Can Loneliness & Depression Harm Your Heart? Here's What Experts Say

Updated Feb 2, 2025 | 03:00 AM IST

SummarySubtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked. These signs play an important role in the early detection of heart diseases.
Depression and heart health

Depression and heart health (Credit: Canva)

Heart disease is often linked to high cholesterol, obesity, or lack of exercise. However, there is mounting evidence that suggests that mental health plays a crucial role in cardiovascular well-being. Stress, anxiety, and depression can silently strain the heart, increasing the risk of serious complications.

A recent study, published in Nature Human Behaviour, showed that loneliness has a significant impact on proteins present in a person's blood. For the study, researchers used data from more than 42,000 participants to explore whether the 9.3% who reported social isolation and 6.4% who reported loneliness had different levels of proteins in their blood compared with those who did not. The researchers then studied data that tracked the health of participants over an average 14-year period.

"We found around 90% of these proteins are linked to the risk of mortality," Dr Chun Shen, Fudan University in China, who is also the lead researcher said. "In addition, about 50% of the proteins were linked to cardiovascular disease, type 2 diabetes and stroke," he added.

Dr Shrey Kumar Srivastav, senior consultant at Sharda Hospital, said that subtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked or attributed to stress and ageing. "Women, in particular, may experience atypical signs like extreme fatigue, indigestion, or upper abdominal pain instead of classic chest pain, leading to delayed diagnosis," he added.

Can Mental Health Issues Trigger Heart Diseases?

Chronic stress can trigger harmful cardiovascular effects, including elevated blood pressure, increased heart rate, and inflammation—key contributors to heart disease. Anxiety and depression further impact heart health by disrupting sleep patterns, raising stress hormone levels, and encouraging unhealthy habits like poor diet and inactivity.

Mental health issues like depression and anxiety have a profound impact on the heart. They don’t just affect emotions but can increase inflammation and put extra strain on the cardiovascular system, warns Dr Srivastav.

Certain risk factors, such as obesity and diabetes, disproportionately affect women, making them more vulnerable to heart failure with preserved ejection fraction (HFpEF). However, due to gender-specific symptom variations, heart disease in women often goes undiagnosed for longer.

Obesity is more prevalent in women than men and is a major risk factor for heart failure. Diabetes, too, has a greater impact on women’s heart health, yet diagnosis and treatment delays are common. Addressing this gap requires increasing awareness, training healthcare providers, and promoting early diagnostic tools,” explains Dr Srivastav.

How Can You Protect Your Heart?

A simple yet effective way to support heart health is by committing to a brisk 30-minute walk daily. Walking not only helps regulate blood pressure and manage weight but also improves circulation and reduces stress.

"Regular physical activity, paired with a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, significantly lowers cardiovascular risks," advises Dr Srivastav.

Heart disease can often go undetected until a major event occurs, making routine screenings essential.

- For women: Begin screenings around age 30 and continue with regular checkups.

- For men: Start screenings at age 35.

Health screenings, including blood pressure checks, cholesterol tests, and electrocardiograms (ECGs), are critical for early detection of silent heart conditions.

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Can Meal Timing Affect Dementia Risk? Study Says Maintaining 9-Hour Eating Window Can Help

Updated Jul 27, 2026 | 07:00 PM IST

SummaryA recent study found that sticking to fixed mealtimes can help prevent cognitive decline that comes with age. It also influences the risk of dementia.
Can Meal Timing Affect Dementia Risk? Study Says Maintaining 9-Hour Eating Window Can Help

Credit: AI

A new study suggests that when you eat may be just as important as what you eat to support brain health as you age.

Researchers have found that restricting food intake to an 8 to 9-hour window each day and avoiding food for at least four hours before bedtime may help reduce age-related cognitive decline, particularly among older adults living with overweight or obesity.

The findings were presented at the American Society for Nutrition's NUTRITION 2026 annual meeting. The study supports the notion that fixed mealtimes could support healthy ageing beyond weight loss.

What Did The Study Find?

Led by researchers at Rutgers University, the study is based on 47 women aged 50 to 79 years who were overweight or obese.

All participants were enrolled in a six-month weight-loss programme and asked to consume 500 fewer calories per day. They were then divided into two groups:

Time-restricted eating group: Ate all meals within an 8 to 9-hour window, typically between 10 am and 6 pm.

Control group: Spread meals across a more conventional 12-hour eating window.

Both groups lost around 6.8 to 7 kg over six months. However, participants who followed the shorter eating window performed significantly better on tests assessing spatial planning, problem-solving, and executive function.

Researchers also noticed that they also committed fewer memory and learning errors.

Why Could Meal Timing Matter?

Also read: Scientists Say Changes In Brain In Your 40s & 50s May Influence Dementia Risk

Following fixed meal times can regulate the body's circadian rhythm, the internal biological clock that keeps sleep in check, metabolism, hormone release, and other essential brain functions.

Eating earlier in the day and avoiding late-night meals may improve metabolic health, reduce inflammation, enhance insulin sensitivity, and support healthier brain function over time. These factors are known to lower risk of cognitive decline.

Lead investigator Professor Sue Shapses, nutritional scientist at Rutgers University and Rutgers-RWJ Medical Center, said, "Losing weight alone will ward off some of the aging-related cognitive decline, and these data suggest that there may be additional benefits if you stop eating four hours before going to sleep and reduce food intake to 8 to 9 hours per day, compared with the usual eating window of 12 hours per day."

She added, "These outcomes suggest a better ability to remember information during everyday tasks and reducing mistakes related to memory, attention and problem-solving. Reductions in the eating window predicted greater improvements."

Can It Influence Dementia Risk?

Also read: Japanese PM Sanae Takaichi Sleeps 3 Hours A Night: How Much Sleep Do You Really Need?

The researchers stress that the study does not prove that a 9-hour eating window prevents dementia. Instead, it suggests that meal timing could become one of several lifestyle strategies to support cognitive health.

Dementia risk is influenced by multiple factors including age, genetics, obesity, diabetes, hypertension, physical activity, sleep, and diet. Time-restricted eating may eventually become part of a broader prevention approach if future research confirms these findings.

Dementia Risk Gets Influenced During Midlife

A recent study found that brain undergoes immune changes during 40s and 50s that could influence the risk of dementia.

Researchers found that the hippocampus, the brain region responsible for learning and memory, experiences a major shift in its immune cells during the 40s and 50s.

Once this immune environment changes, it may make the brain more vulnerable to inflammation and cognitive decline.

The findings suggest that this change could lead to chronic inflammation associated with Alzheimer's disease and other forms of dementia in the future .

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Trump Should Take A Month Off For His Health, Says Bill O'Reilly

Updated Jul 27, 2026 | 06:00 PM IST

SummaryPresident Donald Trump has repeatedly rejected suggestions that he is experiencing cognitive decline or other serious health problems. His latest annual physical examination concluded that he is "in excellent health."
Trump Should Take A Month Off For His Health, Says Bill O'Reilly

Credit: AP

US President Donald Trump should take a month-long break for his health, friend Bill O'Reilly has suggested.

The American conservative political commentator and television host made the remarks during a recent episode of his show.

“I noticed that he’s hunching over a little bit,” said O'Reilly, noting that he has known Trump for 35 years and expressing concern about the 80-year-old president's health, TV Insider reported.

“That’s normal. You get older, every malady in the world is going to visit you. I can’t even bore you with the stuff I gotta deal with. I was actually feeling sorry for myself the other day and I never do that.”

Offering advice, O'Reilly said Trump should “take the next month off, if you can.” He urged the president to “get into an environment” he enjoys, suggesting he spend time playing golf and “relax a little bit.”

Renewed Scrutiny Over Trump's Health

Questions about Trump's health have resurfaced during his second term following a series of public appearances.

Observers have pointed to swollen ankles, bruising on his hands, verbal slips, and occasional moments in which he appeared drowsy during meetings and international summits. Some physicians have also publicly raised concerns about the president's physical and cognitive health, although none have diagnosed him with dementia.

Trump has repeatedly rejected suggestions that he is experiencing cognitive decline or other serious health problems. His latest annual physical examination concluded that he is "in excellent health."

Bruising and Rash Draw Online Attention

Recent photographs have shown discoloration on both of Trump's hands. His right hand has repeatedly drawn attention in recent months for bruising that often appeared to be covered with concealer, while newer images also showed discoloration on his left hand.

“Bruising and discoloration was visible today on Trump's left hand, which is not the one that is usually mangled,” independent journalist Aaron Rupar wrote on social media platform X.

Earlier this month, Trump was also photographed with a visible neck rash and a bruised right hand that appeared to be covered with makeup during the 2026 NATO Summit in Türkiye. The back of his right hand appeared noticeably darker than the surrounding skin, suggesting cosmetic coverage, The Independent reported.

Trump has also been unsteady on his feet on some occasions, particularly while using stairs.

White House Dismisses Concerns

The White House has repeatedly rejected concerns about Trump's health, attributing the bruising to the physical demands of his schedule.

"President Trump is the sharpest, most accessible, and energetic president in American history," White House spokesperson Davis Ingle said in a statement to The Independent.

In February, White House Press Secretary Karoline Leavitt similarly said the bruising was caused by frequent handshaking.

Following Trump's most recent medical examination in May, White House physician Dr. Sean Barbabella said the bruising was consistent with "minor soft tissue irritation related to frequent handshaking" while the president was taking aspirin as a preventive measure against cardiovascular disease.

After the check-up at Walter Reed, Trump wrote on Truth Social that "everything" had "checked out PERFECTLY."

The White House has also addressed concerns over swelling around Trump's ankles, saying it is caused by blood pooling in the lower legs—a common condition among older adults.

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Quit Smoking Years Ago? New Study Says You May Still Be At The Risk Of Lung Disease

Updated Jul 27, 2026 | 03:00 PM IST

SummaryEven though quitting smoking helps reverse the damages, a recent study has found that former smokers may still be at risk of various lung diseases.
Quit Smoking Years Ago? New Study Says You May Still Be At The Risk Of Lung Disease

Credit: AI

Quitting smoking remains one of the best decisions for your health. But new research suggests that even years after your last cigarette, your lungs may continue to carry the harmful effects that increase the risk of chronic lung disease.

A new study by McGill University, published in the journal Translational Research, finds why former smokers remain at high risk to lung diseases even after quitting.

By analysing lung cells closely, scientists found that even though some damage due to smoking heals over time, other damages persist, leaving ex-smokers at a higher risk of conditions like chronic obstructive pulmonary disease (COPD) and lung cancer.

What Did The Study Find?

The study was conducted on more than 100,000 individual lung cells collected from 21 people, including nine people who had never smoked, five active smokers, and seven former smokers.

Using single-cell RNA sequencing, researchers examined molecular activity across more than 40 different lung cell types, creating one of the most comprehensive maps of how smoking and smoking cessation affect the lungs at the cellular level.

Their findings revealed that long-term lung recovery is not uniform. While some lung cells gradually regained healthier patterns after smoking cessation, others continued to show long-term molecular changes affecting tissues, immune responses, blood vessel function, and the overall lung health.

Perhaps the most surprising finding was that some cells in ex-smokers showed unique molecular markers that were not seen in active smoker and participants who never smoked, suggesting quitting smoking creates its own biological impact.

Also read: Even Light Exercise Could Help People With COPD Live Longer, Study Finds

Why Does Lung Disease Risk Persist After Quitting?

Scientists have long known that the risk of lung cancer and COPD declines after quitting smoking, but it never completely returns to the same level as seen in people who have never touched a cigarette.

Smoking damages DNA, alters gene activity, triggers chronic inflammation and injures delicate lung tissues. While the body repairs some of this damage after the smoker quits, certain cellular changes become persistent.

These lingering molecular alterations could continue influencing how lung tissue responds to injury, infections and aging.

Senior author Professor Carolyn Baglole, from McGill University's Department of Pharmacology and Therapeutics, said, "Current smokers have the highest risk of deadly diseases like lung cancer, but former smokers still face a higher risk than people who never smoked. Despite more than a century of research on smoking, we don't fully understand why."

She added, "Our findings show that while some damage appears reversible, other changes persist long after people stop smoking."

First author Nicole Heimbach, a doctoral student at McGill University, said, "These findings are an important step toward understanding what damage caused by smoking can heal and what may be permanent. By knowing what damage remains after quitting, we can better understand how smoking-related diseases develop and how to treat them."

Also read: Could Wildfire Smoke Trigger Your Migraine? Latest Study Finds A Strong Link

Thinking Of Switching To Vaping Instead Of Quitting Cigarettes?

Instead of quitting smoking, if you are thinking of switching to vaping, think again. According to a new study, vape users presented reduced fitness and impaired blood vessel function similar to traditional cigarette smokers.

The research, published in the peer-reviewed journal ERJ Open Research, compared healthy adults aged 18 to 30 and found that both regular vapers and smokers had around 15% lower exercise capacity than people who had never smoked or vaped.

This suggests that electronic cigarettes like vapes are not lesser of two evils.

The researchers, however, caution that the study does not suggest that vaping is equally harmful as smoking in every respect.

Traditional cigarettes still strongly remain linked to major disorders like cancer, chronic obstructive pulmonary disease (COPD), and many other life-threatening illnesses.

But the new study indicates that when it comes to cardiovascular fitness, breathing efficiency, lung function and blood vessel health in young adults, vaping may offer far less protection.

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