Ebola Outbreak: Uganda Set To Start Vaccine Trials

Updated Feb 3, 2025 | 08:58 AM IST

SummaryAfter a nurse died of the Ebola virus, the country has declared Ebola outbreak and is now deploying vaccine against the Sudan strain of the virus.
Ebola vaccines

On Thursday, Uganda confirmed an outbreak of the Ebola virus in its capital city Kampala, with the first confirmed patient dying from it a day before. As per the new developments, the officials are now preparing to deploy a trial vaccine to put an end to this outbreak.

Groups of scientists are working on the vaccine and deployment of more than 2,000 doses of a candidate vaccine against the Sudan strain of Ebola has been planned and confirmed by the Uganda Virus Research Institute. As per the World Health Organization (WHO), Uganda has access to 2,169 doses of trial vaccine. For now, however, there are no approved vaccines for the strain and officials are still investigating the source of the outbreak.

The WHO had also allocated $1 million from its contingency fund for emergencies to support quick action and contain the outbreak in the country.

Confirmed Case

On Wednesday, the Sudan strain of Ebola killed a nurse employed at Kampala's main referral hospital. It is after his death that Ebola was declared an outbreak in the country. Post-mortem samples too have confirmed the Sudan Ebola Virus Disease and at least 44 contacts of the deceased man have been listed for tracing. 30 of these are health workers.

Ebola is a highly infectious hemorrhagic fever, which is transmitted through contact with bodily fluids and tissue. Symptoms include headache, vomiting of blood, muscle pains and bleeding.

it was in the late 2022, when Uganda had last suffered an Ebola outbreak. It killed 55 of the 143 people who were infected and was declared over on January 11, 2023.

What Is Ebola Virus Disease?

As per the WHO, Ebola virus disease (EVD) is a rare but severe illness in humans and is often fatal. People can get infected with the virus if they touch an infected animal when preparing food, or touch body fluids of an infected person such as saliva, urine, faeces or semen, or things that have body fluids of an infected person like clothes or sheets.

How Does Transmission Work?

Ebola enters the body through cuts in the skin or when one is touching their eyes, nose or mouth. Early symptoms include fever, fatigue and headache.

It was first discovered in 1976 in two simultaneous outbreak, when in Nzara, South Sudan and other in Yambuku, Democratic Republic of Congo. The latter occurred near a village near the Ebola River, which is where it gets its name from.

It is highly infectious and transmissible disease, in fact, there have been cases of health-care workers who have frequently been infected while treating patients with suspected or confirmed Ebola. This occurs through close contact with patients when infection control precautions are not practiced strictly.

Cases of people conducted burial ceremonies, involving direct contact with the body of the deceased too can lead to the transmission of Ebola. Even after the long suffering and recovery, there is a possibility of sexual transmission. Pregnant women who get acute Ebola and recover may still carry the virus in their breastmilk, or in pregnancy related fluids and tissues.

Symptoms:

  • feeling tired
  • headache
  • muscle and joint pain
  • eye pain and vision problems
  • weight gain
  • belly pain and loss of appetite
  • hair loss and skin problems
  • trouble sleeping
  • memory loss
  • hearing loss
  • depression and anxiety

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Thyroid Medicine Recall Gets US FDA’s Highest Risk Rating: What To Know

Updated Sep 25, 2026 | 10:33 AM IST

SummaryThyroid medication has been classified as Class I risk, meaning there is a “reasonable probability that the use of or exposure to a violative product will cause serious adverse health consequences or death.”
Thyroid Medicine Recall Gets US FDA’s Highest Risk Rating: What To Know

Credit: FDA/iStock

Vitruvias Therapeutics’ thyroid medication, recalled nationwide in August, has been elevated to the highest risk level by the US FDA.

The recall was issued because the medication may be superpotent, potentially causing hyperthyroidism (overactive thyroid).

On Wednesday, the FDA updated the recall to Class I, its most serious recall classification. It applies when there is a “reasonable probability that the use of or exposure to a violative product will cause serious adverse health consequences or death.”

Which Thyroid Tablets Have Been Recalled?

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The affected product is:

  • Vitruvias Thyroid Tablets USP 30 mg
  • Lot number: 504950
  • Expiration date: September 30, 2026

In its August 24 recall notice, the company said the tablets were potentially superpotent.

Risks of Superpotent Thyroid Medicines

Millions of people with hypothyroidism rely on thyroid tablets every day to replace hormones their bodies cannot produce.

However, taking superpotent thyroid tablets can cause hyperthyroidism (overactive thyroid). It can force the body's metabolism into overdrive, speeding up organs and bodily functions.

Left untreated, this constant strain can cause serious health complications across multiple systems in the body.

In addition, people taking the medication can be at risk of

  • weight loss,
  • heat intolerance,
  • fatigue,
  • nervousness,
  • muscle weakness,
  • hypertension,
  • chest pain,
  • rapid heart rate,
  • heart rhythm disturbances.

The lot was distributed nationwide in the US to Vitruvias Therapeutics’ direct accounts between January 31 and September 30, 2025. Of 3,655 units released, 1,955 were sold.

Read More: FDA Recalls Popular Thyroid Medication: What Levothyroxine Users Need to Know

Who Is At Greater Risk?

The company identified the following groups as being at greater risk from superpotent thyroid tablets:

  • Elderly people
  • Pregnant women
  • Infants

Excess thyroid hormones in older adults have been associated with adverse outcomes, particularly those affecting the heart.

Vitruvias Therapeutics said it has not received any reports of adverse events known to be linked to the recall.

The company is notifying wholesalers to stop distributing the recalled product and arranging for its destruction.

What Should Patients Do?

Patients taking Thyroid, USP from Lot 504950 should not stop taking it without first contacting their healthcare provider for guidance and/or a replacement prescription.

Hypothyroidism vs Hyperthyroidism

Speaking to HealthandMe, Dr Shruti Kotangale, Consultant Gynaecologist, Obstetrician and Infertility Expert at AIMS Hospital, Dombivli, explained that both conditions are commonly seen in women.

Hypothyroidism occurs when the thyroid is underactive. Symptoms can include tiredness, weight gain, dry skin, hair fall, constipation, feeling cold, a slow heartbeat and low mood or depression.

Hyperthyroidism occurs when the thyroid is overactive. Symptoms may include weight loss, a fast heartbeat, sweating, anxiety, tremors, irritability, frequent bowel movements and difficulty sleeping.

Women should seek medical attention and manage these symptoms without delay.

Common Symptoms Of Thyroid Disorders

Thyroid disorders may cause a range of symptoms, including:

  • Fatigue
  • Cognitive changes
  • Gastrointestinal problems
  • Sensitivity to cold
  • Skin and hair changes
  • Weight changes

How Is Thyroid Disease Diagnosed?

Diagnosis may involve:

  • Physical examination: To check for swelling or nodules in the neck.
  • Blood tests: These may measure TSH, T4 and T3 levels, along with thyroid antibodies when conditions such as Hashimoto’s disease or Graves’ disease are suspected.
  • Ultrasound or thyroid scans may also be used to assess the thyroid’s structure.

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Racing Legend Darrell Waltrip Diagnosed With Frontotemporal Dementia

Updated Sep 25, 2026 | 10:32 AM IST

Summary​According to his family, Darrell Waltrip has FTD, which is being complicated by possible chronic traumatic encephalopathy (CTE), which they believe may be linked to injuries sustained during his racing career from 1972 to 2000.
Racing Legend Darrell Waltrip Diagnosed With Frontotemporal Dementia

Credit: Reuters

American racing champion and NASCAR Hall of Famer Darrell Waltrip has been diagnosed with Frontotemporal Dementia (FTD), his family has announced.

The 79-year-old former NASCAR driver and broadcaster will be stepping further away from public life following the diagnosis.

According to his family, Waltrip has FTD, which is being complicated by possible chronic traumatic encephalopathy (CTE), which they believe may be linked to injuries sustained during his racing career from 1972 to 2000.

“We wanted to share a health update with all of Darrell’s friends and fans who have supported him throughout his racing career. Recently, Darrell has been diagnosed with Frontotemporal Degeneration (FTD) complicated by possible Chronic Traumatic Encephalopathy (CTE) — likely from injuries incurred during his racing career,” the family said in a statement.

The family said Waltrip currently has only “minor noticeable symptoms” and is “happy and otherwise healthy,” spending time with his wife, Stevie, and their two daughters.

Why Can Repeated Head Injuries Raise CTE Concerns?

Chronic traumatic encephalopathy (CTE) is a progressive brain disease believed to be associated with repeated head injuries. It has most commonly been studied in contact-sport athletes and military personnel exposed to repeated head trauma.

Experts are still studying how the number and severity of head injuries contribute to CTE risk. Importantly, not everyone exposed to repeated head injuries develops CTE, and the condition can currently be definitively diagnosed only after death through examination of brain tissue.

A 2026 study led by researchers at Boston University and Harvard Medical School found that roughly one in four former NFL players who died between 2016 and 2021 had CTE.

CTE And Racing

Although CTE has historically received considerable attention in American football and other contact sports, repeated head impacts can occur in motorsports as well.

Waltrip is not alone. NASCAR Hall of Famer Fred Lorenzen was diagnosed with CTE by researchers after he died in 2024.

What Is Frontotemporal Degeneration?

Read More: The First Symptom of Bruce Willis’ Frontotemporal Dementia That Left His Wife Emma Heming Stunned

Frontotemporal degeneration, also known as frontotemporal dementia (FTD), refers to a group of brain disorders that primarily affect the frontal and temporal lobes.

These areas are involved in personality, behavior, language, and other functions. Unlike Alzheimer's disease, memory loss may not be the first or most prominent symptom of FTD.

FTD can develop at a younger age than many other forms of dementia, sometimes affecting people in their 40s or 50s.

The condition can cause changes in:

  • Personality and behavior
  • Judgment and decision-making
  • Emotional responses and empathy
  • Speech and language
  • Movement and coordination
American actor Bruce Willis has also been diagnosed with FTD.

What Are The Symptoms Of FTD?

Symptoms vary depending on which areas of the brain are most affected and generally worsen over time.

Behavioral Symptoms

  • Personality and behavior changes
  • Loss of empathy
  • Poor judgment and impulsivity
  • Socially inappropriate behavior
  • Apathy or loss of interest
  • Repetitive or compulsive behavior
Language Symptoms

  • Difficulty finding words
  • Trouble understanding speech or writing
  • Difficulty naming objects
  • Increasing difficulty speaking
Movement Symptoms

  • Tremors or stiffness
  • Muscle weakness or spasms
  • Poor balance and falls
  • Difficulty swallowing
  • Changes in speech or movement

Darrell Waltrip's Racing Legacy

Waltrip is one of NASCAR's most accomplished drivers, with 84 Cup Series victories and three Cup Series championships.

He won the Daytona 500 in 1989 and the Southern 500 in 1992. He also won the Coca-Cola 600 five times, making him the winningest driver in the race's history.

Waltrip later became a familiar voice in NASCAR broadcasting, working as a commentator for many years.

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UK NHS Trust To Review 4,500 More Breast Cancer Cases After 20 Unnecessary Mastectomies

Updated Sep 24, 2026 | 11:22 PM IST

SummaryThe review could take five years, with women treated in 2015 potentially having their cases reviewed as late as 2031. The review so far costed about £523,000 in its first year and involved nine reviewers examining around 80 cases a month.
UK NHS Trust To Review 4,500 More Breast Cancer Cases After 20 Unnecessary Mastectomies

Credit: iStock

The UK NHS is set to review around 4,500 more breast cancer cases dating back to 2015 after a review found delayed diagnoses and 20 cases involving unnecessary breast removal surgery.

Hundreds of patients suffered harm under County Durham and Darlington NHS Foundation Trust in north-east England., according to the review.

The Trust has apologized and is using specialists from other hospitals to determine whether more women underwent unnecessary operations or received poor care.

"The trust will complete the reviews already under way covering care between January 2023 and February 2025. It will then look back one year at a time, starting with patients treated in 2022 and working backwards towards 2015," it said in a statement.

Review Could Cover 4,500 Cases

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Board chair Alison Marshall apologized to women and families affected by the failings.

"I would like to offer a sincere apology to all the women and their families who have been affected by the failings in our breast services," she said, according to the BBC.

"I can't imagine the impact that has had."

She said the Trust could "not turn back the clock" but would be "open, honest and transparent" about the failings.

Chief nurse Gill Hunt said concerns were first raised in 2015 following a "service reconfiguration" and the loss of breast surgical trainee posts.

Till September 2, 2026, a total of 539 cases had been reviewed, and is expected to examine around 4,500 cases if it extends back to 2015.

The Trust said each year's findings will be "carefully considered" before it moves to the next earlier year. As per the report, the review could take five years, with women treated in 2015 potentially having their cases reviewed as late as 2031.

The admission came after the BBC reported last year that more than 200 patients were found to have suffered harm at the CDDFT.

"We have heard again today about the profound and lasting impact that failings in our breast services have had on women and their families," said Chief executive Steve Russell.

"We remain deeply sorry for the harm and distress caused, and for the times when, as a Trust, we should have listened more carefully, asked more questions and acted sooner," Russell added.

About 640 patients have contacted a special helpline seeking a review of their cases. The current review cost about £523,000 in its first year and involved nine reviewers examining around 80 cases a month.

20 Women Had Unnecessary Mastectomies

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About 514 cases reviewed by the trust so far, between January 2023 and February 2025, alongside the cases of 640 former patients who contacted a dedicated helpline.

Of the 514 cases, 315 patients have been found to have suffered harm, including 77 who were significantly harmed. One patient is known to have died.

The Trust was found to have a high number of mastectomies compared with other NHS trusts, with operations carried out "too quickly".

Breast Cancer Burden In UK

Breast cancer is the most common cancer in the UK, accounting for roughly 15% of all new cancer cases.

Around 60,763 new cases are diagnosed each year, according to Breast Cancer UK. An estimated 14,000-15,000 mastectomies are performed annually in the UK.

What Is A Mastectomy?

A mastectomy is surgery to remove the whole breast. Depending on the cancer, nearby lymph nodes and surrounding tissue may also be removed. It may be performed on one or both breasts depending on the type of cancer and individual risk factors.

Some patients may undergo breast reconstruction after a mastectomy to restore breast shape and symmetry.

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