Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.

What Do Studies Say?

The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.

The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.

The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.

The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.

How Was The Study Conducted?

The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.

Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."

Why Does It Work So Well Against Alcoholism?

The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.

However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.

A team of Australian scientists has developed cyborg cockroaches for medical missions. Researchers from the University of Queensland fitted Giant Burrowing Cockroaches with a removable navigation system that enables them to be remotely piloted through complex terrain and rubble.

The cockroaches are equipped with cameras and miniature medical injectors to deliver supervised emergency care to people trapped in collapsed buildings or caves.

What's The Purpose?

Called ‘Paraborgs’, the cyborg insects go beyond searching for survivors to actively assisting them. In the paper, published in Advanced Science, the researchers said the long-term vision is to deploy swarms of specialized cyborg insects at disaster sites, with each performing a complementary role.

“The vision is not to replace first responders, but to give them another way to see, reach and potentially help people when direct access is impossible,” said Dr Vo-Doan from the UQ Biorobotics Lab.

Director of the UNSW Medical Robotics Lab Associate Professor Thanh Nho Do said the Paraborg technology could extend the reach of emergency medicine.

“From a biomedical perspective, the opportunity is to bring treatment to a patient when the patient cannot yet be brought to treatment,” Associate Professor Do said.

“The long-term goal is targeted, human-supervised intervention in places conventional medical technologies cannot access.”

Why Cockroaches?

Dr Vo-Doan said the research demonstrates how cyborg technology can be adapted across different insect platforms.

“Rather than building one robot to do everything, we can harness the natural strengths of different insects and equip them for different missions,” Dr Vo-Doan said.

The larger cockroaches provide greater capacity to carry specialized rescue and medical equipment.

The cockroaches, like the team’s previous cyborg insect models, are anaesthetized during electrode and microchip fitting. They live for as long as other cockroaches once the harnesses are removed.

What About Cyborg Beetles?

The team has previously demonstrated cyborg beetles capable of controlled climbing. They have shown they can remotely guide the movement of common darkling beetles using a video game controller.

The beetles are fitted with removable microchip backpacks that use electrodes to stimulate the insect's antenna or hardened forewings.

The programmable controls allow for precise directional guidance without affecting the lifespan of the beetle.

How Can The Cyborg Cockroaches Aid In Rescue?

Superintendent Tim Hassiotis, Manager Natural Disaster and Humanitarian at Fire and Rescue NSW, said the technology could extend the reach of rescue teams.

“If cyborg insects can safely enter spaces we can’t, locate casualties and ultimately help deliver emergency care, they could become another valuable tool in the future of urban search and rescue,” Superintendent Hassiotis said.

What Could The Future Hold?

Dr Vo-Doan said the longer-term vision was to deploy swarms of specialized cyborg insects, with individuals performing complementary roles.

“Some could carry cameras and environmental sensors, while others could carry specialized emergency or medical equipment,” he said.

“Hopefully, within the next 5 to 10 years, we could see cyborg insect rescue teams deployed to help people in real emergencies, provided we have the resources to accelerate the research and field testing.”

A North Carolina teen is reportedly critically ill after being infected with a rare “brain-eating” amoeba called Naegleria fowleri, according to health officials.

The case comes barely a week after an 8-year-old Louisiana girl died after contracting the infection.

North Carolina Teen Critically Ill

The North Carolina Department of Health and Human Services announced on August 27 that a teen resident had been infected with the rare amoeba, which is commonly found in freshwater. The teen is critically ill and receiving medical care.

The department said it is not releasing further information to protect the family’s privacy. The source of the infection is under investigation.

“While these infections are very rare, this is an important reminder that this amoeba is present in our state and across the US,” North Carolina State Epidemiologist Dr. Zack Moore said in a statement.

What Happened To The Louisiana Girl?

Eight-year-old Lillian Smart of Ruston died on August 22, just one day after her eighth birthday. She had been hospitalised since August 15 after developing the infection, which was believed to have been acquired while swimming in Lake Claiborne.

The Louisiana Department of Health confirmed the case on August 19 but did not publicly identify the child.

One of the biggest challenges is the speed at which the infection progresses. According to recent CDC data cited in coverage of the Louisiana case, 173 Naegleria fowleri infections were documented in the US between 1937 and 2025, with only four known survivors. This puts the fatality rate at roughly 97%.

What Is Naegleria fowleri?

Naegleria fowleri is an amoeba naturally present in warm freshwater such as ponds, lakes and rivers. It is not found in salt water or properly maintained and chlorinated pools.

The amoeba does not cause illness if swallowed. However, it can be fatal if water containing the amoeba is forced up the nose and reaches the brain. This can happen during activities such as jumping into water, diving and water-skiing.

Symptoms Of Naegleria fowleri Infection

The infection caused by N. fowleri, also called primary amebic meningoencephalitis (PAM), starts with symptoms including:

• Severe headache
• Fever
• Nausea
• Vomiting

The infection can then progress to:

• Stiff neck
• Seizures
• Coma

These rare infections usually occur when it is hot for prolonged periods, leading to higher water temperatures and lower water levels. Naegleria fowleri grows best at higher temperatures, up to 115°F.

How To Stay Safe?

While there is no way to eliminate the amoeba from the environment, some safety measures can reduce the risk:

• Prevent water from going up your nose by holding your nose shut, using nose clips or keeping your head above water during warm freshwater activities.
• Avoid putting your head underwater in hot springs and thermal waters.
• Avoid jumping or diving into warm freshwater during periods of high water temperatures and low water levels.
• Avoid digging in or stirring up sediment while taking part in water-related activities in shallow.

Norway's King Harald V died on Friday at an Oslo hospital where he was undergoing treatment for a rare blood disorder. He was 89.

“King Harald passed away peacefully at Oslo University Hospital on Friday 28 August, 0635 (local time, 0435 GMT),” the Royal Palace said on its website.

Harald, who was Europe's oldest living monarch, had been hospitalized on August 17. He was initially being treated for complications related to hemolytic anemia — a blood condition in which red blood cells are destroyed faster than the body can replace them. He later developed an infection.

King Harald V’s Health Deteriorated

Harald's condition worsened in recent days after he was admitted to hospital with fluid accumulation in the body linked to a blood disorder. He subsequently developed an infection.

Family members were called to his bedside on Thursday as his condition deteriorated at Oslo University Hospital.

Following his death, the royal flag was flown at half-mast on the palace roof.

Harald had faced several medical setbacks in recent years. He underwent heart surgeries in 2005 and 2020 and was hospitalised multiple times for infections.

What Is Hemolytic Anemia?

According to Johns Hopkins, haemolytic anaemia is a disorder in which red blood cells are destroyed faster than they can be produced. The destruction of red blood cells is known as haemolysis.

Red blood cells normally carry oxygen from the lungs to the rest of the body. When they are destroyed prematurely and faster than the bone marrow can replace them, the number of circulating red blood cells falls.

This can reduce the amount of oxygen delivered to tissues and cause symptoms such as fatigue, weakness and shortness of breath.

What Are The Symptoms Of Hemolytic Anemia?

Symptoms can vary from person to person and may include:

• Abnormally pale skin
• Yellowing of the skin and eyes (jaundice)
• Dark-coloured urine
• Fever
• Weakness
• Dizziness
• Confusion
• Reduced ability to tolerate physical activity
• Enlarged spleen or liver
• Increased heart rate (tachycardia)
• Heart murmur

These symptoms can also occur with other blood conditions or health problems. A healthcare professional should be consulted for diagnosis.

How Is Haemolytic Anaemia Diagnosed And Treated?

Diagnosis may involve tests such as:

• Complete blood count (CBC)
• Urine test
• Bone marrow aspiration or biopsy

Treatment depends on the underlying cause and may include:

• Blood transfusions
• Corticosteroid medicines
• Intravenous immune globulin to help regulate the immune system
• Rituximab

In more severe cases, treatment may include surgery to remove the spleen or immunosuppressive therapy to reduce immune-system activity.

King Harald V’s Family

Harald leaves behind his wife, Queen Sonja, his son and new King Haakon, daughter Princess Märtha Louise and six grandchildren.

Harald V was the first Norwegian-born prince in 567 years.

Following Harald's death, hundreds of people gathered outside the palace in Oslo to lay flowers, while the government declared nationwide mourning until after his funeral.

Harald's 53-year-old son will become Norway's new king, Haakon VIII, while Haakon's 22-year-old daughter Ingrid Alexandra becomes crown princess.