Can Loneliness & Depression Harm Your Heart? Here's What Experts Say

Updated Feb 2, 2025 | 03:00 AM IST

SummarySubtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked. These signs play an important role in the early detection of heart diseases.
Depression and heart health

Depression and heart health (Credit: Canva)

Heart disease is often linked to high cholesterol, obesity, or lack of exercise. However, there is mounting evidence that suggests that mental health plays a crucial role in cardiovascular well-being. Stress, anxiety, and depression can silently strain the heart, increasing the risk of serious complications.

A recent study, published in Nature Human Behaviour, showed that loneliness has a significant impact on proteins present in a person's blood. For the study, researchers used data from more than 42,000 participants to explore whether the 9.3% who reported social isolation and 6.4% who reported loneliness had different levels of proteins in their blood compared with those who did not. The researchers then studied data that tracked the health of participants over an average 14-year period.

"We found around 90% of these proteins are linked to the risk of mortality," Dr Chun Shen, Fudan University in China, who is also the lead researcher said. "In addition, about 50% of the proteins were linked to cardiovascular disease, type 2 diabetes and stroke," he added.

Dr Shrey Kumar Srivastav, senior consultant at Sharda Hospital, said that subtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked or attributed to stress and ageing. "Women, in particular, may experience atypical signs like extreme fatigue, indigestion, or upper abdominal pain instead of classic chest pain, leading to delayed diagnosis," he added.

Can Mental Health Issues Trigger Heart Diseases?

Chronic stress can trigger harmful cardiovascular effects, including elevated blood pressure, increased heart rate, and inflammation—key contributors to heart disease. Anxiety and depression further impact heart health by disrupting sleep patterns, raising stress hormone levels, and encouraging unhealthy habits like poor diet and inactivity.

Mental health issues like depression and anxiety have a profound impact on the heart. They don’t just affect emotions but can increase inflammation and put extra strain on the cardiovascular system, warns Dr Srivastav.

Certain risk factors, such as obesity and diabetes, disproportionately affect women, making them more vulnerable to heart failure with preserved ejection fraction (HFpEF). However, due to gender-specific symptom variations, heart disease in women often goes undiagnosed for longer.

Obesity is more prevalent in women than men and is a major risk factor for heart failure. Diabetes, too, has a greater impact on women’s heart health, yet diagnosis and treatment delays are common. Addressing this gap requires increasing awareness, training healthcare providers, and promoting early diagnostic tools,” explains Dr Srivastav.

How Can You Protect Your Heart?

A simple yet effective way to support heart health is by committing to a brisk 30-minute walk daily. Walking not only helps regulate blood pressure and manage weight but also improves circulation and reduces stress.

"Regular physical activity, paired with a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, significantly lowers cardiovascular risks," advises Dr Srivastav.

Heart disease can often go undetected until a major event occurs, making routine screenings essential.

- For women: Begin screenings around age 30 and continue with regular checkups.

- For men: Start screenings at age 35.

Health screenings, including blood pressure checks, cholesterol tests, and electrocardiograms (ECGs), are critical for early detection of silent heart conditions.

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Norway’s King Harald V Dies At 89: What Is Hemolytic Anemia?

Updated Aug 28, 2026 | 07:31 PM IST

SummaryKing ​Harald's 53-year-old son will become Norway's new king, Haakon VIII, while Haakon's 22-year-old daughter Ingrid Alexandra becomes crown princess.
Norway’s King Harald V Dies At 89: What Is Hemolytic Anemia?

Credit: AP Photos

Norway's King Harald V died on Friday at an Oslo hospital where he was undergoing treatment for a rare blood disorder. He was 89.

“King Harald passed away peacefully at Oslo University Hospital on Friday 28 August, 0635 (local time, 0435 GMT),” the Royal Palace said on its website.

Harald, who was Europe's oldest living monarch, had been hospitalized on August 17. He was initially being treated for complications related to hemolytic anemia — a blood condition in which red blood cells are destroyed faster than the body can replace them. He later developed an infection.

King Harald V’s Health Deteriorated

Harald's condition worsened in recent days after he was admitted to hospital with fluid accumulation in the body linked to a blood disorder. He subsequently developed an infection.

Family members were called to his bedside on Thursday as his condition deteriorated at Oslo University Hospital.

Following his death, the royal flag was flown at half-mast on the palace roof.

Harald had faced several medical setbacks in recent years. He underwent heart surgeries in 2005 and 2020 and was hospitalised multiple times for infections.

What Is Hemolytic Anemia?

According to Johns Hopkins, haemolytic anaemia is a disorder in which red blood cells are destroyed faster than they can be produced. The destruction of red blood cells is known as haemolysis.

Red blood cells normally carry oxygen from the lungs to the rest of the body. When they are destroyed prematurely and faster than the bone marrow can replace them, the number of circulating red blood cells falls.

This can reduce the amount of oxygen delivered to tissues and cause symptoms such as fatigue, weakness and shortness of breath.

What Are The Symptoms Of Hemolytic Anemia?

Symptoms can vary from person to person and may include:

  • Abnormally pale skin
  • Yellowing of the skin and eyes (jaundice)
  • Dark-coloured urine
  • Fever
  • Weakness
  • Dizziness
  • Confusion
  • Reduced ability to tolerate physical activity
  • Enlarged spleen or liver
  • Increased heart rate (tachycardia)
  • Heart murmur

These symptoms can also occur with other blood conditions or health problems. A healthcare professional should be consulted for diagnosis.

How Is Haemolytic Anaemia Diagnosed And Treated?

Diagnosis may involve tests such as:

  • Complete blood count (CBC)
  • Urine test
  • Bone marrow aspiration or biopsy

Treatment depends on the underlying cause and may include:

  • Blood transfusions
  • Corticosteroid medicines
  • Intravenous immune globulin to help regulate the immune system
  • Rituximab

In more severe cases, treatment may include surgery to remove the spleen or immunosuppressive therapy to reduce immune-system activity.

King Harald V’s Family

Harald leaves behind his wife, Queen Sonja, his son and new King Haakon, daughter Princess Märtha Louise and six grandchildren.

Harald V was the first Norwegian-born prince in 567 years.

Following Harald's death, hundreds of people gathered outside the palace in Oslo to lay flowers, while the government declared nationwide mourning until after his funeral.

Harald's 53-year-old son will become Norway's new king, Haakon VIII, while Haakon's 22-year-old daughter Ingrid Alexandra becomes crown princess.

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US FDA Recalls Injectables Over Fiberglass, Steel Particles: See Affected Drugs

Updated Aug 28, 2026 | 06:01 PM IST

SummaryBaxter voluntarily recalled two injections used to provide nutrition, water, and electrolytes to patients. A third injectable, anticoagulant — a substance used to slow blood clotting — was also recalled, but the affected product was distributed to only one customer.
US FDA Recalls Injectables Over Fiberglass, Steel Particles: See Affected Drugs

Credit: iStock

The US Food and Drug Administration (FDA) has announced recalls of multiple injectable drugs from Baxter International over potential contamination with fiberglass and stainless-steel particles.

Baxter voluntarily recalled:

  • two injections used to provide nutrition, water, and electrolytes to patients.
  • an injectable anticoagulant — a substance used to slow blood clotting — was also recalled, but the affected product was distributed to only one customer.

In a notice, the FDA said the medications could be contaminated with fiberglass or stainless-steel particles. Injecting contaminated products intravenously may lead to serious adverse health consequences.

“Particulate matter can cause blockage and clotting in blood vessels, which can cut off blood flow to vital organs, lead to a life-threatening blood clot in the lungs (pulmonary embolism) and cause permanent organ damage or death,” the FDA said.

“Additionally, these particles may cause local vein irritation, inflammatory reaction, aggravation of preexisting infections, and allergic

reactions,” it added. Baxter said it has not received any reports of adverse events related to the issue.

Which Medications Were Recalled?

The recalled Baxter medications include:

  • 70% Dextrose Injection, USP, 2000 mL, in a Viaflex plastic container.
  • 0.9% Sodium Chloride Injection, USP, 500 mL, in a Viaflex plastic container.
  • Anticoagulant Sodium Citrate Solution USP, 250 mL, in a Viaflex plastic container. The FDA noted that this product was distributed to only one customer.

Nutrition Injection Recalled

The 70% Dextrose Injection is a liquid solution mixed with other fluids to provide calories and nutrition through a person's veins when they cannot get necessary nutrients by mouth or through a feeding tube, USA Today reported.

The impacted products were sold between July 25 and July 28 to healthcare providers and distributors in several states, including Alabama, Georgia and Tennessee. No adverse reactions have been reported.

Water And Electrolyte Injection Recalled

The 0.9% Sodium Chloride Injection is commonly used as a source of water and electrolytes. It is administered through the veins when a person cannot get adequate amounts through eating, drinking or other medical treatments.

The injection may also be used during medical procedures, including blood transfusions and hemodialysis, a procedure that helps filter waste from the blood when the kidneys cannot do so adequately.

The impacted product was distributed between July 31 and August 3 to healthcare providers and distributors in several states, including Florida, Illinois, Indiana, Louisiana, Maryland, Missouri, North Carolina, New Jersey, Nevada, New York, Ohio, South Carolina, Texas and Virginia. No adverse reactions have been reported.

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H1N1 In Delhi: 166 Fresh Cases In 24 Hours, Tally Rises To 2,612

Updated Aug 28, 2026 | 11:57 AM IST

SummaryMost patients are presenting with flu-like symptoms, including cold, cough, body aches and upper respiratory tract infections. However, some doctors are also seeing atypical symptoms such as diarrhea also and myalgias, which are getting very, very frequent.
H1N1 In Delhi: 166 Fresh Cases In 24 Hours, Tally Rises To 2,612

Credit: iStock

India’s national capital is reporting a significant surge in influenza H1N1 cases. In the last 24 hours, Delhi reported 166 fresh H1N1 cases, up from 138 cases recorded the previous day, taking the cumulative tally to 2,612, officials said.

The total number of H1N1 cases in Delhi stood at 2,612, while cumulative Influenza-A cases were around 3,300, according to an official statement.

Delhi Reviews Hospital Preparedness

Health Minister Pankaj Kumar Singh inspected Indira Gandhi Hospital in Dwarka amid the rising number of H1N1 cases in the national capital and reviewed the hospital's and the Health Department's preparedness.

The Minister said he has been closely monitoring preparedness across hospitals.

Beyond Delhi, areas including Mumbai and Bengaluru have also reported a significant spike in H1N1 cases.

DG ICMR Dr. Rajiv Bahl said H1N1 in India is showing expected seasonal changes, with no unusual genetic shift detected.

“No cause for panic: seasonal influenza remains self-limiting; no new or unusual virus strain detected,” he added.

Doctors Flag Atypical H1N1 Symptoms

Influenza A (H1N1) is a seasonal respiratory infection that is mostly self-limiting in healthy adults. If symptoms persist beyond 5–6 days, or occur in young children, elderly persons or those with underlying medical conditions, consult a doctor or visit your nearest government health facility, the Health Ministry advised.

Dr. Atul Kakkar, Senior Consultant and Head of Department, Internal Medicine, Sir Ganga Ram Hospital, told HealthandMe that H1N1 cases are significantly higher than last year, possibly due in part to seasonal changes.

Most patients are presenting with flu-like symptoms, including cold, cough, body aches and upper respiratory tract infections.

However, doctors are also seeing atypical symptoms.

“We are seeing patients having diarrhea also and myalgias, which are getting very, very frequent.”

Patients at extreme ages are more prone to complications and may require oxygen, high-flow oxygen, NIV or BiPAP, he said. Those at higher risk include people who are unvaccinated against flu, patients undergoing chemotherapy, and those with COPD, bronchial asthma, cancer or those on immunosuppressive treatment.

H1N1 Can Affect The Heart

As per experts, H1N1 infection may also be associated with cardiovascular complications, including:

  • Heart inflammation
  • Abnormal heartbeats
  • Worsening heart failure
Dr. Saurabh Gupta, Associate Director, Internal Medicine, Yashoda Medicity, said H1N1 may cause fluctuations in heart rhythm or inflammation involving the heart.

“Those with pre-existing heart conditions should be more vigilant whilst they’re recuperating. As the infection puts more work on the body, you can find that previous heart problems are more noticeable,” he added.

H1N1 Can Affect The Eyes

While H1N1 primarily causes fever and respiratory symptoms, some people also have some eye discomfort and sudden vision changes.

Dr. Maitri Jindal Chowdhary, Consultant, Ophthalmology: Yashoda Medicity told HealthandMe that eye symptoms during H1N1 may manifest as a bit of redness, watery eyes, some irritation or dryness, which should resolve as the H1N1 is overcome. But a change in vision definitely warrant an eye professional’s attention.

The expert said that vision changes such as blurry or double vision, acute vision loss, seeing flashes of light or floaters or a drop in your vision should be brought to the attention of an eye doctor. Don’t automatically attribute such vision changes to your “flu”.

"Some eye concerns are of course not as serious. There might be some watering of eyes, slight discomfort that resolve as you feel better. However if symptoms such as sudden blurry vision persists, if eye irritation persists or worsens – you need to get yourself checked out.

Likewise if you feel pain in the eye, there’s an alarming redness, a lot of light sensitivity, swelling or an discharge - go get those eyes checked out," Dr. Maitri told HealthandMe.

Be very careful if you wear contact lenses. Do not wear them if your eyes become red, painful or vision blurring as this could worsen the issue. Remove your contacts immediately and seek attention.

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