On Thursday, Uganda confirmed an outbreak of the Ebola virus in its capital city Kampala, with the first confirmed patient dying from it a day before. As per the new developments, the officials are now preparing to deploy a trial vaccine to put an end to this outbreak.

Groups of scientists are working on the vaccine and deployment of more than 2,000 doses of a candidate vaccine against the Sudan strain of Ebola has been planned and confirmed by the Uganda Virus Research Institute. As per the World Health Organization (WHO), Uganda has access to 2,169 doses of trial vaccine. For now, however, there are no approved vaccines for the strain and officials are still investigating the source of the outbreak.

The WHO had also allocated $1 million from its contingency fund for emergencies to support quick action and contain the outbreak in the country.

Confirmed Case

On Wednesday, the Sudan strain of Ebola killed a nurse employed at Kampala's main referral hospital. It is after his death that Ebola was declared an outbreak in the country. Post-mortem samples too have confirmed the Sudan Ebola Virus Disease and at least 44 contacts of the deceased man have been listed for tracing. 30 of these are health workers.

Ebola is a highly infectious hemorrhagic fever, which is transmitted through contact with bodily fluids and tissue. Symptoms include headache, vomiting of blood, muscle pains and bleeding.

it was in the late 2022, when Uganda had last suffered an Ebola outbreak. It killed 55 of the 143 people who were infected and was declared over on January 11, 2023.

What Is Ebola Virus Disease?

As per the WHO, Ebola virus disease (EVD) is a rare but severe illness in humans and is often fatal. People can get infected with the virus if they touch an infected animal when preparing food, or touch body fluids of an infected person such as saliva, urine, faeces or semen, or things that have body fluids of an infected person like clothes or sheets.

How Does Transmission Work?

Ebola enters the body through cuts in the skin or when one is touching their eyes, nose or mouth. Early symptoms include fever, fatigue and headache.

It was first discovered in 1976 in two simultaneous outbreak, when in Nzara, South Sudan and other in Yambuku, Democratic Republic of Congo. The latter occurred near a village near the Ebola River, which is where it gets its name from.

It is highly infectious and transmissible disease, in fact, there have been cases of health-care workers who have frequently been infected while treating patients with suspected or confirmed Ebola. This occurs through close contact with patients when infection control precautions are not practiced strictly.

Cases of people conducted burial ceremonies, involving direct contact with the body of the deceased too can lead to the transmission of Ebola. Even after the long suffering and recovery, there is a possibility of sexual transmission. Pregnant women who get acute Ebola and recover may still carry the virus in their breastmilk, or in pregnancy related fluids and tissues.

Symptoms:

• feeling tired
• headache
• muscle and joint pain
• eye pain and vision problems
• weight gain
• belly pain and loss of appetite
• hair loss and skin problems
• trouble sleeping
• memory loss
• hearing loss
• depression and anxiety

The Cyclospora outbreak that has spread across the US for more than three months has turned deadly, with Michigan—the hardest-hit state—reporting the country's first two deaths linked to the diarrhea-causing parasite.

According to the Michigan Department of Health and Human Services (MDHHS), both individuals had significant underlying health conditions.

"Two deaths have been identified as part of the cyclosporiasis outbreak affecting Michigan. According to medical records, both individuals had significant underlying health conditions that may have been impacted by cyclosporiasis and dehydration," the department said.

Health officials stressed that deaths from cyclosporiasis are rare, as the infection is generally not life-threatening. Michigan has reported 11,234 cases, including 193 hospitalizations.

The US Centers for Disease Control and Prevention (CDC) also confirmed the two outbreak-related deaths in Michigan. As of its July 28 update, the agency has recorded 6,707 laboratory-confirmed cases across 45 states since May 1, along with more than 11,500 suspected cases—primarily in Michigan and Ohio—that are yet to be laboratory confirmed. The outbreak has resulted in 423 hospitalizations.

FDA Links Outbreak to Recalled Iceberg Lettuce

The US Food and Drug Administration (FDA) has linked part of the outbreak to iceberg lettuce supplied by Taylor Farms de Mexico. The company voluntarily recalled affected products on July 17 and said it will no longer source iceberg lettuce from central Mexico for the rest of the growing season.

The recalled lettuce has been linked to illnesses in Indiana, Kentucky, Michigan, Ohio, and West Virginia. Separately, the CDC, FDA, and state health officials are investigating another Cyclospora outbreak linked to iceberg lettuce in nine states, which has sickened at least 1,947 people and hospitalized 98.

Officials are also investigating whether parsley and cilantro may be linked to the outbreak.

What Is Cyclospora?

Cyclospora is a parasite that infects the intestines and is usually spread through contaminated food or water.

Symptoms include:

• Frequent watery diarrhea
• Abdominal cramps
• Bloating
• Nausea
• Excessive gas
• Low-grade fever
• Loss of appetite
• Weight loss

What Should You Do If You Think You Have Cyclosporiasis?

Most infections are mild and resolve without treatment. However, the illness can be prolonged or severe in people with weakened immune systems, who may require antibiotic treatment.

If you develop symptoms:

• See a healthcare provider and request a stool test to confirm a Cyclospora infection.
• Drink plenty of fluids to prevent dehydration caused by diarrhea.
• Because diarrhea can have many causes, getting the right diagnosis is important, as cyclosporiasis is treatable with a specific antibiotic.
• Seek immediate medical attention if you have severe diarrhea, feel dizzy when standing, or have a rapid heartbeat, as these may be signs of serious dehydration.

How Is It Diagnosed and Treated?

Doctors diagnose cyclosporiasis with a stool test that detects the Cyclospora parasite shed in stool.

Although some mild infections may resolve on their own, confirmed cases should be treated with antibiotics. The recommended treatment is the antibiotic trimethoprim/sulfamethoxazole (TMP-SMX).

Your doctor may also recommend:

• Medicines to relieve diarrhea, if appropriate.
• Oral or intravenous fluids to prevent or treat dehydration.

How To Reduce Your Risk

• Check whether recently purchased iceberg lettuce was sourced from Taylor Farms de Mexico, Guanajuato.

• The recall includes:

1. 12-ounce and 24-ounce Iceberg Salad with best-by dates July 18–August 3
2. 8-ounce and 16-ounce Shredded Lettuce with best-by dates July 18–August 3

• Discard or return any recalled products. An additional 33 recalled products were supplied to restaurants and are unlikely to be in home refrigerators.
• No other lettuce varieties, including romaine and butter lettuce, have been linked to the outbreak.
• Avoid eating recalled shredded iceberg lettuce.
• Wash all fresh fruits and vegetables thoroughly under running water, even if labeled pre-washed.
• Choose whole heads of lettuce over bagged greens when possible. Remove the outer leaves and wash the inner leaves thoroughly.
• Cook produce whenever possible, as heat is the most effective way to kill Cyclospora.
• Follow safe food-handling practices and stay updated on food recalls.

An 86-year-old sheep farmer from Wales recently shared how he unknowingly lived with a rare parasitic disease for years before experiencing what he described as "the worst pain" of his life.

The rare case has highlighted a little-known infection that experts say can remain hidden inside the body for decades.

Meredydd Jones, from Trecastle in Powys, was diagnosed with hydatid disease, a parasitic infection caused by the tapeworm Echinococcus granulosus.

He said that slow-growing cysts had been developing in his lungs for years before he was rushed to the hospital after he complained of severe pain in 2016.

"I hadn't been able to control the pain, and it was more intense than anything I had before," Jones recalled. He later underwent two surgeries in 2018 and 2019 to remove cysts from both lungs, while another cyst in his liver continues to be monitored.

The case comes as Public Health Wales raise concerns that the disease, though uncommon, remains a significant public health issue in sheep-farming regions.

What Is Hydatid Disease?

Hydatid disease, also known as cystic echinococcosis, is caused by the larval stage of the Echinococcus tapeworm.

The parasite typically circulates between dogs and livestock such as sheep and cattle. Humans become accidental hosts after ingesting microscopic tapeworm eggs, usually through contact with infected dogs or contaminated food, water, or soil.

Unlike many infections, hydatid disease develops very slowly and gradually. The parasite forms fluid-filled cysts that most commonly affect the liver and lungs, although they can also develop in the brain, bones, or other organs.

Also read: Milestone In Kala-Azar Treatment: WHO Updates Treatment Guidelines, Recommends Shorter & Safer Regimens

Why Symptoms Take Years To Appear?

According to Dr Chris Williams, consultant epidemiologist at Public Health Wales, the disease can remain hidden for an unusually long time.

"What happens is normally the tapeworm transmits between farm animals like sheep and cows to dogs, and the dogs excrete eggs," he explained. "Unfortunately, if humans ingest the eggs, they can then form cysts within humans."

He added that symptoms may not appear for 10 to 20 years, which is why infections are often discovered only after cysts become large enough to cause complications. Depending on where the cysts develop, people may experience:

• Persistent abdominal pain or swelling
• Chest pain, chronic cough or shortness of breath
• Unexplained lumps
• Fever if cysts become infected
• Severe allergic reactions if a cyst ruptures

Public Health Wales says hydatid disease is uncommon but can have serious health consequences if left untreated.

Researchers at Aberystwyth University are now studying dogs, livestock and farming practices to better understand whether the parasite is emerging again in parts of Wales.

The project includes analysing dog faecal samples and tracking farm dogs to understand how the parasite may spread between farms. Experts say prevention remains the most effective strategy.

Regular deworming of dogs, proper disposal of livestock carcasses, avoiding feeding dogs raw offal, and practising good hand hygiene after handling animals can significantly reduce the risk of infection.

Tiny plastic particles may be making their way into one of the body's most protected organs, the brain, according to new research. This has raised concerns about the long-term health effects of microplastic exposure, particularly on brain health.

In a study published in Nature Medicine, researchers found that microplastics and nanoplastics were present in brain tissue, with significantly higher concentrations than in liver and kidneys.

One of the most important findings is that these particles can cross the blood-brain barrier, a protective shield that normally blocks harmful substances from entering the brain.

The researchers analysed brain tissue samples collected over several years and observed that they contained seven to 30 times more plastic particles than other organs.

They also found an increase in brain plastic concentrations in more recent samples, reflecting the growing burden of plastic pollution worldwide in the last few years.

"Our data suggest a trend of increasing concentrations of micro- and nanoplastics in the brain," the study authors wrote. They stressed that the findings do not prove these particles cause disease.

Could Microplastic Exposure Increase Dementia Risk?

The researchers also reported higher concentrations of plastic particles in brain tissue from people diagnosed with dementia.

However, they cautioned that the study only identified an association and cannot determine whether microplastics contribute to dementia or whether brains diseased with dementia simply accumulate more particles.

Scientists are still trying to understand how these particles do harm once they reach the brain. Proposed theories include triggering inflammation, disrupting communication between nerve cells, or affecting blood flow, but none have yet been confirmed in humans.

Also read: Risks Of Plastic Pollution: Study Finds Microplastics In Heart Arteries Can Cause Severe Heart Attacks

How Can Microplastics Get Into The Brain?

Since nanoplastics are extremely small, researchers believe some may pass through the blood-brain barrier and become trapped in brain tissue.

The study found polyethylene, commonly used in food packaging and plastic bottles, was the most abundant type detected in the brain tissue.

Scientists emphasise that it is too early to conclude that microplastics directly damage the human brain.

"The findings are concerning, but they should not be interpreted as proof that microplastics cause neurological disease," the researchers emphasised. More studies are needed to determine whether the particles themselves are harmful or simply markers of environmental exposure.

Also read: Dementia Progression Observed To Slow Down When You Do This Exercise 3 Times A Week

How To Reduce Exposure To Microplastics?

While eliminating exposure entirely is nearly impossible, experts recommend practical steps that may lower intake:

• Avoid heating food in plastic containers.
• Choose glass or stainless steel for food and water storage when possible.
• Reduce consumption of heavily packaged and ultra-processed foods.
• Improve indoor ventilation and reduce household dust, another potential source of airborne microplastics.

The study adds to mounting evidence that microplastics are no longer just an environmental issue. They are increasingly being detected throughout the human body, including the blood, lungs, placenta and now the brain.