The Union Health Ministry implemented a ban on 156 "irrational" FDC medicines, effective immediately. These medicines, including widely used antibiotics, painkillers, and multivitamins, were commonly used to treat fever, cough, and infections. The ban was imposed due to the associated health risks and lack of therapeutic justification for the ingredients in these FDCs.

What are FDC medicines?

FDCs or fixed-dosed combinations, also known as "cocktail drugs," are medications that combine multiple drugs in a single pill. They are designed to treat multiple symptoms or conditions simultaneously. While they offer convenience, they can pose significant risks. These risks include the possibility of overdose, adverse interactions between the drugs, and the development of antibiotic resistance. Additionally, many FDC medicines lack sufficient scientific evidence to support their safety and efficacy.

Expert opinions on FDC medicines

Experts have raised concerns about the use of FDC medicines. They believe that many of these combinations lack sufficient scientific evidence to support their safety and effectiveness. Additionally, the combination of multiple drugs in a single pill can increase the risk of adverse side effects and interactions with other medications.

Experts have also found that FDC medicines may not be as effective as individual drugs in treating certain conditions. It is important to note that safer and more effective alternatives are available for most of the medical conditions that FDC medicines were used to treat. One particular concern is the inclusion of antibiotics in some FDCs. Overuse of antibiotics can contribute to the development of antibiotic resistance, a major public health threat.

The risks of FDC medicines

The use of FDC medicines can lead to adverse effects, including serious ones. Additionally, safer alternatives, tested in clinical trials, are available to treat the same medical conditions. Experts recommend prescribing drugs individually based on a patient's clinical symptoms rather than combining them in FDCs.

The ban on irrational FDC medicines by the Union Health Ministry can be seen as a positive step towards promoting rational drug use and protecting public health. The goal is to eliminate unnecessary and potentially harmful drug combinations. This is a step forward in reducing the risks associated with medication and ensure safer and more effective treatment options for patients.

BBC presenter Lauren Laverne has revealed that she has been diagnosed with smoldering myeloma — a blood and bone marrow disorder that currently has no cure.

The chronic condition was discovered by her doctor nearly two years after Laverne recovered from cancer in August 2024. Laverne has not publicly disclosed the exact type of cancer she was treated for.

Lauren Laverne Reveals 'Chronic Condition'

Taking to Instagram, the 48-year-old TV presenter shared her health update, telling followers that she has been diagnosed with a "chronic condition."

"I’ve been diagnosed with something called smoldering myeloma (yes, that is a weird name and no, I’d never heard of it either)," she wrote. "It’s an asymptomatic blood and bone marrow disorder that in some people can develop into blood cancer."

Stating that her risk "is pretty low," Laverne explained that she does not need treatment at the moment. However, she noted that there is currently no cure and that her immune system is "a bit compromised."

She also clarified that the diagnosis "has nothing to do with my previous illness or my recent surgery, it’s just one of those things."

Also read: Cancer Kills Over 26,000 Daily; Cases to Hit 35 Million by 2050, Says WHO Report

Regular Monitoring Ahead

Because of the diagnosis, Laverne said she will be closely monitored with blood tests, MRIs, and bone marrow biopsies, which she joked she has "recently discovered are even less fun than they sound."

She revealed that the condition was identified after her GP noticed she had "persistently low iron levels."

"I've had some difficult experiences in the last eight years, but I have learned more from them than some people do in a lifetime and that is helping me right now. I am so grateful for that," she said.

Laverne also thanked her family, friends, doctors, consultants, nurses, and her team at BBC Radio 6 Music. Many of her fellow TV and radio personalities shared messages of support following her announcement.

What Is Smoldering Myeloma?

According to Blood Cancer UK, "Smoldering myeloma is the name given to myeloma that has no symptoms or signs of damage to your organs."

Myeloma is a type of blood cancer that affects plasma cells in the bone marrow. Smoldering myeloma is an inactive, early form of the disease that does not cause symptoms or organ damage.

The charity says that people with smoldering myeloma usually do not need treatment right away. Instead, they undergo regular checkups so doctors can monitor whether the condition is progressing to active myeloma.

Read More: Attention Brits! UK Warns Travelers About Deadly Methanol Poisoning Abroad

According to the International Myeloma Foundation, smoldering multiple myeloma (SMM) is an asymptomatic precursor stage of multiple myeloma (MM). While both conditions involve abnormal plasma cells, people with SMM have no symptoms or end-organ damage and are typically monitored rather than treated.

The disease generally progresses through precursor stages:

• Monoclonal gammopathy of undetermined significance (MGUS): The earliest stage before symptoms develop. MGUS is a benign precursor, and many people with MGUS never develop active myeloma.
• Smoldering multiple myeloma (SMM): In some people, MGUS progresses to SMM, which remains asymptomatic. Over time, SMM can progress to active multiple myeloma, although the rate of progression varies from person to person.

How Is Smoldering Myeloma Managed?

People with smoldering myeloma are generally managed through active surveillance, with regular blood tests, imaging scans, and other monitoring to detect any signs that the disease is becoming active. Active monitoring is considered a safe approach for most patients.

Doctors may recommend treatment in certain situations, including:

• If tests show a very high risk of progression to active myeloma.
• If there are no symptoms but evidence, or a high risk, of damage to organs such as the bones or kidneys.
• As part of a clinical trial.

Healthcare in India is no longer a privilege but is steadily becoming a right, said Prime Minister Narendra Modi today while highlighting the government's efforts to expand affordable medical care, strengthen health infrastructure and improve access to treatment across the country.

Speaking at the foundation stone laying ceremony and launching development projects worth over ₹4,700 crore in Chandigarh, spanning healthcare, education and road infrastructure, PM Modi stated that India's healthcare journey has undergone a transformational change over the past 12 years.

The Prime Minister said lower and middle-income families have benefited the most from the country's healthcare transformation.

"Health services in India are no longer a privilege; they are becoming an absolute right," PM Modi said.

PGIMER Expansion To Boost Healthcare Access

Also read: Fourth COVID Death Reported in Andhra Pradesh: Experts Recommend Boosters For High-Risk Groups

In Chandigarh, the Prime Minister announced the expansion of healthcare facilities at the Postgraduate Institute of Medical Education and Research (PGIMER), including a new Neuroscience Centre, a Mother and Child Centre, and a Critical Care Hospital Block, saying the projects will provide better treatment facilities to millions of people.

He also announced the approval of a new MBBS college at PGIMER, saying the expansion of medical colleges and postgraduate seats will help address the shortage of doctors while creating more opportunities for aspiring medical students.

Healthcare Infrastructure Expanded Over The Past Decade

Highlighting the government's investments in healthcare, Modi said India has approved 15 new AIIMS since 2014, established hundreds of new medical colleges and expanded specialty hospitals across the country.

"Since 2014, fifteen new AIIMS have been approved, hundreds of new medical colleges have been established across the country, and specialized hospitals for the treatment of serious diseases such as cancer have been strengthened."

He added that strengthening primary healthcare remains a key priority under the Ayushman Bharat Health Infrastructure Mission.

The Prime Minister said that under the mission, critical care blocks, integrated public health laboratories and public health units have been established across the country. He added that over 1.75 lakh Ayushman Arogya Mandirs are now operational across rural, urban and tribal areas, providing comprehensive primary healthcare services, including twelve healthcare service packages.

He noted that crores of citizens have been screened for hypertension, diabetes and other non-communicable diseases through these centers.

Digital Health and Maternal Care Improvements

Read More: Novo Nordisk's GLP-1 Drug Wegovy Approved for Fatty Liver Disease in India

The Prime Minister highlighted the growing role of digital healthcare, noting that the e-Sanjeevani telemedicine platform has facilitated more than 48 crore consultations, enabling patients in remote areas to access specialist care without travelling long distances.

PM Modi said the healthcare improvements have contributed to better maternal and child health outcomes, with more than 90% of deliveries now taking place in healthcare institutions. He added that maternal mortality has declined by 86%, while infant mortality has also fallen significantly.

The Prime Minister also underlined the government's emphasis on preventive healthcare through initiatives such as the Poshan Abhiyan, Mission Indradhanush, yoga promotion, HPV vaccination and the U-WIN platform.

Focus On Tuberculosis Control

PM Modi reaffirmed the Government's commitment to eliminating tuberculosis, stating that the TB Mukt Bharat Abhiyan has strengthened awareness, screening and treatment.

He noted that TB treatment coverage in the country has now crossed 90% and, citing a recent World Health Organization (WHO) report, said India has recorded a 21% decline in tuberculosis cases over the past decade.

India Emerging As A Global Healthcare Destination

Recalling India's response during the COVID-19 pandemic, Modi said the country has evolved from a nation once perceived as dependent on external assistance to a global destination for advanced medical treatment.

He attributed the transformation to sustained investments in healthcare infrastructure and policies aimed at making quality treatment affordable and accessible.

Modi said "India must continue investing in modern healthcare infrastructure and emerging technologies as part of its vision of becoming a developed nation".

India's southern state of Andhra Pradesh has reported four COVID-19 deaths amid a rise in infections, prompting experts to reiterate the importance of booster vaccination for older adults and people at high risk of severe disease.

While sporadic COVID-19 cases have continued to be reported across the country, fatalities have remained relatively uncommon. Health experts say the current situation does not resemble previous pandemic waves, but immunity from earlier vaccinations has waned, making booster doses important for vulnerable groups.

Andhra Pradesh Reports Four COVID Deaths

In an official statement, Andhra Pradesh Health Commissioner G. Veerapandian said that 12 people tested positive for COVID-19 across the state between June 26 and July 16. Of these, four patients with multiple comorbidities died.

The deceased had underlying conditions including hypertension, diabetes, kidney disease, and other serious illnesses.

Although cases have increased in a few states and cities, hospitals are not experiencing the overwhelming admissions, oxygen shortages, or healthcare burden seen during earlier waves.

Also read: Omicron Sub-Lineages Likely Behind COVID Surge In India: Why Deaths Are Occurring

Who Is Most at Risk?

Experts say that while most current infections are mild, severe illness remains more likely in:

• Older adults

• Pregnant women

• People with diabetes

• Individuals with heart disease

• Those with chronic lung or kidney disease

• Cancer patients

• People with weakened immune systems

Experts Advise Boosters For Vulnerable Groups

Read More: COVID Spikes In India: Experts Allay Fears, Stress Vaccination And Masks

Speaking to HealthandMe, Dr. Atul Kakar, Chairperson, Internal Medicine, Sir Ganga Ram Hospital, said booster doses remain advisable for people at highest risk.

"COVID vaccines are now again recommended, especially for the elderly population, particularly those of advanced age or who are immunocompromised. It is a voluntary vaccine that is indicated because immunity from earlier vaccinations has declined."

Dr. Manjeeta Nath Das, Associate Director, Internal Medicine, PB Health, said COVID-19 cases are rising in small pockets, particularly in South India, while immunity from previous vaccination has gradually waned.

"COVID is rising in India, especially in small pockets in South India. So we should all get re-vaccinated. It has been several years since the pandemic, and immunity from previous vaccinations has waned," Das told HealthandMe.

She recommended booster doses for:

• Adults aged 65 years and above

• Immunocompromised children older than six months

• People with diabetes, hypertension, or asthma

• Patients undergoing chemotherapy

• Individuals taking steroids or other immunosuppressive medicines

• Adults with immunocompromising conditions

• Caregivers and healthcare workers caring for vulnerable patients

She also said eligible people may consider an annual COVID-19 booster as immunity declines over time.

Dr. Kakar added that people with weakened immunity, immunodeficiency, advanced age, and pregnant women are among those who would benefit most from a booster.

Heterologous Boosters May Be An Option

Dr. Neha Rastogi, Senior Consultant, Infectious Diseases, Fortis Memorial Research Institute, Gurugram, said booster vaccination should focus on those at the highest risk rather than the general population.

"The focus has shifted from broad herd immunity to priority boosters for the elderly and high-risk groups such as cancer patients, people on dialysis, those with uncontrolled diabetes, patients on steroids, and immunosuppressed individuals."

She told HealthandMe that people who have previously been vaccinated may also consider a heterologous booster—receiving a different COVID-19 vaccine from the one used for their earlier doses—where appropriate and based on medical advice.