Depression and heart health (Credit: Canva)
Heart disease is often linked to high cholesterol, obesity, or lack of exercise. However, there is mounting evidence that suggests that mental health plays a crucial role in cardiovascular well-being. Stress, anxiety, and depression can silently strain the heart, increasing the risk of serious complications.
A recent study, published in Nature Human Behaviour, showed that loneliness has a significant impact on proteins present in a person's blood. For the study, researchers used data from more than 42,000 participants to explore whether the 9.3% who reported social isolation and 6.4% who reported loneliness had different levels of proteins in their blood compared with those who did not. The researchers then studied data that tracked the health of participants over an average 14-year period.
"We found around 90% of these proteins are linked to the risk of mortality," Dr Chun Shen, Fudan University in China, who is also the lead researcher said. "In addition, about 50% of the proteins were linked to cardiovascular disease, type 2 diabetes and stroke," he added.
Dr Shrey Kumar Srivastav, senior consultant at Sharda Hospital, said that subtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked or attributed to stress and ageing. "Women, in particular, may experience atypical signs like extreme fatigue, indigestion, or upper abdominal pain instead of classic chest pain, leading to delayed diagnosis," he added.
Can Mental Health Issues Trigger Heart Diseases?
Chronic stress can trigger harmful cardiovascular effects, including elevated blood pressure, increased heart rate, and inflammation—key contributors to heart disease. Anxiety and depression further impact heart health by disrupting sleep patterns, raising stress hormone levels, and encouraging unhealthy habits like poor diet and inactivity.
Mental health issues like depression and anxiety have a profound impact on the heart. They don’t just affect emotions but can increase inflammation and put extra strain on the cardiovascular system, warns Dr Srivastav.
Certain risk factors, such as obesity and diabetes, disproportionately affect women, making them more vulnerable to heart failure with preserved ejection fraction (HFpEF). However, due to gender-specific symptom variations, heart disease in women often goes undiagnosed for longer.
Obesity is more prevalent in women than men and is a major risk factor for heart failure. Diabetes, too, has a greater impact on women’s heart health, yet diagnosis and treatment delays are common. Addressing this gap requires increasing awareness, training healthcare providers, and promoting early diagnostic tools,” explains Dr Srivastav.
How Can You Protect Your Heart?
A simple yet effective way to support heart health is by committing to a brisk 30-minute walk daily. Walking not only helps regulate blood pressure and manage weight but also improves circulation and reduces stress.
"Regular physical activity, paired with a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, significantly lowers cardiovascular risks," advises Dr Srivastav.
Heart disease can often go undetected until a major event occurs, making routine screenings essential.
- For women: Begin screenings around age 30 and continue with regular checkups.
- For men: Start screenings at age 35.
Health screenings, including blood pressure checks, cholesterol tests, and electrocardiograms (ECGs), are critical for early detection of silent heart conditions.
Credits: Canva
Los Angeles County has recorded its first flu-related death of the season, the LA County Department of Public Health announced Wednesday.
The individual was an “older adult” with pre-existing health conditions. Officials noted that the person had likely not received a flu vaccine for this season, which generally spans from October through May.
Although flu cases are still low in November, health authorities expect the number of infections to rise as holiday travel and indoor gatherings increase.
"The LA County Department of Public Health reported Wednesday the first flu-related death of the season in Los Angeles County. “We extend our condolences to the family and loved ones of the deceased. This sad loss underscores the serious risks posed by influenza,” said Dr. Muntu Davis, Los Angeles County health officer, in a news release.
Flu activity remains low for now, but it is anticipated to climb around Thanksgiving and the broader holiday period, when travel and indoor events are more common.
Experts advise getting vaccinated at least two weeks before holiday travel or gatherings, since it takes time for immunity to develop.
They also recommend wearing a properly fitted mask in crowded indoor settings, particularly for households with older adults, children under five, or pregnant women.
The Centers for Disease Control and Prevention (CDC) recommends that everyone aged six months and older receive an annual influenza vaccine, with rare exceptions for specific medical conditions. Annual vaccination is especially important for high-risk groups, including:
Timing: The ideal time to get a flu shot is before flu activity peaks, usually in early fall. It takes about two weeks after vaccination for the body to build full immunity, so getting vaccinated before holiday travel and gatherings is crucial.
Several flu vaccines are available, including standard-dose, high-dose for older adults, and nasal spray options for certain age groups. Your healthcare provider can recommend the most appropriate option based on age, health status, and any contraindications.
Flu vaccines are generally safe. Mild side effects like soreness at the injection site, low-grade fever, or fatigue may occur, but serious reactions are extremely rare. Individuals with severe allergies to vaccine components should consult their healthcare provider before vaccination.
Even after vaccination, preventive measures such as frequent handwashing, wearing masks in crowded indoor spaces, and avoiding contact with sick individuals can help reduce flu transmission.
Credits: Canva/CDC
The U.S. Centers for Disease Control and Prevention is promoting a long-debunked theory, suggesting a potential link between vaccines and autism, and claiming that studies supporting this connection “have been ignored by health authorities.”
The disputed theory appeared on a revised section of the CDC’s website under “Autism and Vaccines” on Wednesday. The website now states: “The statement ‘Vaccines do not cause autism’ is not an evidence-based claim. Scientific studies have not ruled out the possibility that infant vaccines contribute to the development of autism.
However, this statement has historically been shared by the CDC and other federal health agencies within HHS to prevent vaccine hesitancy.” The agency added that the U.S. Department of Health and Human Services has “launched a thorough review of the causes of autism, including investigations on plausible biological mechanisms and potential causal links.”
It also noted, “This webpage will be updated with gold-standard science.” Prior to Wednesday, the page stated there is “no link” between vaccines and autism, and no vaccine ingredients were connected to the condition, according to archived versions cited by The Washington Post.
Another part of the site, “About Vaccines for Your Children,” last updated in August 2024, still asserts, “Scientific studies and reviews continue to show no relationship between vaccines and autism.” Dr. Demetre Daskalakis, a former CDC official who resigned earlier this year as head of the National Center for Immunization and Respiratory Diseases, criticized the changes, saying on X, “The weaponization of the voice of CDC is getting worse. DO NOT TRUST THIS AGENCY. This is a national embarrassment.” Despite the new language, the header “Vaccines do not cause autism” remains due to an agreement with Sen. Bill Cassidy (R-La.), chair of the Senate Health Committee, who cast the deciding vote to advance Health Secretary Robert F. Kennedy Jr.’s nomination to the full Senate floor.
The revisions surprised CDC staff, including those overseeing vaccine safety and autism information, leaving them blindsided, according to The Post. “We just saw it, and everyone is freaking out,” one scientist said, as per NBC News.
While the changes could undermine public confidence in vaccines, Kennedy and Trump have historically supported this theory. Both have also warned against Tylenol use during pregnancy, claiming a link to autism, despite large-scale studies disproving any connection.
Autism spectrum disorder, or autism, is a condition that affects the brain, making it challenging for some people to communicate and interact with others. Experts still don’t fully understand what causes it.
The idea that vaccines might play a role largely began with a 1998 study suggesting that the MMR (measles-mumps-rubella) vaccine—or infection with the natural measles virus—could lead to autism. Since then, numerous scientific studies have shown there is no connection between vaccines or any of their ingredients and autism.
The 1998 study itself was later discredited: the research was found to be false, the doctor responsible lost his medical license, and the journal that published the paper retracted it, acknowledging it should never have been published.
Despite strong evidence showing vaccines are safe and effective, some parents still choose to delay or skip vaccinations for their children. This can be very dangerous, as diseases like measles, which vaccines prevent, are still circulating. An unvaccinated child who contracts one of these illnesses can become seriously ill or even die and may also put others at risk.
While mild reactions like a fever or rash can occur after vaccination, the chance of a serious side effect from the MMR or other recommended vaccines is very small compared to the risks of the diseases they protect against.
Credits: Gemini
A major claim from China has sparked global curiosity and debate after a Shenzhen-based biotechnology company announced that it has developed a longevity pill capable of significantly slowing ageing.
A biotechnology company in Shenzhen, China, has caught worldwide attention by claiming to have created a pill that could dramatically slow the ageing process. According to the firm, the pill may one day help humans live up to 150 years by targeting ageing at the cellular level.
As per The Independent, Lonvi Biosciences says its formula focuses on ‘zombie cells’—aged cells that refuse to die, causing inflammation and age-related illnesses. Let’s take a closer look at the pill and explore whether this ambitious claim could be possible.
The Shenzhen-based company, part of China’s rapidly growing longevity industry, claims it has produced a pill that could theoretically stretch human life to 150 years. The formula targets so-called “zombie cells”—older cells that resist dying, leading to inflammation and disease associated with ageing. “This is not just another pill. This is the Holy Grail,” said CEO Ip Zhu, calling the capsule a breakthrough that could make extreme longevity achievable. The main ingredient comes from grape seeds and has shown in lab studies to extend lifespan in animals by delaying age-related diseases. Lonvi’s researchers suggest that taking the pill in adulthood could push life expectancy past 120, while starting from birth could surpass 150.
The pill contains procyanidin C1 (PCC1), a compound extracted from grape seeds. In experiments with mice, Lonvi claims the treatment increased overall lifespan by 9.4%, with a remarkable 64% improvement when dosing started from the very beginning. Lyu Qinghua, Lonvi’s chief technology officer, told The New York Times that reaching 150 is “definitely realistic” and could be possible “within a few years.”
China has made anti-ageing research a national priority, with President Xi Jinping reportedly discussing it with Russian President Vladimir Putin. Anti-ageing research, combined with AI and biotech, has quickly moved from niche interest to mainstream focus in the country.
A study in Nature Metabolism showed that procyanidin C1 from grape seed extract successfully extended both the lifespan and health span of mice, paving the way for future clinical trials.
Cellular senescence plays a key role in ageing, occurring when cells can no longer perform their functions. In recent years, researchers have identified drugs called senolytics, which can eliminate these senescent cells in the lab and in animal studies. This approach is an important step toward reducing age-related chronic diseases and could play a critical role in extending lifespan.
While the company’s claims have not yet been tested in human trials, scientists believe the approach holds promise for extending life. Lonvi’s researchers say the PCC1 pill can boost cellular health, delay deterioration, and maintain energy production over time. They suggest that when combined with a healthy lifestyle, the pill could help people live beyond 100, and possibly even past 120, while also reducing diseases linked to ageing.
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