The Union Health Ministry implemented a ban on 156 "irrational" FDC medicines, effective immediately. These medicines, including widely used antibiotics, painkillers, and multivitamins, were commonly used to treat fever, cough, and infections. The ban was imposed due to the associated health risks and lack of therapeutic justification for the ingredients in these FDCs.

What are FDC medicines?

FDCs or fixed-dosed combinations, also known as "cocktail drugs," are medications that combine multiple drugs in a single pill. They are designed to treat multiple symptoms or conditions simultaneously. While they offer convenience, they can pose significant risks. These risks include the possibility of overdose, adverse interactions between the drugs, and the development of antibiotic resistance. Additionally, many FDC medicines lack sufficient scientific evidence to support their safety and efficacy.

Expert opinions on FDC medicines

Experts have raised concerns about the use of FDC medicines. They believe that many of these combinations lack sufficient scientific evidence to support their safety and effectiveness. Additionally, the combination of multiple drugs in a single pill can increase the risk of adverse side effects and interactions with other medications.

Experts have also found that FDC medicines may not be as effective as individual drugs in treating certain conditions. It is important to note that safer and more effective alternatives are available for most of the medical conditions that FDC medicines were used to treat. One particular concern is the inclusion of antibiotics in some FDCs. Overuse of antibiotics can contribute to the development of antibiotic resistance, a major public health threat.

The risks of FDC medicines

The use of FDC medicines can lead to adverse effects, including serious ones. Additionally, safer alternatives, tested in clinical trials, are available to treat the same medical conditions. Experts recommend prescribing drugs individually based on a patient's clinical symptoms rather than combining them in FDCs.

The ban on irrational FDC medicines by the Union Health Ministry can be seen as a positive step towards promoting rational drug use and protecting public health. The goal is to eliminate unnecessary and potentially harmful drug combinations. This is a step forward in reducing the risks associated with medication and ensure safer and more effective treatment options for patients.

A team of UK scientists has identified 23 unique mutations in the ongoing Ebola outbreak in the Democratic Republic of Congo (DRC) and Uganda, led by the Bundibugyo virus.

The findings, led by scientists from Imperial College London and the University of Oxford, are based on an analysis of 10 available Bundibugyo virus sequences from the Congo and Uganda associated with the current 2026 outbreak, according to Virological.org — an online discussion forum for pathogenic virus sequence data. The forum was launched in November 2014.

The sampled viruses appear to share a most recent common ancestor dating to early-to-mid March 2026, the researchers said.

"The sampled viruses are already genetically diverse. We identified 23 unique mutations across the 10 sequences," said Gina Cuomo-Dannenburg from Imperial College London and Mahan Ghafari from the University of Oxford.

"This level of diversity suggests that the sampled viruses do not represent the very beginning of transmission, but instead reflect an outbreak that had already been circulating, at least partly undetected, for several weeks before sequences became available," they added.

However, the authors noted that "this is an informal analysis and is not intended as a formal preprint or manuscript in its current form" and urged that the estimates "should be interpreted cautiously."

Ebola Cases Continue to Rise

Meanwhile, Congo said on Sunday that the number of confirmed Ebola cases had increased to 515 after 27 new samples tested positive in the previous 24 hours. The confirmed cases include 91 deaths, government data showed.

The Ministry of Health Uganda has confirmed 19 Ebola cases so far, including 14 imported from the DRC and five locally transmitted infections.

According to the World Health Organization, the latest outbreak has resulted in 516 suspected cases and 33 confirmed infections, with as many as 133 deaths reported.

CDC Warns Outbreak Could Rival 2014 Epidemic

The Ebola outbreak spreading through the Democratic Republic of Congo and Uganda could become more devastating than the largest Ebola epidemic in history unless containment efforts improve, according to modelling released by the US CDC.

The models, published in the Morbidity and Mortality Weekly Report, showed that the current outbreak could rival the scale of the 2014 West Africa outbreak, which resulted in more than 28,000 cases and over 11,000 deaths.

"That scale is possible," said Jason Asher, director of the CDC's Center for Forecasting and Outbreak Analytics, during a press briefing.

The worst outcomes could be avoided if "a larger proportion of patients were identified, isolated, and treated," the agency said in its reports.

However, "the public health response to control this outbreak will likely need to be of similar magnitude to the response for the 2014–2016 West Africa Ebola outbreak."

AI-Driven Drug Discovery

Also read: WHO Says Ebola Fight Is Catching Up; Expert Explains Science Behind Patient Recoveries

There are currently no approved treatments specifically for Bundibugyo ebolavirus, despite the existence of some antiviral therapies for other Ebola species. The rare strain is known to kill up to 40 percent of infected patients.

Scientists at the US' Southwest Research Institute (SwRI) have used AI-driven drug discovery platforms to rapidly identify and synthesize 23 antiviral candidates targeting the Bundibugyo Ebola strain currently affecting Congo.

The newly identified compounds are expected to undergo testing against the Bundibugyo virus in the coming weeks.

What Is Ebola?

Ebola is a severe and deadly disease caused by a virus mostly found in Africa. The spread of the disease happens through contact with infected body fluids.

Some symptoms can indicate a possible infection. This includes fever, headache, weakness, vomiting, diarrhea, muscle pain, sore throat, and unexplained bleeding. This eventually leads to severe complications like bleeding, organ failure, and death.

Christian Eriksen is a well-known name in the football world and has a huge following. When he collapsed during a friendly match between Denmark and Ukraine, it caused massive concern among the fans of the sport. The Danish Football Federation ensured the fans in a social media post that the veteran player has regained consciousness.

The federation wrote in their X post, “Christian Eriksen ‌is conscious and is doing well under the circumstances.” They also informed that the friendly match between Denmark and Ukraine was called off after this incident.

The football match was well into the 20 minutes of the second half when the incident occurred, and the players from both sides made a circle around the collapsed player. The fans were also in a hush, and medics attended to him on the field. He was eventually able to walk to an ambulance.

Team doctor of Denmark, Morten Boesen, told Danish media, “Christian is doing well and walked from the field himself. As I see it, the pacemaker is working as it should. He was briefly gone, but very quickly regained consciousness, and we were quickly in contact with him.”

Notably, this was not the first time that the midfielder collapsed during a match, as Eriksen suffered cardiac arrest during a European Championship match in Copenhagen in 2021. He was saved by CPR ⁠treatment. Later, he got fitted with a special heart-starting device known as an Implantable Cardioverter-Defibrillator (ICD).

What Is Cardiac Arrest?

Cardiac arrest happens when the heart suddenly stops pumping blood to the body, causing the brain and other organs to be deprived of oxygen. This ceases the function of the heart due to irregular heart rhythms, known as arrhythmias, which prevent the heart from functioning properly. Once the heart stops, blood flow to vital organs halts, leading to unconsciousness, respiratory failure, and, if not treated, can be fatal without treatment.

The condition is commonly referred to as a "silent killer" because it frequently occurs without obvious symptoms. When cardiac arrest happens, there is little time to react, and death can occur within minutes if emergency treatment, such as cardiopulmonary resuscitation (CPR) or defibrillation, is not immediately administered.

Cardiac arrest is a medical emergency, and quick action is essential for survival. The first step in treatment is performing CPR to manually compress the chest and encourage blood flow to the brain and other vital organs. If a defibrillator is available, it can deliver an electric shock to the heart, potentially restoring its normal rhythm.

Also Read: Cholera Outbreak In Nigeria: Death Toll Crosses 39, Cases Exceed 4,200

Why Athletes Are Prone To Cardiac Arrest?

Though heavy running and physical activity are widely believed and proven to be healthy habits, overexertion can cause great harm and can lead to undiagnosed or underlying cardiovascular abnormalities. Though this also depends on the age. Young players often face this problem due to a genetic condition, while older players mostly face it due to acquired coronary disease.

Shigella infection, commonly known as shigellosis, has claimed a 4-year-old's life in Kerala. According to reports from the authorities, three children were admitted to Kozhikode Medical College Hospital with this infection. Though two of them recovered and were discharged, a four-year-old girl, Nila, succumbed to the disease. She was from Thalakkulathur.

After this first fatality due to shigella, the state's health minister K Muraleedharan, addressed a press conference and said that shigella is a bacterial infection that mainly affects the intestines and causes symptoms such as diarrhoea, fever, and abdominal pain.

Muraleedharan said, "The disease mainly spreads through contaminated food and water. Strict hygiene practices are essential to prevent its spread." Then added, "Around 123 cases were reported in Alappuzha and Pathanamthitta districts last week."

The health minister also confirmed that Shigella was not the reason behind gastrointestinal illness among students in Wayanad. Around 164 students from educational institutions in the Sulthan Bathery region reportedly developed symptoms including vomiting and diarrhoea. Initially, there were concerns over them also being infected by Shigella, but preliminary tests showed that they were not infected.

Though he also added that a medical team from Kozhikode Medical College was dispatched to the area, and will collect samples for testing there. He said, "Initial reports suggest that the cases are not related to Shigella, but further testing is underway, and a final report is awaited."

The local authorities have also issued strict instructions on preventive measures. The health department has ordered the food safety department to conduct inspections, and hotels and eateries were instructed to maintain hygiene and ensure the provision of safe drinking water to customers.

The health minister stressed that the local self-government must take proactive measures to ensure public health.

Also Read: Lung Cancer Risk May Be Detected With Blood Marker 5 Years In Advance, Australian Study Finds

What Is Shigella?

Shigella is a highly infectious bacterium that causes gastrointestinal illness, commonly known as shigellosis. Its symptoms often include diarrhea, fever, and stomach cramps, which can range from mild to severe. Estimates suggest around 188 million cases occur each year, leading to over 1.6 lakh deaths due to Shigella throughout the world.

The infection spreads easily through contact with contaminated food, water, or surfaces, and through person-to-person transmission. Though it is a very infectious bacterium, certain groups are more vulnerable to infection. These groups include young children and people with weakened immunity. Notably, exposure risk increases in environments where hygiene practices may vary.

How To Prevent Shigellosis?

Early recognition and treatment with appropriate antibiotics is crucial to protect oneself from this disease. Notably, ORS can help prevent dehydration, while Zinc tablets can enhance recovery. Other measures to prevent the spread include washing hands with soap and water, especially before touching food, and after using the toilet, and maintaining hygiene. Controlling flies is also very important to prevent the disease.