The global obesity epidemic, affecting over one billion people worldwide, is largely driven by eating behaviors. Appetite, influenced by both intrinsic and environmental factors, plays a crucial role in weight management. A recent study how exercise affects appetite perception in obese males, shedding light on the physiological mechanisms behind hunger suppression post-exercise.
While exercise is well-known for its benefits in weight management, its direct impact on appetite control has remained a subject of debate. Appetite is regulated by a complex network of gastrointestinal and neurohormonal signals, including hormones like ghrelin, leptin, interleukin 6 (IL-6), and neuropeptide Y (NPY). These hormones influence hunger levels, satiety, and energy balance.
The study published in Physiological Reports examines investigated how moderate continuous aerobic exercise (MICE) alters these hormone levels in obese men, ultimately affecting their hunger perception. The findings reveal that certain myokines and cytokines shift dynamically post-exercise, potentially reducing appetite and offering a promising strategy for weight management.
The study found that after exercise, there was a significant increase in IL-6 and irisin levels in the exercise group compared to those who remained sedentary. These elevated concentrations persisted for an hour after working out. IL-6 has been associated with regulating metabolism and enhancing fat oxidation, while irisin plays a role in converting white fat into more metabolically active brown fat.
Conversely, the study reported a decrease in neuropeptide Y (NPY) levels, a key neurotransmitter responsible for stimulating appetite. The decline in NPY levels post-exercise suggests a temporary suppression of hunger, supporting the idea that exercise can curb cravings. However, the study did not observe significant changes in IL-7 or leptin levels, two other hormones involved in appetite regulation.
Ghrelin, often called the “hunger hormone,” stimulates appetite by increasing activity in specific areas of the brain. Individuals with higher ghrelin levels generally find it harder to lose weight because their bodies signal hunger more frequently.
Research suggests that dieting can lead to an increase in ghrelin levels, making weight loss challenging. Certain medical conditions, such as Hashimoto’s thyroiditis, Prader-Willi syndrome, anorexia nervosa, and bulimia nervosa, are also linked to elevated ghrelin levels, complicating appetite regulation further.
While exercise has clear benefits, the findings should be interpreted with caution. He pointed out that the study had a small sample size, making it difficult to draw definitive conclusions.
Moreover, he highlighted the challenges faced by obese individuals in maintaining an intensive exercise routine. While exercise-induced appetite suppression is promising, consistently engaging in high-intensity workouts may be unrealistic for those who struggle with mobility or fitness levels. More extensive studies are needed to determine the optimal exercise duration and intensity for effective appetite suppression.
Besides exercise, there are several strategies individuals can use to naturally suppress their appetite and improve satiety:
Increase Protein Intake: Protein-rich foods, such as lean meats, legumes, and dairy, promote feelings of fullness and reduce hunger.
Stay Hydrated: Drinking water before meals can help control portion sizes and prevent overeating.
Opt for Fiber-Rich Foods: Whole grains, vegetables, and fruits high in fiber take longer to digest, keeping you full for longer.
Reduce Simple Carbohydrates and Sugars: Simple carbs and sugars cause rapid spikes and crashes in blood sugar levels, leading to increased hunger.
Prioritize Sleep: Poor sleep disrupts hunger-regulating hormones, making it harder to control cravings.
Manage Stress: Chronic stress increases cortisol levels, which can lead to overeating and weight gain.
The study’s findings indicate that moderate exercise can temporarily suppress appetite by altering key hormones. While more research is needed to refine the details—such as optimal workout duration and intensity—this insight adds to the growing body of evidence supporting exercise as a tool for appetite regulation and weight management.
For individuals looking to curb cravings and maintain a healthy weight, incorporating a well-balanced diet alongside regular exercise remains the most sustainable approach. Future studies focusing on larger populations and long-term effects could provide deeper insights into how exercise can be optimized for appetite control, making it an effective strategy in combating obesity.
Exercise alone is not a magic solution for weight loss, but its impact on appetite hormones presents a promising avenue for managing hunger and energy balance. As research continues to evolve, it becomes increasingly clear that integrating physical activity with mindful eating habits can play a vital role in achieving and maintaining a healthy lifestyle.
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Garba season is back, bringing hours of energetic dancing. While this aerobic activity naturally raises your heart rate, prolonged, high-intensity sessions can strain the cardiovascular system. In 2023, 10 people died within 24 hours while performing Garba.
So, how do you distinguish a normal exercise response from a warning sign?
Dr. Anesh Jain, Cardiologist, Ruby Hall Clinic, Pune, told HealthandMe that two factors drive a faster heartbeat during Garba:
Also read: Weekend Workouts: Why Sudden Intense Exercise May Put Stress on Your Heart
Dr. Nimit Shah, Consultant Interventional Cardiologist, Saifee Hospital, Mumbai, told HealthandMe that the heart beats faster during Garba to supply oxygen-rich blood to working muscles.
A normal exercise response typically involves:
However, a sudden or irregular heartbeat, or one that remains unusually fast despite rest, should not be ignored.
Dr. Anesh advised stopping immediately if you experience:
Chest pain, severe breathlessness or fainting requires emergency medical attention.
Read More: Strong Enough for HYROX, But Is Your Heart Fit Enough?
Several factors can increase the risk of complications:
“Prolonged dancing, dehydration, excessive sweating and inadequate food intake can put stress on the body,” Dr. Nimit said.
People with heart conditions, high blood pressure, diabetes or a history of abnormal heart rhythms should take extra precautions.
Dr. Nimit recommended warming up, gradually increasing dance intensity, taking regular breaks and staying hydrated. Avoid prolonged dancing in hot, crowded venues.
Other precautions include:
If your heartbeat feels unusually fast or irregular:
Do not push through symptoms or rely on hydration and breathing exercises to manage possible cardiac warning signs.
The experts advised that Garba should be a celebration, not a test of endurance. Recognizing warning signs, taking breaks and respecting your limits can help you dance safely.
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If you are trying to lose weight loss for a long time, it can become a cycle of strict diets, missed targets and constant frustration. Actor Melissa McCarthy says changing her relationship with weight, rather than constantly trying to control it, helped her approach the weight loss process differently.
In a recent interview with CBS Mornings, the Bridesmaids star reflected on how she stopped fixating on her weight. “I finally said [to myself], 'Oh, for God's sake, stop worrying about it,' and it may be the best thing I've ever done,” she said.
“I truly stopped worrying about [my weight]. I stopped over-analyzing, over-thinking, over-doing anything.” McCarthy added, “I just stopped constantly being worried about it, and I think there's something to kinda loosening up and not being so nervous and rigid about it that, bizarrely, has worked.”
McCarthy's weight loss mindset sheds light on a less restrictive, more sustainable approach can help people break the cycle of repeated dieting and weight regain, also known as yo-yo dieting.
Also read: Strong Enough for HYROX, But Is Your Heart Fit Enough?
Yo-yo dieting, also known as weight cycling, refers to a constant process of repeatedly losing weight and regaining it. People may turn to restrictive diets for quick results, only to find that it is difficult to maintain over time and end up regaining all the lost weight.
Weight loss triggers certain changes in appetite and energy expenditure that can make maintaining the new weight challenging. Hunger may shoot up, while the body may expend less energy than expected, making regaining lost weight more likely.
Extremely restrictive eating plans can also be difficult to sustain alongside work, family responsibilities and social life. When a diet becomes too demanding, people may give up and return to previous eating patterns, sometimes interpreting weight regain as a personal failure rather than a sign that the approach was unsuitable for them.
McCarthy has previously spoken about moving away from extreme approaches. In a 2018 interview with The Breakfast Club, she said, “If I can de-stress and just do it slower and stop constantly trying to be on something.” She added that this approach “actually worked better instead of being like, ‘I'm gonna not do this and do this and only drink this.’”
She also said, “I'm just gonna mellow out, give myself a break.”
According to a few studies, yo-yo dieting has also been associated with health problems like changes in blood pressure and cholesterol. However, a 2024 review of 23 studies found that most available evidence did not show consistent adverse effects of weight cycling itself on body composition or resting metabolic rate.
A 2026 review published in The Lancet Diabetes & Endocrinology similarly concluded that current evidence does not strongly support a link between weight cycling itself and adverse changes in body weight, body composition or metabolic function.
This does not mean repeated weight loss and regain is irrelevant to health and overall fitness. It means the effects should not automatically be attributed to weight fluctuations alone, and people should not be discouraged from making another attempt at improving their health.
A less rigid approach may make weight management more manageable by reducing the constant pressure. Setting realistic goals, maintaining eating patterns that can be maintained over time and allowing flexibility may help avoid the all-or-nothing thinking that often comes with extremely restrictive dieting.
However, McCarthy's personal experience does not prove that changing one's mindset alone causes weight loss or prevents weight regain. Weight management is influenced by genetics, hormones, medications, sleep, stress, environment and other factors.
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HYROX has suddenly become a fresh fitness challenge for anyone willing to test the limits of their strength and endurance. The typical gym session will soon be swapped out with a HYROX race, a hybrid of running and brutal functional fitness movements that have you shifting constantly between cardio and muscular efforts.
Being able to lift heavy weight, run for kilometers, or knock out the crazy gym session doesn't guarantee the heart is ready to match that level of high-intensity work. An individual having great strength and endurance doesn't guarantee he/she has a healthy heart.
The significance of this difference is that cardiovascular disease is still a huge problem. According to the WHO, as many as 19.8 million people died from cardiovascular diseases worldwide in 2022, representing approximately 32% of all deaths. In India, the disease is also a significant cause of death; WHO states that 27% of deaths in India are caused due to CVDs, and it is estimated that around 220 million people in India suffer from high blood pressure.
It does not mean that people should be scared of hard exercise. Exercise is a vital component of heart health. The question is, is the individual adequately prepared for the intensity of effort they are undertaking?
Also read: Is 'Hyrox' Challenge Worth The Hype Or Just Another Fitness Trend?
People who are starting a program of vigorous exercise should be familiar with the symptoms of distant chest pain, abnormal breathlessness, fainting or dizziness, palpitations or irregular heartbeats, or abrupt decrease in exercise capacity.
If you have a personal or family history of early cardiac disease, known hypertension, diabetes, high cholesterol, smoking, obesity or prior cardiac disease, it would also be worth discussing with your physician prior to high intensity training. Most importantly, we emphasise that there is no universal cardiac screening test that every participant of HYROX requires. Cardiovascular screening should be risk stratified and individualized.
Sometimes just taking your blood pressure and examining you will be sufficient. A doctor might choose to do additional tests – eg, an ECG or exercise stress test – if you have symptoms and/or risk factors and/or other diseases, especially if you are 40 years or older. Additional tests may also include images of your heart.
The European Society of Cardiology's sports-cardiology guidance recommends on risk determination before strenuous physical activity, but not on the use of the same testing algorithm for all. An evaluation with a clinical assessment, ECG, and exercise testing may be recommended for adults who are not physically active or have a high cardiovascular risk for a planned high-intensity exercise.
Don't confuse fitness with cardiovascular clearance One may have very strong muscle and not be aware that he or she has an unrecognized risk factor for cardiac health. Alternatively, a person with a known cardiac condition may safely perform a monitored exercise program with appropriate testing and management. The goal is not to keep you from any additional HYROX or heavy training, but only to Know what your heart is capable of and your risk factors, warning signs and symptoms.
Strength is one element of fitness. But before you question whether you have enough strength to finish the next workout, here's a question for you: Is your cardio ready?
By Dr. Rajat Kar, Consultant - Adult Cardiology, Narayana Hospital, Howrah
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