Credits: Canva
Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
Credit: AI
The Ludhiana health department has increased surveillance and prevention efforts after a bunch of new cases of malaria and dengue were reported in the district.
Health officials have stepped up inspections, awareness campaigns, and anti-larval operations, urging residents to eliminate stagnant water and seek medical attention at the first sign of fever.
Also read: Monsoon Playbook for Parents: Common Home Mistakes That Increase Infection Risk in Children
According to recent reports, extensive door-to-door inspections are being carried out across residential areas, schools, and public spaces to identify mosquito breeding sites.
During these inspections, dengue mosquito larvae were found in several homes, prompting authorities to issue notices to property owners and instruct them to immediately remove stagnant water.
The department said these inspections are part of an ongoing strategy to reduce mosquito breeding before cases increase further during peak monsoon season.
Also read: From Heavy Floods To Extremely Humid, How Mumbai's Extreme Weather Can Impact Your Health?
The move comes after Ludhiana experienced a difficult mosquito-borne disease season last year. Official data showed the district recorded 128 malaria cases, including one death, and 538 dengue cases with one fatality, making early intervention a priority this year.
Health authorities say that increasing temperatures combined with intermittent rainfall have created favourable conditions for mosquitoes to multiply rapidly, making community participation essential in preventing another surge.
Officials are stressing that dengue and malaria are transmitted by different mosquitoes and require slightly different prevention strategies.
Dengue is spread by the Aedes mosquito, which breeds in clean, stagnant water found in coolers, flower pots, buckets, discarded tyres, and rooftop water tanks. These mosquitoes are most active during the daytime.
Malaria, on the other hand, is transmitted by Anopheles mosquitoes, which usually bite from dusk until dawn.
Eliminating breeding sites remains the most effective way to reduce the spread of both diseases.
Doctors advise residents to watch for symptoms such as high fever, severe headache, body aches, joint pain, chills, nausea, vomiting, excessive fatigue, or skin rashes. Anyone experiencing persistent fever should avoid self-medication and seek medical care promptly.
Early diagnosis helps prevent complications, particularly in severe dengue cases where warning signs such as abdominal pain, persistent vomiting, bleeding gums, or difficulty breathing require immediate hospitalization.
Health experts recommend practising a combination of personal protection and environmental control:
Public health officials say that preventing mosquito breeding at the household level remains the strongest defence against dengue and malaria. While health officials and their teams continue surveillance for containment, they emphasize that success depends on active community participation in keeping homes and neighbourhoods free of stagnant water.
Credit: AI
The transport of Ebola victims' bodies across provinces in the Democratic Republic of Congo (DRC) is emerging as one of the major causes of the country's rapidly expanding Ebola outbreak. The United Nations' International Organization for Migration recently issued a warning regarding the same.
According to the IOM, the movement of deceased Ebola patients from the place of death to their home communities for traditional funeral ceremonies is increasing the risk of spreading the deadly virus into previously unaffected areas. The warning comes as eastern Congo battles its largest Ebola outbreak in years, caused by the Bundibugyo strain, for which there is currently no vaccine.
As of July 14, more than 2,000 Ebola cases and over 700 deaths had been reported in Congo and neighboring Uganda.
Unlike other infectious diseases, Ebola remains highly contagious even after a patient has died. The virus can be transmitted through direct contact with bodily fluids during funeral rituals, including washing, dressing, or touching the body.
In many parts of the country, families prefer to bury loved ones in their ancestral villages, often transporting bodies over long distances, which can unintentionally increase Ebola transmission.
The IOM stated that nearly two-thirds of Ebola-related deaths have occurred outside hospitals, making it difficult for trained burial teams to manage bodies safely before they are handed over to families.
"If we don't really manage the dead bodies well, if we don't engage the community. Then it means there will be more spread within the community," said Andrew Mbala from IOM.
According to Reuters, the agency said that at least 105 instances where bodies were transported between districts, including one case that was linked to new Ebola infections in Congo's Tshopo province.
The IOM said the current outbreak has grown by nearly 70% within two weeks, with more than 40 new cases being reported daily, highlighting how quickly the virus is spreading.
The agency stressed that safe and dignified burial practices, developed in partnership with local communities, remain one of the most effective tools for interrupting Ebola transmission.
"Ebola remains highly infectious after death, making funeral practices a critical component of outbreak control," the IOM said in its latest update.
Health officials say the outbreak response continues to face significant obstacles beyond the virus itself.
Community resistance, misinformation, mistrust, insecurity, and attacks on healthcare workers have hampered contact tracing, safe burials, and treatment efforts.
According to the IOM, around one in five people identified as contacts of Ebola patients cannot currently be traced, making it increasingly difficult to contain transmission chains.
The outbreak, first officially recognized in May, has already spread across multiple provinces in eastern Congo.
Public health experts fear that continued movement of infected bodies, combined with undetected community transmission, could allow Ebola to reach additional regions if containment measures are not strengthened.
Credit: Instagram
BBC presenter Lauren Laverne has revealed that she has been diagnosed with smoldering myeloma — a blood and bone marrow disorder that currently has no cure.
The chronic condition was discovered by her doctor nearly two years after Laverne recovered from cancer in August 2024. Laverne has not publicly disclosed the exact type of cancer she was treated for.
Taking to Instagram, the 48-year-old TV presenter shared her health update, telling followers that she has been diagnosed with a "chronic condition."
"I’ve been diagnosed with something called smoldering myeloma (yes, that is a weird name and no, I’d never heard of it either)," she wrote. "It’s an asymptomatic blood and bone marrow disorder that in some people can develop into blood cancer."
Stating that her risk "is pretty low," Laverne explained that she does not need treatment at the moment. However, she noted that there is currently no cure and that her immune system is "a bit compromised."
She also clarified that the diagnosis "has nothing to do with my previous illness or my recent surgery, it’s just one of those things."
Also read: Cancer Kills Over 26,000 Daily; Cases to Hit 35 Million by 2050, Says WHO Report
Because of the diagnosis, Laverne said she will be closely monitored with blood tests, MRIs, and bone marrow biopsies, which she joked she has "recently discovered are even less fun than they sound."
She revealed that the condition was identified after her GP noticed she had "persistently low iron levels."
"I've had some difficult experiences in the last eight years, but I have learned more from them than some people do in a lifetime and that is helping me right now. I am so grateful for that," she said.
Laverne also thanked her family, friends, doctors, consultants, nurses, and her team at BBC Radio 6 Music. Many of her fellow TV and radio personalities shared messages of support following her announcement.
According to Blood Cancer UK, "Smoldering myeloma is the name given to myeloma that has no symptoms or signs of damage to your organs."
Myeloma is a type of blood cancer that affects plasma cells in the bone marrow. Smoldering myeloma is an inactive, early form of the disease that does not cause symptoms or organ damage.
The charity says that people with smoldering myeloma usually do not need treatment right away. Instead, they undergo regular checkups so doctors can monitor whether the condition is progressing to active myeloma.
Read More: Attention Brits! UK Warns Travelers About Deadly Methanol Poisoning Abroad
According to the International Myeloma Foundation, smoldering multiple myeloma (SMM) is an asymptomatic precursor stage of multiple myeloma (MM). While both conditions involve abnormal plasma cells, people with SMM have no symptoms or end-organ damage and are typically monitored rather than treated.
The disease generally progresses through precursor stages:
People with smoldering myeloma are generally managed through active surveillance, with regular blood tests, imaging scans, and other monitoring to detect any signs that the disease is becoming active. Active monitoring is considered a safe approach for most patients.
Doctors may recommend treatment in certain situations, including:
© 2024 Bennett, Coleman & Company Limited