Can Weight Loss Drugs Curb Alcoholism? See What Study Says

Updated Feb 13, 2025 | 09:02 AM IST

SummaryResearchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
Can weightloss drug curb alcoholism?

Credits: Canva

Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.

What Do Studies Say?

The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.

The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.

The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.

The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.

How Was The Study Conducted?

The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.

Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."

Why Does It Work So Well Against Alcoholism?

The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.

However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.

End of Article

Can Testosterone Fight Brain Tumour?

Updated Jun 5, 2026 | 04:00 PM IST

SummaryTestosterone is the key male hormone that affects reproductive health in men, along with hair health and muscle mass.
Brain tumour

Testosterone regulates defence cells in the brain. (Photo credit: AI generated)

Recent research is changing our understanding of testosterone's role in brain cancer, particularly glioblastoma. A study published in Nature in May 2026 made this finding, altering previous understanding. Dr. Vishnu P. S., Consultant Neurosurgeon, Dr. KM Cherian Institute of Medical Sciences, Chengannur, in an interview with Health and Me, explained the impact of testosterone in fighting brain tumours.

This study, conducted under the National Institutes of Health with a group of researchers from the Cleveland Clinic, turned decades of medical thinking on its head. They discovered that testosterone actually slows down brain tumour growth in men. This breakthrough could totally change how we treat glioblastoma.

This study found that drops in testosterone ramp up inflammation and activate the HPA axis, producing stress hormones that speed up tumour growth. Analysing data from over 1,300 men with the deadly disease glioblastoma, researchers observed a significant benefit for those on testosterone supplements: they had a 38% lower risk of dying compared to those who were not receiving the extra hormone.

How Testosterone Protects the Brain

Testosterone usually regulates microglia, which are defense cells in the brain. When testosterone levels drop, especially in older males, these cells increase inflammation, making the brain less able to fight off issues such as tumours. Removing testosterone in preclinical tests on mice accelerated tumour growth, but restoring it slowed things down again.

The Change Everyone Is Surprised By

This finding shifts what everyone used to think. Previously, people believed testosterone helped tumours grow. But now, that idea has been turned on its head. What was once seen as harmful is now understood to be protective, suppressing brain tumours instead. Plus, the hormone works differently in the brain compared to other parts of the body and helps regulate protective systems there.

In India, this matters a great deal because men develop glioblastomas more often than women do (with a 3:2 ratio). This new finding could totally change how doctors treat patients here, especially older males whose androgen levels are lower and who already have a higher risk of developing this type of cancer.

What This Means for Patients

Glioblastoma continues to be one of the most difficult cancers to treat, with limited improvements in survival rates despite surgery, radiotherapy, and chemotherapy. However, this new research suggests that hormones can influence the brain’s immune and stress responses. This might lead to new treatment pathways, especially since androgen levels naturally decline in older men as they age.

Still, caution is needed. The relationship between testosterone and cancer is complex and has produced mixed results. Because of this, doctors do not recommend self-medicating or using hormone therapies unless under close medical supervision or as part of clinical trials. At present, it is more about viewing this as a promising step forward that could offer hope to the millions of patients and families dealing with this devastating illness.

End of Article

Ebola Alert In India: Rajasthan Reports First Suspected Case of Deadly Virus

Updated Jun 5, 2026 | 04:25 PM IST

SummaryAccording to the Ministry of Health, there are currently no confirmed Ebola cases in India. As part of precautionary measures, travelers entering India from such nations are required to undergo a 21-day quarantine period.​​
Ebola Alert In India: Rajasthan Reports First Suspected Case of Deadly Virus

Credit: AI generated image

Amid the ongoing Ebola outbreak in Africa, Rajasthan has reported its first suspected case of the Ebola virus.

According to the Ministry of Health, there are currently no confirmed Ebola cases in India.

A woman who arrived in the state from Uganda has shown symptoms consistent with Ebola infection, according to media reports.

Woman Isolated After Airport Screening

The woman reportedly arrived in Jaipur from Sharjah on an Air Arabia flight and landed at Jaipur airport around 4:30 a.m.

Also Read: The Mystery Behind Trump’s Hair-Loss Drug And The Bigger Health Questions It Raises

During routine health screening at the airport, she exhibited symptoms associated with Ebola infection. The health department was immediately informed, and she was placed under special observation.

She has since been admitted to Rajasthan University of Health Sciences (RUHS) Hospital in Jaipur and kept in isolation as a precautionary measure.

Following the suspected case, the state Health Department has been placed on alert and is closely monitoring the situation.

Samples Sent to NIV Pune for Testing

Also read: Ebola: Inside India’s RT-PCR Tests For The Bundibugyo Strain| Explained

RUHS Hospital Superintendent Dr. Anil Gupta told the media that Ebola infection has not yet been confirmed in the woman. Her samples have been sent to the National Institute of Virology (NIV) in Pune for testing.

While she has displayed symptoms similar to Ebola infection, confirmation can only be made after laboratory testing. The results are expected by this evening or tomorrow morning.

Meanwhile, doctors have begun treatment and monitoring under a special protocol.

Health Ministry Issues Advisory

"No Ebola disease cases have been reported in India," the Health Ministry said in its latest update on June 3. However, the ministry has advised travelers arriving from Ebola-affected countries, including Uganda and the Democratic Republic of Congo, to remain alert for symptoms and seek medical guidance if they feel unwell.

"For information, guidance and assistance, call MoHFW's 24x7 Health Helpline: 1075," the ministry said on X.

The Directorate General of Civil Aviation (DGCA) and the Ministry of Civil Aviation have implemented strict screening and monitoring measures at airports across India.

The government has also issued guidelines for passengers arriving from Ebola-affected countries. As part of precautionary measures, travelers entering India from such nations are required to undergo a 21-day quarantine period.

Ebola Alert In India: Rajasthan Reports First Suspected Case of Deadly Virus

In late May, several suspected Ebola cases were reported from Gujarat, Bengaluru and Madhya Pradesh. All later tested negative for the virus. All the suspected infections involved individuals with travel links to Ebola-affected countries.

Ebola has been declared a Public Health Emergency of International Concern (PHEIC) by the World Health Organization (WHO). In a major relief amid the ongoing outbreak, the WHO said dropped the number of suspected cases to 116 after hundreds were ruled out following investigation.

Earlier, the number of suspected cases had neared 1,000 in the Democratic Republic of Congo (DRC).

The global health agency said that there had been 48 deaths and six recoveries in Congo, Reuters reported. In Uganda, there have been 15 confirmed cases and one associated death.

Expert Questions Travel Policy

Mumbai-based infectious disease expert Dr. Ishwar Gilada questioned why India continues to allow travelers from countries experiencing Ebola outbreaks.

"Our policy should be so strict that we do not allow anybody coming from those kinds of countries where there is already an outbreak of Ebola, because Ebola has neither a treatment nor a cure nor a preventive vaccine," Dr. Gilada told HealthandMe.

What Is Ebola? How Does The Disease Spread?

Ebola disease is a severe viral hemorrhagic fever with a high mortality rate. Ebola spreads through:

  • Direct contact with infected blood or bodily fluids
  • Contact with contaminated surfaces or medical equipment
  • Unsafe caregiving exposure
  • Traditional burial practices involving direct contact
  • Certain zoonotic animal exposures.

Symptoms to watch for include:

  • fever,
  • weakness,
  • headache,
  • muscle pain,
  • vomiting,
  • diarrhea,
  • sore throat,
  • unexplained bleeding.

End of Article

Alan Brazil Shares Survival Story After Heart Stopped During Liver Transplant

Updated Jun 5, 2026 | 04:20 PM IST

SummaryA liver transplant is a surgical procedure to replace a diseased liver with a healthy one from a donor. It’s often the last resort when liver failure occurs—whether due to chronic illness or sudden injury.
Alan Brazil Shares Survival Story After Heart Stopped During Liver Transplant

Credit: Alan Brazil/Instagram

Former Scotland striker Alan Brazil revealed that he has had a liver transplant and that his heart stopped during the surgery.

"My heart stopped for a bit," said Brazil, who described himself as "incredibly lucky" to have survived a life-saving liver transplant surgery.

He announced his surgery last month, after disappearing from the airwaves while covering the Cheltenham Festival in March.

During the video announcement, he also revealed a transformation in appearance, having lost weight during the process of the transplant, The Telegraph reported.

“I’d been having ongoing trials, so many specialists, and I decided I needed a transplant. I didn’t want to do it, but my kids and Jill [his wife] said, ‘You’ve got to do it, you have to do it, you are doing it," said the 66-year-old, in his first appearance on the radio station since leaving.

"I finished [work] at quarter to 10, and at 10 I had to phone Addenbrooke's Hospital. They said, 'Get in right now'".

Also read:I’m Cancer-Free After 14 Years, Says Robin Quivers

"At two thirty that afternoon, I was on the slab, and they opened me up. I was under for something like eight hours.

"They transplanted my liver. My heart did stop for a bit, and it came back on its own. I'll be frank, I'm very, very lucky to be here," said Brazil, who has presented Talksport’s breakfast show since 2000.

He further said: “I’m taking loads of meds ...I’ve just got to be a good boy, rest up, and go and see these people. Hopefully, I’ll get back to 100 per cent. I never realized how bad I was. I feel totally different now. I’m incredibly lucky.”

What Is A Liver Transplant?

Read more: Forget Supplements: Barbara O'Neill Says Sleep Is The Best Medicine

As per the National Institute of Diabetes and Digestive and Kidney Diseases, a liver transplant is a surgical procedure to replace a diseased liver with a healthy one from a donor. It’s often the last resort when liver failure occurs—whether due to chronic illness or sudden injury.

When Is It Needed?

People may need a liver transplant for:

  • Alcoholic liver disease
  • Fatty liver disease (NASH)
  • Cirrhosis due to chronic hepatitis C
  • Liver cancer with cirrhosis
  • Acute liver failure (often due to drug overdose, hepatitis, or toxins)

In children, biliary atresia is the most common reason.

Types of Liver Transplants

Deceased Donor Transplant:

The most common type is where a full or partial liver is taken from someone who has recently died.

Living Donor Transplant:

A healthy person donates a portion of their liver—typically to a close relative. Both the donor’s and recipient’s liver regenerates to normal size in a few weeks.

What Must Be Kept In The Mind?

  • Matching and Compatibility: Blood type, liver size, and health are crucial.
  • Approval Process: Especially important for non-blood relatives.
  • Recovery and Monitoring: Post-op care involves lifelong medication, lifestyle changes, and regular check-ups.

End of Article