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Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
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Eli Lilly has made its latest move to look beyond the blockbuster GLP-1 market by agreeing to acquire biotech company Merida Biosciences for up to $2.875 billion in cash.
The deal will give Lilly access to Merida's experimental treatments for autoimmune and allergic diseases, including a potential drug for Graves' disease and thyroid eye disease. The transaction is expected to be completed in the fourth quarter of 2026, subject to regulatory approvals and other conditions.
The acquisition is another sign that Lilly is trying to diversify its pipeline beyond the obesity and diabetes medicines that have driven its recent growth. Lilly's spending on similar deals in 2026 that signals the company is looking to to expand beyond its successful hold on GLP-1 markets.
Merida's lead programme, MER511, is currently in Phase 1 development for Graves' disease and thyroid eye disease (TED). The experimental treatment uses Merida's antibody-engineering platform to selectively remove pathogenic autoantibodies, the antibodies responsible for driving certain autoimmune diseases.
The idea is different from conventional immune-suppressing medicines, which dampen immune activity broadly. Initial Phase 1 data showed that MER511 substantially reduced thyroid-stimulating antibodies associated with Graves' disease and TED, while showing a favourable initial safety profile.
Francisco Ramírez-Valle, Lilly's senior vice president of immunology research and early clinical development, said, “We're building our pipeline around therapies that meaningfully change the course of disease, not just its downstream effects.”
He added that Merida's lead programme is designed to selectively and directly target the antibodies driving Graves' disease and thyroid eye disease.
Also read: Eli Lilly’s Foundayo Launched In UK: Is the GLP-1 Pill Better Than Wegovy, Mounjaro?
In thyroid eye disease, inflammation can cause eye bulging, pain, double vision and, in severe cases, vision impairment.
Lilly's interest is specifically in Merida's approach is its attempt to target the disease-causing antibodies themselves, rather than suppressing the immune system more broadly.
Merida CEO Adam Townsend said, “Merida was founded to fundamentally change how autoimmune and allergic diseases are treated, by targeting the antibodies driving them directly, rather than suppressing the immune system broadly.”
That could potentially offer a more precise way of treating diseases in which specific autoantibodies are driving the damage.
Also read: Wegovy Is The Go-To Weightloss Drug Choice For Most US Teens
The acquisition isn't only about Graves' disease. Merida's pipeline includes MER769, an experimental programme being developed for food allergy, asthma, chronic spontaneous urticaria and other allergic diseases.
The company also has earlier-stage programmes targeting kidney diseases and other conditions mediated by immunity.
This gives Lilly a potential base across a much broader range of immune-mediated diseases. The company that became synonymous with Mounjaro and Zepbound is trying to build a pharmaceutical portfolio that does not cash in entirely on the GLP-1 boom.
MER511 is still only in Phase 1, meaning its safety and preliminary biological activity are being evaluated in early clinical testing. The promising initial data do not yet establish whether the drug will ultimately work in larger patient populations or receive regulatory approval.
The $2.88-billion deal is therefore not Lilly buying an already-proven autoimmune medicine. It is buying a platform and the potential for an entirely new class of treatments.
As Townsend put it, “Joining Lilly gives our science the resources and commitment to realize its potential for patients with immune-mediated conditions.”
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The NHS in England today announced that 100 pharmacies will offer free cholesterol check-ups beginning this autumn.
The initiative is part of an NHS drive to reduce heart disease and stroke deaths by a quarter over the next decade. It will include free finger-prick blood tests for cholesterol on the high street for the first time.
People aged 40 to 84 who are not pregnant and have not had a blood test in the past year will be eligible to walk in and get tested.
Eligible people will also be offered a blood pressure check as part of a clinical consultation with a pharmacist prescriber.
The NHS pilot will run until spring 2027.
Blood will be taken from a person’s fingertip using a lancet — a small, sharp medical tool used to prick the skin — and analyzed immediately. A pharmacist prescriber can then provide lifestyle advice and determine whether any treatment, such as statins, may be needed.
Patients will receive a copy of their results by email. They will also be offered a blood pressure check as part of a clinical consultation with a pharmacist prescriber.
The national rollout follows a successful smaller pilot in north London, which tested 2,493 patients at 61 community pharmacies between January 2025 and March 2026.
Nearly one in five patients were found to be suitable for pharmacological intervention, and 88 people started taking statins.
David Webb, the chief pharmaceutical officer for England, said pharmacies could be a vital first line of defense against serious illness.
He said: “By making it easier for people to get a quick and convenient cholesterol health check on their local high street, we can spot ticking timebombs earlier, helping people take action, and prevent heart attacks and strokes before they happen.
“This is the latest in a series of initiatives involving pharmacies in delivering care previously only offered in GP surgeries as part of the 10-year health plan to bring care closer to where people live.”
In the first phase of the national rollout, about 100 NHS pharmacies across England will begin offering the checks from this autumn.
Dr Rani Khatib, NHS England’s national specialty adviser for cardiovascular disease prevention, said everyone should strive to be aware of the most common risk factors for heart disease, including high cholesterol and blood pressure, and “know their numbers”.
“This initiative will help people manage their risk factors earlier and reduce their risk of having heart attacks or strokes,” he said.
Alison McGovern, a health minister, said it was “exactly the type of innovation” she wanted to see across the NHS.
“We’re making it easier for people to spot potential problems earlier and take action to protect their health,” she said.
“Early detection can help prevent serious conditions such as heart attacks and strokes, helping people stay healthier for longer while reducing pressure on NHS services.”
Too much LDL (“bad”) cholesterol in the blood can build up inside artery walls. Over time, these fatty deposits — called plaque or atheroma — can make arteries narrower and restrict blood flow, according to the NHS.
High cholesterol usually causes no symptoms, which is why testing is important. Cholesterol can be reduced through healthier eating and regular exercise and, for people at sufficient risk, medicines such as statins.
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Amid declining childhood vaccination rates and an anti-vaccine push from the government, the US is reporting a significant uptick in measles cases in three more states.
The states include Pennsylvania, Wisconsin, and Georgia. Pennsylvania has also reported two deaths, including an Amish newborn, marking 2026’s first measles-related deaths in the country.
Two unvaccinated individuals, including a newborn infant, died, marking the first measles-associated deaths in the state in 35 years.
Also read: Measles: Infant Among Two Unvaccinated Deaths Reported In US
According to the Centers for Disease Control and Prevention, 2,903 confirmed cases had been reported nationwide as of August 27, threatening the US measles-elimination status held since 2000.
About 94% of cases are among unvaccinated people, and children under 5 account for 19% of cases.
This is the highest number of cases reported since the major resurgence between 1989 and 1991, when 55,000 infections and 123 deaths were recorded.
In comparison, for the full year 2025, the country reported 2,289 cases and three deaths.
While two doses of the MMR vaccine are key to preventing measles, the highly contagious virus, the first MMR dose is recommended at 12 to 15 months, followed by a second dose at 4 to 6 years.
The anti-vaccine stance promoted by the Trump-led US government and HHS Secretary RFK Jr. comes as cases are spiraling. More recently, Trump also announced a split of the MMR vaccine.
Measles is a serious and highly contagious illness that can be particularly dangerous for babies and young children. The best way to prevent measles is to get vaccinated.
The measles, mumps and rubella (MMR) vaccine is a safe and effective way to protect yourself and others from this dangerous disease.
Measles is more than just a simple rash and can lead to severe health problems and, in some cases, death.
The first signs of measles often mimic a common cold. These initial symptoms include a high fever that can reach over 104°F, a persistent cough, a runny nose, and red, watery eyes.
These symptoms can be misleading, but their combination is a key indicator of the onset of measles.
A distinctive sign of measles is the appearance of tiny white spots, called Koplik spots, inside the mouth. These spots typically develop two to three days after the initial symptoms begin.
Their presence is an important diagnostic clue, often appearing before the characteristic measles rash.
A rash appears three to five days after the initial symptoms. It usually starts as flat red spots on the face, near the hairline, and then spreads downward to the neck, trunk, arms, legs and feet.
The spots can sometimes be slightly raised and may merge. When the rash appears, the fever may also increase significantly.
While measles can be serious for anyone, certain groups are at a higher risk of developing complications. These include:
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