Can Weight Loss Drugs Curb Alcoholism? See What Study Says

Updated Feb 13, 2025 | 09:02 AM IST

SummaryResearchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
Can weightloss drug curb alcoholism?

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Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.

What Do Studies Say?

The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.

The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.

The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.

The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.

How Was The Study Conducted?

The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.

Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."

Why Does It Work So Well Against Alcoholism?

The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.

However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.

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Medical Miracle: World First Frozen Testicular Implant Gives ‘Infertile’ UK Man Hope of Fatherhood

Updated May 5, 2026 | 11:01 PM IST

SummaryAt the age of 9, Nathan Crawford underwent radiotherapy and chemotherapy to shrink his tumor. Before these, his surgeons, in a keyhole surgery, removed and froze a wedge of testicular tissue. Now at the age of 27, the reimplanted tissue has produced sperm, raising hopes for his fatherhood.
Medical Miracle: World First Frozen Testicular Implant Gives ‘Infertile’ UK Man Hope of Fatherhood

Credit: iStock

Nathan Crawford from the UK was just 9-years-old when his testicular tissue was frozen, before undergoing chemotherapy for his brain tumor.

About 16 years later, the cryopreserved immature testicular tissue was reintroduced into his body, which triggered sperm cell production and restored his fertility, according to researchers from the Vrije Universiteit Brussel.

“This is an important step in further scientific research to preserve the fertility of children with cancer or other blood diseases for the future. While the procedure is specifically designed to restore fertility, we cannot at this time guarantee that it will be successful or that patients can go on to have children. This treatment offers lots of perspectives for these young adults. They now have options that they did not have until recently,” said Dr Veerle Vloeberghs, part of the novel trial and staff member at Brussels IVF.

What Had Happened To Nathan

Nathan, now 27-years-old, had a type of tumor called a glioma, which develops from the glial cells that support the nerve cells of the brain, The Guardian reported. The tumor was so close to vital brain tissue that surgeons were unable to remove it without causing serious damage to important brain functions.

He underwent radiotherapy and chemotherapy to shrink his tumor, before which surgeons at the John Radcliffe hospital in Oxford in a keyhole surgery removed and froze a wedge of testicular tissue, with the aim that it is one day re-implanted into Nathan.

How Is The Testicular Tissue Preserved?

While Chemotherapy and radiation therapy are lifesaving they can destroy testicular stem cells, the precursors of sperm cells in boys who undergo radical treatments before starting puberty. As it can affect their fertility, preventively removing and freezing testicular tissue is an option pioneered by UZ Brussel.

In 2002, UZ Brussel became the first hospital worldwide to initiate a clinical fertility preservation program for young boys suffering from cancer or diseases of the blood, bone marrow or lymph nodes.

Since then, the hospital has frozen testicular tissue fragments of 141 boys.

The tissue is preserved in liquid nitrogen at -196°C.

Prepubescent boys do not yet produce sperm cells. The removed tissue contains stem cells that would normally produce sperm after starting puberty.

"While the procedure is specifically designed to restore fertility, we cannot at this time guarantee that it will be successful or that patients can go on to have children,” Dr Vloeberghs said.

How Was The Testicular tissue Implanted

The Guardian reported that in 2025, four tissue fragments were grafted back into the remaining testicle and four under the skin of the scrotum.

After a year inside the body, the grafts were removed and analysed in the laboratory. The results are published in a preprint paper, which is yet to be peer reviewed.

Two of the grafts from inside the testicle had produced mature sperm, which was collected and frozen.

Because the tissue fragments are not directly connected to the sperm duct, the researchers do not expect sperm cells to naturally find their way into the semen.

“This is a huge finding,” Prof Ellen Goossens, of the Vrije Universiteit Brussel, who led the trial was quoted as saying. “Many more people will have hope that they can have biological children. It’s great to see for the patients for whom we already have tissue banked.”

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Does Influenza D Virus Really Pose A Risk To Humans? Expert Explains

Updated May 5, 2026 | 08:00 PM IST

SummaryUS ​CDC’s January 2026 report stated that “influenza D has shown to have considerable potential for causing future human epidemics, but diagnostics and surveillance for the viruses are lacking”.
Does Influenza D Virus Really Pose A Risk To Humans? Expert Explains

Credit: AI generated image

A new research paper published in the PNAS Journal triggered concerns over the potential risk of influenza D spilling over into humans.

Although primarily found in livestock such as cattle and swine, this virus has been increasingly studied due to evidence of exposure among agricultural workers.

A key concern raised was that the influenza D virus triggers a relatively weak early immune response in human respiratory cells.

However, to understand whether it is just a hype or a real concern, HealthandMe spoke to Dr. Rajeev Jayadevan, Ex-President of IMA Cochin and Convener of the Research Cell, Kerala.

“So far, this virus has not been a major cause of respiratory disease in man, unlike other types of Influenza viruses like H1N1 and H3N2 of the Influenza A family. It is true that studies have demonstrated antibodies against this virus among cattle farmers, which is consistent with its ability to infect species other than cattle,” Dr. Jayadevan said.

He noted that the virus may not be an “imminent threat” to humankind as feared.

“So far, the signals are that this virus remains primarily a cattle pathogen, which doesn’t pose an imminent threat to man, unlike other types of influenza viruses”.

What is the Influenza D Virus?

Influenza D is one of four types of influenza viruses and belongs to the Orthomyxoviridae family. Unlike the more familiar influenza A and B viruses that cause seasonal flu in humans, influenza D has primarily been detected in animals, particularly cattle and pigs.

According to the US CDC, the virus was first identified in 2011. It has since been found across multiple species, including livestock and wildlife, including camels, deer, giraffes, kangaroos, llamas, wallabies, and wildebeests.

It is not currently known to cause illness in humans, but has had a spill over in different animal species — more recently in poultry.

CDC’s January 2026 report stated that “influenza D has shown to have considerable potential for causing future human epidemics, but diagnostics and surveillance for the viruses are lacking”.

Also read: Can A Common Cold Virus Save You From Cancer? New Study Claims So

What Did The PNAS Study find?

Researchers investigated multiple influenza D virus isolates collected from livestock between 2011 and 2020 to assess their ability to infect human airway systems.

The paper demonstrated that the virus is capable of infecting human respiratory cells and was also adept at switching off the interferon-based ‘alarm systems’ of the cell.

This means that the virus may spread silently and efficiently, but without causing significant symptoms, Dr. Jayadevan said.

Importantly, the findings suggest that only small genetic changes might be needed for influenza D virus to achieve more sustained transmission in humans, although this has not yet been observed.

Read More: Hantavirus Outbreak: WHO Flags 6 Suspected Cases; How The Rare Rodent-Borne Virus Spreads

H5N1 Bird Flu: A More Deadly Threat

Dr. Jayadevan told HealthandMe that a bigger concern for humans besides the commonly circulating human Influenza A and B viruses is the avian influenza (bird flu) virus H5N1.

H5N1 spreads among birds and carries a very high death rate whenever it infects humans.

“Fortunately, this bird flu virus isn’t able to easily spread from person to person, but ongoing mutations could potentially change that,” the expert said.

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Donald Trump’s Weekend Dental Appointment Triggers Fresh Health Concerns

Updated May 6, 2026 | 12:00 AM IST

SummaryConcern for the health of the President, set to turn 80 next month, was further fueled by a social media post by Nancy Mace, representative for South Carolina, where she wrote, “Pray for President Trump.”
Donald Trump’s Weekend Dental Appointment Triggers Fresh Health Concerns

Credit: Reuters

US President Donald Trump’s visit to a dentist in Florida over the weekend has reignited discussions about his health.

While past presidents have opted for the White House's on-site clinic, Trump went for a local dentist instead, a choice he made previously in January.

Trump's Dentist Visit Triggers Concern

Concern for the health of the President, set to turn 80 next month, was further fueled by a social media post by Nancy Mace, representative for South Carolina, where she wrote, “Pray for President Trump.”

Her sudden post came after the news that Trump had left his Jupiter golf club in Florida for a dentist appointment.

The White House, in a press pool reported: "President Trump is going to a scheduled dental appointment at his local dentist in Florida", The NewsWeek reported.

Republican strategist Cheri Jacobus also wondered about the timing of the President's appointment and what "caused him to suddenly leave his golf course?" Jacobus also questioned the White House for hiding Trump's health status.

However, there has been no statement from Trump’s office, family, or verified government channels confirming any medical emergency or surgical procedure as of now.

Also read: Donald Trump’s Discolored Left Hand Triggers Health Speculation: Expert Explains

Trump's Health Issues

It is not the first time that Trump has been the subject of numerous health-related scrutiny — ranging from his mental state to visible bruising around his hands.

While there remains no official medical update on the discoloration in Trump's hand, Dr. Amit Prakash Singh, Consultant - Internal Medicine at the CK Birla Hospital, Delhi, told HealthandMe that there are possible underlying causes that can result in hand discoloration. He noted that the condition may be due to:

  • Bruising (bleeding under the skin)
  • Low oxygen or poor circulation
  • Swelling (fluid buildup in tissues)
  • Infection or inflammation

Media reports also expressed concern over Trump’s swollen ankles, which were photographed again during his weekend trip to Florida.

On Saturday, Trump was photographed with his son, Donald Trump Jr. His swollen ankles visible in the photos are likely the result of chronic venous insufficiency (CVI), which he was diagnosed with last July.

"CVI damages those valves, causing blood to pool in your legs. This increases pressure in your leg veins and causes symptoms like swelling and ulcers," according to the Cleveland Clinic.

In January, Trump told the Wall Street Journal that he'd tried using compression socks to help treat the issue but stopped because he "didn't like them."

Trump has also made some unusual medical choices in the past. Most notable is his use of aspirin. Trump takes 325 milligrams of aspirin every day, according to the Daily Beast. That's four times the doctor-recommended dosage.

Read More: Why Does Donald Trump Stand Like That? The Age Factor Of Poor Posture Explained

Trumps' Dipping Image Among Americans

Meanwhile, nearly 60 per cent of Americans are questioning whether or not Trump is healthy enough to serve in the Oval Office, according to a Washington Post-ABC News-Ipsos poll.

In addition to dissatisfaction over Trump’s leadership on the Iran war, economy, and inflation, a growing share of Americans are also questioning the President’s mental acuity for the position.

Nearly 6 in 10 say he does not have the mental sharpness, while 55 percent say he is not in good enough physical health to serve effectively.

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