The global obesity epidemic, affecting over one billion people worldwide, is largely driven by eating behaviors. Appetite, influenced by both intrinsic and environmental factors, plays a crucial role in weight management. A recent study how exercise affects appetite perception in obese males, shedding light on the physiological mechanisms behind hunger suppression post-exercise.

While exercise is well-known for its benefits in weight management, its direct impact on appetite control has remained a subject of debate. Appetite is regulated by a complex network of gastrointestinal and neurohormonal signals, including hormones like ghrelin, leptin, interleukin 6 (IL-6), and neuropeptide Y (NPY). These hormones influence hunger levels, satiety, and energy balance.

The study published in Physiological Reports examines investigated how moderate continuous aerobic exercise (MICE) alters these hormone levels in obese men, ultimately affecting their hunger perception. The findings reveal that certain myokines and cytokines shift dynamically post-exercise, potentially reducing appetite and offering a promising strategy for weight management.

Hormonal Responses to Exercise

The study found that after exercise, there was a significant increase in IL-6 and irisin levels in the exercise group compared to those who remained sedentary. These elevated concentrations persisted for an hour after working out. IL-6 has been associated with regulating metabolism and enhancing fat oxidation, while irisin plays a role in converting white fat into more metabolically active brown fat.

Conversely, the study reported a decrease in neuropeptide Y (NPY) levels, a key neurotransmitter responsible for stimulating appetite. The decline in NPY levels post-exercise suggests a temporary suppression of hunger, supporting the idea that exercise can curb cravings. However, the study did not observe significant changes in IL-7 or leptin levels, two other hormones involved in appetite regulation.

Why Some People Struggle to Lose Weight

Ghrelin, often called the “hunger hormone,” stimulates appetite by increasing activity in specific areas of the brain. Individuals with higher ghrelin levels generally find it harder to lose weight because their bodies signal hunger more frequently.

Research suggests that dieting can lead to an increase in ghrelin levels, making weight loss challenging. Certain medical conditions, such as Hashimoto’s thyroiditis, Prader-Willi syndrome, anorexia nervosa, and bulimia nervosa, are also linked to elevated ghrelin levels, complicating appetite regulation further.

Challenges in Implementing Exercise for Appetite Control

While exercise has clear benefits, the findings should be interpreted with caution. He pointed out that the study had a small sample size, making it difficult to draw definitive conclusions.

Moreover, he highlighted the challenges faced by obese individuals in maintaining an intensive exercise routine. While exercise-induced appetite suppression is promising, consistently engaging in high-intensity workouts may be unrealistic for those who struggle with mobility or fitness levels. More extensive studies are needed to determine the optimal exercise duration and intensity for effective appetite suppression.

Tips to Naturally And Safely Suppressing Appetite

Besides exercise, there are several strategies individuals can use to naturally suppress their appetite and improve satiety:

Increase Protein Intake: Protein-rich foods, such as lean meats, legumes, and dairy, promote feelings of fullness and reduce hunger.

Stay Hydrated: Drinking water before meals can help control portion sizes and prevent overeating.

Opt for Fiber-Rich Foods: Whole grains, vegetables, and fruits high in fiber take longer to digest, keeping you full for longer.

Reduce Simple Carbohydrates and Sugars: Simple carbs and sugars cause rapid spikes and crashes in blood sugar levels, leading to increased hunger.

Prioritize Sleep: Poor sleep disrupts hunger-regulating hormones, making it harder to control cravings.

Manage Stress: Chronic stress increases cortisol levels, which can lead to overeating and weight gain.

The study’s findings indicate that moderate exercise can temporarily suppress appetite by altering key hormones. While more research is needed to refine the details—such as optimal workout duration and intensity—this insight adds to the growing body of evidence supporting exercise as a tool for appetite regulation and weight management.

For individuals looking to curb cravings and maintain a healthy weight, incorporating a well-balanced diet alongside regular exercise remains the most sustainable approach. Future studies focusing on larger populations and long-term effects could provide deeper insights into how exercise can be optimized for appetite control, making it an effective strategy in combating obesity.

Exercise alone is not a magic solution for weight loss, but its impact on appetite hormones presents a promising avenue for managing hunger and energy balance. As research continues to evolve, it becomes increasingly clear that integrating physical activity with mindful eating habits can play a vital role in achieving and maintaining a healthy lifestyle.

A person's body mass index (BMI) may seem normal while they may already be at a significant metabolic risk. According to experts at the first AIIMS Obesity Summit in New Delhi, which is themed “Decoding Obesity: Biology to Remedy,” this is particularly observed frequently among South Asians.

Addressing the summit on Saturday, AIIMS Director Dr Nikhil Tandon said obesity cannot be understood simply through numbers. He argued that doctors need to look beyond weight and BMI to understand where fat is distributed in the body and how the individual's overall health is affected due to the additional fat.

“People will say, you know, subcutaneous is all right, visceral is bad,” Tandon said, referring to the difference between fat stored under the skin and fat accumulated around internal organs. He said that while measures like waist circumference remain essential, they do not fully capture the complete complexity of obesity.

South Asians Face Higher Metabolic Risk Even At Lower BMI

Tandon spoke about how South Asians can develop metabolic issues at lower BMI levels because of differences in fat distribution in the body. “A lot of people of South Asian descent may not qualify as people who are obese, but because of central disposition of fat, they can have metabolic, maybe metabolically unhealthy at very, very low BMIs,” he said.

He compared the body types and prevalence of lifestyle disorders in South Asians and Pima Indians, mentioning that South Asians showed a substantially higher incidence of diabetes at lower BMI levels. He said that obesity should not be assessed solely by what we see on the weighing scale.

“If at similar numbers, two people have very different health outcomes, then you have to understand the reason for the difference in health outcomes rather than be fixated in the number,” Tandon said.

Also read: Thin Outside, Fat Inside: Why A Slim Body May Still Hide Metabolic Health Risks?

Obesity Does Not Occur Due To Willpower Issue

The summit's discussions also challenged the idea that obesity can be managed by just eating less and exercising more.

Prof Naveet Wig, patron of the summit, shared his own experience of repeatedly gaining and losing weight, explaining that his experience had reinforced the complexity of obesity.

“It is a relapsing disease. It is a relapsing problem. It is a chronic problem,” he said, adding that obesity involves multiple factors including genetics, environment, behaviour, sleep, muscle, adipose tissue, the gut and the brain.

He also cautioned against using medication like GLP-1 as many may turn it into a substitute for comprehensive obesity care. “We can't let drug become a doctor,” Wig said, stressing the importance of nutrition, exercise, sleep and preservation of muscle mass.

He noted that modern obesity care now includes GLP-1 therapies, including oral options, as well as surgical treatments. He questioned whether enough attention is being paid to nutrition, muscle preservation and sleep when these treatments are used.

Also read: Can You Really Lose 5 Kg In A Week With Just 4 Minutes Of Exercise? Japan's Viral Workout Explained

Prevention May Need To Start Much Earlier

Tandon also stressed that obesity prevention cannot begin late in adulthood. He explained that body weight, blood pressure, cholesterol and glucose tend to follow patterns established early in life. Major changes in these trajectories could be due to underlying influences that need to be addressed.

“You don't go to sleep at night with a BMI of 23 and wake up with a BMI of 30,” he said, explaining that obesity as a process that develops over time.

He argued that eating habits, physical activity and other behavioural patterns become established early, making childhood and early-life interventions particularly important.

Ultimately, Tandon said, preventing weight gain in the first place may be easier than trying to reverse obesity later.

“Once you become obese, it's incredibly difficult to lose weight. And once you lose weight, it's incredibly difficult to sustain that weight loss,” he said.

The experts say that obesity treatment should focus not simply on making patients lighter, but on making them healthier by paying attention to metabolic health, fitness, nutrition, muscle mass, sleep and long-term sustainability.

For years, the weighing scale has been one of the simplest ways to assess health. A person with a “normal” Body Mass Index (BMI) is often considered healthy, while being overweight or obese is viewed as the primary warning sign. But what if someone looks slim on the outside and still carries a significant metabolic risk on the inside?

This is where the concept of TOFI—“Thin Outside, Fat Inside” becomes important. TOFI describes individuals who may have a normal BMI or appear lean but carry a higher proportion of visceral fat—fat stored deep inside the abdomen around vital organs. Unlike the visible fat under the skin, visceral fat is metabolically active and can contribute to inflammation, insulin resistance and other metabolic abnormalities.

Research has shown that Asian Indians tend to develop abdominal and visceral fat at lower BMI levels compared with several other ethnic groups. They may also have relatively lower muscle mass. As a result, a person can appear slim, have a seemingly reassuring weight, and yet have an increased risk of metabolic disease.

Why does this matter?

Also read: From Insulin Resistance to Fertility: Understanding the Metabolic Side of PCOS

The important message is that BMI alone does not tell the complete story. BMI measures weight in relation to height, but it does not distinguish between muscle and fat or indicate where fat is stored. That is why measurements such as waist circumference can provide valuable additional information. A larger waist can indicate increased abdominal fat and may signal higher cardiometabolic risk even when BMI falls within the normal range.

Being normal weight does not automatically mean being TOFI. However, people with a sedentary lifestyle, low muscle mass, increasing waist circumference, family history of diabetes, unhealthy dietary patterns, poor sleep or metabolic abnormalities may warrant closer assessment.

Simple health checks such as blood pressure, fasting glucose or HbA1c and lipid profile can provide important clues. Depending on the individual and clinical situation, doctors may also recommend assessment of liver health or body composition.

What can we do?

The solution is not simply to focus on losing kilograms. For a normal-weight person carrying excess visceral fat, the goal should be to improve body composition and metabolic health. Regular physical activity—particularly strength training combined with aerobic exercise—can help build or preserve muscle and improve insulin sensitivity.

A balanced diet rich in vegetables, whole grains, pulses, adequate protein and fibre, while limiting excess refined carbohydrates, sugary foods and ultra-processed foods, is equally important. Adequate sleep, stress management and avoiding prolonged sedentary periods are also essential components of metabolic health.

By Dr Farah Ingale, Director - Internal Medicine & Consultant – Diabetologist, Fortis Hiranandani Hospital, Navi Mumbai

We have always been told that truly sustainable weight loss is a long-term process made up of daily physical activity, healthy eating, and regular sleep. However, a four-minute workout from Japan, which has taken social media by storm, has confidently challenged this idea.

Making an ambitious promise, the makers of the workout claim that one can lose around 5 kg in just one week with the 4-minute workout.

The video, which was reshared on social media, has crossed 3 million views on X, with nearly 60,000 likes, has sparked a debate whether the short routine could really replace a longer gym session.

The virality of the video makes sense. Most of us argue with ourselves everyday, trying to talk ourselves out of going to the gym and spending hours toiling away. But do we realistically need just a few minutes to get in shape?

You don't need dumbbells, gym membership, or any special equipment to do this workout routine. You can apparently do it almost anywhere.

Can You Actually Lose 5 Kg In 7 Days?

Also read: Novak Djokovic’s Health Struggles At US Open: Are The Demands Of Elite Tennis Becoming Too Much?

There is no evidence that four minutes of exercise a day can make someone lose 5 kg of body weight in seven days. The viral claim comes from the makers of the video, rather than a clinical study showing that people following the routine lost 5 kg in a week.

Experts also say that such a drastic amount of weight loss in seven days is not realistically achievable for most people.

Additionally, what appears on the weighing scale can also move up or down because of water retention, food in the digestive system, and other short-term changes. A sudden drop in weight therefore does not necessarily mean that 5 kg of body fat has disappeared.

Losing considerable body fat needs more than just a 'very short workout'. Along with at least 30 minutes of physical activity, one needs a sustained calorie deficit.

The Four Minutes Of Exercise Is Not Completely Useless

Also read: What Is Zone 2 Cardio? The Workout Everyone Is Talking About

Now as the facts are clear, we would be remiss to not appreciate the routine's biggest potential, which is getting inactive people to move, not weight loss.

Four minutes of activity is certainly better than spending those four minutes sitting still. If a short routine like this Japanese workout feels manageable enough to turn it into a daily habit, it can give you a starting point for physical activity, which you can gradually increase.

But one needs to be careful. A short workout routine usually makes your heart work harder. If you experience pain, dizziness, chest discomfort, or an irregular heartbeat, you must stop immediately.

People who are new to exercise or have existing health concerns should speak with a doctor before starting a new routine.

How To Lose Weight Safely?

Rather than trying to take a shortcut and achieve a drastic weight loss in less days, opt for a more sustainable approach is to gradually increase daily movement and combine it with a balanced diet.