Can Loneliness & Depression Harm Your Heart? Here's What Experts Say

Updated Feb 2, 2025 | 03:00 AM IST

SummarySubtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked. These signs play an important role in the early detection of heart diseases.
Depression and heart health

Depression and heart health (Credit: Canva)

Heart disease is often linked to high cholesterol, obesity, or lack of exercise. However, there is mounting evidence that suggests that mental health plays a crucial role in cardiovascular well-being. Stress, anxiety, and depression can silently strain the heart, increasing the risk of serious complications.

A recent study, published in Nature Human Behaviour, showed that loneliness has a significant impact on proteins present in a person's blood. For the study, researchers used data from more than 42,000 participants to explore whether the 9.3% who reported social isolation and 6.4% who reported loneliness had different levels of proteins in their blood compared with those who did not. The researchers then studied data that tracked the health of participants over an average 14-year period.

"We found around 90% of these proteins are linked to the risk of mortality," Dr Chun Shen, Fudan University in China, who is also the lead researcher said. "In addition, about 50% of the proteins were linked to cardiovascular disease, type 2 diabetes and stroke," he added.

Dr Shrey Kumar Srivastav, senior consultant at Sharda Hospital, said that subtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked or attributed to stress and ageing. "Women, in particular, may experience atypical signs like extreme fatigue, indigestion, or upper abdominal pain instead of classic chest pain, leading to delayed diagnosis," he added.

Can Mental Health Issues Trigger Heart Diseases?

Chronic stress can trigger harmful cardiovascular effects, including elevated blood pressure, increased heart rate, and inflammation—key contributors to heart disease. Anxiety and depression further impact heart health by disrupting sleep patterns, raising stress hormone levels, and encouraging unhealthy habits like poor diet and inactivity.

Mental health issues like depression and anxiety have a profound impact on the heart. They don’t just affect emotions but can increase inflammation and put extra strain on the cardiovascular system, warns Dr Srivastav.

Certain risk factors, such as obesity and diabetes, disproportionately affect women, making them more vulnerable to heart failure with preserved ejection fraction (HFpEF). However, due to gender-specific symptom variations, heart disease in women often goes undiagnosed for longer.

Obesity is more prevalent in women than men and is a major risk factor for heart failure. Diabetes, too, has a greater impact on women’s heart health, yet diagnosis and treatment delays are common. Addressing this gap requires increasing awareness, training healthcare providers, and promoting early diagnostic tools,” explains Dr Srivastav.

How Can You Protect Your Heart?

A simple yet effective way to support heart health is by committing to a brisk 30-minute walk daily. Walking not only helps regulate blood pressure and manage weight but also improves circulation and reduces stress.

"Regular physical activity, paired with a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, significantly lowers cardiovascular risks," advises Dr Srivastav.

Heart disease can often go undetected until a major event occurs, making routine screenings essential.

- For women: Begin screenings around age 30 and continue with regular checkups.

- For men: Start screenings at age 35.

Health screenings, including blood pressure checks, cholesterol tests, and electrocardiograms (ECGs), are critical for early detection of silent heart conditions.

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Delhi Kidnappings Were False Fear Mongering, Officials Confirm

Updated Feb 6, 2026 | 04:30 PM IST

SummaryDays after it emerged that over 800 people had gone missing in Delhi, police has revealed this is false and such claims are being "pushed through paid promotion" Authorities across the capital claim that dispensing false information about information such as kidnappings through paid promotion can cause fear among the general public, which can massively ruin mental health
Delhi Kidnappings Were False Fear Mongering, Officials Confirm

Days after it emerged that over 800 people had gone missing in Delhi during the first 27 days of 2026 and officials requested people to remain calm, Delhi Police has revealed this is false and such claims are being "pushed through paid promotion".

In a statement released on X today morning: "After following a few leads, we discovered that the hype around the surge in missing girls in Delhi is being pushed through paid promotion. Creating panic for monetary gains won't be tolerated, and we'll take strict action against such individuals."

Authorities across the capital claim that dispensing false information about life-altering information such as kidnappings and death through paid promotion can cause as well as amplify fear among the general public, which can massively ruin mental health and cause long-term damage to overall wellbeing.

Dr Kunal Bahrani, Chairman and Group Director, Neurology at Yatharth Hospitals, explained to Healthandme: "Incidents like this highlight how quickly fear can spread in today’s hyperconnected world and how deeply false news can impact mental wellbeing. When people are exposed to alarming information, especially involving safety and crime, the brain’s threat system switches on almost instantly. Stress hormones such as cortisol surge, increasing anxiety, restlessness, sleep disturbances and even physical symptoms like headaches or heart palpitations.

"Repeated exposure to frightening but unverified news can also condition the brain to remain in a constant state of alert, making individuals more irritable, emotionally overwhelmed and prone to panic. For children, elderly people and those already struggling with anxiety or depression, the psychological impact can be far more intense and long-lasting."

However, while many wonder how this form of promotion came into being, Reddit users are already pointing towards Rani Mukerji's Mardaani-3, a movie based on the kidnapping of minor girls as the source for this chaos.

How Does Fear Mongering Ruin Mental Wellbeing?

Fear-mongering severely impacts mental health by triggering chronic stress, anxiety, and depression, often overloading the brain’s threat response system (amygdala) and leading to long-term damage.

Over time, constant exposure to exaggerated, alarming narratives fuels irrational fears and cognitive distortions such as catastrophizing. This constant state of fear can also lead to avoidance behaviors, hopelessness, and physical symptoms like headaches, poor sleep and a weakened immune system.

Dr Neetu Tiwari, MD Psychiatry Senior Resident, NIIMS Medical College & Hospital also told Healthandme: "When things like this happen around us, it creates a sense of panic and fear amongst parents and children. Our brain usually reacts as if the danger is real. The body then becomes alert, our heart beats faster than it should, and our mind stays at tense. Even if the news is proven to be false, this fear that has set in often takes time to settle down.

"Now this in turn causes a lot of trouble. It makes people feel unsafe, so people avoid going out, they worry more about loved ones, or may also keep checking their phones repeatedly for updates. This behavior can lead to anxiety, panic, disturbed sleep, and constant overthinking. Even when the news is fake, fear travels very quickly. And once fear enters our mind, calming down takes time.

"This is why sharing unverified information can unknowingly harm others especially children as it can lead them in feeling scared even to go to school, or sleep alone, or even step outside. In fact in some children this may even cause nightmares or these children become unusually clingy to parents or guardians which further leads to problem in social development and confidence.

Dr. Rajiv Mehta, senior consultant psychologist, Sir Gangaram Hospital added: "The society at large is very gullible and anxiety prone, as we have seen the rise in mental illnesses. The people who are already anxious will get more anxious, the people who are not anxious will get anxious and that will increase the mental instability in the persons.

"And what they and parents are going to do is take a lot of precautions towards their young kids by not allowing them to go outside, to play with the children and go out of society buildings. They will be very fearful and when children will be home bound, then they will spend more time on screens or will have altercations with their parents.

"People should not resort to such kind of things only for the sake of their own materialistic monetary benefit. That is highly condemnable if it has occurred because of these kind of reasons that movie is going to release and they are sensationalizing these things."

Are The Delhi Kidnappings False?

Data obtained from Press Trust of India suggests that a total of 807 people went missing between January 1 and 15, with an average of 54 people going missing every day. Of these, 509 were women and girls, and 298 were men. Among the total reported missing, 191 were minors and 616 were adults.

In an official statement, the police said that, while the data was recorded, January 2026 saw a "decline in the number of missing persons reports when compared with the corresponding period of previous years."

Officials had previously further clarified that no organized gang or criminal network has been found involved in cases of missing or abducted children in Delhi so far.

"Recent public discourse has raised concerns about the welfare of children in Delhi. We appeal to the citizens not to fall prey to the rumours about the spurt in the cases of missing children.

While denying such claims, we also warn rumour mongers of strict legal action for creating unnecessary panic and fear by misrepresenting data.

The safety of every child is of paramount importance to Delhi Police.

"Delhi Police is committed to serve 24x7 and making all out efforts to trace all missing persons and reunite them with distraught family members, at the earliest," they said in a statement released yesterday.

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Cheaper Copy Of Wegovy Pill By Hims & Hers Now Available For 49, Novo Nordisk Says It Will Take Legal Actions

Updated Feb 6, 2026 | 09:10 AM IST

SummaryHims & Hers’ $49 Wegovy copy has triggered legal threats from Novo Nordisk, which calls it unsafe and illegal compounding. The dispute hit drug stocks, raised safety and patent concerns, and spotlighted tensions over cheaper GLP-1 alternatives as weight-loss pill competition intensifies in the US.
Cheaper Copy Of Wegovy Pill By Hims & Hers Now Available For $49, Novo Nordisk Says It Will Take Legal Actions

Credits: iStock

Cheaper copy of Wegovy by Hims & Hers for $49 has drawn tensions, with Novo Nordisk now approaching to take legal actions. The pill by Novo Nordisk is sold for $149. In a statement, Novo said, "The action by Hims & Hers is illegal mass compounding that poses a significant risk to patient safety. Novo Nordisk confirmed that the company will take legal and regulatory actions to protect patients.

“Novo Nordisk will take legal and regulatory action to protect patients, our intellectual property and the integrity of the US gold-standard drug approval framework. This is another example of Hims & Hers’ historic behaviour of duping the American public with knock-off GLP-1 products, and the FDA has previously warned them about their deceptive advertising of GLP-1 knock-offs,” the statement said.

Read: Wegovy Pills Now Available At Your Pharmacies, Here's What To Know About Its Usage

Cheaper Copy Of Wegovy Pill: What Unveiled Afterwards?

After the cheaper copy of the pill was launched by Hims & Hers, shares of Novo Nordisk and rival Eli Lilly fell by 7%. Whereas, stock for Hims & Hers initially spiked after the announcement, but pared gains after Novo said that it would fight the rollout.

Hims & Hers was previously offering compounded semaglutide, the active ingredient in Novo Nordisk's popular weight loss drug Ozempic and Wegovy, in injectable format. The company has now extended to offer the oral version.

Cheaper Copy Of Wegovy Pill: How Much Does This Cost?

Hims & Hers said that the Wegovy copy pill cost $49 for the first month and $99 with a 5-month plan. While semaglutide's patent is protected in the US until 2032, however, Hims & Hers claim that the copies are 'personalized' and therefore legal.

“This compounded product uses a different formulation and delivery system than FDA-approved oral semaglutide,” Hims & Hers said. “This once-a-day pill has the same active ingredient as Wegovy and empowers providers to tailor treatment plans specifically for those who prefer to avoid needles or need smaller doses to help to balance side-effects,” it said.

Cheaper Copy of Wegovy Pill: Novo Nordisk Rejects Hims & Hers Claims

Novo Nordisk however, highlighted that it manufactures Wegovy pill by using SNAC technology. This technology helps in absorption when administered orally. Therefore, it is not clear how Hims & Hers copy formula could match that level of absorption.

Last year, Novo Nordisk and Hims & Hers partnered to offer weight loss jabs at a discounted price to telehealth company's customer. However, Novo Nordisk ended the collaboration just two months later, stating that Hims & Hers used 'deceptive' marketing that put patient safety at risk

Cheaper Copy of Wegovy Pill: Does Eli Lilly Have A Weight Loss Pill Yet?

While rival Eli Lilly does not have the weight loss pill yet, it is expected to launch orforglipron in the first half of this year. The pill is currently pending Food and Drug Administration approval.

Read: Eli Lilly Sends Weight-Loss Pill For Approval: Is Oral GLP-1 As Effective As The Injections?

“With the ... current legal backdrop, there is no reason why HIMS shouldn’t evaluate these launches for every subsequent weight loss product as the market continues to evolve,” Leerink analyst Michael Cherny said in a note to clients.

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TrumpRx Is Live: How Is It Changing US Healthcare System? Explained

Updated Feb 6, 2026 | 07:07 AM IST

SummaryTrumpRx, a new direct-to-consumer platform launched by President Trump, aims to cut US drug costs by directing cash-paying users to discounted medicines from select companies. Experts say benefits may be limited, especially for insured patients, though uninsured users could see savings potentially.
TrumpRx Is Live: How Is It Changing US Healthcare System? Explained

Credits: Wikimedia Commons and Canva

TrumpRx is live. President Donald Trump on Thursday announced the launch of TrumpRx, a direct-to-customer website that will lower prescription drug costs in the US.

As per the president, millions of Americans would save money through this platform. However, it is still unclear if all patients, especially those with insurance coverage will see more cost saving while using this website to buy their medicines.

TrumpRx is for people willing to pay cash and forgo insurance, which means people without or with limited coverage could benefit.

"You are going to save a fortune and this is also so good for overall health care," said Trump at the TrumpRx launching night on Thursday.

TrumpRx Is Live: How Does It Work?

TrumpRx Is Live: How Is It Changing US Healthcare System? Explained

TrumpRx does not sell drugs directly to American patients, rather acts as a central hub that points them to drugmakers who are offering discounts. For instance, Eli Lilly and Novo Nordisk were already offering their popular weight loss drugs at hefty discounts, TrumpRx would further give them discount coupons and redirect them to their website.

This means if someone clicks on Eli Lilly's Zepbound offer, it will send them directly to the company's platform, where the person must submit prescription details.

TrumpRx Is Live: Which Drugs Are Now Cheaper?

TrumpRx Is Live: How Is It Changing US Healthcare System? Explained

At launch, the site only featured medications from five companies, which are:

  • AztraZeneca
  • Lilly
  • EMD Serono
  • Novo Nordisk
  • Pfizer

However, as per a White House fact sheet, TrumpRx will list drugs from other companies "in coming months".

TrumpRx marks the government’s latest attempt to curb soaring prescription drug prices in the US, which are on average two to three times higher than in other developed countries and can be up to 10 times costlier than in some nations, according to public policy think tank Rand Corp.

TrumpRx Is Live: Is It Really Beneficial?

TrumpRx “doesn’t appear to be a one-stop solution” to high drug costs for most Americans, said Juliette Cubanski, deputy director of the Program on Medicare Policy at KFF, a health policy research organization. While cash-pay options may offer better value for people without insurance, it remains unclear how many individuals would actually benefit from TrumpRx, she noted.

“If someone can already access a medication through their insurance with a relatively affordable copay, there isn’t much added advantage to using the TrumpRx website,” Cubanski said.

She also pointed out that insured consumers who purchase medicines through direct-to-consumer platforms may find those purchases do not count toward their insurance benefits, meaning they do not help meet deductibles or out-of-pocket maximums.

At the same time, Cubanski said TrumpRx could play a role in improving access to certain drugs at lower prices, especially medications that are not widely covered by insurance in the US, such as obesity treatments. Medicare is set to cover weight-loss drugs for the first time later this year under agreements struck by Eli Lilly and Novo Nordisk with Trump, though many employers remain reluctant to include these medicines in their coverage.

However, she added that many other drugs expected to be offered on TrumpRx are already commonly covered by insurance, and several are also available as lower-cost generics from rival manufacturers.

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