Many of us believe that we are great drinkers and that alcohol does not affect us as much. People who are able to drink without showing any sign of inebriation are known as social drinkers. In short, they are not addicted to alcohol but will not turn down the opportunity to have a good time! While it may seem like it doesn’t affect you, new studies suggest that it is just an illusion, even if you have high tolerance, alcohol affects your cognitive and motor functions more than you think.

The study reveals the below implications and techniques:

• Researchers used a new MRI technique to precisely measure brain electrical activity.
• By comparing brain scans before and after drinking, scientists identified specific areas affected by alcohol and how much brain activity slowed down.
• Participants were chosen to be regular social drinkers without alcohol addiction, ensuring the study focused on the effects of alcohol alone.
• MRI technology provided reliable data on brain activity changes caused by alcohol consumption.

How does the brain react to alcohol?

Think of it as the foundation for your brain's performance. When brain conductivity is high, information flows smoothly, and that helps your brain in rapid processing and response. On the other hand, low conductivity can hinder cognitive function, leading to slower thinking, impaired memory, and difficulties with coordination.

A study conducted at the Neuroscience Research Australia (NeuRA) and UNSW Science unveiled a startling connection between alcohol consumption and brain conductivity.

What is the connection between alcohol consumption and brain activity?

While many people brush off the effects of alcohol as temporary changes in behaviour, the reality is much more complex. Beyond the obvious impacts on coordination and judgment, alcohol significantly alters brain function. Alcohol dramatically slowed down brain activity, especially in areas responsible for decision-making, planning, and physical coordination. This decline was so significant that it resembled the brain changes seen in normal ageing. This means even one drink could temporarily accelerate the ageing process of your brain.

Alcohol and Brain activity: What does the study Imply?

The implications of this research are far-reaching. It provides compelling evidence that alcohol consumption has a direct and measurable impact on brain function. The discovery that alcohol can significantly reduce brain conductivity opens new avenues for understanding the neurocognitive effects of alcohol abuse and dependence. While you may not feel like alcohol is affecting you and you have a high tolerance, it most definitely changes and affects your decision-making abilities and impulse control.

Furthermore, the MRI technique employed in the study could be a valuable tool for assessing the impact of other substances on the brain and for developing interventions to mitigate alcohol-related brain damage.

Royal Gwent Hospital in Newport, Wales treated 21 patients with unsterilized surgical instruments. The patients were not informed of the error for three weeks. As per a BBC report, the instruments were disinfected but not medically sterilized, which is a typical medical protocol. On February 24, the outlet carried out a breach of protocol, and then on February 25 and 26, the same instruments were used in operations and examinations.

While the error was discovered by hospital staff on February 27, the patients were not informed till March 16.

What Happens When Unsterilized Hospital Instruments Are Used?

Surgical tools that are improperly sterilized could spread bloodborne diseases like HIV and hepatitis. In a statement obtained by the BBC from Aneurin Bevan University Health Board, the organization that manages Royal Gwent Hospital, a spokesperson said the situation is being investigated. The spokesperson also said that they have arranged for "precautionary testing" for all affected patients, and that "the clinical risk of bloodborne virus exposure is extremely low".

"We fully recognize the concern and distress this may cause, and we are truly sorry. The well-being of our patients is our highest priority, and we are taking all necessary actions to understand how this happened and to prevent it from occurring again,” the board's statement continued.

They additionally stated that “this was a very limited incident” and that “there is no wider cause for concern.”

Family Speaks Out After Teen Patient Affected

One of the patients affected is 15-year-old Ieuan, who underwent an orthodontic procedure at Royal Gwent Hospital. His parents said the call from the hospital informing them about the sterilization error came as a shock.

According to the family, the news was difficult to process, especially because their son will now have to undergo a series of medical tests over the next six months. Ieuan later said he initially felt frightened after learning about the possible exposure and is hoping the tests confirm he is safe.

The teenager has already undergone his first blood test at the hospital and is scheduled for additional tests in the coming months before doctors can give him a final all clear.

What Went Wrong During The Procedure

Ieuan had braces fitted on February 25 during a routine orthodontic appointment to address gaps in his teeth following an earlier dental operation.

During the procedure, staff used instruments including pliers used to trim brace wires and a dental mirror. The hospital later confirmed that while the tools had been disinfected, they were not placed in an autoclave, the specialized machine that sterilizes medical equipment using high heat and steam.

Standard protocol requires staff to confirm that sterilization indicators on instrument trays have changed color after the process and to check the sterilization date before use. According to the health board, this verification step was missed due to what it described as human error.

Health officials say investigations are ongoing, and monitoring of affected patients will continue over the coming months.

Indian drug regulator - Central Drugs Standard Control Organisation (CDSCO) found 90 combination medicines that are sold without mandatory central approval. This has raised concerns on regulatory compliance in the country's pharmaceutical supply chain.

CDSCO is the apex drug regulatory body in the country. The authority wrote a letter to all states and union territory drug controllers and asked them to investigate manufacturers and marketers of these fixed-dose combinations (FDCs).

What are FDCS? These are drugs that contain two or more active ingredients in a single formulation. The CDSCO asked them to investigate and submit reports on the action taken at the earliest.

What Made To The Unapproved List Of FDCs?

The annexure attached to the letter showed 90 combination medicines had made it to the market. These contain cough syrups, vitamins, and anti-diabetic pills.

Cough And Cold Medicines

Cough and cold combination medicines have formed the single largest group. At least 14 to 16 entries show combination of ingredients found in everyday pharmacy shelves: dextromethorphan, ambroxol, guaiphenesin, chlorpheniramine, phenylephrine, terbutaline, and menthol in various permutations. Several of these are sold as flavoured syrups for children. Budesonide-levosalbutamol inhalation suspension that is used for asthma and chronic obstructive pulmonary disease, too features in the list.

Nutritional Supplements

The next group is of the vitamins, minerals and other nutritional supplement which has roughly 18 to 20 entries. They include:

• Multivitamin capsules
• Iron-folic acid syrups
• Calcium-vitamin D3-K2 combinations
• Abapentin-methylcobalamin preparation

Antifungal and Dermatological Combinations

This group has accounted for at least 10 entries, which include antifungal creams that could lead to potential misuse and skin damage when sold without prescriptions.

Anti-diabetic Medicines

This has accounted for six entries, and the combination includes:

• Glimepiride paired with metformin or pioglitazone

What Did CDSCO Write To Drug Controllers?

The letter dated 18 March was signed with Drugs Controller General of India (DCGI), Dr Rajeev Singh Raghuvanshi. He described the matter as being "top priority in the interest of public health". The unapproved drugs were detected during a scrutiny of laboratory testing data submitted through SUGAM, which is CDSCO's online portal for drug sample testing, for the year 2025.

“This is to inform you that upon scrutiny of the SUGAM lab testing data for the year 2025, a large no. of drug samples (FDCs) are detected as unapproved and fall under the category of ‘New Drug. No new drug shall be manufactured for sale unless it is approved by the licensing authority."

What Is India's Rule For FDCs?

Under India's New Drugs and Clinical Trial Rules of 2019, any FDC is treated as a new drug and must have the central government's approval before it could be manufactured and sold. The regulator's letter noted that there were presence of unapproved drugs in the supply chain that could pose risks to public health. This also amounts to a violation of the Drugs and Cosmetics Act, 1940.

“The presence of unapproved drugs in the supply chain is a matter of serious concern, posing potential risks to public health and safety. It also indicates non- compliance with the provisions of the Drugs and Cosmetics Act, 1940, and Rules made thereunder," it said.

DCGI urged states and UTs "to examine the unapproved FDCs in generic name as mentioned in the attached annexure". This is done to check whether any approval has been granted by the local office. "Accordingly, please initiate appropriate investigation and regulatory action against the concerned manufacturers, marketers, and other stakeholders, as deemed fit. Kindly ensure strict monitoring and enforcement to prevent the manufacture, sale, and distribution of such unapproved drugs," the letter noted.

Jessie J, 37, was rushed to hospital after a car injury that left her in fears that she broke her neck. She underwent an MRI scan after the incident and kept her fans on loop through her Instagram update.

Currently in China, the singer is there for her No Secrets Tour. She said that she suffered an injury after hitting her head on the roof of the car. The singer had shared a video where she was climbing into the back of the car after her latest concert and said she "didn't mind squashing in the back". The video then cuts to her being in the hospital undergoing an MRI scan after she had suffered a neck injury.

She said, "Yeah, I just can't move my head. I'm alright. I'll just have to take some painkillers and march right through it." She further said, "I thought I'd broken my neck, but I haven't. But I have really hurt my neck and my back."

In her later shots, she was seen trying on her gold jumpsuit while embracing her young son Sky. However, she did not let this injury stop her from performing. Many fans also commented her messages of love and well wishes.

Jessie J Health Update

Previously, the singer took to her Instagram to share her stage-one breast cancer diagnosis, fans everywhere were left both shocked and motivated. The 37-year-old singer-songwriter, announced the news in typical frankness, mixing vulnerability with as she explained the surgery she'd be having after performing at Capital's Summertime Ball at London's Wembley Stadium.

In her heartfelt video message, Jessie shared that she has been “in and out of tests” recently and ultimately received a diagnosis of early breast cancer. “Cancer sucks in any form,” she said, “but I’m holding on to the word early.”

With a nod of dark humor, she added, "It's a very dramatic way to get a boob job," vowing followers, "I will come back with massive boobs and more music." But under the humor lay raw emotion and an earnest appeal for sympathy and understanding. "I need to process it and talk about it," she said. "I need a hug."

Having struggled with a string of serious health problems in the past, including a childhood heart condition, a stroke at age 18, Meniere's disease, and even recently being diagnosed with ADHD and OCD, Jessie J is certainly no newcomer to working through health problems. But this latest installment has introduced her to an even more intimate, more personal view.

By disclosing her diagnosis, Jessie J is part of a rising number of public figures using their influence to make health screening and breast cancer discussions more mainstream. Such openness is particularly important in light of the fact that many young women still unrealistically believe breast cancer is an "older woman's disease."