On Thursday, Uganda confirmed an outbreak of the Ebola virus in its capital city Kampala, with the first confirmed patient dying from it a day before. As per the new developments, the officials are now preparing to deploy a trial vaccine to put an end to this outbreak.
Groups of scientists are working on the vaccine and deployment of more than 2,000 doses of a candidate vaccine against the Sudan strain of Ebola has been planned and confirmed by the Uganda Virus Research Institute. As per the World Health Organization (WHO), Uganda has access to 2,169 doses of trial vaccine. For now, however, there are no approved vaccines for the strain and officials are still investigating the source of the outbreak.
The WHO had also allocated $1 million from its contingency fund for emergencies to support quick action and contain the outbreak in the country.
On Wednesday, the Sudan strain of Ebola killed a nurse employed at Kampala's main referral hospital. It is after his death that Ebola was declared an outbreak in the country. Post-mortem samples too have confirmed the Sudan Ebola Virus Disease and at least 44 contacts of the deceased man have been listed for tracing. 30 of these are health workers.
Ebola is a highly infectious hemorrhagic fever, which is transmitted through contact with bodily fluids and tissue. Symptoms include headache, vomiting of blood, muscle pains and bleeding.
it was in the late 2022, when Uganda had last suffered an Ebola outbreak. It killed 55 of the 143 people who were infected and was declared over on January 11, 2023.
As per the WHO, Ebola virus disease (EVD) is a rare but severe illness in humans and is often fatal. People can get infected with the virus if they touch an infected animal when preparing food, or touch body fluids of an infected person such as saliva, urine, faeces or semen, or things that have body fluids of an infected person like clothes or sheets.
Ebola enters the body through cuts in the skin or when one is touching their eyes, nose or mouth. Early symptoms include fever, fatigue and headache.
It was first discovered in 1976 in two simultaneous outbreak, when in Nzara, South Sudan and other in Yambuku, Democratic Republic of Congo. The latter occurred near a village near the Ebola River, which is where it gets its name from.
It is highly infectious and transmissible disease, in fact, there have been cases of health-care workers who have frequently been infected while treating patients with suspected or confirmed Ebola. This occurs through close contact with patients when infection control precautions are not practiced strictly.
Cases of people conducted burial ceremonies, involving direct contact with the body of the deceased too can lead to the transmission of Ebola. Even after the long suffering and recovery, there is a possibility of sexual transmission. Pregnant women who get acute Ebola and recover may still carry the virus in their breastmilk, or in pregnancy related fluids and tissues.
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The Ebola outbreak in the Democratic Republic of the Congo (DRC) has reached another concerning milestone. With a surging number of deaths and confirmed infections, the healthcare workers in the affected regions have threatened to declare a strike due to nonpayment of dues, making it challenging to contain a deadly and aggressive outbreak.
According to Reuters, the total confirmed number of deaths due to Bundibugyo Ebola has reached 600, with 1,759 confirmed infections as of July 9.
This comes amid protests demonstrated by healthcare workers in the affected regions, who have threatened to walk off the job due to months of unpaid wages and unsafe working conditions.
The outbreak initially affected Ituri, North Kivu and South Kivu provinces, but authorities are now investigating suspected cases in Tshopo province, including Kisangani, sparking concerns that new areas may be affected.
The outbreak, caused by the Bundibugyo species of the Ebola virus, has been spreading rapidly since it was declared on May 15.
Unlike the Zaire strain, there is currently no approved vaccine or specific treatment for Bundibugyo Ebola virus, making containment and treatment efforts particularly challenging. Currently, experimental therapies are being examined through ongoing clinical trials.
The worsening outbreak could be even more challenging to contain as the frontline healthcare workers, including treatment staff, laboratory personnel, and burial teams, have been protesting nonpayment of salaries, insufficient protective equipment, and difficult working conditions.
According to several reports, many workers say they have not been paid since the outbreak began nearly two months ago. While some have already stopped working, others have warned that a mass walkout could further weaken the country’s Ebola response.
The administrative disruption significantly threatens critical epidemic operations like patient care, lab testing, contact tracing, and safe burial procedures, all of which are essential for slowing transmission and effectively containing the outbreak.
The World Health Organization has repeatedly warned that the outbreak remains in an “expansion phase” due to several reasons, including overwhelmed treatment facilities, population movement, and delays in identifying and isolating infected individuals.
WHO also said that the treatment centers in some of the hardest-hit regions are operating near 90% capacity. Infection cases among healthcare workers are another concern that highlights the risks faced by frontline responders.
Misinformation about the disease has been rife in several Congolese communities. According to the Council on Foreign Relations, there have been reports that some local communities believe that the disease is a hoax or was brought into the country by Western aid workers who wanted to make a profit.
While Ebola is not a new disease, the current outbreak poses a significant threat because it is caused by a rare strain of the virus, Bundibugyo. The rarity of the strain has created scientific and emergency public health challenges, as there is currently no licensed vaccine to protect against the Bundibugyo Ebola virus.
Credit: iStock/Novo Nordisk
Danish pharmaceutical giant Novo Nordisk has launched Awiqli (insulin icodec) in India, introducing the world's first once-weekly basal insulin for adults with diabetes.
Individuals with Type 2 diabetes require daily insulin to manage their blood glucose when diet, exercise, and oral medications are no longer sufficient.
The daily basal insulin injections are typically taken once every 24 hours. But Awiqli is designed to provide background insulin support throughout the week, reducing the number of injections from 365 per year to 52, Novo said.
More than 101 million people in India are living with diabetes, while another 136 million have prediabetes, Novo said in a statement.
Insulin initiation in India is delayed by an average of 7-9 years, partly due to fear of injections, anticipated pain, and cost concerns, it said.
"We believe Awiqli will reduce the psychological and physical barriers to insulin initiation," Novo Nordisk India Managing Director Vikrant Shrotriya said.
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Awiqli (insulin icodec) is a long-acting basal insulin designed to help adults with diabetes maintain stable blood sugar levels with just one injection every week. It is administered using the Awiqli FlexTouch pen on the same day each week.
The treatment is intended to simplify insulin therapy, potentially improving treatment adherence among people who struggle with daily injections.
Earlier this year, the US Food and Drug Administration (FDA) approved Awiqli (insulin icodec-abae) 700 units/mL as the first and only once-weekly basal insulin for adults with type 2 diabetes. The therapy is indicated as an adjunct to diet and exercise to improve glycemic control.
The approval offers a new treatment option for patients seeking an alternative to daily basal insulin, allowing diabetes care to be tailored to different lifestyles and treatment preferences.
"Awiqli may address challenges associated with the frequency of daily basal injections by reducing them from seven to one per week. It is an important advancement for adults with type 2 diabetes who may benefit from an alternative treatment option," said Anna Windle, Group Vice President, Clinical Development, Medical & Regulatory Affairs at Novo Nordisk Inc.
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The therapy has now been launched in India. Awiqli has also received regulatory approval in the US, the European Union, and 13 other countries, with indications varying according to local regulatory approvals.
The approval is supported by Novo Nordisk's ONWARDS Phase 3a clinical program, which enrolled nearly 2,680 adults with uncontrolled type 2 diabetes across four randomized, active-controlled trials.
The studies compared once-weekly Awiqli with daily basal insulin and demonstrated effective reductions in HbA1c, a key measure of long-term blood sugar control. The overall safety profile was found to be consistent with existing daily basal insulin therapies.
Awiqli is prescribed for adults with diabetes and should be used exactly as directed by a healthcare professional.
Patients should inject the medicine once every week on the same day. The dosage should not be adjusted without medical advice, the company said.
Like other insulin therapies, Awiqli may cause side effects, including:
Patients are advised to monitor their blood sugar regularly and seek immediate medical attention if they experience symptoms of severe allergic reactions or persistent hypoglycemia.
Do not take Awiqli if you:
Credit: iStock
Global cancer cases could reach nearly 35 million a year by 2050, without urgent action to improve cancer prevention, early diagnosis and access to treatment, according to the World Health Organization (WHO) Global Status Report on Cancer 2026.
The report warns that cancer remains the world's second leading cause of death, claiming more than 26,000 lives every day and nearly 10 million annually.
The report, jointly released by the WHO and the International Agency for Research on Cancer (IARC), warned that major inequalities in cancer prevention, diagnosis, treatment and supportive care continue to leave millions of people without access to life-saving services.
It also noted that ageing populations, population growth and persistent health inequalities are driving the cancer cases.
"Cancer is a deeply personal disease that touches nearly all of us. But whether a person survives cancer should never depend on where they were born or what they earn," said WHO Director-General Dr Tedros Adhanom Ghebreyesus.
"The inequities documented in this report are not inevitable; they are the consequence of choices, and they can be reversed through stronger and unified action."
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The report highlights major disparities in cancer outcomes.
Beyond its health impact, cancer also creates significant economic and emotional challenges.
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The report shows that the burden of cancer varies significantly across regions.
Although home to only about 9% of the world's population, Europe accounts for:
Many African countries continue to experience comparatively lower cancer incidence but disproportionately higher mortality because of delayed diagnosis and limited access to treatment.
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According to the WHO report:
The report estimates that almost 40% of cancer cases worldwide are linked to preventable risk factors, including:
The WHO has urged governments, health organizations, researchers and the private sector to work together to strengthen cancer care through three broad priorities:
Better capabilities
Better protections
Better value
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