Can Loneliness & Depression Harm Your Heart? Here's What Experts Say

Updated Feb 2, 2025 | 03:00 AM IST

SummarySubtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked. These signs play an important role in the early detection of heart diseases.
Depression and heart health

Depression and heart health (Credit: Canva)

Heart disease is often linked to high cholesterol, obesity, or lack of exercise. However, there is mounting evidence that suggests that mental health plays a crucial role in cardiovascular well-being. Stress, anxiety, and depression can silently strain the heart, increasing the risk of serious complications.

A recent study, published in Nature Human Behaviour, showed that loneliness has a significant impact on proteins present in a person's blood. For the study, researchers used data from more than 42,000 participants to explore whether the 9.3% who reported social isolation and 6.4% who reported loneliness had different levels of proteins in their blood compared with those who did not. The researchers then studied data that tracked the health of participants over an average 14-year period.

"We found around 90% of these proteins are linked to the risk of mortality," Dr Chun Shen, Fudan University in China, who is also the lead researcher said. "In addition, about 50% of the proteins were linked to cardiovascular disease, type 2 diabetes and stroke," he added.

Dr Shrey Kumar Srivastav, senior consultant at Sharda Hospital, said that subtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked or attributed to stress and ageing. "Women, in particular, may experience atypical signs like extreme fatigue, indigestion, or upper abdominal pain instead of classic chest pain, leading to delayed diagnosis," he added.

Can Mental Health Issues Trigger Heart Diseases?

Chronic stress can trigger harmful cardiovascular effects, including elevated blood pressure, increased heart rate, and inflammation—key contributors to heart disease. Anxiety and depression further impact heart health by disrupting sleep patterns, raising stress hormone levels, and encouraging unhealthy habits like poor diet and inactivity.

Mental health issues like depression and anxiety have a profound impact on the heart. They don’t just affect emotions but can increase inflammation and put extra strain on the cardiovascular system, warns Dr Srivastav.

Certain risk factors, such as obesity and diabetes, disproportionately affect women, making them more vulnerable to heart failure with preserved ejection fraction (HFpEF). However, due to gender-specific symptom variations, heart disease in women often goes undiagnosed for longer.

Obesity is more prevalent in women than men and is a major risk factor for heart failure. Diabetes, too, has a greater impact on women’s heart health, yet diagnosis and treatment delays are common. Addressing this gap requires increasing awareness, training healthcare providers, and promoting early diagnostic tools,” explains Dr Srivastav.

How Can You Protect Your Heart?

A simple yet effective way to support heart health is by committing to a brisk 30-minute walk daily. Walking not only helps regulate blood pressure and manage weight but also improves circulation and reduces stress.

"Regular physical activity, paired with a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, significantly lowers cardiovascular risks," advises Dr Srivastav.

Heart disease can often go undetected until a major event occurs, making routine screenings essential.

- For women: Begin screenings around age 30 and continue with regular checkups.

- For men: Start screenings at age 35.

Health screenings, including blood pressure checks, cholesterol tests, and electrocardiograms (ECGs), are critical for early detection of silent heart conditions.

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Childhood Obesity Is A 'Do or Die' Crisis, Experts Warn At Times Network India Health Summit 2026

Updated Jun 20, 2026 | 07:58 PM IST

SummaryThe rising obesity levels in India are reaching a 'do or die' crisis level, and it is important to rein in the unhealthy eating habits for a healthy nation, warned experts at the ongoing Times Network India Health Summit 2026 today at Hyderabad.
Childhood Obesity Is A 'Do or Die' Crisis, Experts Warn At Times Network India Health Summit 2026

Credit: Times Network Health Summit 2026

The experts stressed the urgent need to tackle India's growing obesity crisis—particularly among children.

Speaking during a panel discussion on the future of women's and child healthcare, Dr. Sivaranjani Santosh, often referred to as the "ORS Lady of India," praised India's public health achievements, including the successful Pulse Polio Program, malaria control efforts, and improvements in child nutrition.

However, she cautioned that new challenges now threaten the country's health gains.

"There were many things we are lagging a bit also," Dr. Santosh said, stressing the need for fair food labelling, responsible marketing, and stricter regulation of irrational drug combinations.

She issued a stark warning about unhealthy eating habits, saying, "This junk food pandemic, this is where India needs to really, really focus on. Childhood obesity is a pandemic now. And it's like do or die right now for us."

Her comments highlighted growing concerns that poor nutrition and processed foods are driving obesity among children, increasing their risk of chronic illnesses later in life.

Also Read: Times Now Health Summit 2026: AI Cannot Replace Doctors, It Can Only Complement, Says Dr Santosh Sivaranjani

Echoing the concerns, Dr. T. Rajeshwari Reddy, Senior Consultant Obstetrician, Gynecologist, and Laparoscopic and Robotic Surgeon at Continental Hospital, explained that unhealthy lifestyles beginning in childhood are now contributing to a rise in hormonal disorders, infertility, and high-risk pregnancies.

"We are seeing a lot of people with hormonal imbalances and a lot of issues from teens, and that is what gets translated into infertility and high-risk pregnancy," she said.

Dr. Rajeshwari stressed that prevention must begin early. "The beginning has to be from birth only," she said, urging families to prioritize home-cooked meals, healthy routines, adequate sleep, and reduced screen time. She added that preventive healthcare should become the foundation of India's health strategy over the next decade.

Experts agreed that the future of Indian healthcare will depend on preventive medicine, technology, artificial intelligence, and stronger public-private partnerships to improve access to healthcare, particularly in rural areas.

They urged that India's fight against childhood obesity and lifestyle-related diseases must begin at home, with healthier food choices, greater awareness, and prevention from an early age.

Meanwhile, the AI in healthcare panel featured Prof. Renu John, IIT Hyderabad; Nishan Ali, Founder & CEO, Neurologic AI; Dr. Rahul Sawakhande, CEO, Aakaar Medical Technologies; and Dr. Rajah V. Koppala, Vascular & Interventional Radiologist and Founder, AVIS Vascular Center. The experts discussed how AI is driving predictive, data-led healthcare by improving diagnostics, telemedicine, and early disease detection while complementing doctors. They also stressed the need for better regulations, India-specific datasets, stronger data privacy, and greater collaboration between clinicians and engineers to expand quality healthcare across India.

The Times Now India Health Summit 2026 – South Edition commenced in Hyderabad, bringing together leading voices from government, medicine, research, and the healthcare industry to discuss the future of India's healthcare system. The summit featured renowned doctors, policymakers, hospital leaders, researchers, and healthcare innovators, with discussions spanning preventive healthcare, artificial intelligence, women's health, public health policy, and medical innovation.

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Ebola Outbreak Crosses 900 Cases, 200 Deaths In DRC, Uganda; WHO Says Outbreak Spreading Rapidly

Updated Jun 19, 2026 | 11:44 PM IST

Summary​Africa CDC epidemiologist Dr. Wessam Mankoula said the outbreak is approximately three times larger than any previous Ebola outbreak at a similar stage. Cases in Congo and Uganda have reached 915, while deaths has climb to 210.
Ebola Outbreak Crosses 900 Cases, 200 Deaths In DRC And Uganda

Credit: iStock

The Ebola outbreak caused by the Bundibugyo virus has reached 915 confirmed cases and 210 deaths in the Democratic Republic of the Congo (DRC) and Uganda, according to the Africa Centers for Disease Control and Prevention (Africa CDC).

The situation remains serious, with ongoing transmission reported in eastern DRC. Ituri Province continues to be the epicentre of the outbreak, accounting for the majority of confirmed cases in the country. The most affected health zones include Bunia, Mongbwalu, and Rwampara.

North Kivu has reported fewer cases than Ituri but has recorded a higher case-fatality rate, particularly in Katwa and Beni. Health officials say this underscores the need for early detection, safe referrals, quality clinical care, and strengthened infection prevention and control measures.

In Uganda, 19 confirmed cases and two deaths have been reported to date. No new cases have been recorded since June 5, 2026.

Community Mistrust Hindering Response Efforts

Africa CDC has identified several challenges hampering response efforts, including gaps in

  • contact tracing,
  • shortages of personal protective equipment (PPE)
  • essential medical supplies,
  • limited ambulance capacity,
  • community concerns surrounding isolation,
  • post-mortem testing,
  • household decontamination.

"Communities are central to stopping this outbreak. The response will only succeed if people trust the information they receive, know where to seek care, and feel that response teams are working with them," Africa CDC said in a statement.

Also read: US FDA Panel Recommends First-Ever mRNA Flu Shot For Older Adults: All About The Moderna Vaccine

WHO Warns Outbreak Is Spreading Rapidly

Meanwhile, the World Health Organization (WHO) had warned that the outbreak is spreading rapidly, even as response measures are being intensified.

"The outbreak remains serious and is evolving very fast. However, I have seen a response that is growing stronger every day," said Marie-Roseline Belizaire, WHO Regional Emergencies Director for Africa, speaking to reporters in Bunia, the epicentre of the outbreak.

The WHO estimates that at least 95 per cent of contacts must be traced to effectively contain the outbreak. As per Belizaire, contact tracing has improved to 75 per cent.

Read More: Natural Origin or Lab Leak? Gabbard Reignites COVID Origins Debate, Claims Fauci Funded Wuhan Lab Research

Ebola Outbreak 3 Times Larger

Africa CDC epidemiologist Dr. Wessam Mankoula said the outbreak is approximately three times larger than any previous Ebola outbreak at a similar stage, four weeks after a public health emergency declaration, AP News reported.

Although the outbreak was officially declared on May 15, health officials believe the virus had been circulating undetected for some time beforehand, contributing to its wider spread.

Another major concern is that the outbreak is being driven by the Bundibugyo strain of Ebola virus, for which there are currently no approved antiviral treatments.

Community mistrust of healthcare workers and public health officials, along with reliance on traditional beliefs and healers, is also complicating containment efforts.

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US FDA Panel Recommends First-Ever mRNA Flu Shot For Older Adults: All About The Moderna Vaccine

Updated Jun 19, 2026 | 05:22 PM IST

SummaryThe panel backed the vaccine, known as mFLUSIVA, for adults aged 50 years and older, concluding that its benefits outweigh its risks.
US FDA Panel Recommends First-Ever mRNA Flu Shot For Older Adults: All About The Moderna Vaccine

Credit: iStock

The US Food and Drug Administration's independent advisory panel has recommended approval of Moderna's mRNA-based influenza vaccine for older adults.

The panel backed the vaccine, known as mFLUSIVA, for adults aged 50 years and older, concluding that its benefits outweigh its risks.

If ultimately approved by the FDA, mFLUSIVA would become the world's first messenger RNA (mRNA) vaccine for seasonal influenza. The development could provide a new tool against a disease that causes an estimated 15 million to 60 million illnesses, 180,000 to 700,000 hospitalizations, and 17,000 to 75,000 deaths annually in the United States, according to data from the US Centers for Disease Control and Prevention (CDC).

What Did The FDA Advisory Panel Decide?

The recommendation came from the Vaccines and Related Biological Products Advisory Committee (VRBPAC), which reviews vaccine applications and advises the FDA.

The meeting marked the committee's first review of a new vaccine application since 2023 and could lead to the first vaccine approval under the second Trump administration.

In a unanimous vote, all nine panel members supported the use of Moderna's mFLUSIVA vaccine for adults aged 50 to 64 years, as well as for those aged 65 years and older—the age group that had previously raised regulatory concerns.

Also read: No Women Aged 20-24 Died of Cervical Cancer in England Over Five Years, Thanks to HPV Vaccine

However, before the vaccine can be made available for the upcoming flu season, it must receive formal FDA approval and be recommended by the CDC's Advisory Committee on Immunization Practices (ACIP). The CDC advisory panel has not recently convened due to ongoing legal and administrative challenges. An FDA decision on the vaccine is expected by August 5.

How Effective Is Moderna's mRNA Flu Vaccine?

According to Moderna, the vaccine outperformed standard-dose flu vaccines in adults aged 50 to 64 years.

In a large clinical trial involving approximately 40,000 adults aged 50 years and older, Moderna's mRNA vaccine reduced influenza cases by about 27% compared with another routinely used flu vaccine.

The company also conducted a smaller study among adults aged 65 years and older. The results showed that mFLUSIVA generated a strong immune response compared with a high-dose influenza vaccine already recommended for seniors.

FDA adviser Dr. Anna Durbin of Johns Hopkins University described the immune-response data as "very compelling," adding that "the vaccine looks very promising," AP News reported.

How Does The Vaccine Work?

Read More: Sickle Cell Disease: Why India Must Add Curative Treatment to Meet Its 2047 Elimination Goal

Like Moderna's COVID-19 vaccines, mFLUSIVA uses messenger RNA technology. Rather than introducing a weakened or inactivated virus, mRNA vaccines deliver genetic instructions that help the body's cells produce proteins that trigger an immune response. This approach allows vaccines to be updated more quickly and may improve protection against evolving viruses.

Is The Vaccine Safe?

Moderna's data showed no major safety concerns.

The most commonly reported side effects included:

  • Injection-site pain
  • Fever
  • Headache
  • Fatigue
  • Muscle aches

These reactions were generally temporary and are commonly seen with many vaccines. However, they occurred somewhat more frequently than with currently available flu vaccines. FDA reviewers noted that this is typical of mRNA-based vaccines.

What's Next?

If approved, Moderna plans to conduct a large post-approval study involving approximately 400,000 adults aged 65 years and older.

Half of the participants will receive the mRNA vaccine, while the other half will receive one of the currently recommended flu vaccines for seniors. The study is expected to continue across two influenza seasons.

A Moderna executive said the company hopes to make the vaccine available to patients in time for the upcoming flu season, Reuters reported.

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