The US Food and Drug Administration has approved TNKase or Tenecteplase, which is a thrombolytic or clot-dissolving agent, for the treatment of acute ischemic stroke in adults.

Ischemic strokes happen when a blood clot blocks a blood vessel in your brain. It can cause permanent brain damage and death. If enough brain cells die, you can also lose the abilities or body functions those cells control. They are also the most common types of stroke, with 80% of all strokes being ischemic strokes.

How is TNKase administered?

It is delivered as a single five-second intravenous bolus, which is faster than the standard of care Activase or alteplase, which is administered as an intravenous bolus followed by a 60-minute infusion. The manufacturer of TNKase, Genetech said a new 25-mg vial configuration will also be available in the coming months.

How Was TNKase approved?

The approval came at the backdrop of a study that compared TNKase to Activase in patients with acute ischemic stroke. These patients also presented with a disabling neurological deficit. Results show that TNKase was comparable to Activase in terms of efficacy and safety.

How Common Are These Strokes?

In the United States it self, it affects more than 795,000 people each year and is the leading cause of long-term disability. It is also the fifth leading cause of death. Since brain damage can happen if this progresses rapidly, one needs an immediate, fast-acting medical care.

TNKase thus provide a faster and simpler administration which can be critical for anyone. The chief medical officer and head of global product development at Genetech, Levi Garraway, MD., PhD., said, "Today's approval is a significant step forward and underscores our commitment to advancing stroke treatment options for patients."

What Are The Symptoms Of Ischemic Strokes?

Some of the most common symptoms include weakness or paralysis on one side of your face and body. You may also feel trouble speaking or have loss of speech, also known as aphasia. You may faced slurred or garbled speaking, also known as dysarthria. Other symptoms include loss of muscle control on one side of your face, or sudden worsening or loss of your senses, including vision, hearing, smell, taste, and touch.

Other symptoms include:

• Loss of coordination or clumsiness
• Blurry vision or double vision
• Dizziness or vertigo
• Nausea and vomiting
• Neck stiffness
• Mood swings or sudden personality changes
• Confusion or agitation
• Seizures
• Memory loss (amnesia)
• Headaches which are sudden and severe
• Passing out or fainting
• Coma

Are There Any Warning Signs?

While these are symptoms one has who is prone to this condition. However, often, many may confuse it with other illnesses. It is best to keep an eye out for warning signs. These could be looking out for yourself or your loved one. Note if there is a sudden loss of balance. Look out for sudden vision loss or changes in one or both eyes. Look for a droop on one or both sides of your face, especially when you smile. Raise both arms and see if one arm sags or drops in a way it usually does not. Note for your speech. Are you as fluent? Are you have trouble speaking? If you see any of such signs, start tracking it and talk to your healthcare provider.

Sri Lanka is facing a meningitis outbreak, and according to the Health Promotion Bureau of Sri Lanka, 200 people have been infected by this virus. As of now, about 50 people are getting treatment at the hospitals across four districts.

The disease was first found among a group of school goers in the Deniyaya area before spreading to other areas, including Diyatalawa, Welimada, and Rikillagaskada. The health authorities of the island nation have already issued special guidelines to stop the spread of the disease.

The authorities there said the disease mainly spreads through contaminated food and water, and it can also be transmitted through droplets released when an infected person coughs or sneezes, as well as through close contact. The citizens were also asked to drink boiled water and avoid crowded places.

The Health Ministry of Sri Lanka has appointed a special team consisting of virologists and epidemiologists to conduct observations on the viral meningitis condition reported from the Central and Southern provinces and to identify its viral transmission pattern.

“Though the cases show signs of meningitis, they have rarely progressed to encephalitis, a potentially life‑threatening inflammation of brain tissue, as the virus itself is self-limiting, allowing the immune system to overcome the ailment,” the deputy minister, Dr. Wijeyamuni, said.

What Is Meningitis?

Meningitis is an infection of the protective membranes around the spinal cord and the brain. It can become very serious if not treated or diagnosed in time. It is a consequence of bacterial or viral infection. Despite being a rare occurrence, the infection can spread through coughs, sneezes, a cold, or physical contact in the form of kissing.

Understanding the symptoms, causes, and treatment options is important for early diagnosis and timely medical care.

Also Read: Does Meningitis Always Cause Fever?

Symptoms Of Meningitis

Health officials urged the public to remain alert to the warning signs of meningococcal meningitis. Common symptoms include:

• Rash
• Headache
• Neck stiffness
• Fever
• Drowsiness
• Nausea or vomiting
• Increased sensitivity to light

How is Meningitis Diagnosed?

Physicians diagnose meningitis using a combination of clinical presentation, laboratory examinations, and imaging tests. Important diagnostic tests are Lumbar Puncture (Spinal Tap), Blood Cultures, and Imaging (CT or MRI Scans).

US President Donald Trump has declared himself to be in good health after undertaking the third annual medical check-up in his second term as the oldest American President.

Trump, who turns 80 next month, saw his doctors at the Walter Reed National Military Medical Center for a routine health check up on May 26.

“Everything checked out PERFECTLY,” Trump wrote on social media. He has, however, offered no details about what doctors observed.

The White House hasn't so far released details from Trump’s health check up to support his claim, or clarify what tests the president had undergone as part of the clinical exam.

As per an earlier statement from the White House, the visit involved “routine annual dental and medical assessments as part of his regular preventive health care,” but did not offer additional details on the medical exam.

His previous annual check-up was in April 2025. In October, he underwent another check-up.

“You have five doctors sitting there and … the questions are very easy at the beginning, then pretty easy, then pretty hard by the time you get to the end, there are not a lot of people in the room who can get them, believe me,” Trump informed the crowd at a rally in New York state last week about the impending test, The Times reported.

“So the first question was, you have a bear, a snake, an elephant, and a horse. Name the horse. That’s the horse. The second question is a little tougher,” he said.

“Toward the end, they had a question like, pick a number, sir, any number. OK. 203. Multiply times nine, divided by two, add 1324, subtract 1292. Sir, multiply it out one more time by 19. What is the answer, sir? I got it right … and the one doctor said, I’ve been doing this test for 20 years, I’ve never seen anybody ace it. … So I’ve taken it, and I’ve aced it all three times, I’ll tell you, because it is a positive thing.”

Trump In ‘Excellent Health’

Also read: ‘Sea Or See?’ Donald Trump's Remark Sparks Fresh Cognitive Health Speculation

The president’s health has been the subject of intense scrutiny — ranging from his mental state to visible bruising around his hands.

Trump — who has frequently criticized former President Joe Biden over age-related health and fitness issues — has recently remarked on how good he feels despite his age.

Trump said he feels the same as he did 50 years ago. “I feel literally the same,” he said at an Oval Office event. “I don’t know why. It’s not because I eat the best foods,” AP reported.

Read More: Russia's New Ebola Vaccine To Protect Against Rare Bundibugyo Strain, Says Health Minister

He also joked about his exercise regimen, saying that he works out “like about one minute a day, max.”

According to a White House summary of his previous annual medical examination in April last year, Trump was found to be in “excellent cognitive and physical health”.

“A comprehensive neurological examination revealed no abnormalities in his mental status, cranial nerves, motor and sensory functions, reflexes, gait, and balance. Cognitive function, assessed using the Montreal Cognitive Assessment (MoCA), was normal with a score of 30 out of 30,” his White House physician, Captain Sean Barbabella, wrote.

There were tests for depression and anxiety, and Trump recorded a score “within the normal range for both,” although numbers were not given.

Scans in October also demonstrated that Trump is in “excellent overall health”.

Amid the rising heatwave conditions in India, Prime Minister Narendra Modi today expressed his concerns and advised the citizens to stay hydrated.

In a post shared on the social media platform X, PM Modi asked people to take precautions as well as help fellow citizens by offering drinking water.

"Temperatures are continuously rising in different parts of the country, and along with this, the many difficulties caused by the heat in daily life are also increasing. I urge all my fellow citizens to take as many precautions as possible. Please keep yourselves hydrated and carry water with you when stepping out of your homes,” the Prime Minister said.

“In such weather, your sensitivity also becomes a great source of support. If possible, do offer a glass of water to anyone who is thirsty. I also appreciate those people who keep water in pitchers outside their homes and shops so that anyone can drink from them,” he added.

Temperatures Are Rising Throughout The Nation

The post comes as the temperature is increasing throughout the country.

According to the Indian Meteorological Department (IMD), the maximum temperature is expected to reach around 45°C on Wednesday, while the minimum may stay close to 28°C.

This extreme heat has become a serious public health challenge, as it affects everything from hydration levels in the body to digestion, the health of your skin, heart, and even mental well-being.

The department has issued a clear warning for a “heatwave.” Strong surface winds are also expected during the afternoon and evening. Humidity levels on May 27 are forecast to vary between 40 per cent at the highest and 25 per cent at the lowest.

Authorities have cautioned that the heatwave may be accompanied by strong, hot winds later in the day. People are advised to stay indoors during peak afternoon hours, remain hydrated, and take necessary measures to avoid direct exposure to sunlight.

Speaking to HealthandMe, Dr. L.K Jha, Associate Director & Head Unit-II– Cardiology, Asian Hospital, Faridabad, said how extreme heat levels can increase heart conditions such as palpitations.

“Dehydration contributes to palpitations associated with heatwaves significantly due to excessive sweating, fluid loss, and critical electrolyte loss, which all play key roles in maintaining normal heart rhythm and health of the cardiovascular system. Dehydration causes decreases in blood pressure, forcing the heart to increase its rate during periods of heat exposure if an individual is dehydrated”.

Read Also: Heatwave Hacks: A Complete Survival Plan for Extreme Indian Summer

How To Stay Fit During a Heat Wave?

• Drink water consistently at regular intervals instead of gulping large quantities at once. Electrolyte-rich fluids like coconut water, lemon water with a pinch of salt, or buttermilk are healthy, affordable options to soothe parched throats.

• Add items like curd, rice, cucumber, and bottle gourd to your diet and avoid red meat and fried foods during peak summer days.

• Extreme temperatures put additional stress on the cardiovascular system, especially in people with hypertension, diabetes, or heart conditions. Make sure to take all prescribed medications exactly as advised—don’t skip doses even if you experience heat-induced nausea. If you feel dizzy or experience palpitations or severe fatigue, consult your doctor as soon as possible.

• Air conditioning is helpful, but overexposure can lead to dry skin, headaches, and respiratory discomfort. Once every two or three hours, step away from your desk for a few minutes. Walk or stand, and sip some water.