Ebola Outbreak: Uganda Set To Start Vaccine Trials

Updated Feb 3, 2025 | 08:58 AM IST

SummaryAfter a nurse died of the Ebola virus, the country has declared Ebola outbreak and is now deploying vaccine against the Sudan strain of the virus.
Ebola vaccines

On Thursday, Uganda confirmed an outbreak of the Ebola virus in its capital city Kampala, with the first confirmed patient dying from it a day before. As per the new developments, the officials are now preparing to deploy a trial vaccine to put an end to this outbreak.

Groups of scientists are working on the vaccine and deployment of more than 2,000 doses of a candidate vaccine against the Sudan strain of Ebola has been planned and confirmed by the Uganda Virus Research Institute. As per the World Health Organization (WHO), Uganda has access to 2,169 doses of trial vaccine. For now, however, there are no approved vaccines for the strain and officials are still investigating the source of the outbreak.

The WHO had also allocated $1 million from its contingency fund for emergencies to support quick action and contain the outbreak in the country.

Confirmed Case

On Wednesday, the Sudan strain of Ebola killed a nurse employed at Kampala's main referral hospital. It is after his death that Ebola was declared an outbreak in the country. Post-mortem samples too have confirmed the Sudan Ebola Virus Disease and at least 44 contacts of the deceased man have been listed for tracing. 30 of these are health workers.

Ebola is a highly infectious hemorrhagic fever, which is transmitted through contact with bodily fluids and tissue. Symptoms include headache, vomiting of blood, muscle pains and bleeding.

it was in the late 2022, when Uganda had last suffered an Ebola outbreak. It killed 55 of the 143 people who were infected and was declared over on January 11, 2023.

What Is Ebola Virus Disease?

As per the WHO, Ebola virus disease (EVD) is a rare but severe illness in humans and is often fatal. People can get infected with the virus if they touch an infected animal when preparing food, or touch body fluids of an infected person such as saliva, urine, faeces or semen, or things that have body fluids of an infected person like clothes or sheets.

How Does Transmission Work?

Ebola enters the body through cuts in the skin or when one is touching their eyes, nose or mouth. Early symptoms include fever, fatigue and headache.

It was first discovered in 1976 in two simultaneous outbreak, when in Nzara, South Sudan and other in Yambuku, Democratic Republic of Congo. The latter occurred near a village near the Ebola River, which is where it gets its name from.

It is highly infectious and transmissible disease, in fact, there have been cases of health-care workers who have frequently been infected while treating patients with suspected or confirmed Ebola. This occurs through close contact with patients when infection control precautions are not practiced strictly.

Cases of people conducted burial ceremonies, involving direct contact with the body of the deceased too can lead to the transmission of Ebola. Even after the long suffering and recovery, there is a possibility of sexual transmission. Pregnant women who get acute Ebola and recover may still carry the virus in their breastmilk, or in pregnancy related fluids and tissues.

Symptoms:

  • feeling tired
  • headache
  • muscle and joint pain
  • eye pain and vision problems
  • weight gain
  • belly pain and loss of appetite
  • hair loss and skin problems
  • trouble sleeping
  • memory loss
  • hearing loss
  • depression and anxiety

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US Probing Possible Hantavirus Case In Illinois Not Linked To Cruise Ship Outbreak

Updated May 13, 2026 | 01:46 PM IST

SummaryAccording to the World Health Organization (WHO), 11 cases — including three deaths — have been confirmed so far. However, additional suspected and confirmed cases are continuing to emerge across countries.
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Amid the scare of hantavirus infection, US health officials informed that they are investigating a potential case in an Illinois resident.

The Illinois Department of Public Health (IDPH) noted that the incident is not linked to the MV Hondius cruise ship outbreak.

MV Hondius had 18 American nationals, and all have been medically evacuated back to the US. While 16 people are in Nebraska at the nation's only national quarantine unit, two people are being monitored in Atlanta.

In a statement, the IDPH said that the person “lives in Winnebago County, has not travelled internationally, and has not come in contact with individuals associated with the MV Hondius outbreak”.

Officials suspect that the possible hantavirus infection in the Illinois person to be a case of the North American strain of the virus while cleaning a home where rodent droppings were present.

“Unlike the Andes strain of Hantavirus responsible for the cruise outbreak, the North American strains are not known to spread from person to person. The risk of contracting Hantavirus of any kind remains very low for Illinois residents,” the officials said.

However, they added that the CDC is conducting additional testing to confirm that the resident is positive for Hantavirus. CDC staff told IDPH its confirmatory test result could take up to 10 days to complete.

Hantavirus Cases In The US

Excluding this latest potential case, Illinois has had 7 positive cases of Hantavirus since 1993, most recently in March 2025.

Since surveillance began in 1993, the US has recorded 890 cases of Hantavirus over 30 years (1993-2023)

The Hantavirus strain most commonly seen in the US is caused by exposure to rodent droppings and is NOT contagious from person to person.

The rodent species (long-tailed pygmy rice rat) known to carry the Andes strain of the virus in South America does not live in the U.S.

First Case Of Hantavirus Diagnosed In Israel

Also read: Donald Trump Says Hantavirus Is 'Under Control'; Questions Grow Over CDC Research Cuts

Earlier, a case of hantavirus was also reported from Israel, that was not linked to the MV Hondius ship.

The case in Israel, reported by the local newspaper Maariv, is believed to have been infected during a stay in Eastern Europe several months ago. It is reportedly not linked to the ongoing outbreak linked to the MV Hondius cruise ship in the Atlantic Ocean.

The patient underwent an antibody test after the symptoms appeared, which showed exposure to hantavirus, the report said. A PCR (polymerase chain reaction) test was then conducted to detect the virus’s genetic material, confirming the infection, the report said.

The patient was said to be in stable condition, not in need of intensive care or strict isolation, and was being kept under medical observation.

Details about the patient and the medical center where the diagnosis was made could not yet be published, but have been reported to the country's Health Ministry.

Will Hantavirus Become A Public Health Threat?

Also read: Fact Check: Can Ivermectin Help Treat Hantavirus?

Hantavirus is primarily transmitted through contact with infected rodents or exposure to their urine, droppings, and saliva, though rare cases of person-to-person transmission have also been reported.

According to the World Health Organization (WHO), 11 cases — including three deaths — have been confirmed so far. However, additional suspected and confirmed cases are continuing to emerge across countries.

“At the moment, there is no sign that we are seeing the start of a larger outbreak,” said Tedros Adhanom Ghebreyesus, WHO Chief, in the latest media briefing.

However, he said that the situation could still change.

“Given the long incubation period of the virus, we might see more cases in the coming weeks,” he said.

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PCOS Is Now PMOS: What The Name Change Means For Millions Of Women

Updated May 13, 2026 | 12:00 AM IST

SummaryPMOS reflects a major shift in understanding the condition. It now acknowledges that the condition involves endocrine health, metabolic health, reproductive health, dermatological health and psychological health.
PCOS Is Now PMOS: What The Name Change Means For Millions Of Women

Credit: AI generated image

Polycystic Ovary Syndrome (PCOS), a condition affecting more than 170 million women worldwide, has now been officially renamed Polyendocrine Metabolic Ovarian Syndrome (PMOS), according to a global study published today in The Lancet.

The new name reflects a major shift in understanding the condition — from being viewed primarily as a gynecological disorder to being recognized as a complex, multisystem condition affecting several aspects of health.

The new term PMOS acknowledges that the condition involves:

  • Endocrine health
  • Metabolic health
  • Reproductive health
  • Dermatological health
  • Psychological health
“Renaming this condition is more than semantics; it’s about finally recognizing the full reality of what patients experience,” said Melanie Cree, pediatric endocrinologist at the University of Colorado Anschutz and part of the global study.

“For too long, the narrow definition of PCOS has overlooked its metabolic and hormonal complexity, leaving many patients undiagnosed or misunderstood,” Cree added.

Why Was PCOS Renamed To PMOS?

Calls to rename PCOS date back to the 1990s and early 2000s. In 2012, the U.S. National Institutes of Health (NIH) recommended a name change after experts concluded that the term PCOS was misleading and confusing for both patients and healthcare providers.

“The name focuses on a criterion — polycystic ovarian morphology — which is neither necessary nor sufficient to diagnose the syndrome,” NIH experts wrote in the report.

Although PCOS has long been understood as a metabolic condition, experts said the name inaccurately narrowed its scope and overemphasized ovarian cysts and fertility issues.

This often led to:

  • Delayed diagnoses
  • Fragmented care
  • Stigma
  • Missed opportunities for early intervention
“It was very clear that the name was inaccurate,” said Dr. Helena Teede, endocrinologist and professor of women’s health at Monash University in Australia, who chaired the steering group behind the renaming initiative.

How Was The Name Change Decided?

The renaming process involved consultations with thousands of patients and healthcare professionals across the world.

The effort was supported by 56 academic, clinical, and patient organizations.

Experts said the transition from PCOS to PMOS will occur over the next three years through a phased global implementation strategy.

What Does PMOS Mean?

The new name aims to explain the condition more accurately and comprehensively.

Polyendocrine means it affects multiple hormones in the body.

Metabolic refers to issues linked to weight, insulin, blood sugar, and heart health.

Ovarian highlights its impact on ovulation and reproductive health.

Syndrome refers to a group of symptoms occurring together.

In simple terms, PMOS is a hormonal and metabolic condition that can affect periods, fertility, skin, mood, weight, and long-term health.

Experts said the new terminology intends to:

  • Reflect the condition’s hormonal complexity
  • Acknowledge its strong metabolic and cardiometabolic effects
  • Continue emphasizing ovarian involvement without over-focusing on fertility
The experts added that the name change “is expected to reshape how the condition is diagnosed, treated, and researched globally.”

According to the study, PMOS could also:

  • Promote earlier and more accurate diagnosis
  • Support more holistic, patient-centered care
  • Reduce stigma associated with fertility-focused terminology
  • Expand research into metabolic and systemic impacts
“Overall goals include greater awareness, enhanced diagnosis, improved care quality and patient satisfaction, and optimized outcomes across the broad features of the condition,” the experts said.

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Hantavirus Cases Climb To 11; WHO Warns Countries Of Further Spread

Updated May 13, 2026 | 12:02 PM IST

Summary​WHO Director-General Tedros Adhanom Ghebreyesus today stated that 9 of the 11 cases have been confirmed as Andes virus, and the other two are probable. He also warned of more cases in the coming weeks, due to the long incubation period of the hantavirus
Hantavirus Cases Climb To 11; WHO Warns Countries Of Further Spread

Credit: X

Hantavirus cases have climbed to 11, including three deaths, WHO Director-General Tedros Adhanom Ghebreyesus said today.

During a media briefing on hantavirus, Tedros stated that all eleven cases are among passengers or crew members onboard the MV Hondius.

Also Read: Hantavirus Can Linger Indoors, Spread Through Contaminated Dust, Says Infectious Disease Expert

“Nine of the eleven have been confirmed as Andes virus, and the other two are probable,” he added.

All suspected and confirmed cases have been isolated and managed under strict medical supervision, minimizing any risk of further transmission.

Tedros said individual countries were now responsible for their citizens after the evacuation, adding: “I hope they will take care of the patients and the passengers, helping them and also protecting their citizens as well. That’s what we expect.”

Will Hantavirus Become A Public Health Threat?

Noting that “at the moment, there is no sign that we are seeing the start of a larger outbreak,” Tedros said the situation could still change.

“Given the long incubation period of the virus, it’s possible we might see more cases in the coming weeks,” he said.

Acclaimed vaccine scientist Prof. Peter Hotez from the Texas Medical Center (TMC) also said more cases could emerge, but ruled out the risk of a major epidemic.

“We might see additional cases, but I don't think this will be a major epidemic beyond the obvious human tragedy of those who lost their lives, and possibly a few others who could still get very sick,” he said in a post on social media platform X.

“New World hantavirus infections are rough stuff. Once symptoms begin, the resulting cytokine storm and ARDS means there's not much of a window before getting patients into an ICU, and often on ECMO (extracorporeal membrane oxygenation), which requires a high level of skill,” Prof. Peter said.

He also linked increasing zoonotic spillovers and rising arthropod-borne illnesses to “climate change pushing animal reservoirs to explore new habitats, together with deforestation and urbanization.”

“It's animals and vectors closer to humans and people coming closer to animals and vectors,” he added.

“I don't think this particular hantavirus outbreak will accelerate much beyond where it is now, but that's not the point.”

Dutch Hospital Quarantines 12 Healthcare Workers

Meanwhile, Radboud University Medical Center (Radboudumc) in the Netherlands has placed 12 employees in quarantine for six weeks as a precaution after incorrect procedures were followed while caring for a hantavirus-infected patient from the Dutch cruise ship.

The hospital said on Monday that the issue involved procedures for drawing and processing blood samples, as well as the disposal of the patient's urine, according to Xinhua news agency.

Also read: Fact Check: Can Ivermectin Help Treat Hantavirus?

“This blood was processed according to standard procedure. Due to the nature of the virus, this blood should have been processed according to a stricter procedure,” Radboudumc said in a statement, without specifying what the stricter measures should have entailed.

Read More: Donald Trump Says Hantavirus Is 'Under Control'; Questions Grow Over CDC Research Cuts

WHO Guidelines On Hantavirus

The WHO recommends that people exposed to hantavirus should be:

  • Monitored actively at a specified quarantine facility
  • Monitored at home for 42 days from the last exposure
Anyone who becomes symptomatic should be isolated and treated immediately.

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