Many of us believe that we are great drinkers and that alcohol does not affect us as much. People who are able to drink without showing any sign of inebriation are known as social drinkers. In short, they are not addicted to alcohol but will not turn down the opportunity to have a good time! While it may seem like it doesn’t affect you, new studies suggest that it is just an illusion, even if you have high tolerance, alcohol affects your cognitive and motor functions more than you think.

The study reveals the below implications and techniques:

• Researchers used a new MRI technique to precisely measure brain electrical activity.
• By comparing brain scans before and after drinking, scientists identified specific areas affected by alcohol and how much brain activity slowed down.
• Participants were chosen to be regular social drinkers without alcohol addiction, ensuring the study focused on the effects of alcohol alone.
• MRI technology provided reliable data on brain activity changes caused by alcohol consumption.

How does the brain react to alcohol?

Think of it as the foundation for your brain's performance. When brain conductivity is high, information flows smoothly, and that helps your brain in rapid processing and response. On the other hand, low conductivity can hinder cognitive function, leading to slower thinking, impaired memory, and difficulties with coordination.

A study conducted at the Neuroscience Research Australia (NeuRA) and UNSW Science unveiled a startling connection between alcohol consumption and brain conductivity.

What is the connection between alcohol consumption and brain activity?

While many people brush off the effects of alcohol as temporary changes in behaviour, the reality is much more complex. Beyond the obvious impacts on coordination and judgment, alcohol significantly alters brain function. Alcohol dramatically slowed down brain activity, especially in areas responsible for decision-making, planning, and physical coordination. This decline was so significant that it resembled the brain changes seen in normal ageing. This means even one drink could temporarily accelerate the ageing process of your brain.

Alcohol and Brain activity: What does the study Imply?

The implications of this research are far-reaching. It provides compelling evidence that alcohol consumption has a direct and measurable impact on brain function. The discovery that alcohol can significantly reduce brain conductivity opens new avenues for understanding the neurocognitive effects of alcohol abuse and dependence. While you may not feel like alcohol is affecting you and you have a high tolerance, it most definitely changes and affects your decision-making abilities and impulse control.

Furthermore, the MRI technique employed in the study could be a valuable tool for assessing the impact of other substances on the brain and for developing interventions to mitigate alcohol-related brain damage.

Epstein Files photos show someone holding a bottle of medication, which has come up in the latest batch of photos released on December 18 by House Oversight Democrats, as part of the 68 photos from Jeffrey Epstein's estate. On the bottle is a label with the word "Phenazopyridine". Why was this medicine there? What does it do?

What Is Phenazopyridine And Why We Think It Was Found At Epstein's House

Phenazopyridine is commonly used to reduce symptoms like urinary pain, burning, or feeling the urgency to pee. It is also used to treat bladder infections or urinary tract infection. WebMD says that it could also be used to help relieve symptoms from other causes like surgery or another procedure.

The Epstein files as we know are a body of documents that detail the criminal activities of American financier and convicted child sec offender, previously it had been reported that he allegedly paid doctors to medicate underage abuse victims. He would get doctors to prescribed anti-anxiety or anti-depressants medications, birth control pills, and also got the victims screened for sexually transmitted diseases, as HuffPost reports.

This is why we think he may have used this common UTI medication: Urinary Tract Infections or UTI are very common after sexual activities, especially for women. It is also because intercourse could push bacteria like E.coli from the genital area into the urethra, this could lead to infection. Since the urethra is shorter in women, it makes it easier for bacteria to reach the bladder. Furthermore, Phenazopyridine is also an over-the-counter, non-antibiotic method to prevent or reduce post-coital UTI frequency and could also eliminate the need for antibiotics.

Epstein Used Medicine To Drug His Victims

Previous reports too show how Epstein had used medicines to drug his victims. Virginia Giuffre told the Miami Herald that she was only 16 when she was recruited to give Epstein "massages". She revealed that she was prescribed Xanax, when she lived and traveled with Epstein for several years.

Another accuser Sarah Ransome said that when she told a doctor that she was sexually abused by Epstein, she was prescribed lithium.

What Do These Medicines Do To You?

Alprazolam, commonly sold under the brand name Xanax is used for anxiety and panic disorder. WebMD says that it produces a calming effect on the brain and helps reduce anxiety, while promoting relaxation. Reports show that he got a doctor prescribe these drugs so he would control the young women, and sedate them and induce amnesia of the abuse. Experts have noted that it can be used as a "date rape" or "grooming drug" because it makes users "zombie-like" or "dazed".

Lithium on the other hand, notes the National Health Service or NHS, UK, slows down the thinking and makes the people feel a bit "numb". Other side effects of lithium also include feeling tired or sleepy, along with lightheadedness, drowsiness, confusion, blackout, and difficulty speaking. This could also be used to control young victims.

Note: No reports have confirmed the use of Phenazopyridine found in Epstein estate as of now. This piece will be updated as and when there is any other information.

Super flu virus, or the new strain of H3N2 influenza is spreading and has affected a growing number of Canadians, reported the Global News. It is "increasing rapidly" around the country, warn experts. Health Canada confirmed that all regions of the country is affected by the growing influenza activity.

In the first week of December, Canada saw 6,799 cases of the flu with 91 outbreaks across the country. The number of positive tests also rose by 20.2 per cent as compared to the week before. Hospitalization numbers too have gone up with 3.6 hospitalization per 100,000 population, reported the Global News.

The strain causing a havoc in public health in Canada is the influenza A (H3N2) strain, which includes a subvariant A (H3N2) subclade K, noted the World Health Organization (WHO).

Who are hit the hardest? According to Health Canada's report, children are among those being hit hard, and most infections are detected in people under 19.

What Is The Super flu doing in Canada?

After the death of three children in Ottawa, between age five and nine, the health officials have urged anyone over the age of six months to get vaccinated. This means, the parents must step in now. In November, the Children's Hospital of Eastern Ontario, colloquially known as CHEO, also witnessed eight times more children tested positive for influenza as compared to the data of the same month from previous year. Hospitalized too doubled with children affected by flu.

Also Read: Is 2025 The Year Of Flu?

CHEO in a statement said, "The flu is more than a bad cold."

“Children under five are at a higher risk of severe illness from influenza because they have smaller airways, and their immune systems are still developing. Even healthy kids can become seriously ill, and flu spreads quickly in schools and child-care settings.”

Hospitals in Alberta too are seeing a flood of flu patients, this has jumped up to 70 per cent in a week. Dr Fahad Razak, internal medicine physician and professor at the University of Toronto told the Global News that 1 in 5 of all tests are being done are positive. "So that suggests we are right in the midst of that surge. The numbers could go higher."

Thanks to the holiday season and with increased travel, this will impact the surge in numbers, Dr Isaac Bogoch, Infectious disease specialist at Toronto General Hospital told the outlet, "It’s probably going to end up being a more severe and a more significant flu season compared to the average flu season."

Why Is This New Strain Hitting Hard?

Doctors explain that subclade K enhances the ability of the virus to slip through our immune protection. However, it does not mean that vaccination offers no protection against the flu. In fact, experts and doctors have been emphasizing the need to get yourself vaccinated to help you protect from the worst effects of the virus.

“If you look at deaths and severe illness with flu, the vast majority both in adults and in children are unvaccinated,” Razak said.

“Yes, you may get sick, even if you are vaccinated, it’s that the severity, the chance that you’re going to end up in hospital and worst-case scenario in the ICU or die does seem to be significantly protected against by being vaccinated.”

Health Canada too noted that vaccination can prevent anyone infected with influenza from developing any further complications.

Are Other Countries Impacted?

Apart from Canada, the UK and the US are also impacted by the superflu or the subclade K. In the UK the National Health Service (NHS) declared that the country is currently facing "worst case scenario" for December as flu hospitalization has surged by more than half in just one week. NHS in a statement last week said, on an average 2,660 patients were being hospitalized per day with flu last week. This is the higher ever for this time of the year with the surge being up by 55 per cent compared with the week before.

In the US, the Centers for Disease Control and Prevention (CDC) noted that infections are growing in 43 states.

Depo Provera: The Food and Drug Administration approved a label change on Friday for Pfizer’s birth control injection, Depo-Provera, alerting patients to the risk of meningioma, a tumor that develops in the lining of the brain.

Pfizer is currently facing a lawsuit from over 1,000 women who allege that the company knew about the risk but failed to warn users.

How Depo-Provera Works

Depo-Provera is administered as a progestin injection every three months. The lawsuit highlights studies dating back to 1983 linking progesterone with meningioma, claiming that Pfizer had an “unassignable duty to investigate” and should have examined the potential risks of Depo-Provera much earlier. (Progestin is a synthetic form of progesterone.)

According to the Centers for Disease Control and Prevention, roughly one in four sexually active women in the U.S. has used Depo-Provera, with Black women using it at nearly twice the national rate.

Depo Provera: Understanding Meningiomas

Meningiomas are generally non-cancerous, meaning they do not spread to other areas of the body. However, depending on their size and location, they can still be dangerous. In the U.S., about 39,000 meningiomas are diagnosed annually, though the overall risk remains small, as per CDC.

Depo Provera: Pfizer’s Response and FDA Review

Earlier this year, Pfizer requested a judge dismiss the lawsuit, stating that it became aware of the meningioma risks linked to Depo-Provera in 2023. In February 2024, the company applied to the FDA to add a warning to the injection’s label, also requesting warnings for two lower-dose pills containing medroxyprogesterone acetate (MPA), the active ingredient in the shot, as per NBC News.

The FDA denied the request for the pills, explaining that “the findings of the available observational studies alone do not support the addition of a warning on Meningioma risk to medroxyprogesterone acetate (MPA)-containing products.”

Pfizer then amended and resubmitted the application in June 2025. In response, the FDA approved a label change this month for two injection versions — Depo-Provera CI and Depo-Subq Provera 104.

“We acknowledge receipt of your amendment dated June 12, 2025,” the FDA letter to Pfizer said. The approval “provides for the addition of information related to Meningioma risk” on the product label.

Depo Provera: Pfizer’s Statement

A Pfizer spokesperson told NBC News that “the label update reflects a recent decision by the FDA to approve the warning, which the agency had earlier denied.”

“Pfizer stands behind the safety and efficacy of Depo-Provera, which has been used by millions of women worldwide and remains an important treatment option for women seeking to manage their reproductive health,” the statement added.

Lawyers representing the women suing Pfizer said: “For years, Pfizer misled doctors, patients, and the FDA about Depo-Provera’s link to meningiomas, resulting in needless suffering for thousands of women who developed these serious brain tumors. … We applaud the FDA in finally requiring this label change to better inform and protect women.” The FDA did not immediately respond to requests for comment. Elsewhere, warnings about meningioma have already been added to Depo-Provera’s label.

In 2024, the European Medicines Agency listed meningioma as a “possible side effect” for drugs with high doses of MPA. That same year, Canada updated the drug’s label to include meningioma under “warnings and precautions,” noting that meningiomas have been reported following long-term use of progestins, including MPA.

As per NBC News, in January, South Africa’s regulatory agency recommended updating the MPA drug label to include meningioma risk as well. The judge has not yet issued a ruling in the ongoing lawsuit against Pfizer in the United States.