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Whenever you are feeling anxious or stressed, the first thing you are told to do is control your breath. There are many different breathing techniques that you can try, like yoga breathing practices like Ujjayi breath, alternate nostril breathing, and deep diaphragmatic breathing.
Diaphragmatic breathing, often called belly breathing, is a simple way to use your diaphragm muscle to breathe more effectively. The Cleveland Clinic explains that the diaphragm is a dome-shaped muscle at the bottom of your lungs. When you inhale, it moves down, making space for your lungs to fill with air. Your belly pushes out as this happens. When you exhale, the diaphragm moves up, pushing the air out. This type of breathing is different from chest breathing, where only your chest moves. You can do this breathing technique anywhere, anytime, and no one will even notice. It's a great tool for calming down quickly.
The reason why this is the go-to response for stressed people is because when you are stressed, your breathing becomes fast paced. The Cleveland clinic explains that stress triggers a fight or flight response in your body. Your body goes into survival mode as it thinks it is in danger. Some symptoms of this include, racing heart rate and blood pressure increase, this means that you are breathing quickly and heavily in order to move nutrients and oxygen into important muscles of your body.
Belly breathing has many good things about it. It helps calm your nervous system, which is important when you're stressed. It activates a nerve called the vagus nerve, which helps your body relax. When you breathe slowly, your heart rate also slows down, and your body feels less stressed. It helps you control your feelings, like anxiety and fear, so you can think more clearly. This kind of breathing also helps your lungs work better by taking in more oxygen. It can even help you sleep better because it calms your mind. By practicing regularly, you can feel calmer and more relaxed every day.
Certain conditions like Chronic Obstructive Pulmonary Disease (COPD) do make it difficult to work the diaphragm effectively. Your lungs rise and fall naturally, however with COPD air often becomes trapped in your lungs. Make sure you speak to a healthcare professional in case you are facing any difficulties while breathing.
To start, find a comfy spot. You can lie down with your knees bent or sit with your feet flat on the floor. Put one hand on your belly and the other on your chest. Now, breathe in deeply through your nose. Let your belly push out while your chest stays still. Hold your breath for a moment. Then, slowly breathe out through your nose or with your lips a little bit closed, letting your belly go back in. Do this four to six times, slowly and deeply. As you get better at it, you can do more breaths. Practice this every day, even when you're not feeling stressed, to feel calmer all the time.
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Smartwatches and fitness trackers are widely used for counting daily steps and tracking workouts by millions. But the World Health Organization (WHO) is now seeking to task these wearables with bigger responsibilities. The global health body has issued proposals for wearable devices that could help countries measure physical activity and sedentary behaviour across populations.
In a notice published on November 8, WHO invited researchers, health authorities, technology developers and other stakeholders to review a draft Target Product Profile (TPP) for wearable devices worn on wrists. The aim is to ascertain what these devices should be capable of measuring before they are incorporated into national and subnational public health monitoring systems.
The proposal will remain open until December 6, 2026. WHO will use the feedback to revise and finalise the document and inform future implementation guidance.
Physical inactivity is a major risk factor for non-communicable diseases, including cardiovascular disease, type 2 diabetes and certain cancers. Sedentary behaviour, which involves spending prolonged periods sitting is also the cause of various adverse health outcomes.
Countries currently rely heavily on surveys to understand how physically active people are. However, these often depend on people reporting their own activity, which can lead to inaccurate data.
Wearable devices could provide a more objective way to collect information over a certain period of time. Instead of relying entirely on questionnaires, health authorities could use data from these devices to understand how much people move, how long they remain sedentary and how activity patterns vary across different population groups.
WHO says wearable technology could complement existing surveillance methods as countries work towards improving global physical activity targets.
Also read: Weight Loss Without Extreme Diets: What Sustainable Medical Weight Management Looks Like
The draft TPP outlines minimum specifications for smartwatches intended for population-level monitoring. It considers what makes a device suitable for collecting data across different populations.
The proposed framework covers:
WHO is interested in feedback on whether the specifications proposed are practical and relevant to countries with limited resources.
Although such wearables are widely available, their measurements are not interchangeable. Different manufacturers use different sensors, algorithms and methods to calculate steps, activity levels and sedentary time. As a result, two devices worn by the same person may produce different estimates.
A systematic review published in npj Digital Medicine in January 2026 examined 82 studies evaluating Apple Watch measurements across 14 health metrics. It found that measurement accuracy varied depending on the metric and testing conditions. While heart-rate measurements showed good overall agreement, step counts had moderate accuracy and energy expenditure data was inconsistent too.
This illustrates the need for standardisation. If countries use different devices and measurement methods, comparing physical activity data across populations becomes needlessly challenging.
WHO's proposed framework is intended to address these differences by identifying the device characteristics and protocols needed for consistent data collection.
Cost, access, privacy and digital literacy remain important challenges when it comes to implementing WHO's proposal. People without smartphones, reliable internet access or the ability to buy wearable devices could be underrepresented.
There are also questions about how personal movement data would be stored, shared and protected. Governments would need clear safeguards to ensure that participation is voluntary, data is handled responsibly and findings represent the wider population.
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Mazdutide, an experimental weight-loss drug, could soon join the ever-expanding market of GLP-1 medications. The results from a recent clinical trial funded by Eli Lilly has found that mazdutide has shown an average reduction of 18.1% in body weight over 32 weeks. The trial was published in The Lancet Diabetes & Endocrinology.
The findings have drawn attention because the experimental drug produced significant weight loss in less than eight months, establishing its position among existing medicines like Wegovy.
However, the findings come from a phase 2 trial involving 179 participants. Its comparison with existing players like Wegovy are yet to be done formally.
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Published in November 2026, the randomised, double-blind, placebo-controlled trial evaluated mazdutide in 179 overweight or obese adults with overweight but without type 2 diabetes.
Participants, who were recruited from 24 centres in the United States, received the once-weekly injections of different doses of the drug or a placebo. At 32 weeks, the average weight changes were:
The study also reported further weight reductions by week 48, suggesting that weight loss had not reached its maximum by the primary assessment.
However, tolerability of the drug drew attention too. Gastrointestinal problems, including nausea, vomiting and diarrhoea, were among the most common side effects.
Around 20% of participants receiving the highest 16 mg dose quit the treatment because of adverse events, primarily gastrointestinal disorders.
Also read: Australia Approves First GLP-1 Weight Loss Pill: How It Works & Who Is Eligible
Mazdutide works differently from semaglutide, the active ingredient in Ozempic and Wegovy. It activates two hormone receptors involved in regulating appetite and metabolism: glucagon-like peptide-1 (GLP-1) and glucagon.
GLP-1 helps regulate blood sugar, which slows down emptying of the stomach and increases feelings of fullness, which can reduce food intake.
Glucagon is another hormone involved in regulating blood glucose and energy metabolism. By activating glucagon receptors along with GLP-1 receptors, mazdutide can affect energy expenditure and metabolism in addition to regulating appetite.
This dual action distinguishes it from semaglutide, which primarily targets the GLP-1 receptor.
Also read: GLP-1 Drugs May Be More Effective Than Metformin At Preventing Diabetes: Study
Ozempic and Wegovy contain the same active ingredient, semaglutide, but have different approved uses and dosing.
Ozempic is primarily prescribed for type 2 diabetes and certain cardiovascular and kidney conditions, while Wegovy is approved for weight management.Here is how the trial results compare:
Mazdutide 16 mg showed 18.1% weight reduction in 32 weeks. Wegovy 2.4 mg showed 14.9% in 68 weeks.
In the STEP 1 trial, published in The New England Journal of Medicine in 2021, participants with overweight or obesity who received semaglutide 2.4 mg lost an average of 14.9% of their body weight over 68 weeks. Participants did not have diabetes.
Although mazdutide's 18.1% result seems higher than the 14.9% reported with Wegovy, the comparison has limitations. The trials differed in duration, participant characteristics, doses and study design. A direct head-to-head trial would be needed to establish which treatment produces greater weight loss.
Mazdutide has also been studied in China. In the phase 3 GLORY-2 trial, participants receiving 9 mg lost an average of 16.65% of their body weight over 60 weeks, compared to 1.50% in the placebo group.
Its recent findings are promising but it is too early to call mazdutide more effective than existing treatments. The US study was a relatively small phase 2 trial, and its highest dose led to a high rate of discontinuation due to adverse events. Larger phase 3 trials are important to establish its long-term effectiveness, safety and tolerability.
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"Losing weight isn't about obsessing over diets or rushing to shed pounds."
It is about understanding the reasons behind why a person weighs as much as they do and adopting healthy habits to create long-term success. From an endocrinologist's viewpoint, managing weight involves a thorough approach. Factors such as hormonal imbalances, insulin resistance, thyroid conditions, polycystic ovary syndrome (PCOS), some medications, genetics, and lifestyle choices can all affect body weight. As a result, a single diet or exercise routine may not be equally effective for everyone.
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Eating a balanced diet high in nutrients is a key principle to weight control. It's advised not to cut out all food groups or eat extreme low amounts of calories, but ensure that your diet includes moderate portions, lots of protein, fibre-dense, foods, veggies, fruits, and good fats. Participating in a regular exercise programme with cardio exercises and resistance training can boost your metabolic health.
Sleep and behaviour are equally vital. Poor sleep can impact hunger hormones and it can cause cravings, then add stress and emotional eating maintenance can be tricky. Keeping to a sleep routine, managing stress and setting realistic targets will aid in developing a lasting habit.
Assessment of diet there are certain circumstances, when medical assessment would be the next step, such as significant unexplained weight gain, the failure to lose weight despite an effort, and if there is a presence of other manifestations/diseases like diabetes, high blood pressure, hormonal problems etc. A personalised evaluation is a review of medical history, medication, and relevant investigations and metabolic risk factors.
Your healthcare professional may recommend prescription weight-management medication to use beyond nutrition and lifestyle management, where your weight management plan is based on your BMI, related health conditions and clinical management. Your healthcare professional will need to monitor treatment with medication. You may also be considered for bariatric surgery where clinically indicated.
It's not about hitting the scales at a lesser weight; the aim should be to achieve good metabolic health, physical fitness and quality of life. The fact is that weight loss is a slow journey, and even small, sustainable weight loss can bring significant health gains. A custom program, ongoing assessment and adequate support will beat fad diets every time."
By Dr Hetashvi Gondaliya, Diabetes & Endocrinology, CK BIRLA HOSPITALS Jaipur
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