Do You Think You Have High Alcohol Tolerance? Here’s How Liquor Impacts Your Brain Activity

Updated Aug 9, 2024 | 03:00 PM IST

SummaryA recent research sheds light on social drinkers and how even moderate alcohol consumption can impact brain activity, challenging the notion that occasional drinking is harmless.
Liquor Impacting Brain Activity (Credit-Freepik)

Liquor Impacting Brain Activity (Credit-Freepik)

Many of us believe that we are great drinkers and that alcohol does not affect us as much. People who are able to drink without showing any sign of inebriation are known as social drinkers. In short, they are not addicted to alcohol but will not turn down the opportunity to have a good time! While it may seem like it doesn’t affect you, new studies suggest that it is just an illusion, even if you have high tolerance, alcohol affects your cognitive and motor functions more than you think.

The study reveals the below implications and techniques:

  • Researchers used a new MRI technique to precisely measure brain electrical activity.
  • By comparing brain scans before and after drinking, scientists identified specific areas affected by alcohol and how much brain activity slowed down.
  • Participants were chosen to be regular social drinkers without alcohol addiction, ensuring the study focused on the effects of alcohol alone.
  • MRI technology provided reliable data on brain activity changes caused by alcohol consumption.

How does the brain react to alcohol?

The human brain is a complex network of billions of neurons that communicate through electrical impulses. Brain conductivity refers to the efficiency with which these electrical signals travel through brain tissue. It's akin to the speed and clarity of a digital signal through a wire. In layman terms, your brain must function in its peak condition as it is essential for various cognitive processes, including memory, attention, decision-making, and motor control.

Think of it as the foundation for your brain's performance. When brain conductivity is high, information flows smoothly, and that helps your brain in rapid processing and response. On the other hand, low conductivity can hinder cognitive function, leading to slower thinking, impaired memory, and difficulties with coordination.

A study conducted at the Neuroscience Research Australia (NeuRA) and UNSW Science unveiled a startling connection between alcohol consumption and brain conductivity.

What is the connection between alcohol consumption and brain activity?

While many people brush off the effects of alcohol as temporary changes in behaviour, the reality is much more complex. Beyond the obvious impacts on coordination and judgment, alcohol significantly alters brain function. Alcohol dramatically slowed down brain activity, especially in areas responsible for decision-making, planning, and physical coordination. This decline was so significant that it resembled the brain changes seen in normal ageing. This means even one drink could temporarily accelerate the ageing process of your brain.

Alcohol and Brain activity: What does the study Imply?

The implications of this research are far-reaching. It provides compelling evidence that alcohol consumption has a direct and measurable impact on brain function. The discovery that alcohol can significantly reduce brain conductivity opens new avenues for understanding the neurocognitive effects of alcohol abuse and dependence. While you may not feel like alcohol is affecting you and you have a high tolerance, it most definitely changes and affects your decision-making abilities and impulse control.

Furthermore, the MRI technique employed in the study could be a valuable tool for assessing the impact of other substances on the brain and for developing interventions to mitigate alcohol-related brain damage.

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Hepatitis B Infections Could Rise 83% If US Changes Newborn Vaccine Policy: Study

Updated Oct 21, 2026 | 07:04 AM IST

SummaryA recent study published in the 'Annals of Internal Medicine' projected that hepatitis B infections could increase by at least 83% if the decision to vaccinate an infant is left to parents and healthcare providers.
Hepatitis B Infections Could Rise 83% If US Changes Newborn Vaccine Policy: Study

Credit: iStock

Chronic hepatitis B infections among children and young adults in the United States could rise by 83% if the country moves away from routinely recommending vaccination at birth for all newborns, according to a new study titled Projected Effect of 2026 Federal Changes to the Childhood Immunization Schedule on Chronic Hepatitis B Virus Infections in the United States, published in Annals of Internal Medicine recently.

Researchers from Massachusetts General Hospital and Harvard Medical School analysed outcomes for a birth cohort of 3.6 million infants over their first 20 years.

The study examined the impact of changes to US hepatitis B vaccine recommendations for babies born to mothers who test negative for the virus.

Under the revised approach, parents and healthcare providers decide together whether and when to begin vaccination. The findings suggest that this could leave more children vulnerable to infection, increasing the cases of chronic hepatitis B.

What Did The Study Find?

The model compared universal vaccination at birth with two alternatives. The first is delaying the first dose until at least two months of age, and the second is leaving the decision to parents and healthcare providers.

Researchers estimated that delaying vaccination could increase chronic hepatitis B infections acquired by age 20 by 19%. Under the second option, the estimated increase was 83%.

The model estimated 255 chronic infections under universal birth-dose vaccination, compared to 303 if vaccination was delayed and 467 under shared decision-making.

The number of people who remained at high risk to hepatitis B at age 20 was also projected to increase. Under universal vaccination at birth, around 232,000 people in the cohort would remain at risk. This rose to 474,000 with delayed vaccination and approximately 1.8 million under shared decision-making.

Study's corresponding author Amir Mohareb said, “These findings show why policy makers should re-implement recommendations for universal hepatitis B vaccination at birth.”

Importance Of Hepatitis B Birth Dose

Hepatitis B is a viral infection that affects the liver and spreads through infected blood and certain bodily fluids, including during childbirth. Infection acquired during infancy is likely to become chronic, leading to cirrhosis, liver failure or liver cancer in the future.

The universal hepatitis B birth-dose recommendation was introduced in the US in 1991. The first dose provides early protection, including when maternal infection is missed or a child's exposure risk is not recognised.

In December 2025, the US Advisory Committee on Immunization Practices recommended replacing universal vaccination at birth with shared decision-making for infants whose mothers test negative.

The Centers for Disease Control and Prevention adopted this approach in January 2026. Babies born to mothers who test positive or whose infection status is unknown continue to be recommended to receive the birth dose promptly, along with hepatitis B immune globulin when indicated.

The researchers said the findings suggest that reducing routine vaccination at birth could increase chronic infections and leave more people vulnerable as they enter adulthood. The 83% figure is a modelled projection, not actual increase in infections. The results depend on assumptions about vaccine uptake and other factors.

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G155E H1N1 Mutation In US Raises Concerns: Can This Year’s Flu Shot Still Protect You?

Updated Oct 21, 2026 | 12:00 AM IST

SummaryExperts said two of this season’s three flu vaccine components appear well matched to circulating strains and recommended early vaccination. The American Medical Association recommends annual flu shots for everyone aged six months and older.
G155E H1N1 Mutation In US Raises Concerns: Can This Year’s Flu Shot Still Protect You?

Credit: iStock

Scientists have identified a new H1N1 mutation, G155E, in US flu samples, raising questions about immunity and vaccine protection as the flu season begins early.

Early laboratory findings suggest the mutation may make some H1N1 strains harder for existing antibodies to recognize. However, the vaccine’s effectiveness specifically against G155E remains uncertain, and there is no evidence yet that the mutation makes the flu shot ineffective.

H1N1 Becomes The Dominant Flu Strain In US

According to the US Centers for Disease Control and Prevention’s (CDC) October 2 report, 53 of 55 influenza A samples undergoing subtyping were H1N1, while two were H3N2. No influenza B viruses were reported in this group.

Researchers at the University of Washington identified G155E in 13 of 17 sequenced H1N1 samples collected from hospitals and clinics in the Seattle area.

Could G155E Affect Flu Shot Effectiveness?

Also read: Flu 2026: Symptoms To Watch For As New Season Begins

The 2026-2027 flu vaccines approved by the US Food and Drug Administration target H1N1, H3N2 and an influenza B virus.

Dr. Jennifer Duchon, a pediatric infectious disease expert at Mount Sinai Children’s Hospital, told Reuters that younger people may have had limited exposure to this year’s H1N1 strain.

“What people are a bit worried about is that the H1N1 strain this year hasn't been seen by a lot of younger folk, so it may be more severe in them,” she said.

However, this concern does not establish that G155E causes more severe disease. Flu vaccine effectiveness varies by season and depends partly on how well vaccine strains match circulating viruses.

Scott Hensley, a microbiologist at the University of Pennsylvania, told Reuters that two of this season’s three vaccine components appear well matched to circulating strains. He also recommended getting vaccinated early.

The American Medical Association also recommends annual flu vaccination for people aged six months and older, unless they have a medical reason not to receive it.

G155E: Who Could Be More Vulnerable?

Read More: Flu Vaccine: Why October Is A Good Time To Get Your Family Vaccinated

Antibody studies suggest that people exposed to influenza last year may have antibodies that recognize the new mutation less effectively, particularly among teenagers and young adults.

Researchers at the Fred Hutchinson Cancer Center, including virologist Jesse Bloom, examined antibody responses to influenza A strains carrying mutations such as G155E.

In a preprint posted on bioRxiv, researchers tested antibodies from 260 people in Australia and the US against 148 influenza A strains that circulated through mid-2026. Some G155E-carrying strains were less readily recognized by antibodies, particularly those from younger people.

The researchers suggested that limited previous exposure to similar H1N1 variants could help explain this difference. However, laboratory findings alone cannot establish how likely people are to become infected or develop severe illness.

Should You Worry About G155E?

The mutation warrants monitoring, but current evidence does not establish that it makes the flu shot ineffective. How well this season’s vaccine protects against G155E remains uncertain.

Annual flu vaccination remains an important preventive measure, particularly for people at higher risk of complications. Regular hand hygiene and other basic precautions can also help reduce the spread of infections.

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Christina Applegate Reveals Multiple Sclerosis Misdiagnosis: Why The Disease Is Hard To Diagnose

Updated Oct 20, 2026 | 10:00 PM IST

SummaryDespite being told she did not have MS, Christina Applegate said her debilitating symptoms persist. She still relies on a wheelchair to visit her doctor and struggles to walk even short distances. She also expressed confusion and distress over not knowing what is causing her ongoing symptoms.
Christina Applegate Reveals Multiple Sclerosis Misdiagnosis: Why The Disease Is Hard To Diagnose commons.wikimedia

Credit: Wikimedia Commons

Emmy-winning American actor Christina Applegate has in a shocking news revealed that she does not have multiple sclerosis (MS), despite continuing to experience debilitating symptoms since her 2021 diagnosis.

Applegate, 54, shared the news in an episode of her podcast MeSsy, co-hosted with fellow actor Jamie-Lynn Sigler and posted to YouTube on Tuesday.

“I’m back at square one – that I don’t know what’s going on with me,” she said through tears.

Applegate had gradually withdrawn from public life after her MS diagnosis in 2021, as she navigated the physical and emotional toll of the condition.

She has also become an advocate for MS awareness and chronicled her struggles in an emotional memoir published in March.

Christina Applegate Recalls Learning About Her Misdiagnosis

Also read: Why Multiple Sclerosis Increases Emotional Burden Among Women

Applegate recalled a visit to her doctor when she was told she did not have MS.

“She came into my room and said, ‘Congratulations, you don’t have MS,’” Applegate recalled through tears. “I was, like, not happy at all. Everybody else was so happy.”

Despite the news, Applegate said her symptoms have not improved.

“I haven’t gotten better. I still have to use wheelchairs when I go to the doctor’s office. I can’t walk from the car to the room. I’m still in this. Nothing magical happened when she said, ‘You don’t have MS.’ Nothing magical happened.”

Applegate also described feeling confused about her condition and the uncertainty surrounding her symptoms.

“It’s weird because I feel like I let everybody down. It’s this weird feeling of like I became this, you and I, the poster children for MS. Everything that I was doing, I had a fucking reason as to why my day sucked every day.

“And now I don’t have a reason. It’s very unnerving and it’s really confusing for me.”

What Is Multiple Sclerosis?

Read More: Selena Gomez Says Vaping Changed Her Voice: How E-Cigarettes Affect Vocal Cords

According to the National Institute of Neurological Disorders and Stroke, multiple sclerosis is a chronic neurological condition that affects the central nervous system, including the brain, spinal cord and optic nerves.

MS is also an immune-mediated disease in which the immune system attacks myelin, the protective sheath surrounding nerve fibers. Damage to myelin can disrupt nerve signals, causing symptoms that vary from person to person.

These may include muscle weakness, fatigue, numbness, coordination problems, vision changes and memory difficulties.

MS is commonly diagnosed between the ages of 20 and 40, although it can develop earlier or later. There is no cure, but treatments can help manage symptoms and slow disease progression. Some people experience relapses with periods of improvement, while others develop progressively worsening disability.

Why Is Multiple Sclerosis Hard To Diagnose?

Dr. Marwa Kaisey, an associate professor in the Department of Neurology at Cedars-Sinai Medical Center, joined Applegate and Sigler on the podcast to discuss MS misdiagnosis.

Kaisey said misdiagnoses are “fairly common” because there is no single test that can definitively confirm or rule out MS.

“We don’t have one single test for MS. It’s not like we have something like a pregnancy test that says, ‘Yes. You have it.’ ‘No. You don’t.’ It’s a list of criteria.”

Kaisey said nearly 20% of people diagnosed with MS may not actually have the disease, People.com reported.

“Almost one in five of these people who’d been told they had MS, some for decades, didn’t actually have it. And a majority of them were on medication to treat their MS,” she said.

MS diagnosis typically involves assessing symptoms, a neurological examination, magnetic resonance imaging (MRI) and, when appropriate, additional tests to rule out other conditions.

Because several disorders can cause similar symptoms, clinicians must evaluate the findings against established diagnostic criteria.

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