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Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
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In a major policy shift, schools and colleges across India are set to introduce comprehensive sex education after the Centre informed the Supreme Court that a nationwide programme on health, safety, relationships and reproductive awareness will soon be rolled out.
The move comes nearly two years after the apex court directed the government to create a structured national framework to improve awareness about sexuality, reproductive health, consent, personal safety and child sexual abuse prevention.
Appearing before a bench of Justices BV Nagarathna and R. Mahadevan, Additional Solicitor General Aishwarya Bhati said the Centre has accepted the recommendations of a 26-member national expert committee. The government plans to implement the curriculum nationwide after the Supreme Court grants its formal approval.
The bench also observed that "sex education is not a Western concept incompatible with Indian societal values," noting that misconceptions have led some states to oppose or ban such programmes despite their public health importance.
The expert panel has recommended making comprehensive sex education a mandatory part of the school curriculum under NEP 2020. Specially trained teachers would conduct brief 15–20 minute sessions twice a week, with lessons tailored to each age group.
Primary school: Personal hygiene, body awareness, and safe and unsafe touch.
Middle and higher classes: Puberty, hormonal changes, consent, personal boundaries, recognising unsafe situations, seeking help, and reproductive and sexual health.
Health experts lauded the move and reiterated that comprehensive sex education is not about encouraging sexual activity. Instead, it equips children with the knowledge and life skills needed to stay safe, make informed decisions and build healthy relationships.
Speaking to HealthandMe, Dr. Ishwar Gilada, the President Emeritus of the AIDS Society of India (ASI) and a Governing Council member of the International AIDS Society (IAS), called the apex Court's directions a landmark moment after decades of advocating for scientific sex education.
He noted that "early sex education can help prevent child sexual abuse among both girls and boys", and also prevent sexually transmitted diseases (STDs) and HIV.
A key myth about sex education is that it will encourage sexual activity. Busting the myth, Dr. Arti Anand, Senior Consultant, Clinical Psychology, Sir Ganga Ram Hospital, said that "comprehensive sex education is about providing children with the right information at the right age, not encouraging sexual activity".
The experts noted that in the absence of accurate information, children often rely on friends or the internet, where myths and misinformation are common.
Instead, Dr Arti said that a good sex education can:
Studies have proven that comprehensive sexuality education can:
Dr. Amit Prakash Singh, Consultant – Internal Medicine, CK Birla Hospital, Delhi, described comprehensive sex education as an essential life-skills programme that goes beyond reproductive health.
Dr. Singh told HealthandMe that the curriculum will help children understand:
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South Korea is experiencing a sharp rise in sleep disorders across all age groups, but the fastest increase is among its youngest population.
New government data suggests that the number of children under the age of 10 who are undergoing treatment for sleep disorders spiked by 67.5% over the past four years, compared to teenagers and adults.
The surprising trend has raised concerns among pediatricians and sleep experts, who warn that poor sleep habits in early childhood can have permanent effects on physical growth, learning, intelligence, emotional well-being, and mental health.
According to figures released by South Korea's Health Insurance Review and Assessment Service (HIRA), more than 1.34 million people sought treatment for sleep disorders last year, which showed an increase of about 24% compared to 2021
While adults in their 50s, 60s, and 70s still account for the largest share of patients, the fastest growth has been recorded among children less than 10 years of age. Teenagers also experienced a notable increase of more than 32% during the same period.
Also read: Obesity-Driven CKM Syndrome A Growing Public Health Threat, Warns American Heart Association
Health experts say that there are factors that are likely driving the surge. One of the biggest contributors is the widespread and rampant use of smartphones, tablets, and other digital devices before bedtime.
Research states that exposure to blue light suppresses the production of melatonin, the hormone that regulates the body's sleep-wake cycle, making it harder for children to fall asleep.
Increased screen time is also replacing physical activity and playtime outdoors, both of which are essential for healthy nighttime sleep.
Academic pressure could also affect children’s sleep. Many children under 10 attend after-school academies called hagwons, spend long hours studying, and have increasingly structured schedules that leave little to no time for adequate rest.
Combined with irregular bedtime and stress, these factors can disrupt normal sleep patterns.
Also read: Chronic Fatigue: More Than Just Lack of Rest
Experts also point to growing levels of stress and anxiety among children. Family pressures, highly competitive educational environments, and lifestyle changes following the COVID-19 pandemic have all been linked to increasingly poor sleep quality in children.
Mental health problems like anxiety can both contribute to and result from chronic sleep disturbances, creating a cycle that becomes difficult to break.
Insomnia remains the most common sleep disorder diagnosed in South Korea. Previous research has shown that the prevalence of diagnosed sleep disorders in the country nearly doubled between 2011 and 2020, highlighting that the current increase among children is part of a broader national trend.
Poor sleep during childhood could lead to poor attention, memory, learning, emotional regulation, and immune function. Children who consistently sleep too little may also face a higher risk of obesity, depression, and behavioral problems later in life.
Sleep specialists stress that parents should establish consistent bedtime routines, reduce evening screen exposure, encourage regular physical activity, and seek medical evaluation if symptoms like prolonged insomnia, loud snoring, or excessive daytime sleepiness continue.
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Young adults who believe vaping is safer than smoking may be in for some surprising news. According to a new study, vape users presented reduced fitness and impaired blood vessel function similar to traditional cigarette smokers.
The research, published in the peer-reviewed journal ERJ Open Research, compared healthy adults aged 18 to 30 and found that both regular vapers and smokers had around 15% lower exercise capacity than people who had never smoked or vaped.
The study involved 75 healthy young adults divided into three groups: non-smokers/non-vapers, cigarette smokers, and regular vapers who had never smoked.
Participants completed an incremental cycling test while researchers measured heart and lung function, oxygen activity, blood lactate levels, and overall vascular health.
Researchers also observed equally poor blood vessel function, reduced breathing efficiency during exercise, and early muscle fatigue in both those who vaped and smoked.
At peak exercise, both smokers and vapers showed significantly lower oxygen uptake and reached exhaustion sooner than non-users.
They also accumulated lactic acid more quickly, leading to greater breathlessness and increased leg discomfort during exercise. Ultrasound scans and blood tests further showed signs of impaired blood vessel function and inflammation.
Dr. Azmy Faisal, senior lecturer in cardiorespiratory physiology at Manchester Metropolitan University and lead author of the study, said, “In active, healthy young adults with normal lungs, both vapes and tobacco smoking led to worsened exercise capacity, shortness of breath, and intense leg fatigue.”
"Like smoking, our research indicates that vaping can lead to harmful changes to the blood vessels, lung efficiency during exercise, and approximately a 15% reduction in fitness compared to those who have never smoked or vaped," Faisal added.
Dr. Stamatoula Tsikrika of the European Respiratory Society commented on the findings, saying the growing popularity of vaping among young people who have never smoked is becoming an increasing public health concern.
Also read: How Smoking, Alcohol, And Vaping Are Quietly Hurting Women’s Fertility
"More and more young people who have never smoked are using vapes," Tsikrika said. "As the popularity of vaping continues to rise, so too do concerns that it is becoming normalised behaviour, functioning as a gateway to nicotine addiction and introducing serious health risks."
She noted that although e-cigarettes may contain fewer cancer-causing substances than conventional cigarettes, they can still lead to significant genetic changes.
"Vapes may contain lower levels of cancer-causing substances, but they can still trigger genetic changes such as DNA damage and inflammation, which are linked to increased lung cancer risk," Tsikrika said. "For people who have never smoked and are therefore not using vapes as a cessation method, the health consequences of vaping are becoming harder for policymakers and the tobacco industry to justify."
Also read: Friends Can Have A Big Impact On Vaping Habits, Study Suggests
The researchers, however, caution that the study does not suggest that vaping is equally harmful as smoking in every respect.
Traditional cigarettes still strongly remain linked to major disorders like cancer, chronic obstructive pulmonary disease (COPD), and many other life-threatening illnesses.
But the new study indicates that when it comes to cardiovascular fitness, breathing efficiency, lung function and blood vessel health in young adults, vaping may offer far less protection.
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