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Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
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A patient has received a pioneering stem cell treatment for Parkinson's disease in Japan, marking a world first following the therapy's conditional approval in the country.
Developed by Japanese drugmaker Sumitomo Pharma in collaboration with Dr Jun Takahashi at Kyoto University, the therapy, Amchepry (also known as raguneprocel), is the world's first induced pluripotent stem cell (iPSC)-based treatment for Parkinson's disease. It received conditional approval in March 2026 following successful clinical trial results.
The first transplant was performed at Kyoto University Hospital in October, the company said on Friday in an earnings press release, without providing further details, AFP reported.
Also read: Parkinson’s at 40: Why Younger Adults Are Being Diagnosed Earlier Than Before
The treatment uses iPSCs obtained from healthy donors, which are developed into precursors of dopamine-producing neurons and transplanted into the brain to replace cells lost due to Parkinson's disease.
iPSCs are created by reprogramming mature, specialised cells to return to an earlier state, allowing them to develop into different cell types.
Stem cell therapy, also known as regenerative medicine, uses stem cells or their derivatives to repair or replace damaged tissues.
What Did the Clinical Trial Find?
During the clinical trial, seven patients aged between 50 and 69 received implants of either five million or 10 million cells on both sides of the brain.
The patients were monitored for two years. Researchers found no major adverse effects, while four participants showed improvements in their symptoms, AFP reported.
Sumitomo Pharma said it plans to perform transplants in 20 to 30 patients by March 2029. The company is also conducting a clinical trial of the treatment in the United States.
The therapy will receive full approval in Japan if its safety and effectiveness are confirmed over the next seven years, according to local media reports.
Read More: Parkinson’s Disease: Women Have More Motor Complications, Depression
The announcement comes a month after a hospital in Osaka performed the world's first surgery using sheets of heart muscle cells derived from iPSCs.
The sheets are designed to promote new blood vessel formation and help restore heart function. The treatment also received conditional approval in Japan in March.
Conditional approval allows these therapies to be used clinically while additional data on their safety and effectiveness are collected.
Parkinson's disease is a progressive neurodegenerative disorder caused by the loss of dopamine-producing brain cells. It primarily affects people over the age of 60 and is estimated to affect more than 10 million people worldwide, according to the Parkinson's Foundation.
Dopamine plays an important role in controlling movement. Its loss can cause symptoms such as:
The disease can also cause cognitive decline, depression and anxiety. Currently available treatments help manage symptoms but do not stop or reverse disease progression, according to the Parkinson's Foundation.
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For the first time in nearly three decades, the US Food and Drug Administration (FDA) is proposing changes to nutrient requirements for infant formula. The proposed changes cover vitamins A and D, iodine and manganese under the Trump administration's Operation Stork Speed initiative, announced in March 2025.
The FDA’s first phase of a three-phase review covers eight of the 30 nutrients required in infant formula. It proposes revising requirements for four nutrients and reaffirming existing limits for the other four. It is also seeking public input on nutrients commonly added by manufacturers but not currently required. The agency is accepting comments for 120 days.
“Parents deserve confidence in every bottle they feed their baby,” US Health and Human Services Secretary Robert F. Kennedy Jr. said in a statement.
Also read: Major FDA Study Confirms Baby Formula In US Safe, Testing to Continue
The FDA's first phase covers eight nutrients. It proposes changes to four and retaining existing limits for the other four.
The FDA also proposes updating formula labelling requirements to reflect the changes.
Read More: New International Food Pyramid Highlights Plant Foods, Counters Trump’s Meat-Heavy Diet Advice
The FDA proposes retaining existing levels for:
The FDA says formulas currently sold in the US remain safe for babies. The proposed changes are not prompted by safety concerns but aim to align standards with current scientific evidence.
Parents do not need to change the formula they currently use.
The FDA is reviewing all 30 nutrients in three phases. The first covers eight, with the remaining 22 to follow.
The final rule will take effect 60 days after publication in the Federal Register. Manufacturers will have three years from that date to reformulate and relabel their products.
This means the proposed changes will not appear on formula packaging immediately.
Dr Steven Abrams, a paediatrician and professor at the University of Texas' Dell Medical School, called the update overdue. He described the first phase as “really well done” and “very well thought-out”, CNN reported.
However, he said the phased approach means manufacturers could take several years to implement the changes.
“These changes that they're recommending today are not going to be something that'll show up on the can of formula potentially for several years,” Abrams said.
He identified the proposed vitamin D increase as the most consequential change in this phase.
Meanwhile, the FDA is also seeking input on making commonly added nutrients such as DHA, ARA and L-carnitine mandatory. These are not currently required in infant formula.
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The Ebola outbreak in the Democratic Republic of Congo (DRC), officially declared a Public Health Emergency in May 2026, has surpassed 10,000 cases and is approaching 5,000 deaths, making it the fastest-growing Ebola outbreak in history.
Driven by the Bundibugyo Ebola virus, the outbreak has spread beyond the DRC to Uganda, Kenya and Nigeria, raising concerns about cross-border transmission. There is currently no licensed vaccine against this strain, although candidates are in development.
More than 1,000 children have died, accounting for over one-quarter of recorded fatalities, according to Save the Children.
“It's extraordinarily serious. Over 1,000 children have died of Ebola,” Greg Ramm, Save the Children's Country Director in the DRC, told the media.
“The world needs to start paying attention. We will break 15,000 deaths by the new year. And just because Ebola isn’t going to become a pandemic doesn’t mean it is not a global health security threat as well as a humanitarian disaster,” Dr Angela Rasmussen, a virologist, warned in a post on X.
Africa CDC Director-General Dr Jean Kaseya has warned that the outbreak's unprecedented geographical spread could put countries beyond Africa, including the UK, at risk.
“The geographic extension of this outbreak is unprecedented,” he said, noting that three African regions had been affected. Drawing parallels with COVID-19, he warned: “We don’t want to see the UK and other countries become the hotspot,” The Guardian reported.
In response, the UK Health Security Agency's (UKHSA) Dr Sam Collins stressed that the risk to the UK remains low and that the country “is well prepared to respond safely and effectively to the risk of imported cases arising here”.
Scientists have linked Ebola viruses detected in Kenya and Nigeria to those circulating in Beni, eastern DRC, raising questions about a possible shared transmission chain or an unidentified source, Bloomberg reported.
“Genomic sequencing shows that the Ebola virus from Nigeria’s recently reported only imported case is highly similar to that from Kenya’s first imported case, differing by only one mutation,” Muhammad Ali Pate, Nigeria's Coordinating Minister of Health and Social Welfare, said in a post on X.
Scientists from four countries, led by Congolese virologist Jean-Jacques Muyembe, analysed 1,126 viral genomes after an Ebola case was detected in Abuja, Nigeria.
The Beni samples share a distinctive genetic signature, including a mutation absent from other sequenced viruses from Congo.
The viruses also lack genetic markers associated with Uganda's documented Ebola transmission chains from May and June, suggesting they did not descend from those previously identified outbreaks.
Researchers have yet to establish where the patients contracted the virus or whether they were infected through the same transmission chain. Genetic sequencing alone cannot prove direct transmission.
Investigators are examining the patients' movements through Uganda during their potential exposure periods.
The Nigerian patient was in Uganda from September 15 to October 3 and developed symptoms three days after returning to Abuja. The Kenyan patient travelled from Congo through Uganda between October 1 and 3 before flying to Nairobi from Entebbe.
Both patients reportedly travelled on flights on October 3. Authorities are checking their travel records for possible overlap and tracing potentially exposed passengers.
Nigeria has traced 62 contacts of the infected woman, NCDC Director-General Jide Idris said. Of these, 50 are in isolation, five are being monitored at home and seven remain unlocated.
Uganda recorded 20 confirmed cases and two deaths before declaring the outbreak over in June.
Kenya has reported nine cases and two deaths. Seven patients, including three family members and four healthcare workers, are receiving treatment and responding well. Authorities have traced all 135 contacts linked to the first case, according to official data.
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