Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.

What Do Studies Say?

The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.

The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.

The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.

The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.

How Was The Study Conducted?

The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.

Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."

Why Does It Work So Well Against Alcoholism?

The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.

However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.

Prostate cancer is a big issue now in the United Kingdom, as the nation is witnessing 64,000 men diagnosed and 12,000 dying each year from this deadly disease. The statistics show that one in eight men will get prostate cancer in their lifetime, but for black men, that risk doubles to one in four.

As a preventive measure to find better ways of testing for the disease, tens of thousands of black men are invited for prostate cancer checks as part of an ongoing trial where the age group is between 45 and 74.

This crucial move has been taken after the minister considered the UK National Screening Committee's recent recommendation that most men should not be offered regular testing for the disease.

The committee stressed that the blood test for detecting prostate cancer, called PSA, is more harmful than its benefits, except for a few men who have a dangerous genetic variant and a family history of cancer.

The government is proactive about this major health issue and stated that it will invest 18 million pounds to transform the trial.

The research aims to determine whether other tests and procedures, alongside PSA, can be used in the screening process. In this study, they will check whether genetic checks and faster MRI scans can be used with greater accuracy,

Health Secretary James Murray said, "This is a major step forward in how we tackle prostate cancer - focusing on those most at risk, improving the treatments available, and backing the research we need to close the evidence gaps and save lives."

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What is the prostate, and how is screening done?

The prostate is a small walnut-shaped gland in men that produces seminal fluid, which nourishes and transports sperm. Prostate cancer develops when abnormal cells begin growing in the gland.

Though not all prostate cancers are life-threatening. Some forms grow very slowly and may never affect a man’s lifespan. Such slow-growing cancers are found in around one in three men over the age of 50.

However, a smaller number of prostate cancers are aggressive, spread rapidly, and can become life-threatening, making timely detection important.

Also Read: Prostate Cancer Screening In UK To Focus On High-Risk Men; Guidelines Reject Universal Testing

Screening typically involves a blood test called prostate-specific antigen (PSA). Depending on the results, patients may then undergo an MRI scan of the prostate.

However, screening healthy men can sometimes lead to overdiagnosis and unnecessary treatment, which may result in side effects such as erectile dysfunction and loss of bladder control.

A major review by the National Screening Committee found that for every 1,000 men screened in their 50s, two prostate cancer deaths could be prevented over 15 years.

But the same screening could also result in 20 men being diagnosed with cancers that would never have required treatment. Of those 20 men, 12 could undergo unnecessary treatment that may damage the prostate, affect sexual function, or cause urinary incontinence.

The New World Screwworm fly is a devastating tropical species that majorly infects cattle but can also be harmful to humans in some cases, and this problematic species, after being contained in the southern states of the US, is suspected to return once again, according to the officials of the United States Department of Agriculture (USDA).

This debut may cause mayhem in the cattle industry. The USDA has posted on the social platform X that it was testing a sample from a potential infestation of the fly’s flesh-eating larvae at its national veterinary lab in Iowa. The exact location of this suspected case has not been stated.

U.S. Agriculture Secretary Brooke Rollins also said on social site X that she has met with Texas officials, including Gov. Greg Abbott, about 50 cattle ranchers. She added that the potential case was “being fully contained.”

This very important announcement came just after Rollins held an online news conference to shed light on the proximity of the threat, as it was detected in Mexico, only 25 miles from the state.

New World Screwworm Fly

New World Screwworm Fly is an invasive tropical species whose females lay eggs in open wounds or mucous membranes. These eggs then hatch and eat flesh. This trait makes them a unique flying species. This species is known to infest livestock, wild mammals, and household pets. Though it's rare, humans can also be infested by this threatening species.

The recent case of Maryland, where federal health officials confirmed that a person got infested by this fly after visiting El Salvador, but the patient recovered soon. The last large-scale infestation happened in 2016 when it spread among wild deer in Florida.

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How To Contain This Dangerous Species?

The infestation of this invasive species has been done before, and the process involves breeding sterile male flies and releasing them to mate. This process completely eradicates the population. In 2024, this very species was contained in Panama by this same process.

Also Read: US CDC Health Alert: Deadly Risks and Infections Linked to Cosmetic Surgeries Abroad

What is the USDA Doing To Prevent Outbreaks?

The USDA is very active and cautious about this possible outbreak in the states; it has dedicated 21 million US dollars to convert a fruit-fly breeding facility in southern Mexico into one for breeding screwworm flies. It has also opened a new center for dispersing sterile flies bred elsewhere in southern Texas. Along with these, the government agency is building a screwworm fly factory in Texas with 750 million.

The Agriculture Secretary was also alarmed by this possible outbreak and ceased cross-border livestock import from Mexico last year. She has stressed that pets can travel across borders with families and can get infected. The wild animal can also travel through the border and get infected with it and return. Though the US authorities have assured, stating, “Our food supply is 100 per cent safe.”

The US Centers for Disease Control and Prevention (CDC) has given a warning on having cosmetic surgeries in foreign nations, as it can cause serious infection, even in some cases, death.

CDC, in its report, has shed light on the fact that aesthetic surgeries such as breast augmentation, liposuction, and other elective procedures are performed both within the United States and abroad. This cosmetic enhancement is causing growing concern for public health.

CDC’s journal Emerging Infectious Diseases also published a study regarding the danger and fatality surrounding the beauty enhancement surgeries. This study screened over 2,100 reports of U.S. citizens who travelled in foreign nations between 2014 and 2024.

This CDC research identifies 21 reports involving approximately 145 patients who experienced severe adverse health effects after undergoing beauty enhancement procedures within and outside the US. Notably, four out of these patients even died due to having these surgeries.

The report also mentioned the reasoning behind this alert, as many of these clinics and facilities are causing infections and even death due to their outdated and careless infection-control practices, which include improper environmental cleaning, lack of use of personal protective equipment, a shortfall in hand hygiene, and repeated use of some surgical instruments.

Kiara McNamara, a CDC nurse epidemiologist and lead author of the study, said, “More and more people are getting medical procedures outside the United States, but there are risks.”

The CDC has urged U.S. nationals to research thoroughly before having cosmetic procedures in healthcare facilities abroad.

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Norovirus Spreading Across the U.S.

The United States is once again witnessing a surge in norovirus infections, a highly contagious gastrointestinal illness that causes severe vomiting and diarrhea.

Media reports noted that hikers along Southern California's Pacific Crest Trail have been hit by a fast-spreading outbreak of what is often referred to as the "winter vomiting disease".

At least two dozen hikers have fallen ill along the trail over the past two weeks, resulting in at least one air rescue. Health officials believe the cases are linked to norovirus, USA Today reported.

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In addition, the latest data from the US Centers for Disease Control and Prevention's National Respiratory and Enteric Virus Surveillance System also showed that norovirus cases have increased over several weeks following a sharp seasonal decline that began in March.

About 11.2 per cent of administered norovirus tests returned positive during the week ending April 28. That figure rose to 12 per cent in the week ending May 2.

Norovirus is commonly associated with the colder months, when respiratory illnesses such as flu and the common cold are widespread.

However, health experts note that late-spring increases in norovirus activity are not unusual, and outbreaks can occur throughout the year due to the virus's highly contagious nature, the report said.