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Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
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The Union Ministry of Health and Family Welfare has proposed mandatory CCTV surveillance at medical stores as an additional regulatory safeguard for prescription drugs.
The move, proposed under amendments to the Drugs Rules, 1945, through Draft Gazette Notification G.S.R. 791 (E), aims to strengthen regulatory oversight of Schedule H, H1 and X drugs.
Once implemented, it will help strengthen monitoring of the sale and distribution of these drugs and curb their unauthorized access and sale without valid prescriptions.
The proposed CCTV surveillance mechanism will also enhance transparency and accountability across the pharmaceutical supply chain, strengthening safeguards for public health. The draft proposal is now open to public objections and suggestions before it is finalized.
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Schedule H: Prescription-only medicines, including many blood pressure, diabetes and anti-infective drugs. They must carry the Rx symbol and cannot be sold without a prescription.
Schedule H1: A stricter category covering certain antibiotics, anti-tuberculosis drugs and sedatives. These medicines carry a red-boxed Rx warning and require medical advice.
Schedule X: The strictest category, covering certain high-risk narcotic and psychotropic drugs such as morphine, amphetamines and strong barbiturates. Their sale requires a specific government licence in addition to a standard retail drug licence.
India is seeing concerns over spurious and fake drugs, with chemists being the major point of contact for medicines for a majority of people.
A recent nationwide survey by LocalCircles, a community social media platform, showed that 64% of consumers said chemists never or rarely ask for a doctor's prescription, while only 31% mostly got a qualified pharmacist at their chemist.
Only 15% of those surveyed said the chemist mostly or always refused to sell medicines without a prescription.
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The survey also found:
In a recent shocking case, investigators in Bengaluru seized large counterfeit cancer medicines, life-saving drugs and injections used in intensive care units (ICUs) that were being supplied to hospitals, clinics and medical stores.
According to investigators, the medicines may have been supplied to more than 90 hospitals and clinics in Bengaluru.
A public interest litigation (PIL) has also been filed in the Supreme Court seeking a comprehensive national framework to check the manufacture and sale of counterfeit and adulterated medicines, including vaccines and cough syrups.
Data placed before Parliament shows that 1,41,322 drug samples were tested in 2025-26, the highest in five years. Of these, 3,012 were found to be Not of Standard Quality (NSQ) and 283 were found to be spurious or adulterated. A total of 779 prosecution cases were filed during the year, while 3,599 cases were filed over five years.
The Central Drugs Standard Control Organisation (CDSCO) has also continued issuing monthly drug alerts through 2026, flagging 240 NSQ samples in January, 194 in February along with four spurious drugs, 168 in March, 157 in May and 159 in June.
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Pennsylvania’s measles outbreak has crossed 700 cases, with the state reporting 731 cases, four measles-associated deaths and 141 hospitalizations as of September 16. The four deaths are the first in 35 years in the State and speaks volumes about the severity of the outbreak.
The state has also reported measles cases among vaccinated people, although these account for less than 1% of total cases.
The Pennsylvania Department of Health has requested emergency assistance from the US Centers for Disease Control and Prevention (CDC), known as an Epi-Aid, according to a letter reviewed by Reuters.
However, the request is tied to a dispute over the CDC’s decision not to publicly recognize the four measles-associated deaths.
“The CDC’s choice not to publicly recognize the deaths undermines our response,” Pennsylvania Health Secretary Debra Bogen wrote to CDC Director Erica Schwartz.
She said the state would rescind its Epi-Aid request if the CDC could not “transparently and accurately communicate information” about the deaths.
Also read: Bill Gates Says Vaccine Hesitancy Could Make Ending Measles Impossible
The dispute has also triggered a political clash between Pennsylvania Gov. Josh Shapiro and US Health Secretary Robert F. Kennedy Jr.
Shapiro accused Kennedy of fueling vaccine skepticism, while Kennedy said Shapiro had declined federal assistance. Kennedy has also said the CDC’s MMR recommendation remains unchanged.
“CDC’s MMR recommendation remains unchanged. I have repeatedly stated that MMR vaccination is the most effective way to prevent measles infection,” he said.
Shapiro said Pennsylvania would accept federal assistance but called on Kennedy and the CDC to recognize the four deaths.
The CDC is now using data from the National Center for Health Statistics (NCHS) to track measles deaths, according to a September 4 agency note.
Previously, it used the National Notifiable Diseases Surveillance System (NNDSS) to report such data.
“CDC will report measles deaths if and when the National Center for Health Statistics reports measles as the underlying cause of death,” said Emily Hilliard, a US Department of Health and Human Services spokesperson.
The CDC’s 2026 tally currently shows no measles deaths because NCHS does not yet have records listing measles as the underlying cause.
Read More: 18-Year-Old Dies From Rare Measles Brain Complication As Pennsylvania Death Toll Hits 4
Measles can cause complications including pneumonia and brain swelling. Nearly 20% of people who contract measles are hospitalized, while death, though rare, occurs in one to three patients per 1,000 cases.
The virus spreads through respiratory droplets and can remain infectious in the air and on surfaces for up to two hours.
Symptoms include fever, cough, runny nose and red, watery eyes, followed by a rash that typically begins on the head and spreads downward. Symptoms can appear 7 to 21 days after exposure.
The best protection against measles is vaccination. Two doses of the MMR vaccine provide 97% protection against measles, according to the Pennsylvania Department of Health.
People with two documented doses generally do not need another. Those with only one dose or without vaccination records should speak with a healthcare provider or pharmacist.
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UK’s National Institute for Health and Care Excellence (NICE) has advised healthcare professionals to look for signs of obsessive-compulsive disorder (OCD) and body dysmorphic disorder (BDD) in people seeking cosmetic procedures such as Botox and fillers.
The recommendation is part of a draft guideline aimed at earlier identification of the two conditions, which can remain undiagnosed for years because people may hide symptoms due to shame or embarrassment. In addition, the cosmetic industry is vastly unregulated, increasing potential health risk.
“People with obsessive-compulsive disorder (OCD) and body dysmorphic disorder (BDD) could be identified earlier and offered more appropriate treatment,” said the draft NICE guidance published today.
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NICE’s new draft recommends considering assessment for OCD or BDD among people with depression, anxiety, autism or ADHD, as well as those seeking cosmetic procedures.
The committee said symptoms can be overlooked or attributed to other conditions, delaying diagnosis and treatment.
"People with obsessive-compulsive disorder and body dysmorphic disorder can experience symptoms for a long time before they receive the right diagnosis and support. These conditions are often misunderstood, and many people find them difficult to talk about because of embarrassment, shame or fear of being judged,” Eric Power, interim director of the Centre for Guidelines at NICE, said.
Healthcare professionals providing cosmetic treatments, including surgeons, dentists and dermatologists, would be advised to ask structured questions about appearance-related concerns and document their findings.
If responses suggest possible BDD, NICE recommends specialist assessment rather than proceeding with the cosmetic procedure at that stage.
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The committee noted that cosmetic procedures rarely improve the underlying condition and may sometimes worsen symptoms.
A 2024 systematic review and meta-analysis estimated that 18.6% of people attending aesthetic and reconstructive plastic surgery services had clinically significant BDD symptoms, compared with around 2% of adults in the wider population.
"Our draft recommendations aim to help healthcare professionals recognize symptoms earlier, ask the right questions and support people to access appropriate treatment sooner," Power said.
"Earlier identification can help ensure people receive care that reflects their needs, preferences and circumstances, rather than waiting until symptoms become more severe or reach crisis point," he added.
The draft guideline also proposes a personalized “matched care” approach to OCD treatment, with interventions based on a person’s clinical needs, treatment history and preferences rather than a fixed sequence.
For children and young people with OCD, the draft recommends family-based cognitive behavioral therapy for many patients.
OCD affects an estimated 1.2% of the population. It involves unwanted, distressing thoughts, images, urges or doubts, often followed by repetitive behaviors or mental rituals such as checking, washing, counting or seeking reassurance.
BDD involves excessive preoccupation with perceived flaws in appearance, which can cause significant distress and interfere with daily life. Research suggests it affects around 2% of adults.
The consultation on the draft NICE guideline is open until October 21, 2026.
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