Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.

What Do Studies Say?

The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.

The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.

The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.

The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.

How Was The Study Conducted?

The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.

Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."

Why Does It Work So Well Against Alcoholism?

The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.

However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.

The Ebola outbreak in the Democratic Republic of the Congo (DRC) has reached another concerning milestone. With a surging number of deaths and confirmed infections, the healthcare workers in the affected regions have threatened to declare a strike due to nonpayment of dues, making it challenging to contain a deadly and aggressive outbreak.

DRC Ebola Death Toll Reaches 600 With 1759 Confirmed Cases

According to Reuters, the total confirmed number of deaths due to Bundibugyo Ebola has reached 600, with 1,759 confirmed infections as of July 9.

This comes amid protests demonstrated by healthcare workers in the affected regions, who have threatened to walk off the job due to months of unpaid wages and unsafe working conditions.

The outbreak initially affected Ituri, North Kivu and South Kivu provinces, but authorities are now investigating suspected cases in Tshopo province, including Kisangani, sparking concerns that new areas may be affected.

The outbreak, caused by the Bundibugyo species of the Ebola virus, has been spreading rapidly since it was declared on May 15.

Unlike the Zaire strain, there is currently no approved vaccine or specific treatment for Bundibugyo Ebola virus, making containment and treatment efforts particularly challenging. Currently, experimental therapies are being examined through ongoing clinical trials.

Also read: Uganda Says Ebola Is Contained After Nearly Two Months Of Outbreak; Seeks To Get Travel Restrictions Removed

Healthcare Workers Protests

The worsening outbreak could be even more challenging to contain as the frontline healthcare workers, including treatment staff, laboratory personnel, and burial teams, have been protesting nonpayment of salaries, insufficient protective equipment, and difficult working conditions.

According to several reports, many workers say they have not been paid since the outbreak began nearly two months ago. While some have already stopped working, others have warned that a mass walkout could further weaken the country’s Ebola response.

The administrative disruption significantly threatens critical epidemic operations like patient care, lab testing, contact tracing, and safe burial procedures, all of which are essential for slowing transmission and effectively containing the outbreak.

WHO Says Ebola Outbreak Is Still In Expansion Phase

The World Health Organization has repeatedly warned that the outbreak remains in an “expansion phase” due to several reasons, including overwhelmed treatment facilities, population movement, and delays in identifying and isolating infected individuals.

WHO also said that the treatment centers in some of the hardest-hit regions are operating near 90% capacity. Infection cases among healthcare workers are another concern that highlights the risks faced by frontline responders.

Misinformation about the disease has been rife in several Congolese communities. According to the Council on Foreign Relations, there have been reports that some local communities believe that the disease is a hoax or was brought into the country by Western aid workers who wanted to make a profit.

While Ebola is not a new disease, the current outbreak poses a significant threat because it is caused by a rare strain of the virus, Bundibugyo. The rarity of the strain has created scientific and emergency public health challenges, as there is currently no licensed vaccine to protect against the Bundibugyo Ebola virus.

Danish pharmaceutical giant Novo Nordisk has launched Awiqli (insulin icodec) in India, introducing the world's first once-weekly basal insulin for adults with diabetes.

Individuals with Type 2 diabetes require daily insulin to manage their blood glucose when diet, exercise, and oral medications are no longer sufficient.

The daily basal insulin injections are typically taken once every 24 hours. But Awiqli is designed to provide background insulin support throughout the week, reducing the ‌number ⁠of injections from 365 per year to 52, Novo said.

More than 101 million people in India are living with diabetes, ⁠while another 136 million have prediabetes, Novo said in a statement.

Insulin initiation in India is delayed by an average of 7-9 years, partly due to fear of injections, anticipated pain, and cost concerns, it said.

"We believe Awiqli will reduce the psychological and physical barriers to insulin initiation," Novo Nordisk India Managing Director Vikrant Shrotriya said.

Also read: Can Ozempic-Like GLP-1 Drugs Slow Aging, Boost Longevity?

What is Awiqli?

Awiqli (insulin icodec) is a long-acting basal insulin designed to help adults with diabetes maintain stable blood sugar levels with just one injection every week. It is administered using the Awiqli FlexTouch pen on the same day each week.

The treatment is intended to simplify insulin therapy, potentially improving treatment adherence among people who struggle with daily injections.

Global Approval

Earlier this year, the US Food and Drug Administration (FDA) approved Awiqli (insulin icodec-abae) 700 units/mL as the first and only once-weekly basal insulin for adults with type 2 diabetes. The therapy is indicated as an adjunct to diet and exercise to improve glycemic control.

The approval offers a new treatment option for patients seeking an alternative to daily basal insulin, allowing diabetes care to be tailored to different lifestyles and treatment preferences.

"Awiqli may address challenges associated with the frequency of daily basal injections by reducing them from seven to one per week. It is an important advancement for adults with type 2 diabetes who may benefit from an alternative treatment option," said Anna Windle, Group Vice President, Clinical Development, Medical & Regulatory Affairs at Novo Nordisk Inc.

Where Is It Available?

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The therapy has now been launched in India. Awiqli has also received regulatory approval in the US, the European Union, and 13 other countries, with indications varying according to local regulatory approvals.

Clinical Evidence

The approval is supported by Novo Nordisk's ONWARDS Phase 3a clinical program, which enrolled nearly 2,680 adults with uncontrolled type 2 diabetes across four randomized, active-controlled trials.

The studies compared once-weekly Awiqli with daily basal insulin and demonstrated effective reductions in HbA1c, a key measure of long-term blood sugar control. The overall safety profile was found to be consistent with existing daily basal insulin therapies.

Who Can Use It?

Awiqli is prescribed for adults with diabetes and should be used exactly as directed by a healthcare professional.

Patients should inject the medicine once every week on the same day. The dosage should not be adjusted without medical advice, the company said.

Are There Any Side Effects

Like other insulin therapies, Awiqli may cause side effects, including:

• Low blood sugar (hypoglycemia)
• Injection-site reactions
• Weight gain
• Skin thickening or pitting at injection sites (lipodystrophy)
• Allergic reactions
• Swelling of the hands or feet

Patients are advised to monitor their blood sugar regularly and seek immediate medical attention if they experience symptoms of severe allergic reactions or persistent hypoglycemia.

Who should not take Awiqli?

Do not take Awiqli if you:

• are having an episode of low blood sugar (hypoglycemia)
• have an allergy to Awiqli or any of the ingredients in Awiqli.

Global cancer cases could reach nearly 35 million a year by 2050, without urgent action to improve cancer prevention, early diagnosis and access to treatment, according to the World Health Organization (WHO) Global Status Report on Cancer 2026.

The report warns that cancer remains the world's second leading cause of death, claiming more than 26,000 lives every day and nearly 10 million annually.

The report, jointly released by the WHO and the International Agency for Research on Cancer (IARC), warned that major inequalities in cancer prevention, diagnosis, treatment and supportive care continue to leave millions of people without access to life-saving services.

It also noted that ageing populations, population growth and persistent health inequalities are driving the cancer cases.

"Cancer is a deeply personal disease that touches nearly all of us. But whether a person survives cancer should never depend on where they were born or what they earn," said WHO Director-General Dr Tedros Adhanom Ghebreyesus.

"The inequities documented in this report are not inevitable; they are the consequence of choices, and they can be reversed through stronger and unified action."

Global Status Report on Cancer 2026: Key Findings

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Cancer survival varies sharply across countries

The report highlights major disparities in cancer outcomes.

• 87% of women diagnosed with breast cancer survive at least five years in high-income countries.
• In low-income countries, the five-year survival rate falls to around 42%.
• Fewer than one in three countries include comprehensive cancer care under universal health coverage.

Cancer places a heavy financial burden on families

Beyond its health impact, cancer also creates significant economic and emotional challenges.

• At least 45% of people living with cancer experience financial hardship.
• More than half report mental health challenges.
• Nearly all caregivers experience strain, including unpaid caregiving responsibilities and social isolation.

Read More: US Cyclospora Parasite Outbreak Nears 900 Cases: Experts Say Handwashing Key to Prevention

Which Regions Have the Highest Cancer Burden?

The report shows that the burden of cancer varies significantly across regions.

Asia

• Accounts for 50.7% of global cancer cases.
• Records 56.5% of cancer deaths worldwide.

Europe

Although home to only about 9% of the world's population, Europe accounts for:

• 21% of global cancer cases.
• 20% of global cancer deaths.

Africa

Many African countries continue to experience comparatively lower cancer incidence but disproportionately higher mortality because of delayed diagnosis and limited access to treatment.

Most Common Types of Cancer Worldwide

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According to the WHO report:

• Lung cancer remains the leading cause of cancer deaths globally.
• Among men, the most common cancers are:
  • Lung
  • Prostate
  • Colorectal
• Among women, the leading cancers are:
  • Breast
  • Lung
  • Colorectal

Nearly Four in Ten Cancer Cases Are Preventable

The report estimates that almost 40% of cancer cases worldwide are linked to preventable risk factors, including:

• Tobacco use
• Alcohol consumption
• High body weight
• Physical inactivity
• Human papillomavirus (HPV)
• Hepatitis B and Hepatitis C infections
• Helicobacter pylori infection

WHO's Recommendations to Improve Global Cancer Care

The WHO has urged governments, health organizations, researchers and the private sector to work together to strengthen cancer care through three broad priorities:

Better capabilities

• Integrate cancer control into universal health coverage.
• Invest in cancer prevention, early detection and the healthcare workforce.

Better protections

• Put people living with cancer and caregivers at the centre of health systems.
• Expand financial and social protection for affected families.

Better value

• Align cancer research and innovation with public health priorities.
• Ensure equitable access to effective, evidence-based cancer treatments worldwide.