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Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
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The US measles outbreak is showing no signs of slowing down as it has reached new locations. A new case was recently reported in Wisconsin's Chippewa County, outside the state's main southwestern outbreak area, while Philadelphia health officials are warning of a possible measles exposure at the city's international airport.
The developments are crucial as measles cases continue to increase across the US, with Pennsylvania reporting hundreds of cases and Wisconsin recording 171 confirmed cases so far in 2026.
Wisconsin's Department of Health Services confirmed one measles case in Chippewa County on September 22. According to reports, the case has been attributed to out-of-state travel.
It means that it may not be connected to southwestern Wisconsin outbreak, where cases are concentrated. The state said no public exposure sites have been identified so far. The Chippewa County Health Department is working with the infected person and healthcare providers to identify anyone who may have been exposed.
“Measles is highly contagious, so confirming a case in our community is concerning,” Chippewa County Health Officer Brittnay Herrick said. “Our public health team is working closely with partners to identify potential exposures and ensure those affected have the information and guidance they need.”
Wisconsin has reported cases in Grant, Iowa, Lafayette, Marathon and Vernon counties since August. The state's largest cluster remains in southwestern Wisconsin, where 161 confirmed and six possible cases had been reported by September 18.
On the other hand, Philadelphia health officials are also warning travelers about a separate possible measles exposure at Philadelphia International Airport. According to health officials, an infected person walked through Terminals B and F, as well as areas connecting to Terminals C, D and E, between 7:25 p.m. on September 13 and 12:05 a.m. on September 14.
The person remained inside the airport and did not leave the premises. Health officials said the airport exposure is not connected to a separate measles exposure reported recently at Children's Hospital of Philadelphia.
Philadelphia Health Commissioner Dr. Palak Raval-Nelson said, “This week's measles exposures are a reminder of how important it is for all of us to be up to date on our vaccinations.” She added that fully vaccinated people are not at high risk from the suspected exposures.
People who were at the airport during the exposure period are being advised to check whether they are immune.
Those who are unvaccinated or unsure of their vaccination status, along with infants, pregnant people who are not immune and people with weakened immune systems, should contact a healthcare provider.
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Measles is among the most contagious infectious diseases. The virus spreads through the air when an infected person coughs, sneezes or breathes, and can remain in the air for up to two hours after the person has left an area.
Early symptoms typically include fever, cough, runny nose and red, watery eyes, followed several days later by a characteristic rash. Serious complications can include pneumonia, brain inflammation and, in some cases, death.
The Philadelphia Health Department says measles can be transmitted from four days before through four days after the rash appears, meaning an infected person can spread the virus before realizing they have measles.
People who may have been exposed should first find out if they are immune. Two documented doses of the MMR vaccine provide strong protection against measles. People who are not immune may be eligible for post-exposure treatment, depending on when the exposure happened.
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The Trump administration has canceled Obamacare health insurance enrollments covering more than 760,000 people, claiming the policies were linked to unauthorized enrollment. The move is part of a crackdown on fraud in the Affordable Care Act Marketplace.
The Centers for Medicare & Medicaid Services (CMS) said it canceled approximately 315,000 Marketplace enrollments on August 31, after investigations with insurers confirmed that the enrollments were unauthorized. The agency estimates that it will return about $2.2 billion in federal premium subsidies.
The administration is also investigating another 419,000 to 450,000 enrollees to determine whether they meet citizenship or immigration and income requirements. These people have not been found ineligible yet and are undergoing additional verification.
The authorities says it is targeting fraudulent, unauthorized and improper enrollments, rather than trying to eliminate Obamacare coverage itself.
CMS said it found that some people were enrolled without their knowledge, while others had unresolved identity, citizenship or immigration-status information. The agency also found applications missing information such as Social Security numbers.
Vice President JD Vance said the canceled group includes “a mix of both phantom people, but also real people who just don’t meet the eligibility requirements,” including some people who he said were enrolled by brokers without their knowledge.
CMS Administrator Mehmet Oz said some enrollees were classified as “phantoms” because officials believe they either did not exist or did not know they had coverage.
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The administration says the 760,000 people were covered by enrollments that CMS determined were unauthorized. But it does not mean every individual has committed fraud.
Some cases involve alleged actions by insurance agents or brokers. CMS says it found applications submitted without required applicant information and evidence that some consumers may have been enrolled without their authorization.
CMS has issued notices to 569 agents and brokers that it intends to terminate their agreements over applications that allegedly lacked key information. The agency says 66 had already received termination notices.
The administration has identified another group of approximately 419,000 to 450,000 people for additional verification.
Officials say they want to establish whether these enrollees are legally eligible for Marketplace coverage and whether they meet the income requirements for the federal subsidies.
CMS says newly registered brokers for the 2026 plan year accounted for a disproportionate share of the fraudulent Obamacare enrollments.
According to the agency, enrollments handled by these newer brokers were 2.8 times more likely to have unresolved income-verification issues, 2.7 times more likely to be missing Social Security numbers and 2.6 times more likely to have unresolved citizenship or immigration-status verification issues compared with brokers registered before 2026.
CMS has therefore imposed a temporary moratorium on new broker registrations for the 2027 plan year for agents and brokers without an active 2026 Exchange Agreement.
The move does not end the Affordable Care Act or eliminate Marketplace insurance. Instead, it represents a major tightening of how the federal government verifies who is enrolled and who qualifies for subsidies.
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More than five months after the UK’s worst meningitis B outbreak in Kent, scientists say they have identified genetic changes that may explain why the infection caused unusually severe disease.
According to UKHSA data, more than 20 young people, mostly students, were infected in the March outbreak linked to a Canterbury nightclub. All required hospital treatment; nine were admitted to intensive care and two died.
“This investigation shows just how quickly and dramatically these bacteria can change, sometimes acquiring new traits from harmless bacteria circulating nearby, that make them more likely to cause disease,” said Dr Charlene Rodrigues, Consultant in Pathogen Genomics at UKHSA.
Two people died in the outbreak — a 21-year-old University of Kent student and Juliette Kenny, a sixth-form pupil at Queen Elizabeth’s Grammar School in Faversham.
The outbreak is thought to have started at Club Chemistry, a nightclub in Canterbury city centre popular with university students. Scientists believe one person may have brought the infection into the venue, where it then spread through close social contact.
At the time, scientists described the outbreak as “unprecedented” and “explosive” because of its unusual speed and severity.
“The fact this outbreak variant was able to spread to so many young people was due to the social environment, a place where lots of close social mixing takes place,” Dr Rodrigues said.
Scientists from UKHSA, the University of Oxford and academic institutions used bacterial genome sequencing to investigate the outbreak.
UKHSA’s Meningococcal Reference Unit sequenced the bacteria within days of the first case and compared the outbreak strains with tens of thousands of meningococcal genomes in international databases.
They found that the outbreak strain had acquired DNA from less harmful bacteria naturally found in the human throat.
“This process is called ‘horizontal gene transfer’ and allows bacteria to pick up and incorporate small pieces of DNA from other bacteria in their environment, effectively borrowing genetic traits without direct reproduction taking place,” the scientists explained.
The changes appear to have altered how the strain interacts with human cells, making it more effective at causing severe disease and potentially harder for the immune system to recognize.
The same changes may also help explain why the strain has not continued to spread widely since the outbreak was controlled.
The findings were published as a pre-print and presented this week at the UKHSA Conference 2026 in Manchester.
The researchers compared the Kent outbreak with historical outbreaks, including one at the University of Southampton in 1997, and found similarities in how the bacteria evolved.
The team said highly invasive strains can emerge suddenly and unpredictably, meaning similar outbreaks could occur again, although exactly when and where is impossible to predict.
The findings highlight the importance of genomic surveillance, rapid public health responses, vaccination and awareness of meningococcal disease symptoms.
Meningitis is inflammation of the meninges, the protective membranes covering the brain and spinal cord. It can be caused by bacterial, viral, fungal or parasitic infections, as well as non-infectious conditions.
Bacterial meningitis can be severe and may lead to complications including hearing loss, vision problems and death if not treated promptly.
In infants, symptoms may include excessive crying, irritability, feeding difficulties, a bulging soft spot on the head and unusual lethargy.
Two doses of the MenB vaccine offer protection against meningococcal group B disease.
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