On Thursday, Uganda confirmed an outbreak of the Ebola virus in its capital city Kampala, with the first confirmed patient dying from it a day before. As per the new developments, the officials are now preparing to deploy a trial vaccine to put an end to this outbreak.

Groups of scientists are working on the vaccine and deployment of more than 2,000 doses of a candidate vaccine against the Sudan strain of Ebola has been planned and confirmed by the Uganda Virus Research Institute. As per the World Health Organization (WHO), Uganda has access to 2,169 doses of trial vaccine. For now, however, there are no approved vaccines for the strain and officials are still investigating the source of the outbreak.

The WHO had also allocated $1 million from its contingency fund for emergencies to support quick action and contain the outbreak in the country.

Confirmed Case

On Wednesday, the Sudan strain of Ebola killed a nurse employed at Kampala's main referral hospital. It is after his death that Ebola was declared an outbreak in the country. Post-mortem samples too have confirmed the Sudan Ebola Virus Disease and at least 44 contacts of the deceased man have been listed for tracing. 30 of these are health workers.

Ebola is a highly infectious hemorrhagic fever, which is transmitted through contact with bodily fluids and tissue. Symptoms include headache, vomiting of blood, muscle pains and bleeding.

it was in the late 2022, when Uganda had last suffered an Ebola outbreak. It killed 55 of the 143 people who were infected and was declared over on January 11, 2023.

What Is Ebola Virus Disease?

As per the WHO, Ebola virus disease (EVD) is a rare but severe illness in humans and is often fatal. People can get infected with the virus if they touch an infected animal when preparing food, or touch body fluids of an infected person such as saliva, urine, faeces or semen, or things that have body fluids of an infected person like clothes or sheets.

How Does Transmission Work?

Ebola enters the body through cuts in the skin or when one is touching their eyes, nose or mouth. Early symptoms include fever, fatigue and headache.

It was first discovered in 1976 in two simultaneous outbreak, when in Nzara, South Sudan and other in Yambuku, Democratic Republic of Congo. The latter occurred near a village near the Ebola River, which is where it gets its name from.

It is highly infectious and transmissible disease, in fact, there have been cases of health-care workers who have frequently been infected while treating patients with suspected or confirmed Ebola. This occurs through close contact with patients when infection control precautions are not practiced strictly.

Cases of people conducted burial ceremonies, involving direct contact with the body of the deceased too can lead to the transmission of Ebola. Even after the long suffering and recovery, there is a possibility of sexual transmission. Pregnant women who get acute Ebola and recover may still carry the virus in their breastmilk, or in pregnancy related fluids and tissues.

Symptoms:

• feeling tired
• headache
• muscle and joint pain
• eye pain and vision problems
• weight gain
• belly pain and loss of appetite
• hair loss and skin problems
• trouble sleeping
• memory loss
• hearing loss
• depression and anxiety

The Ebola outbreak in DR Congo has risen to 1,427 cases, while the death toll has climbed to 440, according to the latest government data.

More than 609 patients are hospitalized in Congo, while many have also recovered. Uganda has so far reported 20 confirmed cases and two deaths. There has also been one case in France and another in a US citizen medically evacuated to Germany, both believed to have been imported from areas affected by the ongoing outbreak.

The Ebola virus disease, caused by the Bundibugyo strain, has no approved vaccine or treatment.

"Even without approved therapeutics, people are recovering from this disease, but, of course, we could save many more lives with safe and effective therapeutics in our toolkit," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General.

He said this while announcing the launch of the clinical trial of two therapeutics, with the enrolment of the first patient.

"The PARTNERS trial will evaluate the monoclonal antibody MBP134 and the antiviral drug remdesivir, alone and in combination," he added.

Also read: Donald Trump Posts AI Video of Himself Treating Critics for 'Derangement Syndrome'

All About the Trial

The study is being coordinated by the DRC's National Institute for Biomedical Research, supported by a coalition of partners including WHO, and conducted in close cooperation with the affected communities.

According to Tedros, patients who enroll in the trial will receive comprehensive supportive care and close follow-up.

"We are also working to ensure they have access to the two drugs should they prove safe and efficacious in the trial."

In addition, the WHO has granted emergency use listing to the first molecular diagnostic test for Bundibugyo virus.

Further, the antiviral drug remdesivir, marketed as Veklury is also expected to start. Remdesivir became widely known during the COVID-19 pandemic and is being evaluated to determine whether it can improve outcomes when combined with the antibody treatment.

As per experts, it could take months, and possibly as many as 1,000 study participants, to determine whether either drug works.

Currently, the study is being offered only at one Ebola treatment center in Congo's Ituri province. The region has been heavily affected by violence, including attacks on healthcare workers responding to a virus spread through contact with infected patients' bodily fluids. Officials plan to expand the trial to other locations once it is safe to do so.

Read More: Australia Reports More H5 Bird Flu Cases: Does It Have Pandemic Potential?

Challenges Remain

Tedros said that despite the progress, significant challenges remain, including mistrust and violence.

This week, an Ebola treatment center in Ituri province was attacked, resulting in the deaths of two people. The center was set on fire, and patients fled.

Such acts not only endanger patients and health workers but also impede efforts to stop transmission and save lives.

He added that the complexity of the outbreak requires close coordination across the United Nations system.

What Is Ebola?

Ebola is a severe and often fatal viral hemorrhagic fever first identified in 1976. Since then, more than 30 outbreaks have been recorded, primarily in Central and West Africa.

Common Symptoms of Ebola

• Fever
• Headache
• Weakness and fatigue
• Vomiting
• Diarrhea
• Muscle pain
• Sore throat
• Unexplained bleeding or bruising.

Amid increasing conversations about Donald Trump suffering from dementia, the US President posted an AI-generated video of himself as a doctor diagnosing celebrities with what he calls "Trump Derangement Syndrome (TDS)."

The clip features AI recreations of Hollywood actors and celebrities, including Whoopi Goldberg, Robert De Niro, Julia Roberts and Rosie O'Donnell, all of whom have previously criticized Trump.

"Have you or someone you know been diagnosed with TDS?" the AI Trump asks at the start of the clip posted on Truth Social.

Calling the "symptoms relentless," the 80-year-old President said that "fortunately, I'm Doctor Trump, and I have a treatment plan," The Independent reported.

Trump's AI Patients Share Their Symptoms

The AI-generated Trump then invited viewers to hear from some of his "patients."

"I couldn't eat, I couldn't sleep, constantly angry…" the fake De Niro said. "I made everyone miserable around me."

"I feel like I've aged 20 years in the last two years," added the AI version of Roberts, claiming that she was starting to "worry about her future."

The fake O'Donnell claimed that she had been "suffering for over a decade," while the AI Goldberg said she believed she was a "lost cause."

Other stars spoofed in the 90-second clip include actors Edward Norton and John Leguizamo, both of whom have criticized the president.

Also read: Norovirus Hits Princess Cruise Ship; US CDC Reports 5th Stomach Bug Outbreak of 2026

'Doctor Trump's Treatment Plan

At the end of the video, "Doctor Trump" revealed his "treatment" plan: "Turn off fake news."

He further instructed the AI patients to: "Say your prayers and, if you ever feel anxious, just have a Diet Coke like me and you're gonna see a remarkable difference in your life."

What Is Trump Derangement Syndrome?

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Trump has often labeled his detractors as having Trump Derangement Syndrome, even claiming in the Oval Office that he had heard it "actually is a disease."

The term is an adaptation of "Bush Derangement Syndrome," which was coined by columnist Charles Krauthammer in 2003.

Krauthammer described the term as "the acute onset of paranoia in otherwise normal people in reaction to the policies, the presidency—nay—the very existence of George W. Bush."

Trump's Health Under Scrutiny

Read More: New Book Examines Donald Trump's Health, Age Concerns; White House Responds

Trump, who became the oldest US president in history after turning 80 this year, has faced growing public scrutiny over his health.

Recent public appearances have prompted speculation after observers noted swollen ankles, bruising on his hands, verbal slips and occasional episodes in which he appeared drowsy during meetings and international summits.

Some physicians have also publicly expressed concerns about the president's physical and cognitive health, although none have diagnosed him with dementia.

But Trump has repeatedly rejected allegations of cognitive decline or other serious health issues. His most recent annual physical examination also concluded him to be "in excellent health."

The White House also maintains that: "President Trump is the sharpest and most accessible President in American history who is working nonstop to solve problems and deliver on his promises."

The US Centers for Disease Control and Prevention (CDC) has reported another norovirus outbreak aboard a Cruise ship that has sickened nearly 125 people.

So far this year, the CDC has reported seven outbreaks on cruise ships under its jurisdiction, five of which were caused by norovirus.

Nearly 125 People Fall Ill

The outbreak occurred aboard the Ruby Princess during a 20-day voyage along the west coast of North America.

According to the CDC, 102 passengers and 23 crew members reported gastrointestinal illness during the voyage.

The outbreak was first reported to the CDC's Vessel Sanitation Program on June 28.

The Ruby Princess was carrying more than 3,000 passengers and 1,144 crew members during the outbreak.

According to the CDC, Princess Cruises and the ship's crew implemented increased cleaning and disinfection procedures under the company's outbreak prevention and response plan.

Crew members also collected stool specimens from affected individuals for testing, isolated ill passengers and crew members, and consulted with the CDC's Vessel Sanitation Program.

Also read: Australia Reports More H5 Bird Flu Cases: Does It Have Pandemic Potential?

What Is Norovirus?

Norovirus is a highly contagious virus that causes gastroenteritis, leading to inflammation of the stomach and intestines.

Speaking to HealthandMe, epidemiologist Dr. Amitav Banerjee, professor at DY Patil Vidyapeeth, Pune, described norovirus as “notorious because it spreads very fast.”

“It can spread through fomites like handles and knobs, and even a very low infectious dose—around 18 viral particles—can cause infection. So it spreads very fast,” he said.

He added that while many common disinfectants are ineffective against it, norovirus can be inactivated using bleach and chlorine-based cleaning agents.

Is The Norovirus Outbreak Of Concern?

Although outbreaks can look alarming, Dr. Banerjee emphasized that norovirus infections are generally self-limiting.

“In the ship, it can be managed with oral rehydration, and in severe cases, IV fluids can help prevent complications and mortality,” he said.

Dr. Banerjee also clarified that, unlike diseases with pandemic potential, norovirus outbreaks—while explosive in nature—do not typically pose a long-term global threat.

"Norovirus is a stomach infection contracted through the consumption of contaminated food or water or through contact with an infected individual. The infection is highly contagious, but not life-threatening, and is manageable with proper care and hydration," Dr Suresh Kumar D, Senior Specialist - Infectious Diseases, Apollo Speciality Hospitals, Vanagaram, Chennai, told HealthandMe.

Who Is Most at Risk? What Are The Key Symptoms

Dr. Banerjee noted that extreme age groups, especially very young infants and the elderly, are at higher risk due to dehydration from diarrheal illness. However, deaths remain rare when proper care is provided.

Norovirus illnesses usually last between two and three days. Symptoms usually begin suddenly within 12 to 48 hours of exposure and may include:

• Nausea
• Vomiting
• Watery diarrhea
• Stomach cramps
• Low-grade fever
• Headache and body aches
• Fatigue

What You Can Do To Stop Its Spread

Because of how fast viruses spread, experts highly recommend preventive actions such as:

• Wash your hands frequently with soap and warm water, especially after using the toilet or before preparing food.
• Avoid visiting hospitals or care homes if experiencing symptoms.
• Stay home for at least 48 hours after symptoms subside to prevent spreading the virus.