The global obesity epidemic, affecting over one billion people worldwide, is largely driven by eating behaviors. Appetite, influenced by both intrinsic and environmental factors, plays a crucial role in weight management. A recent study how exercise affects appetite perception in obese males, shedding light on the physiological mechanisms behind hunger suppression post-exercise.
While exercise is well-known for its benefits in weight management, its direct impact on appetite control has remained a subject of debate. Appetite is regulated by a complex network of gastrointestinal and neurohormonal signals, including hormones like ghrelin, leptin, interleukin 6 (IL-6), and neuropeptide Y (NPY). These hormones influence hunger levels, satiety, and energy balance.
The study published in Physiological Reports examines investigated how moderate continuous aerobic exercise (MICE) alters these hormone levels in obese men, ultimately affecting their hunger perception. The findings reveal that certain myokines and cytokines shift dynamically post-exercise, potentially reducing appetite and offering a promising strategy for weight management.
The study found that after exercise, there was a significant increase in IL-6 and irisin levels in the exercise group compared to those who remained sedentary. These elevated concentrations persisted for an hour after working out. IL-6 has been associated with regulating metabolism and enhancing fat oxidation, while irisin plays a role in converting white fat into more metabolically active brown fat.
Conversely, the study reported a decrease in neuropeptide Y (NPY) levels, a key neurotransmitter responsible for stimulating appetite. The decline in NPY levels post-exercise suggests a temporary suppression of hunger, supporting the idea that exercise can curb cravings. However, the study did not observe significant changes in IL-7 or leptin levels, two other hormones involved in appetite regulation.
Ghrelin, often called the “hunger hormone,” stimulates appetite by increasing activity in specific areas of the brain. Individuals with higher ghrelin levels generally find it harder to lose weight because their bodies signal hunger more frequently.
Research suggests that dieting can lead to an increase in ghrelin levels, making weight loss challenging. Certain medical conditions, such as Hashimoto’s thyroiditis, Prader-Willi syndrome, anorexia nervosa, and bulimia nervosa, are also linked to elevated ghrelin levels, complicating appetite regulation further.
While exercise has clear benefits, the findings should be interpreted with caution. He pointed out that the study had a small sample size, making it difficult to draw definitive conclusions.
Moreover, he highlighted the challenges faced by obese individuals in maintaining an intensive exercise routine. While exercise-induced appetite suppression is promising, consistently engaging in high-intensity workouts may be unrealistic for those who struggle with mobility or fitness levels. More extensive studies are needed to determine the optimal exercise duration and intensity for effective appetite suppression.
Besides exercise, there are several strategies individuals can use to naturally suppress their appetite and improve satiety:
Increase Protein Intake: Protein-rich foods, such as lean meats, legumes, and dairy, promote feelings of fullness and reduce hunger.
Stay Hydrated: Drinking water before meals can help control portion sizes and prevent overeating.
Opt for Fiber-Rich Foods: Whole grains, vegetables, and fruits high in fiber take longer to digest, keeping you full for longer.
Reduce Simple Carbohydrates and Sugars: Simple carbs and sugars cause rapid spikes and crashes in blood sugar levels, leading to increased hunger.
Prioritize Sleep: Poor sleep disrupts hunger-regulating hormones, making it harder to control cravings.
Manage Stress: Chronic stress increases cortisol levels, which can lead to overeating and weight gain.
The study’s findings indicate that moderate exercise can temporarily suppress appetite by altering key hormones. While more research is needed to refine the details—such as optimal workout duration and intensity—this insight adds to the growing body of evidence supporting exercise as a tool for appetite regulation and weight management.
For individuals looking to curb cravings and maintain a healthy weight, incorporating a well-balanced diet alongside regular exercise remains the most sustainable approach. Future studies focusing on larger populations and long-term effects could provide deeper insights into how exercise can be optimized for appetite control, making it an effective strategy in combating obesity.
Exercise alone is not a magic solution for weight loss, but its impact on appetite hormones presents a promising avenue for managing hunger and energy balance. As research continues to evolve, it becomes increasingly clear that integrating physical activity with mindful eating habits can play a vital role in achieving and maintaining a healthy lifestyle.
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Mobility and independence are two things that keep people healthy, however, with age, as bones weaken and muscle is lost, elderly become more dependent. This condition is called sarcopenia, or age-related muscle loss. India is finally focusing on this and have now new guidelines to warn people against it.
The Geriatric Society of India released country's first 'Indian Guidelines for the Evaluation and Management of Sarcopenia'. These guidelines are a combination of recommendations by experts across multiple specialties, including geriatric medicine, orthopedics, endocrinology, physiotherapy and nutrition. These guidelines aim to help doctors detect and treat muscle loss early. The aim is to not let elderly compromise with their independence.
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Sarcopenia literally translates to 'loss of flesh'. Medically, it refers to gradual decline in muscle mass, strength and physical function with aging. While it is often overlooked, it is also the major reason for many fractures and hospitalizations of older adults, and sometimes, even death.
India is expected to have around 319 million people aged over 60 by 2050, which is one-fifth of the population. It could be concerning as they are at risk of sarcopenia. Studies have also shown that the number has increased from 8-18 per cent to 25-40 per cent adults, especially hospitalization cases. Experts point out that those with chronic diseases like diabetes are at a higher risk.
Dr OP Sharma, who led guidelines said that muscle health is most important for healthy aging. "Strength preserves dignity. Early detection saves independence," he said. Dr Sharma also noted that the sedentary lifestyle, poor nutrition and chronic illnesses are accelerating this condition among seniors.
The guidelines also advise doctors to look for warning signs in patients, which include weak grip strength, slower walking speed, or difficulty getting up from a chair. There are also screening tools like SARC-F questionnaire, which could help identify those at risk.
The ray of hope here is that sarcopenia could be prevented or slowed that too with simple lifestyle changes.
Doctors are also advising to eat a balanced diet, which includes protein, fats, green vegetables, and pulses. Dr Raju Vaishya of Indraprastha Apollo Hospitals said, "India is a sarcopenic nation". He pointed that everyone needs to be aware about muscle health, however this awareness remains low in the country.
Dr Randeep Guleria said the guidelines aim to brings muscle health into routine medical care. "They bridge science with clinical wisdom, making sarcopenia visible in everyday practice."
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A new Nature Human Behaviour (2026) study suggests that single-session psychological exercises lasting less than 10 minutes can lead to measurable decreases in depression symptoms even one month later.
Depression is one of the most common mental health disorders in the world. Every year, hundreds of millions of people suffer from depression, and many are unable to get therapy because of cost, stigma and the dearth of mental-health professionals.
Symptoms include excessive sadness, depression often includes fatigue, changes in appetite, sleep disturbances, difficulty concentrating and feelings of hopelessness. Treatment requires professional guidance for diagnosis and management.
All the brief interventions took less than 10 minutes to complete and were designed to teach practical coping skills that are commonly used in psychotherapy. Some exercises helped participants to reframe negative thoughts, while others focused on motivation, goal-setting or making sense of things by helping others. Participants completed surveys measuring their well-being immediately after the session and again one month later.
The results were striking: while many exercises boosted motivation and hope immediately, two interventions - Interactive Cognitive Reappraisal and Finding Focus - showed measurable reductions in depression symptoms even after a month. On average, participants experienced about a four percent greater reduction in depression scores compared with the control group.
Although the improvement may appear small, researchers note that brief, scalable interventions could reach millions of people who currently lack access to mental-health care as they can be completed in a few minutes and delivered online, these exercises may allow people to take initial steps toward better mental health, especially those waiting for professional help or unwilling to ask for help.
The scientists also stressed that these activities are not intended to substitute for therapy, but should be seen as readily available tools to help with emotional health.
Previous research also shows that a quick burst of activity can make you feel better from other research too. A British Journal of Health Psychology 2024 study found that just 10 minutes of daily mindfulness practice significantly improved well-being and reduced symptoms of depression and anxiety among more than 1,200 participants from 91 countries.
Similarly, the US National Institutes of Health (2019) reviews suggest that the physical activity itself may help improve mood and depressive symptoms, strengthening the relationship between movement and mental health.
Collectively, these findings suggest that even small doses of mental or physical activity may lead to psychological benefits.
Depression can make people feel trapped and out of control. The good news of the new research is that it suggests that big changes aren’t always necessary to move forward.
Sometimes, doing a small task, like spending 10 minutes learning a new coping skill or doing a quick mental exercise, is enough to change the way you think and gradually improve mood.
As researchers investigate these brief interventions, one thing is becoming clear: when it comes to mental health, few minutes matter more than we think.
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British broadcaster Gabby Logan has revealed that her 20-year-old daughter Lois has been diagnosed with polycystic ovary syndrome (PCOS), a hormonal condition that may require her to step back from high-intensity endurance sport, including extreme long-distance running.
Speaking on her Mid-Point podcast, Logan said the diagnosis came after medical consultations about her daughter’s health and training. During the appointment, a specialist advised Lois to avoid “extreme running,” prompting mixed emotions in the family, concern about the condition, but also relief about scaling back punishing physical goals.
PCOS is one of the most common endocrine disorders in women of reproductive age, affecting an estimated 8–13 per cent globally. It occurs when the body produces higher levels of androgens (male-type hormones) and often involves insulin resistance.
The condition can cause irregular periods, acne, excessive hair growth, weight changes and fertility challenges. Many patients also have difficulty regulating blood sugar, increasing long-term risks of type 2 diabetes and heart disease.
While exercise is widely recommended as a cornerstone of PCOS management, helping improve insulin sensitivity, metabolism and mood, specialists say the type and intensity of exercise matter.
Doctors cautioned Lois against extreme endurance events such as half-marathons because prolonged, high-intensity training can significantly elevate cortisol, the body’s primary stress hormone.
In people with PCOS, hormonal balance is already fragile. Persistently high cortisol may:
In other words, although movement is beneficial, chronic physical stress can sometimes counteract the hormonal stability patients are trying to restore.
Moderate-intensity exercise, brisk walking, strength training and shorter runs, is generally considered more supportive for hormone regulation than sustained high-intensity endurance workloads.
Logan previously completed the London Landmarks Half-Marathon with Lois in 2024, describing the preparation as mentally and physically demanding. The pair had hoped to repeat the experience, but the new medical advice has changed those plans.
Instead, they now intend to focus on shorter runs together.
The television presenter admitted she felt a surprising sense of relief at the specialist’s recommendation, recalling how intense the training had been for both of them.
A sporting life continues — just differently
Lois, a competitive showjumper and university student, has long balanced academics with elite sport. She has ridden horses since childhood and competed at national levels, later even participating in a charity jockey race — an experience she described as “brutal.”
Her diagnosis does not end her athletic pursuits, but it reshapes them.
Medical experts increasingly stress that PCOS management is not about stopping exercise but tailoring it. Sustainable training, adequate recovery, and balanced nutrition often produce better long-term hormonal outcomes than relentless endurance performance.
For athletes with PCOS, the goal shifts from pushing physical limits to supporting physiological stability — a change that, doctors say, can ultimately protect both performance and health.
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