Brand Under FSSAI Scrutiny For Misleading ‘100% Atta’ & ‘No Added Sugar’ Claims

Cipzer Nutraceutical Also Got Served

A third notice was issued to Cipzer Nutraceuticals over its juice capsules. FSSAI said the product carries claims that violate food labelling and advertising regulations.

In its notice, it said that the product carried the claim “FSSAI-approved” which could imply that FSSAI specifically endorsed it.

Other reasons listed in the complaint stated that the product boasted of claims like “Boost your immune system” and “remove toxins from your body”, which had no scientific backing. It also said the product’s packaging depicted pictures of various vegetables that were listed in the ingredient list.

The regulatory body added that the product also claimed the presence of Vitamin C and Vitamin E but failed to substantiate it scientifically.

The makers also claimed that the capsules are “made from organic vegetables”. FSSAI said that it could mislead the consumers as it does not carry the prescribed organic certification, including Jaivik Bharat Logo.

FSSAI’s Recent Crackdowns

The latest notices are part of FSSAI's ongoing crackdowns against misleading food claims. In recent weeks, the regulator has issued notices to several food companies over the use of terms like “100%,” “healthy,” “organic,” “natural,” and “fresh” as they do not comply with food labelling and advertising regulations.

The regulator has maintained that such claims can influence consumer purchasing decisions and must be scientifically substantiated and legally compliant.

Prominent brands that faced FSSAI scrutiny includes Red Bull Energy Drink, PepsiCo – Adrenaline Rush Energy Drink, Reliance Consumer Products – Campa Energy Gold Boost, Sting Energy Drink, Hell Energy, Coca-Cola-backed Monster, Eat Fit Digestive Biscuits, Emami (Healthy & Tasty), Health Aid, Troovy, The Healthy Factory, Healthy Master, Healthy Choice, Plan B Foods, and Neuherbs.

Violation Of Food Safety In India

Also read: FSSAI Tightens Food Safety Norms, Mandates Food-Grade Knives, Cutting Tools

HealthandMe had reported food contamination from Indore's Bhagirathpura, the same place that was the epicenter of water contamination that claimed many lives. HealthandMe also reported the news of Horlicks adulteration in Odisha.

In another news, bacteria were found in Amul milk packages, along with Mother Dairy and Country Delight. Eggoz, too, landed in a controversy, when a YouTube video went viral claiming that the sample tested positive for Nitrofuran.

MicrobioTx, a Bengaluru-based gut health startup, tested samples from urban populations across 9 Indian states and 14 cities and found that people are significantly exposed to pesticides, insecticides, antibiotics, steroidal growth regulators, and forever chemicals.

The independent study reported the following findings:

• 78% were exposed to pesticide residues, with 36% exposed to three or more pesticides, indicating cumulative exposure that may pose serious health risks.

• 54% showed presence of antibiotics, linked to antimicrobial resistance, harder-to-treat infections, and disruption of the gut microbiome that may contribute to metabolic disorders.

• 39% were exposed to steroids, compounds that may cause endocrine disruption, and increased carcinogenic risk.

• 38% tested positive for forever chemicals, persistent toxins that may cause cancer risk, reduced fertility, thyroid disease, hormone suppression, high cholesterol, liver damage, and ulcerative colitis.

• 17% of the samples had 10 or more toxins in their blood across 3 categories, indicating hidden chronic exposure.

The cyclospora parasite outbreak in the US is continuing to grow, with cases nearing 900, according to local health officials.

While infections have been reported in about 18 states, Michigan and Ohio continue to see the highest number of cases of the intestinal infection.

As of July 6, 678 cases of cyclosporiasis had been confirmed, an official from the Michigan Department of Health and Human Services (MDHHS) told ABC News. This is an increase from roughly 300 cases reported last week. The state annually records up to 50 cases, but the current outbreak is about 13.5 times higher than average.

According to Dr. Natasha Bagdasarian, an infectious disease physician, epidemiologist, and the chief medical executive for the state of Michigan, the figure is a "moving target," meaning cases are likely to continue rising.

"There is a significant lag time between exposure to contaminated produce or contaminated materials and development of symptoms," she told ABC News. "So it can take a week, sometimes even two weeks between exposure and development of symptoms."

In Ohio, there were 177 cases of cyclosporiasis as of July 2, Ken Gordon, press secretary for the Ohio Department of Health's communications office, was quoted as saying.

Cases have been confirmed across 43 counties in Ohio so far this year, according to Gordon. Nearly 171 cases have been reported since June 20.

Meanwhile, the Centers for Disease Control and Prevention (CDC) reported that 145 cases had been detected in 17 states since May 1, excluding Michigan, as of June 16, with at least 20 people hospitalized. No deaths have been reported.

The CDC said cases ranged in age from 5 to 86 years, with a median age of 42. About 61 per cent of patients were female.

So far, no cases have been linked between states, and health officials are still investigating whether there is a common source of the outbreak in Michigan.

Also read: Cyclospora Parasite Spreads to More US States: Foods to Avoid Right Now

How to Prevent Cyclospora Infection

The CDC recommends following safe food handling practices to reduce the risk of infection:

• Wash your hands with soap and water before and after handling fresh fruits and vegetables.
• Wash all fruits and vegetables thoroughly under running water before eating, cutting, or cooking.
• Produce labeled "prewashed" does not need to be washed again.
• Scrub firm produce, such as melons and cucumbers, with a clean produce brush.
• Cut away any bruised or damaged areas before eating.
• Refrigerate cut, peeled, or cooked fruits and vegetables within two hours.

The parasite spreads through food or water contaminated with human feces and is not spread directly from person to person.

According to Dr. Darien Sutton, an emergency medicine physician, proper handwashing is very important.

"This type of parasite doesn't easily go away with alcohol-based hand sanitizer. So, good old handwashing is really key here," said the ABC News medical correspondent.

What Is Cyclospora cayetanensis?

Read More: Bryan Johnson Blames Sugary Cereals, Soda and Stress for His Autoimmune Disease; Shares Treatment Plan

Cyclospora cayetanensis is a parasite that causes cyclosporiasis, a form of food poisoning.

People can become infected through contaminated food or water. The infection causes watery diarrhea and other intestinal symptoms.

A Cyclospora infection can be mild or severe and may last for weeks or even months. It is typically treated with antibiotics.

People with weakened immune systems, such as those with HIV/AIDS or cancer, are at greater risk of severe disease.

Symptoms of Cyclospora Infection

Symptoms of cyclosporiasis usually begin within a week of exposure to contaminated food or water and include:

• Watery or explosive diarrhea
• Loss of appetite
• Bloating and gas
• Fatigue (extreme tiredness)
• Low-grade fever
• Nausea
• Stomach cramps
• Vomiting.

The launch of the weight-loss drug Wegovy has sparked fresh concerns among pharmacists in the UK, who warn that the new tablet format could make it easier for manufacturers to produce and sell counterfeit medicines.

Wegovy Demand Sparks Counterfeit Concern

The once-daily semaglutide pill, developed by Novo Nordisk, recently became available through private high street and online pharmacies after receiving approval from the UK's Medicines and Healthcare products Regulatory Agency (MHRA).

While the pill is expected to help patients who are reluctant to use injections, experts fear it may also increase the risk of a growing black market for fake weight-loss drugs.

According to a survey conducted by the National Pharmacy Association (NPA) with 310 pharmacies, 97% believe that the weight loss tablet could lead to an increase in counterfeit products being sold unlawfully.

Olivier Picard, chairman of the National Pharmacy Association said, “As this survey shows, pharmacies are concerned about a dangerous and growing black market for weight loss medicines, with tablet form of medication likely to be easier for criminals to counterfeit.”

He said that all patients must visit an authorised pharmacy for Wegovy pills.

He added: “Patients should only ever obtain weight loss medication from a regulated pharmacy after an appropriate consultation with a healthcare professional. Fake medicines pose a serious risk to health because they may contain harmful ingredients or incorrect doses.”

Also read: Wegovy Weight Loss Pill Available in UK Pharmacies From Today: All You Should Know

Global Concern

Unlike injectable medications of GLP-1, tablets often require less sophisticated manufacturing equipment, which makes it easier to make counterfeits.

As the medicated weight loss market is rising after the popularity of GLP-1 medications increased, criminals can produce fake pills on a large scale, using simple equipment.

Counterfeit GLP-1 medicines have already become a growing global concern. In September 2025, the European Medicines Agency (EMA) said that there had been a sharp rise in illegal forms of semaglutide and other GLP-1 medicines online.

The agency also warned that these fake medicines may contain no active ingredient, improper doses, or harmful substances that can lead to failure of treatment or serious health complications.

Demand for GLP-1 medicines such as Wegovy and Mounjaro has soared worldwide as studies continue to demonstrate significant weight loss benefits.

Also read: Can Ozempic-Like GLP-1 Drugs Slow Aging, Boost Longevity?

Clinical trials of the oral Wegovy tablet have shown participants taking the highest dose lost approximately 14% to 17% of their body weight over 64 weeks when combined with diet and exercise. However, pharmacists say the popularity of these treatments has also created opportunities for fraudsters.

Experts urge consumers to avoid purchasing weight-loss medicines from unofficial online sellers or social media advertisements, regardless of how attractive the prices appear.

Genuine GLP-1 medicines require a medical consultation and prescription, and authorised pharmacies carry out necessary clinical checks before selling them.

About Wegovy

The semaglutide (Wegovy) tablet is the first oral glucagon-like peptide-1 (GLP-1) medicine approved in the UK for weight loss.

It can be prescribed alongside a reduced-calorie diet and increased physical activity for adults who have obesity (BMI of 30 or above), or are overweight (BMI between 27 and 30), and have at least one weight-related comorbidity