The Union Health Ministry implemented a ban on 156 "irrational" FDC medicines, effective immediately. These medicines, including widely used antibiotics, painkillers, and multivitamins, were commonly used to treat fever, cough, and infections. The ban was imposed due to the associated health risks and lack of therapeutic justification for the ingredients in these FDCs.

What are FDC medicines?

FDCs or fixed-dosed combinations, also known as "cocktail drugs," are medications that combine multiple drugs in a single pill. They are designed to treat multiple symptoms or conditions simultaneously. While they offer convenience, they can pose significant risks. These risks include the possibility of overdose, adverse interactions between the drugs, and the development of antibiotic resistance. Additionally, many FDC medicines lack sufficient scientific evidence to support their safety and efficacy.

Expert opinions on FDC medicines

Experts have raised concerns about the use of FDC medicines. They believe that many of these combinations lack sufficient scientific evidence to support their safety and effectiveness. Additionally, the combination of multiple drugs in a single pill can increase the risk of adverse side effects and interactions with other medications.

Experts have also found that FDC medicines may not be as effective as individual drugs in treating certain conditions. It is important to note that safer and more effective alternatives are available for most of the medical conditions that FDC medicines were used to treat. One particular concern is the inclusion of antibiotics in some FDCs. Overuse of antibiotics can contribute to the development of antibiotic resistance, a major public health threat.

The risks of FDC medicines

The use of FDC medicines can lead to adverse effects, including serious ones. Additionally, safer alternatives, tested in clinical trials, are available to treat the same medical conditions. Experts recommend prescribing drugs individually based on a patient's clinical symptoms rather than combining them in FDCs.

The ban on irrational FDC medicines by the Union Health Ministry can be seen as a positive step towards promoting rational drug use and protecting public health. The goal is to eliminate unnecessary and potentially harmful drug combinations. This is a step forward in reducing the risks associated with medication and ensure safer and more effective treatment options for patients.

The Ebola outbreak in the Democratic Republic of Congo has crossed another grim milestone, with more than 6,000 confirmed cases and nearly 3,000 deaths. As of August 31, 2026, DRC had reported 6,041 confirmed cases and 2,911 deaths, according to government figures.

That puts the outbreak's case-fatality ratio at approximately 48.2%, meaning nearly one in every two confirmed patients has died. More than 1,360 people have recovered.

With Ituri remaining the epicentre, the outbreak, caused by the Bundibugyo species of Ebola virus, has spread across six provinces and nearly 60 health zones.

Mortality Rate Is Close To 50%

In its latest Disease Outbreak News update, the World Health Organization (WHO) reported a 48.1% crude case-fatality ratio as of August 26 and said the figure “underscores the severity of the disease”.

The number also highlights other issues like timely diagnosis, access to and quality of clinical care and containing transmission. Delayed diagnosis can be particularly dangerous as people may continue interacting with family members and healthcare workers while infectious.

WHO reported that 81 new confirmed cases were recorded in a single 24-hour period as of August 26. Ituri alone had recorded 4,802 confirmed cases by that point.

A nearly 50% case-fatality ratio does not mean that every person infected with Bundibugyo virus has a 50% chance of dying.

It is calculated from recorded cases and deaths and that can change as patients recover, die or are newly diagnosed. It is also be affected by how early cases are detected, access to treatment and whether infections are being missed.

Also read: Ebola Bundibugyo Virus: American Health Worker Had 10x Higher Viral Load In Throat Than Blood

Second-Largest Ebola Outbreak On Record

The US Centers for Disease Control and Prevention (CDC) says, "The DRC outbreak is spreading substantially faster than previous Ebola outbreaks” and is now the second-largest Ebola outbreak on record. The outbreak surpassed 1,000 confirmed cases within about 40 days of response activation, compared with approximately 235 days during the 2018 DRC outbreak.

The CDC says the response is being affected by limited healthcare infrastructure, ongoing conflict, violence against healthcare workers, shortages of protective equipment, population movement, mistrust and misinformation.

WHO Director-General Tedros Adhanom Ghebreyesus has repeatedly stressed that communities need to be at the heart of the response.

In a joint WHO-Africa CDC commentary published on August 25, Tedros, WHO Africa Regional Director Mohamed Yakub Janabi and Africa CDC Director-General Jean Kaseya wrote, “Ebola spreads through communities, and communities hold the knowledge required to stop it.”

Also read: Ebola Outbreak In DR Congo Records Its Highest Weekly Death Tolls Yet, With More Than 300 Deaths

Vaccine-Related Developments

Unlike Zaire strain, this outbreak is being caused by Bundibugyo virus, for which there is currently no vaccine or treatment. But researchers are in the process of testing vaccine and treatment on candidates.

Health authorities have also taken the unusual step of testing Ervebo, the vaccine licensed for Zaire Ebola, against the Bundibugyo strain.

WHO and Africa CDC announced in August that DRC would receive 70,000 Ervebo doses. Of these, 20,000 doses are intended for a Phase 3 clinical trial, while 50,000 are intended for frontline and healthcare workers under current recommendations.

WHO said, “It is not known whether Ervebo may be protective against the Bundibugyo virus in humans.”

Eli Lilly has made its latest move to look beyond the blockbuster GLP-1 market by agreeing to acquire biotech company Merida Biosciences for up to $2.875 billion in cash.

The deal will give Lilly access to Merida's experimental treatments for autoimmune and allergic diseases, including a potential drug for Graves' disease and thyroid eye disease. The transaction is expected to be completed in the fourth quarter of 2026, subject to regulatory approvals and other conditions.

The acquisition is another sign that Lilly is trying to diversify its pipeline beyond the obesity and diabetes medicines that have driven its recent growth. Lilly's spending on similar deals in 2026 that signals the company is looking to to expand beyond its successful hold on GLP-1 markets.

From Weight Loss Medications To Autoimmune Disease Drugs

Merida's lead programme, MER511, is currently in Phase 1 development for Graves' disease and thyroid eye disease (TED). The experimental treatment uses Merida's antibody-engineering platform to selectively remove pathogenic autoantibodies, the antibodies responsible for driving certain autoimmune diseases.

The idea is different from conventional immune-suppressing medicines, which dampen immune activity broadly. Initial Phase 1 data showed that MER511 substantially reduced thyroid-stimulating antibodies associated with Graves' disease and TED, while showing a favourable initial safety profile.

Francisco Ramírez-Valle, Lilly's senior vice president of immunology research and early clinical development, said, “We're building our pipeline around therapies that meaningfully change the course of disease, not just its downstream effects.”

He added that Merida's lead programme is designed to selectively and directly target the antibodies driving Graves' disease and thyroid eye disease.

Also read: Eli Lilly’s Foundayo Launched In UK: Is the GLP-1 Pill Better Than Wegovy, Mounjaro?

Different Drug Approach To Autoimmune Disease

In thyroid eye disease, inflammation can cause eye bulging, pain, double vision and, in severe cases, vision impairment.

Lilly's interest is specifically in Merida's approach is its attempt to target the disease-causing antibodies themselves, rather than suppressing the immune system more broadly.

Merida CEO Adam Townsend said, “Merida was founded to fundamentally change how autoimmune and allergic diseases are treated, by targeting the antibodies driving them directly, rather than suppressing the immune system broadly.”

That could potentially offer a more precise way of treating diseases in which specific autoantibodies are driving the damage.

Also read: Wegovy Is The Go-To Weightloss Drug Choice For Most US Teens

Lilly's Expanding Pipeline

The acquisition isn't only about Graves' disease. Merida's pipeline includes MER769, an experimental programme being developed for food allergy, asthma, chronic spontaneous urticaria and other allergic diseases.

The company also has earlier-stage programmes targeting kidney diseases and other conditions mediated by immunity.

This gives Lilly a potential base across a much broader range of immune-mediated diseases. The company that became synonymous with Mounjaro and Zepbound is trying to build a pharmaceutical portfolio that does not cash in entirely on the GLP-1 boom.

MER511 is still only in Phase 1, meaning its safety and preliminary biological activity are being evaluated in early clinical testing. The promising initial data do not yet establish whether the drug will ultimately work in larger patient populations or receive regulatory approval.

The $2.88-billion deal is therefore not Lilly buying an already-proven autoimmune medicine. It is buying a platform and the potential for an entirely new class of treatments.

As Townsend put it, “Joining Lilly gives our science the resources and commitment to realize its potential for patients with immune-mediated conditions.”

The NHS in England today announced that 100 pharmacies will offer free cholesterol check-ups beginning this autumn.

The initiative is part of an NHS drive to reduce heart disease and stroke deaths by a quarter over the next decade. It will include free finger-prick blood tests for cholesterol on the high street for the first time.

Who Is Eligible?

People aged 40 to 84 who are not pregnant and have not had a blood test in the past year will be eligible to walk in and get tested.

Eligible people will also be offered a blood pressure check as part of a clinical consultation with a pharmacist prescriber.

The NHS pilot will run until spring 2027.

How Will The Test Be Conducted?

Blood will be taken from a person’s fingertip using a lancet — a small, sharp medical tool used to prick the skin — and analyzed immediately. A pharmacist prescriber can then provide lifestyle advice and determine whether any treatment, such as statins, may be needed.

Patients will receive a copy of their results by email. They will also be offered a blood pressure check as part of a clinical consultation with a pharmacist prescriber.

How Will It Help?

The national rollout follows a successful smaller pilot in north London, which tested 2,493 patients at 61 community pharmacies between January 2025 and March 2026.

Nearly one in five patients were found to be suitable for pharmacological intervention, and 88 people started taking statins.

David Webb, the chief pharmaceutical officer for England, said pharmacies could be a vital first line of defense against serious illness.

He said: “By making it easier for people to get a quick and convenient cholesterol health check on their local high street, we can spot ticking timebombs earlier, helping people take action, and prevent heart attacks and strokes before they happen.

“This is the latest in a series of initiatives involving pharmacies in delivering care previously only offered in GP surgeries as part of the 10-year health plan to bring care closer to where people live.”

Will This Be Scaled Up?

In the first phase of the national rollout, about 100 NHS pharmacies across England will begin offering the checks from this autumn.

Dr Rani Khatib, NHS England’s national specialty adviser for cardiovascular disease prevention, said everyone should strive to be aware of the most common risk factors for heart disease, including high cholesterol and blood pressure, and “know their numbers”.

“This initiative will help people manage their risk factors earlier and reduce their risk of having heart attacks or strokes,” he said.

Alison McGovern, a health minister, said it was “exactly the type of innovation” she wanted to see across the NHS.

“We’re making it easier for people to spot potential problems earlier and take action to protect their health,” she said.

“Early detection can help prevent serious conditions such as heart attacks and strokes, helping people stay healthier for longer while reducing pressure on NHS services.”

How Does High Cholesterol Raise Heart Risks?

Too much LDL (“bad”) cholesterol in the blood can build up inside artery walls. Over time, these fatty deposits — called plaque or atheroma — can make arteries narrower and restrict blood flow, according to the NHS.

High cholesterol usually causes no symptoms, which is why testing is important. Cholesterol can be reduced through healthier eating and regular exercise and, for people at sufficient risk, medicines such as statins.