The US Food and Drug Administration has approved TNKase or Tenecteplase, which is a thrombolytic or clot-dissolving agent, for the treatment of acute ischemic stroke in adults.

Ischemic strokes happen when a blood clot blocks a blood vessel in your brain. It can cause permanent brain damage and death. If enough brain cells die, you can also lose the abilities or body functions those cells control. They are also the most common types of stroke, with 80% of all strokes being ischemic strokes.

How is TNKase administered?

It is delivered as a single five-second intravenous bolus, which is faster than the standard of care Activase or alteplase, which is administered as an intravenous bolus followed by a 60-minute infusion. The manufacturer of TNKase, Genetech said a new 25-mg vial configuration will also be available in the coming months.

How Was TNKase approved?

The approval came at the backdrop of a study that compared TNKase to Activase in patients with acute ischemic stroke. These patients also presented with a disabling neurological deficit. Results show that TNKase was comparable to Activase in terms of efficacy and safety.

How Common Are These Strokes?

In the United States it self, it affects more than 795,000 people each year and is the leading cause of long-term disability. It is also the fifth leading cause of death. Since brain damage can happen if this progresses rapidly, one needs an immediate, fast-acting medical care.

TNKase thus provide a faster and simpler administration which can be critical for anyone. The chief medical officer and head of global product development at Genetech, Levi Garraway, MD., PhD., said, "Today's approval is a significant step forward and underscores our commitment to advancing stroke treatment options for patients."

What Are The Symptoms Of Ischemic Strokes?

Some of the most common symptoms include weakness or paralysis on one side of your face and body. You may also feel trouble speaking or have loss of speech, also known as aphasia. You may faced slurred or garbled speaking, also known as dysarthria. Other symptoms include loss of muscle control on one side of your face, or sudden worsening or loss of your senses, including vision, hearing, smell, taste, and touch.

Other symptoms include:

• Loss of coordination or clumsiness
• Blurry vision or double vision
• Dizziness or vertigo
• Nausea and vomiting
• Neck stiffness
• Mood swings or sudden personality changes
• Confusion or agitation
• Seizures
• Memory loss (amnesia)
• Headaches which are sudden and severe
• Passing out or fainting
• Coma

Are There Any Warning Signs?

While these are symptoms one has who is prone to this condition. However, often, many may confuse it with other illnesses. It is best to keep an eye out for warning signs. These could be looking out for yourself or your loved one. Note if there is a sudden loss of balance. Look out for sudden vision loss or changes in one or both eyes. Look for a droop on one or both sides of your face, especially when you smile. Raise both arms and see if one arm sags or drops in a way it usually does not. Note for your speech. Are you as fluent? Are you have trouble speaking? If you see any of such signs, start tracking it and talk to your healthcare provider.

The Democratic Republic of the Congo’s (DRC) Ebola outbreak has become the second-largest Ebola epidemic ever recorded, overtaking the country’s devastating 2018-2020 outbreak.

The current epidemic has also underscored the growing global concern over the rapid spread of the deadly disease.

Second-Largest Ebola Outbreak In DR Congo

According to the latest official figures released by the DRC health authorities and the European Centre for Disease Prevention and Control (ECDC), the country has reported 3,442 confirmed Ebola cases and 1,521 deaths as of July 29, 2026.

However, more recent updates indicate the outbreak has continued to worsen rapidly, with 3,532 confirmed cases and 1,556 deaths reported by July 31, 2026.

The only Ebola outbreak larger than the current epidemic remains the 2014-2016 West Africa outbreak, which infected more than 28,000 people and resulted in the deaths of over 11,300 lives.

Also read: Milestone In Kala-Azar Treatment: WHO Updates Treatment Guidelines, Recommends Shorter & Safer Regimens

Ebola Outbreak Caused By Rare Bundibugyo Virus

Unlike many previous Ebola outbreaks caused by the Zaire ebolavirus, the ongoing epidemic is caused by the Bundibugyo virus, a rarer species of Ebola virus for which there is currently no approved vaccine or licensed treatment.

The World Health Organization (WHO) said the outbreak remains active with heightened community transmission, particularly in eastern DRC, where insecurity, mistrust, population displacement and limited healthcare access continue to hamper outbreak containment efforts.

WHO Warns

In its latest Disease Outbreak News update, WHO said, “The outbreak remains active, with sustained transmission.”

The UN health agency noted that inside conflict, population displacement, community mistrust and restricted access to affected areas continue to affect contact tracing, surveillance, and containment and treatment activities.

WHO has also stressed that although the global risk remains low, the regional risk is high because of frequent cross-border movement between the DRC and neighbouring countries.

A major challenge in controlling the epidemic is the absence of a licensed vaccine or targeted therapy against the Bundibugyo virus.

According to WHO, while the Ebola vaccine used against the Zaire strain has shown limited experimental cross-protection in animal studies, there is currently inadequate evidence to recommend its use against Bundibugyo virus disease.

Also read: Uganda Declared Ebola-Free As Congo Outbreak Grows To 3,262 Cases, 1,437 Deaths

First Volunteer Receives Experimental Bundibugyo Vaccine

Amid the worsening outbreak, researchers have reached an important milestone in Ebola vaccine development.

The first volunteer has received an experimental vaccine targeting the Bundibugyo strain of Ebola, marking the world's first Phase I clinical trial for this virus, according to the University of Oxford.

The vaccine, ChAdOx1 BDBV, developed in collaboration with Serum Institute of India (SII), is designed specifically to protect against the Bundibugyo strain of Ebola.

It uses the same viral vector platform that powered the Oxford-AstraZeneca COVID-19 vaccine.

The vaccine uses a genetically modified chimpanzee adenovirus (ChAdOx1)—a harmless virus that normally causes the common cold in chimpanzees—as a delivery vehicle.

"We welcome the start of the phase 1 clinical trial of an investigational vaccine against Ebola Bundibugyo virus disease—an important step to assess the safety and immune responses generated by the vaccine," said WHO Director-General Tedros Adhanom Ghebreyesus on X.

Health authorities, supported by WHO, Africa CDC and international partners, continue to strengthen surveillance, laboratory testing, infection prevention, community engagement and patient care.

The growing popularity of GLP-1 weight loss drugs like Ozempic, Wegovy and Mounjaro has brought another side effect into focus.

After the widely discussed 'Ozempic Face,' dermatologists are now warning about 'Ozempic Hair,' a term used to describe excessive hair shedding that can occur after rapid and weight loss.

Experts say the condition is not caused by the medication directly damaging hair follicles. Instead, it is largely linked to rapid weight loss, nutritional deficiencies, and the body's metabolic response to sudden calorie restriction.

Why Are GLP-1 Users Facing Excessive Hair Loss?

According to Dr. Gaurav Garg, Senior Dermatologist, Hair Transplant Surgeon, Dermato-Surgeon and Medical Director at Dermalife Skin and Hair Clinic, New Delhi, cases have become increasingly common in dermatology clinics.

"We are seeing a significant rise in patients complaining of excessive hair shedding after taking GLP-1 weight loss medications. Around 40% of the weight loss drug users visiting our clinics are experiencing mild to significant hair loss, with many noticing hair falling out in large clumps while washing or combing. In most cases, the medication itself is not directly damaging the hair. The problem is rapid weight loss, nutritional deficiencies and the metabolic shock experienced by the body," Dr. Garg said.

He added that the increasing use of these medications without proper medical supervision is further contributing to the problem.

"Ozempic isn't the enemy of your hair; malnutrition and metabolic shock are. By ensuring gradual weight loss and proper nutritional support under expert guidance, many of these problems can be prevented," he said.

Also read: UK Woman Spends £4,000 On Wegovy, Mounjaro, But Loses Less Than 14 Pounds In 15 Months

What Is 'Ozempic Hair'?

'Ozempic Hair' is not a medical diagnosis but a popular term for telogen effluvium, a temporary phase of hair loss due to stress. Rapid weight loss acts as a physical stressor, causing a larger number of hair follicles to enter the resting phase prematurely.

Hair shedding usually becomes noticeable three to four months after a user starts taking GLP-1 drugs. Reduced appetite during treatment may also result in deficiencies of all the nutrients that are important for hair growth. For example, protein, iron, zinc and biotin.

Also read: GLP-1 Microdosing: People Are Experimenting With Weight Loss Drugs & What Do Experts Have To Say About It?

Experts Warn Against Self-Medication

Dr. Garg cautioned that weight loss injections are increasingly being used for cosmetic purposes rather than for legitimate medical conditions.

"One of the biggest concerns today is that these weight loss injections are increasingly being viewed as quick-fix cosmetic solutions rather than prescription medicines meant for specific medical conditions. Many people begin taking them after watching social media content or on the advice of friends, without understanding the nutritional consequences. Hair shedding in most cases is temporary, but prevention is always better than treatment. These medications should never be used casually or without expert supervision," he said.

He stressed that people undergoing medical weight loss should receive appropriate dietary counselling, consume adequate protein, and undergo regular monitoring to reduce nutritional complications.

Echoing these concerns, Dr. Ramanjeet Singh, Director, Department of Dermatology, Medanta Hospital, said the trend reflects the risks of unsupervised use of GLP-1 medications.

"The emerging trend of 'Ozempic Hair' highlights the risks associated not only with rapid weight loss but also with the indiscriminate use of these medications without proper medical evaluation. We are increasingly seeing individuals obtaining weight loss drugs without specialist consultation or using them beyond recommended doses in pursuit of faster results. Hair shedding in such cases usually represents telogen effluvium triggered by rapid metabolic changes and nutritional deficiencies rather than permanent damage to the hair follicles," Dr. Singh said.

He added that the condition is generally reversible with timely intervention, balanced nutrition and medically supervised weight management.

Dermatologists advise people considering prescription weight loss medications to undergo a medical evaluation before starting treatment.

Maintaining adequate protein intake, avoiding crash diets, correcting iron and vitamin deficiencies where necessary, and seeking early dermatological care if excessive hair shedding develops may help reduce the severity and duration of hair loss.

On Sunday, Prime Minister Narendra Modi launched the 'Nasha Mukt Yuva for Viksit Bharat Sankalp Abhiyan'.

It is a nationwide 100-week campaign aimed at discouraging young people from substance abuse through community participation, awareness activities and various other initiatives.

About Nasha Mukt Yuva for Viksit Bharat Sankalp Abhiyan

Launched via video conferencing, the campaign seeks to transform young Indians into ambassadors of a drug-free society. The campaign has weekly events scheduled every Sunday across the country.

More than 10,000 locations joined the launch virtually, bringing together MY Bharat volunteers, National Service Scheme (NSS) members, schools, colleges, universities, NGOs, industry associations and over 125 spiritual organisations.

Addressing the gathering, Prime Minister Modi said that a healthy and drug-free youth population is essential for building a developed India (Viksit Bharat).

The Prime Minister said, "A drug-free youth is the greatest strength of Viksit Bharat. This campaign should reach every village, every town and every city through Jan Bhagidari."

He also said that substance abuse not only destroys individual lives and families but can also become a tool used by hostile enemy forces to weaken the country's future.

He also said, "Drugs destroy families, careers and the future of young people. Parents, teachers and society must come together to protect our youth from this menace." A healthy youth is the greatest strength of a Viksit Bharat. If our young generation stays fit physically and mentally, no force can stop India's progress."

Also read: Healthcare In India No Longer A Privilege, Becoming A Right: PM Modi

What Will Happen Over The Next 100 Weeks?

Unlike one-day awareness campaigns, the initiative is designed as a long-term public movement. Every Sunday, communities across India will organise activities such as:

• Walkathons and cycling events
• Sports competitions
• Meditation and yoga sessions
• Nukkad nataks and cultural programmes
• Art and poster competitions
• Community discussions and awareness drives

The government hopes the sustained weekly engagement will encourage behavioural change, especially among adolescents and young adults, while strengthening grassroots participation.

Also read: PM Modi Pledges 7.5 million For Cancer Moonshot Initiative: What Is It

A Broad Anti-Drug Strategy

The campaign builds on a series of youth-focused initiatives launched this year under the 'Nasha Mukt Yuva for Viksit Bharat' umbrella, including the National Nasha Mukti Quiz, awareness programmes in educational institutions, the Nasha Mukti Anthem initiative and youth conclaves across the country.

These efforts are part of the broader Nasha Mukt Bharat Abhiyaan, which has been expanded nationwide to curb drug problem through prevention, awareness and community engagement.

Officials say the latest campaign aims to create a society-level movement by bringing together educational institutions, youth organisations, society groups, corporate bodies and spiritual organisations on a common platform.

With one crore youth also taking the Nasha Mukti pledge during the launch, the government hopes the campaign will evolve into one of India's largest community-led efforts to prevent substance abuse.