Heart disease is often linked to high cholesterol, obesity, or lack of exercise. However, there is mounting evidence that suggests that mental health plays a crucial role in cardiovascular well-being. Stress, anxiety, and depression can silently strain the heart, increasing the risk of serious complications.

A recent study, published in Nature Human Behaviour, showed that loneliness has a significant impact on proteins present in a person's blood. For the study, researchers used data from more than 42,000 participants to explore whether the 9.3% who reported social isolation and 6.4% who reported loneliness had different levels of proteins in their blood compared with those who did not. The researchers then studied data that tracked the health of participants over an average 14-year period.

"We found around 90% of these proteins are linked to the risk of mortality," Dr Chun Shen, Fudan University in China, who is also the lead researcher said. "In addition, about 50% of the proteins were linked to cardiovascular disease, type 2 diabetes and stroke," he added.

Dr Shrey Kumar Srivastav, senior consultant at Sharda Hospital, said that subtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked or attributed to stress and ageing. "Women, in particular, may experience atypical signs like extreme fatigue, indigestion, or upper abdominal pain instead of classic chest pain, leading to delayed diagnosis," he added.

Can Mental Health Issues Trigger Heart Diseases?

Chronic stress can trigger harmful cardiovascular effects, including elevated blood pressure, increased heart rate, and inflammation—key contributors to heart disease. Anxiety and depression further impact heart health by disrupting sleep patterns, raising stress hormone levels, and encouraging unhealthy habits like poor diet and inactivity.

Mental health issues like depression and anxiety have a profound impact on the heart. They don’t just affect emotions but can increase inflammation and put extra strain on the cardiovascular system, warns Dr Srivastav.

Certain risk factors, such as obesity and diabetes, disproportionately affect women, making them more vulnerable to heart failure with preserved ejection fraction (HFpEF). However, due to gender-specific symptom variations, heart disease in women often goes undiagnosed for longer.

Obesity is more prevalent in women than men and is a major risk factor for heart failure. Diabetes, too, has a greater impact on women’s heart health, yet diagnosis and treatment delays are common. Addressing this gap requires increasing awareness, training healthcare providers, and promoting early diagnostic tools,” explains Dr Srivastav.

How Can You Protect Your Heart?

A simple yet effective way to support heart health is by committing to a brisk 30-minute walk daily. Walking not only helps regulate blood pressure and manage weight but also improves circulation and reduces stress.

"Regular physical activity, paired with a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, significantly lowers cardiovascular risks," advises Dr Srivastav.

Heart disease can often go undetected until a major event occurs, making routine screenings essential.

- For women: Begin screenings around age 30 and continue with regular checkups.

- For men: Start screenings at age 35.

Health screenings, including blood pressure checks, cholesterol tests, and electrocardiograms (ECGs), are critical for early detection of silent heart conditions.

The Ebola outbreak in the Democratic Republic of Congo (DRC) has resulted in more than 300 deaths in a single week, marking one of the highest weekly death tolls since the outbreak began in mid-May.

According to the latest data by the DRC's Ministry of Health, 5,514 confirmed cases and 2,642 deaths had been recorded as of August 23. The outbreak, caused by the Bundibugyo virus, has already become the largest and the deadliest Ebola outbreak in history, surpassing the 2018-2020 epidemic.

Highest Weekly Death Toll

In terms of the pace of the Ebola outbreak, the latest numbers follow an alarming pattern. WHO previously reported 304 deaths and 579 cases in the week of August 3-9, the highest weekly totals recorded at that point.

An earlier WHO update had recorded 296 deaths in one week, showing how rapidly the outbreak has escalated over recent weeks.

The increase is partly linked to expanded surveillance and testing, but WHO says most of it is due to genuine expansion of the outbreak.

Rare Bundibugyo Strain Is Making Containment Challenging

Also read: DR Congo Gets 70,000 Ebola Vaccine Doses For A Different Strain: Can Ervebo Protect Against Bundibugyo?

Unlike the Zaire species of Ebola, for which licensed vaccines and treatments exist, this outbreak is being driven by Bundibugyo virus, a rare Ebola species that has not been studied adequately.

There is currently no approved vaccine specifically for Bundibugyo virus, making the response more challenging. However, DRC recently received 70,000 doses of the Ervebo vaccine, which targets Zaire strain. It is being evaluated for potential protection against Bundibugyo virus. WHO says early laboratory and animal studies suggest that the vaccine may provide some protection against Bundibugyo.

But in parts of eastern DRC, health workers face attacks, communities are displaced and people frequently move between areas. These factors allow transmission chains to continue undetected. WHO has warned that sustained transmission across communities that are interconnected is driving the aggressive expansion.

The outbreak has also been affected by misinformation and mistrust, which can discourage people from seeking treatment or cooperating with response teams.

Health Workers And Remote Communities At Major Risk

Also read: Congo's Ebola Outbreak Is Spreading Fast But WHO Says It Can Still Be Contained In 3 Months

The outbreak has spread across dozens of health zones, with Ituri remaining the epicentre. WHO reported that cases had reached at least 54 health zones across six provinces by August 12.

Health workers have also been heavily affected. At least 155 healthcare workers had contracted the virus and 45 had died as of August 9, according to WHO.

Insecurity, population displacement and poor access to healthcare are making it harder to identify cases, trace contacts and get infected people into treatment quickly.

WHO Says The Outbreak Can Still Be Contained

Despite the alarming numbers, WHO officials have said the outbreak can still be brought under control if response efforts are scaled up as soon as possible.

WHO Director-General Tedros Adhanom Ghebreyesus and Africa CDC Director-General Jean Kaseya have stressed the importance of surveillance, increasing treatment capacity and working closely with affected communities to tackle the outbreak.

NHS England has announced the rollout of free home HPV testing kits, which could make cervical screening more accessible to nearly 4 million women who are not currently up to date with their screening.

The move is being described as a “game-changer”, as around a third of eligible women are not up to date with their cervical screening. The kits aim to provide a more “discreet and convenient option” for women who may not have attended screening previously.

“Offering millions of women an alternative test they can do from the comfort of their own homes will be a game-changer – making it easier than ever for them to get tested for HPV,” said Dr Sue Mann, National Clinical Director for Women’s Health at NHS England.

Importantly, the NHS stated that the home HPV testing is "not a replacement for cervical screening". Cervical screening appointments with a clinician remains the best way to help prevent cervical cancer.

The NHS is introducing HPV self-testing as an additional option for people who have not taken up previous invitations.

The initiative is also part of the NHS pledge to eliminate cervical cancer by 2040, by making it as easy as possible for people to get lifesaving HPV vaccination and increasing cervical screening attendance.

What Does The HPV Self-Testing Kit Contain?

The self-testing kit contains a swab, similar to a long cotton bud, which is used to collect a sample from the vagina. The sample is then posted back to the NHS for free, where it is checked for high-risk HPV.

If high-risk HPV is found, individuals will be invited to book a follow-up cervical screening appointment at their GP surgery or sexual health clinic. A nurse or doctor will then take a small sample from the cervix to check for cell changes.

Who Can Get The Free Home HPV Test?

HPV self-testing is an invitation-only offer and is being rolled out in phases across England as part of the NHS Cervical Screening Programme.

The rollout starts with people aged 30 to 65 who have not attended cervical screening following previous invitations.

Women aged 24 to 64 are invited for cervical screening by the NHS every five years, or more frequently if HPV is detected.

Women who are eligible will start receiving invitations via the NHS App, text message, email or letter. Once invited, they will be able to order a free kit through the NHS App or their NHS online account.

“There are lots of reasons that may stop women from getting their cervical screening – embarrassment, lack of time, or worries about discomfort – and these kits provide a discreet and convenient option we hope will encourage more women to take up the life-saving test. So, if you’re invited to take part, please order a test – it’s a simple swab you can do at home in minutes,” she added.

Is Cervical Screening Important Even After HPV Vaccine?

Cervical screening helps prevent cervical cancer by checking for high-risk types of HPV. HPV is a common virus that can cause changes to cells in the cervix. These changes can usually be treated before cancer develops.

The NHS noted that it is still important to attend cervical screening appointments even if you have been vaccinated against HPV.

The HPV vaccine does not protect from all types of HPV, so there is still a small chance of developing cervical cancer.

People who routinely attend cervical screening with a clinician at their GP practice or sexual health clinic should continue to book their appointments as normal.

Anyone who has been invited for cervical screening can still book an appointment at any time, even if the invitation was sent months or years ago.

The US FDA has announced a nationwide recall of Vitruvias Therapeutics' Thyroid Tablets USP 30 mg over potential super-potency, which may cause hyperthyroidism (overactive thyroid).

In a recall notice issued on August 24, the company said the affected thyroid tablets, with lot number 504950, were potentially superpotent.

“Consumption of superpotent Thyroid tablets can cause hyperthyroidism (overactive thyroid) including, but not limited to, weight loss, heat intolerance, fatigue, nervousness, muscle weakness, hypertension, chest pain, rapid heart rate, or heart rhythm disturbances,” the company said.

Which Thyroid Tablets Have Been Recalled?

The recalled product is:

• Vitruvias Thyroid Tablets USP 30 mg
• Lot number: 504950
• Expiration date: September 30, 2026

The lot was distributed nationwide in the US to Vitruvias Therapeutics’ direct accounts from January 31, 2025, to September 30, 2025.

A total of 3,655 units were released, of which 1,955 were sold during the distribution period.

Who Is At Greater Risk?

The company noted that patient populations at greater risk from superpotent thyroid tablets include

• elderly people,
• pregnant women
• infants.

Excess levels of thyroid hormones in elderly people have been associated with adverse outcomes, particularly affecting cardiac health.

However, Vitruvias Therapeutics said it has not received any reports of adverse events known to be related to this recall.

The company noted that it is proactively notifying wholesalers by email and phone to discontinue distribution of the recalled product and is arranging for the destruction of all recalled products.

What To Do If You Are Taking the Recalled Product?

Patients currently taking Thyroid, USP from Lot 504950 should not discontinue use without contacting their healthcare provider for further guidance and/or a replacement prescription.

What Is the Thyroid?

The thyroid is a small gland located in the neck, but it plays an important role in the body's activities. It secretes hormones that control metabolism, or the body's ability to convert food into energy.

Thyroid hormones also regulate several other body functions, including heart rate and body temperature.

When the thyroid gland becomes underactive, a condition called hypothyroidism occurs. It causes bodily functions to slow down. Metabolism may also be reduced, leading to changes in a person's well-being.

Hypothyroidism vs Hyperthyroidism

Speaking to HealthandMe, Dr Shruti Kotangale, Consultant Gynaecologist, Obstetrician and Infertility Expert at AIMS Hospital, Dombivli, explained that conditions such as hypothyroidism and hyperthyroidism are commonly seen in women.

Hypothyroidism occurs when the thyroid gland is underactive. Symptoms can include tiredness, weight gain, dry skin, hair fall, constipation, feeling cold, a slow heartbeat and low mood or depression.

Hyperthyroidism occurs when the thyroid gland becomes overactive. Women may experience weight loss, a fast heartbeat, sweating, anxiety, tremors, irritability, frequent bowel movements, and difficulty sleeping.

Women must seek medical attention and manage these symptoms without delay.

Symptoms of Thyroid

Although weight fluctuations are the most common thyroid abnormality, they are typically accompanied by a group of symptoms, including:

• Fatigue
• Cognitive changes
• Gastrointestinal problems
• Sensitivity to cold
• Skin and hair changes

How To Diagnose?

Obtaining a proper diagnosis requires two key steps:

Physical examination: This helps determine whether there is swelling or a nodule in the neck.

Blood tests: These may determine levels of:

• TSH (thyroid-stimulating hormone)
• T4 and T3
• Thyroid antibodies, particularly when autoimmune diseases such as Hashimoto's disease or Graves' disease are suspected