Do You Think You Have High Alcohol Tolerance? Here’s How Liquor Impacts Your Brain Activity

Updated Aug 9, 2024 | 03:00 PM IST

SummaryA recent research sheds light on social drinkers and how even moderate alcohol consumption can impact brain activity, challenging the notion that occasional drinking is harmless.
Liquor Impacting Brain Activity (Credit-Freepik)

Liquor Impacting Brain Activity (Credit-Freepik)

Many of us believe that we are great drinkers and that alcohol does not affect us as much. People who are able to drink without showing any sign of inebriation are known as social drinkers. In short, they are not addicted to alcohol but will not turn down the opportunity to have a good time! While it may seem like it doesn’t affect you, new studies suggest that it is just an illusion, even if you have high tolerance, alcohol affects your cognitive and motor functions more than you think.

The study reveals the below implications and techniques:

  • Researchers used a new MRI technique to precisely measure brain electrical activity.
  • By comparing brain scans before and after drinking, scientists identified specific areas affected by alcohol and how much brain activity slowed down.
  • Participants were chosen to be regular social drinkers without alcohol addiction, ensuring the study focused on the effects of alcohol alone.
  • MRI technology provided reliable data on brain activity changes caused by alcohol consumption.

How does the brain react to alcohol?

The human brain is a complex network of billions of neurons that communicate through electrical impulses. Brain conductivity refers to the efficiency with which these electrical signals travel through brain tissue. It's akin to the speed and clarity of a digital signal through a wire. In layman terms, your brain must function in its peak condition as it is essential for various cognitive processes, including memory, attention, decision-making, and motor control.

Think of it as the foundation for your brain's performance. When brain conductivity is high, information flows smoothly, and that helps your brain in rapid processing and response. On the other hand, low conductivity can hinder cognitive function, leading to slower thinking, impaired memory, and difficulties with coordination.

A study conducted at the Neuroscience Research Australia (NeuRA) and UNSW Science unveiled a startling connection between alcohol consumption and brain conductivity.

What is the connection between alcohol consumption and brain activity?

While many people brush off the effects of alcohol as temporary changes in behaviour, the reality is much more complex. Beyond the obvious impacts on coordination and judgment, alcohol significantly alters brain function. Alcohol dramatically slowed down brain activity, especially in areas responsible for decision-making, planning, and physical coordination. This decline was so significant that it resembled the brain changes seen in normal ageing. This means even one drink could temporarily accelerate the ageing process of your brain.

Alcohol and Brain activity: What does the study Imply?

The implications of this research are far-reaching. It provides compelling evidence that alcohol consumption has a direct and measurable impact on brain function. The discovery that alcohol can significantly reduce brain conductivity opens new avenues for understanding the neurocognitive effects of alcohol abuse and dependence. While you may not feel like alcohol is affecting you and you have a high tolerance, it most definitely changes and affects your decision-making abilities and impulse control.

Furthermore, the MRI technique employed in the study could be a valuable tool for assessing the impact of other substances on the brain and for developing interventions to mitigate alcohol-related brain damage.

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Ebola Cases Cross 6,000, Death Toll Nears 3,000 In Congo; Mortality Rate Remains Close To 50%

Updated Sep 1, 2026 | 07:08 AM IST

SummaryAccording to latest government data, Ebola cases in DR Congo has crossed 6000 with almost 3,000 deaths. The outbreak's case-fatality ratio at approximately 48.2%.
Ebola Cases Cross 6,000, Death Toll Nears 3,000 In Congo; Mortality Rate Remains Close To 50%

Credit: AI

The Ebola outbreak in the Democratic Republic of Congo has crossed another grim milestone, with more than 6,000 confirmed cases and nearly 3,000 deaths. As of August 31, 2026, DRC had reported 6,041 confirmed cases and 2,911 deaths, according to government figures.

That puts the outbreak's case-fatality ratio at approximately 48.2%, meaning nearly one in every two confirmed patients has died. More than 1,360 people have recovered.

With Ituri remaining the epicentre, the outbreak, caused by the Bundibugyo species of Ebola virus, has spread across six provinces and nearly 60 health zones.

Mortality Rate Is Close To 50%

In its latest Disease Outbreak News update, the World Health Organization (WHO) reported a 48.1% crude case-fatality ratio as of August 26 and said the figure “underscores the severity of the disease”.

The number also highlights other issues like timely diagnosis, access to and quality of clinical care and containing transmission. Delayed diagnosis can be particularly dangerous as people may continue interacting with family members and healthcare workers while infectious.

WHO reported that 81 new confirmed cases were recorded in a single 24-hour period as of August 26. Ituri alone had recorded 4,802 confirmed cases by that point.

A nearly 50% case-fatality ratio does not mean that every person infected with Bundibugyo virus has a 50% chance of dying.

It is calculated from recorded cases and deaths and that can change as patients recover, die or are newly diagnosed. It is also be affected by how early cases are detected, access to treatment and whether infections are being missed.

Also read: Ebola Bundibugyo Virus: American Health Worker Had 10x Higher Viral Load In Throat Than Blood

Second-Largest Ebola Outbreak On Record

The US Centers for Disease Control and Prevention (CDC) says, "The DRC outbreak is spreading substantially faster than previous Ebola outbreaks” and is now the second-largest Ebola outbreak on record. The outbreak surpassed 1,000 confirmed cases within about 40 days of response activation, compared with approximately 235 days during the 2018 DRC outbreak.

The CDC says the response is being affected by limited healthcare infrastructure, ongoing conflict, violence against healthcare workers, shortages of protective equipment, population movement, mistrust and misinformation.

WHO Director-General Tedros Adhanom Ghebreyesus has repeatedly stressed that communities need to be at the heart of the response.

In a joint WHO-Africa CDC commentary published on August 25, Tedros, WHO Africa Regional Director Mohamed Yakub Janabi and Africa CDC Director-General Jean Kaseya wrote, “Ebola spreads through communities, and communities hold the knowledge required to stop it.”

Also read: Ebola Outbreak In DR Congo Records Its Highest Weekly Death Tolls Yet, With More Than 300 Deaths

Vaccine-Related Developments

Unlike Zaire strain, this outbreak is being caused by Bundibugyo virus, for which there is currently no vaccine or treatment. But researchers are in the process of testing vaccine and treatment on candidates.

Health authorities have also taken the unusual step of testing Ervebo, the vaccine licensed for Zaire Ebola, against the Bundibugyo strain.

WHO and Africa CDC announced in August that DRC would receive 70,000 Ervebo doses. Of these, 20,000 doses are intended for a Phase 3 clinical trial, while 50,000 are intended for frontline and healthcare workers under current recommendations.

WHO said, “It is not known whether Ervebo may be protective against the Bundibugyo virus in humans.”

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Eli Lilly Moves Beyond GLP-1 Drugs, To Spend 2.88 Billion On Autoimmune Drug Development

Updated Sep 1, 2026 | 06:07 AM IST

SummaryEli Lilly is set to acquire privately-held biotech company Merida Biosciences for up to $2.875 billion in its big move for a big autoimmune drug push.
Eli Lilly Moves Beyond GLP-1 Drugs, To Spend $2.88 Billion On Autoimmune Drug Development

Credit: AI

Eli Lilly has made its latest move to look beyond the blockbuster GLP-1 market by agreeing to acquire biotech company Merida Biosciences for up to $2.875 billion in cash.

The deal will give Lilly access to Merida's experimental treatments for autoimmune and allergic diseases, including a potential drug for Graves' disease and thyroid eye disease. The transaction is expected to be completed in the fourth quarter of 2026, subject to regulatory approvals and other conditions.

The acquisition is another sign that Lilly is trying to diversify its pipeline beyond the obesity and diabetes medicines that have driven its recent growth. Lilly's spending on similar deals in 2026 that signals the company is looking to to expand beyond its successful hold on GLP-1 markets.

From Weight Loss Medications To Autoimmune Disease Drugs

Merida's lead programme, MER511, is currently in Phase 1 development for Graves' disease and thyroid eye disease (TED). The experimental treatment uses Merida's antibody-engineering platform to selectively remove pathogenic autoantibodies, the antibodies responsible for driving certain autoimmune diseases.

The idea is different from conventional immune-suppressing medicines, which dampen immune activity broadly. Initial Phase 1 data showed that MER511 substantially reduced thyroid-stimulating antibodies associated with Graves' disease and TED, while showing a favourable initial safety profile.

Francisco Ramírez-Valle, Lilly's senior vice president of immunology research and early clinical development, said, “We're building our pipeline around therapies that meaningfully change the course of disease, not just its downstream effects.”

He added that Merida's lead programme is designed to selectively and directly target the antibodies driving Graves' disease and thyroid eye disease.

Also read: Eli Lilly’s Foundayo Launched In UK: Is the GLP-1 Pill Better Than Wegovy, Mounjaro?

Different Drug Approach To Autoimmune Disease

In thyroid eye disease, inflammation can cause eye bulging, pain, double vision and, in severe cases, vision impairment.

Lilly's interest is specifically in Merida's approach is its attempt to target the disease-causing antibodies themselves, rather than suppressing the immune system more broadly.

Merida CEO Adam Townsend said, “Merida was founded to fundamentally change how autoimmune and allergic diseases are treated, by targeting the antibodies driving them directly, rather than suppressing the immune system broadly.”

That could potentially offer a more precise way of treating diseases in which specific autoantibodies are driving the damage.

Also read: Wegovy Is The Go-To Weightloss Drug Choice For Most US Teens

Lilly's Expanding Pipeline

The acquisition isn't only about Graves' disease. Merida's pipeline includes MER769, an experimental programme being developed for food allergy, asthma, chronic spontaneous urticaria and other allergic diseases.

The company also has earlier-stage programmes targeting kidney diseases and other conditions mediated by immunity.

This gives Lilly a potential base across a much broader range of immune-mediated diseases. The company that became synonymous with Mounjaro and Zepbound is trying to build a pharmaceutical portfolio that does not cash in entirely on the GLP-1 boom.

MER511 is still only in Phase 1, meaning its safety and preliminary biological activity are being evaluated in early clinical testing. The promising initial data do not yet establish whether the drug will ultimately work in larger patient populations or receive regulatory approval.

The $2.88-billion deal is therefore not Lilly buying an already-proven autoimmune medicine. It is buying a platform and the potential for an entirely new class of treatments.

As Townsend put it, “Joining Lilly gives our science the resources and commitment to realize its potential for patients with immune-mediated conditions.”

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Pharmacies In England To Launch Free 7-Minute Cholesterol Checks: Why Is It Important?

Updated Aug 31, 2026 | 11:00 PM IST

SummaryPeople aged 40 to 84 who are not pregnant and have not had a blood test in the past year will be eligible to walk in and get tested. Eligible people will also be offered a blood pressure check as part of a clinical consultation with a pharmacist prescriber.
Pharmacies in England to Launch Free 7-Minute Cholesterol Checks: Why Is It Important?

Credit: iStock

The NHS in England today announced that 100 pharmacies will offer free cholesterol check-ups beginning this autumn.

The initiative is part of an NHS drive to reduce heart disease and stroke deaths by a quarter over the next decade. It will include free finger-prick blood tests for cholesterol on the high street for the first time.

Who Is Eligible?

People aged 40 to 84 who are not pregnant and have not had a blood test in the past year will be eligible to walk in and get tested.

Eligible people will also be offered a blood pressure check as part of a clinical consultation with a pharmacist prescriber.

The NHS pilot will run until spring 2027.

How Will The Test Be Conducted?

Blood will be taken from a person’s fingertip using a lancet — a small, sharp medical tool used to prick the skin — and analyzed immediately. A pharmacist prescriber can then provide lifestyle advice and determine whether any treatment, such as statins, may be needed.

Patients will receive a copy of their results by email. They will also be offered a blood pressure check as part of a clinical consultation with a pharmacist prescriber.

How Will It Help?

The national rollout follows a successful smaller pilot in north London, which tested 2,493 patients at 61 community pharmacies between January 2025 and March 2026.

Nearly one in five patients were found to be suitable for pharmacological intervention, and 88 people started taking statins.

David Webb, the chief pharmaceutical officer for England, said pharmacies could be a vital first line of defense against serious illness.

He said: “By making it easier for people to get a quick and convenient cholesterol health check on their local high street, we can spot ticking timebombs earlier, helping people take action, and prevent heart attacks and strokes before they happen.

“This is the latest in a series of initiatives involving pharmacies in delivering care previously only offered in GP surgeries as part of the 10-year health plan to bring care closer to where people live.”

Will This Be Scaled Up?

In the first phase of the national rollout, about 100 NHS pharmacies across England will begin offering the checks from this autumn.

Dr Rani Khatib, NHS England’s national specialty adviser for cardiovascular disease prevention, said everyone should strive to be aware of the most common risk factors for heart disease, including high cholesterol and blood pressure, and “know their numbers”.

“This initiative will help people manage their risk factors earlier and reduce their risk of having heart attacks or strokes,” he said.

Alison McGovern, a health minister, said it was “exactly the type of innovation” she wanted to see across the NHS.

“We’re making it easier for people to spot potential problems earlier and take action to protect their health,” she said.

“Early detection can help prevent serious conditions such as heart attacks and strokes, helping people stay healthier for longer while reducing pressure on NHS services.”

How Does High Cholesterol Raise Heart Risks?

Too much LDL (“bad”) cholesterol in the blood can build up inside artery walls. Over time, these fatty deposits — called plaque or atheroma — can make arteries narrower and restrict blood flow, according to the NHS.

High cholesterol usually causes no symptoms, which is why testing is important. Cholesterol can be reduced through healthier eating and regular exercise and, for people at sufficient risk, medicines such as statins.

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