Credits: Canva
Until law, GLP-1 drugs were used to treat diabetes, obesity and even the recent evidences suggest that it could as well be used to treat chronic kidney problems. There is yet another research, published in JAMA Psychiatry on February 25, titled Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial that explores if GLP-1 receptor agonist semaglutide reduce alcohol consumption and cravings in adults with alcohol use disorder.
The research was conducted over a period of 9 weeks, where in the randomized clinical trial, the participants who were administered semaglutide, it led to reductions in some but not all measures of weekly consumptions. It also reduced weekly alcohol and craving related to placebo, and also led to a greater relative reduction in cigarettes per day.
The research also found that weekly injections of semaglutide, which is the active ingredient in weight loss drugs like Wegovy also helped reduce cravings in people with alcohol use disorder.
The lead author Christian Hendershot said that these findings will help in developing new approaches to treat alcoholism. "Two drugs currently approved to reduce alcohol consumption aren't widely used. The popularity of Ozempic and other GLP-1 receptor agonists increases the chances of broad adoption of these treatments for alcohol use disorder," said Hendershot in news release by the University of Southern California's Institute for Addiction Research, where he is the director.
The study is government-funded research and was funded by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health.
The study was small, and took in account for only 48 adults over two months, thus experts say that it is not yet clear how safe these drugs are for people who do not need to lose weight. Though the results do add up with the evidence form animal studies on drugs like Ozempic and Wegovy on how it helps manage cravings, not just for food, but also for tobacco and alcohol. Scientists are also studying these drugs on smokers, people with opioid addiction and cocaine users.
Co-author Dr Klara Klein of the University of North Carolina at Chapel Hill who treats people with obesity and diabetes said, "This is such promising data. And we need more of it. We frequently will hear that once people start these medications that their desire to drink is very reduced, if not completely abolished."
The GLP-1 receptor agonists work by mimicking hormones GLP-1 in the gut and brain that regulates appetite and feelings of fullness. This response is what helps one lose weight, and what helps one curb their craving for alcohol. These drugs that mimic the functioning of your brain, which is responsible to tell your body when to stop consuming, are the same hormones that tell your body about other kinds of consumptions, including alcohol. Therefore by consuming the weight loss drugs one can treat alcohol use disorder.
However, the researchers have pointed out on the limited data on the research and have suggested to continue using the three approved drugs by the National Institute on Alcohol Abuse and Alcoholism and Substance Abuse and Mental Health Services Administration, namely, Disulfiram, Naltrexone, and Acamprosate to treat alcohol use disorder until large studies confirm these findings.
Credit: iStock
Food safety has become a serious concern in the US in recent months, with a large number of products recalled over contamination, bacterial infections, and other health risks.
The latest recalls involve rice over potential foreign material contamination and mini doughnuts over undeclared milk that may trigger allergic reactions.
Packages of mini donuts sold nationwide are being recalled after a consumer reported an allergic reaction linked to the product, USA Today reported.
According to the US Food and Drug Administration (FDA), Better Bakehouse Snack Company is recalling certain lots of Donutful Chocolate Dipped Vanilla Cake Donuts because they may contain undeclared milk.
People with a milk allergy or severe sensitivity to milk could face a serious or life-threatening allergic reaction if they consume the affected product, the FDA said.
The food regulator noted that the consumer who suffered the allergic reaction has fully recovered. The manufacturer has identified the cause of the mislabeling and taken corrective measures.
Also read: From Dog Food To Fruit Bars: Over 10 Products Recalled In US Over Contamination
The recalled doughnuts are limited to a specific lot manufactured and distributed in March 2026. The product was shipped to retailers nationwide and sold through Amazon.
Consumers should check the following details to determine whether they have the recalled product:
The FDA advises consumers to dispose of the affected product and obtain a refund from the point of purchase with a receipt, or return the product for a refund.
An FDA update on August 25 provides more details about an April 2026 rice recall involving Lundberg Family Farms.
The company's Jasmine white rice was recalled because of potential contamination with foreign materials.
According to the FDA, 27,324 packages of 32-ounce rice were recalled, totaling 54,648 pounds. Lundberg-branded rice was also part of the recall initiated by the FDA in April this year.
The recalled rice was distributed in:
Consumers can identify the affected products using these details:
The expiration dates are February 1 and February 2, 2027. Consumers who were unaware of the earlier recall announcements may still have the affected product at home.
The recall follows the FDA's May 7 Class II classification.
According to the FDA, a Class II recall involves a situation in which use of or exposure to a violative product may cause temporary or medically reversible adverse health consequences, or where the likelihood of serious adverse health consequences is remote.
Credit: iStock
Belgium has been hit by a Salmonella outbreak linked to contaminated eggs, with more than 300 people falling ill, according to the country’s food safety agency. The outbreak comes after similar Salmonella outbreaks linked to contaminated eggs were reported in the US and UK.
According to the Belgian Federal Agency for the Safety of the Food Chain (FASFC), the outbreak has been linked to eggs produced by Laerco, a company based in Geel in northern Belgium.
“Salmonella is relatively common in Belgium, but we never had such a broad cluster with so many people hit,” an AFSCA spokesperson said.
No deaths have been reported in connection with the Belgian outbreak. However, officials warned that the actual number of cases could be higher, as some people may have experienced mild or no symptoms and did not seek medical testing, BOL News reported.
Also read: UK Food Agency Warns Vulnerable Groups to Avoid Runny Eggs: Who Is At Risk And Which Foods To Avoid
Salmonella was first detected at Laerco’s Geel facility at the end of April. In May, a large-scale recall was launched, with all eggs from the site withdrawn from the market.
The affected products were distributed through several major supermarket chains, including Colruyt, Delhaize, Aldi and Carrefour.
The precautionary recall was also extended to Luxembourg. FASFC notified several other European countries that may have received the eggs, including the Netherlands, France, Italy and Portugal.
As many as 2 million potentially contaminated eggs may have been sold, according to authorities.
AFSCA first discovered the contamination in May and responded by recalling the affected eggs and closing one henhouse at the farm in Flanders.
However, additional cases were reported in the following months. Officials expanded the investigation and closed the entire farm. The poultry were subsequently destroyed after a second egg recall was issued on August 10.
Secondary testing found that the bacteria had spread across multiple sheds despite initial isolation efforts, Euronews reported.
Read More: From Dog Food To Fruit Bars: Over 10 Products Recalled In US Over Contamination
The Belgian outbreak comes after the UK Health Security Agency (UKHSA) linked two deaths and 474 illnesses to three separate Salmonella Enteritidis clusters across the UK.
The US is also experiencing a Salmonella outbreak linked to eggs. The US Food and Drug Administration (FDA) upgraded the recall to its highest risk level and classified nearly 1.6 million dozen eggs as “Class I”, its most serious category for products that could cause serious adverse health consequences or death.
The multistate Salmonella outbreak has been linked to Midwest Poultry Services, L.P. person.
Salmonella is a bacterial infection that commonly causes diarrhea and gastrointestinal illness.
Common symptoms include:
Symptoms usually begin six hours to six days after swallowing the bacteria.
Most people recover from Salmonella infection without medical treatment. However, children, older adults and people with weakened immune systems may develop serious illness requiring medical care.
It can spread through contaminated food, including:
The bacteria can also spread through contact with contaminated environments or from person to person.
Health officials have advised consumers to follow recall instructions and avoid eating affected eggs. UK officials also urged vulnerable people to avoid undercooked or runny eggs, especially when dining out.
Credit: AI
A landmark clinical trial has found that four in five people with early-stage rectal cancer could avoid major surgery after receiving chemoradiotherapy and keep their rectum intact. This means that surgery would be reserved only for patients who really need it.
The findings from the STAR-TREC trial, funded by Cancer Research UK and Stand Up To Cancer, could completely change the way some people with early-stage rectal cancer are treated.
Researchers from University College London, the University of Birmingham and the University of Leeds found that combining chemotherapy and radiotherapy, followed by monitoring closely, allowed 80% of patients to avoid major surgery and keep their rectum.
Patients first receive chemoradiotherapy, which combines radiation with chemotherapy to shrink or eliminate the cancer. Doctors then closely monitor to see how the tumour responds or if the cancer grows.
If the cancer disappears or responds satisfactorily, patients can avoid major surgery. Those whose cancer does not respond adequately may still need to undergo surgery.
The trial found that four out of five patients were able to keep their rectum, avoiding the major operation. This doesn't mean that surgery is no longer necessary for rectal cancer. The findings suggest, instead, that some carefully selected patients can be treated without removing their rectum.
Researchers say this could be particularly important because around 4,100 people in England are diagnosed with early-stage rectal cancer each year.
Also read: PM2.5 Linked To 8.82 Million Global Cancer Cases, Accounts for Largest Share Among Pollutants: Study
Removing part or all of the rectum can affect how bowel function even if the cancer treatment is successful.
Some patients experience increased bowel frequency, urgency, leakage or difficulty controlling bowel movements. Others may require a stoma, in which waste leaves the body through an opening in the abdomen into a colostomy bag.
Avoiding major surgery when it is medically safe could therefore not only preserve an organ but also save the person's quality of life.
Michelle Mitchell, chief executive of Cancer Research UK, described the findings as potentially “life-changing for thousands of people.”
The non-surgical approach does not mean patients can simply finish treatment and forget about the cancer.
A major concern with preserving the rectum is that cancer could return to the same area. That's why patients following this approach require constant intensive surveillance, including scans, examinations, and other necessary tests.
If cancer returns or fails to respond adequately to the treatment, surgery for rectum removal remains an important treatment option.
The study therefore represents a shift from routinely removing the rectum upon confirmation of cancer diagnosis toward a less invasive approach based on response, where doctors can determine whether surgery is actually necessary for an individual patient.
© 2024 Bennett, Coleman & Company Limited