The US Food and Drug Administration has approved TNKase or Tenecteplase, which is a thrombolytic or clot-dissolving agent, for the treatment of acute ischemic stroke in adults.

Ischemic strokes happen when a blood clot blocks a blood vessel in your brain. It can cause permanent brain damage and death. If enough brain cells die, you can also lose the abilities or body functions those cells control. They are also the most common types of stroke, with 80% of all strokes being ischemic strokes.

How is TNKase administered?

It is delivered as a single five-second intravenous bolus, which is faster than the standard of care Activase or alteplase, which is administered as an intravenous bolus followed by a 60-minute infusion. The manufacturer of TNKase, Genetech said a new 25-mg vial configuration will also be available in the coming months.

How Was TNKase approved?

The approval came at the backdrop of a study that compared TNKase to Activase in patients with acute ischemic stroke. These patients also presented with a disabling neurological deficit. Results show that TNKase was comparable to Activase in terms of efficacy and safety.

How Common Are These Strokes?

In the United States it self, it affects more than 795,000 people each year and is the leading cause of long-term disability. It is also the fifth leading cause of death. Since brain damage can happen if this progresses rapidly, one needs an immediate, fast-acting medical care.

TNKase thus provide a faster and simpler administration which can be critical for anyone. The chief medical officer and head of global product development at Genetech, Levi Garraway, MD., PhD., said, "Today's approval is a significant step forward and underscores our commitment to advancing stroke treatment options for patients."

What Are The Symptoms Of Ischemic Strokes?

Some of the most common symptoms include weakness or paralysis on one side of your face and body. You may also feel trouble speaking or have loss of speech, also known as aphasia. You may faced slurred or garbled speaking, also known as dysarthria. Other symptoms include loss of muscle control on one side of your face, or sudden worsening or loss of your senses, including vision, hearing, smell, taste, and touch.

Other symptoms include:

• Loss of coordination or clumsiness
• Blurry vision or double vision
• Dizziness or vertigo
• Nausea and vomiting
• Neck stiffness
• Mood swings or sudden personality changes
• Confusion or agitation
• Seizures
• Memory loss (amnesia)
• Headaches which are sudden and severe
• Passing out or fainting
• Coma

Are There Any Warning Signs?

While these are symptoms one has who is prone to this condition. However, often, many may confuse it with other illnesses. It is best to keep an eye out for warning signs. These could be looking out for yourself or your loved one. Note if there is a sudden loss of balance. Look out for sudden vision loss or changes in one or both eyes. Look for a droop on one or both sides of your face, especially when you smile. Raise both arms and see if one arm sags or drops in a way it usually does not. Note for your speech. Are you as fluent? Are you have trouble speaking? If you see any of such signs, start tracking it and talk to your healthcare provider.

Days after announcing that Pope Leo XIV will have surgery to have a lung nodule removed, he got a confirmed diagnosis of lung cancer. According to reports, he underwent surgery to have the lower lobe of his right lung removed.

The update comes as the 71-year-old pontiff's older brother, Louis Prevost, is undergoing treatment for relapsed multiple myeloma. The developments have brought attention to two different cancers affecting the papal family.

Pope Leo XIV's Lung Cancer Diagnosis

The pope underwent the procedure at Rome's Gemelli Hospital on October 13. According to the Vatican, tests confirmed lung adenocarcinoma, a type of cancer that develops in the cells lining the lungs.

The Vatican said in a medical bulletin, "The surgery was successful, and there were no complications."

The operation lasted approximately 90 minutes, and the pope subsequently returned to his hospital room. Pope Leo had announced on October 11 that doctors had discovered a lung nodule during routine medical examinations. He said the abnormality was detected early and that doctors recommended surgery to remove it.

"Dear friends, during some recent medical examinations, the doctors found a small, localized nodule in my lung. It was detected at a very early stage and is well-localized," he said.

He added, “The doctors believe it is advisable to intervene, so, following their advice, I have decided to undergo surgery to remove it. The operation is already scheduled for the next few days.”

The Vatican has not yet disclosed Pope Leo's cancer's stage or whether it has metastatised to other parts of the body. Further testing, including examination of the lymph nodes, will help doctors determine the extent of the disease and whether additional treatment is necessary.

Also read: Pope Leo XIV Will Undergo Lung Nodule Surgery: When Does Removal Become Necessary

What Is Lung Adenocarcinoma?

Lung adenocarcinoma is the most common type of lung cancer. It develops in glandular cells that produce substances like mucus. It is classified as a non-small cell lung cancer.

Although it is frequently linked with smoking, it can also occur in people who have never smoked. Other risk factors include exposure to radon, second-hand smoke and certain workplace carcinogens.

Symptoms may include a persistent cough, coughing up blood, chest pain, breathlessness and unexplained weight loss. Early-stage disease may cause no noticeable symptoms but it can be detected through imaging and scans.

Treatment largely depends on the cancer's stage, location and characteristics of the tumour. Surgery to remove the affected portion of the lung is a common treatment strategy when the tumour is localised. Chemotherapy, immunotherapy or targeted therapies may be considered depending on further findings.

In Pope Leo's case, the lower lobe of his right lung was removed. The results of further tests will help establish whether surgery alone is sufficient.

Also read: How Does Second-hand Smoke Exposure Increase The Risk Of Lung Cancer In People Who Have Never Smoked Themselves?

Pope's Brother Louis Prevost's Multiple Myeloma Relapsed

Meanwhile, the pope's older brother, Louis Prevost, is receiving treatment for multiple myeloma, a blood cancer that affects plasma cells in the bone marrow. His wife, Deborah Prevost, told CBS News that he was first diagnosed in 2017.

Treatment in 2019, which included stem cell treatment and participation in a clinical trial, helped keep the disease at a "very low level".

However, she said he "fell out of remission" approximately three months ago. He is now participating in another clinical trial at a local hospital in Florida.

Multiple myeloma develops when abnormal plasma cells multiply in the bone marrow, interfering with normal blood cell production and damaging bones and kidneys.

Symptoms can include bone pain, fatigue, frequent infections, anaemia and kidney problems.

Unlike lung adenocarcinoma, which forms a solid tumour in lung tissue, multiple myeloma is a cancer of plasma cells. It is generally considered treatable but not usually curable, and the disease can return after periods of remission.

Speaking about the family's situation, Deborah said, "We keep praying, keeping spirits up for both of them."

The Ebola outbreak in the Democratic Republic of Congo (DRC) has surpassed 9,000 confirmed cases and 4,300 deaths, making it the deadliest outbreak in the country's history. Meanwhile, Kenya has reported no new infections after testing 293 samples following its first confirmed case linked to the outbreak.

According to data released by Congo's public health institute on October 13, the country has recorded 9,066 confirmed Ebola cases and 4,381 deaths.

Health authorities continue to struggle to contain transmission across multiple hotspots in the country. The outbreak, declared in May 2026, is caused by the Bundibugyo strain of the Ebola virus, which has no approved vaccine or specific treatment yet. The epidemic has surpassed Congo's previous worst outbreak, which occurred between 2018 and 2020.

The outbreak is now the second-largest Ebola epidemic globally, after the 2014-2016 West African outbreak, which infected more than 28,600 people and killed over 11,000 across Guinea, Liberia and Sierra Leone.

Kenya Reports No New Cases

Kenya confirmed its first imported case of Ebola on October 6, after a Kenyan national who had travelled from Congo through Uganda died in Nairobi on October 5.

According to Health Minister Aden Duale, the patient fell ill about a month ago and was treated at several hospitals in the DRC before traveling to Nairobi. The patient died days after arriving in the Kenyan capital, according to Reuters.

Kenyan health authorities have placed the country on high alert and are monitoring for possible additional cases. At least 28 contacts, including family members and healthcare workers who cared for the patient, have been identified.

The country's Ministry of Health said on October 11 that 293 samples had been tested since the patient's death and no new infections were detected. The tests covered 289 alerts and only the initial confirmed case tested positive.

Authorities have continued contact tracing and monitoring people who may have been exposed to the virus. Kenya is also strengthening surveillance and public health measures to prevent further transmission.

Also read: Congo Ebola Cases Top 8,000; Deaths Near 4,000 As Treatment Delays Remain A Concern

A Challenging Outbreak

The spread of Ebola has been difficult to contain amid Congo's fragile healthcare infrastructure, insecurity, population movement and challenges in implementing response measures. Health officials are also concerned about transmission in communities outside treatment centres.

The outbreak has affected multiple provinces in eastern Congo, raising concerns about further international spread. Uganda previously reported cases linked to the epidemic but was declared Ebola-free in August.

Although Kenya's latest testing results offer some reassurance, authorities continue to monitor high-risk contacts.

What Is Bundibugyo Virus Disease?

READ: Can Obeldesivir Prevent Ebola Symptoms After Exposure? Drug Trial Moves Forward As Death Toll Crosses 4,000

Bundibugyo virus disease is a rare and deadly illness that has caused outbreaks in several African countries in the past.

It is distinctly different from other known ebolaviruses like the Zaire ebolavirus or Sudan ebolavirus. The 2007 outbreak, where Bundibugyo was detected for the first time, resulted in over 100 cases and was officially declared over in early 2008.

According to the US CDC, the Bundibugyo strain is spread by contact with the blood or body fluids of a person who is infected with or has died from BVD.

It is also spread by contact with contaminated objects (such as clothing, bedding, needles, and medical equipment), or by contact with animals, such as bats and nonhuman primates, that are infected with BVD.

Symptoms include fever, headache, muscle pain, weakness, diarrhea, vomiting, stomach pain, and unexplained bleeding or bruising (a late stage of illness).

Two adults in central North Carolina have died after contracting West Nile virus, prompting health authorities to urge residents to take precautions against mosquito bites as cases continue to rise across the United States.

The North Carolina Department of Health and Human Services confirmed the deaths on October 9, warning that senior citizens and people with underlying health conditions face a higher risk of developing severe illness from the virus.

The US Centers for Disease Control and Prevention (CDC) has reported 11 human cases of West Nile virus in North Carolina this year. The state’s first human case of 2026 was identified in a Gaston County resident in August.

Dr Cameron Wolfe, an infectious disease expert with Duke Health, told WRAL that people infected with the virus may not realise they have it. “If you get West Nile, you probably won't know it,” he said.

Symptoms Of West Nile Virus

Also read: Google Released 3 Million Mosquitoes In Australia, Cutting Pests By 95%: Why US Is Considering It Too

West Nile virus circulates in the environment between mosquitoes, and the species is called Culex. It also circulates via birds. People become infected when the mosquitoes feed on infected birds and then bite people.

The CDC says that people are dead-end hosts, because unlike birds, they do not develop high enough levels of virus in their bloodstream and cannot pass the virus on to other biting mosquitoes.

The virus is rarely transmitted from person-to-person by blood transfusion, organ transplantation, and mother to baby, during pregnancy, delivery, or breastfeeding.

Because the virus can be transmitted through blood and organ transplantation, persons who were recently diagnosed with West Nile virus infection should not donate blood or bone marrow for 120 days following infection.

Symptoms can include fever, headache, body aches, joint pain, vomiting, diarrhoea and rash. In rare cases, the infection can become severe and affect the brain and nervous system, leading to encephalitis or meningitis.

Encephalitis is the inflammation of the brain can cause confusion, altered consciousness, seizures and, in severe cases, coma.

Meningitis is the inflammation of the membranes surrounding the brain and spinal cord can cause severe headaches, fever and neck stiffness.

Acute flaccid paralysis, also one of the complications, occurs when the virus can damage nerve cells controlling muscles, causing sudden weakness or paralysis. In severe cases, respiratory muscles can be affected, leading to breathing failure.

Older adults and people with conditions such as diabetes, high blood pressure, cancer or weakened immunity are at greater risk of developing severe disease.

There is currently no vaccine to prevent West Nile virus infection in humans, and no antiviral treatment is available. Care for severe cases focuses on managing symptoms and complications.

How To Prevent?

Health officials continue to emphasize simple prevention measures as the best defense against WNV. These are:

• Using EPA-approved insect repellents
• Wearing long-sleeved shirts and pants outside
• Adding screens on windows and doors to prevent mosquitoes from entering
• Eliminating standing water within homes, such as flowerpots, gutters, and bird baths

By doing these, residents will be able to drastically lower their chances of infection, particularly when it comes to the active mosquito season.