The global obesity epidemic, affecting over one billion people worldwide, is largely driven by eating behaviors. Appetite, influenced by both intrinsic and environmental factors, plays a crucial role in weight management. A recent study how exercise affects appetite perception in obese males, shedding light on the physiological mechanisms behind hunger suppression post-exercise.

While exercise is well-known for its benefits in weight management, its direct impact on appetite control has remained a subject of debate. Appetite is regulated by a complex network of gastrointestinal and neurohormonal signals, including hormones like ghrelin, leptin, interleukin 6 (IL-6), and neuropeptide Y (NPY). These hormones influence hunger levels, satiety, and energy balance.

The study published in Physiological Reports examines investigated how moderate continuous aerobic exercise (MICE) alters these hormone levels in obese men, ultimately affecting their hunger perception. The findings reveal that certain myokines and cytokines shift dynamically post-exercise, potentially reducing appetite and offering a promising strategy for weight management.

Hormonal Responses to Exercise

The study found that after exercise, there was a significant increase in IL-6 and irisin levels in the exercise group compared to those who remained sedentary. These elevated concentrations persisted for an hour after working out. IL-6 has been associated with regulating metabolism and enhancing fat oxidation, while irisin plays a role in converting white fat into more metabolically active brown fat.

Conversely, the study reported a decrease in neuropeptide Y (NPY) levels, a key neurotransmitter responsible for stimulating appetite. The decline in NPY levels post-exercise suggests a temporary suppression of hunger, supporting the idea that exercise can curb cravings. However, the study did not observe significant changes in IL-7 or leptin levels, two other hormones involved in appetite regulation.

Why Some People Struggle to Lose Weight

Ghrelin, often called the “hunger hormone,” stimulates appetite by increasing activity in specific areas of the brain. Individuals with higher ghrelin levels generally find it harder to lose weight because their bodies signal hunger more frequently.

Research suggests that dieting can lead to an increase in ghrelin levels, making weight loss challenging. Certain medical conditions, such as Hashimoto’s thyroiditis, Prader-Willi syndrome, anorexia nervosa, and bulimia nervosa, are also linked to elevated ghrelin levels, complicating appetite regulation further.

Challenges in Implementing Exercise for Appetite Control

While exercise has clear benefits, the findings should be interpreted with caution. He pointed out that the study had a small sample size, making it difficult to draw definitive conclusions.

Moreover, he highlighted the challenges faced by obese individuals in maintaining an intensive exercise routine. While exercise-induced appetite suppression is promising, consistently engaging in high-intensity workouts may be unrealistic for those who struggle with mobility or fitness levels. More extensive studies are needed to determine the optimal exercise duration and intensity for effective appetite suppression.

Tips to Naturally And Safely Suppressing Appetite

Besides exercise, there are several strategies individuals can use to naturally suppress their appetite and improve satiety:

Increase Protein Intake: Protein-rich foods, such as lean meats, legumes, and dairy, promote feelings of fullness and reduce hunger.

Stay Hydrated: Drinking water before meals can help control portion sizes and prevent overeating.

Opt for Fiber-Rich Foods: Whole grains, vegetables, and fruits high in fiber take longer to digest, keeping you full for longer.

Reduce Simple Carbohydrates and Sugars: Simple carbs and sugars cause rapid spikes and crashes in blood sugar levels, leading to increased hunger.

Prioritize Sleep: Poor sleep disrupts hunger-regulating hormones, making it harder to control cravings.

Manage Stress: Chronic stress increases cortisol levels, which can lead to overeating and weight gain.

The study’s findings indicate that moderate exercise can temporarily suppress appetite by altering key hormones. While more research is needed to refine the details—such as optimal workout duration and intensity—this insight adds to the growing body of evidence supporting exercise as a tool for appetite regulation and weight management.

For individuals looking to curb cravings and maintain a healthy weight, incorporating a well-balanced diet alongside regular exercise remains the most sustainable approach. Future studies focusing on larger populations and long-term effects could provide deeper insights into how exercise can be optimized for appetite control, making it an effective strategy in combating obesity.

Exercise alone is not a magic solution for weight loss, but its impact on appetite hormones presents a promising avenue for managing hunger and energy balance. As research continues to evolve, it becomes increasingly clear that integrating physical activity with mindful eating habits can play a vital role in achieving and maintaining a healthy lifestyle.

Aging brings a shift in how the body functions. Metabolism slows down, hormones fluctuate, and the risk of conditions such as diabetes, heart disease, joint problems, and bone loss begins to rise. Health experts often describe the 40s as a turning point, a decade where prevention matters more than ever. According to US-based longevity doctor Dr Vassily Eliopoulos, many habits that feel harmless in one’s 20s and 30s begin to show their impact sharply after the age of 40.

In a recent Instagram post, Dr Eliopoulos highlighted five things people should stop doing immediately if they want to protect their long-term health. He wrote that this is the decade to take muscle health seriously, make sleep a priority, and let go of small daily habits that quietly speed up aging. He added that the choices made in the 40s decide how well the body functions in the 50s, 60s, and 70s because preventing damage is always easier than trying to repair it later.

Stop cutting back on sleep

Sleep becomes crucial in the 40s because the body needs more time to repair itself. Dr Eliopoulos explains that adults between 40 and 60 require seven to nine hours of sleep every night to maintain hormone balance, protect cognitive function, and support metabolism. Even losing a single hour can make a difference. Research shows the risk of type 2 diabetes, heart disease, and faster brain aging rises for every hour of sleep below the seven-hour mark. Chronic lack of sleep also encourages fat storage around the abdomen, weakens the immune system, and slows recovery after daily activities.

Simple habits such as keeping the room dark and cool, avoiding late-night screen time, and sticking to a regular sleep schedule can make sleep more restorative. Dr Eliopoulos describes good sleep as a free nightly hormone reset.

Stop neglecting strength training

Muscle loss is one of the most predictable changes after 40. According to Dr Eliopoulos, adults lose three to eight percent of their muscle mass each decade unless they actively work against it. Resistance training two to four times a week can slow this decline dramatically.

Strength work helps maintain bone density, improves insulin sensitivity, and builds lean muscle. Exercises such as squats, push-ups, weightlifting, or using resistance bands increase stability, balance, and overall metabolic rate. Studies also show that middle-aged adults build strength more efficiently with resistance training than relying on cardio alone.

Stop relying on highly processed foods

Packaged snacks, sugary drinks, instant meals, and ultra-processed foods can have a much bigger impact in midlife. More than half of adults over 40 struggle with obesity linked to these foods. They cause sudden spikes in blood sugar and promote inflammation, raising the risk of heart failure. These foods also lack fibre, which affects gut health and increases the risk of colon cancer. Brain health is not spared either, with several studies linking diets high in processed food to faster cognitive decline.

Switching to whole foods such as fruit, nuts, vegetables, and yoghurt can help stabilise energy levels and reduce the risk of diabetes. Reading labels to avoid additives and hidden sugars is an important habit at this stage.

Stop delaying routine health tests

Once a person enters their 40s, regular health screenings become essential. Many conditions, including high cholesterol, prediabetes, thyroid disorders, and vitamin deficiencies, develop silently. Monitoring levels such as A1C, lipid profiles, thyroid markers, and vitamin D helps detect issues early, allowing interventions before symptoms show up. Avoiding tests often means missing warning signs until fatigue, pain, or more serious complications appear.

Stop letting stress build up

Stress hits harder in the 40s because the body becomes more sensitive to cortisol. Continuous stress can raise blood pressure, increase inflammation, affect memory, and contribute to anxiety. Long-term stress even accelerates cellular aging and can push biological age forward by several years. When paired with poor sleep or unhealthy eating, stress significantly increases the risk of stroke.

Dr Eliopoulos recommends daily breathing exercises, regular walks, and simple meditation practices to help reduce stress and protect long-term health.

Disclaimer: Please note that this is a user-generated content. Health and Me does not encourage any changes to be made in your daily schedule without consulting your doctor.

A New York City teacher Pedro Soto, 56, who teachers at the Manhattan school had a simple sore throat and he believed it was from a viral infection, but it soon turned out to be type 2 diabetes.

This was in April 2024, when he went to his doctor with the complaint of a sore throat and took a blood test. This is when he was "officially diagnosed with type 2 diabetes".

In an interview with PEOPLE, he tells while the doctor recommended medications for him, he was determined to make a lifestyle change first. "After receiving the news, I chose not to start medication right away. Instead, I committed to exercising, running twice a week and improving my diet."

Turns out, running, changed his life.

Running With Diabetes: Soto's Determination To Change His Life(style)

Pedro Soto first considered running the TCS NYC Marathon after a colleague mentioned that her husband had completed it. Motivated, he applied through a special program for teachers, sharing an essay about his type 2 diabetes diagnosis. His story earned him a spot on the team. As he trained, he closely monitored his health, undergoing regular blood tests every three months. The improvement surprised him. His blood sugar levels, once concerning, gradually returned to the normal range. While type 2 diabetes cannot be fully cured, it can be reversed, and Soto was seeing that transformation firsthand.

Training Through The Tough Times

The marathon was scheduled for November 2, 2025. Soto’s training, however, didn’t begin smoothly. In June, he learned he had Lyme disease. Around the same time, he lost his father. Because of these back-to-back challenges, he wasn't able to train consistently until August. Running soon became more than exercise. It became a way to navigate grief and rebuild strength.

He describes those months as emotionally heavy. Running offered him space to reflect, heal, and feel close to his father. It became a ritual that allowed him to confront his feelings rather than avoid them.

Experiencing the Race

To prepare mentally, Soto dove into YouTube videos and articles about the marathon. Still, nothing compared to the real thing. To him, race day felt like a citywide block party. The cheering crowds, music, and energy made the pain more bearable. He said that although the long hours of pounding take a toll on joints and muscles, the city's encouragement kept pushing him forward.

Finding Strength in His Students

The toughest stretch came in the final six miles, when self-doubt crept in. What kept him going was thinking about his students. Soto works with teenagers in a transfer program, many of whom have struggled in traditional school systems. Their perseverance inspired him. If his students could show up every day despite their challenges, he believed he could finish the race.

He says he is taking care of his health and this itself is an act of commitment to his students. Whenever he feels healthier, he shows up as a strong educator and for him the marathon teaches him the importance one needs in life of balance, self-care, and knowing when to put themselves first.

"I'm excited for this next chapter in my life, I'm the happiest I've ever been, and for since I could remember I was sad," said Post Malone as he talked about his journey of losing 55 pounds. He went from 240 lbs to 185 lbs, he revealed at The Joe Rogan Experience Podcast. His inspiration? His daughter. He said that he is focused more on his health since becoming a father.

"It is definitely made me take better care of myself. I want to be around to see her go and do kick-*ss stuff. And before, you know, I was really drinking a lot and smoking a lot and stuff. I kind of took everything and toned it down a little bit and, you know, doing my best and really got my weight going," he said.

His weight loss journey started after he welcomed his daughter in May 2022, and on April 20233, he shared on his Instagram that post becoming a father he is now prioritizing his health.

How Did Post Malone Lose So Much Weight?

He said it is simple, he decided to "kick soda and start eating better". He also is trying to cut down his smokes and brews or give up completely, which is taking time.

On his Instagram post, he wrote: "I've had a lot of people ask me about my weight loss and I'd suppose, performance on stage. I'm having a lot of fun performing, and have never felt healthier. I guess dad life kicked in and I decided to kick soda and start eating better so I can be around for a long time for this little angel. Next up is smokes and brews, but I like to consider myself a patient man... lol!"

While his fans were initially concerned about his weight loss, he reassured them that his "brain is in a super dope place" and he was "the happiest" he has ever been in a long time.

When he made his appearance in June 2024, on The Joe Rogan Experience Podcast, he said that his fans in fact, thought, that he started using drugs, due to his drastic weight loss. This is why he posted on Instagram to deny those allegations. “I remember, whenever I started losing my weight, everybody was like, ‘Hey, this is what meth looks like,’ and I started dancing on stage and having fun and having more energy and just enjoying life again, you know what I mean,” he told host Joe Rogan. “Like I mentioned, I was s***** for a long time, but I had my baby and I’m in a great f****** spot and then the first thing that happens is like, ‘Oh he’s on f****** drugs.’"

However, Malone has confirmed that he is not "any hard drugs".

What Helped Malone Lose 55 Pounds?

In an appearance on The Howard Stern Show in October 2023, Malone said that he has not been on weight loss medication, rather he is now making better food choices.

Earlier, whenever he was on tour, he would go for junk, but now, he has made a deliberate choice to eat "grilled chicken" "carrots" with a "little bit of white rice with hot sauce". He said he was blown away to find out that hot sauce has no calories.

He also shared that he has cut out fried food and pizza. He shared that he would previously eat a lot of junk while on tour, especially because those places were open at 2 am after a show. However, when he made those small dietary changes, he lost 20 pounds, which made him think "let's keep building".

He also shared that he started cutting down on his soda intake. However, he would occasionally reward himself with one after a show.

He also showed off his weight loss in an August 2023 Instagram post on a mirror selfie and wrote: "Introducing Viceroy Chungus VonBattlepass, i love you," in caption.