Can Loneliness & Depression Harm Your Heart? Here's What Experts Say

Updated Feb 2, 2025 | 03:00 AM IST

SummarySubtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked. These signs play an important role in the early detection of heart diseases.
Depression and heart health

Depression and heart health (Credit: Canva)

Heart disease is often linked to high cholesterol, obesity, or lack of exercise. However, there is mounting evidence that suggests that mental health plays a crucial role in cardiovascular well-being. Stress, anxiety, and depression can silently strain the heart, increasing the risk of serious complications.

A recent study, published in Nature Human Behaviour, showed that loneliness has a significant impact on proteins present in a person's blood. For the study, researchers used data from more than 42,000 participants to explore whether the 9.3% who reported social isolation and 6.4% who reported loneliness had different levels of proteins in their blood compared with those who did not. The researchers then studied data that tracked the health of participants over an average 14-year period.

"We found around 90% of these proteins are linked to the risk of mortality," Dr Chun Shen, Fudan University in China, who is also the lead researcher said. "In addition, about 50% of the proteins were linked to cardiovascular disease, type 2 diabetes and stroke," he added.

Dr Shrey Kumar Srivastav, senior consultant at Sharda Hospital, said that subtle symptoms of heart disease, such as fatigue, shortness of breath, swelling in the lower legs, dizziness, and jaw pain, are often overlooked or attributed to stress and ageing. "Women, in particular, may experience atypical signs like extreme fatigue, indigestion, or upper abdominal pain instead of classic chest pain, leading to delayed diagnosis," he added.

Can Mental Health Issues Trigger Heart Diseases?

Chronic stress can trigger harmful cardiovascular effects, including elevated blood pressure, increased heart rate, and inflammation—key contributors to heart disease. Anxiety and depression further impact heart health by disrupting sleep patterns, raising stress hormone levels, and encouraging unhealthy habits like poor diet and inactivity.

Mental health issues like depression and anxiety have a profound impact on the heart. They don’t just affect emotions but can increase inflammation and put extra strain on the cardiovascular system, warns Dr Srivastav.

Certain risk factors, such as obesity and diabetes, disproportionately affect women, making them more vulnerable to heart failure with preserved ejection fraction (HFpEF). However, due to gender-specific symptom variations, heart disease in women often goes undiagnosed for longer.

Obesity is more prevalent in women than men and is a major risk factor for heart failure. Diabetes, too, has a greater impact on women’s heart health, yet diagnosis and treatment delays are common. Addressing this gap requires increasing awareness, training healthcare providers, and promoting early diagnostic tools,” explains Dr Srivastav.

How Can You Protect Your Heart?

A simple yet effective way to support heart health is by committing to a brisk 30-minute walk daily. Walking not only helps regulate blood pressure and manage weight but also improves circulation and reduces stress.

"Regular physical activity, paired with a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, significantly lowers cardiovascular risks," advises Dr Srivastav.

Heart disease can often go undetected until a major event occurs, making routine screenings essential.

- For women: Begin screenings around age 30 and continue with regular checkups.

- For men: Start screenings at age 35.

Health screenings, including blood pressure checks, cholesterol tests, and electrocardiograms (ECGs), are critical for early detection of silent heart conditions.

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Human H1N2v Swine Flu Case Detected In China: Should You Worry?

Updated Aug 19, 2026 | 04:50 PM IST

Summary​H1N2v differs from seasonal human H1N2 influenza. The “v” stands for variant, indicating a virus of swine origin. According to the US CDC, illness caused by variant influenza viruses has generally been mild, with symptoms similar to seasonal flu.
Human H1N2v Swine Flu Case Reported In China: Should You Worry?

Credit: iStock

China has reported a rare human case of H1N2v swine flu, underscoring the risk of zoonotic transmission and the importance of continued surveillance of swine-origin influenza viruses.

Swine flu is caused by type A influenza viruses that mainly infect pigs. Human infections are rare and usually occur after close contact with infected pigs. When these viruses infect humans, they are known as variant viruses.

H1N2v differs from seasonal human H1N2 influenza. The “v” stands for variant, indicating a virus of swine origin.

China Reports Human H1N2v Case

China reported its first human H1N2v infection in a 2-year-old boy from Yunnan province.

China notified WHO on February 3, 2026, after the infection was laboratory-confirmed on February 2. The child developed mild illness on January 20 and had reported exposure to domestic pigs before becoming ill.

A study by Chinese CDC researchers, published in Frontiers in Public Health on July 29, found:

  • The boy lived near pigs, chickens and pigeons.
  • A pig owned by his great-uncle died around the time the child became ill.
  • Influenza A was detected in samples from the child and the deceased pig.
  • Investigators considered the pig a plausible source, although the exact transmission route could not be established.
  • 30 close contacts were monitored; none tested positive or developed influenza-like illness.
  • No secondary infections were identified, with no evidence of human-to-human transmission.

No Evidence Of Sustained Human Spread

Dr Amit Prakash Singh, Consultant – Internal Medicine at CK Birla Hospital, Delhi, told HealthandMe that H1N2v is a swine-origin influenza virus that can occasionally infect humans, usually after exposure to infected pigs or contaminated environments.

“As no secondary cases or sustained human-to-human transmission were identified, this should not currently be viewed as a pandemic threat,” he said.

People with frequent pig exposure, young children, older adults, pregnant women and those with underlying health conditions may need greater caution, he added.

Prevention includes avoiding close contact with sick animals, practicing hand hygiene and respiratory precautions, and seeking medical attention for persistent or severe flu-like symptoms.

Previous H1N2v Cases

H1N2v infections have been reported sporadically in the US and Europe, particularly following exposure to pigs.

  • CDC surveillance lists 44 confirmed H1N2v infections in the US since 2010 through May 2026.
  • During the 2024–25 influenza season, one H1N2v infection was reported in an adult from Iowa. The patient was hospitalized and recovered.
  • CDC reported two H1N2v infections during the 2025–26 season by May 2026.

Human H1N2v infections remain rare. Greater concern would arise if there were evidence of sustained person-to-person transmission or changes that allow the virus to spread more efficiently among humans.

H1N2v Symptoms

According to the US CDC, illness caused by variant influenza viruses has generally been mild, with symptoms similar to seasonal flu. These can include:

  • Fever
  • Tiredness
  • Loss of appetite
  • Cough
  • Runny nose
  • Sore throat
  • Eye irritation
  • Nausea
  • Vomiting
  • Diarrhea

However, serious illness requiring hospitalization and, in some cases, resulting in death has also been reported.

How Is H1N2v Diagnosed And Treated?

Variant influenza A infection can be diagnosed through respiratory testing. Four antiviral drugs are recommended in the US for treating influenza: oseltamivir, peramivir, zanamivir and baloxavir, the CDC said.

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Harvard Agrees To Pay 53 Million Settlement After Former Morgue Manager Stole And Sold Donated Body Parts

Updated Aug 19, 2026 | 06:00 PM IST

SummaryThe civil lawsuit against Harvard University concerning theft and sale of parts from bodies donated for education and research is about to come to an end after the institution agreed to pay $53 million settlement.
Harvard Agrees To Pay $53 Million Settlement After Former Morgue Manager Stole And Sold Donated Body Parts

Credit: AI

Harvard University has agreed to pay $53 million (Rs 507 crore) to settle lawsuits brought by families whose loved ones donated their bodies to Harvard Medical School for education and research, only to have parts of those remains stolen and sold.

The settlement stems from Cedric Lodge's acts, the former morgue manager of Harvard Medical School, who was sentenced to eight years in prison after he pleaded guilty to stealing and selling human remains on the black market.

A Massachusetts court has granted preliminary approval to the settlement. The final approval is expected in December this year.

The case has not only raised disturbing questions about Lodge's actions, but also about how donated human remains are protected inside a reputed medical institution.

Deeper Glimpse Into The Case

Lodge worked at Harvard Medical School's morgue and had access to bodies donated to the school under their Anatomical Gift Program.

Federal prosecutors said that between 2018 and March 2020, instead of disposing remains according to the agreement, Lodge removed "heads, brains, skin and bones", and other body parts from donated cadavers after they had been used for teaching and research.

He allegedly transported the remains from the Harvard morgue in Boston to his home in New Hampshire, where he and his wife, Denise Lodge, sold them to buyers in different states. Some of the buyers subsequently resold the parts.

According to a statement from the US Attorney's Office, "At times, Cedric Lodge allowed [others] to enter the morgue at Harvard Medical School and examine cadavers to choose what to purchase."

Also read: Organ Donation: The Gift Of Life

When Did The Scandal Become Public?

The scandal came to light in 2023, when Lodge and several others were charged in the trafficking scheme. Lodge sentenced to eight years in federal prison in December 2025, while his wife, Denise Lodge, received a sentence of one year and one day for her involvement.

Other people who purchased remains from Lodge have also pleaded guilty and been sentenced. Katrina Maclean from Massachusetts, and Joshua Taylor from Pennsylvania, allegedly purchased body parts from Lodge.

According to the charging statement, in October 2020, Ms Maclean purchased dissected faces for $600 that she intended to have tanned into leather.

Ms Maclean owns a store called Kat's Creepy Creations. The business's social media page showed she specialised in up-cycling dolls into blood-soaked, horror novelties.

It is not confirmed if the cadaver parts were used in her products. The indictment alleges she stored and sold human remains at the store.

Mr Taylor allegedly bought several stolen body parts from Ms Lodge over the course of four years, worth more than $37,000. The indictment included a particularly grim reference to a PayPal memo for a purchase of $1,000 (£790) that allegedly read, "head number 7".

United States Attorney Gerard M. Karam said, "Some crimes defy understanding." He added, "The theft and trafficking of human remains strikes at the very essence of what makes us human."

George Q. Daley, Dean of the Faculty of Medicine at Harvard University, said he was "appalled to learn that something so disturbing could happen on our campus".

He said in a statement, "We are so very sorry for the pain this news will cause for our anatomical donors' families and loved ones, and Harvard Medical School pledges to engage with them during this deeply distressing time."

He also confirmed that Cedric Lodge was terminated on May 6.

Also read: World Organ Donation Day 2026: Too Old Or Too Sick To Donate Organs? Doctors Bust Key Myths

Families Questioned Harvard's Moral Responsibility

The criminal case against Lodge is separate from the civil lawsuits against Harvard. The families who donated the remains of their loved ones argued that Harvard had a responsibility to properly safeguard those bodies. Their lawsuits accused the university and medical school of negligence and breach of their duties toward donors and their families.

The case is particularly sensitive because body donation depends heavily on trust and respect. People who donate their remains generally do so with the expectation that they will be treated respectfully and used for legitimate medical education or research.

In October 2025, Massachusetts' highest court allowed the lawsuits against Harvard to proceed after an earlier dismissal, clearing the way for the settlement.

What Does The $53 Million Settlement Include?

The financial settlement will compensate families financially involved in the lawsuits. But Harvard has also agreed to certain non-financial compensation.

The institution will hold a live webinar with affected families and publicly acknowledge that Lodge's actions were “morally reprehensible” and inconsistent with Harvard's standards for treating anatomical donors and their loved ones.

Harvard also plans to create an annual scholarship for medical students, beginning in the 2027-28 academic year, in honour of people who donated their bodies to the school's Anatomical Gift Program.

Harvard Medical School Dean George Daley and Dean for Medical Education Bernard Chang said the settlement would allow the university and families to avoid prolonged litigation, while acknowledging the devastating impact of the scandal.

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₹5 Crore Fake Medicine Racket Busted Near Bengaluru: Why Counterfeit Drugs In ICUs Are A Major Health Risk

Updated Aug 19, 2026 | 03:00 PM IST

SummaryHealth officials recently nabbed a fake medicine racket in Karnataka, which sparked concerns about dangers of counterfeit drugs inside intensive care units (ICUs).
₹5 Crore Fake Medicine Racket Busted Near Bengaluru: Why Counterfeit Drugs In ICUs Are A Major Health Risk

Credit: AI

A major counterfeit medicine racket has been busted near Bengaluru, with authorities seizing spurious drugs worth around ₹5 crore from a facility near the Bidadi toll gate.

But the investigation has raised an even bigger concern. Some of the fake drugs may also have entered hospitals, pharmacies and even intensive care units (ICUs).

Karnataka Health Minister U T Khader said the drugs were allegedly relabelled using the names of multinational pharmaceutical companies.

The Food Safety and Drug Administration's drug wing carried out the operation on August 18. Officials suspect the racket could be connected to a wider network spanning multiple states, with counterfeit pharmaceuticals sourced from different places including Himachal Pradesh and Telangana.

Why Are Fake Drugs Dangerous In ICUs?

According to officials, the medicines were allegedly relabelled with the branding of known pharma companies, making counterfeit products appear genuine. This is particularly concerning as fake medicines could become difficult to identify and eliminate simply by examining the packaging.

Authorities are now looking into where these medicines came from, how they got into the supply chain, and which hospitals or pharmacies may have received them. It has not been reported that any hospital has actually administered the fake drugs to the patients.

Counterfeit medicines are always a major public health concern, but the consequences can be particularly severe in an ICU.

Critically ill patients often depend on medicines that have to work quickly at precise doses. Drugs used in intensive care can include antibiotics, medicines to control blood pressure, sedatives, pain medicines and drugs that support organ function.

Also read: From Liquor to Dabur to VKC Nuts, FSSAI Crackdown Puts Food Safety in Focus: Why It Matters

If a counterfeit product contains too little, too much, the wrong ingredient or no active ingredient at all, treatment can fail at the moment a patient needs it most.

For instance, a fake antibiotic may contain insufficient active medicine. In a critically ill patient with a serious infection, that could mean the infection continues to worsen while doctors believe the patient is receiving appropriate treatment. This could delay the correct course of treatment, leading to potential complications.

The opposite problem is also a possibility. An incorrectly formulated medicine could lead to toxicity, allergic reactions, organ damage, or other complications.

The Bigger Problem Of Fake Drugs In The Country

India's drug regulators regularly issue alerts about medicines that fail quality tests, while the Indian Pharmacopoeia Commission's Pharmacovigilance Programme of India publishes drug safety alerts and regulatory information. The Centre has also been strengthening pharmaceutical traceability and regulatory oversight.

Earlier this month, the government notified amendments to the Drugs Rules that allow regulatory authorities to debar applicants who submit misleading, fake or fabricated documents or information to get their drugs approved.

But the Bengaluru case highlights a different challenge. Even when legitimate medicines are properly regulated, counterfeit products can infiltrate the supply chain. Health Minister Khader said the suspected racket could be part of a larger national network, making the investigation particularly crucial.

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